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[PMID]:28721843
[Au] Autor:Staton GJ; Newbrook K; Clegg SR; Birtles RJ; Evans NJ; Carter SD
[Ad] Endereço:1​Department of Infection Biology, Institute of Infection and Global Health, University of Liverpool, iC2 Building, Liverpool Science Park, Brownlow Hill, Liverpool, L3 5RF, UK.
[Ti] Título:Treponema rectale sp. nov., a spirochete isolated from the bovine rectum.
[So] Source:Int J Syst Evol Microbiol;67(7):2470-2475, 2017 Jul.
[Is] ISSN:1466-5034
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:A Gram-stain-negative, obligatory anaerobic spirochete, CHPAT, was isolated from the rectal tissue of a Holstein-Friesian cow. On the basis of 16S rRNA gene comparisons, CHPAT was most closely related to the human oral spirochete, Treponema parvum, with 88.8 % sequence identity. Further characterisation on the basis of recA gene sequence analysis, cell morphology, pattern of growth and physiological profiling identified marked differences with respect to other recognised species of the genus Treponema. Microscopically, the helical cells measured approximately 1-5 µm long and 0.15-0.25 µm wide, with two to five irregular spirals. Transmission electron microscopy identified four periplasmic flagella in a 2 : 4 : 2 arrangement. CHPAT grew independently of serum, demonstrated no evidence of haemolytic activity and possessed an in vitro enzyme activity profile that is unique amongst validly named species of the genus Treponema, exhibiting C4 esterase, α-galactosidase and ß-galactosidase activity. Taken together, these data indicate that CHPAT represents a novel species of the genus Treponema, for which the name Treponema rectale is proposed. The type strain of Treponema rectale is CHPAT (=DSM 103679T=NCTC 13848T).
[Mh] Termos MeSH primário: Bovinos/microbiologia
Filogenia
Reto/microbiologia
Treponema/classificação
[Mh] Termos MeSH secundário: Animais
Técnicas de Tipagem Bacteriana
DNA Bacteriano/genética
Esterases/genética
RNA Ribossômico 16S/genética
Análise de Sequência de DNA
Treponema/genética
Treponema/isolamento & purificação
Reino Unido
alfa-Galactosidase/genética
beta-Galactosidase/genética
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (DNA, Bacterial); 0 (RNA, Ribosomal, 16S); EC 3.1.- (Esterases); EC 3.2.1.22 (alpha-Galactosidase); EC 3.2.1.23 (beta-Galactosidase)
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170908
[Lr] Data última revisão:
170908
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170720
[St] Status:MEDLINE
[do] DOI:10.1099/ijsem.0.002051


  2 / 1415 MEDLINE  
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[PMID]:28542573
[Au] Autor:Anklam K; Kulow M; Yamazaki W; Döpfer D
[Ad] Endereço:Department of Medical Science, School of Veterinary Medicine, University of Wisconsin, Madison, Wisconsin, United States of America.
[Ti] Título:Development of real-time PCR and loop-mediated isothermal amplification (LAMP) assays for the differential detection of digital dermatitis associated treponemes.
[So] Source:PLoS One;12(5):e0178349, 2017.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Bovine digital dermatitis (DD) is a severe infectious cause of lameness in cattle worldwide, with important economic and welfare consequences. There are three treponeme phylogroups (T. pedis, T. phagedenis, and T. medium) that are implicated in playing an important causative role in DD. This study was conducted to develop real-time PCR and loop-mediated isothermal amplification (LAMP) assays for the detection and differentiation of the three treponeme phylogroups associated with DD. The real-time PCR treponeme phylogroup assays targeted the 16S-23S rDNA intergenic space (ITS) for T. pedis and T. phagedenis, and the flagellin gene (flaB2) for T. medium. The 3 treponeme phylogroup LAMP assays targeted the flagellin gene (flaB2) and the 16S rRNA was targeted for the Treponeme ssp. LAMP assay. The real-time PCR and LAMP assays correctly detected the target sequence of all control strains examined, and no cross-reactions were observed, representing 100% specificity. The limit of detection for each of the three treponeme phylogroup real-time PCR and LAMP assays was ≤ 70 fg/µl. The detection limit for the Treponema spp. LAMP assay ranged from 7-690 fg/µl depending on phylogroup. Treponemes were isolated from 40 DD lesion biopsies using an immunomagnetic separation culture method. The treponeme isolation samples were then subjected to the real-time PCR and LAMP assays for analysis. The treponeme phylogroup real-time PCR and LAMP assay results had 100% agreement, matching on all isolation samples. These results indicate that the developed assays are a sensitive and specific test for the detection and differentiation of the three main treponeme phylogroups implicated in DD.
[Mh] Termos MeSH primário: Doenças dos Bovinos/diagnóstico
Dermatite Digital/diagnóstico
Técnicas de Amplificação de Ácido Nucleico/métodos
Reação em Cadeia da Polimerase em Tempo Real/métodos
Treponema/genética
Infecções por Treponema/veterinária
[Mh] Termos MeSH secundário: Animais
Bovinos
Doenças dos Bovinos/microbiologia
Dermatite Digital/microbiologia
Seres Humanos
Limite de Detecção
Técnicas de Amplificação de Ácido Nucleico/veterinária
Filogenia
Reação em Cadeia da Polimerase em Tempo Real/veterinária
Sensibilidade e Especificidade
Infecções por Treponema/diagnóstico
Infecções por Treponema/microbiologia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170919
[Lr] Data última revisão:
170919
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170526
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0178349


  3 / 1415 MEDLINE  
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[PMID]:28113049
[Au] Autor:Newbrook K; Staton GJ; Clegg SR; Birtles RJ; Carter SD; Evans NJ
[Ad] Endereço:1​Department of Infection Biology, Institute of Infection and Global Health, University of Liverpool, Liverpool Science Park Innovation Centre 2, 146 Brownlow Hill, Liverpool, UK.
[Ti] Título:Treponema ruminis sp. nov., a spirochaete isolated from the bovine rumen.
[So] Source:Int J Syst Evol Microbiol;67(5):1349-1354, 2017 May.
[Is] ISSN:1466-5034
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:A novel bacterium, strain Ru1T, was encountered during a survey of spirochaetes living in the gastrointestinal tract of ruminants. Comparative analysis of 16S rRNA gene sequence data indicated that strain Ru1T clustered within the genus Treponemabut shared at most 86.1 % sequence similarity with other recognised species of the genus Treponema. Further phylogenetic analysis based on partial recombinase A (recA) gene sequence comparisons, together with phenotypic characterization, also demonstrated the divergence of strain Ru1T from other recognised species of the genus Treponema. Microscopically, strain Ru1T appeared as a very small, highly motile, helical spirochaete with eight periplasmic flagella in a 4 : 8 : 4 arrangement. It exhibited C8 esterase lipase, leucine arylamidase, ß-galactosidase and ß-glucosidase activity. A distinctive, serum-independent growth pattern was also observed, characterized by colonies with an absence of the local haemolysis that is typical of many pathogenic treponemes. On the basis of these data, strain Ru1T is considered to represent a novel species of the genus Treponema, for which the name Treponema ruminis sp. nov. is proposed. The type strain is Ru1T (=DSM 103462T=NCTC 13847T).
[Mh] Termos MeSH primário: Bovinos/microbiologia
Filogenia
Rúmen/microbiologia
Treponema/classificação
[Mh] Termos MeSH secundário: Animais
Técnicas de Tipagem Bacteriana
Composição de Bases
DNA Bacteriano/genética
Masculino
RNA Ribossômico 16S/genética
Análise de Sequência de DNA
Treponema/genética
Treponema/isolamento & purificação
Reino Unido
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (DNA, Bacterial); 0 (RNA, Ribosomal, 16S)
[Em] Mês de entrada:1708
[Cu] Atualização por classe:170825
[Lr] Data última revisão:
170825
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170124
[St] Status:MEDLINE
[do] DOI:10.1099/ijsem.0.001812


  4 / 1415 MEDLINE  
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[PMID]:27856942
[Au] Autor:Borsanelli AC; Ramos TN; Gaetti-Jardim E; Schweitzer CM; Dutra IS
[Ad] Endereço:Postgraduate Program in Veterinary Medicine, Faculty of Agricultural and Veterinary Sciences of Jaboticabal, UNESP Univ Estadual Paulista, Via de Acesso Prof. Paulo Donato Castellane s/n, Jaboticabal, SP 14884-900, Brazil.
[Ti] Título: species in the subgingival microflora of ovine periodontitis.
[So] Source:Vet Rec;180(6):150, 2017 Feb 11.
[Is] ISSN:2042-7670
[Cp] País de publicação:England
[La] Idioma:eng
[Mh] Termos MeSH primário: Gengiva/microbiologia
Periodontite/veterinária
Doenças dos Ovinos/microbiologia
Treponema/isolamento & purificação
[Mh] Termos MeSH secundário: Animais
Periodontite/microbiologia
Reação em Cadeia da Polimerase/veterinária
Ovinos
Treponema/genética
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1706
[Cu] Atualização por classe:170626
[Lr] Data última revisão:
170626
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161119
[St] Status:MEDLINE
[do] DOI:10.1136/vr.103946


  5 / 1415 MEDLINE  
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[PMID]:27684969
[Au] Autor:Ruiz SJ; Procop GW
[Ad] Endereço:Robert J. Tomsich Pathology and Laboratory Medicine Institute, Cleveland Clinic, Cleveland, Ohio.
[Ti] Título:Cross-reactivity of Anti-Treponema Immunohistochemistry With Non-Treponema Spirochetes: A Simple Call for Caution.
[So] Source:Arch Pathol Lab Med;140(10):1021-2, 2016 Oct.
[Is] ISSN:1543-2165
[Cp] País de publicação:United States
[La] Idioma:eng
[Mh] Termos MeSH primário: Anticorpos Antibacterianos/imunologia
Anticorpos Monoclonais/imunologia
Reações Cruzadas/imunologia
Imuno-Histoquímica/métodos
Spirochaetales/imunologia
Treponema/imunologia
[Mh] Termos MeSH secundário: Diagnóstico Diferencial
Erros de Diagnóstico/prevenção & controle
Seres Humanos
Enteropatias/diagnóstico
Enteropatias/imunologia
Enteropatias/microbiologia
Reprodutibilidade dos Testes
Sensibilidade e Especificidade
Infecções por Spirochaetales/diagnóstico
Infecções por Spirochaetales/imunologia
Infecções por Spirochaetales/microbiologia
Sífilis/diagnóstico
Sífilis/imunologia
Sífilis/microbiologia
Treponema pallidum/imunologia
Treponema pallidum/fisiologia
[Pt] Tipo de publicação:LETTER
[Nm] Nome de substância:
0 (Antibodies, Bacterial); 0 (Antibodies, Monoclonal)
[Em] Mês de entrada:1702
[Cu] Atualização por classe:170817
[Lr] Data última revisão:
170817
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:160930
[St] Status:MEDLINE
[do] DOI:10.5858/arpa.2016-0004-LE


  6 / 1415 MEDLINE  
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[PMID]:27488881
[Au] Autor:Knauf S; Raphael J; Mitjà O; Lejora IAV; Chuma IS; Batamuzi EK; Keyyu JD; Fyumagwa R; Lüert S; Godornes C; Liu H; Schwarz C; Smajs D; Grange P; Zinner D; Roos C; Lukehart SA
[Ad] Endereço:Work Group Neglected Tropical Diseases, Pathology Unit, German Primate Center, Leibniz Institute for Primate Research, Kellnerweg 4, 37077 Göttingen, Germany. Electronic address: sknauf@dpz.eu.
[Ti] Título:Isolation of Treponema DNA from Necrophagous Flies in a Natural Ecosystem.
[So] Source:EBioMedicine;11:85-90, 2016 Sep.
[Is] ISSN:2352-3964
[Cp] País de publicação:Netherlands
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Recently, the World Health Organization launched a campaign to eradicate the tropical disease yaws, caused by the bacterium Treponema pallidum subsp. pertenue; however, for decades researchers have questioned whether flies act as a vector for the pathogen that could facilitate transmission. METHODS: A total of 207 fly specimens were trapped in areas of Africa in which T. pallidum-induced skin ulcerations are common in wild baboons; 88 flies from Tarangire National Park and 119 from Lake Manyara National Park in Tanzania were analyzed by PCR for the presence of T. pallidum DNA. FINDINGS: We report that in the two study areas, T. pallidum DNA was found in 17-24% of wild-caught flies of the order Diptera. Treponemal DNA sequences obtained from many of the flies match sequences derived from nearby baboon T. pallidum strains, and one of the fly species with an especially high prevalence of T. pallidum DNA, Musca sorbens, has previously been shown to transmit yaws in an experimental setting. INTERPRETATION: Our results raise the possibility that flies play a role in yaws transmission; further research is warranted, given how important understanding transmission is for the eradication of this disfiguring disease.
[Mh] Termos MeSH primário: DNA Bacteriano
Dípteros/microbiologia
Ecossistema
Treponema/genética
[Mh] Termos MeSH secundário: África
Animais
Dípteros/classificação
Microbiologia Ambiental
Genes Bacterianos
Insetos Vetores/microbiologia
Papio/microbiologia
Filogenia
Análise de Sequência de DNA
Tanzânia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (DNA, Bacterial)
[Em] Mês de entrada:1702
[Cu] Atualização por classe:171106
[Lr] Data última revisão:
171106
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160805
[St] Status:MEDLINE


  7 / 1415 MEDLINE  
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[PMID]:27317761
[Au] Autor:Maboni G; Frosth S; Aspán A; Tötemeyer S
[Ad] Endereço:School of Veterinary Medicine and Science, University of Nottingham, Sutton Bonington, UK.
[Ti] Título:Ovine footrot: new insights into bacterial colonisation.
[So] Source:Vet Rec;179(9):228, 2016 Sep 03.
[Is] ISSN:2042-7670
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Ovine footrot is characterised by interdigital dermatitis (ID) and by the separation of the skin and hoof horn (under-running footrot). Dichelobacter nodosus is the essential pathogen causing footrot; the role of other microorganisms in this disease remains unclear. The aims of this study were (i) to investigate the colonisation of D nodosus, Fusobacterium necrophorum and Treponema species in biopsies from the ovine interdigital skin of healthy, ID and footrot-affected feet and (ii) to characterise the virulence of D nodosus strains in those biopsies. Postslaughter biopsy samples (n=241) were collected and analysed by real-time PCR to determine prevalence and load of the different bacterial species. The highest prevalence and load of D nodosus were found on feet with ID. The vast majority of samples contained virulent D nodosus and some samples contained both virulent and benign D nodosus Notably, the more pathogenic subspecies of F necrophorum was found in samples from UK sheep. Our findings provide further insights into the role bacterial colonisation may play in the early stage of ID and in the progression towards footrot.
[Mh] Termos MeSH primário: Pododermatite Necrótica dos Ovinos/microbiologia
Doenças dos Ovinos/microbiologia
[Mh] Termos MeSH secundário: Animais
Dichelobacter nodosus/isolamento & purificação
Dichelobacter nodosus/patogenicidade
Fusobacterium necrophorum/isolamento & purificação
Fusobacterium necrophorum/patogenicidade
Ovinos
Treponema/isolamento & purificação
Treponema/patogenicidade
Virulência
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1705
[Cu] Atualização por classe:170817
[Lr] Data última revisão:
170817
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160619
[St] Status:MEDLINE
[do] DOI:10.1136/vr.103610


  8 / 1415 MEDLINE  
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[PMID]:27289055
[Au] Autor:Jiang X; Shen J; Lou S; Mu Y; Wang N; Han W; Sun X; Li J; Wang L
[Ad] Endereço:Jiangsu Key Laboratory of Chemical Pollution Control and Resources Reuse, School of Environmental and Biological Engineering, Nanjing University of Science and Technology, Nanjing 210094, Jiangsu Province, China.
[Ti] Título:Comprehensive comparison of bacterial communities in a membrane-free bioelectrochemical system for removing different mononitrophenols from wastewater.
[So] Source:Bioresour Technol;216:645-52, 2016 Sep.
[Is] ISSN:1873-2976
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Membrane-free bioelectrochemical systems (MFBESs) have been developed for the degradation of nitro-aromatic contaminants, but the microbial communities that are involved have not been comprehensively investigated. In this study, the microbial communities were evaluated and compared for treating different structures of nitrophenols (NPs), i.e., o-nitrophenol (ONP), m-nitrophenol (MNP) and p-nitrophenol (PNP), in the MFBES. The results demonstrated that NPs reduction in the MFBES decreased in efficiency in the following order: ONP>MNP>PNP. Illumina MiSeq sequencing results showed that richness and diversity of bacterial species in the anodic and cathodic communities decreased when fed different NPs. Though remarkable differences in community composition were found between anodic and cathodic biofilms in the MFBES, three core genera-Treponema, Desulfovibrio and Geobacter-were dominant in the anodic or cathodic biofilm, regardless of various NPs. Other functional genera in the anodic or cathodic biofilm were selectively enriched in the MFBES treating the three NPs with different structures.
[Mh] Termos MeSH primário: Biofilmes
Nitrofenóis/isolamento & purificação
Águas Residuais/química
Purificação da Água
[Mh] Termos MeSH secundário: Fontes de Energia Bioelétrica/microbiologia
Reatores Biológicos
Desulfovibrio/genética
Técnicas Eletroquímicas
Geobacter/genética
Consórcios Microbianos/genética
Tipagem Molecular
Nitrofenóis/química
RNA Bacteriano/genética
RNA Ribossômico 16S/genética
Análise de Sequência de RNA
Esgotos/microbiologia
Treponema/genética
Águas Residuais/análise
[Pt] Tipo de publicação:COMPARATIVE STUDY; JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Nitrophenols); 0 (RNA, Bacterial); 0 (RNA, Ribosomal, 16S); 0 (Sewage); 0 (Waste Water)
[Em] Mês de entrada:1701
[Cu] Atualização por classe:170125
[Lr] Data última revisão:
170125
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160612
[St] Status:MEDLINE


  9 / 1415 MEDLINE  
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[PMID]:27259832
[Au] Autor:Mushtaq M; Bongcam-Rudloff E; Loftsdottir H; Pringle M; Segerman B; Zuerner R; Rosander A
[Ad] Endereço:Department of Animal Breeding and Genetics Science, Swedish University of Agricultural Science, SLU-Global Bioinformatics Centre, Uppsala, SE 750 07, Sweden; Department of Bioinformatics and Biotechnology, International Islamic University, Islamabad, Pakistan. Electronic address: mamoona.mushtaq@iiu
[Ti] Título:Genetic analysis of a Treponema phagedenis locus encoding antigenic lipoproteins with potential for antigenic variation.
[So] Source:Vet Microbiol;189:91-8, 2016 Jun 30.
[Is] ISSN:1873-2542
[Cp] País de publicação:Netherlands
[La] Idioma:eng
[Ab] Resumo:Digital dermatitis (DD) is a painful and debilitating claw disease in cattle. Spirochetes of the genus Treponema are found in high numbers in the lesions and are likely to be involved in the pathogenesis. The occurrence of Treponema phagedenis in DD lesions, especially near the interface of healthy and diseased tissue, suggests that this species contributes to the development and/or progression of the lesions. In this study we characterized a genetic locus in T. phagedenis that contains coding regions for three antigenic proteins, PrrA, VpsA, and VpsB. Comparative analysis of homologous loci from fifteen strains suggests that prrA may be transposed into or out of this locus. Alterations in the copy number of TA repeats within the putative promoter region may regulate VpsA/B expression. The vpsA and prrA genes occur in allelic variants in different T. phagedenis isolates and may provide one explanation for the antigenic variation observed in T. phagedenis DD isolates.
[Mh] Termos MeSH primário: Variação Antigênica/genética
Antígenos de Bactérias/genética
Lipoproteínas/genética
Treponema/genética
[Mh] Termos MeSH secundário: Alelos
Sequência de Aminoácidos
Animais
Dermatite Digital/microbiologia
Regulação Bacteriana da Expressão Gênica
Alinhamento de Sequência
Treponema/patogenicidade
Infecções por Treponema/microbiologia
Infecções por Treponema/veterinária
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Antigens, Bacterial); 0 (Lipoproteins)
[Em] Mês de entrada:1612
[Cu] Atualização por classe:161230
[Lr] Data última revisão:
161230
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160605
[St] Status:MEDLINE


  10 / 1415 MEDLINE  
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[PMID]:27208135
[Au] Autor:Clegg SR; Carter SD; Birtles RJ; Brown JM; Hart CA; Evans NJ
[Ad] Endereço:Department of Infection Biology, Institute of Infection and Global Health, School of Veterinary Science, University of Liverpool, Liverpool, United Kingdom s.r.clegg@liverpool.ac.uk.
[Ti] Título:Multilocus Sequence Typing of Pathogenic Treponemes Isolated from Cloven-Hoofed Animals and Comparison to Treponemes Isolated from Humans.
[So] Source:Appl Environ Microbiol;82(15):4523-36, 2016 Aug 01.
[Is] ISSN:1098-5336
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:UNLABELLED: Treponema species are implicated in many diseases of humans and animals. Digital dermatitis (DD) treponemes are reported to cause severe lesions in cattle, sheep, pigs, goats, and wild elk, causing substantial global animal welfare issues and economic losses. The fastidiousness of these spirochetes has previously precluded studies investigating within-phylogroup genetic diversity. An archive of treponemes that we isolated enabled multilocus sequence typing to quantify the diversity and population structure of DD treponemes. Isolates (n = 121) were obtained from different animal hosts in nine countries on three continents. The analyses herein of currently isolated DD treponemes at seven housekeeping gene loci confirm the classification of the three previously designated phylogroups: the Treponema medium, Treponema phagedenis, and Treponema pedis phylogroups. Sequence analysis of seven DD treponeme housekeeping genes revealed a generally low level of diversity among the strains within each phylogroup, removing the need for the previously used "-like" suffix. Surprisingly, all isolates within each phylogroup clustered together, regardless of host or geographic origin, suggesting that the same sequence types (STs) can infect different animals. Some STs were derived from multiple animals from the same farm, highlighting probable within-farm transmissions. Several STs infected multiple hosts from similar geographic regions, identifying probable frequent between-host transmissions. Interestingly, T. pedis appears to be evolving more quickly than the T. medium or T. phagedenis DD treponeme phylogroup, by forming two unique ST complexes. The lack of phylogenetic discrimination between treponemes isolated from different hosts or geographic regions substantially contrasts with the data for other clinically relevant spirochetes. IMPORTANCE: The recent expansion of the host range of digital dermatitis (DD) treponemes from cattle to sheep, goats, pigs, and wild elk, coupled with the high level of 16S rRNA gene sequence similarity across hosts and with human treponemes, suggests that the same bacterial species can cause disease in multiple different hosts. This multilocus sequence typing (MLST) study further demonstrates that these bacteria isolated from different hosts are indeed very similar, raising the potential for cross-species transmission. The study also shows that infection spread occurs frequently, both locally and globally, suggesting transmission by routes other than animal-animal transmission alone. These results indicate that on-farm biosecurity is important for controlling disease spread in domesticated species. Continued surveillance and vigilance are important for ascertaining the evolution and tracking any further host range expansion of these important pathogens.
[Mh] Termos MeSH primário: Treponema/isolamento & purificação
Infecções por Treponema/microbiologia
Infecções por Treponema/veterinária
[Mh] Termos MeSH secundário: Animais
Bovinos
Doenças dos Bovinos/microbiologia
Cervos
Doenças das Cabras/microbiologia
Cabras
Seres Humanos
Tipagem de Sequências Multilocus
Filogenia
Ovinos
Doenças dos Ovinos/microbiologia
Suínos
Doenças dos Suínos/microbiologia
Treponema/classificação
Treponema/genética
[Pt] Tipo de publicação:COMPARATIVE STUDY; JOURNAL ARTICLE
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170922
[Lr] Data última revisão:
170922
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160522
[St] Status:MEDLINE
[do] DOI:10.1128/AEM.00025-16



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