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Pesquisa : B04.280.375.100 [Categoria DeCS]
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  1 / 20 MEDLINE  
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[PMID]:23411008
[Au] Autor:Piasecki T; Harkins GW; Chrzastek K; Julian L; Martin DP; Varsani A
[Ad] Endereço:Department of Epizootiology with Clinic of Birds and Exotic Animals, Faculty of Veterinary Medicine, Wroclaw University of Environmental and Life Sciences, 50-360 Wroclaw, Poland.
[Ti] Título:Avihepadnavirus diversity in parrots is comparable to that found amongst all other avian species.
[So] Source:Virology;438(2):98-105, 2013 Apr 10.
[Is] ISSN:1096-0341
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Avihepadnaviruses have previously been isolated from various species of duck, goose, stork, heron and crane. Recently the first parrot avihepadnavirus was isolated from a Ring-necked Parakeet in Poland. In this study, 41 psittacine liver samples archived in Poland over the last nine years were tested for presence of Parrot hepatitis B virus (PHBV). We cloned and sequenced PHBV isolates from 18 birds including a Crimson Rosella, an African grey parrot and sixteen Ring-necked Parakeets. PHBV isolates display a degree of diversity (>78% genome wide pairwise identity) that is comparable to that found amongst all other avihepadnaviruses (>79% genome wide pairwise identity). The PHBV viruses can be subdivided into seven genetically distinct groups (tentatively named A-G) of which the two isolated of PHBV-G are the most divergent sharing ∼79% genome wide pairwise identity with all their PHBVs. All PHBV isolates display classical avihepadnavirus genome architecture.
[Mh] Termos MeSH primário: Avihepadnavirus/classificação
Avihepadnavirus/genética
Doenças das Aves/virologia
DNA Viral/genética
Variação Genética
Infecções por Hepadnaviridae/veterinária
Papagaios/virologia
[Mh] Termos MeSH secundário: Animais
Avihepadnavirus/isolamento & purificação
Sequência de Bases
Clonagem Molecular
Genoma Viral
Infecções por Hepadnaviridae/virologia
Periquitos/virologia
Filogenia
Análise de Sequência de DNA
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (DNA, Viral)
[Em] Mês de entrada:1305
[Cu] Atualização por classe:130311
[Lr] Data última revisão:
130311
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:130216
[St] Status:MEDLINE


  2 / 20 MEDLINE  
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[PMID]:22183110
[Au] Autor:Piasecki T; Kurenbach B; Chrzastek K; Bednarek K; Kraberger S; Martin DP; Varsani A
[Ad] Endereço:Department of Epizootiology with Clinic of Birds and Exotic Animals, Faculty of Veterinary Medicine, Wroclaw University of Environmental and Life Sciences, 50-360 Wroclaw, Poland.
[Ti] Título:Molecular characterisation of an avihepadnavirus isolated from Psittacula krameri (ring-necked parrot).
[So] Source:Arch Virol;157(3):585-90, 2012 Mar.
[Is] ISSN:1432-8798
[Cp] País de publicação:Austria
[La] Idioma:eng
[Ab] Resumo:Avihepadnaviruses have been documented previously in ducks, herons, geese, storks and cranes. Here, we describe the full genome of a new avihepadnavirus isolated from Psittacula krameri (ring-necked parrot) in Poland. The parrot hepatitis B virus (PHBV) genome (3042 bp) shares <76% sequence identity with other avihepadnavirus isolates and is phylogenetically most closely related to heron and stork hepatitis B viruses isolates. PHBV has a genome organization similar to that of other hepadnaviruses and contains ORFs for a preC/C, preS/S and polyprotein. Additionally, we identified an X-like ORF in the genome of PHBV. The full-genome data will be useful in developing screening tools for avihepadnaviruses in parrots.
[Mh] Termos MeSH primário: Avihepadnavirus/genética
Avihepadnavirus/isolamento & purificação
DNA Viral/genética
Genoma Viral
Psittacula/virologia
Análise de Sequência de DNA
[Mh] Termos MeSH secundário: Animais
Análise por Conglomerados
Dados de Sequência Molecular
Fases de Leitura Aberta
Filogenia
Polônia
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (DNA, Viral)
[Em] Mês de entrada:1204
[Cu] Atualização por classe:120302
[Lr] Data última revisão:
120302
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:111221
[St] Status:MEDLINE
[do] DOI:10.1007/s00705-011-1197-3


  3 / 20 MEDLINE  
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[PMID]:21850270
[Au] Autor:van Hemert FJ; van de Klundert MA; Lukashov VV; Kootstra NA; Berkhout B; Zaaijer HL
[Ad] Endereço:Laboratory of Experimental Virology, Department of Medical Microbiology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands. f.j.vanhemert@amc.uva.nl
[Ti] Título:Protein X of hepatitis B virus: origin and structure similarity with the central domain of DNA glycosylase.
[So] Source:PLoS One;6(8):e23392, 2011.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Orthohepadnavirus (mammalian hosts) and avihepadnavirus (avian hosts) constitute the family of Hepadnaviridae and differ by their capability and inability for expression of protein X, respectively. Origin and functions of X are unclear. The evolutionary analysis at issue of X indicates that present strains of orthohepadnavirus started to diverge about 25,000 years ago, simultaneously with the onset of avihepadnavirus diversification. These evolutionary events were preceded by a much longer period during which orthohepadnavirus developed a functional protein X while avihepadnavirus evolved without X. An in silico generated 3D-model of orthohepadnaviral X protein displayed considerable similarity to the tertiary structure of DNA glycosylases (key enzymes of base excision DNA repair pathways). Similarity is confined to the central domain of MUG proteins with the typical DNA-binding facilities but without the capability of DNA glycosylase enzymatic activity. The hypothetical translation product of a vestigial X reading frame in the genome of duck hepadnavirus could also been folded into a DNA glycosylase-like 3D-structure. In conclusion, the most recent common ancestor of ortho- and avihepadnavirus carried an X sequence with orthology to the central domain of DNA glycosylase.
[Mh] Termos MeSH primário: DNA Glicosilases/química
DNA Glicosilases/metabolismo
Transativadores/química
Transativadores/metabolismo
[Mh] Termos MeSH secundário: Animais
Avihepadnavirus/enzimologia
DNA Glicosilases/genética
Seres Humanos
Orthohepadnavirus/enzimologia
Estrutura Secundária de Proteína
Transativadores/genética
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Trans-Activators); 0 (hepatitis B virus X protein); EC 3.2.2.- (DNA Glycosylases)
[Em] Mês de entrada:1202
[Cu] Atualização por classe:150204
[Lr] Data última revisão:
150204
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:110819
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0023392


  4 / 20 MEDLINE  
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[PMID]:19057662
[Au] Autor:Dallmeier K; Schultz U; Nassal M
[Ad] Endereço:University Hospital Freiburg, Freiburg, Germany.
[Ti] Título:Heterologous replacement of the supposed host determining region of avihepadnaviruses: high in vivo infectivity despite low infectivity for hepatocytes.
[So] Source:PLoS Pathog;4(12):e1000230, 2008 Dec.
[Is] ISSN:1553-7374
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Hepadnaviruses, including hepatitis B virus (HBV), a highly relevant human pathogen, are small enveloped DNA viruses that replicate via reverse transcription. All hepadnaviruses display a narrow tissue and host tropism. For HBV, this restricts efficient experimental in vivo infection to chimpanzees. While the cellular factors mediating infection are largely unknown, the large viral envelope protein (L) plays a pivotal role for infectivity. Furthermore, certain segments of the PreS domain of L from duck HBV (DHBV) enhanced infectivity for cultured duck hepatocytes of pseudotyped heron HBV (HHBV), a virus unable to infect ducks in vivo. This implied a crucial role for the PreS sequence from amino acid 22 to 90 in the duck tropism of DHBV. Reasoning that reciprocal replacements would reduce infectivity for ducks, we generated spreading-competent chimeric DHBVs with L proteins in which segments 22-90 (Du-He4) or its subsegments 22-37 and 37-90 (Du-He2, Du-He3) are derived from HHBV. Infectivity for duck hepatocytes of Du-He4 and Du-He3, though not Du-He2, was indeed clearly reduced compared to wild-type DHBV. Surprisingly, however, in ducks even Du-He4 caused high-titered, persistent, horizontally and vertically transmissable infections, with kinetics of viral spread similar to those of DHBV when inoculated at doses of 10(8) viral genome equivalents (vge) per animal. Low-dose infections down to 300 vge per duck did not reveal a significant reduction in specific infectivity of the chimera. Hence, sequence alterations in PreS that limited infectivity in vitro did not do so in vivo. These data reveal a much more complex correlation between PreS sequence and host specificity than might have been anticipated; more generally, they question the value of cultured hepatocytes for reliably predicting in vivo infectivity of avian and, by inference, mammalian hepadnaviruses, with potential implications for the risk assessment of vaccine and drug resistant HBV variants.
[Mh] Termos MeSH primário: Avihepadnavirus/genética
Patos/virologia
Vírus da Hepatite B do Pato/genética
Vírus da Hepatite B do Pato/patogenicidade
Hepatite Viral Animal/virologia
Hepatócitos/virologia
[Mh] Termos MeSH secundário: Animais
Anseriformes/virologia
Avihepadnavirus/patogenicidade
Células Cultivadas
Quimera
Infecções por Hepadnaviridae/transmissão
Infecções por Hepadnaviridae/virologia
Hepatite Viral Animal/transmissão
Recombinação Genética
Proteínas do Envelope Viral/genética
Proteínas do Envelope Viral/fisiologia
Vírion/patogenicidade
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (Pre-S protein, Duck hepatitis B virus); 0 (Viral Envelope Proteins)
[Em] Mês de entrada:0903
[Cu] Atualização por classe:140901
[Lr] Data última revisão:
140901
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:081206
[St] Status:MEDLINE
[do] DOI:10.1371/journal.ppat.1000230


  5 / 20 MEDLINE  
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[PMID]:17881436
[Au] Autor:Vorreiter J; Leifer I; Rösler C; Jackevica L; Pumpens P; Nassal M
[Ad] Endereço:University Hospital Freiburg, Internal Medicine 2/Molecular Biology, Hugstetter Str. 55, D-79106 Freiburg, Germany.
[Ti] Título:Monoclonal antibodies providing topological information on the duck hepatitis B virus core protein and avihepadnaviral nucleocapsid structure.
[So] Source:J Virol;81(23):13230-4, 2007 Dec.
[Is] ISSN:1098-5514
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:The icosahedral capsid of duck hepatitis B virus (DHBV) is formed by a single core protein species (DHBc). DHBc is much larger than HBc from human HBV, and no high-resolution structure is available. In an accompanying study (M. Nassal, I. Leifer, I. Wingert, K. Dallmeier, S. Prinz, and J. Vorreiter, J. Virol. 81:13218-13229, 2007), we used extensive mutagenesis to derive a structural model for DHBc. For independent validation, we here mapped the epitopes of seven anti-DHBc monoclonal antibodies. Using numerous recombinant DHBc proteins and authentic nucleocapsids from different avihepadnaviruses as test antigens, plus a panel of complementary assays, particle-specific and exposed plus buried linear epitopes were revealed. These data fully support key features of the model.
[Mh] Termos MeSH primário: Avihepadnavirus/química
Vírus da Hepatite B do Pato/química
Nucleocapsídeo/química
Proteínas do Core Viral/química
[Mh] Termos MeSH secundário: Anticorpos Monoclonais/metabolismo
Anticorpos Antivirais/metabolismo
Avihepadnavirus/imunologia
Mapeamento de Epitopos
Epitopos/imunologia
Vírus da Hepatite B do Pato/imunologia
Modelos Moleculares
Nucleocapsídeo/imunologia
Estrutura Terciária de Proteína
Proteínas do Core Viral/imunologia
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (Antibodies, Monoclonal); 0 (Antibodies, Viral); 0 (Epitopes); 0 (Viral Core Proteins)
[Em] Mês de entrada:0712
[Cu] Atualização por classe:140904
[Lr] Data última revisão:
140904
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:070921
[St] Status:MEDLINE


  6 / 20 MEDLINE  
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[PMID]:17854046
[Au] Autor:Yang J; Xi Q; Deng R; Wang J; Hou J; Wang X
[Ad] Endereço:Department of Infectious Diseases, Nanfang Hospital, Southern Medical University, Guangzhou, People's Republic of China.
[Ti] Título:Identification of interspecies recombination among hepadnaviruses infecting cross-species hosts.
[So] Source:J Med Virol;79(11):1741-50, 2007 Nov.
[Is] ISSN:0146-6615
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Members of the family Hepadnaviridae are divided into two genera, Orthohepadnavirus (from mammalian) and Avihepadnavirus (from avian). Recombination had been found to occur among human hepatitis B virus (HBV) strains of different genotypes, or between hepadnavirus strains from human and nonhuman primate. To reach a comparatively complete inspection of interspecies recombination events among hepadnavirus strains from various hosts, 837 hepadnavirus complete genome sequences from human and 112 from animals were analyzed by using fragment typing to scan for potential interspecies recombinants. Further bootscanning and phylogenetic analyses of the potential recombinants revealed six genome sequences as interspecies recombinants. Interspecies recombination events were found to occur among HBV strains from human and nonhuman primates, from gibbons of different genera, from chimpanzee and an unknown host, and between two avian hepadnavirus strains from birds of different subfamilies, which was identified for the first time. HBV interspecies recombinants were found to have recombination hot spots similar to that of human HBV intergenotype recombinants, breakpoints frequently locating near gene boundaries. Interspecies recombination found in this study may alter current views on hepadnavirus host specificity.
[Mh] Termos MeSH primário: Hepadnaviridae/classificação
Hepadnaviridae/genética
Hepatite Viral Animal/virologia
Hepatite Viral Humana/virologia
Recombinação Genética
[Mh] Termos MeSH secundário: Animais
Avihepadnavirus/classificação
Avihepadnavirus/genética
Genoma Viral
Genótipo
Hepadnaviridae/isolamento & purificação
Seres Humanos
Dados de Sequência Molecular
Orthohepadnavirus/classificação
Orthohepadnavirus/genética
Filogenia
Análise de Sequência de DNA
Especificidade da Espécie
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Em] Mês de entrada:0710
[Cu] Atualização por classe:070919
[Lr] Data última revisão:
070919
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:070915
[St] Status:MEDLINE


  7 / 20 MEDLINE  
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[PMID]:17430968
[Au] Autor:Girard FC; Ottink OM; Ampt KA; Tessari M; Wijmenga SS
[Ad] Endereço:Department of Physical Chemistry/Biophysical Chemistry, Radboud University, Toernooiveld 1 6525 ED Nijmegen, The Netherlands.
[Ti] Título:Thermodynamics and NMR studies on Duck, Heron and Human HBV encapsidation signals.
[So] Source:Nucleic Acids Res;35(8):2800-11, 2007.
[Is] ISSN:1362-4962
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Hepatitis B virus (HBV) replication is initiated by binding of its reverse transcriptase (P) to the apical stem-loop (AL) and primer loop (PL) of epsilon, a highly conserved RNA element at the 5'-end of the RNA pregenome. Mutation studies on duck/heron and human in vitro systems have shown similarities but also differences between their P-epsilon interaction. Here, NMR and UV thermodynamic data on AL (and PL) from these three species are presented. The stabilities of the duck and heron ALs were found to be similar, and much lower than that of human. NMR data show that this low stability stems from an 11-nt internal bulge destabilizing the stem of heron AL. In duck, although structured at low temperature, this region also forms a weak point as its imino resonances broaden to disappearance between 30 and 35 degrees C well below the overall AL melting temperature. Surprisingly, the duck- and heron ALs were both found to be capped by a stable well-structured UGUU tetraloop. All avian ALs are expected to adhere to this because of their conserved sequence. Duck PL is stable and structured and, in view of sequence similarities, the same is expected for heron - and human PL.
[Mh] Termos MeSH primário: Avihepadnavirus/genética
Vírus da Hepatite B do Pato/genética
Vírus da Hepatite B/genética
RNA Viral/química
Termodinâmica
[Mh] Termos MeSH secundário: Sequência de Bases
Capsídeo/química
Dados de Sequência Molecular
Ressonância Magnética Nuclear Biomolecular
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (RNA, Viral)
[Em] Mês de entrada:0706
[Cu] Atualização por classe:170219
[Lr] Data última revisão:
170219
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:070414
[St] Status:MEDLINE


  8 / 20 MEDLINE  
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[PMID]:17206758
[Au] Autor:Funk A; Mhamdi M; Will H; Sirma H
[Ad] Endereço:Department of General Virology, Heinrich-Pette-Institut fur experimentelle Virologie und Immunologie an der Universitat Hamburg, PO Box 201652, Hamburg 20206, Germany.
[Ti] Título:Avian hepatitis B viruses: molecular and cellular biology, phylogenesis, and host tropism.
[So] Source:World J Gastroenterol;13(1):91-103, 2007 Jan 07.
[Is] ISSN:1007-9327
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:The human hepatitis B virus (HBV) and the duck hepatitis B virus (DHBV) share several fundamental features. Both viruses have a partially double-stranded DNA genome that is replicated via a RNA intermediate and the coding open reading frames (ORFs) overlap extensively. In addition, the genomic and structural organization, as well as replication and biological characteristics, are very similar in both viruses. Most of the key features of hepadnaviral infection were first discovered in the DHBV model system and subsequently confirmed for HBV. There are, however, several differences between human HBV and DHBV. This review will focus on the molecular and cellular biology, evolution, and host adaptation of the avian hepatitis B viruses with particular emphasis on DHBV as a model system.
[Mh] Termos MeSH primário: Avihepadnavirus/genética
Avihepadnavirus/fisiologia
Infecções por Hepadnaviridae/patologia
[Mh] Termos MeSH secundário: Sequência de Aminoácidos
Animais
Avihepadnavirus/crescimento & desenvolvimento
Avihepadnavirus/patogenicidade
DNA Viral/genética
Modelos Animais de Doenças
Patos
Infecções por Hepadnaviridae/tratamento farmacológico
Infecções por Hepadnaviridae/fisiopatologia
Vírus da Hepatite B do Pato/genética
Vírus da Hepatite B do Pato/crescimento & desenvolvimento
Vírus da Hepatite B do Pato/patogenicidade
Vírus da Hepatite B do Pato/fisiologia
Dados de Sequência Molecular
Morfogênese/fisiologia
Tropismo/fisiologia
Proteínas Virais/análise
Proteínas Virais/fisiologia
Vacinas Virais/genética
Vacinas Virais/uso terapêutico
Internalização do Vírus
Replicação Viral/fisiologia
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T; REVIEW
[Nm] Nome de substância:
0 (DNA, Viral); 0 (Viral Proteins); 0 (Viral Vaccines)
[Em] Mês de entrada:0703
[Cu] Atualização por classe:151022
[Lr] Data última revisão:
151022
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:070109
[St] Status:MEDLINE


  9 / 20 MEDLINE  
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[PMID]:17206751
[Au] Autor:Schaefer S
[Ad] Endereço:Abteilung für Virologie, Institut für Medizinische Mikrobiologie, Virologie und Hygiene, Universität Rostock, Schillingallee 70, D-18057 Rostock, Germany. stephan.schaefer@med.uni-rostock.de
[Ti] Título:Hepatitis B virus taxonomy and hepatitis B virus genotypes.
[So] Source:World J Gastroenterol;13(1):14-21, 2007 Jan 07.
[Is] ISSN:1007-9327
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Hepatitis B virus (HBV) is a member of the hepadnavirus family. Hepadnaviruses can be found in both mammals (orthohepadnaviruses) and birds (avihepadnaviruses). The genetic variability of HBV is very high. There are eight genotypes of HBV and three clades of HBV isolates from apes that appear to be additional genotypes of HBV. Most genotypes are now divided into subgenotypes with distinct virological and epidemiological properties. In addition, recombination among HBV genotypes increases the variability of HBV. This review summarises current knowledge of the epidemiology of genetic variability in hepadnaviruses and, due to rapid progress in the field, updates several recent reviews on HBV genotypes and subgenotypes.
[Mh] Termos MeSH primário: Vírus da Hepatite B/classificação
Vírus da Hepatite B/genética
Filogenia
[Mh] Termos MeSH secundário: Animais
Avihepadnavirus/classificação
Avihepadnavirus/genética
DNA Recombinante/genética
DNA Viral/genética
Genótipo
Hepatite B/epidemiologia
Vírus da Hepatite B/isolamento & purificação
Seres Humanos
Orthohepadnavirus/classificação
Orthohepadnavirus/genética
Prevalência
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Nm] Nome de substância:
0 (DNA, Recombinant); 0 (DNA, Viral)
[Em] Mês de entrada:0703
[Cu] Atualização por classe:170219
[Lr] Data última revisão:
170219
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:070109
[St] Status:MEDLINE


  10 / 20 MEDLINE  
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[PMID]:15831944
[Au] Autor:Lin L; Prassolov A; Funk A; Quinn L; Hohenberg H; Frölich K; Newbold J; Ludwig A; Will H; Sirma H; Steinbach F
[Ad] Endereço:Heinrich-Pette-Institut für Experimentelle Virologie und Immunologie an der Universität Hamburg, PO Box 201652, 20206 Hamburg, Germany.
[Ti] Título:Evidence from nature: interspecies spread of heron hepatitis B viruses.
[So] Source:J Gen Virol;86(Pt 5):1335-42, 2005 May.
[Is] ISSN:0022-1317
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Heron hepatitis B viruses (HHBVs) in three subspecies of free-living great blue herons (Ardea herodias) from Florida, USA, were identified and characterized. Eight of 13 samples were positive in all assays used, whereas sera from egrets, which are also members of the family Ardeidae, were negative in the same assays. Comparative phylogenetic analysis of viral DNA sequences from the preS/S region of previously reported and novel HHBV strains isolated from captive grey herons (Germany) and free-ranging great blue herons (USA), respectively, revealed a strong conservation (95 % sequence similarity) with two separate clusters, implying a common ancestor of all strains. Our data demonstrate for the first time that different subspecies of herons are infected by HHBV and that these infections exist in non-captive birds. Phylogenetic analysis and the fact that the different heron species are geographically isolated populations suggest that lateral transmission, virus adaptation and environmental factors all play a role in HHBV spreading and evolution.
[Mh] Termos MeSH primário: Avihepadnavirus
Avihepadnavirus/isolamento & purificação
Doenças das Aves/transmissão
Aves/virologia
Infecções por Hepadnaviridae/veterinária
[Mh] Termos MeSH secundário: Animais
Avihepadnavirus/genética
Sequência de Bases
Doenças das Aves/virologia
DNA Viral/química
DNA Viral/isolamento & purificação
Transmissão de Doença Infecciosa
Infecções por Hepadnaviridae/transmissão
Infecções por Hepadnaviridae/virologia
Dados de Sequência Molecular
Filogenia
Alinhamento de Sequência
Análise de Sequência de DNA
Homologia de Sequência
Proteínas do Envelope Viral/genética
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (DNA, Viral); 0 (S envelope protein, hepatitis B virus); 0 (Viral Envelope Proteins)
[Em] Mês de entrada:0505
[Cu] Atualização por classe:081121
[Lr] Data última revisão:
081121
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:050416
[St] Status:MEDLINE



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