Base de dados : MEDLINE
Pesquisa : B04.123.150 [Categoria DeCS]
Referências encontradas : 53 [refinar]
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[PMID]:27623402
[Au] Autor:Cruz-Flores R; Cáceres-Martínez J; Muñoz-Flores M; Vásquez-Yeomans R; Hernández Rodriguez M; Ángel Del Río-Portilla M; Rocha-Olivares A; Castro-Longoria E
[Ad] Endereço:Centro de Investigación Científica y de Educación Superior de Ensenada (CICESE), Carretera Ensenada-Tijuana No. 3918, Zona Playitas, 22860, Ensenada, Baja California, Mexico.
[Ti] Título:Hyperparasitism by the bacteriophage (Caudovirales) infecting Candidatus Xenohaliotis californiensis (Rickettsiales-like prokaryote) parasite of wild abalone Haliotis fulgens and Haliotis corrugata from the Peninsula of Baja California, Mexico.
[So] Source:J Invertebr Pathol;140:58-67, 2016 Oct.
[Is] ISSN:1096-0805
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Candidatus Xenohaliotis californiensis (CXc) is a Rickettsiales-like prokaryote that is considered the causal agent of Withering Syndrome (WS), a chronic disease of abalone, from the west coast of North America and it is listed by the International Organization for Animal Health (OIE) as a reportable agent due to its pathogenicity. This bacterium in red abalone Haliotis rufescens, black abalone Haliotis cracherodii, and yellow abalone Haliotis corrugata from California, US and Baja California, Mexico has been found to be infected by a bacteriophage. To date, there is no information on the epizootiology of CXc and its bacteriophage in natural populations of abalone; furthermore, it is unknown if the bacteriophage was also present in CXc infecting blue abalone Haliotis fulgens. The objective of this study was to determine the distribution, prevalence and intensity of CXc, as well as to determine the distribution and prevalence of the bacteriophage and to study interactions between host sex and hyperparasitism in blue abalone and yellow abalone. Tissue samples were obtained from seven localities where the commercial capture of wild abalone is carried out. Samplings were conducted throughout the 2012-2013 capture seasons and a total of 182 blue abalone and 170 yellow abalone were obtained. The prevalence and intensity of CXc and the prevalence of the bacteriophage were determined by histology. The identity of CXc was confirmed by PCR, product sequence analysis and in situ hybridization while the identity of the bacteriophage was corroborated by TEM. The prevalence of CXc infected and uninfected by the bacteriophage was 80% in blue abalone and 62% in yellow abalone. Low infection intensities were found in 86% of blue abalone and 82% of yellow abalone. Infection intensity was significantly higher in undifferentiated yellow abalone. The bacteriophage in CXc showed a prevalence of 22% and 31% in blue abalone and yellow abalone respectively. These results show that CXc and its bacteriophage are widely distributed in the peninsula of Baja California and that they are well established in natural populations of blue abalone and yellow abalone. Additionally, this data constitutes the first record of a bacteriophage in blue abalone.
[Mh] Termos MeSH primário: Caudovirales
Gastrópodes/parasitologia
Rickettsieae/virologia
Viroses/veterinária
[Mh] Termos MeSH secundário: Animais
Hibridização In Situ
México
Reação em Cadeia da Polimerase
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170926
[Lr] Data última revisão:
170926
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160914
[St] Status:MEDLINE


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[PMID]:27312355
[Au] Autor:Subirats J; Sànchez-Melsió A; Borrego CM; Balcázar JL; Simonet P
[Ad] Endereço:Catalan Institute for Water Research (ICRA), Scientific and Technological Park of the University of Girona, Girona, Spain.
[Ti] Título:Metagenomic analysis reveals that bacteriophages are reservoirs of antibiotic resistance genes.
[So] Source:Int J Antimicrob Agents;48(2):163-7, 2016 Aug.
[Is] ISSN:1872-7913
[Cp] País de publicação:Netherlands
[La] Idioma:eng
[Ab] Resumo:A metagenomics approach was applied to explore the presence of antibiotic resistance genes (ARGs) in bacteriophages from hospital wastewater. Metagenomic analysis showed that most phage sequences affiliated to the order Caudovirales, comprising the tailed phage families Podoviridae, Siphoviridae and Myoviridae. Moreover, the relative abundance of ARGs in the phage DNA fraction (0.26%) was higher than in the bacterial DNA fraction (0.18%). These differences were particularly evident for genes encoding ATP-binding cassette (ABC) and resistance-nodulation-cell division (RND) proteins, phosphotransferases, ß-lactamases and plasmid-mediated quinolone resistance. Analysis of assembled contigs also revealed that blaOXA-10, blaOXA-58 and blaOXA-24 genes belonging to class D ß-lactamases as well as a novel blaTEM (98.9% sequence similarity to the blaTEM-1 gene) belonging to class A ß-lactamases were detected in a higher proportion in phage DNA. Although preliminary, these findings corroborate the role of bacteriophages as reservoirs of resistance genes and thus highlight the necessity to include them in future studies on the emergence and spread of antibiotic resistance in the environment.
[Mh] Termos MeSH primário: Bactérias/virologia
Bacteriófagos/genética
Farmacorresistência Bacteriana
Transferência Genética Horizontal
Genes Bacterianos
Genes Virais
Águas Residuais/virologia
[Mh] Termos MeSH secundário: Bactérias/efeitos dos fármacos
Bacteriófagos/classificação
Bacteriófagos/isolamento & purificação
Caudovirales/classificação
Caudovirales/genética
Caudovirales/isolamento & purificação
Hospitais
Metagenômica
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Waste Water)
[Em] Mês de entrada:1702
[Cu] Atualização por classe:170215
[Lr] Data última revisão:
170215
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160618
[St] Status:MEDLINE


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[PMID]:26472517
[Au] Autor:Roux S; Enault F; Ravet V; Colombet J; Bettarel Y; Auguet JC; Bouvier T; Lucas-Staat S; Vellet A; Prangishvili D; Forterre P; Debroas D; Sime-Ngando T
[Ad] Endereço:Université Blaise Pascal, Laboratoire 'Microorganismes: Génome et Environnement', Clermont Université, Clermont-Ferrand, France.
[Ti] Título:Analysis of metagenomic data reveals common features of halophilic viral communities across continents.
[So] Source:Environ Microbiol;18(3):889-903, 2016 Mar.
[Is] ISSN:1462-2920
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Microbial communities from hypersaline ponds, dominated by halophilic archaea, are considered specific of such extreme conditions. The associated viral communities have accordingly been shown to display specific features, such as similar morphologies among different sites. However, little is known about the genetic diversity of these halophilic viral communities across the Earth. Here, we studied viral communities in hypersaline ponds sampled on the coast of Senegal (8-36% of salinity) using metagenomics approach, and compared them with hypersaline viromes from Australia and Spain. The specificity of hyperhalophilic viruses could first be demonstrated at a community scale, salinity being a strong discriminating factor between communities. For the major viral group detected in all samples (Caudovirales), only a limited number of halophilic Caudovirales clades were highlighted. These clades gather viruses from different continents and display consistent genetic composition, indicating that they represent related lineages with a worldwide distribution. Non-tailed hyperhalophilic viruses display a greater rate of gene transfer and recombination, with uncharacterized genes conserved across different kind of viruses and plasmids. Thus, hypersaline viral communities around the world appear to form a genetically consistent community that are likely to harbour new genes coding for enzymes specifically adapted to these environments.
[Mh] Termos MeSH primário: Caudovirales/genética
Genoma Viral/genética
Tanques/virologia
Salinidade
[Mh] Termos MeSH secundário: Austrália
Caudovirales/isolamento & purificação
Mapeamento Cromossômico
Variação Genética
Metagenômica
Senegal
Espanha
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Em] Mês de entrada:1611
[Cu] Atualização por classe:161230
[Lr] Data última revisão:
161230
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:151017
[St] Status:MEDLINE
[do] DOI:10.1111/1462-2920.13084


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[PMID]:26785457
[Au] Autor:Young R; Gill JJ
[Ad] Endereço:Center for Phage Technology, Texas A&M University, College Station, TX 77843, USA. Department of Biochemistry and Biophysics, Texas A&M University, College Station, TX 77843, USA. ryland@tamu.edu jason.gill@tamu.edu.
[Ti] Título:MICROBIOLOGY. Phage therapy redux--What is to be done?
[So] Source:Science;350(6265):1163-4, 2015 Dec 04.
[Is] ISSN:1095-9203
[Cp] País de publicação:United States
[La] Idioma:eng
[Mh] Termos MeSH primário: Bacteriocinas
Terapia Biológica/métodos
Caudovirales
Infecções por Bactérias Gram-Positivas/terapia
[Mh] Termos MeSH secundário: Queimaduras/microbiologia
Queimaduras/terapia
Farmacorresistência Bacteriana
Seres Humanos
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Bacteriocins)
[Em] Mês de entrada:1602
[Cu] Atualização por classe:160120
[Lr] Data última revisão:
160120
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160120
[St] Status:MEDLINE
[do] DOI:10.1126/science.aad6791


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[PMID]:26670244
[Au] Autor:Garcia-Doval C; Castón JR; Luque D; Granell M; Otero JM; Llamas-Saiz AL; Renouard M; Boulanger P; van Raaij MJ
[Ad] Endereço:Departamento de Estructura de Macromoléculas, Centro Nacional de Biotecnología, Consejo Superior de Investigaciones Científicas (CNB-CSIC), calle Darwin 3, E-28049 Madrid, Spain. c.garcia@bioc.uzh.ch.
[Ti] Título:Structure of the Receptor-Binding Carboxy-Terminal Domain of the Bacteriophage T5 L-Shaped Tail Fibre with and without Its Intra-Molecular Chaperone.
[So] Source:Viruses;7(12):6424-40, 2015 Dec 08.
[Is] ISSN:1999-4915
[Cp] País de publicação:Switzerland
[La] Idioma:eng
[Ab] Resumo:Bacteriophage T5, a Siphovirus belonging to the order Caudovirales, has a flexible, three-fold symmetric tail, to which three L-shaped fibres are attached. These fibres recognize oligo-mannose units on the bacterial cell surface prior to infection and are composed of homotrimers of the pb1 protein. Pb1 has 1396 amino acids, of which the carboxy-terminal 133 residues form a trimeric intra-molecular chaperone that is auto-proteolyzed after correct folding. The structure of a trimer of residues 970-1263 was determined by single anomalous dispersion phasing using incorporated selenomethionine residues and refined at 2.3 Å resolution using crystals grown from native, methionine-containing, protein. The protein inhibits phage infection by competition. The phage-distal receptor-binding domain resembles a bullet, with the walls formed by partially intertwined beta-sheets, conferring stability to the structure. The fold of the domain is novel and the topology unique to the pb1 structure. A site-directed mutant (Ser1264 to Ala), in which auto-proteolysis is impeded, was also produced, crystallized and its 2.5 Å structure solved by molecular replacement. The additional chaperone domain (residues 1263-1396) consists of a central trimeric alpha-helical coiled-coil flanked by a mixed alpha-beta domain. Three long beta-hairpin tentacles, one from each chaperone monomer, extend into long curved grooves of the bullet-shaped domain. The chaperone-containing mutant did not inhibit infection by competition.
[Mh] Termos MeSH primário: Chaperonas Moleculares/química
Siphoviridae/química
Proteínas da Cauda Viral/química
[Mh] Termos MeSH secundário: Caudovirales/química
Caudovirales/fisiologia
Cristalografia por Raios X
Modelos Moleculares
Chaperonas Moleculares/genética
Proteínas Mutantes/química
Proteínas Mutantes/genética
Conformação Proteica
Siphoviridae/fisiologia
Proteínas da Cauda Viral/genética
Ligação Viral
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (Molecular Chaperones); 0 (Mutant Proteins); 0 (Viral Tail Proteins)
[Em] Mês de entrada:1609
[Cu] Atualização por classe:170220
[Lr] Data última revisão:
170220
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:151217
[St] Status:MEDLINE
[do] DOI:10.3390/v7122946


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[PMID]:26529193
[Au] Autor:Antunes A; Alam I; Simões MF; Daniels C; Ferreira AJ; Siam R; El-Dorry H; Bajic VB
[Ad] Endereço:Computational Bioscience Research Center (CBRC), Computer, Electrical and Mathematical Sciences and Engineering Division (CEMSE), King Abdullah University of Science and Technology (KAUST), Thuwal 23955-6900, Saudi Arabia. Electronic address: andre.antunes@kaust.edu.sa.
[Ti] Título:First Insights into the Viral Communities of the Deep-sea Anoxic Brines of the Red Sea.
[So] Source:Genomics Proteomics Bioinformatics;13(5):304-9, 2015 Oct.
[Is] ISSN:2210-3244
[Cp] País de publicação:China
[La] Idioma:eng
[Ab] Resumo:The deep-sea brines of the Red Sea include some of the most extreme and unique environments on Earth. They combine high salinities with increases in temperature, heavy metals, hydrostatic pressure, and anoxic conditions, creating unique settings for thriving populations of novel extremophiles. Despite a recent increase of studies focusing on these unusual biotopes, their viral communities remain unexplored. The current survey explores four metagenomic datasets obtained from different brine-seawater interface samples, focusing specifically on the diversity of their viral communities. Data analysis confirmed that the particle-attached viral communities present in the brine-seawater interfaces were diverse and generally dominated by Caudovirales, yet appearing distinct from sample to sample. With a level of caution, we report the unexpected finding of Phycodnaviridae, which infects algae and plants, and trace amounts of insect-infecting Iridoviridae. Results from Kebrit Deep revealed stratification in the viral communities present in the interface: the upper-interface was enriched with viruses associated with typical marine bacteria, while the lower-interface was enriched with haloviruses and halophages. These results provide first insights into the unexplored viral communities present in deep-sea brines of the Red Sea, representing one of the first steps for ongoing and future sampling efforts and studies.
[Mh] Termos MeSH primário: Caudovirales/isolamento & purificação
Phycodnaviridae/isolamento & purificação
Vírus de Plantas/isolamento & purificação
Água do Mar/virologia
[Mh] Termos MeSH secundário: Archaea/genética
Archaea/virologia
Bactérias/genética
Bactérias/virologia
Caudovirales/genética
Oceano Índico
Metagenômica/métodos
Phycodnaviridae/genética
Vírus de Plantas/genética
Sais
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (Salts); 0 (brine)
[Em] Mês de entrada:1608
[Cu] Atualização por classe:170220
[Lr] Data última revisão:
170220
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:151104
[St] Status:MEDLINE


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[PMID]:26319032
[Au] Autor:Brooks J; Watson AJ
[Ad] Endereço:Institute of Food Research and Norwich Medical School, University of East Anglia, Norwich, United Kingdom.
[Ti] Título:The Enteric Virome in Inflammatory Bowel Disease.
[So] Source:Gastroenterology;149(4):1120-1, 2015 Oct.
[Is] ISSN:1528-0012
[Cp] País de publicação:United States
[La] Idioma:eng
[Mh] Termos MeSH primário: Caudovirales/isolamento & purificação
Colite Ulcerativa/virologia
Doença de Crohn/virologia
Disbiose/virologia
Microviridae/isolamento & purificação
[Mh] Termos MeSH secundário: Seres Humanos
[Pt] Tipo de publicação:COMMENT; JOURNAL ARTICLE
[Em] Mês de entrada:1512
[Cu] Atualização por classe:150926
[Lr] Data última revisão:
150926
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:150831
[St] Status:MEDLINE


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[PMID]:25666643
[Au] Autor:Ray K
[Ti] Título:IBD. Gut microbiota in IBD goes viral.
[So] Source:Nat Rev Gastroenterol Hepatol;12(3):122, 2015 Mar.
[Is] ISSN:1759-5053
[Cp] País de publicação:England
[La] Idioma:eng
[Mh] Termos MeSH primário: Caudovirales/isolamento & purificação
Colite Ulcerativa/virologia
Doença de Crohn/virologia
Disbiose/virologia
Microviridae/isolamento & purificação
[Mh] Termos MeSH secundário: Seres Humanos
[Pt] Tipo de publicação:COMMENT; JOURNAL ARTICLE
[Em] Mês de entrada:1505
[Cu] Atualização por classe:170606
[Lr] Data última revisão:
170606
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:150211
[St] Status:MEDLINE
[do] DOI:10.1038/nrgastro.2015.26


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[PMID]:25619688
[Au] Autor:Norman JM; Handley SA; Baldridge MT; Droit L; Liu CY; Keller BC; Kambal A; Monaco CL; Zhao G; Fleshner P; Stappenbeck TS; McGovern DP; Keshavarzian A; Mutlu EA; Sauk J; Gevers D; Xavier RJ; Wang D; Parkes M; Virgin HW
[Ad] Endereço:Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO 63110, USA.
[Ti] Título:Disease-specific alterations in the enteric virome in inflammatory bowel disease.
[So] Source:Cell;160(3):447-60, 2015 Jan 29.
[Is] ISSN:1097-4172
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Decreases in the diversity of enteric bacterial populations are observed in patients with Crohn's disease (CD) and ulcerative colitis (UC). Less is known about the virome in these diseases. We show that the enteric virome is abnormal in CD and UC patients. In-depth analysis of preparations enriched for free virions in the intestine revealed that CD and UC were associated with a significant expansion of Caudovirales bacteriophages. The viromes of CD and UC patients were disease and cohort specific. Importantly, it did not appear that expansion and diversification of the enteric virome was secondary to changes in bacterial populations. These data support a model in which changes in the virome may contribute to intestinal inflammation and bacterial dysbiosis. We conclude that the virome is a candidate for contributing to, or being a biomarker for, human inflammatory bowel disease and speculate that the enteric virome may play a role in other diseases.
[Mh] Termos MeSH primário: Caudovirales/isolamento & purificação
Colite Ulcerativa/virologia
Doença de Crohn/virologia
Disbiose/virologia
Microviridae/isolamento & purificação
[Mh] Termos MeSH secundário: Bactérias/classificação
Bactérias/genética
Bactérias/isolamento & purificação
Estudos de Casos e Controles
Caudovirales/genética
Estudos de Coortes
Colite Ulcerativa/microbiologia
Colite Ulcerativa/patologia
Colite Ulcerativa/terapia
Doença de Crohn/microbiologia
Doença de Crohn/patologia
Doença de Crohn/terapia
Disbiose/microbiologia
Disbiose/patologia
Disbiose/terapia
Fezes/microbiologia
Fezes/virologia
Seres Humanos
Metagenoma
Microviridae/genética
[Pt] Tipo de publicação:JOURNAL ARTICLE; MULTICENTER STUDY; RESEARCH SUPPORT, N.I.H., EXTRAMURAL; RESEARCH SUPPORT, NON-U.S. GOV'T; RESEARCH SUPPORT, U.S. GOV'T, P.H.S.
[Em] Mês de entrada:1504
[Cu] Atualização por classe:170220
[Lr] Data última revisão:
170220
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:150127
[St] Status:MEDLINE


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[PMID]:25500185
[Au] Autor:Hulo C; Masson P; Le Mercier P; Toussaint A
[Ad] Endereço:Swiss-Prot Group, Swiss Institute of Bioinformatics, Centre Médical Universitaire, CH-1211 Geneva 4, Switzerland.
[Ti] Título:A structured annotation frame for the transposable phages: a new proposed family "Saltoviridae" within the Caudovirales.
[So] Source:Virology;477:155-63, 2015 Mar.
[Is] ISSN:1096-0341
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Enterobacteriophage Mu is the best studied and paradigm member of the transposable phages. Mu-encoded proteins have been annotated in detail in UniProtKB and linked to a controlled vocabulary describing the various steps involved in the phage lytic and lysogenic cycles. Transposable phages are ubiquitous temperate bacterial viruses with a dsDNA linear genome. Twenty-six of them, that infect α, ß and γ-proteobacteria, have been sequenced. Their conserved properties are described. Based on these characteristics, we propose a reorganization of the Caudovirales, to allow for the inclusion of a "Saltoviridae" family and two newly proposed subfamilies, the "Myosaltovirinae" and "Siphosaltovirinae". The latter could temporarily be included in the existing Myoviridae and Siphoviridae families.
[Mh] Termos MeSH primário: Caudovirales/classificação
Elementos de DNA Transponíveis
Proteobactérias/virologia
Proteínas Virais/genética
[Mh] Termos MeSH secundário: Caudovirales/genética
Anotação de Sequência Molecular
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (DNA Transposable Elements); 0 (Viral Proteins)
[Em] Mês de entrada:1505
[Cu] Atualização por classe:150313
[Lr] Data última revisão:
150313
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:141216
[St] Status:MEDLINE



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