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Pesquisa : B03.440.400.425.550.550.660 [Categoria DeCS]
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  1 / 23 MEDLINE  
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[PMID]:25291599
[Au] Autor:Jaehme M; Guskov A; Slotboom DJ
[Ad] Endereço:University of Groningen, Groningen Biomolecular Sciences and Biotechnology Institute, Groningen, the Netherlands.
[Ti] Título:Crystal structure of the vitamin B3 transporter PnuC, a full-length SWEET homolog.
[So] Source:Nat Struct Mol Biol;21(11):1013-5, 2014 Nov.
[Is] ISSN:1545-9985
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:PnuC transporters catalyze cellular uptake of the NAD+ precursor nicotinamide riboside (NR) and belong to a large superfamily that includes the SWEET sugar transporters. We present a crystal structure of Neisseria mucosa PnuC, which adopts a highly symmetrical fold with 3+1+3 membrane topology not previously observed in any protein. The high symmetry of PnuC with a single NR bound in the center suggests a simple alternating-access translocation mechanism.
[Mh] Termos MeSH primário: Proteínas de Bactérias/química
Neisseria mucosa/química
Niacinamida/análogos & derivados
Niacinamida/química
[Mh] Termos MeSH secundário: Sequência de Aminoácidos
Proteínas de Bactérias/genética
Sítios de Ligação
Transporte Biológico
Sequência Conservada
Cristalografia por Raios X
Escherichia coli/genética
Escherichia coli/metabolismo
Expressão Gênica
Modelos Moleculares
Dados de Sequência Molecular
Neisseria mucosa/metabolismo
Ligação Proteica
Conformação Proteica
Dobramento de Proteína
Proteínas Recombinantes/química
Proteínas Recombinantes/genética
Homologia de Sequência de Aminoácidos
Especificidade por Substrato
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (Bacterial Proteins); 0 (Recombinant Proteins); 0I8H2M0L7N (nicotinamide-beta-riboside); 25X51I8RD4 (Niacinamide)
[Em] Mês de entrada:1501
[Cu] Atualização por classe:171116
[Lr] Data última revisão:
171116
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:141008
[St] Status:MEDLINE
[do] DOI:10.1038/nsmb.2909


  2 / 23 MEDLINE  
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[PMID]:23905778
[Au] Autor:Mechergui A; Achour W; Baaboura R; Ouertani H; Lakhal A; Torjemane L; Othman TB; Hassen AB
[Ad] Endereço:Service des Laboratoires, Centre National de Greffe de Moelle Osseuse de Tunis, Tunis, Tunisie.
[Ti] Título:Case report of bacteremia due to Neisseria mucosa.
[So] Source:APMIS;122(4):359-61, 2014 Apr.
[Is] ISSN:1600-0463
[Cp] País de publicação:Denmark
[La] Idioma:eng
[Ab] Resumo:Neisseria mucosa, a Gram-negative diplococcus, is part of normal nasopharyngeal flora. We report a case of bacteremia caused by N. mucosa in a 50-year-old neutropenic patient suffering from non-secretory multiple myeloma stage IIIA. This case underscores that mostly nonpathogenic N. mucosa can cause bacteremia in neutropenic patients who developed mucositis after hematopoietic stem cell transplantation.
[Mh] Termos MeSH primário: Bacteriemia/etiologia
Neisseria mucosa/patogenicidade
Infecções por Neisseriaceae/etiologia
[Mh] Termos MeSH secundário: Bacteriemia/microbiologia
Feminino
Transplante de Células-Tronco Hematopoéticas/efeitos adversos
Seres Humanos
Hospedeiro Imunocomprometido
Meia-Idade
Mieloma Múltiplo/complicações
Mieloma Múltiplo/terapia
Neisseria mucosa/classificação
Neisseria mucosa/genética
Infecções por Neisseriaceae/microbiologia
Neutropenia/complicações
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Em] Mês de entrada:1404
[Cu] Atualização por classe:140305
[Lr] Data última revisão:
140305
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:130803
[St] Status:MEDLINE
[do] DOI:10.1111/apm.12144


  3 / 23 MEDLINE  
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[PMID]:24097834
[Au] Autor:Bennett JS; Jolley KA; Maiden MC
[Ad] Endereço:Department of Zoology, University of Oxford, Oxford OX1 3PS, UK.
[Ti] Título:Genome sequence analyses show that Neisseria oralis is the same species as 'Neisseria mucosa var. heidelbergensis'.
[So] Source:Int J Syst Evol Microbiol;63(Pt 10):3920-6, 2013 Oct.
[Is] ISSN:1466-5034
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Phylogenies generated from whole genome sequence (WGS) data provide definitive means of bacterial isolate characterization for typing and taxonomy. The species status of strains recently defined with conventional taxonomic approaches as representing Neisseria oralis was examined by the analysis of sequences derived from WGS data, specifically: (i) 53 Neisseria ribosomal protein subunit (rps) genes (ribosomal multi-locus sequence typing, rMLST); and (ii) 246 Neisseria core genes (core genome MLST, cgMLST). These data were compared with phylogenies derived from 16S and 23S rRNA gene sequences, demonstrating that the N. oralis strains were monophyletic with strains described previously as representing 'Neisseria mucosa var. heidelbergensis' and that this group was of equivalent taxonomic status to other well-described species of the genus Neisseria. Phylogenetic analyses also indicated that Neisseria sicca and Neisseria macacae should be considered the same species as Neisseria mucosa and that Neisseria flavescens should be considered the same species as Neisseria subflava. Analyses using rMLST showed that some strains currently defined as belonging to the genus Neisseria were more closely related to species belonging to other genera within the family; however, whole genome analysis of a more comprehensive selection of strains from within the family Neisseriaceae would be necessary to confirm this. We suggest that strains previously identified as representing 'N. mucosa var. heidelbergensis' and deposited in culture collections should be renamed N. oralis. Finally, one of the strains of N. oralis was able to ferment lactose, due to the presence of ß-galactosidase and lactose permease genes, a characteristic previously thought to be unique to Neisseria lactamica, which therefore cannot be thought of as diagnostic for this species; however, the rMLST and cgMLST analyses confirm that N. oralis is most closely related to N. mucosa.
[Mh] Termos MeSH primário: Neisseria mucosa/classificação
Filogenia
[Mh] Termos MeSH secundário: Técnicas de Tipagem Bacteriana
DNA Bacteriano/genética
Genes Bacterianos
Tipagem de Sequências Multilocus
Neisseria mucosa/genética
RNA Ribossômico 16S/genética
RNA Ribossômico 23S/genética
Proteínas Ribossômicas/genética
Análise de Sequência de DNA
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (DNA, Bacterial); 0 (RNA, Ribosomal, 16S); 0 (RNA, Ribosomal, 23S); 0 (Ribosomal Proteins)
[Em] Mês de entrada:1312
[Cu] Atualização por classe:170922
[Lr] Data última revisão:
170922
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:131008
[St] Status:MEDLINE
[do] DOI:10.1099/ijs.0.052431-0


  4 / 23 MEDLINE  
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[PMID]:23714165
[Au] Autor:Fernandez-Feo M; Wei G; Blumenkranz G; Dewhirst FE; Schuppan D; Oppenheim FG; Helmerhorst EJ
[Ad] Endereço:Department of Periodontology and Oral Biology, Boston University Henry M. Goldman School of Dental Medicine, Boston, MA 02118, USA.
[Ti] Título:The cultivable human oral gluten-degrading microbiome and its potential implications in coeliac disease and gluten sensitivity.
[So] Source:Clin Microbiol Infect;19(9):E386-94, 2013 Sep.
[Is] ISSN:1469-0691
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Coeliac disease is characterized by intestinal inflammation caused by gluten, proteins which are widely contained in the Western diet. Mammalian digestive enzymes are only partly capable of cleaving gluten, and fragments remain that induce toxic responses in patients with coeliac disease. We found that the oral microbiome is a novel and rich source of gluten-degrading organisms. Here we report on the isolation and characterization of the cultivable resident oral microbes that are capable of cleaving gluten, with special emphasis on the immunogenic domains. Bacteria were obtained by a selective culturing approach and enzyme activities were characterized by: (i) hydrolysis of paranitroanilide-derivatized gliadin-derived tripeptide substrates; (ii) gliadin degradation in-gel (gliadin zymography); (iii) gliadin degradation in solution; (iv) proteolysis of the highly immunogenic α-gliadin-derived 33-mer peptide. For selected strains pH activity profiles were determined. The culturing strategy yielded 87 aerobic and 63 anaerobic strains. Species with activity in at least two of the four assays were typed as: Rothia mucilaginosa HOT-681, Rothia aeria HOT-188, Actinomyces odontolyticus HOT-701, Streptococcus mitis HOT-677, Streptococcus sp. HOT-071, Neisseria mucosa HOT-682 and Capnocytophaga sputigena HOT-775, with Rothia species being active in all four assays. Cleavage specificities and substrate preferences differed among the strains identified. The approximate molecular weights of the enzymes were ~75 kD (Rothia spp.), ~60 kD (A. odontolyticus) and ~150 kD (Streptococcus spp.). In conclusion, this study identified new gluten-degrading microorganisms in the upper gastrointestinal tract. A cocktail of the most active oral bacteria, or their isolated enzymes, may offer promising new treatment modalities for coeliac disease.
[Mh] Termos MeSH primário: Bactérias/enzimologia
Bactérias/isolamento & purificação
Placa Dentária/microbiologia
Gliadina/metabolismo
Microbiota
Saliva/microbiologia
[Mh] Termos MeSH secundário: Actinomyces/enzimologia
Actinomyces/isolamento & purificação
Capnocytophaga/enzimologia
Capnocytophaga/isolamento & purificação
Doença Celíaca/tratamento farmacológico
Doença Celíaca/enzimologia
Gliadina/química
Glutens/imunologia
Glutens/metabolismo
Seres Humanos
Neisseria mucosa/enzimologia
Neisseria mucosa/isolamento & purificação
Streptococcus/enzimologia
Streptococcus/isolamento & purificação
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, N.I.H., EXTRAMURAL
[Nm] Nome de substância:
8002-80-0 (Glutens); 9007-90-3 (Gliadin)
[Em] Mês de entrada:1402
[Cu] Atualização por classe:170220
[Lr] Data última revisão:
170220
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:130530
[St] Status:MEDLINE
[do] DOI:10.1111/1469-0691.12249


  5 / 23 MEDLINE  
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[PMID]:22443543
[Au] Autor:Teles FR; Teles RP; Sachdeo A; Uzel NG; Song XQ; Torresyap G; Singh M; Papas A; Haffajee AD; Socransky SS
[Ad] Endereço:Department of Periodontology, The Forsyth Institute, Cambridge, MA 02142, USA. fteles@forsyth.org
[Ti] Título:Comparison of microbial changes in early redeveloping biofilms on natural teeth and dentures.
[So] Source:J Periodontol;83(9):1139-48, 2012 Sep.
[Is] ISSN:1943-3670
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Surfaces and fluids can affect oral bacterial colonization. The aim of this study is to compare redeveloping biofilms on natural teeth and dentures. METHODS: Supragingival plaque samples were taken from 55 dentate individuals and the denture teeth of 62 edentulous individuals before and after professional cleaning. Also, samples from seven "teeth" (samples included dentures) in randomly selected quadrants were collected after 1, 2, 4, and 7 days of no oral hygiene. Samples were analyzed using checkerboard DNA-DNA hybridization. Counts and proportions of 41 bacterial taxa were determined at each time point, and significant differences were determined using the Mann-Whitney U test. Ecological succession was determined using a modified moving window analysis. RESULTS: Mean total DNA probe counts were similar precleaning but were higher in dentate individuals at all post-cleaning visits (P <0.01). Precleaning edentate biofilms had higher counts and proportions of Streptococcus mitis, Streptococcus oralis, and Streptococcus mutans, whereas dentate individuals had higher proportions of Tannerella forsythia, Selenomonas noxia, and Neisseria mucosa. By day 2, mean counts of all taxa were higher in natural teeth, and most remained higher at day 7 (P <0.01). Succession was more rapid and complex in dentate individuals. Both groups demonstrated increased proportions of S. mitis and S. oralis by day 1. N. mucosa, Veillonella parvula, and Eikenella corrodens increased in both groups, but later in samples from edentate individuals. CONCLUSIONS: "Mature" natural and denture teeth biofilms have similar total numbers of bacteria but different species proportions. Post-cleaning biofilm redevelopment is more rapid and more complex on natural teeth than on denture teeth.
[Mh] Termos MeSH primário: Biofilmes/crescimento & desenvolvimento
Prótese Total/microbiologia
Dente/microbiologia
[Mh] Termos MeSH secundário: Actinomyces/isolamento & purificação
Adulto
Idoso
Idoso de 80 Anos ou mais
Bactérias/classificação
Carga Bacteriana
Bacteroides/isolamento & purificação
Placa Dentária/microbiologia
Profilaxia Dentária
Eikenella corrodens/isolamento & purificação
Seguimentos
Fusobacterium nucleatum/isolamento & purificação
Seres Humanos
Masculino
Consórcios Microbianos/fisiologia
Meia-Idade
Neisseria mucosa/isolamento & purificação
Hibridização de Ácido Nucleico
Selenomonas/isolamento & purificação
Streptococcus mitis/isolamento & purificação
Streptococcus mutans/isolamento & purificação
Streptococcus oralis/isolamento & purificação
Streptococcus sanguis/isolamento & purificação
Dente Artificial/microbiologia
Veillonella/isolamento & purificação
Adulto Jovem
[Pt] Tipo de publicação:COMPARATIVE STUDY; JOURNAL ARTICLE; RESEARCH SUPPORT, N.I.H., EXTRAMURAL; RESEARCH SUPPORT, NON-U.S. GOV'T
[Em] Mês de entrada:1302
[Cu] Atualização por classe:161019
[Lr] Data última revisão:
161019
[Sb] Subgrupo de revista:D; IM
[Da] Data de entrada para processamento:120327
[St] Status:MEDLINE
[do] DOI:10.1902/jop.2012.110506


  6 / 23 MEDLINE  
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[PMID]:21996660
[Au] Autor:Zeigler CC; Persson GR; Wondimu B; Marcus C; Sobko T; Modéer T
[Ad] Endereço:Division of Pediatric Dentistry, Department of Dental Medicine, Karolinska Institutet, Stockholm, Sweden.
[Ti] Título:Microbiota in the oral subgingival biofilm is associated with obesity in adolescence.
[So] Source:Obesity (Silver Spring);20(1):157-64, 2012 Jan.
[Is] ISSN:1930-739X
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:To test the hypothesis whether microbiota in oral biofilm is linked with obesity in adolescents we designed this cross-sectional study. Obese adolescents (n = 29) with a mean age of 14.7 years and normal weight subjects (n = 58) matched by age and gender were examined with respect to visible plaque index (VPI%) and gingival inflammation (bleeding on probing (BOP%)). Stimulated saliva was collected. They answered a questionnaire concerning medical history, medication, oral hygiene habits, smoking habits, and sociodemographic background. Microbiological samples taken from the gingival crevice was analyzed by checkerboard DNA-DNA hybridization technique. The sum of bacterial cells in subgingival biofilm was significantly associated with obesity (P < 0.001). The link between sum of bacterial cells and obesity was not confounded by any of the studied variables (chronic disease, medication, VPI%, BOP%, flow rate of whole saliva, or meal frequency). Totally 23 bacterial species were present in approximately threefold higher amounts, on average, in obese subjects compared with normal weight controls. Of the Proteobacteria phylum, Campylobacter rectus and Neisseria mucosa were present in sixfold higher amounts among obese subjects. The association between obesity and sum of bacterial cells in oral subgingival biofilm indicates a possible link between oral microbiota and obesity in adolescents.
[Mh] Termos MeSH primário: Biofilmes
Campylobacter rectus/fisiologia
Gengiva/microbiologia
Metagenoma
Neisseria mucosa/fisiologia
Obesidade/microbiologia
Saliva/microbiologia
[Mh] Termos MeSH secundário: Adolescente
Fenômenos Fisiológicos Bacterianos
Estudos Transversais
Feminino
Seres Humanos
Masculino
Obesidade/complicações
Projetos Piloto
Inquéritos e Questionários
Suécia/epidemiologia
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Em] Mês de entrada:1204
[Cu] Atualização por classe:151119
[Lr] Data última revisão:
151119
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:111015
[St] Status:MEDLINE
[do] DOI:10.1038/oby.2011.305


  7 / 23 MEDLINE  
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[PMID]:21895662
[Au] Autor:Teles FR; Teles RP; Uzel NG; Song XQ; Torresyap G; Socransky SS; Haffajee AD
[Ad] Endereço:Department of Periodontology, The Forsyth Institute, Cambridge, MA 02142, USA.
[Ti] Título:Early microbial succession in redeveloping dental biofilms in periodontal health and disease.
[So] Source:J Periodontal Res;47(1):95-104, 2012 Feb.
[Is] ISSN:1600-0765
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:BACKGROUND AND OBJECTIVE: The development of dental biofilms after professional plaque removal is very rapid. However, it is not clear whether most bacterial species return at similar rates in periodontally healthy and periodontitis subjects or if there are differences in bacterial recolonization between supragingival and subgingival biofilms in periodontal health and disease. MATERIAL AND METHODS: Supragingival and subgingival plaque samples were taken separately from 28 teeth in 38 healthy and 17 periodontitis subjects immediately after professional cleaning. Samples were taken again from seven teeth in randomly selected quadrants after 1, 2, 4 and 7 d of no oral hygiene and analyzed using checkerboard DNA-DNA hybridization. The percentage of DNA probe counts were averaged within subjects at each time-point. Ecological succession was determined using a modified moving-window analysis. RESULTS: Succession in supragingival biofilms from subjects with periodontitis and from healthy individuals was similar. At 1 d, Streptococcus mitis and Neisseria mucosa showed increased proportions, followed by Capnocytophaga gingivalis, Eikenella corrodens, Veillonella parvula and Streptococcus oralis at 1-4 d. At 4-7 d, Campylobacter rectus, Campylobacter showae, Prevotella melaninogenica and Prevotella nigrescens became elevated. Subgingival plaque redevelopment was slower and very different from supragingival plaque redevelopment. Increased proportions were first observed for S. mitis, followed by V. parvula and C. gingivalis and, at 7 d, by Capnocytophaga sputigena and P. nigrescens. No significant increase in the proportions of periodontal pathogens was observed in any of the clinical groups or locations. CONCLUSION: There is a defined order in bacterial species succession in early supragingival and subgingival biofilm redevelopment after professional cleaning.
[Mh] Termos MeSH primário: Biofilmes/classificação
Placa Dentária/microbiologia
Periodontite/microbiologia
Periodonto/microbiologia
[Mh] Termos MeSH secundário: Adulto
Carga Bacteriana
Campylobacter/classificação
Campylobacter rectus/isolamento & purificação
Capnocytophaga/classificação
DNA Bacteriano/análise
Placa Dentária/terapia
Índice de Placa Dentária
Profilaxia Dentária
Raspagem Dentária
Eikenella corrodens/isolamento & purificação
Feminino
Gengiva/microbiologia
Seres Humanos
Masculino
Interações Microbianas
Neisseria mucosa/isolamento & purificação
Hibridização de Ácido Nucleico
Índice Periodontal
Prevotella melaninogenica/isolamento & purificação
Prevotella nigrescens/isolamento & purificação
Aplainamento Radicular
Streptococcus mitis/isolamento & purificação
Streptococcus oralis/isolamento & purificação
Veillonella/isolamento & purificação
[Pt] Tipo de publicação:COMPARATIVE STUDY; JOURNAL ARTICLE; RESEARCH SUPPORT, N.I.H., EXTRAMURAL; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (DNA, Bacterial)
[Em] Mês de entrada:1206
[Cu] Atualização por classe:161122
[Lr] Data última revisão:
161122
[Sb] Subgrupo de revista:D; IM
[Da] Data de entrada para processamento:110908
[St] Status:MEDLINE
[do] DOI:10.1111/j.1600-0765.2011.01409.x


  8 / 23 MEDLINE  
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[PMID]:21605286
[Au] Autor:Bizhang M; Ellerbrock B; Preza D; Raab W; Singh P; Beikler T; Henrich B; Zimmer S
[Ad] Endereço:Department of Operative and Preventive Dentistry, University Witten/Herdecke, Witten, Germany. mozhgan.bizhang@uni-wh.de
[Ti] Título:Detection of nine microorganisms from the initial carious root lesions using a TaqMan-based real-time PCR.
[So] Source:Oral Dis;17(7):642-52, 2011 Oct.
[Is] ISSN:1601-0825
[Cp] País de publicação:Denmark
[La] Idioma:eng
[Ab] Resumo:OBJECTIVE: The purpose of this study was to quantify nine selected cariogenic bacteria in plaque from sound root surfaces and initial carious root lesions using TaqMan PCR and to analyse a putative dependence on the kind of initial periodontal treatment. MATERIAL AND METHODS: Fifty-four subjects with generalized chronic periodontitis were randomly allocated to one of the following initial periodontal therapies: full-mouth disinfection, full-mouth scaling and root planing or scaling and root planing within 7 days. Plaque samples were taken before and after periodontal treatment and analysed by TaqMan PCR. RESULTS: The quantity of the cariogenic bacteria Actinomyces spp., Streptococcus mutans, Streptococcus sobrinus, Lactobacilllus spp., Rothia dentocariosa, Parvimonas micra, Propionibacterium acnes and Neisseria mucosa were significantly higher, while the quantity of Veillonella parvula was significantly lower on initial carious lesions than on the sound surfaces both before and after periodontal therapy. No significant differences could be found in any of the tested bacteria except P. micra on initial carious lesions and sound surfaces for both examinations between the groups. CONCLUSION: All the nine species analysed were found to be present in initial carious root lesions as well as sound root surfaces but in different quantities, independent of the different periodontal therapies.
[Mh] Termos MeSH primário: Bactérias Gram-Negativas/classificação
Bactérias Gram-Positivas/classificação
Reação em Cadeia da Polimerase em Tempo Real/métodos
Cárie Radicular/microbiologia
[Mh] Termos MeSH secundário: Actinomyces/isolamento & purificação
Actinomycetaceae/isolamento & purificação
Anti-Infecciosos Locais/uso terapêutico
Carga Bacteriana
Clorexidina/análogos & derivados
Clorexidina/uso terapêutico
Periodontite Crônica/microbiologia
Periodontite Crônica/terapia
Sondas de DNA
Placa Dentária/microbiologia
Raspagem Dentária
Feminino
Seres Humanos
Lactobacillus/isolamento & purificação
Masculino
Meia-Idade
Neisseria mucosa/isolamento & purificação
Peptostreptococcus/isolamento & purificação
Propionibacterium acnes/isolamento & purificação
Aplainamento Radicular
Streptococcus mutans/isolamento & purificação
Streptococcus sobrinus/isolamento & purificação
Taq Polimerase
Raiz Dentária/microbiologia
Veillonella/isolamento & purificação
[Pt] Tipo de publicação:COMPARATIVE STUDY; JOURNAL ARTICLE; RANDOMIZED CONTROLLED TRIAL; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (Anti-Infective Agents, Local); 0 (DNA Probes); EC 2.7.7.- (Taq Polymerase); MOR84MUD8E (chlorhexidine gluconate); R4KO0DY52L (Chlorhexidine)
[Em] Mês de entrada:1201
[Cu] Atualização por classe:131121
[Lr] Data última revisão:
131121
[Sb] Subgrupo de revista:D
[Da] Data de entrada para processamento:110525
[St] Status:MEDLINE
[do] DOI:10.1111/j.1601-0825.2011.01815.x


  9 / 23 MEDLINE  
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[PMID]:21488936
[Au] Autor:Uzel NG; Teles FR; Teles RP; Song XQ; Torresyap G; Socransky SS; Haffajee AD
[Ad] Endereço:Department of Periodontology, The Forsyth Institute, Cambridge, MA 02142, USA.
[Ti] Título:Microbial shifts during dental biofilm re-development in the absence of oral hygiene in periodontal health and disease.
[So] Source:J Clin Periodontol;38(7):612-20, 2011 Jul.
[Is] ISSN:1600-051X
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:AIM: To monitor microbial shifts during dental biofilm re-development. MATERIALS AND METHODS: Supra- and subgingival plaque samples were taken separately from 28 teeth in 38 healthy and 17 periodontitis subjects at baseline and immediately after tooth cleaning. Samples were taken again from seven teeth in randomly selected quadrants during 1, 2, 4 and 7 days of no oral hygiene. Samples were analysed using checkerboard DNA-DNA hybridization. Species counts were averaged within subjects at each time point. Significant differences in the counts between healthy and periodontitis subjects were determined using the Mann-Whitney test. RESULTS: The total supra- and subgingival counts were significantly higher in periodontitis on entry and reached or exceeded the baseline values after day 2. Supragingival counts of Veillonella parvula, Fusobacterium nucleatum ss vincentii and Neisseria mucosa increased from 2 to 7 days. Subgingival counts were greater for Actinomyces, green and orange complex species. Significant differences between groups in supragingival counts occurred for 17 of 41 species at entry, 0 at day 7; for subgingival plaque, these values were 39/41 taxa at entry, 17/41 at day 7. CONCLUSIONS: Supragingival plaque re-development was similar in periodontitis and health, but subgingival species recolonization was more marked in periodontitis.
[Mh] Termos MeSH primário: Biofilmes/crescimento & desenvolvimento
Periodontite Crônica/microbiologia
Placa Dentária/microbiologia
Periodonto/microbiologia
[Mh] Termos MeSH secundário: Actinomyces/crescimento & desenvolvimento
Actinomyces/fisiologia
Adulto
Carga Bacteriana
Bacteroides/crescimento & desenvolvimento
Bacteroides/fisiologia
DNA Bacteriano/análise
Placa Dentária/terapia
Raspagem Dentária
Feminino
Fusobacterium nucleatum/crescimento & desenvolvimento
Fusobacterium nucleatum/fisiologia
Hemorragia Gengival/microbiologia
Gengivite/microbiologia
Seres Humanos
Masculino
Neisseria mucosa/crescimento & desenvolvimento
Neisseria mucosa/fisiologia
Hibridização de Ácido Nucleico
Higiene Bucal
Perda da Inserção Periodontal/microbiologia
Bolsa Periodontal/microbiologia
Porphyromonas gingivalis/crescimento & desenvolvimento
Porphyromonas gingivalis/fisiologia
Aplainamento Radicular
Treponema denticola/crescimento & desenvolvimento
Treponema denticola/fisiologia
Veillonella/crescimento & desenvolvimento
Veillonella/fisiologia
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, N.I.H., EXTRAMURAL
[Nm] Nome de substância:
0 (DNA, Bacterial)
[Em] Mês de entrada:1110
[Cu] Atualização por classe:161122
[Lr] Data última revisão:
161122
[Sb] Subgrupo de revista:D; IM
[Da] Data de entrada para processamento:110415
[St] Status:MEDLINE
[do] DOI:10.1111/j.1600-051X.2011.01730.x


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[PMID]:21354666
[Au] Autor:Durán E; Salvo S; Gil J; Sanjoaquín I
[Ti] Título:[Pneumonia and bacteremia due to Neisseria mucosa in a human immunodeficient virus seropositive patient parenteral drug abuser].
[Ti] Título:Neumonía y bacteriemia por Neisseria mucosa en un paciente usuario de drogas por vía parenteral infectado por el virus de la inmunodeficiencia humana tipo 1..
[So] Source:Enferm Infecc Microbiol Clin;29(3):236-7, 2011 Mar.
[Is] ISSN:1578-1852
[Cp] País de publicação:Spain
[La] Idioma:spa
[Mh] Termos MeSH primário: Bacteriemia/etiologia
Infecções por HIV/complicações
Neisseria mucosa/isolamento & purificação
Infecções por Neisseriaceae/diagnóstico
Pneumonia Bacteriana/etiologia
Abuso de Substâncias por Via Intravenosa/complicações
[Mh] Termos MeSH secundário: Adulto
Bacteriemia/microbiologia
Infecções por HIV/tratamento farmacológico
Implante de Prótese de Valva Cardíaca
Dependência de Heroína/complicações
Dependência de Heroína/tratamento farmacológico
Seres Humanos
Hospedeiro Imunocomprometido
Masculino
Metadona/uso terapêutico
Neisseria mucosa/patogenicidade
Infecções por Neisseriaceae/complicações
Infecções por Neisseriaceae/microbiologia
Marca-Passo Artificial
Pneumonia Bacteriana/microbiologia
Polimedicação
Complicações Pós-Operatórias/microbiologia
Fatores de Risco
[Pt] Tipo de publicação:CASE REPORTS; LETTER
[Nm] Nome de substância:
UC6VBE7V1Z (Methadone)
[Em] Mês de entrada:1107
[Cu] Atualização por classe:131121
[Lr] Data última revisão:
131121
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:110301
[St] Status:MEDLINE
[do] DOI:10.1016/j.eimc.2010.09.006



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