Base de dados : MEDLINE
Pesquisa : B04.820.250.700 [Categoria DeCS]
Referências encontradas : 572 [refinar]
Mostrando: 1 .. 10   no formato [Detalhado]

página 1 de 58 ir para página                         

  1 / 572 MEDLINE  
              next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:28795249
[Au] Autor:Falkenberg SM; Bauermann FV; Ridpath JF
[Ad] Endereço:Ruminant Disease and Immunology Research Unit, National Animal Disease Center, United States Department of Agriculture, Agricultural Research Service, Ames, IA, 50010, USA. Shollie.Falkenberg@ars.usda.gov.
[Ti] Título:Characterization of thymus-associated lymphoid depletion in bovine calves acutely or persistently infected with bovine viral diarrhea virus 1, bovine viral diarrhea virus 2 or HoBi-like pestivirus.
[So] Source:Arch Virol;162(11):3473-3480, 2017 Nov.
[Is] ISSN:1432-8798
[Cp] País de publicação:Austria
[La] Idioma:eng
[Ab] Resumo:Naïve pregnant cattle exposed to pestiviruses between 40-125 days of gestation can give birth to persistently infected (PI) calves. Clinical presentation and survivability, in PI cattle, is highly variable even with the same pestivirus strain whereas the clinical presentation in acute infections is more uniform with severity of symptoms being primarily a function of virulence of the infecting virus. The aim of this study was to compare thymic depletion, as measured by comparing the area of the thymic cortex to the medulla (corticomedullary ratio), in acute and persistent infections of the same pestivirus isolate. The same general trends were observed with each pestivirus isolate. Thymic depletion was observed in both acutely and persistently infected calves. The average thymic depletion observed in acutely infected calves was greater than that in age matched PI calves. PI calves, regardless of infecting virus, revealed a greater variability in amount of depletion compared to acutely infected calves. A trend was observed between survivability and depletion of the thymus, with PI calves surviving less than 5 weeks having lower corticomedullary ratios and greater depletion. This is the first study to compare PI and acutely infected calves with the same isolates as well as to evaluate PI calves based on survivability. Further, this study identified a quantifiable phenotype associated with potential survivability.
[Mh] Termos MeSH primário: Vírus da Diarreia Viral Bovina Tipo 1
Vírus da Diarreia Viral Bovina Tipo 2
Linfócitos/patologia
Infecções por Pestivirus/veterinária
Pestivirus/classificação
Timo/citologia
[Mh] Termos MeSH secundário: Animais
Bovinos
Vírus da Diarreia Viral Bovina Tipo 1/patogenicidade
Vírus da Diarreia Viral Bovina Tipo 2/patogenicidade
Pestivirus/patogenicidade
Infecções por Pestivirus/patologia
Infecções por Pestivirus/virologia
Timo/patologia
Timo/virologia
Virulência
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171027
[Lr] Data última revisão:
171027
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170811
[St] Status:MEDLINE
[do] DOI:10.1007/s00705-017-3523-x


  2 / 572 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:28786787
[Au] Autor:Smith DB; Meyers G; Bukh J; Gould EA; Monath T; Scott Muerhoff A; Pletnev A; Rico-Hesse R; Stapleton JT; Simmonds P; Becher P
[Ad] Endereço:1​Centre for Immunity, Infection and Evolution, University of Edinburgh, Scotland, UK 2​Nuffield Department of Medicine, University of Oxford, UK.
[Ti] Título:Proposed revision to the taxonomy of the genus Pestivirus, family Flaviviridae.
[So] Source:J Gen Virol;98(8):2106-2112, 2017 Aug.
[Is] ISSN:1465-2099
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:We propose the creation of seven new species in the genus Pestivirus (family Flaviviridae) in addition to the four existing species, and naming species in a host-independent manner using the format Pestivirus X. Only the virus species names would change; virus isolates would still be referred to by their original names. The original species would be re-designated as Pestivirus A (original designation Bovine viral diarrhea virus 1), Pestivirus B (Bovine viral diarrhea virus 2), Pestivirus C (Classical swine fever virus) and Pestivirus D (Border disease virus). The seven new species (and example isolates) would be Pestivirus E (pronghorn pestivirus), Pestivirus F (Bungowannah virus), Pestivirus G (giraffe pestivirus), Pestivirus H (Hobi-like pestivirus), Pestivirus I (Aydin-like pestivirus), Pestivirus J (rat pestivirus) and Pestivirus K (atypical porcine pestivirus). A bat-derived virus and pestiviruses identified from sheep and goat (Tunisian sheep pestiviruses), which lack complete coding region sequences, may represent two additional species.
[Mh] Termos MeSH primário: Infecções por Pestivirus/veterinária
Pestivirus/classificação
Pestivirus/isolamento & purificação
[Mh] Termos MeSH secundário: Animais
Bovinos
Cabras
Pestivirus/genética
Pestivirus/fisiologia
Infecções por Pestivirus/virologia
Filogenia
Ratos
Ovinos
Suínos
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1709
[Cu] Atualização por classe:171116
[Lr] Data última revisão:
171116
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170809
[St] Status:MEDLINE
[do] DOI:10.1099/jgv.0.000873


  3 / 572 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:28189886
[Au] Autor:Lanave G; Decaro N; Lucente MS; Guercio A; Cavaliere N; Purpari G; Padalino I; Larocca V; Antoci F; Marino PA; Buonavoglia C; Elia G
[Ad] Endereço:Department of Veterinary Medicine, University of Bari, Valenzano, Bari, Italy.
[Ti] Título:Circulation of multiple subtypes of bovine viral diarrhoea virus type 1 with no evidence for HoBi-like pestivirus in cattle herds of southern Italy.
[So] Source:Infect Genet Evol;50:1-6, 2017 Jun.
[Is] ISSN:1567-7257
[Cp] País de publicação:Netherlands
[La] Idioma:eng
[Ab] Resumo:Pestiviruses of cattle include bovine viral diarrhoea 1 (BVDV-1) and 2 (BVDV-2) plus an emerging group, named HoBi-like pestivirus. In the present paper, the results of an epidemiological survey for pestiviruses circulating in cattle in southern Italy are presented. Molecular assays carried out on a total of 924 bovine samples detected 74 BVDV strains, including 73 BVDV-1 and 1 BVDV-2 viruses. Phylogenetic analysis carried out on partial 5'UTR and N sequences revealed the presence of 6 different subtypes of BVDV-1 and a single BVDV-2c strain. BVDV-1 displayed a high level of genetic heterogeneity, which can have both prophylactic and diagnostic implications. In addition, the detection of BVDV-2c highlights the need for a continuous surveillance for the emergence of new pestivirus strains in cattle farms in southern Italy.
[Mh] Termos MeSH primário: Doença das Mucosas por Vírus da Diarreia Viral Bovina/epidemiologia
Doenças dos Bovinos/epidemiologia
Vírus da Diarreia Viral Bovina Tipo 1/genética
Vírus da Diarreia Viral Bovina Tipo 2/genética
Pestivirus/genética
Filogenia
[Mh] Termos MeSH secundário: Animais
Doença das Mucosas por Vírus da Diarreia Viral Bovina/patologia
Doença das Mucosas por Vírus da Diarreia Viral Bovina/transmissão
Doença das Mucosas por Vírus da Diarreia Viral Bovina/virologia
Bovinos
Doenças dos Bovinos/patologia
Doenças dos Bovinos/transmissão
Doenças dos Bovinos/virologia
Vírus da Diarreia Viral Bovina Tipo 1/classificação
Vírus da Diarreia Viral Bovina Tipo 1/isolamento & purificação
Vírus da Diarreia Viral Bovina Tipo 2/classificação
Vírus da Diarreia Viral Bovina Tipo 2/isolamento & purificação
Monitoramento Epidemiológico
Feminino
Heterogeneidade Genética
Itália/epidemiologia
Pulmão/patologia
Pulmão/virologia
Pestivirus/classificação
Pestivirus/isolamento & purificação
Placenta/patologia
Placenta/virologia
Gravidez
Baço/patologia
Baço/virologia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170921
[Lr] Data última revisão:
170921
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170213
[St] Status:MEDLINE


  4 / 572 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:28151973
[Au] Autor:Dubrau D; Tortorici MA; Rey FA; Tautz N
[Ad] Endereço:Institute of Virology and Cell Biology, University of Luebeck, Luebeck, Germany.
[Ti] Título:A positive-strand RNA virus uses alternative protein-protein interactions within a viral protease/cofactor complex to switch between RNA replication and virion morphogenesis.
[So] Source:PLoS Pathog;13(2):e1006134, 2017 Feb.
[Is] ISSN:1553-7374
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:The viruses of the family Flaviviridae possess a positive-strand RNA genome and express a single polyprotein which is processed into functional proteins. Initially, the nonstructural (NS) proteins, which are not part of the virions, form complexes capable of genome replication. Later on, the NS proteins also play a critical role in virion formation. The molecular basis to understand how the same proteins form different complexes required in both processes is so far unknown. For pestiviruses, uncleaved NS2-3 is essential for virion morphogenesis while NS3 is required for RNA replication but is not functional in viral assembly. Recently, we identified two gain of function mutations, located in the C-terminal region of NS2 and in the serine protease domain of NS3 (NS3 residue 132), which allow NS2 and NS3 to substitute for uncleaved NS2-3 in particle assembly. We report here the crystal structure of pestivirus NS3-4A showing that the NS3 residue 132 maps to a surface patch interacting with the C-terminal region of NS4A (NS4A-kink region) suggesting a critical role of this contact in virion morphogenesis. We show that destabilization of this interaction, either by alanine exchanges at this NS3/4A-kink interface, led to a gain of function of the NS3/4A complex in particle formation. In contrast, RNA replication and thus replicase assembly requires a stable association between NS3 and the NS4A-kink region. Thus, we propose that two variants of NS3/4A complexes exist in pestivirus infected cells each representing a basic building block required for either RNA replication or virion morphogenesis. This could be further corroborated by trans-complementation studies with a replication-defective NS3/4A double mutant that was still functional in viral assembly. Our observations illustrate the presence of alternative overlapping surfaces providing different contacts between the same proteins, allowing the switch from RNA replication to virion formation.
[Mh] Termos MeSH primário: Pestivirus/fisiologia
Proteínas não Estruturais Virais/metabolismo
Vírion/fisiologia
Replicação Viral/fisiologia
[Mh] Termos MeSH secundário: Animais
Western Blotting
Linhagem Celular
Cristalografia por Raios X
Cães
Imunofluorescência
Morfogênese
Mutagênese Sítio-Dirigida
Pestivirus/química
RNA Helicases/química
RNA Helicases/metabolismo
RNA Viral
Serina Endopeptidases/química
Serina Endopeptidases/metabolismo
Proteínas não Estruturais Virais/química
Montagem de Vírus
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (NS3 protein, flavivirus); 0 (NS4A protein, flavivirus); 0 (RNA, Viral); 0 (Viral Nonstructural Proteins); EC 3.4.21.- (Serine Endopeptidases); EC 3.6.4.13 (RNA Helicases)
[Em] Mês de entrada:1708
[Cu] Atualização por classe:170803
[Lr] Data última revisão:
170803
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170203
[St] Status:MEDLINE
[do] DOI:10.1371/journal.ppat.1006134


  5 / 572 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:28082699
[Ti] Título:Congenital tremor associated with atypical porcine pestivirus.
[So] Source:Vet Rec;180(2):42-43, 2017 Jan 14.
[Is] ISSN:2042-7670
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:This article has been prepared by Susanna Williamson and colleagues from the Pig Expert Group at the APHA.
[Mh] Termos MeSH primário: Surtos de Doenças/veterinária
Pestivirus/classificação
Pestivirus/isolamento & purificação
Vigilância de Evento Sentinela/veterinária
Doenças dos Suínos/congênito
Doenças dos Suínos/virologia
Tremor/veterinária
[Mh] Termos MeSH secundário: Animais
Pestivirus/genética
Suínos
Tremor/congênito
Tremor/virologia
Reino Unido/epidemiologia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1706
[Cu] Atualização por classe:170817
[Lr] Data última revisão:
170817
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170114
[St] Status:MEDLINE
[do] DOI:10.1136/vr.j121


  6 / 572 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:28057061
[Au] Autor:Schwarz L; Riedel C; Högler S; Sinn LJ; Voglmayr T; Wöchtl B; Dinhopl N; Rebel-Bauder B; Weissenböck H; Ladinig A; Rümenapf T; Lamp B
[Ad] Endereço:Department for Farm Animals and Veterinary Public Health, University Clinic for Swine, University of Veterinary Medicine Vienna, Veterinaerplatz 1, 1210, Vienna, Austria.
[Ti] Título:Congenital infection with atypical porcine pestivirus (APPV) is associated with disease and viral persistence.
[So] Source:Vet Res;48(1):1, 2017 Jan 06.
[Is] ISSN:1297-9716
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:In 2013, several Austrian piglet-producing farms recorded outbreaks of action-related repetitive myoclonia in newborn piglets ("shaking piglets"). Malnutrition was seen in numerous piglets as a complication of this tremor syndrome. Overall piglet mortality was increased and the number of weaned piglets per sow decreased by more than 10% due to this outbreak. Histological examination of the CNS of affected piglets revealed moderate hypomyelination of the white substance in cerebellum and spinal cord. We detected a recently discovered pestivirus, termed atypical porcine pestivirus (APPV) in all these cases by RT-PCR. A genomic sequence and seven partial sequences were determined and revealed a 90% identity to the US APPV sequences and 92% identity to German sequences. In confirmation with previous reports, APPV genomes were identified in different body fluids and tissues including the CNS of diseased piglets. APPV could be isolated from a "shaking piglet", which was incapable of consuming colostrum, and passaged on different porcine cells at very low titers. To assess the antibody response a blocking ELISA was developed targeting NS3. APPV specific antibodies were identified in sows and in PCR positive piglets affected by congenital tremor (CT). APPV genomes were detected continuously in piglets that gradually recovered from CT, while the antibody titers decreased over a 12-week interval, pointing towards maternally transmitted antibodies. High viral loads were detectable by qRT-PCR in saliva and semen of infected young adults indicating a persistent infection.
[Mh] Termos MeSH primário: Infecções por Pestivirus/veterinária
Pestivirus
Doenças dos Suínos/virologia
[Mh] Termos MeSH secundário: Animais
Animais Recém-Nascidos/virologia
Anticorpos Antivirais/imunologia
Áustria/epidemiologia
Surtos de Doenças/veterinária
Ensaio de Imunoadsorção Enzimática/veterinária
Feminino
Masculino
Pestivirus/genética
Infecções por Pestivirus/congênito
Infecções por Pestivirus/epidemiologia
Infecções por Pestivirus/patologia
Reação em Cadeia da Polimerase Via Transcriptase Reversa/veterinária
Análise de Sequência de DNA/veterinária
Suínos
Doenças dos Suínos/congênito
Doenças dos Suínos/epidemiologia
Doenças dos Suínos/patologia
Carga Viral/veterinária
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Antibodies, Viral)
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170928
[Lr] Data última revisão:
170928
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170107
[St] Status:MEDLINE
[do] DOI:10.1186/s13567-016-0406-1


  7 / 572 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:27907010
[Au] Autor:Blomström AL; Fossum C; Wallgren P; Berg M
[Ad] Endereço:Department of Biomedical Sciences and Veterinary Public Health, Section of Virology, Swedish University of Agricultural Sciences, Uppsala, Sweden.
[Ti] Título:Viral Metagenomic Analysis Displays the Co-Infection Situation in Healthy and PMWS Affected Pigs.
[So] Source:PLoS One;11(12):e0166863, 2016.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:The development of high-throughput sequencing technologies have allowed the possibility to investigate and characterise the entire microbiome of individuals, providing better insight to the complex interaction between different microorganisms. This will help to understand how the microbiome influence the susceptibility of secondary agents and development of disease. We have applied viral metagenomics to investigate the virome of lymph nodes from Swedish pigs suffering from the multifactorial disease postweaning multisystemic wasting syndrome (PMWS) as well as from healthy pigs. The aim is to increase knowledge of potential viruses, apart from porcine circovirus type 2 (PCV2), involved in PMWS development as well as to increase knowledge on the virome of healthy individuals. In healthy individuals, a diverse viral flora was seen with several different viruses present simultaneously. The majority of the identified viruses were small linear and circular DNA viruses, such as different circoviruses, anelloviruses and bocaviruses. In the pigs suffering from PMWS, PCV2 sequences were, as expected, detected to a high extent but other viruses were also identified in the background of PCV2. Apart from DNA viruses also RNA viruses were identified, among them were a porcine pestivirus showing high similarity to a recently (in 2015) discovered atypical porcine pestivirus in the US. Majority of the viruses identified in the background of PCV2 in PMWS pigs could also be identified in the healthy pigs. PCV2 sequences were also identified in the healthy pigs but to a much lower extent than in PMWS affected pigs. Although the method used here is not quantitative the very clear difference in amount of PCV2 sequences in PMWS affected pigs and healthy pigs most likely reflect the very strong replication of PCV2 known to be a hallmark of PMWS. Taken together, these findings illustrate that pigs appear to have a considerable viral flora consisting to a large extent of small single-stranded and circular DNA viruses. Future research on these types of viruses will help to better understand the role that these ubiquitous viruses may have on health and disease of pigs. We also demonstrate for the first time, in Europe, the presence of a novel porcine pestivirus.
[Mh] Termos MeSH primário: Anelloviridae/genética
Bocavirus/genética
Circovirus/genética
Pestivirus/genética
Filogenia
Síndrome Definhante Multissistêmico de Suínos Desmamados/epidemiologia
Doenças dos Suínos/epidemiologia
[Mh] Termos MeSH secundário: Anelloviridae/classificação
Anelloviridae/isolamento & purificação
Animais
Bocavirus/classificação
Bocavirus/isolamento & purificação
Circovirus/classificação
Circovirus/isolamento & purificação
Coinfecção
DNA Viral/genética
Metagenômica
Pestivirus/classificação
Pestivirus/isolamento & purificação
Síndrome Definhante Multissistêmico de Suínos Desmamados/virologia
RNA Viral/genética
Suécia/epidemiologia
Suínos
Doenças dos Suínos/virologia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (DNA, Viral); 0 (RNA, Viral)
[Em] Mês de entrada:1706
[Cu] Atualização por classe:170627
[Lr] Data última revisão:
170627
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161202
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0166863


  8 / 572 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
[PMID]:27782037
[Au] Autor:de Groof A; Deijs M; Guelen L; van Grinsven L; van Os-Galdos L; Vogels W; Derks C; Cruijsen T; Geurts V; Vrijenhoek M; Suijskens J; van Doorn P; van Leengoed L; Schrier C; van der Hoek
[Ad] Endereço:MSD Animal Health/Intervet International bv., Department Discovery & Technology, Wim de Körverstraat 35, P.O. Box 31, 5830AA Boxmeer, The Netherlands. ad.de.groof@merck.com.
[Ti] Título:Atypical Porcine Pestivirus: A Possible Cause of Congenital Tremor Type A-II in Newborn Piglets.
[So] Source:Viruses;8(10), 2016 10 04.
[Is] ISSN:1999-4915
[Cp] País de publicação:Switzerland
[La] Idioma:eng
[Ab] Resumo:Congenital tremor type A-II in piglets has been regarded as a transmissible disease since the 1970s, possibly caused by a very recently-described virus: atypical porcine pestivirus (APPV). Here, we describe several strains of APPV in piglets with clinical signs of congenital tremor (10 of 10 farms tested). Piglets on a farm with no history of congenital tremor were PCR-negative for the virus. To demonstrate a causal relationship between APPV and disease, three gilts were inoculated via intramuscular injection at day 32 of pregnancy. In two of the three litters, vertical transmission of the virus occurred. Clinical signs of congenital tremor were observed in APPV-infected newborns, yet also two asymptomatic carriers were among the offspring. Piglets of one litter were PCR-negative for the virus, and these piglets were all without congenital tremors. Long-term follow up of farm piglets born with congenital tremors showed that the initially high viremia in serum declines at five months of age, but shedding of the virus in feces continues, which explains why the virus remains present at affected farms and causes new outbreaks. We conclude that trans-placental transmission of APPV and subsequent infection of the fetuses is a very likely cause of congenital tremor type A-II in piglets.
[Mh] Termos MeSH primário: Infecções por Pestivirus/veterinária
Pestivirus/patogenicidade
Doenças dos Suínos/congênito
Tremor/veterinária
[Mh] Termos MeSH secundário: Animais
Animais Recém-Nascidos
Fezes/virologia
Pestivirus/isolamento & purificação
Infecções por Pestivirus/congênito
Suínos
Fatores de Tempo
Tremor/congênito
Viremia/veterinária
Viremia/virologia
Eliminação de Partículas Virais
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170913
[Lr] Data última revisão:
170913
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161027
[St] Status:MEDLINE


  9 / 572 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
[PMID]:27741408
[Au] Autor:Hartlage AS; Cullen JM; Kapoor A
[Ad] Endereço:Center for Vaccines and Immunity, The Research Institute at Nationwide Children's Hospital, Columbus, Ohio 43205; email: amit.kapoor@nationwidechildrens.org.
[Ti] Título:The Strange, Expanding World of Animal Hepaciviruses.
[So] Source:Annu Rev Virol;3(1):53-75, 2016 Sep 29.
[Is] ISSN:2327-0578
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Hepaciviruses and pegiviruses constitute two closely related sister genera of the family Flaviviridae. In the past five years, the known phylogenetic diversity of the hepacivirus genera has absolutely exploded. What was once an isolated infection in humans (and possibly other primates) has now expanded to include horses, rodents, bats, colobus monkeys, cows, and, most recently, catsharks, shedding new light on the genetic diversity and host range of hepaciviruses. Interestingly, despite the identification of these many animal and primate hepaciviruses, the equine hepaciviruses remain the closest genetic relatives of the human hepaciviruses, providing an intriguing clue to the zoonotic source of hepatitis C virus. This review summarizes the significance of these studies and discusses current thinking about the origin and evolution of the animal hepaciviruses as well as their potential usage as surrogate models for the study of hepatitis C virus.
[Mh] Termos MeSH primário: Flavivirus/genética
Vírus GB A/classificação
Vírus GB C/classificação
Genoma Viral/genética
Hepacivirus/genética
Hepatite C/veterinária
Pestivirus/classificação
[Mh] Termos MeSH secundário: Animais
Bovinos/virologia
Quirópteros/virologia
Colobus/virologia
Flavivirus/classificação
Vírus GB A/genética
Vírus GB C/genética
Variação Genética/genética
Hepacivirus/classificação
Hepatite C/virologia
Cavalos/virologia
Especificidade de Hospedeiro
Seres Humanos
Pestivirus/genética
Tubarões/virologia
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Em] Mês de entrada:1711
[Cu] Atualização por classe:171109
[Lr] Data última revisão:
171109
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161015
[St] Status:MEDLINE


  10 / 572 MEDLINE  
              first record previous record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:27478131
[Au] Autor:Shi H; Kan Y; Yao L; Leng C; Tang Q; Ji J; Sun S
[Ad] Endereço:Henan Provincial Engineering Laboratory of Insects Bio-reactor, China-UK-NYNU-RRes Joint Libratory of Insect Biology, Nanyang Normal University, Nanyang, China.
[Ti] Título:Identification of Natural Infections in Sheep/Goats with HoBi-like Pestiviruses in China.
[So] Source:Transbound Emerg Dis;63(5):480-4, 2016 Oct.
[Is] ISSN:1865-1682
[Cp] País de publicação:Germany
[La] Idioma:eng
[Ab] Resumo:The natural infections of HoBi-like pestiviruses in cattle have been reported in South America, Europe and Asia. In China, although the detections of HoBi-like pestivirus have been reported, the epidemiological investigation was limited. From January 2014 to October 2015, several flocks of sheep/goats in Henan province in central China suffered respiratory diseases which were recovered slowly after antibiotics treatment. To test whether it is the HoBi-like pestivirus caused this symptom, 49 serum samples and 22 nasal swabs were then collected for analysis by serology and RT-PCR. Serological result revealed that prevalence of pestivirus in small ruminants was 12.2% (6/49) in central China. Sequence analysis of partial 5'-UTR nucleotides of pestivirus-positive samples suggested that HoBi-like pestivirus might have circulated in sheep/goats of China for a period and have evolved into new genotype clusters. It is apparent that the study provides the molecular evidence of natural infections in goat/sheep species with HoBi-like pestiviruses in China.
[Mh] Termos MeSH primário: Infecções por Pestivirus/diagnóstico
Infecções por Pestivirus/veterinária
Pestivirus/genética
[Mh] Termos MeSH secundário: Animais
China/epidemiologia
Genótipo
Cabras/virologia
Infecções por Pestivirus/epidemiologia
Reação em Cadeia da Polimerase
Ovinos/virologia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1701
[Cu] Atualização por classe:170119
[Lr] Data última revisão:
170119
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160802
[St] Status:MEDLINE
[do] DOI:10.1111/tbed.12551



página 1 de 58 ir para página                         
   


Refinar a pesquisa
  Base de dados : MEDLINE Formulário avançado   

    Pesquisar no campo  
1  
2
3
 
           



Search engine: iAH v2.6 powered by WWWISIS

BIREME/OPAS/OMS - Centro Latino-Americano e do Caribe de Informação em Ciências da Saúde