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[PMID]:27820302
[Au] Autor:Masapu D; Bansal S; Nanjundaiah GK; Surve RM
[Ad] Endereço:*Department of Anaesthesia, Sakra World Hospital †Department of Neuroanaesthesia National Institute of Mental Health and Neurosciences, Bangalore, India.
[Ti] Título:Extradural Hematoma With Unanticipated Difficult Intubation Due to Rhinoscleromatosis.
[So] Source:J Neurosurg Anesthesiol;29(1):67-68, 2017 01.
[Is] ISSN:1537-1921
[Cp] País de publicação:United States
[La] Idioma:eng
[Mh] Termos MeSH primário: Hematoma Epidural Craniano/complicações
Intubação Intratraqueal/métodos
Rinoscleroma/complicações
[Mh] Termos MeSH secundário: Adulto
Seres Humanos
Masculino
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170913
[Lr] Data última revisão:
170913
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161108
[St] Status:MEDLINE


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[PMID]:26778445
[Au] Autor:Gobel Y; Valette G; Delahaye L; Marianowski R
[Ad] Endereço:Service d'ORL et de chirurgie cervico-faciale, hôpital Morvan, CHRU de Brest, 5, avenue Foch, 29200 Brest, France.
[Ti] Título:A case of laryngeal rhinoscleroma.
[So] Source:Eur Ann Otorhinolaryngol Head Neck Dis;133(3):215-6, 2016 Jun.
[Is] ISSN:1879-730X
[Cp] País de publicação:France
[La] Idioma:eng
[Mh] Termos MeSH primário: Doenças da Laringe/diagnóstico
Doenças da Laringe/microbiologia
Rinoscleroma/diagnóstico
[Mh] Termos MeSH secundário: Epistaxe/microbiologia
Seres Humanos
Doenças da Laringe/terapia
Laringoscopia
Masculino
Meia-Idade
Obstrução Nasal/microbiologia
Rinoscleroma/terapia
[Pt] Tipo de publicação:CASE REPORTS; LETTER
[Em] Mês de entrada:1708
[Cu] Atualização por classe:170802
[Lr] Data última revisão:
170802
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160119
[St] Status:MEDLINE


  3 / 489 MEDLINE  
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[PMID]:26769262
[Au] Autor:Bigi A; Bartolomeo M; Costes V; Makeieff M
[Ad] Endereço:Département de chirurgie cervico-faciale, centre hospitalo universitaire, hôpital Gui-de-Chauliac, 80, avenue Augustin-Fliche, 34295 Montpellier cedex 5, France. Electronic address: a-bigi@chu-montpellier.fr.
[Ti] Título:Tracheal rhinoscleroma.
[So] Source:Eur Ann Otorhinolaryngol Head Neck Dis;133(1):51-3, 2016 Feb.
[Is] ISSN:1879-730X
[Cp] País de publicação:France
[La] Idioma:eng
[Ab] Resumo:INTRODUCTION: Tracheal rhinoscleroma is an infectious granulomatosis of the tracheobronchial tract caused by a Gram-negative bacillus. Exclusively tracheal involvement has been rarely reported in the literature. The purpose of this study was to report a case of subglottic stenosis secondary to rhinoscleroma. SUMMARY: A 46-year-old North African woman with no medical or surgical history presented with inspiratory dyspnoea that had been present for several years. Endoscopic examination under general anaesthesia revealed tracheal stenosis. Histological examination of mucosal biopsies demonstrated Mikulicz cells and culture of bacteriological samples taken during a second biopsy confirmed the diagnosis of rhinoscleroma. CO2 laser subglottic obstruction relief was performed and treatment with ofloxacin was initiated. No recurrence of tracheal stenosis was observed with a follow-up of 6 months. DISCUSSION: The diagnosis of rhinoscleroma is based on histological and bacteriological examination. Cultures are positive in 60% of cases, but negative cultures do not exclude the diagnosis of rhinoscleroma. Specific treatment consists of long-term antibiotic therapy, while surgery may be indicated for symptomatic treatment.
[Mh] Termos MeSH primário: Rinoscleroma/diagnóstico
Rinoscleroma/terapia
Doenças da Traqueia/microbiologia
Doenças da Traqueia/terapia
[Mh] Termos MeSH secundário: Antibacterianos/uso terapêutico
Dispneia/etiologia
Feminino
Seres Humanos
Terapia a Laser
Meia-Idade
Ofloxacino/uso terapêutico
Doenças da Traqueia/diagnóstico
Estenose Traqueal/etiologia
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Anti-Bacterial Agents); A4P49JAZ9H (Ofloxacin)
[Em] Mês de entrada:1612
[Cu] Atualização por classe:161230
[Lr] Data última revisão:
161230
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160116
[St] Status:MEDLINE


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[PMID]:26340893
[Au] Autor:Sahli M; Hemmaoui B; Errami N; Benariba F
[Ad] Endereço:Service ORL et chirurgie cervico-faciale, hôpital Militaire, Rabat, Morocco. Electronic address: dr.sahli.mohamed@hotmail.fr.
[Ti] Título:Laryngeal involvement of rhinoscleroma.
[So] Source:Eur Ann Otorhinolaryngol Head Neck Dis;133(4):293-4, 2016 Sep.
[Is] ISSN:1879-730X
[Cp] País de publicação:France
[La] Idioma:eng
[Mh] Termos MeSH primário: Doenças da Laringe/microbiologia
Rinoscleroma/diagnóstico
[Mh] Termos MeSH secundário: Adulto
Tosse/etiologia
Disfonia/etiologia
Seres Humanos
Doenças da Laringe/diagnóstico
Masculino
Obstrução Nasal/etiologia
[Pt] Tipo de publicação:CASE REPORTS; LETTER
[Em] Mês de entrada:1708
[Cu] Atualização por classe:170807
[Lr] Data última revisão:
170807
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:150906
[St] Status:MEDLINE


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[PMID]:26011421
[Au] Autor:Molumi CP; Dubey SP
[Ad] Endereço:Department of Ear, Nose and Throat, Port Moresby General Hospital, Boroko, Papua New Guinea.
[Ti] Título:Airway scleromas and their extensions.
[So] Source:ANZ J Surg;86(9):670-4, 2016 Sep.
[Is] ISSN:1445-2197
[Cp] País de publicação:Australia
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Scleroma is a rare, chronic, granulomatous infectious disease of the respiratory tract mucosa which begins in the nose and spreads to the respiratory tract and adjoining structures. We report on the extensions and the management of 134 cases of scleroma in the Highlands region of Papua New Guinea. METHODS: The charts and treatment records of 134 scleroma cases were retrospectively reviewed from 1995 to 2013. The staging, extensions, treatment and results of treatment were reviewed and analysed. RESULTS: Of the 134 cases, 72 (53.7%) were females and the age ranged from 6 to 65 years. The disease was confined to the nose and nasopharynx in 71 (53.0%) cases. Extension of the disease from the nose to the Eustachian tube occurred in nine (6.7%) cases and into the middle ear in four (3.0%) cases. Further extensions to the larynx and trachea were seen in 17 (12.7%) cases each and the bronchus in three (2.2%) cases. Primary laryngoscleroma without involvement of the nose and nasopharyngeal stenosis without laryngeal involvement were managed in 11 (8.2%) and nine (6.7%) cases respectively. Others cases treated were ethmoid scleroma with proptosis and scleroma involving the upper lip in one (0.75%) case each. Ninety-nine (74.9%) patients were treated medically while 35 (26.1%) patients required surgery. Cure were achieved in 83 (61.9%) cases treated medically and 26 (19.4%) had successful surgical outcome. CONCLUSION: Scleroma begins in the nose and when not arrested, extends causing obstruction to the airway and cosmetic deformity which requires surgical intervention.
[Mh] Termos MeSH primário: Obstrução das Vias Respiratórias/diagnóstico
Laringoscopia/métodos
Laringe/diagnóstico por imagem
Nasofaringe/diagnóstico por imagem
Procedimentos Cirúrgicos Otorrinolaringológicos/métodos
Rinoscleroma/diagnóstico
[Mh] Termos MeSH secundário: Adolescente
Adulto
Idoso
Obstrução das Vias Respiratórias/etiologia
Obstrução das Vias Respiratórias/cirurgia
Criança
Feminino
Seguimentos
Seres Humanos
Masculino
Meia-Idade
Estudos Retrospectivos
Rinoscleroma/complicações
Rinoscleroma/cirurgia
Resultado do Tratamento
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1702
[Cu] Atualização por classe:170817
[Lr] Data última revisão:
170817
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:150527
[St] Status:MEDLINE
[do] DOI:10.1111/ans.13183


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[PMID]:26930922
[Au] Autor:Gao Y; Wang Z; Zheng Y
[Ti] Título:[Rhinoscleroma disease accompanied with laryngotracheal stenosis: a case report].
[So] Source:Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi;29(21):1917-8, 2015 Nov.
[Is] ISSN:1001-1781
[Cp] País de publicação:China
[La] Idioma:chi
[Ab] Resumo:Rhinoscleroma disease accompanied with laryngotracheal stenosis as a main clinical manifestation is seldom. Here one case is reported. At the beginning, the patient had pharyngalgia and his swallowing was not smooth. After that, he had difficulty in breathing. Surgical therapy, antibiotics treatment and nutritional support were performed. The patient was cured.
[Mh] Termos MeSH primário: Laringe/fisiopatologia
Rinoscleroma/diagnóstico
Traqueia/fisiopatologia
[Mh] Termos MeSH secundário: Constrição Patológica
Deglutição
Seres Humanos
Masculino
Respiração
Rinoscleroma/complicações
Rinoscleroma/terapia
[Pt] Tipo de publicação:CASE REPORTS; ENGLISH ABSTRACT; JOURNAL ARTICLE
[Em] Mês de entrada:1607
[Cu] Atualização por classe:160302
[Lr] Data última revisão:
160302
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160303
[St] Status:MEDLINE


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[PMID]:26339415
[Au] Autor:Ahmed AR; El-Badawy ZH; Mohamed IR; Abdelhameed WA
[Ad] Endereço:Department of Pathology, Faculty of Medicine, Sohag University Sohag, Egypt.
[Ti] Título:Rhinoscleroma: a detailed histopathological diagnostic insight.
[So] Source:Int J Clin Exp Pathol;8(7):8438-45, 2015.
[Is] ISSN:1936-2625
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Rhinoscleroma (RS) is a chronic specific disease of nose and upper respiratory passages caused by Klebsiella rhinoscleromatis bacilli. It is endemic in Egypt and in sporadic areas worldwide. Diagnosis of RS depends on identification of the pathognomonic Mickulicz cells (MCs) which is most prominent during granulomatous phase but spares or absent during catarrhal or sclerotic phases of the disease. This study aimed to identify the potential diagnostic features of nasal RS when MCs are absent. Nasal biopsies from 125 patients complaining of chronic nasal symptoms were retrieved for this study; including 72 chronic non specific inflammatory lesions and 53 RS diagnosed by PAS and Geimsa stains. The detailed histological differences among the two groups were measured statistically. RS was frequently a bilateral disease (P < 0.05) of young age (P < 0.001) with a female predominance (P < 0.05) and usually associated with nasal crustations (P < 0.001). Five strong histological indicators of RS were specified by univariate binary logistic regression analyses including squamous metaplasia (OR 27.2, P < 0.0001), dominance of plasma cells (OR 12.75, P < 0.0001), Russell bodies (OR 8.83, P < 0.0001), neutrophiles (OR 3.7, P < 0.001) and absence of oesinophiles (OR 12.0, P < 0.0001). According to Multivariate analysis, the diagnostic features of RS in absence of MCs can be classified into major criteria including dominance of plasma cells infiltration and absence of oesinophiles and minor criteria including young age, female gender, bilateral nasal involvement, nasal crustation, squamous metaplasia, Russell bodies, and neutrophiles. The diagnostic model using the two major criteria confirmed or excluded RS in 84.3% of the investigated cases.
[Mh] Termos MeSH primário: Nariz/patologia
Rinoscleroma/patologia
[Mh] Termos MeSH secundário: Adolescente
Adulto
Fatores Etários
Idoso
Biópsia
Distribuição de Qui-Quadrado
Criança
Doença Crônica
Eosinófilos/patologia
Células Epiteliais/patologia
Feminino
Seres Humanos
Modelos Logísticos
Masculino
Metaplasia
Meia-Idade
Análise Multivariada
Neutrófilos/patologia
Plasmócitos/patologia
Valor Preditivo dos Testes
Estudos Retrospectivos
Fatores de Risco
Fatores Sexuais
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Em] Mês de entrada:1606
[Cu] Atualização por classe:150907
[Lr] Data última revisão:
150907
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:150905
[St] Status:MEDLINE


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[PMID]:26163236
[Au] Autor:Awad OG; Hammad MS
[Ad] Endereço:Otolaryngology, Head and Neck Department, Minia University, Minia, Egypt.
[Ti] Título:Topical mitomycin C as an adjunct to surgical debulking and medical treatment in rhinoscleroma.
[So] Source:Am J Rhinol Allergy;29(4):e95-9, 2015 Jul-Aug.
[Is] ISSN:1945-8932
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Rhinoscleroma is a chronic granuloma that is endemic in Egypt and is caused by gram-negative bacilli (Klebsiella rhinoscleromatis). The nasal mucosa is affected in almost all cases, which causes nasal obstruction, anosmia, and epistaxis. The disease usually passes through an atrophic stage (atrophic rhinitis) and a granulomatous stage before ending in the fibrotic stage, with possible bone destruction. OBJECTIVE: This study assessed the effect of topical mitomycin C (MMC) on reducing the recurrence of granulation tissue and intranasal adhesions after endoscopic debulking and continuous medical treatment of nasal rhinoscleroma. MATERIALS AND METHODS: This double-blind randomized clinical trial was performed with 30 patients who had rhinoscleroma (granulomatous and fibrotic stages). At the end of endoscopic debulking, meshes impregnated with MMC was placed in one nasal cavity for 5 minutes, while another meshes impregnated with saline solution were placed in the opposite side. Repeated meshes with MMC were placed in the same side during the follow-up period. Patients were followed up for 1 year. The recurrence of granulation tissue and the degree of intranasal adhesions were recorded and compared according to the Lund-Kennedy score. RESULTS: At 12 months' follow-up, among the total 30 patients, 30 MMC sides were compared with 30 control sides: 69% of MMC sides versus 32% of control sides had no recurrence of granulation tissue (p = 0.01) and 65% of MMC sides versus 24% of control sides had no recurrence of intranasal adhesions (p = 0.03). The Lund-Kennedy score decreased from 2.1 ± 0.64 to 0.8 ± 0.41 and from 2.3 ± 0.33 to 1.9 ± 0.20 in the MMC sides and control sides, respectively, with a nonstatistically significant lower incidence of intranasal adhesions in the MMC sides. CONCLUSION: Topical MMC may reduce granulation tissue and intranasal adhesion formation in patients with rhinoscleroma. Further studies with a larger number of samples and longer follow-up periods are recommended.
[Mh] Termos MeSH primário: Antibacterianos/uso terapêutico
Procedimentos Cirúrgicos de Citorredução
Mitomicina/administração & dosagem
Rinoscleroma/terapia
[Mh] Termos MeSH secundário: Administração Intranasal
Adolescente
Adulto
Procedimentos Cirúrgicos de Citorredução/métodos
Método Duplo-Cego
Feminino
Seguimentos
Seres Humanos
Masculino
Meia-Idade
Obstrução Nasal/terapia
Estudos Prospectivos
Recidiva
Rinoscleroma/microbiologia
Aderências Teciduais/terapia
Resultado do Tratamento
[Pt] Tipo de publicação:JOURNAL ARTICLE; RANDOMIZED CONTROLLED TRIAL
[Nm] Nome de substância:
0 (Anti-Bacterial Agents); 50SG953SK6 (Mitomycin)
[Em] Mês de entrada:1605
[Cu] Atualização por classe:150711
[Lr] Data última revisão:
150711
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:150712
[St] Status:MEDLINE
[do] DOI:10.2500/ajra.2015.29.4197


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[PMID]:26083225
[Au] Autor:Castanedo Cázares JP; Martinez Rosales KI
[Ad] Endereço:Hospital Central Dr. Ignacio Morones Prieto, San Luis Potosi, Mexico castanju@yahoo.com.
[Ti] Título:Images in Clinical Medicine. Rhinoscleroma.
[So] Source:N Engl J Med;372(25):e33, 2015 Jun 18.
[Is] ISSN:1533-4406
[Cp] País de publicação:United States
[La] Idioma:eng
[Mh] Termos MeSH primário: Nariz/patologia
Rinoscleroma/patologia
[Mh] Termos MeSH secundário: Seres Humanos
Klebsiella pneumoniae/isolamento & purificação
Masculino
Meia-Idade
Nariz/microbiologia
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Em] Mês de entrada:1506
[Cu] Atualização por classe:150618
[Lr] Data última revisão:
150618
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:150618
[St] Status:MEDLINE
[do] DOI:10.1056/NEJMicm1411602


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[PMID]:25933455
[Au] Autor:Nayak P; R C P; K V S; Desai D; Pandit S; Ingaleshwar PS
[Ad] Endereço:Department of Oral Pathology and Microbiology, A.J. Institute of Dental Sciences, Mangalore, Karnataka, India.
[Ti] Título:Rhinoscleroma of nose extruding into oral cavity.
[So] Source:J Coll Physicians Surg Pak;25 Suppl 1:S27-9, 2015 Apr.
[Is] ISSN:1681-7168
[Cp] País de publicação:Pakistan
[La] Idioma:eng
[Ab] Resumo:Rhinoscleroma (RS) is a rare chronic granulomatous disease of the upper airways affecting nasal cavity, nasopharynx, and paranasal sinuses. Klebsiella rhinoscleromatis is the causative agent of this infection and Mikulicz cells are specific to this lesion. RS is commonly seen in poorer regions such as Central Africa, South America, Middle East, India and Indonesia. It is predominantly found in rural areas and people with poor socio-economic conditions. Most patients present with chronic rhinitis, sneezing, headache and deviated nasal septum similar to current case. An association with oral cavity has not been reported previously, as per authors' knowledge. This report describes a rare case of RS of nasal cavity extending into the oral cavity.
[Mh] Termos MeSH primário: Klebsiella pneumoniae/isolamento & purificação
Boca/microbiologia
Nariz/microbiologia
Rinoscleroma/diagnóstico
[Mh] Termos MeSH secundário: Anti-Infecciosos/uso terapêutico
Ciprofloxacino/uso terapêutico
Feminino
Seres Humanos
Meia-Idade
Cavidade Nasal/patologia
Rinoscleroma/tratamento farmacológico
Rinoscleroma/cirurgia
Tomografia Computadorizada por Raios X
Resultado do Tratamento
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Anti-Infective Agents); 5E8K9I0O4U (Ciprofloxacin)
[Em] Mês de entrada:1609
[Cu] Atualização por classe:150502
[Lr] Data última revisão:
150502
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:150503
[St] Status:MEDLINE
[do] DOI:04.2015/JCPSP.S2729



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