Base de dados : MEDLINE
Pesquisa : B03.510.024.049.525 [Categoria DeCS]
Referências encontradas : 137 [refinar]
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  1 / 137 MEDLINE  
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[PMID]:28854187
[Au] Autor:Malhotra S; Vedithi SC; Blundell TL
[Ad] Endereço:Department of Biochemistry, University of Cambridge, Cambridge, United Kingdom.
[Ti] Título:Decoding the similarities and differences among mycobacterial species.
[So] Source:PLoS Negl Trop Dis;11(8):e0005883, 2017 Aug.
[Is] ISSN:1935-2735
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Mycobacteriaceae comprises pathogenic species such as Mycobacterium tuberculosis, M. leprae and M. abscessus, as well as non-pathogenic species, for example, M. smegmatis and M. thermoresistibile. Genome comparison and annotation studies provide insights into genome evolutionary relatedness, identify unique and pathogenicity-related genes in each species, and explore new targets that could be used for developing new diagnostics and therapeutics. Here, we present a comparative analysis of ten-mycobacterial genomes with the objective of identifying similarities and differences between pathogenic and non-pathogenic species. We identified 1080 core orthologous clusters that were enriched in proteins involved in amino acid and purine/pyrimidine biosynthetic pathways, DNA-related processes (replication, transcription, recombination and repair), RNA-methylation and modification, and cell-wall polysaccharide biosynthetic pathways. For their pathogenicity and survival in the host cell, pathogenic species have gained specific sets of genes involved in repair and protection of their genomic DNA. M. leprae is of special interest owing to its smallest genome (1600 genes and ~1300 psuedogenes), yet poor genome annotation. More than 75% of the pseudogenes were found to have a functional ortholog in the other mycobacterial genomes and belong to protein families such as transferases, oxidoreductases and hydrolases.
[Mh] Termos MeSH primário: Proteínas de Bactérias/genética
Genoma Bacteriano
Mycobacteriaceae/genética
[Mh] Termos MeSH secundário: Mycobacteriaceae/patogenicidade
Fatores de Virulência/genética
[Pt] Tipo de publicação:COMPARATIVE STUDY; JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Bacterial Proteins); 0 (Virulence Factors)
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170917
[Lr] Data última revisão:
170917
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170831
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pntd.0005883


  2 / 137 MEDLINE  
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[PMID]:28569816
[Au] Autor:Russell DG
[Ad] Endereço:Department of Microbiology and Immunology, Cornell University, Ithaca, New York 14853, USA.
[Ti] Título:Microbiology: Diversity breeds tolerance.
[So] Source:Nature;546(7656):44-45, 2017 05 31.
[Is] ISSN:1476-4687
[Cp] País de publicação:England
[La] Idioma:eng
[Mh] Termos MeSH primário: Variação Genética
Mycobacteriaceae/genética
[Mh] Termos MeSH secundário: Repetições de Microssatélites
Fenótipo
Filogenia
[Pt] Tipo de publicação:JOURNAL ARTICLE; COMMENT
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170915
[Lr] Data última revisão:
170915
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170602
[St] Status:MEDLINE
[do] DOI:10.1038/546044a


  3 / 137 MEDLINE  
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[PMID]:27939596
[Au] Autor:Khan M; Hayat M; Khan SA; Iqbal N
[Ad] Endereço:Department of Computer Science, Abdul Wali Khan University Mardan, Pakistan.
[Ti] Título:Unb-DPC: Identify mycobacterial membrane protein types by incorporating un-biased dipeptide composition into Chou's general PseAAC.
[So] Source:J Theor Biol;415:13-19, 2017 Feb 21.
[Is] ISSN:1095-8541
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:This study investigates an efficient and accurate computational method for predicating mycobacterial membrane protein. Mycobacterium is a pathogenic bacterium which is the causative agent of tuberculosis and leprosy. The existing feature encoding algorithms for protein sequence representation such as composition and translation, and split amino acid composition cannot suitably express the mycobacterium membrane protein and their types due to biasness among different types. Therefore, in this study a novel un-biased dipeptide composition (Unb-DPC) method is proposed. The proposed encoding scheme has two advantages, first it avoid the biasness among the different mycobacterium membrane protein and their types. Secondly, the method is fast and preserves protein sequence structure information. The experimental results yield SVM based classification accurately of 97.1% for membrane protein types and 95.0% for discriminating mycobacterium membrane and non-membrane proteins by using jackknife cross validation test. The results exhibit that proposed model achieved significant predictive performance compared to the existing algorithms and will lead to develop a powerful tool for anti-mycobacterium drugs.
[Mh] Termos MeSH primário: Dipeptídeos/química
Proteínas de Membrana/química
Modelos Teóricos
Mycobacteriaceae/química
[Mh] Termos MeSH secundário: Algoritmos
Sequência de Aminoácidos
Viés
Biologia Computacional/métodos
Proteínas de Membrana/classificação
Mycobacteriaceae/ultraestrutura
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Dipeptides); 0 (Membrane Proteins)
[Em] Mês de entrada:1709
[Cu] Atualização por classe:171116
[Lr] Data última revisão:
171116
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161213
[St] Status:MEDLINE


  4 / 137 MEDLINE  
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[PMID]:27887993
[Au] Autor:Hermann M; Bogunovic D
[Ad] Endereço:Department of Microbiology, Icahn School of Medicine at Mount Sinai, NY, NY 10029, USA.
[Ti] Título:ISG15: In Sickness and in Health.
[So] Source:Trends Immunol;38(2):79-93, 2017 Feb.
[Is] ISSN:1471-4981
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:ISG15 is a type I interferon (IFN)-inducible gene encoding a protein with pleiotropic functions, acting both as a soluble molecule and as a protein modifier. Surprisingly, and despite the antiviral functions of ISG15 described in mice, humans born with inactivating mutations of ISG15 do not present with any overt viral phenotype, but are highly susceptible to environmental mycobacteria and have autoinflammatory disease presentations. In vitro, ISG15 deficiency also leads to persistently high levels of type I IFN-stimulated gene expression and to increased resistance to all viruses tested to date. This suggests that ISG15 deficiency increases antiviral responses in humans, in stark contrast to expectations based on mouse experiments. We discuss here the roles of each of the forms of ISG15 in health and disease, as well as the differences between species.
[Mh] Termos MeSH primário: Infecções Bacterianas/imunologia
Citocinas/imunologia
Interferon Tipo I/genética
Mycobacteriaceae/imunologia
Ubiquitinas/imunologia
Viroses/imunologia
[Mh] Termos MeSH secundário: Animais
Autoimunidade/genética
Infecções Bacterianas/genética
Citocinas/genética
Regulação da Expressão Gênica
Seres Humanos
Imunidade
Camundongos
Especificidade da Espécie
Ubiquitinas/genética
Viroses/genética
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Nm] Nome de substância:
0 (Cytokines); 0 (Interferon Type I); 0 (Ubiquitins); 60267-61-0 (ISG15 protein, human)
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170915
[Lr] Data última revisão:
170915
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161127
[St] Status:MEDLINE


  5 / 137 MEDLINE  
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[PMID]:27769030
[Au] Autor:Pitta E; Balabon O; Rogacki MK; Gómez J; Cunningham F; Joosens J; Augustyns K; van der Veken P; Bates R
[Ad] Endereço:Medicinal Chemistry, Department of Pharmaceutical Sciences, University of Antwerp, Universitieitsplein 1, B-2610, Wilrijk, Belgium.
[Ti] Título:Differential characterization using readily accessible NMR experiments of novel N- and O-alkylated quinolin-4-ol, 1,5-naphthyridin-4-ol and quinazolin-4-ol derivatives with antimycobacterial activity.
[So] Source:Eur J Med Chem;125:890-901, 2017 Jan 05.
[Is] ISSN:1768-3254
[Cp] País de publicação:France
[La] Idioma:eng
[Ab] Resumo:During the construction of bioactive molecules, regioselective alkylation of heterocyclic, N/O ambident nucleophiles is a frequently encountered synthetic transformation. In this framework, specific attention is required to unambiguously determine the structures of obtained reaction products. As part of our project on quinoloxyacetamide based antimycobacterial agents, a series of N- or O- alkylated quinolin-4-ol, 1,5-naphthyridin-4-ol and quinazolin-4-ol derivatives were prepared during the course of which we observed unexpected selectivity issues. After finding that no consistent procedure existed in the literature for assigning regioisomers of this type, we applied three readily accessible NMR experiment types ( C NMR, HSQC/HMBC and NOE) to resolve any uncertainties regarding the obtained regioisomeric structures. Furthermore, the antimycobacterial activity of all final compounds was evaluated with the best compound 23 showing potent antitubercular activity (MIC = 1.25 µM) without cytotoxic effects.
[Mh] Termos MeSH primário: Antibacterianos/química
Espectroscopia de Ressonância Magnética/métodos
Mycobacteriaceae/efeitos dos fármacos
Naftiridinas/farmacologia
Quinazolinas/farmacologia
[Mh] Termos MeSH secundário: Alquilação
Antibacterianos/farmacologia
Antituberculosos/química
Sobrevivência Celular/efeitos dos fármacos
Estrutura Molecular
Naftiridinas/química
Quinazolinas/química
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Anti-Bacterial Agents); 0 (Antitubercular Agents); 0 (Naphthyridines); 0 (Quinazolines)
[Em] Mês de entrada:1702
[Cu] Atualização por classe:170221
[Lr] Data última revisão:
170221
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161022
[St] Status:MEDLINE


  6 / 137 MEDLINE  
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[PMID]:27718364
[Au] Autor:Faletrov Y; Brzostek A; Plocinska R; Dziadek J; Rudaya E; Edimecheva I; Shkumatov V
[Ad] Endereço:Research Institute for Physical Chemical Problems, Belarusian State University, Minsk, Belarus; Faculty of Chemistry, Belarusian State University, Minsk, Belarus. Electronic address: yaroslav82@tut.by.
[Ti] Título:Uptake and metabolism of fluorescent steroids by mycobacterial cells.
[So] Source:Steroids;117:29-37, 2017 Jan.
[Is] ISSN:1878-5867
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Fluorescent steroids BODIPY-cholesterol (BPCh) and 7-nitrobenzoxadiazole-4-amino-(NBD)-labeled 22-NBD-chelesterol (22NC) as well as synthesized 20-(NBD)-pregn-5-en-3ß-ol (20NP) were found to undergo bioconversions by Mycobacterium tuberculosis H Rv and M. smegmatis mc 155. The major fluorescent products were determined to be 4-en-3-one derivatives of the compounds. Degradation of NBD fluorophore was also detected in the cases of 22NC and 20NP, but neither NBD degradation nor steroidal part modification were observed for the synthesized 3-(NBD)-cholestane. Mycobacterial 3ß-hydroxysteroid dehydrogenases were concluded to be responsible for the formation of the 4-en-3-one derivatives. All the compounds tested were found to cause staining both membrane lipids and cytosolic lipid droplets when incubated with mycobacteria in different manner, demonstrating ability of the steroids to reside in the compartments. The findings reveal a potential of the compounds for monitoring of steroid interactions with mycobacteria and provide information for design of new probes for this purpose.
[Mh] Termos MeSH primário: Colesterol/metabolismo
Mycobacteriaceae/metabolismo
Esteroides/metabolismo
[Mh] Termos MeSH secundário: Espectroscopia de Ressonância Magnética
Microscopia de Fluorescência
Estrutura Molecular
Mycobacterium tuberculosis/metabolismo
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Steroids); 97C5T2UQ7J (Cholesterol)
[Em] Mês de entrada:1708
[Cu] Atualização por classe:170830
[Lr] Data última revisão:
170830
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161009
[St] Status:MEDLINE


  7 / 137 MEDLINE  
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[PMID]:27515094
[Au] Autor:Li XJ; Liu SW; Jiang ZK; Wu G; Sun CH
[Ad] Endereço:1​Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100050, PR China 2​College of laboratory Medical Science, Hebei North University, Zhangjiakou 075000, PR China.
[Ti] Título:Hoyosella rhizosphaerae sp. nov., a halotolerant actinobacterium isolated from rhizosphere soil of Suaeda salsa, and emended description of the genus Hoyosella.
[So] Source:Int J Syst Evol Microbiol;66(11):4716-4722, 2016 Nov.
[Is] ISSN:1466-5034
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:A halotolerant actinobacterium, designated J12GA03T, was isolated from a rhizosphere soil sample of Suaeda salsa collected from a dried saline lake in Hebei Province, China. Cells were Gram-staining-positive, non-motile and non-spore-forming cocci. Strain J12GA03T grew optimally at 28‒37 °C, 0‒3 % NaCl (w/v) and pH 6.5‒7.5. It contained meso-diaminopimelic acid as the diagnostic diamino acid and arabinose, galactose and ribose as the diagnostic whole-cell sugars. MK-8 and MK-7 were detected as predominant menaquinones. Major fatty acids were C17 : 1ω8c, C16 : 0 and C17 : 0. Polar lipids were phosphatidylethanolamine, diphosphatidylglycerol, phosphatidylinositol, phosphatidylglycerol, phosphoglycolipids, glycolipids, unidentified phospholipids and additional lipids. The muramyl residue was acetyl. Mycolic acids (34-38 carbon atoms) were present. The G+C content of the genomic DNA was 55.8 mol%. It shared the highest 16S rRNA gene sequence similarities with Amycolicicoccus subflavus DQS3-9A1T (98.18 %) and Hoyosella altamirensis OFN S31T (97.75 %). Phylogenetic trees showed that strain J12GA03T firmly formed a distinct monophyletic branch in the clade with A.subflavus DQS3-9A1T and H.altamirensis DSM 45258T. The levels of DNA-DNA relatedness with A.subflavus DSM 45089T and H.altamirensis DSM 45258T were 39.7±3.9 % and 35.7±3.0 %, respectively. Combining the evidence from the polyphasic taxonomic study, strain J12GA03T represents a novel species of the genus Hoyosella, for which the name Hoyosella rhizosphaerae sp. nov. is proposed. The type strain is J12GA03T (=DSM 101985T=CGMCC 1.15478T).
[Mh] Termos MeSH primário: Chenopodiaceae/microbiologia
Mycobacteriaceae/classificação
Filogenia
Rizosfera
Microbiologia do Solo
[Mh] Termos MeSH secundário: Técnicas de Tipagem Bacteriana
Composição de Bases
China
DNA Bacteriano/genética
Ácido Diaminopimélico/química
Ácidos Graxos/química
Glicolipídeos/química
Mycobacteriaceae/genética
Mycobacteriaceae/isolamento & purificação
Fosfolipídeos/química
RNA Ribossômico 16S/genética
Análise de Sequência de DNA
Vitamina K 2/química
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (DNA, Bacterial); 0 (Fatty Acids); 0 (Glycolipids); 0 (Phospholipids); 0 (RNA, Ribosomal, 16S); 11032-49-8 (Vitamin K 2); 583-93-7 (Diaminopimelic Acid)
[Em] Mês de entrada:1708
[Cu] Atualização por classe:170817
[Lr] Data última revisão:
170817
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160813
[St] Status:MEDLINE
[do] DOI:10.1099/ijsem.0.001416


  8 / 137 MEDLINE  
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[PMID]:27514929
[Au] Autor:Hamada M; Shibata C; Sakurai K; Hosoyama A; Oji S; Teramoto K; Tamura T
[Ad] Endereço:1​Biological Resource Center, National Institute of Technology and Evaluation (NBRC), 2-5-8 Kazusakamatari, Kisarazu, Chiba 292-0818, Japan.
[Ti] Título:Reclassification of Amycolicicoccus subflavus as Hoyosella subflava comb. nov. and emended descriptions of the genus Hoyosella and Hoyosella altamirensis.
[So] Source:Int J Syst Evol Microbiol;66(11):4711-4715, 2016 Nov.
[Is] ISSN:1466-5034
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:16S rRNA gene sequences of two type strains belonging to different genera within the suborder Corynebacterineae, namely Hoyosella altamirensis and Amycolicicoccus subflavus, show a similarity of 99.8 %. Therefore, in order to clarify their taxonomic relationship, a polyphasic recharacterization under the same conditions was carried out. The peptidoglycan of H. altamirensis NBRC 109631T and A. subflavus NBRC 109087T was of A1γ type with meso-diaminopimelic acid as their diagnostic diamino acid. Both strains contained MK-8 as the only detected menaquinone, C16 : 0 and C18 : 1ω9c as the major fatty acids, and diphosphatidylglycerol, phosphatidylethanolamine and phosphatidylinositol as the principal polar lipids. The coincidences of these chemotaxonomic features suggested that H. altamirensis and A. subflavus should be assigned to the same genus. Meanwhile, the average nucleotide identity value between both strains and the results of physiological and biochemical tests indicated that H. altamirensis and A. subflavus should be affiliated to different species. Therefore, according to Rules 38 and 41a of the Bacteriological Code, it is proposed that Amycolicicoccus subflavus Wang et al. 2010 be reclassified as Hoyosella subflava comb. nov. (type strain DQS3-9A1T=CGMCC 4.3532T=DSM 45089T=JCM 17490T=NBRC 109087T) and the descriptions of the genus HoyosellaJurado et al. 2009 and Hoyosella altamirensisJurado et al. 2009 are emended accordingly.
[Mh] Termos MeSH primário: Mycobacteriaceae/classificação
Filogenia
Vitamina K 2/análogos & derivados
[Mh] Termos MeSH secundário: Técnicas de Tipagem Bacteriana
Composição de Bases
DNA Bacteriano/genética
Ácidos Graxos/química
Fosfolipídeos/química
RNA Ribossômico 16S/genética
Análise de Sequência de DNA
Vitamina K 2/química
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (DNA, Bacterial); 0 (Fatty Acids); 0 (Phospholipids); 0 (RNA, Ribosomal, 16S); 11032-49-8 (Vitamin K 2); 523-38-6 (vitamin MK 8)
[Em] Mês de entrada:1708
[Cu] Atualização por classe:170817
[Lr] Data última revisão:
170817
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160813
[St] Status:MEDLINE
[do] DOI:10.1099/ijsem.0.001415


  9 / 137 MEDLINE  
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[PMID]:26950194
[Au] Autor:Taramasso L; Tatarelli P; Di Biagio A
[Ad] Endereço:a Infectious Diseases Unit, IRCCS AOU San Martino-IST, University of Genoa , Genoa , Italy.
[Ti] Título:Bloodstream infections in HIV-infected patients.
[So] Source:Virulence;7(3):320-8, 2016 Apr 02.
[Is] ISSN:2150-5608
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:In the combined antiretroviral therapy era, HIV-infected patients remain a vulnerable population for the onset of bloodstream infections (BSI). Worldwide, nontyphoid salmonellae, Streptococcus pneumoniae, Escherichia coli, Staphylococcus aureus and coagulase negative staphylococci are the most important pathogens. Intravenous catheter associated infection, skin-soft tissue infection and endocarditis are associated with Gram-positive bacteremia. Among the Gram-negative, nontyphoidal Salmonella have been previously correlated to sepsis. Other causes of BSI in HIV-infected patients are mycobacteria and fungi. Mycobacteria constitute a major cause of BSI in limited resource countries. Fungal BSI are not frequent and among them Cryptococcus neoformans is the most common life-threatening infection. The degree of immunosuppression remains the key prognostic factor leading to the development of BSI.
[Mh] Termos MeSH primário: Bacteriemia/complicações
Bacteriemia/epidemiologia
Fungemia/complicações
Infecções por HIV/complicações
Infecções por HIV/microbiologia
[Mh] Termos MeSH secundário: Bacteriemia/microbiologia
Cryptococcus neoformans/isolamento & purificação
Endocardite Bacteriana/complicações
Endocardite Bacteriana/epidemiologia
Escherichia coli/isolamento & purificação
Feminino
Fungemia/epidemiologia
Fungemia/microbiologia
Fungos/isolamento & purificação
Infecções por HIV/epidemiologia
Infecções por HIV/virologia
Seres Humanos
Tolerância Imunológica
Masculino
Meia-Idade
Mycobacteriaceae/isolamento & purificação
Salmonella/isolamento & purificação
Staphylococcus aureus/isolamento & purificação
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Em] Mês de entrada:1706
[Cu] Atualização por classe:170607
[Lr] Data última revisão:
170607
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160308
[St] Status:MEDLINE
[do] DOI:10.1080/21505594.2016.1158359


  10 / 137 MEDLINE  
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[PMID]:26939595
[Au] Autor:Patin EC; Willcocks S; Orr S; Ward TH; Lang R; Schaible UE
[Ad] Endereço:Department of Immunology and Infection, Faculty of Infectious and Tropical Disease, London School of Hygiene and Tropical Medicine, London, UK Priority Area Infections, Research Center Borstel, Borstel, Germany Institute of Infection and Immunity, School of Medicine, Cardiff University, Cardiff, UK.
[Ti] Título:Mincle-mediated anti-inflammatory IL-10 response counter-regulates IL-12 in vitro.
[So] Source:Innate Immun;22(3):181-5, 2016 Apr.
[Is] ISSN:1753-4267
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:The role of macrophage-inducible C-type lectin (Mincle) in anti-inflammatory responses has not yet been fully characterized. Herein, we show that engagement of Mincle by trehalose-dimycolate or mycobacteria promotes IL-10 production in macrophages, which causes down-regulation of IL-12p40 secretion. Thus, Mincle mediates both pro- as well as anti-inflammatory responses.
[Mh] Termos MeSH primário: Lectinas Tipo C/metabolismo
Macrófagos/imunologia
Proteínas de Membrana/metabolismo
Mycobacteriaceae/imunologia
Mycobacterium bovis/imunologia
Tuberculose Pulmonar/imunologia
[Mh] Termos MeSH secundário: Animais
Células Cultivadas
Fatores Corda/metabolismo
Regulação da Expressão Gênica
Seres Humanos
Imunidade Inata
Interleucina-10/genética
Interleucina-10/metabolismo
Subunidade p40 da Interleucina-12/genética
Subunidade p40 da Interleucina-12/metabolismo
Lectinas Tipo C/genética
Macrófagos/microbiologia
Proteínas de Membrana/genética
Camundongos
Camundongos Endogâmicos C57BL
Camundongos Knockout
Receptor 2 Toll-Like/genética
Receptor 2 Toll-Like/metabolismo
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (Clecsf8 protein, mouse); 0 (Cord Factors); 0 (Interleukin-12 Subunit p40); 0 (Lectins, C-Type); 0 (Membrane Proteins); 0 (Tlr2 protein, mouse); 0 (Toll-Like Receptor 2); 130068-27-8 (Interleukin-10)
[Em] Mês de entrada:1612
[Cu] Atualização por classe:170922
[Lr] Data última revisão:
170922
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160305
[St] Status:MEDLINE
[do] DOI:10.1177/1753425916636671



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