Base de dados : MEDLINE
Pesquisa : B04.450.420 [Categoria DeCS]
Referências encontradas : 2253 [refinar]
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  1 / 2253 MEDLINE  
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[PMID]:27975110
[Au] Autor:Chugh A; Maximos M; Perlman M; Gonzalez-Peralta RP
[Ti] Título:Viral Hepatitis in Children: A Through E.
[So] Source:Pediatr Ann;45(12):e420-e426, 2016 Dec 01.
[Is] ISSN:1938-2359
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Hepatitis is defined as inflammation of the liver. This inflammation can be acute and self-limited, chronic (leading to cirrhosis and an increased risk for hepatocellular carcinoma), or fulminant (requiring lifesaving liver transplantation). Although there are many causes of hepatitis, this article focuses on the main childhood viral hepatidities: types A, B, C, D, and E. This review discusses the main characteristics of each virus, including salient epidemiology, clinical characteristics, diagnosis, treatment, and prevention strategies. [Pediatr Ann. 2016;45(12):e420-e426.].
[Mh] Termos MeSH primário: Hepatite Viral Humana/diagnóstico
Hepatovirus
[Mh] Termos MeSH secundário: Antivirais/uso terapêutico
Criança
Pré-Escolar
Hepatite Viral Humana/epidemiologia
Hepatite Viral Humana/terapia
Seres Humanos
Incidência
Prevalência
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Nm] Nome de substância:
0 (Antiviral Agents)
[Em] Mês de entrada:1703
[Cu] Atualização por classe:170309
[Lr] Data última revisão:
170309
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161216
[St] Status:MEDLINE
[do] DOI:10.3928/19382359-20161114-01


  2 / 2253 MEDLINE  
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[PMID]:26924426
[Au] Autor:Yu JM; Li LL; Zhang CY; Lu S; Ao YY; Gao HC; Xie ZP; Xie GC; Sun XM; Pang LL; Xu JG; Lipkin WI; Duan ZJ
[Ad] Endereço:National Institute for Viral Disease Control and Prevention, China CDC, Beijing, China.
[Ti] Título:A novel hepatovirus identified in wild woodchuck Marmota himalayana.
[So] Source:Sci Rep;6:22361, 2016 Feb 29.
[Is] ISSN:2045-2322
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Hepatitis A virus (HAV) is a hepatotropic picornavirus that causes acute liver disease worldwide. Here, we report on the identification of a novel hepatovirus tentatively named Marmota Himalayana hepatovirus (MHHAV) in wild woodchucks (Marmota Himalayana) in China. The genomic and molecular characterization of MHHAV indicated that it is most closely related genetically to HAV. MHHAV has wide tissue distribution but shows tropism for the liver. The virus is morphologically and structurally similar to HAV. The pattern of its codon usage bias is also consistent with that of HAV. Phylogenetic analysis indicated that MHHAV groups with known HAVs but forms an independent branch, and represents a new species in the genus Hepatovirus within the family Picornaviridae. Antigenic site analysis suggested MHHAV has a new antigenic property to other HAVs. Further evolutionary analysis of MHHAV and primate HAVs led to a most recent common ancestor estimate of 1,000 years ago, while the common ancestor of all HAV-related viruses including phopivirus can be traced back to 1800 years ago. The discovery of MHHAV may provide new insights into the origin and evolution of HAV and a model system with which to explore the pathogenesis of HAV infection.
[Mh] Termos MeSH primário: Hepatovirus/classificação
Marmota/virologia
[Mh] Termos MeSH secundário: Animais
Antígenos Virais
Composição de Bases
Teorema de Bayes
Códon
Epitopos/imunologia
Evolução Molecular
Genoma Viral
Genômica
Genótipo
Hepatovirus/genética
Hepatovirus/imunologia
Hepatovirus/ultraestrutura
Conformação de Ácido Nucleico
Fases de Leitura Aberta
Filogenia
RNA Viral
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (Antigens, Viral); 0 (Codon); 0 (Epitopes); 0 (RNA, Viral)
[Em] Mês de entrada:1612
[Cu] Atualização por classe:161230
[Lr] Data última revisão:
161230
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160301
[St] Status:MEDLINE
[do] DOI:10.1038/srep22361


  3 / 2253 MEDLINE  
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[PMID]:26845898
[Au] Autor:Miyamura T; Kanda T; Yokosuka O
[Ti] Título:[History of the discovery of viral hepatitis].
[So] Source:Nihon Rinsho;73 Suppl 9:7-11, 2015 Dec.
[Is] ISSN:0047-1852
[Cp] País de publicação:Japan
[La] Idioma:jpn
[Mh] Termos MeSH primário: Hepatite Viral Humana
[Mh] Termos MeSH secundário: Hepatite Viral Humana/imunologia
Hepatovirus/genética
Seres Humanos
Vacinas contra Hepatite Viral/imunologia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Viral Hepatitis Vaccines)
[Em] Mês de entrada:1606
[Cu] Atualização por classe:160205
[Lr] Data última revisão:
160205
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160206
[St] Status:MEDLINE


  4 / 2253 MEDLINE  
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[PMID]:26307166
[Au] Autor:Anthony SJ; St Leger JA; Liang E; Hicks AL; Sanchez-Leon MD; Jain K; Lefkowitch JH; Navarrete-Macias I; Knowles N; Goldstein T; Pugliares K; Ip HS; Rowles T; Lipkin WI
[Ad] Endereço:Center for Infection and Immunity, Mailman School of Public Health, Columbia University, New York, New York, USA Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, New York, USA EcoHealth Alliance, New York, New York, USA sja2127@cumc.columbia.edu.
[Ti] Título:Discovery of a Novel Hepatovirus (Phopivirus of Seals) Related to Human Hepatitis A Virus.
[So] Source:MBio;6(4), 2015 Aug 25.
[Is] ISSN:2150-7511
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:UNLABELLED: Describing the viral diversity of wildlife can provide interesting and useful insights into the natural history of established human pathogens. In this study, we describe a previously unknown picornavirus in harbor seals (tentatively named phopivirus) that is related to human hepatitis A virus (HAV). We show that phopivirus shares several genetic and phenotypic characteristics with HAV, including phylogenetic relatedness across the genome, a specific and seemingly quiescent tropism for hepatocytes, structural conservation in a key functional region of the type III internal ribosomal entry site (IRES), and a codon usage bias consistent with that of HAV. IMPORTANCE: Hepatitis A virus (HAV) is an important viral hepatitis in humans because of the substantial number of cases each year in regions with low socioeconomic status. The origin of HAV is unknown, and no nonprimate HAV-like viruses have been described. Here, we describe the discovery of an HAV-like virus in seals. This finding suggests that the diversity and evolutionary history of these viruses might be far greater than previously thought and may provide insight into the origin and pathogenicity of HAV.
[Mh] Termos MeSH primário: Hepatovirus/genética
Hepatovirus/isolamento & purificação
Filogenia
Focas Verdadeiras/virologia
[Mh] Termos MeSH secundário: Animais
Códon
Genoma Viral
Genótipo
Vírus da Hepatite A Humana/genética
Hepatovirus/fisiologia
Sequenciamento de Nucleotídeos em Larga Escala
Seres Humanos
Fígado/virologia
Pulmão/virologia
RNA Viral/genética
Reação em Cadeia da Polimerase em Tempo Real
Baço/virologia
Replicação Viral
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, N.I.H., EXTRAMURAL; RESEARCH SUPPORT, NON-U.S. GOV'T; RESEARCH SUPPORT, U.S. GOV'T, NON-P.H.S.
[Nm] Nome de substância:
0 (Codon); 0 (RNA, Viral)
[Em] Mês de entrada:1606
[Cu] Atualização por classe:161019
[Lr] Data última revisão:
161019
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:150827
[St] Status:MEDLINE


  5 / 2253 MEDLINE  
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[PMID]:25597541
[Au] Autor:Harries M; Monazahian M; Wenzel J; Jilg W; Weber M; Ehlers J; Dreesman J; Mertens E
[Ad] Endereço:Department for Infectious Disease Epidemiology, Governmental Institute of Public Health of Lower Saxony, Hannover, Germany.
[Ti] Título:Foodborne hepatitis A outbreak associated with bakery products in northern Germany, 2012.
[So] Source:Euro Surveill;19(50):20992, 2014 Dec 18.
[Is] ISSN:1560-7917
[Cp] País de publicação:Sweden
[La] Idioma:eng
[Ab] Resumo:In October 2012, a hepatitis A (HA) outbreak with 83 laboratory-confirmed cases occurred in Lower Saxony. We defined primary outbreak cases as people with laboratory-confirmed HA and symptom onset between 8 October and 12 November 2012, residing in or visiting the affected districts. Secondary outbreak cases were persons with symptom onset after 12 November 2012 and close contact with primary cases. We identified 77 primary and six secondary cases. We enrolled 50 primary cases and 52 controls matched for age and sex, and found that 82% of cases and 60% of controls had consumed products from a particular bakery (OR=3.09; 95% CI: 1.15­8.68). Cases were more likely to have eaten sweet pastries (OR=5.74; 95% CI: 1.46­22.42). Viral isolates from five selected cases and three positively tested surfaces in the bakery had identical nucleotide sequences. One additional identical isolate derived from a salesperson of the bakery suffering from a chronic disease that required immunosuppressive treatment. Epidemiological and laboratory findings suggested that the salesperson contaminated products while packing and selling. Future risk assessment should determine whether food handlers with chronic diseases under immunosuppressive treatment could be more at risk of contaminating food and might benefit from HAV immunisation.
[Mh] Termos MeSH primário: Surtos de Doenças
Contaminação de Alimentos/estatística & dados numéricos
Hepatite A/epidemiologia
Hepatovirus/genética
Hepatovirus/isolamento & purificação
[Mh] Termos MeSH secundário: Adolescente
Adulto
Idoso
Sequência de Bases
Estudos de Casos e Controles
Criança
Pré-Escolar
Fezes/virologia
Microbiologia de Alimentos
Alemanha/epidemiologia
Hepatite A/sangue
Hepatite A/transmissão
Hepatite A/virologia
Seres Humanos
Técnicas Imunoenzimáticas
Entrevistas como Assunto
Masculino
Meia-Idade
Análise Multivariada
Vigilância da População
Reação em Cadeia da Polimerase Via Transcriptase Reversa
Medição de Risco
Fatores de Risco
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1505
[Cu] Atualização por classe:150119
[Lr] Data última revisão:
150119
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:150120
[St] Status:MEDLINE


  6 / 2253 MEDLINE  
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[PMID]:25157983
[Au] Autor:Wilson GK; Tennant DA; McKeating JA
[Ad] Endereço:Viral Hepatitis Research Group, Centre for Human Virology, University of Birmingham, Birmingham, UK.
[Ti] Título:Hypoxia inducible factors in liver disease and hepatocellular carcinoma: current understanding and future directions.
[So] Source:J Hepatol;61(6):1397-406, 2014 Dec.
[Is] ISSN:1600-0641
[Cp] País de publicação:Netherlands
[La] Idioma:eng
[Ab] Resumo:Hypoxia inducible transcription factors (HIFs) activate diverse pathways that regulate cellular metabolism, angiogenesis, proliferation, and migration, enabling a cell to respond to a low oxygen or hypoxic environment. HIFs are regulated by oxygen-dependent and independent signals including: mitochondrial dysfunction, reactive oxygen species, endoplasmic reticular stress, and viral infection. HIFs have been reported to play a role in the pathogenesis of liver disease of diverse aetiologies. This review explores the impact of HIFs on hepatocellular biology and inflammatory responses, highlighting the therapeutic potential of targeting HIFs for an array of liver pathologies.
[Mh] Termos MeSH primário: Fatores de Transcrição Hélice-Alça-Hélice Básicos/fisiologia
Carcinoma Hepatocelular/fisiopatologia
Fator 1 Induzível por Hipóxia/fisiologia
Hepatopatias/fisiopatologia
Neoplasias Hepáticas/fisiopatologia
[Mh] Termos MeSH secundário: Animais
Carcinoma Hepatocelular/etiologia
Modelos Animais de Doenças
Hepatovirus/fisiologia
Seres Humanos
Fígado/metabolismo
Fígado/virologia
Hepatopatias/etiologia
Neoplasias Hepáticas/etiologia
Camundongos
Oxigênio/metabolismo
Viroses/fisiopatologia
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T; REVIEW
[Nm] Nome de substância:
0 (Basic Helix-Loop-Helix Transcription Factors); 0 (Hypoxia-Inducible Factor 1); 0 (endothelial PAS domain-containing protein 1); S88TT14065 (Oxygen)
[Em] Mês de entrada:1508
[Cu] Atualização por classe:170922
[Lr] Data última revisão:
170922
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:140827
[St] Status:MEDLINE


  7 / 2253 MEDLINE  
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[PMID]:23297630
[Au] Autor:Marova AA; Oksanich AS; Kaira AN; Meskina ER; Medvedeva EA; Ivanova OE; Lukashev AN; Kyuregian KK; Kalinkina MA; Egorova OV; Zverev VV; Faizuloev EV
[Ti] Título:[Experience of application of multiplex qPCR for differential diagnostics of intestinal viral infections].
[So] Source:Zh Mikrobiol Epidemiol Immunobiol;(6):39-45, 2012 Nov-Dec.
[Is] ISSN:0372-9311
[Cp] País de publicação:Russia (Federation)
[La] Idioma:rus
[Ab] Resumo:AIM: Evaluate the effectiveness of multiplex reverse transcription (RT) and polymerase chain reaction with fluorescence detection in real time mode (qPCR) methods for differential detection of 11 groups of intestine viruses (adenoviruses, enteroviruses, polioviruses, hepatitis A and E viruses, group A and C rotaviruses, orthoreoviruses, noroviruses, sapoviruses and astroviruses) in various biological samples. MATERIALS AND METHODS: Panels of virus isolates and clinical samples characterized by reference methods were used to evaluate sensitivity of detection of various intestine viruses. Nucleic acids were isolated from study samples and multiplex RT and qPCR were carried out. RESULTS: Sensitivity of laboratory reagent kit (LRK) when compared with results obtained from reference methods was 100% for rotavirus A, adenovirus, enterovirus and norovirus, 88.9% for hepatitis E virus and 92.3% for hepatitis A virus, and diagnostic specificity - 99.4%. During analysis of 697 clinical samples from patients with acute intestine infection symptoms nucleic acids of various intestine viruses were isolated in 71.7%. CONCLUSION: Multiplex qRT-PCR was shown as an effective method of etiologic diagnostics of an intestine viral infection. Use of LRK was demonstrated to establish etiology of intestine diseases in 63 - 72% and in children with watery diarrhea - in approximately 90% of cases.
[Mh] Termos MeSH primário: Intestinos/virologia
Viroses/diagnóstico
Viroses/epidemiologia
[Mh] Termos MeSH secundário: Adenoviridae/genética
Adenoviridae/isolamento & purificação
Adulto
Criança
Diagnóstico Diferencial
Enterovirus/genética
Enterovirus/isolamento & purificação
Feminino
Fluorescência
Hepatovirus/genética
Hepatovirus/isolamento & purificação
Seres Humanos
Masculino
Mamastrovirus/genética
Mamastrovirus/isolamento & purificação
Reação em Cadeia da Polimerase Multiplex/métodos
Norovirus/genética
Norovirus/isolamento & purificação
Orthoreovirus/genética
Orthoreovirus/isolamento & purificação
Poliovirus/genética
Poliovirus/isolamento & purificação
Kit de Reagentes para Diagnóstico
Reação em Cadeia da Polimerase em Tempo Real/métodos
Rotavirus/genética
Rotavirus/isolamento & purificação
Federação Russa/epidemiologia
Sapovirus/genética
Sapovirus/isolamento & purificação
Viroses/virologia
[Pt] Tipo de publicação:ENGLISH ABSTRACT; JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Reagent Kits, Diagnostic)
[Em] Mês de entrada:1301
[Cu] Atualização por classe:130109
[Lr] Data última revisão:
130109
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:130110
[St] Status:MEDLINE


  8 / 2253 MEDLINE  
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[PMID]:19941800
[Au] Autor:Urbanus AT; van Houdt R; van de Laar TJ; Coutinho RA
[Ad] Endereço:Cluster Infectious Diseases, Public Health Service, Amsterdam, the Netherlands. aurbanus@ggd.amsterdam.nl
[Ti] Título:Viral hepatitis among men who have sex with men, epidemiology and public health consequences.
[So] Source:Euro Surveill;14(47), 2009 Nov 26.
[Is] ISSN:1560-7917
[Cp] País de publicação:Sweden
[La] Idioma:eng
[Ab] Resumo:Viral hepatitis causes major disease burden worldwide, due to the chronic hepatitis sequelae: cirrhosis and primary liver cancer. Transmission of viral hepatitis is a problem not only in low-income countries, but also in high-income ones where viral hepatitis is a frequently occurring infection among men who have sex with men (MSM). Although the transmission routes of the three main hepatitis viruses, A, B and C, differ, MSM mainly acquire viral hepatitis during sexual contact. Vaccination programmes (only available for hepatitis A and B), raising awareness, and screening can be used to prevent transmission. However, despite the introduction of such methods in many high-income countries, the spread of viral hepatitis among MSM is still ongoing. This paper provides an overview of sexually acquired hepatitis A, B, and C among MSM in high-income countries, using recent insights obtained through molecular epidemiology, with the aim to raise awareness, improve vaccination coverage, and stimulate prevention programs.
[Mh] Termos MeSH primário: Bissexualidade/estatística & dados numéricos
Hepatite Viral Humana/epidemiologia
Homossexualidade Masculina/estatística & dados numéricos
[Mh] Termos MeSH secundário: Comorbidade
Países Desenvolvidos
Hepatite Viral Humana/diagnóstico
Hepatite Viral Humana/prevenção & controle
Hepatite Viral Humana/transmissão
Hepatite Viral Humana/virologia
Hepatovirus/classificação
Hepatovirus/genética
Seres Humanos
Renda
Masculino
Programas de Rastreamento
Países Baixos/epidemiologia
Saúde Pública
Assunção de Riscos
Vacinação
Vacinas contra Hepatite Viral
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Viral Hepatitis Vaccines)
[Em] Mês de entrada:1003
[Cu] Atualização por classe:130501
[Lr] Data última revisão:
130501
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:091128
[St] Status:MEDLINE


  9 / 2253 MEDLINE  
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[PMID]:19930383
[Au] Autor:Frösner G; Steffen R; Herzog C
[Ad] Endereço:Department of Virology, Max von Pettenkofer-Institute, Ludwig-Maximilians-University Munich, Germany.
[Ti] Título:Virosomal hepatitis a vaccine: comparing intradermal and subcutaneous with intramuscular administration.
[So] Source:J Travel Med;16(6):413-9, 2009 Nov-Dec.
[Is] ISSN:1708-8305
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Vaccination against hepatitis A virus (HAV) is unaffordable to many developing countries. Substantial reductions in cost occur when vaccines are administered intradermally at low doses. Aluminum-free HAV vaccines are considered more suitable for intradermal use than traditional vaccines which can cause long-lasting local reactions. Thus, we compared the immunogenicity and safety of an aluminum-free virosomal HAV vaccine (Epaxal) administered by different routes: intradermal (i.d.), subcutaneous (s.c.), and intramuscular (i.m.). METHODS: Two open pilot studies were conducted as sub-studies of a large lot consistency trial. Healthy subjects aged 18 to 45 were enrolled. Study 1 compared two i.d. regimens of a lower dose of Epaxal [0.1 mL (4.8 IU), one or two injection sites] with i.m. administration of the standard dose [0.5 mL (24 IU)]. Study 2 compared the s.c. with the i.m. administration of the standard dose. At month 12, subjects in study 1 received a booster dose of 0.1 mL i.d. or 0.5 mL i.m.; subjects in study 2 received 0.5 mL via the respective route (s.c. or i.m.). Serum was tested for antibodies at baseline, 2 weeks (study 1), and 1 and 6 months after the primary vaccination as well as prior and 1 month after the booster dose. Incidences of solicited and unsolicited adverse events were recorded. RESULTS: Seroprotection rates (anti-HAV geometric mean concentration of > or =20 mIU/mL) after 1 month ranged from 93.2% to 100% in all groups and remained high until month 12 (range 85.2&-90.2%). Complete (100%) seroprotection was achieved by all subjects in all groups after booster vaccination. All routes of administration were well tolerated. Local reactions were more common in subjects vaccinated i.d. and s.c. than i.m. CONCLUSIONS: The aluminum-free virosomal HAV vaccine Epaxal is highly immunogenic and well tolerated when administered either via i.d., s.c., or i.m. Vaccination via the i.d. route may confer significant cost savings over the conventional i.m. route.
[Mh] Termos MeSH primário: Vacinas contra Hepatite A/farmacologia
Hepatite A/prevenção & controle
Hepatovirus/imunologia
[Mh] Termos MeSH secundário: Adolescente
Adulto
Alumínio
Feminino
Alemanha
Anticorpos Anti-Hepatite A/sangue
Vacinas contra Hepatite A/normas
Hepatite Viral Humana
Seres Humanos
Injeções Intradérmicas
Injeções Intramusculares
Injeções Subcutâneas
Masculino
Meia-Idade
Projetos Piloto
Segurança
Suíça
Adulto Jovem
[Pt] Tipo de publicação:CLINICAL TRIAL; COMPARATIVE STUDY; JOURNAL ARTICLE; MULTICENTER STUDY
[Nm] Nome de substância:
0 (Hepatitis A Antibodies); 0 (Hepatitis A Vaccines); CPD4NFA903 (Aluminum)
[Em] Mês de entrada:1004
[Cu] Atualização por classe:131121
[Lr] Data última revisão:
131121
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:091126
[St] Status:MEDLINE
[do] DOI:10.1111/j.1708-8305.2009.00351.x


  10 / 2253 MEDLINE  
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[PMID]:19100778
[Au] Autor:Boog CJ
[Ad] Endereço:The Netherlands Vaccine Institute (NVI), Unit Research and Development, Bilthoven, The Netherlands. claire.boog@nvi-vaccin.nl
[Ti] Título:Principles of vaccination and possible development strategies for rational design.
[So] Source:Immunol Lett;122(2):104-7, 2009 Feb 21.
[Is] ISSN:1879-0542
[Cp] País de publicação:Netherlands
[La] Idioma:eng
[Ab] Resumo:Historically, apart from hygiene, vaccination can be considered as one of the most successful accomplishments of public health in the 20th century. It has lead to some of the greater public health triumphs ever, including the eradication of naturally occurring smallpox and in the control of diseases such as polio. In addition there has been a significant reduction in disease burden imposed by measles, mumps, hepatitis, influenza, diphtheria, haemophilus influenza B and many other infections.
[Mh] Termos MeSH primário: Controle de Doenças Transmissíveis
Vacinação
[Mh] Termos MeSH secundário: Difteria/imunologia
Difteria/prevenção & controle
Hepatite Viral Humana/imunologia
Hepatite Viral Humana/prevenção & controle
Hepatovirus/imunologia
Hepatovirus/patogenicidade
Seres Humanos
Influenza Humana/imunologia
Influenza Humana/prevenção & controle
Sarampo/imunologia
Sarampo/prevenção & controle
Caxumba/imunologia
Caxumba/prevenção & controle
Orthomyxoviridae/imunologia
Orthomyxoviridae/patogenicidade
Poliomielite/imunologia
Poliomielite/prevenção & controle
Poliovirus/imunologia
Poliovirus/patogenicidade
Poxviridae/imunologia
Poxviridae/patogenicidade
Varíola/imunologia
Varíola/prevenção & controle
Resultado do Tratamento
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Em] Mês de entrada:0912
[Cu] Atualização por classe:090317
[Lr] Data última revisão:
090317
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:081223
[St] Status:MEDLINE
[do] DOI:10.1016/j.imlet.2008.11.009



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