Base de dados : MEDLINE
Pesquisa : B03.510.024.049.525.500.402 [Categoria DeCS]
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[PMID]:29223275
[Au] Autor:Correa V; Vintch J; Lanks C
[Ad] Endereço:Division of Pulmonary and Critical Care Physiology and Medicine, Harbor-UCLA Medical Center, Torrance, CA.
[Ti] Título:A 26-Year-Old Man From Mexico With Headaches, Dysuria, and a Right Scrotal Mass.
[So] Source:Chest;152(6):e147-e150, 2017 12.
[Is] ISSN:1931-3543
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:CASE PRESENTATION: A 26-year-old man with no medical history was admitted to the hospital for evaluation of his change in mental status. He was noted to be agitated at work and had difficulty walking for 2 days before being brought in to the ED by his family. According to his uncle, the patient had been complaining of a headache and pain with urination for approximately 1 week. He was born in Guerrero, Mexico (a small farm town), and moved to Los Angeles, California, in 2008.
[Mh] Termos MeSH primário: Disuria/etiologia
Cefaleia/etiologia
Hidrocefalia/complicações
Mycobacterium bovis/isolamento & purificação
Escroto/diagnóstico por imagem
Tuberculose dos Genitais Masculinos/diagnóstico
[Mh] Termos MeSH secundário: Adulto
DNA Bacteriano/análise
Diagnóstico Diferencial
Disuria/diagnóstico
Cefaleia/diagnóstico
Seres Humanos
Hidrocefalia/diagnóstico
Imagem por Ressonância Magnética
Masculino
Mycobacterium bovis/genética
Escroto/microbiologia
Tuberculose dos Genitais Masculinos/microbiologia
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Nm] Nome de substância:
0 (DNA, Bacterial)
[Em] Mês de entrada:1712
[Cu] Atualização por classe:180305
[Lr] Data última revisão:
180305
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:171211
[St] Status:MEDLINE


  2 / 8934 MEDLINE  
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Texto completo SciELO Saúde Pública
[PMID]:28453114
[Au] Autor:Leal-Bohórquez AF; Castro-Osorio CM; Wintaco-Martínez LM; Villalobos R; Puerto-Castro GM
[Ad] Endereço:Instituto Nacional de Salud. Bogotá. Colombia. andres_leal@yahoo.com; ccastro@ins.gov.co; mairawm@hotmail.com; gpuerto@ins.gov.co.
[Ti] Título:[Tuberculosis caused by Mycobacterium bovis in workers of bovine tuberculosis sanitation farms in Antioquia, Boyacá and Cundinamarca].
[Ti] Título:Tuberculosis por Mycobacterium bovis en trabajadores de fincas en saneamiento para tuberculosis bovina, de Antioquia, Boyacá y Cundinamarca..
[So] Source:Rev Salud Publica (Bogota);18(5):727-737, 2016 Sep-Oct.
[Is] ISSN:0124-0064
[Cp] País de publicação:Colombia
[La] Idioma:spa
[Ab] Resumo:Objective: To perform classic and molecular epidemiological surveillance of human tuberculosis caused by Mycobacterium bovis in bovine supply chains at farms with PPD positive bovines in the departments of Antioquia, Boyacá and Cundinamarca during a one-year period. Methods: Livestock farms with PPD positive bovines or buffalos were visited in the study departments according to information obtained in the "Programa Nacional de Tuberculosis bovina" (National program on bovine Tuberculosis) released by ICA (Colombian Agriculture and Livestock Institute). Data on socio-demographic information and tuberculosis risk factors associated to the occupation were collected through a survey applied to all workers at the visited farms. Sputum samples were obtained after informed consent. The sputa underwent microbiological and molecular testing to identify members of the M. tuberculosis complex. Results : Thirty-three livestock farms were visited and information of 164 workers from the bovine supply chain was collected. Staying in a PPD positive farm for more than a year, ignorance about the disease and the presence of possible vectors, like dogs and cats, were identified as possible risk factors for developing tuberculosis. No cases of tuberculosis caused by M. bovis or M. tuberculosis in workers of the visited farms were found. Conclusion : No cases of the disease caused by this zoonotic agent were documented in the departments of Antioquia, Boyacá and Cundinamarca.
[Mh] Termos MeSH primário: Doenças dos Trabalhadores Agrícolas/microbiologia
Criação de Animais Domésticos
Fazendas
Mycobacterium bovis
Tuberculose/microbiologia
[Mh] Termos MeSH secundário: Adolescente
Adulto
Idoso
Idoso de 80 Anos ou mais
Doenças dos Trabalhadores Agrícolas/diagnóstico
Animais
Gatos
Bovinos
Colômbia
Vetores de Doenças
Cães
Escolaridade
Seres Humanos
Meia-Idade
Mycobacterium tuberculosis
Saneamento
Escarro/microbiologia
Tuberculose/diagnóstico
Tuberculose Bovina
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180216
[Lr] Data última revisão:
180216
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170429
[St] Status:MEDLINE


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[PMID]:29321154
[Au] Autor:Macleod M
[Ad] Endereço:University of Edinburgh, Edinburgh, UK.
[Ti] Título:Learning lessons from MVA85A, a failed booster vaccine for BCG.
[So] Source:BMJ;360:k66, 2018 01 10.
[Is] ISSN:1756-1833
[Cp] País de publicação:England
[La] Idioma:eng
[Mh] Termos MeSH primário: Mycobacterium bovis/imunologia
Vacinas contra a Tuberculose/imunologia
[Mh] Termos MeSH secundário: Vacina BCG/imunologia
Seres Humanos
Imunização Secundária
Mycobacterium tuberculosis/imunologia
Tuberculose/prevenção & controle
[Pt] Tipo de publicação:EDITORIAL; COMMENT
[Nm] Nome de substância:
0 (BCG Vaccine); 0 (MVA 85A); 0 (Tuberculosis Vaccines)
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180212
[Lr] Data última revisão:
180212
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:180112
[St] Status:MEDLINE
[do] DOI:10.1136/bmj.k66


  4 / 8934 MEDLINE  
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[PMID]:29384896
[Au] Autor:Amanati A; Pouladfar G; Kadivar MR; Sanaei Dashti A; Jafarpour Z; Haghpanah S; Alborzi A
[Ad] Endereço:Alborzi Clinical Microbiology Research Center, Shiraz University of Medical Sciences.
[Ti] Título:A 25-year surveillance of disseminated Bacillus Calmette-Guérin disease treatment in children in Southern Iran.
[So] Source:Medicine (Baltimore);96(52):e9035, 2017 Dec.
[Is] ISSN:1536-5964
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Disseminated Bacillus Calmette-Guérin (BCG) disease is one of the most serious complications of BCG vaccination, mainly among immunocompromised children with high morbidity and mortality.Currently, there is no any consensus with regard to the standard regimen of antituberculosis (anti-TB) agents and duration of treatment in healthy or immunocompromised host in children. The aim of this study is to investigate the effect of various combination treatment strategies for disseminated BCG disease in children.In this cross-sectional study, the outcome of 3 different combination protocols was investigated in 59 patients.All patients were younger than 6 years old. Both possible immunocompetent and proven immunodeficient children were included in a period of 25 years (1991-2014) in a Nemazee referral teaching hospital.The minimum age was 1 month and the maximum was 60 months. The average age of patients was 8 months (8.26 ±â€Š9.73). Out of 59 cases, 32 (54.2%) were female and 27 (45.8%) were male. Based on the primary work up, 52.5% of cases were classified as definite immunodeficient and 47.5% were classified as possible immunocompetent. Overall mortality rate was 50.8%. Mortality rate of disseminated BCG disease in immunocompetent and immunodeficient children was 28.6% and 71%, respectively. The mortality rate was not statistically different between patients treated with different treatment protocols. These results were not affected by immune status and the type of immunodeficiency.More than 2 anti-TB drugs combination will not change outcome of patient with disseminated BCG disease.
[Mh] Termos MeSH primário: Adjuvantes Imunológicos/efeitos adversos
Vacina BCG/efeitos adversos
Mycobacterium bovis/isolamento & purificação
Tuberculose/diagnóstico
Tuberculose/terapia
[Mh] Termos MeSH secundário: Antituberculosos/uso terapêutico
Pré-Escolar
Protocolos Clínicos
Estudos Transversais
Feminino
Seres Humanos
Lactente
Irã (Geográfico)
Masculino
Resultado do Tratamento
Tuberculose/etiologia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Adjuvants, Immunologic); 0 (Antitubercular Agents); 0 (BCG Vaccine)
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180209
[Lr] Data última revisão:
180209
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:180201
[St] Status:MEDLINE
[do] DOI:10.1097/MD.0000000000009035


  5 / 8934 MEDLINE  
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[PMID]:29342164
[Au] Autor:Schoening JM; Corner LAL; Messam LLM; Cassidy JP; Wolfe A
[Ad] Endereço:School of Veterinary Medicine, University College Dublin (UCD), Dublin, Ireland.
[Ti] Título:Environmental dust inhalation in the European badger (Meles meles): Systemic distribution of silica-laden macrophages, pathological changes, and association with Mycobacterium bovis infection status.
[So] Source:PLoS One;13(1):e0190230, 2018.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Chronic inhalation of crystalline silica and silicates may lead to severe lung disease in humans, termed silicosis. The disease is an occupational health concern in miners and related professions worldwide. Silicosis is also a strong risk factor for tuberculosis in humans. Due to its subterranean lifestyle, the European badger (Meles meles) is continuously exposed to environmental dust, while this species is also susceptible to tuberculosis, caused by Mycobacterium bovis. To date, a thorough investigation of mineral dust retention and its possible implication as a risk factor for mycobacterial infection in badgers has not been performed. The aims of this retrospective histological study were (1) to describe the systemic tissue distribution of silica-laden macrophages (SLMs) in badgers; (2) to compare the amount of SLMs in tissues of badgers of differing M. bovis infection status, pulmonary SLM burden and age; and (3) to assess whether inflammation was associated with SLMs. We assessed lung, lymph nodes, liver and spleen of 60 wild-caught badgers of known M. bovis infection status for the presence of SLMs using polarizing light microscopy. SLMs were consistently present within the lungs and were widely distributed throughout the lymphatic system. No inflammatory reaction to SLMs, as occurs in human silicosis, was observed in any tissue. Distribution and amount of SLMs were similar between M. bovis positive and negative badgers, and we were not able to show an association between the amount of SLMs and M. bovis infection status. The amount of SLMs within intra- and extrathoracic lymph nodes was positively associated with the amount of pulmonary SLMs, and with age. This is the first report of substantial and systemic tissue retention of mineral dust particles in a mammalian species lacking associated chronic inflammation (i.e. silicosis). We further highlight different pathogenetic mechanisms underlying silicosis and benign SLM accumulations following siliceous dust inhalation.
[Mh] Termos MeSH primário: Poeira
Macrófagos/microbiologia
Mustelidae/microbiologia
Mycobacterium bovis/isolamento & purificação
[Mh] Termos MeSH secundário: Animais
Dióxido de Silício
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (Dust); 7631-86-9 (Silicon Dioxide)
[Em] Mês de entrada:1801
[Cu] Atualização por classe:180129
[Lr] Data última revisão:
180129
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180118
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0190230


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[PMID]:29235811
[Au] Autor:Siromolot AA; Oliinyk OS; Kolibo DV; Komisarenko SV
[Ti] Título:Mycobacterium tuberculosis antigens MPT63 and MPT83 increase phagocytic activity of murine peritoneal macrophages.
[So] Source:Ukr Biochem J;88(5):62-70, 2016 Sep-Oct.
[Is] ISSN:2409-4943
[Cp] País de publicação:Ukraine
[La] Idioma:eng
[Ab] Resumo:Macrophages (MΦ) are the most described and characterized target and host of mycobacteria. Like other cells of innate immunity MΦ have a wide range of receptor molecules which interact with different pathogen associated molecular patterns (PAMPs). Immunodominant proteins MPT63 and MPT83 that are synthesized in abundance by Mycobacterium bovis or Mycobacterium tuberculosis strains could be involved in development of tuberculosis infection. The aim of this study was to search for effects of these mycobacterial antigens on target cells. For this aim full-sized sequences of MPT83 (rMPT83full) and MPT63 antigens were cloned into plasmid pET24a(+). The increase of phagocytic activity of murine peritoneal macrophages was demonstrated, but not of macrophage-like cells from J774 cell line, which were treated by rMPT63 and rMPT83full proteins for 24 h. This effect of such antigens can be considered as a way to facilitate the consumption of mycobacterial cells by macrophages to avoid other effector mechanisms of innate and adaptive immunity.
[Mh] Termos MeSH primário: Antígenos de Bactérias/imunologia
Proteínas de Bactérias/imunologia
Macrófagos Peritoneais/imunologia
Proteínas de Membrana/imunologia
Mycobacterium tuberculosis/imunologia
Fagocitose/efeitos dos fármacos
[Mh] Termos MeSH secundário: Animais
Antígenos de Bactérias/genética
Antígenos de Bactérias/farmacologia
Proteínas de Bactérias/genética
Proteínas de Bactérias/farmacologia
Clonagem Molecular
Escherichia coli/genética
Escherichia coli/metabolismo
Expressão Gênica
Genes Reporter
Vetores Genéticos/química
Vetores Genéticos/metabolismo
Proteínas de Fluorescência Verde/genética
Proteínas de Fluorescência Verde/metabolismo
Proteínas Luminescentes/genética
Proteínas Luminescentes/metabolismo
Macrófagos Peritoneais/microbiologia
Proteínas de Membrana/genética
Proteínas de Membrana/farmacologia
Camundongos
Mycobacterium bovis/química
Mycobacterium bovis/imunologia
Mycobacterium tuberculosis/química
Especificidade de Órgãos
Proteínas Recombinantes/genética
Proteínas Recombinantes/imunologia
Proteínas Recombinantes/farmacologia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Antigens, Bacterial); 0 (Bacterial Proteins); 0 (Luminescent Proteins); 0 (MPB83 protein, Mycobacterium); 0 (MPT63 antigen, Mycobacterium tuberculosis); 0 (Membrane Proteins); 0 (Recombinant Proteins); 0 (enhanced green fluorescent protein); 0 (red fluorescent protein); 147336-22-9 (Green Fluorescent Proteins)
[Em] Mês de entrada:1801
[Cu] Atualização por classe:180116
[Lr] Data última revisão:
180116
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171214
[St] Status:MEDLINE
[do] DOI:10.15407/ubj88.05.062


  7 / 8934 MEDLINE  
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[PMID]:27778282
[Au] Autor:Ravindran MS; Wenk MR
[Ad] Endereço:NUS Graduate School for Integrative Sciences and Engineering, National University of Singapore (NUS), Singapore, 117456, Singapore.
[Ti] Título:Activity-Based Lipid Esterase Profiling of M. bovis BCG at Different Metabolic States Using Tetrahydrolipstatin (THL) as Bait.
[So] Source:Methods Mol Biol;1491:75-85, 2017.
[Is] ISSN:1940-6029
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:This chapter provides a step-by-step protocol using activity-based protein profiling (ABPP) as a chemical-proteomic tool to survey the antibiotic properties of a small molecule. Here, we investigate the molecular mechanism behind the bactericidal activity of tetrahydrolipstatin (THL). ABPP relies on small molecule probes that target the active site of specific enzymes in complex proteomes. These probes in turn are equipped with a reporter tag that allows capturing, visualization, enrichment, identification, and quantification of its targets either in vitro or in situ. THL possesses bactericidal activities, but its precise spectrum of molecular targets is poorly characterized. Here, we used THL analogs functionalized to enable Huisgen-base cycloaddition, commonly known as "click chemistry," to identify target proteins after enrichment from mycobacterial cell lysates obtained from different physiological conditions.
[Mh] Termos MeSH primário: Esterases/metabolismo
Lactonas/farmacologia
Metabolismo dos Lipídeos
Mycobacterium bovis/enzimologia
Proteômica
[Mh] Termos MeSH secundário: Antibacterianos/farmacologia
Química Click
Reação de Cicloadição
Inibidores Enzimáticos/farmacologia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Anti-Bacterial Agents); 0 (Enzyme Inhibitors); 0 (Lactones); 95M8R751W8 (orlistat); EC 3.1.- (Esterases)
[Em] Mês de entrada:1801
[Cu] Atualização por classe:180116
[Lr] Data última revisão:
180116
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161026
[St] Status:MEDLINE


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[PMID]:28460600
[Au] Autor:Yates GF; Price-Carter M; Bland K; Joyce MA; Khan F; Surrey M; de Lisle GW
[Ad] Endereço:AgResearch Limited, Hopkirk Research Institute, Grasslands Research Centre, Palmerston North, New Zealand.
[Ti] Título:Comparison of the BBL mycobacteria growth indicator tube, the BACTEC 12B, and solid media for the isolation of Mycobacterium bovis.
[So] Source:J Vet Diagn Invest;29(4):508-512, 2017 Jul.
[Is] ISSN:1943-4936
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:We compared different methods for their ability to isolate Mycobacterium bovis from tissue samples from animals with lesions resembling bovine tuberculosis. In the first trial, M. bovis was isolated from 86 of 200 tissue samples that were cultured using 2 liquid media, BACTEC 12B and BBL mycobacteria growth indicator tube (MGIT), and a solid medium, Middlebrook 7H11 supplemented with pyruvate (7H11P). M. bovis was isolated from 2 samples with MGIT but not BACTEC 12B. M. bovis was isolated from 9 samples with BACTEC but not MGIT; these 9 samples came from the North Canterbury/Marlborough region of New Zealand. The proportion of tissues from which M. bovis was isolated with BACTEC 12B or MGIT and the mean time for isolation was different for samples from the North Canterbury/Marlborough region but not the rest of New Zealand. In the second trial, M. bovis was isolated from 401 of 1,033 tissues that were cultured using MGIT, Middlebrook 7H9 broth, or solid 7H11P. The proportion of isolates of M. bovis and the mean time for their isolation with MGIT was different for the North Canterbury/Marlborough and the rest of New Zealand. The reason for this difference was not determined but may be related to the genotypes present in this region. Genotyping using variable number tandem repeats (VNTRs) of 197 isolates of M. bovis revealed that the 44 isolates from North Canterbury/Marlborough were represented by 2 closely related VNTR types that were not found in 153 isolates from the remainder of New Zealand.
[Mh] Termos MeSH primário: Técnicas Bacteriológicas/veterinária
Cervos
Mycobacterium bovis/isolamento & purificação
Tuberculose Bovina/diagnóstico
Tuberculose/veterinária
[Mh] Termos MeSH secundário: Animais
Técnicas Bacteriológicas/instrumentação
Técnicas Bacteriológicas/métodos
Bovinos
Meios de Cultura/análise
Nova Zelândia
Tuberculose/diagnóstico
Tuberculose/microbiologia
Tuberculose Bovina/microbiologia
[Pt] Tipo de publicação:COMPARATIVE STUDY; JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Culture Media)
[Em] Mês de entrada:1712
[Cu] Atualização por classe:171212
[Lr] Data última revisão:
171212
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170503
[St] Status:MEDLINE
[do] DOI:10.1177/1040638717697763


  9 / 8934 MEDLINE  
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[PMID]:28902383
[Au] Autor:Geerdes-Fenge HF; Stubbe F; Löbermann M; Warnke P; Erbersdobler A; Reisinger EC
[Ad] Endereço:Abteilung für Tropenmedizin und Infektionskrankheiten und Sektion Nephrologie, Universitätsmedizin Rostock.
[Ti] Título:[BCGitis with Involvement of Lung, Liver and Bone Marrow after Immunotherapy of Urothelial Cancer].
[Ti] Título:BCGitis mit Lungen-, Leber- und Knochenmarksbeteiligung nach Immuntherapie eines Urothelkarzinoms..
[So] Source:Dtsch Med Wochenschr;142(18):1375-1378, 2017 Sep.
[Is] ISSN:1439-4413
[Cp] País de publicação:Germany
[La] Idioma:ger
[Ab] Resumo:A 77-year-old patient with transurethral resection of a bladder tumor was transferred due to persistent fever and progressive dyspnea despite antibiotic therapy for suspected urinary tract infection. Repeating the medical history revealed that a BCG immunotherapy of his non-muscle-invasive bladder carcinoma was performed the day before fever developed. Therefore, BCGitis was suspected. Laboratory parameters showed pancytopenia, elevated liver enzymes, eleveated C-reactive protein and hypoxemia. The CT scan showed multiple miliary lesions of the lung, the bone marrow biopsy revealed granuloma. M. bovis BCG was cultured from urine and bronchoalveolar lavage fluid. Therapy with isoniazide, rifampine, ethambutol and initially prednisolone caused rapid improvement. BCGitis is a rare complication of BCG immunotherapy of non-muscle-invasive bladder carcinoma.
[Mh] Termos MeSH primário: Imunoterapia/efeitos adversos
Mycobacterium bovis/imunologia
Neoplasias da Bexiga Urinária/terapia
[Mh] Termos MeSH secundário: Idoso
Dispneia/etiologia
Febre/etiologia
Seres Humanos
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170927
[Lr] Data última revisão:
170927
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170914
[St] Status:MEDLINE
[do] DOI:10.1055/s-0043-115775


  10 / 8934 MEDLINE  
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[PMID]:28879829
[Au] Autor:Lombardi G; Botti I; Pacciarini ML; Boniotti MB; Roncarati G; Dal Monte P
[Ad] Endereço:Department of Experimental, Diagnostic and Specialty Medicine - Microbiology Unit,Alma Mater Studiorum University of Bologna - St. Orsola-Malpighi University Hospital,Bologna,Italy.
[Ti] Título:Five-year surveillance of human tuberculosis caused by Mycobacterium bovis in Bologna, Italy: an underestimated problem.
[So] Source:Epidemiol Infect;145(14):3035-3039, 2017 10.
[Is] ISSN:1469-4409
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Human tuberculosis (TB) caused by Mycobacterium bovis surveillance is affected by a lack of data. The aims of the present study were: (i) to estimate the proportion of human TB caused by M. bovis over a period of 5 years in Bologna, Northern Italy, which, like most Western European countries, has been declared bovine TB-free; (ii) to compare the genetic profiles of M. bovis strains identified in humans with those circulating in cattle in the last 15 years in Italy. Among 511 TB patients, the proportion of human TB caused by M. bovis was 1·76%, significantly associated to extra-pulmonary localization (P = 0·004) and to being elderly (P < 0·001) and Italy-born (P = 0·036). The molecular epidemiology analysis by spoligotyping and Multilocus Variable Tandem Repeat Analysis confirmed that most M. bovis strains from Italy-born patients matched those circulating in cattle herds in Italy between 2001 and 2016. Two cases of Mycobacterium bovis BCG infection were also characterized. In conclusion, the rate of human TB caused by M. bovis was not negligible, highlighting the relevance of molecular typing in evaluating the effectiveness of programmes designed to eradicate TB in cattle in Italy.
[Mh] Termos MeSH primário: Genótipo
Mycobacterium bovis/fisiologia
Tuberculose/epidemiologia
[Mh] Termos MeSH secundário: Adolescente
Adulto
Idoso
Idoso de 80 Anos ou mais
Feminino
Seres Humanos
Lactente
Itália/epidemiologia
Masculino
Meia-Idade
Repetições Minissatélites
Tipagem de Sequências Multilocus
Mycobacterium bovis/genética
Tuberculose/microbiologia
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171125
[Lr] Data última revisão:
171125
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170908
[St] Status:MEDLINE
[do] DOI:10.1017/S0950268817001996



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