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  1 / 31 MEDLINE  
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[PMID]:27037119
[Au] Autor:Lin Z; Torres JP; Tianero MD; Kwan JC; Schmidt EW
[Ad] Endereço:Department of Medicinal Chemistry, University of Utah, Salt Lake City, Utah, USAUniversity of Tennessee and Oak Ridge National Laboratory.
[Ti] Título:Origin of Chemical Diversity in Prochloron-Tunicate Symbiosis.
[So] Source:Appl Environ Microbiol;82(12):3450-60, 2016 Jun 15.
[Is] ISSN:1098-5336
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:UNLABELLED: Diversity-generating metabolism leads to the evolution of many different chemicals in living organisms. Here, by examining a marine symbiosis, we provide a precise evolutionary model of how nature generates a family of novel chemicals, the cyanobactins. We show that tunicates and their symbiotic Prochloron cyanobacteria share congruent phylogenies, indicating that Prochloron phylogeny is related to host phylogeny and not to external habitat or geography. We observe that Prochloron exchanges discrete functional genetic modules for cyanobactin secondary metabolite biosynthesis in an otherwise conserved genetic background. The module exchange leads to gain or loss of discrete chemical functional groups. Because the underlying enzymes exhibit broad substrate tolerance, discrete exchange of substrates and enzymes between Prochloron strains leads to the rapid generation of chemical novelty. These results have implications in choosing biochemical pathways and enzymes for engineered or combinatorial biosynthesis. IMPORTANCE: While most biosynthetic pathways lead to one or a few products, a subset of pathways are diversity generating and are capable of producing thousands to millions of derivatives. This property is highly useful in biotechnology since it enables biochemical or synthetic biological methods to create desired chemicals. A fundamental question has been how nature itself creates this chemical diversity. Here, by examining the symbiosis between coral reef animals and bacteria, we describe the genetic basis of chemical variation with unprecedented precision. New compounds from the cyanobactin family are created by either varying the substrate or importing needed enzymatic functions from other organisms or via both mechanisms. This natural process matches successful laboratory strategies to engineer the biosynthesis of new chemicals and teaches a new strategy to direct biosynthesis.
[Mh] Termos MeSH primário: Produtos Biológicos/metabolismo
Prochloron/fisiologia
Simbiose
Urocordados/microbiologia
[Mh] Termos MeSH secundário: Animais
Redes e Vias Metabólicas
Prochloron/metabolismo
Metabolismo Secundário
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Biological Products)
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170918
[Lr] Data última revisão:
170918
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160403
[St] Status:MEDLINE
[do] DOI:10.1128/AEM.00860-16


  2 / 31 MEDLINE  
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[PMID]:26176189
[Au] Autor:Nielsen DA; Pernice M; Schliep M; Sablok G; Jeffries TC; Kühl M; Wangpraseurt D; Ralph PJ; Larkum AW
[Ad] Endereço:Plant Functional Biology and Climate Change Cluster, University of Technology Sydney, Ultimo, New South Wales, 2007, Australia.
[Ti] Título:Microenvironment and phylogenetic diversity of Prochloron inhabiting the surface of crustose didemnid ascidians.
[So] Source:Environ Microbiol;17(10):4121-32, 2015 Oct.
[Is] ISSN:1462-2920
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:The cyanobacterium Prochloron didemni is primarily found in symbiotic relationships with various marine hosts such as ascidians and sponges. Prochloron remains to be successfully cultivated outside of its host, which reflects a lack of knowledge of its unique ecophysiological requirements. We investigated the microenvironment and diversity of Prochloron inhabiting the upper, exposed surface of didemnid ascidians, providing the first insights into this microhabitat. The pH and O2 concentration in this Prochloron biofilm changes dynamically with irradiance, where photosynthetic activity measurements showed low light adaptation (Ek ∼ 80 ± 7 µmol photons m(-2) s(-1)) but high light tolerance. Surface Prochloron cells exhibited a different fine structure to Prochloron cells from cloacal cavities in other ascidians, the principle difference being a central area of many vacuoles dissected by single thylakoids in the surface Prochloron. Cyanobacterial 16S rDNA pyro-sequencing of the biofilm community on four ascidians resulted in 433 operational taxonomic units (OTUs) where on average -85% (65-99%) of all sequence reads, represented by 136 OTUs, were identified as Prochloron via blast search. All of the major Prochloron-OTUs clustered into independent, highly supported phylotypes separate from sequences reported for internal Prochloron, suggesting a hitherto unexplored genetic variability among Prochloron colonizing the outer surface of didemnids.
[Mh] Termos MeSH primário: Microambiente Celular/fisiologia
Poríferos/microbiologia
Prochloron/classificação
Simbiose/genética
Urocordados/microbiologia
[Mh] Termos MeSH secundário: Animais
Biofilmes
DNA Ribossômico/genética
Variação Genética
Luz
Fotossíntese/genética
Fotossíntese/fisiologia
Filogenia
Prochloron/genética
RNA Ribossômico 16S/genética
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (DNA, Ribosomal); 0 (RNA, Ribosomal, 16S)
[Em] Mês de entrada:1606
[Cu] Atualização por classe:151022
[Lr] Data última revisão:
151022
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:150716
[St] Status:MEDLINE
[do] DOI:10.1111/1462-2920.12983


  3 / 31 MEDLINE  
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[PMID]:23722837
[Au] Autor:Bent AF; Koehnke J; Houssen WE; Smith MC; Jaspars M; Naismith JH
[Ad] Endereço:Biomedical Sciences Research Complex, University of St Andrews, North Haugh, St Andrews, Fife KY16 9ST, Scotland.
[Ti] Título:Structure of PatF from Prochloron didemni.
[So] Source:Acta Crystallogr Sect F Struct Biol Cryst Commun;69(Pt 6):618-23, 2013 Jun.
[Is] ISSN:1744-3091
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Patellamides are macrocyclic peptides with potent biological effects and are a subset of the cyanobactins. Cyanobactins are natural products that are produced by a series of enzymatic transformations and a common modification is the addition of a prenyl group. Puzzlingly, the pathway for patellamides in Prochloron didemni contains a gene, patF, with homology to prenylases, but patellamides are not themselves prenylated. The structure of the protein PatF was cloned, expressed, purified and determined. Prenylase activity could not be demonstrated for the protein, and examination of the structure revealed changes in side-chain identity at the active site. It is suggested that these changes have inactivated the protein. Attempts to mutate these residues led to unfolded protein.
[Mh] Termos MeSH primário: Peptídeos Cíclicos/química
Peptídeos Cíclicos/genética
Prochloron
[Mh] Termos MeSH secundário: Sequência de Aminoácidos
Cristalização
Dados de Sequência Molecular
Peptídeos Cíclicos/isolamento & purificação
Ligação Proteica/fisiologia
Estrutura Secundária de Proteína
Estrutura Terciária de Proteína
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (Peptides, Cyclic); 0 (patellamide F)
[Em] Mês de entrada:1401
[Cu] Atualização por classe:170922
[Lr] Data última revisão:
170922
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:130601
[St] Status:MEDLINE
[do] DOI:10.1107/S1744309113012931


  4 / 31 MEDLINE  
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[PMID]:23185008
[Au] Autor:Kwan JC; Donia MS; Han AW; Hirose E; Haygood MG; Schmidt EW
[Ad] Endereço:Department of Medicinal Chemistry, University of Utah, Salt Lake City, UT 84112, USA.
[Ti] Título:Genome streamlining and chemical defense in a coral reef symbiosis.
[So] Source:Proc Natl Acad Sci U S A;109(50):20655-60, 2012 Dec 11.
[Is] ISSN:1091-6490
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Secondary metabolites are ubiquitous in bacteria, but by definition, they are thought to be nonessential. Highly toxic secondary metabolites such as patellazoles have been isolated from marine tunicates, where their exceptional potency and abundance implies a role in chemical defense, but their biological source is unknown. Here, we describe the association of the tunicate Lissoclinum patella with a symbiotic α-proteobacterium, Candidatus Endolissoclinum faulkneri, and present chemical and biological evidence that the bacterium synthesizes patellazoles. We sequenced and assembled the complete Ca. E. faulkneri genome, directly from metagenomic DNA obtained from the tunicate, where it accounted for 0.6% of sequence data. We show that the large patellazoles biosynthetic pathway is maintained, whereas the remainder of the genome is undergoing extensive streamlining to eliminate unneeded genes. The preservation of this pathway in streamlined bacteria demonstrates that secondary metabolism is an essential component of the symbiotic interaction.
[Mh] Termos MeSH primário: Recifes de Corais
Prochloron/genética
Rhodospirillaceae/genética
Urocordados/microbiologia
[Mh] Termos MeSH secundário: Sequência de Aminoácidos
Animais
Azóis/química
Azóis/metabolismo
Proteínas de Bactérias/genética
Proteínas de Bactérias/metabolismo
Genoma Bacteriano
Metagenoma
Modelos Biológicos
Dados de Sequência Molecular
Filogenia
Policetídeo Sintases/genética
Policetídeo Sintases/metabolismo
Prochloron/fisiologia
RNA Bacteriano/genética
RNA Ribossômico 16S/genética
Rhodospirillaceae/fisiologia
Homologia de Sequência de Aminoácidos
Transdução de Sinais
Simbiose/genética
Simbiose/fisiologia
Urocordados/fisiologia
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, N.I.H., EXTRAMURAL; RESEARCH SUPPORT, U.S. GOV'T, NON-P.H.S.
[Nm] Nome de substância:
0 (Azoles); 0 (Bacterial Proteins); 0 (RNA, Bacterial); 0 (RNA, Ribosomal, 16S); 79956-01-7 (Polyketide Synthases)
[Em] Mês de entrada:1302
[Cu] Atualização por classe:161019
[Lr] Data última revisão:
161019
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:121128
[St] Status:MEDLINE
[do] DOI:10.1073/pnas.1213820109


  5 / 31 MEDLINE  
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[PMID]:22796963
[Au] Autor:Koehnke J; Bent A; Houssen WE; Zollman D; Morawitz F; Shirran S; Vendome J; Nneoyiegbe AF; Trembleau L; Botting CH; Smith MC; Jaspars M; Naismith JH
[Ad] Endereço:Biomedical Sciences Research Complex, University of St Andrews, St Andrews, UK.
[Ti] Título:The mechanism of patellamide macrocyclization revealed by the characterization of the PatG macrocyclase domain.
[So] Source:Nat Struct Mol Biol;19(8):767-72, 2012 Aug.
[Is] ISSN:1545-9985
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Peptide macrocycles are found in many biologically active natural products. Their versatility, resistance to proteolysis and ability to traverse membranes has made them desirable molecules. Although technologies exist to synthesize such compounds, the full extent of diversity found among natural macrocycles has yet to be achieved synthetically. Cyanobactins are ribosomal peptide macrocycles encompassing an extraordinarily diverse range of ring sizes, amino acids and chemical modifications. We report the structure, biochemical characterization and initial engineering of the PatG macrocyclase domain of Prochloron sp. from the patellamide pathway that catalyzes the macrocyclization of linear peptides. The enzyme contains insertions in the subtilisin fold to allow it to recognize a three-residue signature, bind substrate in a preorganized and unusual conformation, shield an acyl-enzyme intermediate from water and catalyze peptide bond formation. The ability to macrocyclize a broad range of nonactivated substrates has wide biotechnology applications.
[Mh] Termos MeSH primário: Proteínas de Bactérias/química
Proteínas de Bactérias/metabolismo
Peptídeos Cíclicos/química
Peptídeos Cíclicos/metabolismo
Prochloron/metabolismo
[Mh] Termos MeSH secundário: Sequência de Aminoácidos
Animais
Proteínas de Bactérias/genética
Modelos Moleculares
Oligopeptídeos/química
Oligopeptídeos/metabolismo
Peptídeos Cíclicos/genética
Prochloron/genética
Conformação Proteica
Estrutura Terciária de Proteína
Proteínas Recombinantes/química
Proteínas Recombinantes/genética
Proteínas Recombinantes/metabolismo
Especificidade por Substrato
Subtilisinas/química
Subtilisinas/genética
Subtilisinas/metabolismo
Simbiose
Urocordados/microbiologia
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (Bacterial Proteins); 0 (Oligopeptides); 0 (Peptides, Cyclic); 0 (Recombinant Proteins); EC 3.4.21.- (Subtilisins)
[Em] Mês de entrada:1210
[Cu] Atualização por classe:170922
[Lr] Data última revisão:
170922
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:120717
[St] Status:MEDLINE
[do] DOI:10.1038/nsmb.2340


  6 / 31 MEDLINE  
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[PMID]:22728755
[Au] Autor:Hamada F; Yokono M; Hirose E; Murakami A; Akimoto S
[Ad] Endereço:Graduate School of Science, Kobe University, Kobe 657-8501, Japan.
[Ti] Título:Excitation energy relaxation in a symbiotic cyanobacterium, Prochloron didemni, occurring in coral-reef ascidians, and in a free-living cyanobacterium, Prochlorothrix hollandica.
[So] Source:Biochim Biophys Acta;1817(11):1992-7, 2012 Nov.
[Is] ISSN:0006-3002
[Cp] País de publicação:Netherlands
[La] Idioma:eng
[Ab] Resumo:The marine cyanobacterium Prochloron is a unique photosynthetic organism that lives in obligate symbiosis with colonial ascidians. We compared Prochloron harbored in four different host species and cultured Prochlorothrix by means of spectroscopic measurements, including time-resolved fluorescence, to investigate host-induced differences in light-harvesting strategies between the cyanobacteria. The light-harvesting efficiency of photosystems including antenna Pcb, PS II-PS I connection, and pigment status, especially that of PS I Red Chls, were different among the four samples. We also discuss relationships between these observed characteristics and the light conditions, to which Prochloron cells are exposed, influenced by distribution pattern in the host colonies, presence or absence of tunic spicules, and microenvironments within the ascidians' habitat.
[Mh] Termos MeSH primário: Prochloron/metabolismo
Prochlorothrix/metabolismo
Simbiose
Urocordados/microbiologia
[Mh] Termos MeSH secundário: Animais
Complexo de Proteína do Fotossistema I/fisiologia
Complexo de Proteína do Fotossistema II/fisiologia
Espectrometria de Fluorescência
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (Photosystem I Protein Complex); 0 (Photosystem II Protein Complex)
[Em] Mês de entrada:1211
[Cu] Atualização por classe:161126
[Lr] Data última revisão:
161126
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:120626
[St] Status:MEDLINE
[do] DOI:10.1016/j.bbabio.2012.06.008


  7 / 31 MEDLINE  
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[PMID]:22134643
[Au] Autor:Behrendt L; Larkum AW; Trampe E; Norman A; Sørensen SJ; Kühl M
[Ad] Endereço:Marine Biological Section, Department of Biology, University of Copenhagen, Helsingør, Denmark. lbehrendt@bio.ku.dk
[Ti] Título:Microbial diversity of biofilm communities in microniches associated with the didemnid ascidian Lissoclinum patella.
[So] Source:ISME J;6(6):1222-37, 2012 Jun.
[Is] ISSN:1751-7370
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:We assessed the microbial diversity and microenvironmental niche characteristics in the didemnid ascidian Lissoclinum patella using 16S rRNA gene sequencing, microsensor and imaging techniques. L. patella harbors three distinct microbial communities spatially separated by few millimeters of tunic tissue: (i) a biofilm on its upper surface exposed to high irradiance and O(2) levels, (ii) a cloacal cavity dominated by the prochlorophyte Prochloron spp. characterized by strong depletion of visible light and a dynamic chemical microenvironment ranging from hyperoxia in light to anoxia in darkness and (iii) a biofilm covering the underside of the animal, where light is depleted of visible wavelengths and enriched in near-infrared radiation (NIR). Variable chlorophyll fluorescence imaging demonstrated photosynthetic activity, and hyperspectral imaging revealed a diversity of photopigments in all microhabitats. Amplicon sequencing revealed the dominance of cyanobacteria in all three layers. Sequences representing the chlorophyll d containing cyanobacterium Acaryochloris marina and anoxygenic phototrophs were abundant on the underside of the ascidian in shallow waters but declined in deeper waters. This depth dependency was supported by a negative correlation between A. marina abundance and collection depth, explained by the increased attenuation of NIR as a function of water depth. The combination of microenvironmental analysis and fine-scale sampling techniques used in this investigation gives valuable first insights into the distribution, abundance and diversity of bacterial communities associated with tropical ascidians. In particular, we show that microenvironments and microbial diversity can vary significantly over scales of a few millimeters in such habitats; which is information easily lost by bulk sampling.
[Mh] Termos MeSH primário: Biofilmes
Cianobactérias/fisiologia
Prochloron/fisiologia
Urocordados/microbiologia
[Mh] Termos MeSH secundário: Animais
Sequência de Bases
Carbono/metabolismo
Clorofila/análise
Análise por Conglomerados
Cianobactérias/genética
Ecossistema
Luz
Imagem Óptica
Oxigênio/metabolismo
Fotossíntese
Análise de Componente Principal
Prochloron/genética
RNA Ribossômico 16S/genética
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (RNA, Ribosomal, 16S); 1406-65-1 (Chlorophyll); 60L1FX1O1U (chlorophyll d); 7440-44-0 (Carbon); S88TT14065 (Oxygen)
[Em] Mês de entrada:1212
[Cu] Atualização por classe:170220
[Lr] Data última revisão:
170220
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:111203
[St] Status:MEDLINE
[do] DOI:10.1038/ismej.2011.181


  8 / 31 MEDLINE  
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[PMID]:22123943
[Au] Autor:Donia MS; Fricke WF; Partensky F; Cox J; Elshahawi SI; White JR; Phillippy AM; Schatz MC; Piel J; Haygood MG; Ravel J; Schmidt EW
[Ad] Endereço:Department of Medicinal Chemistry, University of Utah, Salt Lake City, UT 84112, USA.
[Ti] Título:Complex microbiome underlying secondary and primary metabolism in the tunicate-Prochloron symbiosis.
[So] Source:Proc Natl Acad Sci U S A;108(51):E1423-32, 2011 Dec 20.
[Is] ISSN:1091-6490
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:The relationship between tunicates and the uncultivated cyanobacterium Prochloron didemni has long provided a model symbiosis. P. didemni is required for survival of animals such as Lissoclinum patella and also makes secondary metabolites of pharmaceutical interest. Here, we present the metagenomes, chemistry, and microbiomes of four related L. patella tunicate samples from a wide geographical range of the tropical Pacific. The remarkably similar P. didemni genomes are the most complex so far assembled from uncultivated organisms. Although P. didemni has not been stably cultivated and comprises a single strain in each sample, a complete set of metabolic genes indicates that the bacteria are likely capable of reproducing outside the host. The sequences reveal notable peculiarities of the photosynthetic apparatus and explain the basis of nutrient exchange underlying the symbiosis. P. didemni likely profoundly influences the lipid composition of the animals by synthesizing sterols and an unusual lipid with biofuel potential. In addition, L. patella also harbors a great variety of other bacterial groups that contribute nutritional and secondary metabolic products to the symbiosis. These bacteria possess an enormous genetic potential to synthesize new secondary metabolites. For example, an antitumor candidate molecule, patellazole, is not encoded in the genome of Prochloron and was linked to other bacteria from the microbiome. This study unveils the complex L. patella microbiome and its impact on primary and secondary metabolism, revealing a remarkable versatility in creating and exchanging small molecules.
[Mh] Termos MeSH primário: Metagenoma/fisiologia
Prochloron/metabolismo
[Mh] Termos MeSH secundário: Animais
Genoma
Genômica
Metagenômica
Modelos Biológicos
Modelos Genéticos
Dados de Sequência Molecular
Fotossíntese
Filogenia
RNA Ribossômico 16S/metabolismo
Análise de Sequência de DNA
Simbiose
Urocordados
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, N.I.H., EXTRAMURAL; RESEARCH SUPPORT, NON-U.S. GOV'T; RESEARCH SUPPORT, U.S. GOV'T, NON-P.H.S.
[Nm] Nome de substância:
0 (RNA, Ribosomal, 16S)
[Em] Mês de entrada:1203
[Cu] Atualização por classe:170220
[Lr] Data última revisão:
170220
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:111130
[St] Status:MEDLINE
[do] DOI:10.1073/pnas.1111712108


  9 / 31 MEDLINE  
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[PMID]:20715266
[Au] Autor:Houssen WE; Wright SH; Kalverda AP; Thompson GS; Kelly SM; Jaspars M
[Ad] Endereço:Marine Biodiscovery Centre, Department of Chemistry, University of Aberdeen, Aberdeen AB24 3UE, Scotland, UK.
[Ti] Título:Solution structure of the leader sequence of the patellamide precursor peptide, PatE1-34.
[So] Source:Chembiochem;11(13):1867-73, 2010 Sep 03.
[Is] ISSN:1439-7633
[Cp] País de publicação:Germany
[La] Idioma:eng
[Ab] Resumo:The solution structure of the leader sequence of the patellamide precursor peptide was analysed by using CD and determined with NOE-restrained molecular dynamics calculations. This leader sequence is highly conserved in the precursor peptides of some other cyanobactins harbouring heterocycles, and is assumed to play a role in targeting the precursor peptide to the post-translational machinery. The sequence was observed to form an alpha-helix spanning residues 13-28 with a hydrophobic surface on one side of the helix. This hydrophobic surface is proposed to be the site of the initial binding with modifying enzymes.
[Mh] Termos MeSH primário: Proteínas de Bactérias/química
Precursores de Proteínas/química
[Mh] Termos MeSH secundário: Sequência de Aminoácidos
Dicroísmo Circular
Concentração de Íons de Hidrogênio
Espectroscopia de Ressonância Magnética
Simulação de Dinâmica Molecular
Dados de Sequência Molecular
Peptídeos/química
Prochloron/enzimologia
Sinais Direcionadores de Proteínas
Estrutura Secundária de Proteína
Alinhamento de Sequência
Homologia de Sequência de Aminoácidos
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (Bacterial Proteins); 0 (Peptides); 0 (Protein Precursors); 0 (Protein Sorting Signals)
[Em] Mês de entrada:1101
[Cu] Atualização por classe:170922
[Lr] Data última revisão:
170922
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:100818
[St] Status:MEDLINE
[do] DOI:10.1002/cbic.201000305


  10 / 31 MEDLINE  
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[PMID]:20235396
[Au] Autor:Kojima A; Hirose E
[Ad] Endereço:Faculty of Science, University of the Ryukyus, Senbaru 1, Nishihara, Okinawa 903-0213, Japan.
[Ti] Título:Transfer of prokaryotic algal symbionts from a tropical ascidian (Lissoclinum punctatum) colony to its larvae.
[So] Source:Zoolog Sci;27(2):124-7, 2010 Feb.
[Is] ISSN:0289-0003
[Cp] País de publicação:Japan
[La] Idioma:eng
[Ab] Resumo:Lissoclinum punctatum is a colonial ascidian that harbors the symbiotic prokaryotic alga Prochloron in its tunic and in the peribranchial and common cloacal cavities. Most symbiotic cells in the tunic are intracellular (tunic phycocytes), while those in the cavities are extracellular. We found that neither gametes nor embryos brooded in the tunic were associated with photosymbionts. We determined that algal cells attach to posterior parts of the trunk of hatching larvae swimming in the common cloacal cavity. No symbiont cells were found intracellularly in larval tissues. Thus, extracellular Prochloron cells in the cloacal cavities were transferred to the larvae, but intracellular photosymbionts in the tunic were not. The intracellular symbiosis must be reestablished in each generation after larval settlement.
[Mh] Termos MeSH primário: Prochloron/fisiologia
Simbiose
Urocordados/fisiologia
[Mh] Termos MeSH secundário: Animais
Larva/fisiologia
Larva/ultraestrutura
Urocordados/ultraestrutura
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Em] Mês de entrada:1005
[Cu] Atualização por classe:100317
[Lr] Data última revisão:
100317
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BIREME/OPAS/OMS - Centro Latino-Americano e do Caribe de Informação em Ciências da Saúde