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[PMID]:29431330
[Au] Autor:Deynego VN; Elizarov VB; Kaptsov VA
[Ti] Título:[Hygienic and environmental problems of energy-saving illumination in urbanization of Crimea].
[So] Source:Gig Sanit;95(10):909-13, 2016.
[Is] ISSN:0016-9900
[Cp] País de publicação:Russia (Federation)
[La] Idioma:rus
[Ab] Resumo:The article considers the problems offloodlights pollution in the territory of Crimea due to the work of illumination led equipment of the key elements of the international transport artery "China-Europe". There was performed a qualitative assessment of characteristics of led floodlights pollution on the example of the sea surface of the transport crossing through the Kerch Strait. Ichthyologists and oceanographers were shown to estimate the amount of phytoplankton biomass based on sunlight illumination. The excess dose of blue light in the spectrum of led lighting was established to have an impact on phytoplankton greater than solar and lunar light, creating preconditions for the increase of biological mass of phytoplankton and consequently to the formation of the "stern stock". Arising from additional phytoplankton biomass can significantly influence on the schedule offish migration in waters of the Kerch Strait, the biomass of mosquitoes and midges, which are prey for amphibians and birds. The decline of the both light pollution and its negative impact on fauna andflora requires the development of semiconductor sources of white light with a biologically adequate spectrum in the framework of the "Lighting of the lighting equipment of Crimea".
[Mh] Termos MeSH primário: Organismos Aquáticos
Poluição Ambiental
Luz/efeitos adversos
Iluminação
Processos Fototróficos/efeitos da radiação
Urbanização
[Mh] Termos MeSH secundário: Organismos Aquáticos/fisiologia
Organismos Aquáticos/efeitos da radiação
Poluição Ambiental/efeitos adversos
Poluição Ambiental/análise
Poluição Ambiental/prevenção & controle
Seres Humanos
Iluminação/efeitos adversos
Iluminação/métodos
Iluminação/normas
Fotometria/métodos
Fotometria/normas
Fitoplâncton/fisiologia
Fitoplâncton/efeitos da radiação
Saúde Pública/métodos
Saúde Pública/normas
Federação Russa/epidemiologia
Mudança Social
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1803
[Cu] Atualização por classe:180309
[Lr] Data última revisão:
180309
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180213
[St] Status:MEDLINE


  2 / 4049 MEDLINE  
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[PMID]:28844981
[Au] Autor:Gogineni V; Hamann MT
[Ad] Endereço:Department of BioMolecular Sciences, Division of Medicinal Chemistry, School of Pharmacy, The University of Mississippi, University, MS, United States. Electronic address: vgoginen@go.olemiss.edu.
[Ti] Título:Marine natural product peptides with therapeutic potential: Chemistry, biosynthesis, and pharmacology.
[So] Source:Biochim Biophys Acta;1862(1):81-196, 2018 01.
[Is] ISSN:0006-3002
[Cp] País de publicação:Netherlands
[La] Idioma:eng
[Ab] Resumo:The oceans are a uniquely rich source of bioactive metabolites, of which sponges have been shown to be among the most prolific producers of diverse bioactive secondary metabolites with valuable therapeutic potential. Much attention has been focused on marine bioactive peptides due to their novel chemistry and diverse biological properties. As summarized in this review, marine peptides are known to exhibit various biological activities such as antiviral, anti-proliferative, antioxidant, anti-coagulant, anti-hypertensive, anti-cancer, antidiabetic, antiobesity, and calcium-binding activities. This review focuses on the chemistry and biology of peptides isolated from sponges, bacteria, cyanobacteria, fungi, ascidians, and other marine sources. The role of marine invertebrate microbiomes in natural products biosynthesis is discussed in this review along with the biosynthesis of modified peptides from different marine sources. The status of peptides in various phases of clinical trials is presented, as well as the development of modified peptides including optimization of PK and bioavailability.
[Mh] Termos MeSH primário: Anti-Hipertensivos
Antineoplásicos
Antivirais
Organismos Aquáticos/química
Hipoglicemiantes
Biossíntese Peptídica
Peptídeos
[Mh] Termos MeSH secundário: Animais
Anti-Hipertensivos/química
Anti-Hipertensivos/uso terapêutico
Antineoplásicos/química
Antineoplásicos/uso terapêutico
Antivirais/química
Antivirais/uso terapêutico
Organismos Aquáticos/metabolismo
Seres Humanos
Hipoglicemiantes/química
Hipoglicemiantes/uso terapêutico
Peptídeos/química
Peptídeos/uso terapêutico
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, N.I.H., EXTRAMURAL; RESEARCH SUPPORT, NON-U.S. GOV'T; REVIEW
[Nm] Nome de substância:
0 (Antihypertensive Agents); 0 (Antineoplastic Agents); 0 (Antiviral Agents); 0 (Hypoglycemic Agents); 0 (Peptides)
[Em] Mês de entrada:1803
[Cu] Atualização por classe:180309
[Lr] Data última revisão:
180309
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170829
[St] Status:MEDLINE


  3 / 4049 MEDLINE  
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[PMID]:28968938
[Au] Autor:Rotini A; Gallo A; Parlapiano I; Berducci MT; Boni R; Tosti E; Prato E; Maggi C; Cicero AM; Migliore L; Manfra L
[Ad] Endereço:Department of Biology, University Tor Vergata, Rome, Italy; Institute for Environmental Protection and Research (ISPRA), Rome, Italy.
[Ti] Título:Insights into the CuO nanoparticle ecotoxicity with suitable marine model species.
[So] Source:Ecotoxicol Environ Saf;147:852-860, 2018 Jan.
[Is] ISSN:1090-2414
[Cp] País de publicação:Netherlands
[La] Idioma:eng
[Ab] Resumo:Metal oxide nanoparticles, among them copper oxide nanoparticles (CuO NPs), are widely used in different applications (e.g. batteries, gas sensors, superconductors, plastics and metallic coatings), increasing their potential release in the environment. In aquatic matrix, the behavior of CuO NPs may strongly change, depending on their surface charge and some physical-chemical characteristics of the medium (e.g. ionic strength, salinity, pH and natural organic matter content). Ecotoxicity of CuO NPs to aquatic organisms was mainly studied on freshwater species, few tests being performed on marine biota. The aim of this study was to assess the toxicity of CuO NPs on suitable indicator species, belonging to the ecologically relevant level of consumers. The selected bioassays use reference protocols to identify Effect/Lethal Concentrations (E(L)C), by assessing lethal and sub-lethal endpoints. Mortality tests were performed on rotifer (Brachionus plicatilis), shrimp (Artemia franciscana) and copepod (Tigriopus fulvus). While moult release failure and fertilization rate were studied, as sub-lethal endpoints, on T. fulvus and sea urchin (Paracentrotus lividus), respectively. The size distribution and sedimentation rates of CuO NPs, together with the copper dissolution, were also analyzed in the exposure media. The CuO NP ecotoxicity assessment showed a concentration-dependent response for all species, indicating similar mortality for B. plicatilis (48hLC = 16.94 ± 2.68mg/l) and T. fulvus (96hLC = 12.35 ± 0.48mg/l), followed by A. franciscana (48hLC = 64.55 ± 3.54mg/l). Comparable EC values were also obtained for the sub-lethal endpoints in P. lividus (EC = 2.28 ± 0.06mg/l) and T. fulvus (EC = 2.38 ± 0.20mg/l). Copper salts showed higher toxicity than CuO NPs for all species, with common sensitivity trend as follows: P. lividus ≥ T. fulvus (sublethal endpoint) ≥ B. plicatilis >T. fulvus (lethal endpoint) >A. franciscana. CuO NP micrometric aggregates and high sedimentation rates were observed in the exposure media, with different particle size distributions depending on the medium. The copper dissolution was about 0.16% of the initial concentration, comparable to literature values. The integrated ecotoxicological-physicochemical approach was used to better describe CuO NP toxicity and behavior. In particular, the successful application of ecotoxicological reference protocols allowed to produce reliable L(E)C data useful to identify thresholds and assess potential environmental hazard due to NPs.
[Mh] Termos MeSH primário: Organismos Aquáticos/efeitos dos fármacos
Cobre/toxicidade
Nanopartículas Metálicas/toxicidade
Poluentes Químicos da Água/toxicidade
[Mh] Termos MeSH secundário: Animais
Ecotoxicologia
Água Doce
Modelos Animais
Tamanho da Partícula
Salinidade
Especificidade da Espécie
Propriedades de Superfície
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Water Pollutants, Chemical); 789U1901C5 (Copper); V1XJQ704R4 (cupric oxide)
[Em] Mês de entrada:1803
[Cu] Atualização por classe:180308
[Lr] Data última revisão:
180308
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171004
[St] Status:MEDLINE


  4 / 4049 MEDLINE  
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[PMID]:28595450
[Au] Autor:Jiang W; Zhou W; Othman R; Uchida H; Watanabe R; Suzuki T; Sakamoto B; Nagai H
[Ad] Endereço:a Department of Ocean Sciences , Tokyo University of Marine Science and Technology , Tokyo , Japan.
[Ti] Título:A new malyngamide from the marine cyanobacterium Moorea producens.
[So] Source:Nat Prod Res;32(1):97-104, 2018 Jan.
[Is] ISSN:1478-6427
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:A new malyngamide (1) was isolated along with seven known compounds (2-8) from the marine cyanobacterium Moorea producens collected in Hawaii. Compound 1 represented the first reported malyngamide with a hydroxy moiety at C-7 of the characteristic fatty acid portion of the compound. Compound 1 showed cytotoxicity against L1210 cell line at an IC value of 2.9 mM and lethal toxicity against the shrimp Palaemon paucidens at a LD value of 33.3 mg/kg. The bioactivity of compound 1 was approximately 10-100 times weaker than those of isomalyngamides A and B (3, 4). These results indicated that the methoxy group at C-7 of the fatty acid section confers a degree of bioactivity in malyngamides.
[Mh] Termos MeSH primário: Cianobactérias/química
Lipopeptídeos/química
Lipopeptídeos/farmacologia
[Mh] Termos MeSH secundário: Amidas/química
Amidas/farmacologia
Animais
Organismos Aquáticos/química
Linhagem Celular Tumoral
Leucemia L1210
Espectroscopia de Ressonância Magnética
Camundongos
Estrutura Molecular
Palaemonidae/efeitos dos fármacos
Pirróis/química
Pirróis/farmacologia
Relação Estrutura-Atividade
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Amides); 0 (Lipopeptides); 0 (Pyrroles); 0 (isomalyngamide A); 0 (isomalyngamide B)
[Em] Mês de entrada:1803
[Cu] Atualização por classe:180301
[Lr] Data última revisão:
180301
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170610
[St] Status:MEDLINE
[do] DOI:10.1080/14786419.2017.1338282


  5 / 4049 MEDLINE  
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[PMID]:28592143
[Au] Autor:Pang X; Lin X; Tian Y; Liang R; Wang J; Yang B; Zhou X; Kaliyaperumal K; Luo X; Tu Z; Liu Y
[Ad] Endereço:a CAS Key Laboratory of Tropical Marine Bio-resources and Ecology/Guangdong Key Laboratory of Marine Materia Medica/RNAM Center for Marine Microbiology , South China Sea Institute of Oceanology, Chinese Academy of Sciences , Guangzhou , China.
[Ti] Título:Three new polyketides from the marine sponge-derived fungus Trichoderma sp. SCSIO41004.
[So] Source:Nat Prod Res;32(1):105-111, 2018 Jan.
[Is] ISSN:1478-6427
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Three new polyketides named trichbenzoisochromen A (1), 5,7-dihydroxy-3-methyl -2-(2-oxopropyl)naphthalene-1,4-dione (2) and 7-acetyl-1,3,6-trihydroxyanthracene-9,10- dione (3) together with six known compounds (4-9) were isolated from a sponge-derived fungus Trichoderma sp. SCSIO41004. The structures of three new polyketides (1-3) were determined by the extensive spectroscopic analysis, including 1D, 2D NMR and HRESIMS data. The absolute configuration of compound 1 was confirmed by the specific optical rotation value and CD spectra analyses. Compound 4 exhibited significant inhibitory activity against EV71 with the IC value of 25.7 µM.
[Mh] Termos MeSH primário: Antracenos/química
Antivirais/química
Antivirais/farmacologia
Naftalenos/química
Policetídeos/química
Trichoderma/química
[Mh] Termos MeSH secundário: Animais
Antracenos/farmacologia
Organismos Aquáticos/química
Dicroísmo Circular
Enterovirus Humano A/efeitos dos fármacos
Fermentação
Seres Humanos
Vírus da Influenza A Subtipo H3N2/efeitos dos fármacos
Células K562
Células MCF-7
Espectroscopia de Ressonância Magnética/métodos
Estrutura Molecular
Naftalenos/farmacologia
Policetídeos/farmacologia
Poríferos/microbiologia
Espectrometria de Massas por Ionização por Electrospray
Trichoderma/metabolismo
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Anthracenes); 0 (Antiviral Agents); 0 (Naphthalenes); 0 (Polyketides)
[Em] Mês de entrada:1803
[Cu] Atualização por classe:180301
[Lr] Data última revisão:
180301
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170609
[St] Status:MEDLINE
[do] DOI:10.1080/14786419.2017.1338286


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[PMID]:28468259
[Au] Autor:Han Z; Li YX; Liu LL; Lu L; Guo XR; Zhang XX; Zhang XY; Qi SH; Xu Y; Qian PY
[Ad] Endereço:Institute of Deep-sea Science and Engineering, Chinese Academy of Sciences, 28 Luhuitou Road, Sanya 572000, China. zhuanghan@idsse.ac.cn.
[Ti] Título:Thielavins W-Z7, New Antifouling Thielavins from the Marine-Derived Fungus Thielavia sp. UST030930-004.
[So] Source:Mar Drugs;15(5), 2017 Apr 29.
[Is] ISSN:1660-3397
[Cp] País de publicação:Switzerland
[La] Idioma:eng
[Ab] Resumo:Eleven new depsides-thielavins W-Z ( - ) and thielavins Z1-Z7 ( - )-and also four known thielavins-A, H, J, and K ( - )-were isolated from the ethyl acetate extract of a marine-derived fungal strain sp UST030930-004. All of these compounds were evaluated for antifouling activity against cyprids of the barnacle (= ) . The results showed that compounds 1-3 and 6-13 were active, with EC values ranging from 2.95 ± 0.59 to 69.19 ± 9.51 µM, respectively. The inhibitive effect of compounds - and was reversible. This is the first description of the antifouling activity of thielavins against barnacle cyprids.
[Mh] Termos MeSH primário: Organismos Aquáticos/química
Incrustação Biológica/prevenção & controle
Depsídeos/química
Depsídeos/farmacologia
Fungos/química
Hidroxibenzoatos/química
Hidroxibenzoatos/farmacologia
Sordariales/química
[Mh] Termos MeSH secundário: Animais
Thoracica/efeitos dos fármacos
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Depsides); 0 (Hydroxybenzoates)
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180228
[Lr] Data última revisão:
180228
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170505
[St] Status:MEDLINE


  7 / 4049 MEDLINE  
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[PMID]:29202309
[Au] Autor:Grimonprez A; Molza A; Laurent MCZ; Mansot JL; Gros O
[Ad] Endereço:Sorbonne Universités, UPMC Univ Paris 06, Univ Antilles Guyane, Univ Nice Sophia Antipolis, CNRS, Evolution Paris Seine-Institut de Biologie Paris Seine (EPS-IBPS), 75005 Paris, France. Electronic address: Adrien.Grimonprez@etu.univ-antilles.fr.
[Ti] Título:Thioautotrophic ectosymbiosis in Pseudovorticella sp., a peritrich ciliate species colonizing wood falls in marine mangrove.
[So] Source:Eur J Protistol;62:43-55, 2018 Feb.
[Is] ISSN:1618-0429
[Cp] País de publicação:Germany
[La] Idioma:eng
[Ab] Resumo:Ciliates represent a diversified group of protists known to establish symbioses with prokaryotic micro-organisms. They are mainly phagotrophs and symbiotic relationships with bacteria can give them an important advantage in chemosynthetic environments. The aim of this study is to describe the thiotrophic association that occurs between the peritrich ciliate Pseudovorticella sp. and potential sulfur-oxidizing bacteria. Investigations at microscopic scale (LM, SEM, TEM) showed ectosymbiotic bacteria covering the surface of the body of Pseudovorticella sp. According to 16S rDNA phylogenetic analysis, these ectosymbiotic bacteria belong to γ-proteobacteria and are phylogenetically close to the symbiont of the recently described Zoothamnium ignavum, which inhabits shallow-water wood falls. FISH experiments, using symbiont specific probes, clearly indicate that these ectosymbiotic bacteria are also ingested into food vacuoles. Electron lucent granules observed in TEM in the cytoplasm of the ectosymbiotic bacteria have been identified as sulfur granules by Raman microspectrometry analyses. Raman microspectrometry analyses confirmed the thiotrophic nature of this relationship already suggested by the results obtained by TEM and phylogeny. A complete sulfur map was then performed to investigate the sulfur distribution in the zooid. Results show that the relationship between this protist and its bacterial partner is a thiotrophic ectosymbiosis.
[Mh] Termos MeSH primário: Organismos Aquáticos/fisiologia
Fenômenos Fisiológicos Bacterianos
Oligoimenóforos/microbiologia
Simbiose
[Mh] Termos MeSH secundário: Organismos Aquáticos/genética
Bactérias/genética
Bactérias/ultraestrutura
DNA Ribossômico/genética
Oligoimenóforos/genética
Oligoimenóforos/fisiologia
Oligoimenóforos/ultraestrutura
Filogenia
RNA Ribossômico 16S/genética
Madeira/microbiologia
Madeira/parasitologia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (DNA, Ribosomal); 0 (RNA, Ribosomal, 16S)
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180223
[Lr] Data última revisão:
180223
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171205
[St] Status:MEDLINE


  8 / 4049 MEDLINE  
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[PMID]:29251479
[Au] Autor:Thiyagarajan S; Bavya M; Jamal A
[Ti] Título:Isolation of marine fungi Aspergillus sp. and its in vitro antifouling activity against marine bacteria.
[So] Source:J Environ Biol;37(5):895-903, 2016 09.
[Is] ISSN:0254-8704
[Cp] País de publicação:India
[La] Idioma:eng
[Ab] Resumo:Biofouling is considered as a main issue of concern in aquatic environment causing severe economic loss and pollution. The aim of the present study was to isolate marine fungus antagonistic to biofouling bacteria and to define antifouling compounds present in it. Using standard plate method five predominant biofouling bacteria viz., Methylococcus sp., Flavobacterium sp., Marinococcus sp., Serratia sp. and Pseudomonas sp. were isolated from marine solid substances on Zobell's agar. Tolerance range of these bacteria to NaCl was 2-10%. Isolation of fungi from mangrove and estuarine sediments and their screening identified Aspergillus sp. EF4 as a potential isolate. This isolate caused inhibition of all the five test bacterial cultures measuring zone diameters respectively of 11, 16, 12, 13 and 11mm.? Subsequent to submerged fermentation using shaking flask method this fungus produced bioactive compounds within 5 days. The culture parameters optimized were raffinose as carbon source, yeast extract as lone nitrogen source, pH up to 9.0 and temperature up to 40?C. Antifouling compounds of culture filtrate were separated and detected by a three-step procedure involving thin layer chromatography, bioautography and preparative TLC. The in vitro assay involving glass slide-wooden stick-biofilm method revealed that these compounds could cause inhibition and destruction of bacteria to an extent of 2.16 x 104 CFU ml-1 and 2.46 x 104 CFU ml-1 respectively while growth of bacteria in control beaker was enumerated to be 4.41 x 104 CFU ml-1. High performance liquid chromatography of culture filtrate indicated probable principal antifouling compound as Fumonisin B2. Isolation of antagonistic marine fungus from Indian coast and detection of its antifouling compound would help in planning effective strategies for controlling biofouling in marine environment.
[Mh] Termos MeSH primário: Antibiose
Aspergillus/fisiologia
Bactérias/classificação
Incrustação Biológica
[Mh] Termos MeSH secundário: Organismos Aquáticos
Fenômenos Fisiológicos Bacterianos
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180222
[Lr] Data última revisão:
180222
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171219
[St] Status:MEDLINE


  9 / 4049 MEDLINE  
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[PMID]:29273953
[Au] Autor:Coutinho MCL; Teixeira VL; Santos CSG
[Ad] Endereço:Department of Marine Biology, Institute of Biology, Federal Fluminense University, Outeiro São João Batista, s/no, P.O. Box 100.644, Niterói, RJ, 24020-150, Brazil. marinacoutinho88@gmail.com.
[Ti] Título:A Review of "Polychaeta" Chemicals and their Possible Ecological Role.
[So] Source:J Chem Ecol;44(1):72-94, 2018 Jan.
[Is] ISSN:1573-1561
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Despite the many publications concerning the isolation of substances and the many reviews of marine natural products, some groups of organisms remain poorly studied, including "Polychaeta". In response, this review covers articles published through December 2016 that address marine natural products produced from polychaetes, with a focus on antipredatory strategies, competitors, fouling, and pathogens. A total of 121 compounds were isolated from 1934 to 2016, which includes halogenated aromatics, proteins, amino acids and Lumazine derivatives most notably-with a defensive function were found in the literature, most frequently in the families Sabellidae, Terebellidae, Glyceridae, and Nereididae. The period of highest discovery of natural products in defensive actions for the group was the 2000s. Polychaetes were addressed in 26 revisions of the total 51 articles analyzed and are less reported than other marine invertebrates such as sponges, cnidarians, mollusks, and tunicates. In sum, the present review provides a basis for future research on the marine chemical ecology of polychaetes.
[Mh] Termos MeSH primário: Organismos Aquáticos/química
Produtos Biológicos/química
[Mh] Termos MeSH secundário: Animais
Organismos Aquáticos/metabolismo
Produtos Biológicos/isolamento & purificação
Cnidários/química
Cnidários/metabolismo
Comportamento Consumatório/fisiologia
Equinodermos/química
Equinodermos/metabolismo
Fenômenos Ecológicos e Ambientais
Moluscos/química
Moluscos/metabolismo
Urocordados/química
Urocordados/metabolismo
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Nm] Nome de substância:
0 (Biological Products)
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180221
[Lr] Data última revisão:
180221
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171224
[St] Status:MEDLINE
[do] DOI:10.1007/s10886-017-0915-z


  10 / 4049 MEDLINE  
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[PMID]:29371626
[Au] Autor:Carradec Q; Pelletier E; Da Silva C; Alberti A; Seeleuthner Y; Blanc-Mathieu R; Lima-Mendez G; Rocha F; Tirichine L; Labadie K; Kirilovsky A; Bertrand A; Engelen S; Madoui MA; Méheust R; Poulain J; Romac S; Richter DJ; Yoshikawa G; Dimier C; Kandels-Lewis S; Picheral M; Searson S; Jaillon O; Aury JM; Karsenti E; Sullivan MB; Sunagawa S; Bork P; Not F; Hingamp P; Raes J; Guidi L; Ogata H; de Vargas C; Iudicone D; Bowler C; Wincker P; Tara Oceans Coordinators
[Ad] Endereço:CEA - Institut de Biologie François Jacob, Genoscope, Evry, 91057, France.
[Ti] Título:A global ocean atlas of eukaryotic genes.
[So] Source:Nat Commun;9(1):373, 2018 01 25.
[Is] ISSN:2041-1723
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:While our knowledge about the roles of microbes and viruses in the ocean has increased tremendously due to recent advances in genomics and metagenomics, research on marine microbial eukaryotes and zooplankton has benefited much less from these new technologies because of their larger genomes, their enormous diversity, and largely unexplored physiologies. Here, we use a metatranscriptomics approach to capture expressed genes in open ocean Tara Oceans stations across four organismal size fractions. The individual sequence reads cluster into 116 million unigenes representing the largest reference collection of eukaryotic transcripts from any single biome. The catalog is used to unveil functions expressed by eukaryotic marine plankton, and to assess their functional biogeography. Almost half of the sequences have no similarity with known proteins, and a great number belong to new gene families with a restricted distribution in the ocean. Overall, the resource provides the foundations for exploring the roles of marine eukaryotes in ocean ecology and biogeochemistry.
[Mh] Termos MeSH primário: Organismos Aquáticos
Eucariotos/genética
Células Eucarióticas/metabolismo
Metagenoma
Filogenia
Zooplâncton/genética
[Mh] Termos MeSH secundário: Sequência de Aminoácidos
Animais
Atlas como Assunto
Bactérias/classificação
Bactérias/genética
Biodiversidade
Ecossistema
Eucariotos/classificação
Células Eucarióticas/citologia
Metagenômica/métodos
Oceanos e Mares
Fitoplâncton/classificação
Fitoplâncton/genética
Água do Mar
Vírus/classificação
Vírus/genética
Zooplâncton/classificação
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180215
[Lr] Data última revisão:
180215
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180127
[St] Status:MEDLINE
[do] DOI:10.1038/s41467-017-02342-1



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