Base de dados : MEDLINE
Pesquisa : B04.820.075 [Categoria DeCS]
Referências encontradas : 69 [refinar]
Mostrando: 1 .. 10   no formato [Detalhado]

página 1 de 7 ir para página                  

  1 / 69 MEDLINE  
              next record last record
seleciona
para imprimir
Fotocópia
[PMID]:26478156
[Au] Autor:Noiva R; Guy JS; Hauck R; Shivaprasad HL
[Ti] Título:Runting Stunting Syndrome Associated with Transmissible Viral Proventriculitis in Broiler Chickens.
[So] Source:Avian Dis;59(3):384-7, 2015 Sep.
[Is] ISSN:0005-2086
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:This report describes an outbreak of transmissible viral proventriculitis (TVP) associated with runting stunting syndrome (RSS) in 25- and 28-day-old broiler chickens, in which chicken proventricular necrosis virus (CNPV) was detected. Clinical signs included poor uniformity, very small birds for their age, increased mortality, and culling of smaller birds. Almost all birds necropsied exhibited moderate to severely enlarged proventriculi with diffusely pale serosa and thickened walls. Microscopically the proventriculi had lesions of degeneration and necrosis of the epithelium of the proventricular glands, accompanied by lymphocytic inflammation and glandular hyperplasia, with occasional formation of lymphoid nodules within the glandular parenchyma. Immunohistochemistry staining for CPNV was positive. Positive staining was generally found in the cytoplasm of glandular epithelial cells in the form of finely granular brown pigment. CPNV RNA was detected in the proventriculi by reverse transcriptase-PCR (RT-PCR). Other findings included mild enteritis in a few birds and small bursa of Fabricius. Direct electron microscopy performed on the intestinal samples was negative for viral particles. RT-PCR analysis of bursae was positive for infectious bursal disease virus (IBDV). In conclusion, this report associates TVP with RSS by describing an outbreak in which TVP attributable to CPNV was the most commonly found lesionin chickens with a clinical history compatible with RSS. Therefore, TVP should be considered as a possible differential diagnosis in cases compatible with RSS.
[Mh] Termos MeSH primário: Infecções por Birnaviridae/veterinária
Birnaviridae/isolamento & purificação
Galinhas
Doenças das Aves Domésticas/virologia
Proventrículo/patologia
Gastropatias/veterinária
[Mh] Termos MeSH secundário: Animais
Birnaviridae/classificação
Infecções por Birnaviridae/patologia
Infecções por Birnaviridae/virologia
Proventrículo/virologia
Gastropatias/patologia
Gastropatias/virologia
Ganho de Peso
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1511
[Cu] Atualização por classe:151030
[Lr] Data última revisão:
151030
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:151020
[St] Status:MEDLINE


  2 / 69 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
PubMed Central Texto completo
Texto completo
[PMID]:26336920
[Au] Autor:Mertens J; Casado S; Mata CP; Hernando-Pérez M; de Pablo PJ; Carrascosa JL; Castón JR
[Ad] Endereço:Instituto Madrileño de Estudios Avanzados en Nanociencia (IMDEA Nanociencia) Campus Cantoblanco, 28049 Madrid, Spain.
[Ti] Título:A protein with simultaneous capsid scaffolding and dsRNA-binding activities enhances the birnavirus capsid mechanical stability.
[So] Source:Sci Rep;5:13486, 2015 Sep 04.
[Is] ISSN:2045-2322
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Viral capsids are metastable structures that perform many essential processes; they also act as robust cages during the extracellular phase. Viruses can use multifunctional proteins to optimize resources (e.g., VP3 in avian infectious bursal disease virus, IBDV). The IBDV genome is organized as ribonucleoproteins (RNP) of dsRNA with VP3, which also acts as a scaffold during capsid assembly. We characterized mechanical properties of IBDV populations with different RNP content (ranging from none to four RNP). The IBDV population with the greatest RNP number (and best fitness) showed greatest capsid rigidity. When bound to dsRNA, VP3 reinforces virus stiffness. These contacts involve interactions with capsid structural subunits that differ from the initial interactions during capsid assembly. Our results suggest that RNP dimers are the basic stabilization units of the virion, provide better understanding of multifunctional proteins, and highlight the duality of RNP as capsid-stabilizing and genetic information platforms.
[Mh] Termos MeSH primário: Birnaviridae/química
Birnaviridae/fisiologia
Capsídeo/química
Capsídeo/fisiologia
RNA Viral/química
RNA Viral/fisiologia
[Mh] Termos MeSH secundário: Sítios de Ligação
Módulo de Elasticidade/fisiologia
Ligação Proteica
Ribonucleoproteínas
Estresse Mecânico
Resistência à Tração/fisiologia
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (RNA, Viral); 0 (Ribonucleoproteins)
[Em] Mês de entrada:1607
[Cu] Atualização por classe:150912
[Lr] Data última revisão:
150912
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:150905
[St] Status:MEDLINE
[do] DOI:10.1038/srep13486


  3 / 69 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:25993886
[Au] Autor:McCowan C; Motha J; Crane MS; Moody NJ; Crameri S; Hyatt AD; Bradley T
[Ad] Endereço:Victorian Department of Economic Development, Jobs, Transport and Resources, Agriculture Productivity Division, 5 Ring Road, Bundoora, Victoria 3083, Australia.
[Ti] Título:Isolation of a novel aquatic birnavirus from rainbow trout Oncorhynchus mykiss in Australia.
[So] Source:Dis Aquat Organ;114(2):117-25, 2015 May 21.
[Is] ISSN:0177-5103
[Cp] País de publicação:Germany
[La] Idioma:eng
[Ab] Resumo:In November 2010, a rainbow trout (Oncorhynchus mykiss) hatchery in Victoria reported increased mortality rates in diploid and triploid female fingerlings. Live and moribund fish were submitted for laboratory investigation. All fish showed hyperpigmentation of the cranial half of the body. Histological lesions were seen in all areas of skin examined despite the localised nature of the gross lesions. There was irregular hyperplasia and spongiosis, alternating with areas of thinning and architectural disturbance. Occasionally, particularly in superficial layers of epithelium, cells showed large, eosinophilic inclusions that obscured other cellular detail. A small number of fish had necrosis in dermis, subcutis and superficial muscles. Bacteriological culture of skin and gills was negative for all bacterial pathogens, including Flavibacterium columnare, the agent of columnaris disease. Attempts at virus isolation from the skin of affected fish resulted in the development of a cytopathic effect in RTG-2 cell cultures suggestive of the presence of a virus. Negative contrast electron microscopy of cell culture supernatant demonstrated the presence of viral particles with the typical morphology of birnaviruses. Preliminary molecular characterisation identified an aquabirnavirus that differed from both the Tasmanian aquabirnavirus (TABV) and other aquabirnaviruses exotic to Australia. Previous isolates of aquabirnaviruses in Australia and New Zealand have been from healthy fish in a marine environment. This is the first report of an aquabirnavirus isolated from young salmonids at a freshwater hatchery in Australia. The role of the virus in the mortality event on the farm is uncertain as no further deaths attributable to this virus have occurred in the 4 yr since its initial discovery. The virus has been provisionally named Victorian trout aquabirnavirus (VTAB).
[Mh] Termos MeSH primário: Infecções por Birnaviridae/veterinária
Birnaviridae/classificação
Birnaviridae/isolamento & purificação
Doenças dos Peixes/virologia
Oncorhynchus mykiss/virologia
[Mh] Termos MeSH secundário: Animais
Aquicultura
Austrália/epidemiologia
Birnaviridae/genética
Infecções por Birnaviridae/epidemiologia
Infecções por Birnaviridae/virologia
Feminino
Doenças dos Peixes/epidemiologia
Filogenia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1510
[Cu] Atualização por classe:150521
[Lr] Data última revisão:
150521
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:150522
[St] Status:MEDLINE
[do] DOI:10.3354/dao02858


  4 / 69 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:25107693
[Au] Autor:Kasthuri SR; Wan Q; Whang I; Lim BS; Yeo SY; Choi CY; Lee J
[Ad] Endereço:Department of Marine Life Sciences, School of Marine Biomedical Sciences, Jeju National University, Jeju Self-Governing Province 690-756, Republic of Korea.
[Ti] Título:Functional characterization of the evolutionarily preserved mitochondrial antiviral signaling protein (MAVS) from rock bream, Oplegnathus fasciatus.
[So] Source:Fish Shellfish Immunol;40(2):399-406, 2014 Oct.
[Is] ISSN:1095-9947
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Antimicrobial immune defense is evolutionarily preserved in all organisms. Mammals have developed robust, protein-based antiviral defenses, which are under constant investigation. Studies have provided evidences for the various fish immune factors sharing similarity with those of mammals. In this study, we have identified an ortholog of mitochondrial antiviral signaling protein from rock bream, Oplegnathus fasciatus. RbMAVS cDNA possesses an open reading frame (ORF) of 1758 bp coding for a protein of 586 amino acids with molecular mass of approximately 62 kDa and isoelectric point of 4.6. In silico analysis of RbMAVS protein revealed a caspase recruitment domain (CARD), a proline rich domain and a transmembrane domain. RbMAVS protein also contains a putative TRAF2 binding motif, (319)PVQDT(323). Primary sequence comparison of RbMAVS with other orthologues revealed heterogeneity towards the C-terminus after the CARD region. RbMAVS transcripts were evident in all the examined tissues. RbMAVS expression was induced in vivo after poly I:C challenge in peripheral blood cells, liver, head kidney and spleen tissues. Over-expression of RbMAVS potently inhibited marine birnavirus (MABV) infection in rock bream heart cells and induced various cytokines and signaling molecules in vitro. Thus, RbMAVS is an antiviral protein and potentially involved in the recognition and signaling of antiviral defense mechanism in rock bream.
[Mh] Termos MeSH primário: Proteínas Adaptadoras de Transdução de Sinal/genética
Infecções por Birnaviridae/veterinária
Doenças dos Peixes/imunologia
Proteínas de Peixes/genética
Regulação da Expressão Gênica
Perciformes
[Mh] Termos MeSH secundário: Proteínas Adaptadoras de Transdução de Sinal/metabolismo
Sequência de Aminoácidos
Animais
Birnaviridae/fisiologia
Infecções por Birnaviridae/imunologia
Infecções por Birnaviridae/virologia
Clonagem Molecular
Doenças dos Peixes/virologia
Proteínas de Peixes/química
Proteínas de Peixes/metabolismo
Proteínas Mitocondriais/química
Proteínas Mitocondriais/genética
Proteínas Mitocondriais/metabolismo
Dados de Sequência Molecular
Filogenia
Poli I-C/farmacologia
Reação em Cadeia da Polimerase Via Transcriptase Reversa/veterinária
Alinhamento de Sequência/veterinária
Distribuição Tecidual
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (Adaptor Proteins, Signal Transducing); 0 (Fish Proteins); 0 (Mitochondrial Proteins); O84C90HH2L (Poly I-C)
[Em] Mês de entrada:1505
[Cu] Atualização por classe:171116
[Lr] Data última revisão:
171116
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:140810
[St] Status:MEDLINE


  5 / 69 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:24081931
[Au] Autor:Kim WS; Choi SY; Kim DH; Oh MJ
[Ad] Endereço:1Myung-Joo Oh, Department of Aqualife Medicine, College of Fisheries and Ocean Science, Chonnam National University, Yeosu 550-749, Korea. ohmj@chonnam.ac.kr.
[Ti] Título:A survey of fish viruses isolated from wild marine fishes from the coastal waters of southern Korea.
[So] Source:J Vet Diagn Invest;25(6):750-5, 2013 Nov.
[Is] ISSN:1943-4936
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:A survey was conducted to investigate viral infection in 253 wild marine fishes harvested in the southern coastal area of Korea from 2010 to 2012. The fish that were captured by local anglers were randomly bought and sampled for virus examination. The samples were tested for presence of virus by virus isolation with FHM, FSP, and BF-2 cells and molecular methods (polymerase chain reaction and sequencing). Of the 253 fish sampled, 9 fish were infected with virus. Aquabirnaviruses (ABVs), Viral hemorrhagic septicemia virus (VHSV), and Red seabream iridovirus (RSIV) were detected in 7, 1, and 1 fish, respectively. Molecular phylogenies demonstrated the detected viruses (ABV, VHSV, and RSIV) were more closely related to viruses reported of the same type from Korea and Japan than from other countries, suggesting these viruses may be indigenous to Korean and Japanese coastal waters.
[Mh] Termos MeSH primário: Birnaviridae/isolamento & purificação
Doenças dos Peixes/virologia
Iridovirus/isolamento & purificação
Novirhabdovirus/isolamento & purificação
Filogenia
[Mh] Termos MeSH secundário: Animais
Sequência de Bases
Birnaviridae/genética
Linhagem Celular
Doenças dos Peixes/epidemiologia
Peixes
Iridovirus/genética
Dados de Sequência Molecular
Novirhabdovirus/genética
RNA Viral/química
RNA Viral/genética
República da Coreia/epidemiologia
Reação em Cadeia da Polimerase Via Transcriptase Reversa/veterinária
Alinhamento de Sequência
Análise de Sequência de DNA
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (RNA, Viral)
[Em] Mês de entrada:1406
[Cu] Atualização por classe:131108
[Lr] Data última revisão:
131108
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:131002
[St] Status:MEDLINE
[do] DOI:10.1177/1040638713504755


  6 / 69 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
[PMID]:23397852
[Au] Autor:Marusak RA; West MA; Davis JF; Fletcher OJ; Guy JS
[Ad] Endereço:Department of Population Health and Pathobiology, College of Veterinary Medicine, North Carolina State University, Raleigh, NC 27606, USA.
[Ti] Título:Transmissible viral proventriculitis identified in broiler breeder and layer hens.
[So] Source:Avian Dis;56(4):757-9, 2012 Dec.
[Is] ISSN:0005-2086
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Transmissible viral proventriculitis (TVP) is a recognized cause of production losses in broiler chickens, but previously it has not been reported in broiler breeder and commercial layer hens. In this study, TVP was identified in broiler breeder and commercial layer hens, 9-20 wk of age, based on histopathologic detection of characteristic microscopic lesions. Microscopic lesions in proventriculi of affected hens consisted of glandular epithelial necrosis, ductal epithelial hyperplasia, replacement of glandular epithelium with ductal epithelium, and diffuse interstitial lymphoid infiltration. Additionally, chicken proventricular necrosis virus (CPNV), a virus previously identified as the etiology of TVP in broiler chickens, was detected in proventriculi of TVP-affected hens using a reverse transcriptase-polymerase chain reaction procedure. The findings identify TVP as a potential cause of production losses in broiler breeder and commercial layer hens and provide additional evidence for etiologic involvement in TVP by CPNV.
[Mh] Termos MeSH primário: Birnaviridae/genética
Galinhas
Doenças das Aves Domésticas/diagnóstico
Doenças das Aves Domésticas/virologia
Proventrículo/patologia
Gastropatias/veterinária
[Mh] Termos MeSH secundário: Animais
Birnaviridae/isolamento & purificação
Evolução Fatal
Feminino
Formaldeído/química
Georgia
Inclusão em Parafina/veterinária
Doenças das Aves Domésticas/patologia
Proventrículo/virologia
Reação em Cadeia da Polimerase Via Transcriptase Reversa/veterinária
Análise de Sequência de DNA/veterinária
Gastropatias/diagnóstico
Gastropatias/patologia
Gastropatias/virologia
Proteínas Virais/genética
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (Viral Proteins); 1HG84L3525 (Formaldehyde)
[Em] Mês de entrada:1303
[Cu] Atualização por classe:131121
[Lr] Data última revisão:
131121
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:130213
[St] Status:MEDLINE


  7 / 69 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
PubMed Central Texto completo
Texto completo
[PMID]:23049903
[Au] Autor:Valli A; Busnadiego I; Maliogka V; Ferrero D; Castón JR; Rodríguez JF; García JA
[Ad] Endereço:Centro Nacional de Biotecnología-CSIC, Madrid, Spain.
[Ti] Título:The VP3 factor from viruses of Birnaviridae family suppresses RNA silencing by binding both long and small RNA duplexes.
[So] Source:PLoS One;7(9):e45957, 2012.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:RNA silencing is directly involved in antiviral defense in a wide variety of eukaryotic organisms, including plants, fungi, invertebrates, and presumably vertebrate animals. The study of RNA silencing-mediated antiviral defences in vertebrates is hampered by the overlap with other antiviral mechanisms; thus, heterologous systems are often used to study the interplay between RNA silencing and vertebrate-infecting viruses. In this report we show that the VP3 protein of the avian birnavirus Infectious bursal disease virus (IBDV) displays, in addition to its capacity to bind long double-stranded RNA, the ability to interact with double-stranded small RNA molecules. We also demonstrate that IBDV VP3 prevents the silencing mediated degradation of a reporter mRNA, and that this silencing suppression activity depends on its RNA binding ability. Furthermore, we find that the anti-silencing activity of IBDV VP3 is shared with the homologous proteins expressed by both insect- and fish-infecting birnaviruses. Finally, we show that IBDV VP3 can functionally replace the well-characterized HCPro silencing suppressor of Plum pox virus, a potyvirus that is unable to infect plants in the absence of an active silencing suppressor. Altogether, our results support the idea that VP3 protects the viral genome from host sentinels, including those of the RNA silencing machinery.
[Mh] Termos MeSH primário: Birnaviridae/genética
Interferência de RNA
RNA de Cadeia Dupla/genética
[Mh] Termos MeSH secundário: Agrobacterium/metabolismo
Apoptose
Inativação Gênica
Genes Reporter
Proteínas de Fluorescência Verde/metabolismo
Modelos Genéticos
Orthomyxoviridae/metabolismo
Reação em Cadeia da Polimerase/métodos
Estrutura Terciária de Proteína
RNA Mensageiro/metabolismo
RNA Interferente Pequeno/metabolismo
Tabaco/genética
Proteínas não Estruturais Virais/metabolismo
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (INS1 protein, influenza virus); 0 (RNA, Double-Stranded); 0 (RNA, Messenger); 0 (RNA, Small Interfering); 0 (Viral Nonstructural Proteins); 147336-22-9 (Green Fluorescent Proteins)
[Em] Mês de entrada:1305
[Cu] Atualização por classe:150222
[Lr] Data última revisão:
150222
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:121011
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0045957


  8 / 69 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:23047193
[Au] Autor:van Beurden SJ; Engelsma MY; Roozenburg I; Voorbergen-Laarman MA; van Tulden PW; Kerkhoff S; van Nieuwstadt AP; Davidse A; Haenen OL
[Ad] Endereço:Central Veterinary Institute, Wageningen UR, PO Box 65, 8200 AB Lelystad, The Netherlands.
[Ti] Título:Viral diseases of wild and farmed European eel Anguilla anguilla with particular reference to the Netherlands.
[So] Source:Dis Aquat Organ;101(1):69-86, 2012 Oct 10.
[Is] ISSN:0177-5103
[Cp] País de publicação:Germany
[La] Idioma:eng
[Ab] Resumo:Diseases are an important cause of losses and decreased production rates in freshwater eel farming, and have been suggested to play a contributory role in the worldwide decline in wild freshwater eel stocks. Three commonly detected pathogenic viruses of European eel Anguilla anguilla are the aquabirnavirus eel virus European (EVE), the rhabdovirus eel virus European X (EVEX), and the alloherpesvirus anguillid herpesvirus 1 (AngHV1). In general, all 3 viruses cause a nonspecific haemorrhagic disease with increased mortality rates. This review provides an overview of the current knowledge on the aetiology, prevalence, clinical signs and gross pathology of these 3 viruses. Reported experimental infections showed the temperature dependency and potential pathogenicity of these viruses for eels and other fish species. In addition to the published literature, an overview of the isolation of pathogenic viruses from wild and farmed A. anguilla in the Netherlands during the past 2 decades is given. A total of 249 wild A. anguilla, 39 batches of glass eels intended for farming purposes, and 239 batches of farmed European eels were necropsied and examined virologically. AngHV1 was isolated from wild yellow and silver A. anguilla from the Netherlands from 1998 until the present, while EVEX was only found sporadically, and EVE was never isolated. In farmed A. anguilla AngHV1 was also the most commonly isolated virus, followed by EVE and EVEX.
[Mh] Termos MeSH primário: Anguilla/virologia
Birnaviridae/isolamento & purificação
Doenças dos Peixes/virologia
Herpesviridae/isolamento & purificação
Rhabdoviridae/isolamento & purificação
Viroses/veterinária
[Mh] Termos MeSH secundário: Animais
Aquicultura
Doenças dos Peixes/epidemiologia
Países Baixos/epidemiologia
Viroses/epidemiologia
Viroses/virologia
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T; REVIEW
[Em] Mês de entrada:1301
[Cu] Atualização por classe:121010
[Lr] Data última revisão:
121010
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:121011
[St] Status:MEDLINE
[do] DOI:10.3354/dao02501


  9 / 69 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
PubMed Central Texto completo
Texto completo
[PMID]:22171264
[Au] Autor:Vancini R; Paredes A; Ribeiro M; Blackburn K; Ferreira D; Kononchik JP; Hernandez R; Brown D
[Ad] Endereço:Department of Molecular and Structural Biochemistry, North Carolina State University, Raleigh, North Carolina, USA.
[Ti] Título:Espirito Santo virus: a new birnavirus that replicates in insect cells.
[So] Source:J Virol;86(5):2390-9, 2012 Mar.
[Is] ISSN:1098-5514
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Espirito Santo virus (ESV) is a newly discovered virus recovered as contamination in a sample of a virulent strain of dengue-2 virus (strain 44/2), which was recovered from a patient in the state of Espirito Santo, Brazil, and amplified in insect cells. ESV was found to be dependent upon coinfection with a virulent strain of dengue-2 virus and to replicate in C6/36 insect cells but not in mammalian Vero cells. A sequence of the genome has been produced by de novo assembly and was not found to match to any known viral sequence. An incomplete match to the nucleotide sequence of the RNA-dependent RNA polymerase from Drosophila X virus (DXV), another birnavirus, could be detected. Mass spectrometry analysis of ESV proteins found no matches in the protein data banks. However, peptides recovered by mass spectrometry corresponded to the de novo-assembled sequence by BLAST analysis. The composition and three-dimensional structure of ESV are presented, and its sequence is compared to those of other members of the birnavirus family. Although the virus was found to belong to the family Birnaviridae, biochemical and sequence information for ESV differed from that of DXV, the representative species of the genus Entomobirnavirus. Thus, significant differences underscore the uniqueness of this infectious agent, and its relationship to the coinfecting virus is discussed.
[Mh] Termos MeSH primário: Infecções por Birnaviridae/virologia
Birnaviridae/isolamento & purificação
Birnaviridae/fisiologia
Replicação Viral
[Mh] Termos MeSH secundário: Aedes
Sequência de Aminoácidos
Animais
Birnaviridae/classificação
Birnaviridae/genética
Linhagem Celular
Genoma Viral
Seres Humanos
Dados de Sequência Molecular
Filogenia
Alinhamento de Sequência
Proteínas Virais/química
Proteínas Virais/genética
Cultura de Vírus
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, N.I.H., EXTRAMURAL; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (Viral Proteins)
[Em] Mês de entrada:1204
[Cu] Atualização por classe:170220
[Lr] Data última revisão:
170220
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:111216
[St] Status:MEDLINE
[do] DOI:10.1128/JVI.06614-11


  10 / 69 MEDLINE  
              first record previous record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:21984631
[Au] Autor:Marguerie J; Leon O; Albaric O; Guy JS; Guerin JL
[Ti] Título:Birnavirus-associated proventriculitis in French broiler chickens.
[So] Source:Vet Rec;169(15):394-6, 2011 Oct 08.
[Is] ISSN:2042-7670
[Cp] País de publicação:England
[La] Idioma:eng
[Mh] Termos MeSH primário: Infecções por Birnaviridae/veterinária
Galinhas
Doenças das Aves Domésticas/patologia
Proventrículo/virologia
Gastropatias/veterinária
[Mh] Termos MeSH secundário: Animais
Birnaviridae/isolamento & purificação
Infecções por Birnaviridae/epidemiologia
Infecções por Birnaviridae/mortalidade
Infecções por Birnaviridae/patologia
França/epidemiologia
Doenças das Aves Domésticas/epidemiologia
Doenças das Aves Domésticas/mortalidade
Doenças das Aves Domésticas/virologia
Prevalência
Gastropatias/mortalidade
Gastropatias/patologia
Gastropatias/virologia
[Pt] Tipo de publicação:LETTER
[Em] Mês de entrada:1112
[Cu] Atualização por classe:120510
[Lr] Data última revisão:
120510
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:111011
[St] Status:MEDLINE
[do] DOI:10.1136/vr.d6412



página 1 de 7 ir para página                  
   


Refinar a pesquisa
  Base de dados : MEDLINE Formulário avançado   

    Pesquisar no campo  
1  
2
3
 
           



Search engine: iAH v2.6 powered by WWWISIS

BIREME/OPAS/OMS - Centro Latino-Americano e do Caribe de Informação em Ciências da Saúde