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[PMID]:28283816
[Au] Autor:Shah MS; Ashraf A; Khan MI; Rahman M; Habib M; Chughtai MI; Qureshi JA
[Ad] Endereço:Department of Pathobiology and Veterinary Sciences, University of Connecticut, Storrs, USA. msalahuddin786@hotmail.com.
[Ti] Título:Fowl adenovirus: history, emergence, biology and development of a vaccine against hydropericardium syndrome.
[So] Source:Arch Virol;162(7):1833-1843, 2017 Jul.
[Is] ISSN:1432-8798
[Cp] País de publicação:Austria
[La] Idioma:eng
[Ab] Resumo:The poultry industry has emerged as one of the largest and fastest growing public sectors in the developed and developing countries. Unfortunately, this industry is under a major threat from diseases that are viral (Newcastle disease, infectious bursal disease, influenza, hydropericardium syndrome), bacterial (colibacillosis, pasteurellosis, salmonellosis, mycoplasmosis), parasitic (coccidiosis, histoplasmosis) or nutritional (dyschondroplasia, osteoporosis). Among these diseases, hydropericardium syndrome (HPS) is one of the important emerging diseases occurring in the specific areas of the world where broilers (chickens) are reared under intensive conditions. HPS was first observed in 1987 at Angara Goth, an area near Karachi, Pakistan, where broilers are raised. Since then, HPS has been reported in many countries of the world. From these reported cases, an adenovirus that was either isolated from or visualized electron microscopically in the liver of affected broilers has been implicated in the syndrome. The syndrome has been reproduced by inoculation of isolated fowl adenovirus (FAdV) strains, and hence, the syndrome is also called infectious hydropericardium syndrome. To our knowledge, HPS has not been observed in humans, so it is not considered a zoonotic disease, but it is of economic importance and causes huge losses to the poultry industry. Efforts have been made to develop conventional vaccines against this disease, which were formulated from infected liver homogenate. Formalin-inactivated liver organ vaccines have failed to protect the poultry industry. Hence, there is a dire need to develop a suitable vaccine to combat this disease. Currently, recombinant vaccine candidates are being developed by using molecular biology and biotechnological approaches for the prevention and control of infectious diseases, including HPS. Therefore, it is suggested that the immunogenicity of these recombinant proteins should be evaluated for their use as subunit vaccines.
[Mh] Termos MeSH primário: Infecções por Adenoviridae/veterinária
Adenovirus A das Aves/fisiologia
Doenças das Aves Domésticas/prevenção & controle
Vacinas Virais/imunologia
[Mh] Termos MeSH secundário: Infecções por Adenoviridae/prevenção & controle
Infecções por Adenoviridae/virologia
Animais
Aves Domésticas
Doenças das Aves Domésticas/virologia
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Nm] Nome de substância:
0 (Viral Vaccines)
[Em] Mês de entrada:1707
[Cu] Atualização por classe:170707
[Lr] Data última revisão:
170707
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170312
[St] Status:MEDLINE
[do] DOI:10.1007/s00705-017-3313-5


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[PMID]:27940213
[Au] Autor:Matczuk AK; Niczyporuk JS; Kuczkowski M; Wozniakowski G; Nowak M; Wieliczko A
[Ad] Endereço:Department of Pathology, Division of Microbiology, The Faculty of Veterinary Medicine, Wroclaw University of Environmental and Life Sciences, Norwida Street 31, 50-375 Wroclaw, Poland.
[Ti] Título:Whole genome sequencing of Fowl aviadenovirus A - a causative agent of gizzard erosion and ulceration, in adult laying hens.
[So] Source:Infect Genet Evol;48:47-53, 2017 Mar.
[Is] ISSN:1567-7257
[Cp] País de publicação:Netherlands
[La] Idioma:eng
[Ab] Resumo:Gizzard erosion and ulceration (GEU) caused by fowl aviadenovirus serotype 1 (FAdV-1) of the species Fowl aviadenovirus A (FAdV-A) represents an economically important problem in poultry production. The disease affects mostly young chicken broilers or layers before production. In this study, an unusual GEU outbreak in a flock of laying hens at 38weeks of age is described. The affected flock showed elevated mortality rates, with the highest number of dead birds appearing between the 39th and 40th week of life, with a subsequent reduction in laying performance and decreased total egg weight. Post-mortem examination showed the presence of erosion in multiple areas of the gizzard, with wall perforation in the proximity of the interventriculus. FAdV antibodies were detected in all examined sera with an ELISA assay. The virus was isolated from pathologically altered gizzards. PCR, subsequent sequencing and phylogenetic analysis of the partial hexon gene confirmed the presence of FAdV-A DNA. To investigate the molecular background of FAdV-A which causes GEU in adult hens, whole genome sequencing was performed on two FAdV-A strains - strain W-15, obtained from the outbreak described in this study and strain 61/11z, isolated from a GEU outbreak in 3-week-old broiler chickens in 2011. The genome size of FAdV-A W-15 is 43,849bp. Genome sequence and genome organization resembles those of the reference, apathogenic CELO strain and the newly sequenced GEU strain, 61/11z. Most amino acid changes, between CELO and GEU strains, were observed in ORF0, ORF1, ORF14, IVa2, polymerase, pIIIa, penton base and fiber-2. Analysis conducted on the translated ORFs revealed that W-15 and 61/11z are nearly identical, with the highest rate of amino acid mutations in pTP, 100K, ORF9 and ORF10. In this study, the occurrence of GEU, caused by FAdV-1 infection, in adult layer chickens and the effects of such infection on egg production parameters are described in detail. Moreover, the whole genome sequences of two pathogenic, GEU inducing FAdV-A strains have been provided and characterized for the first time, which in the future will help to pinpoint the viral factors involved in pathogenicity.
[Mh] Termos MeSH primário: Infecções por Adenoviridae/veterinária
Adenovirus A das Aves/genética
Doenças das Aves Domésticas/virologia
Úlcera/veterinária
[Mh] Termos MeSH secundário: Infecções por Adenoviridae/virologia
Animais
Feminino
Genes Virais
Moela das Aves/patologia
Moela das Aves/virologia
Oviposição
Filogenia
Análise de Sequência de DNA
Úlcera/virologia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1711
[Cu] Atualização por classe:171103
[Lr] Data última revisão:
171103
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161213
[St] Status:MEDLINE


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[PMID]:27724044
[Au] Autor:Hess M
[Ad] Endereço:a Clinic for Poultry and Fish Medicine, Department for Farm Animals and Veterinary Public Health , University of Veterinary Medicine , Vienna , Austria.
[Ti] Título:Commensal or pathogen - a challenge to fulfil Koch's Postulates.
[So] Source:Br Poult Sci;58(1):1-12, 2017 Feb.
[Is] ISSN:1466-1799
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:1. Infectious diseases have a large impact on poultry health and economics. Elucidating the pathogenesis of a certain disease is crucial to implement control strategies. 2. Multiplication of a pathogen and its characterisation in vitro are basic requirements to perform experimental studies. However, passaging of the pathogen in vitro can influence the pathogenicity, a process targeted for live vaccine development, but limits the reproduction of clinical signs. 3. Numerous factors can influence the outcome of experimental infections with some importance on the pathogen, application route and host as exemplarily outlined for Histomonas meleagridis, Gallibacterium anatis and fowl aviadenoviruses (FAdVs). 4. In future, more comprehensive and detailed settings are needed to obtain as much information as possible from animal experiments. Processing of samples with modern diagnostic tools provides the option to closely monitor the host-pathogen interaction.
[Mh] Termos MeSH primário: Interações Hospedeiro-Patógeno
Doenças das Aves Domésticas/microbiologia
Simbiose
[Mh] Termos MeSH secundário: Infecções por Adenoviridae/história
Infecções por Adenoviridae/veterinária
Animais
Aviadenovirus/classificação
Galinhas
Inglaterra
Adenovirus A das Aves
História do Século XIX
História do Século XX
História do Século XXI
Pasteurellaceae/classificação
Infecções por Pasteurellaceae/história
Infecções por Pasteurellaceae/microbiologia
Infecções por Pasteurellaceae/veterinária
Doenças das Aves Domésticas/história
Doenças das Aves Domésticas/parasitologia
Infecções Protozoárias em Animais/história
Infecções Protozoárias em Animais/parasitologia
[Pt] Tipo de publicação:BIOGRAPHY; HISTORICAL ARTICLE; LECTURES
[Ps] Nome de pessoa como assunto:Koch R
[Em] Mês de entrada:1702
[Cu] Atualização por classe:170406
[Lr] Data última revisão:
170406
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161012
[St] Status:MEDLINE
[do] DOI:10.1080/00071668.2016.1245849


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[PMID]:27523295
[Au] Autor:Niu X; Chen H; Yang J; Yu X; Ti J; Wang A; Diao Y
[Ad] Endereço:Research Institute of Poultry Disease, Agricultural University of Shan Dong province, Tai'an, Shandong, China.
[Ti] Título:Development of a TaqMan-based real-time PCR assay for the detection of Novel GPV.
[So] Source:J Virol Methods;237:32-37, 2016 Nov.
[Is] ISSN:1879-0984
[Cp] País de publicação:Netherlands
[La] Idioma:eng
[Ab] Resumo:The newly emerged disease, duck beak atrophy and dwarfism syndrome (BADS), is caused by novel goose parovirus (N-GPV). Although N-GPV infection has severe consequences, few methods for detecting this virus have been developed. Therefore, the availability of rapid and reliable molecular diagnostic methods would aid future studies of this novel virus. Clinical specimens from 138 suspected cases of N-GPV infection and 120 cloacal swabs from breeding ducks were used in this study. The targeted sequence of N-GPV cloned into the pMD18-T vector was used to generate the N-GPV DNA standard curve. The specificity of the assay was validated using duck plague virus, GPV, duck hepatitis virus, avian influenza virus, duck reovirus, tembusu virus, and fowl adenovirus. The lowest limit of detection was 8.8×10 copies/µL with a good linear standard curve (Y=-3.3682X+37.220, R =0.9953) over a wide range of input DNA, of which the concentration was between 8.8×10 to 8.8×10 copies/µL. The results show that the real-time PCR assay is a highly sensitive, specific, reproducible, and versatile method for quantitatively detecting N-GPV DNA, and thus can be used to detect this virus, thereby facilitating epidemiological investigations of animals with BADS.
[Mh] Termos MeSH primário: Gansos/virologia
Infecções por Parvoviridae/veterinária
Parvovirus/isolamento & purificação
Doenças das Aves Domésticas/diagnóstico
Reação em Cadeia da Polimerase em Tempo Real/métodos
[Mh] Termos MeSH secundário: Animais
Vírus da Leucose Aviária/genética
Patos/virologia
Adenovirus A das Aves/genética
Vírus da Hepatite do Pato/genética
Limite de Detecção
Orthoreovirus Aviário/genética
Infecções por Parvoviridae/virologia
Parvovirus/genética
Doenças das Aves Domésticas/virologia
Sensibilidade e Especificidade
Proteínas Virais/genética
Proteínas Virais/isolamento & purificação
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Viral Proteins)
[Em] Mês de entrada:1707
[Cu] Atualização por classe:170731
[Lr] Data última revisão:
170731
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160816
[St] Status:MEDLINE


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[PMID]:26629626
[Au] Autor:Dar A; Tipu M; Townsend H; Potter A; Gerdts V; Tikoo S
[Ad] Endereço:Vaccine and Infectious Disease Organization-International Vaccine Centre (VIDO-InterVac), University of Saskatchewan SK, Canada S7N 5E3.
[Ti] Título:Administration of Poly[di(sodium carboxylatoethylphenoxy)phosphazene] (PCEP) and Avian Beta Defensin as Adjuvants in Inactivated Inclusion Body Hepatitis Virus and its Hexon Protein-Based Experimental Vaccine Formulations in Chickens.
[So] Source:Avian Dis;59(4):518-24, 2015 Dec.
[Is] ISSN:0005-2086
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Inclusion body hepatitis (IBH) is one of the major infectious diseases adversely affecting the poultry industry of the United States and Canada. Currently, no effective and safe vaccine is available for the control of IBH virus (IBHV) infection in chickens. However, based on the excellent safety and immunogenic profiles of experimental veterinary vaccines developed with the use of new generation adjuvants, we hypothesized that characterization of vaccine formulations containing inactivated IBHV or its capsid protein hexon as antigens, along with poly[di(sodium carboxylatoethylphenoxy)phosphazene] (PCEP) and avian beta defensin 2 (ABD2) as vaccine adjuvants, will be helpful in development of an effective and safe vaccine formulation for IBH. Our data demonstrated that experimental administration of vaccine formulations containing inactivated IBHV and a mixture of PCEP with or without ABD2 as an adjuvant induced significantly higher antibody responses compared with other vaccine formulations, while hexon protein-based vaccine formulations showed relatively lower levels of antibody responses. Thus, a vaccine formulation containing inactivated IBHV with PCEP or a mixture of PCEP and ABD2 (with a reduced dosage of PCEP) as an adjuvant may serve as a potential vaccine candidate. However, in order to overcome the risks associated with whole virus inactivated vaccines, characterization of additional viral capsid proteins, including fiber protein and penton of IBHV along with hexon protein in combination with more new generation adjuvants, will be helpful in further improvements of vaccines against IBHV infection.
[Mh] Termos MeSH primário: Infecções por Adenoviridae/prevenção & controle
Vacinas contra Adenovirus/imunologia
Adjuvantes Imunológicos/administração & dosagem
Galinhas
Adenovirus A das Aves/imunologia
Hepatite Animal/prevenção & controle
Doenças das Aves Domésticas/prevenção & controle
Vacinas contra Hepatite Viral/imunologia
[Mh] Termos MeSH secundário: Infecções por Adenoviridae/virologia
Vacinas contra Adenovirus/administração & dosagem
Animais
Proteínas do Capsídeo/administração & dosagem
Proteínas do Capsídeo/imunologia
Vírus de Hepatite/imunologia
Hepatite Animal/virologia
Imunidade Inata
Fenilpropionatos/administração & dosagem
Fenilpropionatos/imunologia
Polímeros/administração & dosagem
Doenças das Aves Domésticas/virologia
Proteínas Recombinantes/administração & dosagem
Proteínas Recombinantes/imunologia
Vacinas de Produtos Inativados/administração & dosagem
Vacinas de Produtos Inativados/imunologia
Vacinas contra Hepatite Viral/administração & dosagem
beta-Defensinas/administração & dosagem
beta-Defensinas/imunologia
[Pt] Tipo de publicação:JOURNAL ARTICLE; RANDOMIZED CONTROLLED TRIAL; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (Adenovirus Vaccines); 0 (Adjuvants, Immunologic); 0 (Capsid Proteins); 0 (Phenylpropionates); 0 (Polymers); 0 (Recombinant Proteins); 0 (Vaccines, Inactivated); 0 (Viral Hepatitis Vaccines); 0 (beta-Defensins); 0 (poly(bis(carboxylatoethylphenoxy)phosphazene))
[Em] Mês de entrada:1602
[Cu] Atualização por classe:151203
[Lr] Data última revisão:
151203
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:151203
[St] Status:MEDLINE
[do] DOI:10.1637/11202-052815-Reg.1


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[PMID]:25768948
[Au] Autor:Grafl B; Prokofieva I; Wernsdorf P; Dublecz K; Hess M
[Ad] Endereço:a Department for Farm Animals and Veterinary Public Health , Clinic for Poultry and Fish Medicine, University of Veterinary Medicine , Vienna , Austria.
[Ti] Título:Clinical signs and progression of lesions in the gizzard are not influenced by inclusion of ground oats or whole wheat in the diet following experimental infection with pathogenic fowl adenovirus serotype 1.
[So] Source:Avian Pathol;44(3):230-6, 2015.
[Is] ISSN:1465-3338
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:In the present study the effects of dietary gizzard stimulation on the development and severity of adenoviral gizzard erosion were investigated. For this purpose, specific pathogen-free broilers were divided into six groups, investigating the influence of an oat-containing diet with higher fibre content, a whole wheat-containing diet and a control diet of nearly identical composition, but containing ground wheat. For each feed administered, one group of birds was experimentally infected on the 10th day of age by the oral route with virulent fowl adenovirus serotype 1 (FAdV-1), recently proven to induce gizzard erosions, while the respective negative control groups remained uninfected. Experimental feed was administered from 2 days post-infection onwards. No significant differences on gizzard health or in weight gain could be detected between uninfected control groups or between FAdV-1 infected groups that received different experimental feed. However, independent of the supplied diet, a significantly reduced weight gain was noted from 7 days post-infection onwards in FAdV-1 infected broilers compared to uninfected birds that received the same diet. Macroscopically, discolouration and erosion of the koilin layer and inflammation of the gizzard mucosa were observed in all FAdV-1 infected groups. Histologically, necrosis, degeneration of gizzard epithelial cells and multiple basophilic intranuclear inclusion bodies were observed. In summary, after experimental infection with FAdV-1 development of gizzard erosion in chickens was not influenced by the feeding regimes investigated. Therefore, it is unlikely that dietary gizzard stimulation influences the outcome of adenoviral gizzard erosion in vertically infected broilers.
[Mh] Termos MeSH primário: Infecções por Adenoviridae/veterinária
Galinhas
Adenovirus A das Aves
Moela das Aves/patologia
Doenças das Aves Domésticas/dietoterapia
Doenças das Aves Domésticas/patologia
Doenças das Aves Domésticas/virologia
[Mh] Termos MeSH secundário: Infecções por Adenoviridae/dietoterapia
Infecções por Adenoviridae/patologia
Animais
Anticorpos Antivirais/sangue
Avena
Organismos Livres de Patógenos Específicos
Triticum
Eliminação de Partículas Virais
Grãos Integrais
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (Antibodies, Viral)
[Em] Mês de entrada:1601
[Cu] Atualização por classe:161125
[Lr] Data última revisão:
161125
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:150314
[St] Status:MEDLINE
[do] DOI:10.1080/03079457.2015.1028886


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[PMID]:25685902
[Au] Autor:Joubert HW; Aitchison H; Maartens LH; Venter EH
[Ad] Endereço:Deltamune (Pty) Ltd., Lyttelton. hldjoubert@gmail.com.
[Ti] Título:Molecular differentiation and pathogenicity of Aviadenoviruses isolated during an outbreak of inclusion body hepatitis in South Africa.
[So] Source:J S Afr Vet Assoc;85(1):1058, 2014 Nov 05.
[Is] ISSN:2224-9435
[Cp] País de publicação:South Africa
[La] Idioma:eng
[Ab] Resumo:Fowl adenovirus (FAdV) is a member of the genus Aviadenovirus and causes a number of economically important poultry diseases. One of these diseases, inclusion body hepatitis (IBH), has a worldwide distribution and is characterised by acute mortality (5% - 20%) in production chickens. The disease was first described in the United States of America in 1963 and has also been reported in Canada, the United Kingdom, Australia, France and Ireland, but until now, not in South Africa. Adenoviruses isolated from the first outbreak of IBH in South Africa were able to reproduce the disease in chicken embryo livers. The aim of the present study was to characterise the viruses and determine the pathogenicity of the FAdV strains responsible for the first reported case of IBH in South Africa. Polymerase chain reaction (PCR) amplification of the L1 loop region of the fowl adenovirus hexon gene using degenerate primer pair hexon A/B was used to identify the viruses that were isolated. Restriction fragment length polymorphism (RFLP) of the amplification products was used for the differentiation of 14 isolates of fowl adenovirus. Sequencing of the PCR products followed by amino acid comparison and phylogenetic analysis using the L1 loop region of the hexon protein was done to determine the identity of the isolates. Amino acid sequences of the hexon genes of all the South African isolates were compared with those of reference strains representing FAdV species. Amino acid comparison of 12 South Africa field isolates to FAdV reference strains revealed a high sequence identity (> 93.33%) with reference strains T8-A and 764. Two of the isolates had high sequence identity (93.40%) with reference strains P7-A, C2B and SR48. Phylogenetic analysis of the L1 loop region of the hexon protein of all 14 South African isolates was consistent with their RFLP clusters. The mortality rates of embryos challenged with 106 egg infective doses (EID50) FAdV 2 were 80% - 87% and mortality rates for embryos challenged with 105.95 (EID50) FAdV 8b were 65% - 80%.
[Mh] Termos MeSH primário: Infecções por Adenoviridae/veterinária
Surtos de Doenças/veterinária
Adenovirus A das Aves/isolamento & purificação
Hepatite Viral Animal/virologia
Doenças das Aves Domésticas/virologia
[Mh] Termos MeSH secundário: Infecções por Adenoviridae/epidemiologia
Infecções por Adenoviridae/virologia
Sequência de Aminoácidos
Animais
Embrião de Galinha
Adenovirus A das Aves/patogenicidade
Hepatite Viral Animal/epidemiologia
Hepatite Viral Animal/patologia
Corpos de Inclusão
Nefropatias/patologia
Nefropatias/veterinária
Filogenia
Doenças das Aves Domésticas/epidemiologia
África do Sul/epidemiologia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1510
[Cu] Atualização por classe:150217
[Lr] Data última revisão:
150217
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:150217
[St] Status:MEDLINE
[do] DOI:10.4102/jsava.v85i1.1058


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[PMID]:25649939
[Au] Autor:Huong CT; Murano T; Uno Y; Usui T; Yamaguchi T
[Ad] Endereço:Laboratory of Veterinary Hygiene, Department of Veterinary Medicine, Faculty of Agriculture, Tottori University, Koyama Minami 4-101, Tottori 680-8553, Japan.
[Ti] Título:Molecular detection of avian pathogens in poultry red mite (Dermanyssus gallinae) collected in chicken farms.
[So] Source:J Vet Med Sci;76(12):1583-7, 2014 Dec.
[Is] ISSN:1347-7439
[Cp] País de publicação:Japan
[La] Idioma:eng
[Ab] Resumo:Poultry red mite (PRM, Dermanyssus gallinae) is a blood-sucking ectoparasite as well as a possible vector of several avian pathogens. In this study, to define the role of PRM in the prevalence of avian infectious agents, we used polymerase chain reaction (PCR) to check for the presence of seven pathogens: Avipox virus (APV), Fowl Adenovirus (FAdV), Marek's disease virus (MDV), Erysipelothrix rhusiopathiae (ER), Salmonella enterica (SE), Mycoplasma synoviae (MS) and Mycoplasma gallisepticum (MG). A total of 159 PRM samples collected between 2004 and 2012 from 142 chicken farms in 38 prefectures in Japan were examined. APV DNA was detected in 22 samples (13.8%), 19 of which were wild-type APV. 16S ribosomal RNA (16S rRNA) of MS was detected in 15 samples (9.4%), and the mgc2 gene of MG was detected in 2 samples (1.3%). Eight of 15 MS 16S rRNA sequences differed from the vaccine sequence, indicating they were wild-type strains, while both of the MG mgc2 gene sequences detected were identical to the vaccine sequences. Of these avian pathogen-positive mite samples, three were positive for both wild-types of APV and MS. On the other hand, the DNAs of ER, SE, FAdV and MDV were not detected in any samples. These findings indicated that PRM can harbor the wild-type pathogens and might play a role as a vector in spreading these diseases in farms.
[Mh] Termos MeSH primário: Vetores Aracnídeos/microbiologia
Vetores Aracnídeos/virologia
Galinhas/parasitologia
DNA Bacteriano/isolamento & purificação
DNA Viral/isolamento & purificação
Ácaros/microbiologia
Ácaros/virologia
[Mh] Termos MeSH secundário: Animais
Avipoxvirus/genética
Sequência de Bases
Erysipelothrix/genética
Adenovirus A das Aves/genética
Japão/epidemiologia
Mardivirus/genética
Dados de Sequência Molecular
Mycoplasma gallisepticum/genética
Mycoplasma synoviae/genética
Reação em Cadeia da Polimerase/veterinária
RNA Ribossômico 16S/genética
Salmonella enterica/genética
Análise de Sequência de DNA
Homologia de Sequência
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (DNA, Bacterial); 0 (DNA, Viral); 0 (RNA, Ribosomal, 16S)
[Em] Mês de entrada:1510
[Cu] Atualização por classe:161018
[Lr] Data última revisão:
161018
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:150205
[St] Status:MEDLINE
[do] DOI:10.1292/jvms.14-0253


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[PMID]:25131809
[Au] Autor:Mase M; Nakamura K
[Ad] Endereço:National Institute of Animal Health, 3-1-5 Kannondai, Tsukuba, Ibaraki 305-0856, Japan.
[Ti] Título:Phylogenetic analysis of fowl adenoviruses isolated from chickens with gizzard erosion in Japan.
[So] Source:J Vet Med Sci;76(11):1535-8, 2014 Nov.
[Is] ISSN:1347-7439
[Cp] País de publicação:Japan
[La] Idioma:eng
[Ab] Resumo:Thirty-four fowl adenoviruses (FAdVs) isolated from chickens with gizzard erosion (GE) from 1999 to 2010 were characterized phylogenetically together with foreign isolates. The phylogenetic analysis based on part of the hexon gene classified these 34 FAdV isolates into 3 groups: FAdV-1, -8a and 8b, thereby suggesting that FAdVs associated with GEs in chickens are diverse. All 30 FAdV-1 isolates were genetically identical, and they were also identical with FAdV-1 isolates from GEs in chickens in European countries (Germany, Poland, Austria, Hungary and Italy). Thus, the same type of FAdV-1 has been associated with outbreaks of GE in Japanese chickens for the past 10 years, which may have spread from a common ancestor, although the epidemiological relationship is unknown.
[Mh] Termos MeSH primário: Infecções por Adenoviridae/veterinária
Galinhas
Adenovirus A das Aves/genética
Filogenia
Doenças das Aves Domésticas/virologia
[Mh] Termos MeSH secundário: Infecções por Adenoviridae/patologia
Infecções por Adenoviridae/virologia
Animais
Análise por Conglomerados
Biologia Computacional
Primers do DNA/genética
Adenovirus A das Aves/classificação
Moela das Aves/patologia
Japão
Testes de Neutralização/veterinária
Doenças das Aves Domésticas/patologia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (DNA Primers)
[Em] Mês de entrada:1507
[Cu] Atualização por classe:161125
[Lr] Data última revisão:
161125
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:140819
[St] Status:MEDLINE


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[PMID]:24930982
[Au] Autor:Grafl B; Prokofieva I; Wernsdorf P; Steinborn R; Hess M
[Ad] Endereço:Clinic for Poultry and Fish Medicine, Department for Farm Animals and Veterinary Public Health, University of Veterinary Medicine (Vetmeduni Vienna), Veterinaerplatz 1, A-1210 Vienna, Austria. Electronic address: beatrice.grafl@vetmeduni.ac.at.
[Ti] Título:Infection with an apathogenic fowl adenovirus serotype-1 strain (CELO) prevents adenoviral gizzard erosion in broilers.
[So] Source:Vet Microbiol;172(1-2):177-85, 2014 Aug 06.
[Is] ISSN:1873-2542
[Cp] País de publicação:Netherlands
[La] Idioma:eng
[Ab] Resumo:Gizzard erosion in broilers due to an infection with virulent fowl adenovirus serotype 1 (FAdV-1) is an emerging disease. Although experimental studies were performed, a possible prevention strategy was not reported so far. The present study was set up to determine (i) a possible influence of birds' age at time of inoculation on the pathogenicity of a European FAdV-1 field strain (PA7127), (ii) the virulence of a apathogenic FAdV-1 strain (CELO), and (iii) its capability to protect SPF broilers from adenoviral gizzard erosion caused by the field virus. Oral infection of birds with PA7127 at 1-, 10- and 21-days of life, resulted in reduced weight gain compared to non-infected birds, with significance for birds infected at day-old. Independent of the birds' age at time of inoculation, clinical signs appearing approximately one week after challenge coincided with gizzard lesions. Birds infected exclusively with CELO at the first day of life did not show any clinical signs or pathological changes in the gizzard, confirming the apathogenicity of this European FAdV-1. A similar result was obtained for birds orally infected at the first day of life with CELO and challenged three weeks later with the pathogenic PA7127 strain. Therefore, complete protection of adenoviral gizzard erosion in broilers by vaccination of day-old birds could be demonstrated for the first time, although virus excretion was detected post challenge. Establishment of an amplification refractory mutation system quantitative PCR (ARMS-qPCR) facilitated the identification of the FAdV-1 strain and presence of challenges virus was confirmed in one sample.
[Mh] Termos MeSH primário: Infecções por Adenoviridae/veterinária
Galinhas/virologia
Adenovirus A das Aves/imunologia
Moela das Aves/patologia
Doenças das Aves Domésticas/prevenção & controle
[Mh] Termos MeSH secundário: Infecções por Adenoviridae/imunologia
Infecções por Adenoviridae/patologia
Infecções por Adenoviridae/prevenção & controle
Fatores Etários
Animais
Animais Recém-Nascidos
Galinhas/imunologia
Proteção Cruzada
Adenovirus A das Aves/genética
Adenovirus A das Aves/patogenicidade
Moela das Aves/imunologia
Moela das Aves/virologia
Doenças das Aves Domésticas/imunologia
Doenças das Aves Domésticas/patologia
Virulência
Ganho de Peso
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1410
[Cu] Atualização por classe:161125
[Lr] Data última revisão:
161125
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:140617
[St] Status:MEDLINE



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