Base de dados : MEDLINE
Pesquisa : B04.280.950 [Categoria DeCS]
Referências encontradas : 8 [refinar]
Mostrando: 1 .. 8   no formato [Detalhado]

página 1 de 1

  1 / 8 MEDLINE  
              next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:28759330
[Au] Autor:Colson P; La Scola B; Raoult D
[Ad] Endereço:Unité de Recherche sur les Maladies Infectieuses et Tropicales Emergentes (URMITE), Aix Marseille Université, UM63, CNRS 7278, IRD 198, INSERM 1095, Institut Hospitalo-Universitaire (IHU) Méditerranée Infection, Assistance Publique-Hôpitaux de Marseille (AP-HM), 13005 Marseille, France; email: didier.raoult@gmail.com.
[Ti] Título:Giant Viruses of Amoebae: A Journey Through Innovative Research and Paradigm Changes.
[So] Source:Annu Rev Virol;4(1):61-85, 2017 Sep 29.
[Is] ISSN:2327-0578
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Giant viruses of amoebae were discovered serendipitously in 2003; they are visible via optical microscopy, making them bona fide microbes. Their lifestyle, structure, and genomes break the mold of classical viruses. Giant viruses of amoebae are complex microorganisms. Their genomes harbor between 444 and 2,544 genes, including many that are unique to viruses, and encode translation components; their virions contain >100 proteins as well as mRNAs. Mimiviruses have a specific mobilome, including virophages, provirophages, and transpovirons, and can resist virophages through a system known as MIMIVIRE (mimivirus virophage resistance element). Giant viruses of amoebae bring upheaval to the definition of viruses and tend to separate the current virosphere into two categories: very simple viruses and viruses with complexity similar to that of other microbes. This new paradigm is propitious for enhanced detection and characterization of giant viruses of amoebae, and a particular focus on their role in humans is warranted.
[Mh] Termos MeSH primário: Amoeba/virologia
Genoma Viral
Vírus Gigantes/genética
Vírus Gigantes/fisiologia
[Mh] Termos MeSH secundário: DNA Viral
Vírus Gigantes/classificação
Vírus Gigantes/isolamento & purificação
Interações Hospedeiro-Patógeno
Mimiviridae/genética
Filogenia
Vírion/genética
Virófagos/genética
Virófagos/fisiologia
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Nm] Nome de substância:
0 (DNA, Viral)
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171027
[Lr] Data última revisão:
171027
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170801
[St] Status:MEDLINE
[do] DOI:10.1146/annurev-virology-101416-041816


  2 / 8 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:28239153
[Au] Autor:Colson P; La Scola B; Levasseur A; Caetano-Anollés G; Raoult D
[Ad] Endereço:Unité de Recherche sur les Maladies Infectieuses et Tropicales Emergentes (URMITE), Aix-Marseille University, UM63, CNRS 7278, IRD 198, INSERM 1095, Institut Hospitalo-Universitaire (IHU) - Méditerranée Infection, AP-HM, 19-21 Boulevard Jean Moulin, 13385 Marseille, France.
[Ti] Título:Mimivirus: leading the way in the discovery of giant viruses of amoebae.
[So] Source:Nat Rev Microbiol;15(4):243-254, 2017 Apr.
[Is] ISSN:1740-1534
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:The accidental discovery of the giant virus of amoeba - Acanthamoeba polyphaga mimivirus (APMV; more commonly known as mimivirus) - in 2003 changed the field of virology. Viruses were previously defined by their submicroscopic size, which probably prevented the search for giant viruses, which are visible by light microscopy. Extended studies of giant viruses of amoebae revealed that they have genetic, proteomic and structural complexities that were not thought to exist among viruses and that are comparable to those of bacteria, archaea and small eukaryotes. The giant virus particles contain mRNA and more than 100 proteins, they have gene repertoires that are broader than those of other viruses and, notably, some encode translation components. The infection cycles of giant viruses of amoebae involve virus entry by amoebal phagocytosis and replication in viral factories. In addition, mimiviruses are infected by virophages, defend against them through the mimivirus virophage resistance element (MIMIVIRE) system and have a unique mobilome. Overall, giant viruses of amoebae, including mimiviruses, marseilleviruses, pandoraviruses, pithoviruses, faustoviruses and molliviruses, challenge the definition and classification of viruses, and have increasingly been detected in humans.
[Mh] Termos MeSH primário: Acanthamoeba/virologia
Amoeba/virologia
Vírus Gigantes/ultraestrutura
Mimiviridae/ultraestrutura
[Mh] Termos MeSH secundário: Genoma Viral/genética
Vírus Gigantes/genética
Vírus Gigantes/metabolismo
Mimiviridae/genética
Mimiviridae/metabolismo
Virófagos/genética
Internalização do Vírus
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Em] Mês de entrada:1705
[Cu] Atualização por classe:170523
[Lr] Data última revisão:
170523
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170228
[St] Status:MEDLINE
[do] DOI:10.1038/nrmicro.2016.197


  3 / 8 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:27929021
[Au] Autor:Fischer MG; Hackl T
[Ad] Endereço:Department of Biomolecular Mechanisms, Max Planck Institute for Medical Research, 69120 Heidelberg, Germany.
[Ti] Título:Host genome integration and giant virus-induced reactivation of the virophage mavirus.
[So] Source:Nature;540(7632):288-291, 2016 12 07.
[Is] ISSN:1476-4687
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Endogenous viral elements are increasingly found in eukaryotic genomes, yet little is known about their origins, dynamics, or function. Here we provide a compelling example of a DNA virus that readily integrates into a eukaryotic genome where it acts as an inducible antiviral defence system. We found that the virophage mavirus, a parasite of the giant Cafeteria roenbergensis virus (CroV), integrates at multiple sites within the nuclear genome of the marine protozoan Cafeteria roenbergensis. The endogenous mavirus is structurally and genetically similar to eukaryotic DNA transposons and endogenous viruses of the Maverick/Polinton family. Provirophage genes are not constitutively expressed, but are specifically activated by superinfection with CroV, which induces the production of infectious mavirus particles. Virophages can inhibit the replication of mimivirus-like giant viruses and an anti-viral protective effect of provirophages on their hosts has been hypothesized. We find that provirophage-carrying cells are not directly protected from CroV; however, lysis of these cells releases infectious mavirus particles that are then able to suppress CroV replication and enhance host survival during subsequent rounds of infection. The microbial host-parasite interaction described here involves an altruistic aspect and suggests that giant-virus-induced activation of provirophages might be ecologically relevant in natural protist populations.
[Mh] Termos MeSH primário: Genoma/genética
Vírus Gigantes/fisiologia
Interações Hospedeiro-Parasita
Estramenópilas/genética
Estramenópilas/virologia
Virófagos/crescimento & desenvolvimento
Integração Viral
[Mh] Termos MeSH secundário: Elementos de DNA Transponíveis/genética
Regulação Viral da Expressão Gênica
Genoma Viral/genética
Vírus Gigantes/genética
Vírus Gigantes/crescimento & desenvolvimento
Mimiviridae/crescimento & desenvolvimento
Prófagos/genética
Prófagos/fisiologia
Estramenópilas/crescimento & desenvolvimento
Superinfecção
Vírion/crescimento & desenvolvimento
Virófagos/genética
Liberação de Vírus
Replicação Viral
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (DNA Transposable Elements)
[Em] Mês de entrada:1703
[Cu] Atualização por classe:170323
[Lr] Data última revisão:
170323
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161209
[St] Status:MEDLINE
[do] DOI:10.1038/nature20593


  4 / 8 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
[PMID]:27886075
[Au] Autor:Bekliz M; Colson P; La Scola B
[Ad] Endereço:Aix-Marseille University, URMITE UM 63 CNRS 7278 IRD 198 INSERM U1905, 27 Boulevard Jean Moulin, 13385 Marseille CEDEX 05, France. meriembekliz@hotmail.com.
[Ti] Título:The Expanding Family of Virophages.
[So] Source:Viruses;8(11), 2016 Nov 23.
[Is] ISSN:1999-4915
[Cp] País de publicação:Switzerland
[La] Idioma:eng
[Ab] Resumo:Virophages replicate with giant viruses in the same eukaryotic cells. They are a major component of the specific mobilome of mimiviruses. Since their discovery in 2008, five other representatives have been isolated, 18 new genomes have been described, two of which being nearly completely sequenced, and they have been classified in a new viral family, . Virophages are small viruses with approximately 35-74 nm large icosahedral capsids and 17-29 kbp large double-stranded DNA genomes with 16-34 genes, among which a very small set is shared with giant viruses. Virophages have been isolated or detected in various locations and in a broad range of habitats worldwide, including the deep ocean and inland. Humans, therefore, could be commonly exposed to virophages, although currently limited evidence exists of their presence in humans based on serology and metagenomics. The distribution of virophages, the consequences of their infection and the interactions with their giant viral hosts within eukaryotic cells deserve further research.
[Mh] Termos MeSH primário: Mimiviridae/classificação
Mimiviridae/isolamento & purificação
Virófagos/classificação
Virófagos/isolamento & purificação
[Mh] Termos MeSH secundário: DNA Viral/genética
Eucariotos/virologia
Mimiviridae/ultraestrutura
Vírion/ultraestrutura
Virófagos/genética
Virófagos/ultraestrutura
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Nm] Nome de substância:
0 (DNA, Viral)
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170913
[Lr] Data última revisão:
170913
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161126
[St] Status:MEDLINE


  5 / 8 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
[PMID]:27758740
[Au] Autor:Bekliz M; Levasseur A; La Scola B; Raoult D
[Ad] Endereço:Aix-Marseille Université, Unité de recherche sur les maladies infectieuses et tropicales émergentes (URMITE), UM63, CNRS 7278, IRD 198, Inserm U1095, IHU Méditerranée Infection, Pôle des Maladies Infectieuses, Assistance Publique-Hôpitaux de Marseille, Faculté de médecine, 27, boulevard Jean Moulin,
[Ti] Título:[The defence system MIMIVIRE in mimivirus illustrates Red Queen hypothesis].
[Ti] Título:MIMIVIRE, un système de défense chez mimivirus qui illustre l'hypothèse de la Reine Rouge..
[So] Source:Med Sci (Paris);32(10):818-819, 2016 Oct.
[Is] ISSN:1958-5381
[Cp] País de publicação:France
[La] Idioma:fre
[Mh] Termos MeSH primário: Mimiviridae/genética
Mimiviridae/fisiologia
[Mh] Termos MeSH secundário: Imunidade Adaptativa
Sequência de Bases
Sistemas CRISPR-Cas
DNA Viral/química
Evolução Molecular
Genoma Viral
Mimiviridae/classificação
Modelos Biológicos
Virófagos
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (DNA, Viral)
[Em] Mês de entrada:1705
[Cu] Atualização por classe:170530
[Lr] Data última revisão:
170530
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161021
[St] Status:MEDLINE


  6 / 8 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:27315813
[Au] Autor:Claverie JM; Abergel C
[Ad] Endereço:Structural and Genomic Information Laboratory (UMR7256), CNRS Aix Marseille University, Mediterranean Institute of Microbiology (FR 3479), Marseille, France. Jean-Michel.Claverie@univ-amu.fr.
[Ti] Título:CRISPR-Cas-like system in giant viruses: why MIMIVIRE is not likely to be an adaptive immune system.
[So] Source:Virol Sin;31(3):193-6, 2016 Jun.
[Is] ISSN:1995-820X
[Cp] País de publicação:China
[La] Idioma:eng
[Mh] Termos MeSH primário: Sistemas CRISPR-Cas/fisiologia
Repetições Palindrômicas Curtas Agrupadas e Regularmente Espaçadas/imunologia
Vírus Gigantes/imunologia
Mimiviridae/imunologia
[Mh] Termos MeSH secundário: Acanthamoeba/virologia
Imunidade Adaptativa
Sequência de Aminoácidos
Sequência de Bases
Sistemas CRISPR-Cas/genética
Evolução Molecular
Vírus Gigantes/genética
Vírus Gigantes/fisiologia
Interações Hospedeiro-Patógeno
Sistema Imunitário
Mimiviridae/genética
Mimiviridae/fisiologia
Proteínas Virais/genética
Proteínas Virais/imunologia
Virófagos/genética
Virófagos/imunologia
Fenômenos Fisiológicos Virais
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Viral Proteins)
[Em] Mês de entrada:1704
[Cu] Atualização por classe:171109
[Lr] Data última revisão:
171109
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160619
[St] Status:MEDLINE
[do] DOI:10.1007/s12250-016-3801-x


  7 / 8 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
PubMed Central Texto completo
Texto completo
[PMID]:27151658
[Au] Autor:Oh S; Yoo D; Liu WT
[Ad] Endereço:School of Civil and Environmental Engineerin, Nanyang Technological University.
[Ti] Título:Metagenomics Reveals a Novel Virophage Population in a Tibetan Mountain Lake.
[So] Source:Microbes Environ;31(2):173-7, 2016 Jun 25.
[Is] ISSN:1347-4405
[Cp] País de publicação:Japan
[La] Idioma:eng
[Ab] Resumo:Virophages are parasites of giant viruses that infect eukaryotic organisms and may affect the ecology of inland water ecosystems. Despite the potential ecological impact, limited information is available on the distribution, diversity, and hosts of virophages in ecosystems. Metagenomics revealed that virophages were widely distributed in inland waters with various environmental characteristics including salinity and nutrient availability. A novel virophage population was overrepresented in a planktonic microbial community of the Tibetan mountain lake, Lake Qinghai. Our study identified coccolithophores and coccolithovirus-like phycodnaviruses in the same community, which may serve as eukaryotic and viral hosts of the virophage population, respectively.
[Mh] Termos MeSH primário: Lagos/microbiologia
Virófagos/classificação
Virófagos/isolamento & purificação
[Mh] Termos MeSH secundário: Genoma Viral
Metagenômica
Filogenia
Análise de Sequência de DNA
Tibet
Virófagos/genética
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1703
[Cu] Atualização por classe:170330
[Lr] Data última revisão:
170330
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160507
[St] Status:MEDLINE
[do] DOI:10.1264/jsme2.ME16003


  8 / 8 MEDLINE  
              first record previous record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:27088734
[Au] Autor:Villain A; Gallot-Lavallée L; Blanc G; Maumus F
[Ad] Endereço:Laboratoire Information Génomique & Structurale, UMR7256 (IMM FR3479) CNRS Aix-Marseille Université, 163 Avenue de Luminy, Case 934, 13288 Marseille Cedex 9, France.
[Ti] Título:Giant viruses at the core of microscopic wars with global impacts.
[So] Source:Curr Opin Virol;17:130-7, 2016 Apr.
[Is] ISSN:1879-6265
[Cp] País de publicação:Netherlands
[La] Idioma:eng
[Ab] Resumo:The unicellular eukaryotes (also called protists) that inhabit the contemporary oceans have large impacts on major biogeochemical cycles. Populations of oceanic protists are to a large extent regulated by their viral parasites, especially nucleocytoplasmic large DNA viruses (NCLDVs). NCLDVs can themselves be the prey of smaller viruses called virophages and can also be infected by transposable elements termed transpovirons. These entangled parasitisms have fostered the emergence of sophisticated infection and defence strategies. In addition persistent contact has facilitated the exchange of genes between different parties. Recent advances shed light on the strategies that govern such microbial wars. Endogenous virophage-like elements found in the genome of a marine alga could for instance provide the host acquired immunity against NCLDVs. In return, it was recently speculated that virophage sequences can be hijacked by NCLDVs and used as genetic weapons against virophages.
[Mh] Termos MeSH primário: Vírus de DNA/fisiologia
Eucariotos/virologia
Evolução Molecular
Vírus Gigantes/fisiologia
Virófagos/fisiologia
[Mh] Termos MeSH secundário: Vírus de DNA/genética
DNA Viral/genética
Genoma Viral
Vírus Gigantes/genética
Interações Hospedeiro-Patógeno
Filogenia
Virófagos/genética
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Nm] Nome de substância:
0 (DNA, Viral)
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171019
[Lr] Data última revisão:
171019
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160419
[St] Status:MEDLINE



página 1 de 1
   


Refinar a pesquisa
  Base de dados : MEDLINE Formulário avançado   

    Pesquisar no campo  
1  
2
3
 
           



Search engine: iAH v2.6 powered by WWWISIS

BIREME/OPAS/OMS - Centro Latino-Americano e do Caribe de Informação em Ciências da Saúde