[PMID]: | 26822138 |
[Au] Autor: | Wang F; Lin J; Chang J; Cao Y; Qin S; Wu J; Yu L |
[Ad] Endereço: | Division of Livestock Infectious Diseases, State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin, People's Republic of China. wfangemail@aliyun.com. |
[Ti] Título: | Isolation, complete genome sequencing, and phylogenetic analysis of the first Chuzan virus in China. |
[So] Source: | Virus Genes;52(1):138-41, 2016 Feb. |
[Is] ISSN: | 1572-994X |
[Cp] País de publicação: | United States |
[La] Idioma: | eng |
[Ab] Resumo: | A Chuzan virus (CHUV), defined as GX871 here, was isolated from blood from a sentinel cattle firstly in China, and its full-length genome was sequenced in this study. The GX871 genome included 10 segments and 18914 bp, one base fewer than the CHUV prototype strain K-47 due to a one-base deletion in the 5' non-coding region of segment 8. A frameshift mutation was detected in a short coding region (1010-1026 nt) corresponding to the VP1 protein; this frameshift resulted in a five-amino acid mutation from 336CVLSY340 to 336YGAKL340. In addition, there were a one-base deletion at 1713 nt and a one-base insertion at 1682 nt in the 3' non-coding region of segment 5. Based on phylogenetic analysis of the deduced VP2 amino acid sequences, Palyam serogroup viruses were classified into three groups. The Chinese CHUV isolate GX871 was categorized into the same group as CHUV prototype strain K-47. The phylogenetic tree was divided into three clusters according to the geographical distribution of the partial nucleotide sequences of VP7, and this arrangement might define the geographical gene pool of CHUV. |
[Mh] Termos MeSH primário: |
Bovinos/virologia Vírus Palyam/genética Vírus Palyam/isolamento & purificação
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[Mh] Termos MeSH secundário: |
Animais China Genoma Viral Vírus Palyam/classificação Filogenia
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[Pt] Tipo de publicação: | JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T |
[Em] Mês de entrada: | 1610 |
[Cu] Atualização por classe: | 171102 |
[Lr] Data última revisão:
| 171102 |
[Sb] Subgrupo de revista: | IM |
[Da] Data de entrada para processamento: | 160130 |
[St] Status: | MEDLINE |
[do] DOI: | 10.1007/s11262-015-1282-x |
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