Base de dados : MEDLINE
Pesquisa : B04.280.350 [Categoria DeCS]
Referências encontradas : 745 [refinar]
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[PMID]:29209812
[Au] Autor:Bejerman N; Trucco V; de Breuil S; Pardina PR; Lenardon S; Giolitti F
[Ad] Endereço:IPAVE-CIAP-INTA, Av. 11 de Septiembre 4755, 5020, Córdoba, Argentina. nicobejerman@gmail.com.
[Ti] Título:Genome characterization of an Argentinean isolate of alfalfa leaf curl virus.
[So] Source:Arch Virol;163(3):799-803, 2018 Mar.
[Is] ISSN:1432-8798
[Cp] País de publicação:Austria
[La] Idioma:eng
[Ab] Resumo:We investigated the molecular characteristics of an Argentinean isolate of alfalfa leaf curl virus (ALCV-Arg), a virus of the genus Capulavirus in the family Geminiviridae that was isolated from alfalfa plants showing dwarfism. The genome was found to be 2,750 nucleotides in length. In pairwise comparisons, this ALCV isolate shared 83.2% to 92.6% sequence identity with European ALCV isolates. Sequence comparisons and phylogenetic analysis showed that this isolate combines features of strains A and B of ALCV. Recombination analysis showed that ALCV-Arg is a recombinant isolate that was generated by intraspecific recombination between ALCV strains A and B. The results of this study not only show that ALCV-Arg is unique because it combines features of strains A and B but also show that ALCV naturally infects this forage crop on the American continent.
[Mh] Termos MeSH primário: DNA Viral/genética
Geminiviridae/genética
Genoma Viral
Medicago sativa/virologia
Filogenia
Folhas de Planta/virologia
[Mh] Termos MeSH secundário: Argentina
Sequência de Bases
Geminiviridae/classificação
Geminiviridae/isolamento & purificação
Sequenciamento de Nucleotídeos em Larga Escala
Doenças das Plantas/virologia
Recombinação Genética
Análise de Sequência de DNA
Homologia de Sequência do Ácido Nucleico
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (DNA, Viral)
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180220
[Lr] Data última revisão:
180220
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171207
[St] Status:MEDLINE
[do] DOI:10.1007/s00705-017-3673-x


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[PMID]:28476106
[Au] Autor:Silva JCF; Carvalho TFM; Basso MF; Deguchi M; Pereira WA; Sobrinho RR; Vidigal PMP; Brustolini OJB; Silva FF; Dal-Bianco M; Fontes RLF; Santos AA; Zerbini FM; Cerqueira FR; Fontes EPB
[Ad] Endereço:Departamento de Informática, Universidade Federal de Viçosa, Viçosa, Brazil.
[Ti] Título:Geminivirus data warehouse: a database enriched with machine learning approaches.
[So] Source:BMC Bioinformatics;18(1):240, 2017 May 05.
[Is] ISSN:1471-2105
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: The Geminiviridae family encompasses a group of single-stranded DNA viruses with twinned and quasi-isometric virions, which infect a wide range of dicotyledonous and monocotyledonous plants and are responsible for significant economic losses worldwide. Geminiviruses are divided into nine genera, according to their insect vector, host range, genome organization, and phylogeny reconstruction. Using rolling-circle amplification approaches along with high-throughput sequencing technologies, thousands of full-length geminivirus and satellite genome sequences were amplified and have become available in public databases. As a consequence, many important challenges have emerged, namely, how to classify, store, and analyze massive datasets as well as how to extract information or new knowledge. Data mining approaches, mainly supported by machine learning (ML) techniques, are a natural means for high-throughput data analysis in the context of genomics, transcriptomics, proteomics, and metabolomics. RESULTS: Here, we describe the development of a data warehouse enriched with ML approaches, designated geminivirus.org. We implemented search modules, bioinformatics tools, and ML methods to retrieve high precision information, demarcate species, and create classifiers for genera and open reading frames (ORFs) of geminivirus genomes. CONCLUSIONS: The use of data mining techniques such as ETL (Extract, Transform, Load) to feed our database, as well as algorithms based on machine learning for knowledge extraction, allowed us to obtain a database with quality data and suitable tools for bioinformatics analysis. The Geminivirus Data Warehouse (geminivirus.org) offers a simple and user-friendly environment for information retrieval and knowledge discovery related to geminiviruses.
[Mh] Termos MeSH primário: Biologia Computacional/métodos
Bases de Dados Genéticas
Geminiviridae/genética
Aprendizado de Máquina
[Mh] Termos MeSH secundário: Algoritmos
DNA de Cadeia Simples/genética
DNA Viral/genética
Fases de Leitura Aberta/genética
Filogenia
Plantas/virologia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (DNA, Single-Stranded); 0 (DNA, Viral)
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171016
[Lr] Data última revisão:
171016
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170507
[St] Status:MEDLINE
[do] DOI:10.1186/s12859-017-1646-4


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[PMID]:28447216
[Au] Autor:Kemenesi G; Kurucz K; Zana B; Tu VT; Görföl T; Estók P; Földes F; Sztancsik K; Urbán P; Fehér E; Jakab F
[Ad] Endereço:Virological Research Group, Szentágothai Research Centre, University of Pécs, Ifjúság út 20, 7624, Pécs, Hungary.
[Ti] Título:Highly divergent cyclo-like virus in a great roundleaf bat (Hipposideros armiger) in Vietnam.
[So] Source:Arch Virol;162(8):2403-2407, 2017 Aug.
[Is] ISSN:1432-8798
[Cp] País de publicação:Austria
[La] Idioma:eng
[Ab] Resumo:Members of the viral family Circoviridae are increasingly recognized worldwide. Bats seem to be natural reservoirs or dietary-related dispensers of these viruses. Here, we report a distantly related member of the genus Cyclovirus detected in the faeces of a great roundleaf bat (Hipposideros armiger). Interestingly, the novel virus lacks a Circoviridae-specific stem-loop structure, although a Geminiviridae-like nonamer sequence was detected in the large intergenic region. Based on these differences and its phylogenetic position, we propose that our new virus represents a distant and highly divergent member of the genus Cyclovirus. However it is lacking several characteristics of members of the genus, which raises a challenge in its taxonomic classification.
[Mh] Termos MeSH primário: Quirópteros/virologia
Infecções por Circoviridae/veterinária
Circoviridae/genética
Circoviridae/isolamento & purificação
Variação Genética
[Mh] Termos MeSH secundário: Animais
Circoviridae/classificação
Infecções por Circoviridae/epidemiologia
Infecções por Circoviridae/virologia
DNA Intergênico
Reservatórios de Doenças/virologia
Fezes/virologia
Geminiviridae/genética
Filogenia
Vietnã/epidemiologia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (DNA, Intergenic)
[Em] Mês de entrada:1707
[Cu] Atualização por classe:170731
[Lr] Data última revisão:
170731
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170428
[St] Status:MEDLINE
[do] DOI:10.1007/s00705-017-3377-2


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[PMID]:28284245
[Au] Autor:Zerbini FM; Briddon RW; Idris A; Martin DP; Moriones E; Navas-Castillo J; Rivera-Bustamante R; Roumagnac P; Varsani A; Ictv Report Consortium
[Ad] Endereço:1​Departamento de Fitopatologia/Bioagro, Universidade Federal de Viçosa, Viçosa, Minas Gerais 36570-900, Brazil.
[Ti] Título:ICTV Virus Taxonomy Profile: Geminiviridae.
[So] Source:J Gen Virol;98(2):131-133, 2017 Feb.
[Is] ISSN:1465-2099
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:The geminiviruses are a family of small, non-enveloped viruses with single-stranded, circular DNA genomes of 2500-5200 bases. Geminiviruses are transmitted by various types of insect (whiteflies, leafhoppers, treehoppers and aphids). Members of the genus Begomovirus are transmitted by whiteflies, those in the genera Becurtovirus, Curtovirus, Grablovirus, Mastrevirus and Turncurtovirus are transmitted by specific leafhoppers, the single member of the genus Topocuvirus is transmitted by a treehopper and one member of the genus Capulavirus is transmitted by an aphid. Geminiviruses are plant pathogens causing economically important diseases in most tropical and subtropical regions of the world. This is a summary of the International Committee on Taxonomy of Viruses (ICTV) Report on the taxonomy of the Geminiviridae which is available at www.ictv.global/report/geminiviridae.
[Mh] Termos MeSH primário: Geminiviridae/classificação
Doenças das Plantas/virologia
[Mh] Termos MeSH secundário: Animais
Microscopia Crioeletrônica
DNA de Cadeia Simples/química
DNA de Cadeia Simples/genética
DNA Viral/química
DNA Viral/genética
Geminiviridae/genética
Geminiviridae/fisiologia
Geminiviridae/ultraestrutura
Ordem dos Genes
Genoma Viral
Insetos/virologia
Vírion/química
Vírion/genética
Vírion/ultraestrutura
Replicação Viral
Zea mays/virologia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (DNA, Single-Stranded); 0 (DNA, Viral)
[Em] Mês de entrada:1705
[Cu] Atualização por classe:171116
[Lr] Data última revisão:
171116
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170313
[St] Status:MEDLINE
[do] DOI:10.1099/jgv.0.000738


  5 / 745 MEDLINE  
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[PMID]:28283818
[Au] Autor:Susi H; Laine AL; Filloux D; Kraberger S; Farkas K; Bernardo P; Frilander MJ; Martin DP; Varsani A; Roumagnac P
[Ad] Endereço:Department of Biosciences, Metapopulation Research Centre, University of Helsinki, P.O. Box 65, 00014, Helsinki, Finland.
[Ti] Título:Genome sequences of a capulavirus infecting Plantago lanceolata in the Åland archipelago of Finland.
[So] Source:Arch Virol;162(7):2041-2045, 2017 Jul.
[Is] ISSN:1432-8798
[Cp] País de publicação:Austria
[La] Idioma:eng
[Ab] Resumo:The discovery and full-genome sequences of two isolates of a fourth capulavirus species are reported. The viruses were discovered during a viral metagenomics survey of uncultivated Plantago lanceolata plants in the Åland archipelago of south western Finland. The newly discovered viruses apparently produce no symptoms in P. lanceolata. They have a genome organization that is very similar to that of the three known capulavirus species and additionally share between 62.9 and 67.1% genome-wide sequence identity with the isolates of these species. It is therefore proposed that these viruses be assigned to a new capulavirus species named "Plantago lanceolata latent virus".
[Mh] Termos MeSH primário: Geminiviridae/classificação
Doenças das Plantas/virologia
Plantago/virologia
[Mh] Termos MeSH secundário: Finlândia
Geminiviridae/genética
Geminiviridae/isolamento & purificação
Metagenômica
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1708
[Cu] Atualização por classe:170802
[Lr] Data última revisão:
170802
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170312
[St] Status:MEDLINE
[do] DOI:10.1007/s00705-017-3298-0


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[PMID]:28229228
[Au] Autor:Ouattara A; Tiendrébéogo F; Lefeuvre P; Hoareau M; Claverie S; Traoré EV; Barro N; Traoré O; Varsani A; Lett JM
[Ad] Endereço:INERA, 01 BP 476, Ouagadougou, 01, Burkina Faso.
[Ti] Título:New strains of chickpea chlorotic dwarf virus discovered on diseased papaya and tomato plants in Burkina Faso.
[So] Source:Arch Virol;162(6):1791-1794, 2017 Jun.
[Is] ISSN:1432-8798
[Cp] País de publicação:Austria
[La] Idioma:eng
[Ab] Resumo:This is the first description of full genome sequences of chickpea chlorotic dwarf virus (CpCDV; genus Mastrevirus; family Geminiviridae) identified in papaya and tomato plants sampled in Burkina Faso. The CpCDV full genome sequences from papaya and tomato share the highest pairwise sequence identity (84% and 93.5%) with Sudanese isolates of the CpCDV-K and CpCDV-M strains, respectively. Based on the strain demarcation threshold (>94% identity) for mastreviruses, we propose two new strains, CpCDV-Q and CpCDV-R, identified in papaya and tomato, respectively. Phylogenetic analysis confirmed that the sequences belong to a distinct clade of the highly diverse population of CpCDVs. Evidence of inter-strain recombination provided more support for the important role of recombination in CpCDV evolution. The discovery of CpCDV on papaya, a previously unsuspected host, raises many questions about the natural and potential host range of this dicot-infecting mastrevirus species that is reported to be emerging worldwide.
[Mh] Termos MeSH primário: Carica/virologia
Cicer/virologia
Geminiviridae/isolamento & purificação
Doenças das Plantas/virologia
[Mh] Termos MeSH secundário: Sequência de Bases
Burkina Faso
Geminiviridae/classificação
Geminiviridae/genética
Genoma Viral
Dados de Sequência Molecular
Filogenia
RNA Viral/genética
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (RNA, Viral)
[Em] Mês de entrada:1706
[Cu] Atualização por classe:170630
[Lr] Data última revisão:
170630
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170224
[St] Status:MEDLINE
[do] DOI:10.1007/s00705-017-3262-z


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[PMID]:28213872
[Au] Autor:Varsani A; Roumagnac P; Fuchs M; Navas-Castillo J; Moriones E; Idris A; Briddon RW; Rivera-Bustamante R; Murilo Zerbini F; Martin DP
[Ad] Endereço:The Biodesign Center for Fundamental and Applied Microbiomics, Center for Evolution and Medicine and School of Life Sciences, Arizona State University, Tempe, 85287-5001, AZ, USA. arvind.varsani@asu.edu.
[Ti] Título:Capulavirus and Grablovirus: two new genera in the family Geminiviridae.
[So] Source:Arch Virol;162(6):1819-1831, 2017 Jun.
[Is] ISSN:1432-8798
[Cp] País de publicação:Austria
[La] Idioma:eng
[Ab] Resumo:Geminiviruses are plant-infecting single-stranded DNA viruses that occur in most parts of the world. Currently, there are seven genera within the family Geminiviridae (Becurtovirus, Begomovirus, Curtovirus, Eragrovirus, Mastrevirus, Topocuvirus and Turncurtovirus). The rate of discovery of new geminiviruses has increased significantly over the last decade as a result of new molecular tools and approaches (rolling-circle amplification and deep sequencing) that allow for high-throughput workflows. Here, we report the establishment of two new genera: Capulavirus, with four new species (Alfalfa leaf curl virus, Euphorbia caput-medusae latent virus, French bean severe leaf curl virus and Plantago lanceolata latent virus), and Grablovirus, with one new species (Grapevine red blotch virus). The aphid species Aphis craccivora has been shown to be a vector for Alfalfa leaf curl virus, and the treehopper species Spissistilus festinus is the likely vector of Grapevine red blotch virus. In addition, two highly divergent groups of viruses found infecting citrus and mulberry plants have been assigned to the new species Citrus chlorotic dwarf associated virus and Mulberry mosaic dwarf associated virus, respectively. These species have been left unassigned to a genus by the ICTV because their particle morphology and insect vectors are unknown.
[Mh] Termos MeSH primário: Afídeos/virologia
Citrus/virologia
Geminiviridae/isolamento & purificação
Morus/virologia
Doenças das Plantas/virologia
[Mh] Termos MeSH secundário: Animais
Geminiviridae/classificação
Geminiviridae/genética
Insetos Vetores/virologia
Filogenia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1706
[Cu] Atualização por classe:170630
[Lr] Data última revisão:
170630
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170219
[St] Status:MEDLINE
[do] DOI:10.1007/s00705-017-3268-6


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[PMID]:28212430
[Au] Autor:Li F; Zhao N; Li Z; Xu X; Wang Y; Yang X; Liu SS; Wang A; Zhou X
[Ad] Endereço:State Key Laboratory for Biology of Plant Diseases and Insect Pests, Institute of Plant Protection, Chinese Academy of Agricultural Sciences, Beijing, China.
[Ti] Título:A calmodulin-like protein suppresses RNA silencing and promotes geminivirus infection by degrading SGS3 via the autophagy pathway in Nicotiana benthamiana.
[So] Source:PLoS Pathog;13(2):e1006213, 2017 Feb.
[Is] ISSN:1553-7374
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:A recently characterized calmodulin-like protein is an endogenous RNA silencing suppressor that suppresses sense-RNA induced post-transcriptional gene silencing (S-PTGS) and enhances virus infection, but the mechanism underlying calmodulin-like protein-mediated S-PTGS suppression is obscure. Here, we show that a calmodulin-like protein from Nicotiana benthamiana (NbCaM) interacts with Suppressor of Gene Silencing 3 (NbSGS3). Deletion analyses showed that domains essential for the interaction between NbSGS3 and NbCaM are also required for the subcellular localization of NbSGS3 and NbCaM suppressor activity. Overexpression of NbCaM reduced the number of NbSGS3-associated granules by degrading NbSGS3 protein accumulation in the cytoplasm. This NbCaM-mediated NbSGS3 degradation was sensitive to the autophagy inhibitors 3-methyladenine and E64d, and was compromised when key autophagy genes of the phosphatidylinositol 3-kinase (PI3K) complex were knocked down. Meanwhile, silencing of key autophagy genes within the PI3K complex inhibited geminivirus infection. Taken together these data suggest that NbCaM acts as a suppressor of RNA silencing by degrading NbSGS3 through the autophagy pathway.
[Mh] Termos MeSH primário: Calmodulina/metabolismo
Geminiviridae
Regulação da Expressão Gênica de Plantas/fisiologia
Doenças das Plantas/virologia
Tabaco/virologia
[Mh] Termos MeSH secundário: Autofagia
Immunoblotting
Doenças das Plantas/genética
Proteínas de Plantas/metabolismo
Reação em Cadeia da Polimerase
Interferência de RNA/fisiologia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Calmodulin); 0 (Plant Proteins)
[Em] Mês de entrada:1706
[Cu] Atualização por classe:170623
[Lr] Data última revisão:
170623
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170218
[St] Status:MEDLINE
[do] DOI:10.1371/journal.ppat.1006213


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[PMID]:28004232
[Au] Autor:Bozorgi N; Heydarnejad J; Kamali M; Massumi H
[Ad] Endereço:Department of Plant Protection, College of Agriculture, Shahid Bahonar University of Kerman, Kerman, Iran.
[Ti] Título:Splicing features in the expression of the complementary-sense genes of Beet curly top Iran virus.
[So] Source:Virus Genes;53(2):323-327, 2017 Apr.
[Is] ISSN:1572-994X
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Beet curly top Iran virus (BCTIV) is a distinct geminivirus which has been reported from sugar-beet-growing farms in Iran. In this study, the role of the splicing in expression of complementary-sense genes of BCTIV was studied. Total RNA was extracted from BCTIV-infected tissue, and the predicted intron position of complementary-sense mRNA transcripts was amplified by RT-PCR followed by cloning of the amplicons. Sequence confirmed that both spliced and unspliced mRNAs are synthesized by the same transcription unit. Sequence comparison showed that a 155-nt segment (intron) corresponding to nucleotides 1890-2044 of the viral genome has been removed from the latter transcript and therefore fusion of the C1:C2 genes resulted creation of a continuous reading frame for potential production of intact replication initiator protein (Rep). BCTIV intron comprises of most consensus splicing signals required for splicing in eukaryotes and several plant viruses including mastre- and capulaviruses.
[Mh] Termos MeSH primário: Geminiviridae/genética
Filogenia
Processamento de RNA/genética
Proteínas Virais/genética
[Mh] Termos MeSH secundário: Beta vulgaris/virologia
Geminiviridae/patogenicidade
Genoma Viral
Irã (Geográfico)
Dados de Sequência Molecular
Doenças das Plantas/genética
Doenças das Plantas/virologia
Vírion/genética
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Viral Proteins)
[Em] Mês de entrada:1704
[Cu] Atualização por classe:171102
[Lr] Data última revisão:
171102
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161223
[St] Status:MEDLINE
[do] DOI:10.1007/s11262-016-1422-y


  10 / 745 MEDLINE  
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[PMID]:27900587
[Au] Autor:Parizipour MH; Schubert J; Behjatnia SA; Afsharifar A; Habekuß A; Wu B
[Ad] Endereço:Plant Virology Research Center, College of Agriculture, Shiraz University, Shiraz, Iran.
[Ti] Título:Phylogenetic analysis of Wheat dwarf virus isolates from Iran.
[So] Source:Virus Genes;53(2):266-274, 2017 Apr.
[Is] ISSN:1572-994X
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Wheat dwarf virus (WDV) adversely affects cereal production in Asia, Europe, and North Africa. In this study, sequences of several WDV isolates from Iran which is located in the Fertile Crescent were analyzed. Analysis revealed a new geographic cluster for WDV-Wheat from Iran. Recombination analysis demonstrated the existence of several breakpoints in different regions of the viral genome. Data analysis demonstrated that WDV-Barley has an older history and lower diversity than WDV-Wheat. Sequence analysis identified a rare occasion of a co-infection of wheat with WDV-Wheat and WDV-Barley.
[Mh] Termos MeSH primário: Geminiviridae/genética
Genoma Viral/genética
Doenças das Plantas/genética
Triticum/virologia
[Mh] Termos MeSH secundário: Ásia
Europa (Continente)
Geminiviridae/classificação
Geminiviridae/patogenicidade
Variação Genética
Hordeum/genética
Hordeum/virologia
Irã (Geográfico)
Dados de Sequência Molecular
Filogenia
Doenças das Plantas/virologia
Triticum/genética
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1704
[Cu] Atualização por classe:171102
[Lr] Data última revisão:
171102
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161201
[St] Status:MEDLINE
[do] DOI:10.1007/s11262-016-1412-0



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