Base de dados : MEDLINE
Pesquisa : B03.440.450.690.590 [Categoria DeCS]
Referências encontradas : 247 [refinar]
Mostrando: 1 .. 10   no formato [Detalhado]

página 1 de 25 ir para página                         

  1 / 247 MEDLINE  
              next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:28781236
[Au] Autor:Pausch P; Müller-Esparza H; Gleditzsch D; Altegoer F; Randau L; Bange G
[Ad] Endereço:LOEWE Center for Synthetic Microbiology (Synmikro) and Faculty of Chemistry, Philipps-University-Marburg, Hans-Meerwein-Strasse C07, 35043 Marburg, Germany.
[Ti] Título:Structural Variation of Type I-F CRISPR RNA Guided DNA Surveillance.
[So] Source:Mol Cell;67(4):622-632.e4, 2017 Aug 17.
[Is] ISSN:1097-4164
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:CRISPR-Cas systems are prokaryotic immune systems against invading nucleic acids. Type I CRISPR-Cas systems employ highly diverse, multi-subunit surveillance Cascade complexes that facilitate duplex formation between crRNA and complementary target DNA for R-loop formation, retention, and DNA degradation by the subsequently recruited nuclease Cas3. Typically, the large subunit recognizes bona fide targets through the PAM (protospacer adjacent motif), and the small subunit guides the non-target DNA strand. Here, we present the Apo- and target-DNA-bound structures of the I-Fv (type I-F variant) Cascade lacking the small and large subunits. Large and small subunits are functionally replaced by the 5' terminal crRNA cap Cas5fv and the backbone protein Cas7fv, respectively. Cas5fv facilitates PAM recognition from the DNA major groove site, in contrast to all other described type I systems. Comparison of the type I-Fv Cascade with an anti-CRISPR protein-bound I-F Cascade reveals that the type I-Fv structure differs substantially at known anti-CRISPR protein target sites and might therefore be resistant to viral Cascade interception.
[Mh] Termos MeSH primário: Proteínas de Bactérias/metabolismo
Proteínas Associadas a CRISPR/metabolismo
Sistemas CRISPR-Cas
Repetições Palindrômicas Curtas Agrupadas e Regularmente Espaçadas
DNA/metabolismo
Endonucleases/metabolismo
Ácidos Nucleicos Heteroduplexes/metabolismo
RNA Guia/metabolismo
[Mh] Termos MeSH secundário: Proteínas de Bactérias/química
Proteínas de Bactérias/genética
Sítios de Ligação
Proteínas Associadas a CRISPR/química
Proteínas Associadas a CRISPR/genética
Cristalografia por Raios X
DNA/química
DNA/genética
Endonucleases/química
Endonucleases/genética
Escherichia coli/enzimologia
Escherichia coli/genética
Modelos Moleculares
Conformação de Ácido Nucleico
Ácidos Nucleicos Heteroduplexes/química
Ácidos Nucleicos Heteroduplexes/genética
Ligação Proteica
Conformação Proteica
Capuzes de RNA/metabolismo
RNA Guia/química
RNA Guia/genética
Shewanella putrefaciens/enzimologia
Shewanella putrefaciens/genética
Relação Estrutura-Atividade
[Pt] Tipo de publicação:COMPARATIVE STUDY; JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Bacterial Proteins); 0 (CRISPR-Associated Proteins); 0 (Nucleic Acid Heteroduplexes); 0 (RNA Caps); 0 (RNA, Guide); 9007-49-2 (DNA); EC 3.1.- (Endonucleases)
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170925
[Lr] Data última revisão:
170925
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170808
[St] Status:MEDLINE


  2 / 247 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:28545603
[Au] Autor:Ghorbanzadeh N; Lakzian A; Halajnia A; Choi UK; Kim KH; Kim JO; Kurade M; Jeon BH
[Ti] Título:Impact of Bioreduction on Remobilization of Adsorbed Cadmium on Iron Minerals in Anoxic Condition.
[So] Source:Water Environ Res;89(6):519-526, 2017 Jun 01.
[Is] ISSN:1061-4303
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:The impact of bioreduction on the remobilization of adsorbed cadmium Cd(II) on minerals, including hematite, goethite, and two iron(III)-rich clay minerals nontronites (NAU-1 and NAU-2) under anoxic conditions was investigated. Langmuir isotherm equation better described the sorption of Cd(II) onto the all minerals. The maximum adsorption capacity was 6.2, 18.1, 3.6, and 4 mg g-1 for hematite, goethite, NAU-1 and NAU-2, respectively. The desorption of Cd(II) was due to the production of Fe(II) as a result of bioreduction of structural Fe(III) in the minerals by Shewanella putrefaciens. The bioreduction of Cd(II)-loaded Fe(III) minerals was negligible during the initial 5 days followed by a rapid increase up to 20 days. The amount of Cd(II) in solution phase at the end of 30 days increased up to 0.07 mmol L-1 for hematite, NAU-1, and NAU-2 and 0.02 mmol L-1 for goethite. The X-ray diffraction study showed negligible changes in bioreduced minerals phases.
[Mh] Termos MeSH primário: Cádmio/química
Compostos Férricos/química
Shewanella putrefaciens/metabolismo
[Mh] Termos MeSH secundário: Adsorção
Silicatos de Alumínio/química
Biodegradação Ambiental
Minerais/química
Oxigênio
Difração de Raios X
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Aluminum Silicates); 0 (Ferric Compounds); 0 (Minerals); 00BH33GNGH (Cadmium); 1302-87-0 (clay); 1K09F3G675 (ferric oxide); S88TT14065 (Oxygen)
[Em] Mês de entrada:1707
[Cu] Atualização por classe:170726
[Lr] Data última revisão:
170726
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170527
[St] Status:MEDLINE
[do] DOI:10.2175/106143017X14902968254449


  3 / 247 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:28290573
[Au] Autor:Wang L; Xu S; Pan B; Yang Y
[Ad] Endereço:Department of Civil and Environmental Engineering, University of Nevada, Reno, NV 89557, USA. yuy@unr.edu.
[Ti] Título:Emerging investigator series: dual role of organic matter in the anaerobic degradation of triclosan.
[So] Source:Environ Sci Process Impacts;19(4):499-506, 2017 Apr 19.
[Is] ISSN:2050-7895
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Triclosan (TCS), one of the most widely used antimicrobial agents, has been listed among the top 10 contaminants in US rivers. Environmental persistence, endocrine disruption effects, and the antibiotic resistance induction capacity of TCS attract interest in its environmental fate and degradation. Herein, we found that TCS can be anaerobically degraded at pH 9 by a metal-reducing bacterium, Shewanella putrefaciens CN32. The degradation was substantially facilitated by low-concentration (0-15 mg C per L) organic matter (OM) extracted from a peat soil, whereas TCS degradation was inhibited by further increased concentration (15-100 mg C per L) of OM. OM acted as both an electron shuttle and sorbent in regulating the degradation of TCS. The novel dual role of ubiquitous OM in the reaction of TCS governs the environmental degradation and persistence of TCS. Our study highlights the effects of OM on the reaction of emerging trace organic pollutants, with implications on their engineering treatment and environmental risk regulation.
[Mh] Termos MeSH primário: Biodegradação Ambiental
Recuperação e Remediação Ambiental/métodos
Shewanella putrefaciens/metabolismo
Triclosan/química
Triclosan/metabolismo
Poluentes Químicos da Água/química
Poluentes Químicos da Água/metabolismo
[Mh] Termos MeSH secundário: Anaerobiose
Monitoramento Ambiental
Pesquisadores
Estados Unidos
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Water Pollutants, Chemical); 4NM5039Y5X (Triclosan)
[Em] Mês de entrada:1705
[Cu] Atualização por classe:170530
[Lr] Data última revisão:
170530
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170315
[St] Status:MEDLINE
[do] DOI:10.1039/c7em00003k


  4 / 247 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:28183187
[Au] Autor:Dai Y; Sun T; Zhang Z; Zhang ZJ; Li JR
[Ad] Endereço:College of Food Science and Project Engineering, Bohai University, Food Safety Key Lab of Liaoning Province, National and Local Joint Engineering Research Center of Storage, Processing and Safety Control Technology for Fresh Agricultural and Aquatic Products, Jinzhou, Liaoning 121013, China.
[Ti] Título:Effect of zinc oxide film morphologies on the formation of Shewanella putrefaciens biofilm.
[So] Source:Biointerphases;12(1):011002, 2017 Feb 09.
[Is] ISSN:1559-4106
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Zinc oxide (ZnO) films were prepared on aluminum substrate by a hydrothermal method to investigate the effect of their surface characteristics, including morphology and hydrophobicity, on the corresponding antibiofilm performance. The surface characteristics of the prepared ZnO films were examined by a comprehensive range of methodologies, suggesting that films of distinctive surface morphologies were successfully formed. Subsequently, their antibiofilm activities, using Shewanella putrefaciens as a model bacterium, were assessed. Surface measurements confirmed that the ZnO films equipped with a nanoscopic needlelike surface feature are more hydrophobic than those possessing densely packed microflakes. The reduced number of live cells and presence of biofilm, confirmed by optical and electron microscopy results, suggest that the former films possess an excellent antibiofilm performance. It is believed that the engineered nanoscopic needle feature might penetrate the cell membrane when they are in contact, allowing the effective substance of ZnO antibacterial ingredients to diffuse into the embedded bacteria. Furthermore, such surface characteristics might perturb the integrity of the cell membrane causing the intracellular substance is leaked from the cells. As such, the combinatorial effects of nanoscopic feature resulted in an inhibited growth of S. putrefaciens biofilm on ZnO film.
[Mh] Termos MeSH primário: Antibacterianos/farmacologia
Biofilmes/efeitos dos fármacos
Biofilmes/crescimento & desenvolvimento
Shewanella putrefaciens/efeitos dos fármacos
Shewanella putrefaciens/fisiologia
Propriedades de Superfície
Óxido de Zinco/farmacologia
[Mh] Termos MeSH secundário: Microscopia
Nanoestruturas
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Anti-Bacterial Agents); SOI2LOH54Z (Zinc Oxide)
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170913
[Lr] Data última revisão:
170913
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170211
[St] Status:MEDLINE
[do] DOI:10.1116/1.4976003


  5 / 247 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:28110139
[Au] Autor:Yang L; Deng W; Zhang Y; Tan Y; Ma M; Xie Q
[Ad] Endereço:Key Laboratory of Chemical Biology and Traditional Chinese Medicine Research (Ministry of Education of China), College of Chemistry and Chemical Engineering, Hunan Normal University, Changsha 410081, China.
[Ti] Título:Boosting current generation in microbial fuel cells by an order of magnitude by coating an ionic liquid polymer on carbon anodes.
[So] Source:Biosens Bioelectron;91:644-649, 2017 May 15.
[Is] ISSN:1873-4235
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Microbial fuel cells (MFCs) have attracted great attentions due to their great application potentials, but the relatively low power densities of MFCs still hinder their widespread practical applications. Herein, we report that the current generation in MFCs can be boosted by an order of magnitude, simply by coating a hydrophilic and positively charged ionic liquid polymer (ILP) on carbon cloth (CC) or carbon felt (CF). The ILP coating not only can increase the bacterial loading capacity due to the electrostatic interactions between ILP and bacterial cells, but also can improve the mediated extracellular electron transfer between the electrode and the cytochrome proteins on the outer membrane of Shewanella putrefaciens cells. As a result, the maximum power density of a MFC equipped with the CF-ILP bioanode is as high as 4400±170mWm , which is amongst the highest values reported to date. This work demonstrates a new strategy for greatly boosting the current generation in MFCs.
[Mh] Termos MeSH primário: Fontes de Energia Bioelétrica/microbiologia
Biofilmes
Líquidos Iônicos/química
Polímeros/química
Shewanella putrefaciens/fisiologia
[Mh] Termos MeSH secundário: Biofilmes/crescimento & desenvolvimento
Carbono/química
Eletricidade
Eletrodos
Transporte de Elétrons
Propriedades de Superfície
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Ionic Liquids); 0 (Polymers); 7440-44-0 (Carbon)
[Em] Mês de entrada:1703
[Cu] Atualização por classe:170531
[Lr] Data última revisão:
170531
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170123
[St] Status:MEDLINE


  6 / 247 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:28089892
[Au] Autor:Soltani EK; Cerezuela R; Charef N; Mezaache-Aichour S; Esteban MA; Zerroug MM
[Ad] Endereço:Laboratory of Applied Biochemistry, Faculty of Natural and Life Sciences, University Ferhat Abbas Sétif 1, Algeria.
[Ti] Título:Algerian propolis extracts: Chemical composition, bactericidal activity and in vitro effects on gilthead seabream innate immune responses.
[So] Source:Fish Shellfish Immunol;62:57-67, 2017 Mar.
[Is] ISSN:1095-9947
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Propolis has been used as a medicinal agent for centuries. The chemical composition of four propolis samples collected from four locations of the Sétif region, Algeria, using gas chromatography-mass spectrometry was determined. More than 20 compounds and from 30 to 35 compounds were identified in the aqueous and ethanolic extracts, respectively. Furthermore, the antimicrobial activity of the propolis extracts against two marine pathogenic bacteria was evaluated. Finally, the in vitro effects of propolis on gilthead seabream (Sparus aurata L.) leucocyte activities were measured. The bactericidal activity of ethanolic extracts was very high against Shewanella putrefaciens, average against Photobacterium damselae and very low against Vibrio harveyi. The lowest bactericidal activity was always that found for the aqueous extracts. When the viability of gilthead seabream head-kidney leucocytes was measured after 30 min' incubation with the different extracts, both the ethanolic and aqueous extracts of one of the propolis samples (from Babor) and the aqueous extract of another (from Ain-Abbassa) provoked a significant decrease in cell viability when used at concentrations of 100 and 200 µg ml . Furthermore, significant inhibitory effects were recorded on leucocyte respiratory burst activity when isolated leucocytes where preincubated with the extracts. This effect was dose-dependent in all cases except when extracts from a third propolis sample (from Boutaleb) were used. Our findings suggest that some of Algerian propolis extracts have bactericidal activity against important bacterial pathogens in seabream and significantly modulate in vitro leucocyte activities, confirming their potential as a source of new natural biocides and/or immunomodulators in aquaculture practice.
[Mh] Termos MeSH primário: Adjuvantes Imunológicos/farmacologia
Imunidade Inata/efeitos dos fármacos
Photobacterium/efeitos dos fármacos
Própole/farmacologia
Dourada/imunologia
Shewanella putrefaciens/efeitos dos fármacos
Vibrio/efeitos dos fármacos
[Mh] Termos MeSH secundário: Adjuvantes Imunológicos/química
Argélia
Animais
Cromatografia Gasosa-Espectrometria de Massas/veterinária
Leucócitos/efeitos dos fármacos
Própole/química
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Adjuvants, Immunologic); 9009-62-5 (Propolis)
[Em] Mês de entrada:1704
[Cu] Atualização por classe:170410
[Lr] Data última revisão:
170410
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170117
[St] Status:MEDLINE


  7 / 247 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:27982438
[Au] Autor:Esteve C; Merchán R; Alcaide E
[Ad] Endereço:Departamento de Microbiología y Ecología, Universitat de València, Valencia, Spain.
[Ti] Título:An outbreak of Shewanella putrefaciens group in wild eels Anguilla anguilla L. favoured by hypoxic aquatic environments.
[So] Source:J Fish Dis;40(7):929-939, 2017 Jul.
[Is] ISSN:1365-2761
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Microbiological analyses were conducted on wild eels from the L'Albufera Lake (Spain). A total of 174 individuals were collected in two surveys (i.e. year 2008 and autumn-winter 2014) among those caught by local fishermen into the lagoon. The prevalence of Shewanella putrefaciens group was 1.7% in 2008 and rose above 32% in 2014. It was due to an outbreak of shewanellosis that presented a morbidity rate of 64%. S. putrefaciens group strains were isolated as pure cultures from the sick eels that showed white ulcers surrounded by a reddish inflammation, damage of the mouth, extensive skin discoloration, exophthalmia, ascites and bad odour. The S. putrefaciens group was recovered from freshwater samples taken at the L'Albufera system, along autumn-winter 2015. Its counts significantly increased in freshwater parallel to hypoxia and temperature rising. Shewanellae strains were identified as S. putrefaciens and S. xiamenensis by 16S rRNA gene sequencing. These isolates recovered from sick eels or freshwater were virulent for European eel by IP challenge (LD 10  CFU g body weight). They also caused 30-38% cumulative mortality, in European eels challenged by a 2-h bath (10  CFU mL ). These results suggest that shewanellosis could be transmitted through water highlighting the fact that hypoxic conditions increase this bacterium levels in water.
[Mh] Termos MeSH primário: Anguilla
Surtos de Doenças
Doenças dos Peixes/epidemiologia
Infecções por Bactérias Gram-Negativas/veterinária
Shewanella putrefaciens/fisiologia
[Mh] Termos MeSH secundário: Anaerobiose
Animais
Doenças dos Peixes/microbiologia
Água Doce
Infecções por Bactérias Gram-Negativas/epidemiologia
Infecções por Bactérias Gram-Negativas/microbiologia
Estações do Ano
Espanha/epidemiologia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1711
[Cu] Atualização por classe:171106
[Lr] Data última revisão:
171106
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161217
[St] Status:MEDLINE
[do] DOI:10.1111/jfd.12574


  8 / 247 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:28032852
[Au] Autor:Guinetti-Ortiz K; Bocanegra-Jesús A; Gómez de la Torre-Del Carpio A
[Ad] Endereço:Escuela de Medicina, Facultad de Ciencias de la Salud, Universidad Peruana de Ciencias Aplicadas, Perú. Address: Avenida Alameda San Marcos, Cuadra 2, Los Cedros de Villa, Chorrillos, Lima, Perú. Email: katia.guinetti@gmail.com.
[Ti] Título:[Osteomyelitis due to Shewanella putrefaciens: case report and literature review].
[Ti] Título:Osteomielitis por Shewanella putrefaciens: reporte de caso y revisión de literatura..
[So] Source:Medwave;16(10):e6642, 2016 Nov 29.
[Is] ISSN:0717-6384
[Cp] País de publicação:Chile
[La] Idioma:spa
[Ab] Resumo:Shewanella putrefaciens is a Gram-negative bacillus and marine pathogen that rarely causes disease in humans. We report a case of osteomyelitis by this organism in a 48-year-old male patient, who presented with pain and erythema of the right foot that was initially diagnosed as cellulitis and did not revert despite treatment. He was transferred to Lima where osteomyelitis was diagnosed and started on empirical treatment with partial regression. A biopsy and culture of the compromised area found S. putrefaciens. The infection was treated according to the antibiotic sensitivity profile of the pathogen. S. putrefaciens infection represents a rare opportunistic infection of devitalized or exposed areas of the body. It is associated with residence in coastal areas and commonly affects the skin and soft tissues. Exceptional cases of osteomyelitis have been reported, but this is the first that involves the metatarsal bones.
[Mh] Termos MeSH primário: Antibacterianos/uso terapêutico
Infecções por Bactérias Gram-Negativas/diagnóstico
Osteomielite/diagnóstico
Shewanella putrefaciens/isolamento & purificação
[Mh] Termos MeSH secundário: Antibacterianos/farmacologia
Biópsia
Infecções por Bactérias Gram-Negativas/tratamento farmacológico
Seres Humanos
Masculino
Testes de Sensibilidade Microbiana
Meia-Idade
Osteomielite/tratamento farmacológico
Osteomielite/microbiologia
Peru
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE; REVIEW
[Nm] Nome de substância:
0 (Anti-Bacterial Agents)
[Em] Mês de entrada:1708
[Cu] Atualização por classe:170807
[Lr] Data última revisão:
170807
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161230
[St] Status:MEDLINE
[do] DOI:10.5867/medwave.2016.10.6642


  9 / 247 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:27866621
[Au] Autor:Huo YC; Li WW; Chen CB; Li CX; Zeng R; Lau TC; Huang TY
[Ad] Endereço:Department of Chemistry, University of Science and Technology of China, Hefei 230026, China; Advanced Laboratory for Environmental Research & Technology (ALERT), USTC-CityU, Suzhou 215123, China; Department of Biology and Chemistry, City University of Hong Kong, Tat Chee Avenue, Kowloon, Hong Ko
[Ti] Título:Biogenic FeS accelerates reductive dechlorination of carbon tetrachloride by Shewanella putrefaciens CN32.
[So] Source:Enzyme Microb Technol;95:236-241, 2016 Dec.
[Is] ISSN:1879-0909
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Dissimilatory metal reducing bacteria (DMRB) widely exist in the subsurface environment and are involved in various contaminant degradation and element geochemical cycling processes. Recent studies suggest that DMRB can biosynthesize metal nanoparticles during metal reduction, but it is unclear yet how such biogenic nanomaterials would affect their decontamination behaviors. In this study, we found that the dechlorination rates of carbon tetrachloride (CT) by Shewanella putrefaciens CN32 was significantly increased by 8 times with the formation of biogenic ferrous sulfide (FeS) nanoparticles. The pasteurized biogenic FeS enabled 5 times faster dechlorination than abiotic FeS that had larger sizes and irregular structure, confirming a significant contribution of the biogenic FeS to CT bioreduction resulting from its good dispersion and relatively high dechlorination activity. This study highlights a potentially important role of biosynthesized nanoparticles in environmental bioremediation.
[Mh] Termos MeSH primário: Tetracloreto de Carbono/metabolismo
Compostos Ferrosos/química
Compostos Ferrosos/metabolismo
Nanopartículas Metálicas/química
Shewanella putrefaciens/metabolismo
[Mh] Termos MeSH secundário: Biodegradação Ambiental
Biotecnologia
Química Verde
Cinética
Nanopartículas Metálicas/ultraestrutura
Nanotecnologia
Oxirredução
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Ferrous Compounds); CL2T97X0V0 (Carbon Tetrachloride); TH5J4TUX6S (ferrous sulfide)
[Em] Mês de entrada:1705
[Cu] Atualização por classe:170515
[Lr] Data última revisão:
170515
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161122
[St] Status:MEDLINE


  10 / 247 MEDLINE  
              first record previous record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:27623340
[Au] Autor:Vidal S; Tapia-Paniagua ST; Moriñigo JM; Lobo C; García de la Banda I; Balebona MDC; Moriñigo MÁ
[Ad] Endereço:Group of Prophylaxis and Biocontrol of Fish Diseases, Departament of Microbiology, Campus de Teatinos s/n, Universidad de Málaga, 29071-Málaga, Spain.
[Ti] Título:Effects on intestinal microbiota and immune genes of Solea senegalensis after suspension of the administration of Shewanella putrefaciens Pdp11.
[So] Source:Fish Shellfish Immunol;58:274-283, 2016 Nov.
[Is] ISSN:1095-9947
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:The interaction host-intestinal microbiota is essential for the immunological homeostasis of the host. Probiotics, prebiotics and synbiotics are promising tools for the manipulation of the intestinal microbiota towards beneficial effects to the host. The objective of this study was to evaluate the modulation effect on the intestinal microbiota and the transcription of genes involved in the immune response in head kidney of Solea senegalensis after administration of diet supplemented with the prebiotic alginate and the probiotic Shewanella putrefaciens Pdp11 CECT 7627 (SpPdp11). The results showed higher adaptability to dietary changes in the intestinal microbiota of fish fed diet with alginate and SpPdp11 together compared to those fish that received an alginate-supplemented diet. The alginate-supplemented diet produced up-regulation of genes encoding proteins involved in immunological responses, such as complement, lysozyme G and transferrin, and oxidative stress, such as NADPH oxidase and glutation peroxidase. On the other hand, the administration of alginate combined with SpPdp11 resulted in a significant increase of the transcription of genes encoding for glutation peroxidase and HSP70, indicating a potential protective effect of SpPdp11 against oxidative stress. In addition, these effects were maintained after the suspension of the probiotic treatment. The relationship between the modulation of the intestinal microbiota and the expression of genes with protective effect against the oxidative stress was demonstrated by the Principal Components Analysis.
[Mh] Termos MeSH primário: Alginatos
Proteínas de Peixes/genética
Linguados
Microbioma Gastrointestinal/efeitos dos fármacos
Prebióticos
Probióticos
Shewanella putrefaciens
[Mh] Termos MeSH secundário: Ração Animal/análise
Animais
Dieta/veterinária
Proteínas de Peixes/metabolismo
Linguados/crescimento & desenvolvimento
Linguados/imunologia
Linguados/microbiologia
Ácido Glucurônico
Ácidos Hexurônicos
Imunidade Inata/efeitos dos fármacos
Estresse Oxidativo/efeitos dos fármacos
Transcrição Genética/efeitos dos fármacos
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Alginates); 0 (Fish Proteins); 0 (Hexuronic Acids); 0 (Prebiotics); 8A5D83Q4RW (Glucuronic Acid); 8C3Z4148WZ (alginic acid)
[Em] Mês de entrada:1703
[Cu] Atualização por classe:170923
[Lr] Data última revisão:
170923
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160914
[St] Status:MEDLINE



página 1 de 25 ir para página                         
   


Refinar a pesquisa
  Base de dados : MEDLINE Formulário avançado   

    Pesquisar no campo  
1  
2
3
 
           



Search engine: iAH v2.6 powered by WWWISIS

BIREME/OPAS/OMS - Centro Latino-Americano e do Caribe de Informação em Ciências da Saúde