Base de dados : MEDLINE
Pesquisa : C01.252.400.755 [Categoria DeCS]
Referências encontradas : 3426 [refinar]
Mostrando: 1 .. 10   no formato [Detalhado]

página 1 de 343 ir para página                         

  1 / 3426 MEDLINE  
              next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:29284250
[Au] Autor:Filioussis G; Theodoridis A; Papadopoulos D; Gelasakis AI; Vouraki S; Bramis G; Arsenos G
[Ad] Endereço:Laboratory of Microbiology & Infectious Diseases, School of Veterinary Medicine, Faculty of Health Sciences, Aristotle University, Thessaloniki, Greece. georgefilious@vet.auth.gr.
[Ti] Título:Serological prevalence of Coxiella burnetii in dairy goats and ewes diagnosed with adverse pregnancy outcomes in Greece.
[So] Source:Ann Agric Environ Med;24(4):702-705, 2017 Dec 23.
[Is] ISSN:1898-2263
[Cp] País de publicação:Poland
[La] Idioma:eng
[Ab] Resumo:INTRODUCTION: Coxiella burnetii is an obligatory intracellular bacterial pathogen causing the zoonotic disease Q fever. The most common reservoirs of C. burnetii are wild mammals, birds and ticks. Pregnant domestic ruminants infected with this bacterium are also a major source of human infection. MATERIAL AND METHODS: The serological prevalence of C. burnetii in goats and sheep diagnosed with adverse pregnancy outcomes was assessed by undertaking a survey on 800 dairy goats and 800 dairy ewes reared in four different regions of Greece (Macedonia, Thrace, Thessaly, and Peloponnese). A stratified sampling was carried out, taking also as a criterion the age of the animals. Serum antibodies were analyzed by a commercial ELISA according to the manufacturer's recommendations. RESULTS: Generally, there was a statistically significantly higher serological prevalence of C. burnetii (14.4%) in goats compared to sheep (8%). Serological prevalence was higher in adults (15.5% in goats and 8.5% in sheep) compared to yearlings (7.4% in goats and 4.6% in sheep). The prevalence increased significantly with age only in goats. Finally, all animals reared in Peloponnese had a prevalence significantly higher (21% in goats and 18% in sheep) than animals reared in the other three regions. CONCLUSIONS: To the best of the authors' knowledge, this is the first report that associates C. burnetii with reproductive disturbances of domestic ruminants in Greece. However, considering the importance of coxiellosis for public health, further investigations are required on its epidemiology regarding abortion, premature delivery, stillbirth and weak offspring in small ruminants, as well as in other domestic and wild animal species.
[Mh] Termos MeSH primário: Coxiella burnetii/imunologia
Doenças das Cabras/diagnóstico
Complicações na Gravidez/veterinária
Febre Q/veterinária
Doenças dos Ovinos/diagnóstico
[Mh] Termos MeSH secundário: Animais
Anticorpos Antibacterianos/imunologia
Coxiella burnetii/isolamento & purificação
Ensaio de Imunoadsorção Enzimática/veterinária
Feminino
Doenças das Cabras/epidemiologia
Doenças das Cabras/imunologia
Doenças das Cabras/microbiologia
Cabras
Grécia/epidemiologia
Masculino
Gravidez
Complicações na Gravidez/diagnóstico
Complicações na Gravidez/imunologia
Complicações na Gravidez/microbiologia
Resultado da Gravidez
Prevalência
Febre Q/diagnóstico
Febre Q/epidemiologia
Febre Q/imunologia
Estudos Soroepidemiológicos
Ovinos
Doenças dos Ovinos/epidemiologia
Doenças dos Ovinos/imunologia
Doenças dos Ovinos/microbiologia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Antibodies, Bacterial)
[Em] Mês de entrada:1801
[Cu] Atualização por classe:180105
[Lr] Data última revisão:
180105
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171230
[St] Status:MEDLINE


  2 / 3426 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:28455328
[Au] Autor:Joulié A; Rousset E; Gasqui P; Lepetitcolin E; Leblond A; Sidi-Boumedine K; Jourdain E
[Ad] Endereço:EPIA, INRA, VetAgro Sup, Saint-Genès-Champanelle, France.
[Ti] Título:Coxiella burnetii Circulation in a Naturally Infected Flock of Sheep: Individual Follow-Up of Antibodies in Serum and Milk.
[So] Source:Appl Environ Microbiol;83(13), 2017 Jul 01.
[Is] ISSN:1098-5336
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:The control of Q fever, a zoonotic disease caused by the bacterium, remains a scientific challenge. Domestic ruminants are considered the main reservoir, shedding essentially through parturition products during abortion or birth. Sheep are particularly frequently associated with human outbreaks, but there are insufficient field data to fully understand disease dynamics and to instigate efficient control measures. A longitudinal follow-up study of a naturally infected sheep flock was performed (i) to investigate relationships between seropositivity and bacterial shedding in the vaginal mucus, (ii) to describe the kinetics of antibodies, including responses to vaccination, (iii) to monitor maternal antibodies in ewe lambs, and (iv) to compare serological results for milk and serum samples. For 8 months, we collected blood samples every 3 weeks from 11 aborting and 26 nonaborting dairy ewes, 20 nonaborting suckler ewes, and 9 ewe lambs. Individual milk samples were also obtained from lactating females. All serum and milk samples were tested by enzyme-linked immunosorbent assay (ELISA), whereas vaginal swabs were tested by quantitative PCR. We found that some dairy females did not seroconvert despite shedding in their vaginal mucus. Overall, antibody levels in adult females were found to remain stable over time, with exceptions during the mating and lambing periods. Maternal antibodies decreased during the first month after birth. Interestingly, antibody levels in milk were correlated with those in serum. This study provides valuable field data that will help improve Q fever surveillance and within-flock management measures. Field data are necessary to improve the surveillance, diagnosis, and sanitary management of Q fever in livestock. Here, we provide extensive serological data obtained from serum and milk samples from infected and vaccinated ewes belonging to a naturally infected flock of sheep. We show that antibody levels are stable over time and seropositivity and vaginal shedding are not clearly correlated, whereas antibody levels in milk are strongly correlated with those in serum. Accordingly, we find that antibody levels in bulk tank milk are consistent with the variations observed in the serum of dairy females over time. We report the existence of maternal antibody transmission to ewe lambs and we show that the presence of maternal antibodies at birth does not prevent the development of a serological response to vaccination at the age of 4 months. Finally, we report that adult ewes generally seroconvert after vaccination, including during pregnancy.
[Mh] Termos MeSH primário: Anticorpos Antibacterianos/sangue
Coxiella burnetii/fisiologia
Leite/microbiologia
Febre Q/veterinária
Doenças dos Ovinos/microbiologia
Ovinos/microbiologia
[Mh] Termos MeSH secundário: Animais
Coxiella burnetii/genética
Coxiella burnetii/imunologia
Feminino
Seguimentos
Masculino
Leite/química
Febre Q/sangue
Febre Q/microbiologia
Ovinos/sangue
Doenças dos Ovinos/sangue
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Antibodies, Bacterial)
[Em] Mês de entrada:1712
[Cu] Atualização por classe:171225
[Lr] Data última revisão:
171225
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170430
[St] Status:MEDLINE


  3 / 3426 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:29176880
[Au] Autor:Tshokey T; Stenos J; Durrheim DN; Eastwood K; Nguyen C; Graves SR
[Ad] Endereço:Faculty of Health and Medicine, University of Newcastle, Newcastle, Australia.
[Ti] Título:Seroprevalence of rickettsial infections and Q fever in Bhutan.
[So] Source:PLoS Negl Trop Dis;11(11):e0006107, 2017 Nov.
[Is] ISSN:1935-2735
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: With few studies conducted to date, very little is known about the epidemiology of rickettsioses in Bhutan. Due to two previous outbreaks and increasing clinical cases, scrub typhus is better recognized than other rickettsial infections and Q fever. METHODOLOGY: A descriptive cross-sectional serosurvey was conducted from January to March 2015 in eight districts of Bhutan. Participants were 864 healthy individuals from an urban (30%) and a rural (70%) sampling unit in each of the eight districts. Serum samples were tested by microimmunofluorescence assay for rickettsial antibodies at the Australian Rickettsial Reference Laboratory. RESULTS: Of the 864 participants, 345 (39.9%) were males and the mean age of participants was 41.1 (range 13-98) years. An overall seroprevalence of 49% against rickettsioses was detected. Seroprevalence was highest against scrub typhus group (STG) (22.6%) followed by spotted fever group (SFG) rickettsia (15.7%), Q fever (QF) (6.9%) and typhus group (TG) rickettsia (3.5%). Evidence of exposure to multiple agents was also noted; the commonest being dual exposure to STG and SFG at 5%. A person's likelihood of exposure to STG and SFG rickettsia significantly increased with age and farmers were twice as likely to have evidence of STG exposure as other occupations. Trongsa district appeared to be a hotspot for STG exposure while Punakha district had the lowest STG exposure risk. Zhemgang had the lowest exposure risk to SFG rickettsia compared to other districts. People living at altitudes above 2000 meters were relatively protected from STG infections but this was not observed for SFG, TG or QF exposure. CONCLUSION: This seroprevalence study highlights the endemicity of STG and SFG rickettsia in Bhutan. The high seroprevalence warrants appropriate public health interventions, such as diagnostic improvements and clinical treatment guidelines. Future studies should focus on vector profiles, geospatial, bio-social and environmental risk assessment and preventive and control strategies.
[Mh] Termos MeSH primário: Anticorpos Antibacterianos/sangue
Febre Q/epidemiologia
Infecções por Rickettsia/epidemiologia
Tifo por Ácaros/epidemiologia
[Mh] Termos MeSH secundário: Adolescente
Adulto
Idoso
Idoso de 80 Anos ou mais
Butão/epidemiologia
Estudos Transversais
Demografia
Feminino
Seres Humanos
Modelos Logísticos
Masculino
Meia-Idade
Rickettsia
População Rural
Estudos Soroepidemiológicos
População Urbana
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Antibodies, Bacterial)
[Em] Mês de entrada:1712
[Cu] Atualização por classe:171219
[Lr] Data última revisão:
171219
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171128
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pntd.0006107


  4 / 3426 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:28462725
[Au] Autor:Boroduske A; Trofimova J; Kibilds J; Papule U; Sergejeva M; Rodze I; Grantina-Ievina L
[Ad] Endereço:Animal Disease Diagnostic Laboratory,Institute of Food Safety, Animal Health and Environment "BIOR",Riga,Latvia.
[Ti] Título:Coxiella burnetii (Q fever) infection in dairy cattle and associated risk factors in Latvia.
[So] Source:Epidemiol Infect;145(10):2011-2019, 2017 07.
[Is] ISSN:1469-4409
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:The purpose of this study was to describe prevalence and spatial distribution of Coxiella burnetii infections in dairy cow sheds in Latvia and to investigate risk factors contributing to C. burnetii infections. Blood serum samples from abortion cases from 1010 sheds have been tested by ELISA for the presence of C. burnetii antibodies and bulk tank milk (BTM) samples from 252 sheds have been tested by real time polymerase chain reaction and ELISA for the presence of C. burnetii DNA and antibodies. Prevalence of C. burnetii antibody-positive sheds in cases of abortion was 13·4%. A total of 10·7% and 13·2% of dairy cow sheds tested positive for the presence of C. burnetii DNA and antibodies in BTM, respectively. Two distinct areas of clustering of test-positive dairy cattle sheds were identified by spatial scan statistics of abortion cases and randomly sampled BTM samples. Three factors were identified as significantly contributing to the risk of C. burnetii DNA presence in BTM - number of cattle in shed (>200 animals/shed) (OR 3·93), location of the shed within risk area in Northern Latvia (OR 8·29) and for the first time, purchasing cattle from abroad has been shown to significantly increase risk (OR 2·68) of C. burnetii infection in dairy cows in Latvia.
[Mh] Termos MeSH primário: Aborto Animal/epidemiologia
Doenças dos Bovinos/epidemiologia
Coxiella burnetii/isolamento & purificação
Febre Q/veterinária
[Mh] Termos MeSH secundário: Aborto Animal/microbiologia
Animais
Bovinos
Doenças dos Bovinos/microbiologia
Coxiella burnetii/imunologia
DNA Bacteriano/análise
Indústria de Laticínios
Ensaio de Imunoadsorção Enzimática/veterinária
Feminino
Letônia/epidemiologia
Leite/microbiologia
Prevalência
Febre Q/epidemiologia
Febre Q/microbiologia
Fatores de Risco
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (DNA, Bacterial)
[Em] Mês de entrada:1706
[Cu] Atualização por classe:171125
[Lr] Data última revisão:
171125
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170503
[St] Status:MEDLINE
[do] DOI:10.1017/S0950268817000838


  5 / 3426 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:27776577
[Au] Autor:Candela MG; Caballol A; Atance PM
[Ad] Endereço:Área de Enfermedades Infecciosas,Departamento de Sanidad Animal,Facultad de Veterinaria,Universidad de Murcia,Murcia,Spain.
[Ti] Título:Wide exposure to Coxiella burnetii in ruminant and feline species living in a natural environment: zoonoses in a human-livestock-wildlife interface.
[So] Source:Epidemiol Infect;145(3):478-481, 2017 02.
[Is] ISSN:1469-4409
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Assessment of the role of wild and domestic hosts as potential reservoirs of misdiagnosed zoonoses, such as Q fever by Coxiella burnetii, is an important public health issue today both for wildlife conservation and management of disease in human-livestock-wildlife interface. This study used ELISA, an indirect antibody, to research (2003-2013) C. burnetii infection in seven free-living wild and domestic ruminant species and in European wildcats (Felis silvestris). The animals studied were 0 European wildcats, 21 Spanish ibex (Capra pyrenaica), 314 red deer (Cervus elaphus), 556 fallow deer (Dama dama), 211 European mouflon (Ovis aries musimon), eight roe deer (Capreolus capreolus), 407 bovines (Bos taurus) and 3739 sheep (Ovis aries). All the animals shared the same habitat in the Serranía de Cuenca Natural Park (Castile-La Mancha, Spain). The study area is an example of human-domestic-wildlife interface where people and domestic animals live in close proximity to wildlife. Observed C. burnetii seropositive frequencies were: 33·3% European wildcats, 23·8% Spanish ibex, 22·5% domestic sheep 1·5% red deer, 1·4% European mouflon, 0·24% cattle, 0·18% fallow deer and 0% roe deer. The study found a wide C. burnetii prevalence of previous and present exposure in wild and domestic ruminant hosts in the Serranía de Cuenca Natural Park and reports the first evidence of C. burnetii exposure in free-living European wildcats.
[Mh] Termos MeSH primário: Gatos
Febre Q/veterinária
Ruminantes
Zoonoses/epidemiologia
[Mh] Termos MeSH secundário: Animais
Coxiella burnetii
Ensaio de Imunoadsorção Enzimática
Feminino
Masculino
Febre Q/epidemiologia
Estudos Soroepidemiológicos
Espanha/epidemiologia
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Em] Mês de entrada:1706
[Cu] Atualização por classe:171125
[Lr] Data última revisão:
171125
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161026
[St] Status:MEDLINE
[do] DOI:10.1017/S0950268816002454


  6 / 3426 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:28873022
[Au] Autor:San-Miguel Ayanz JM; Garcia-Peña FJ; García-Lunar P; Ortega-Mora LM; Ruano MJ; Álvarez-García G; Collantes-Fernández E
[Ad] Endereço:1 ZOETIS , Madrid, Spain .
[Ti] Título:Seroprevalence of Leptospirosis, Brucellosis, and Q Fever in a Wild Red Deer (Cervus elaphus) Population Kept in a Fenced Reserve in Absence of Contact with Livestock.
[So] Source:Vector Borne Zoonotic Dis;17(10):692-697, 2017 Oct.
[Is] ISSN:1557-7759
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Wildlife health is of interest for public and animal health because wild animals have been identified as important sentinels for the surveillance for zoonotic pathogens. This work investigated Brucella spp., Coxiella burnetii, and Leptospira spp. infection seroprevalence in a free-ranging red deer population. The study was conducted in a fenced reserve with controlled hunting activity in central Spain with animals that did not have any contact with livestock. Sampling was performed at two time points before and 5 years after the implementation of new management measures, including a reduction in the red deer population in the reserve. In addition, the presence of Leptospira DNA was tested in placental and fetal samples from seropositive pregnant animals. Antibodies against Brucella and Coxiella were not detected in any sample. The seroprevalence of Leptospira was 9.4% (13/137) in the first sampling for serovars Canicola and Panama. Five years later, the prevalence rose to 38.5% (97/252) with Pomona, the only serovar detected. Animals older than 2 years (50%; 70/140) were more likely to be Pomona seropositive than animals ≤2 years old (25.2%; 27/107; p < 0.001). Leptospira DNA was not detected in any sample tested. In conclusion, wild red deer in this area without contact with livestock seem not to play an important role in Brucella spp. and C. burnetii maintenance. The high seroprevalence of Leptospira spp. serogroup Pomona could indicate a risk for people with narrow contact with these animals, but the carrier status was not assessed. Consequently, it is unknown if red deer would represent a risk for human infection. Considering that wild boar could be the source of infection to red deer, the role of wild boar in the spread of leptospirosis and the risk for human infection should be investigated.
[Mh] Termos MeSH primário: Brucelose/veterinária
Cervos/microbiologia
Leptospirose/veterinária
Febre Q/veterinária
[Mh] Termos MeSH secundário: Animais
Anticorpos Antibacterianos/sangue
Brucelose/sangue
Conservação dos Recursos Naturais
Feminino
Leptospira/classificação
Leptospirose/sangue
Gado
Masculino
Prevalência
Febre Q/sangue
Fatores de Risco
Estudos Soroepidemiológicos
Zoonoses
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Antibodies, Bacterial)
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171019
[Lr] Data última revisão:
171019
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170906
[St] Status:MEDLINE
[do] DOI:10.1089/vbz.2016.2105


  7 / 3426 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:28854806
[Au] Autor:Gerlach C; Skultéty L; Henning K; Neubauer H; Mertens K
[Ti] Título:Coxiella burnetii immunogenic proteins as a basis for new Q fever diagnostic and vaccine development.
[So] Source:Acta Virol;61(3):377-390, 2017.
[Is] ISSN:0001-723X
[Cp] País de publicação:Slovakia
[La] Idioma:eng
[Ab] Resumo:Coxiella burnetii is the etiological agent of the zoonosis Q fever, which can cause an acute or a chronic, life-threatening disease in humans. It presents a highly stable cell form, which persists in the environment and is transmitted via contaminated aerosols. Ruminants are considered as the main reservoir for human infections but are usually asymptomatic. Subclinical infection in these animals and the occurrence of serologically negative shedders hamper the identification of infected animals with the currently used diagnostic techniques. This suboptimal sensitivity limits reliable identification of infected animals as well as the well-timed implementation of countermeasures. This review summarizes compounds, focusing on C. burnetii seroreactive proteins, which were discovered in recent immunoproteomic studies. We analyzed these proteins regarding their localization, function, frequency of citation, differences seen in various host species as well as sensitivity and specificity. Finally, proteins useful for the development of new diagnostic test systems as well as subunit vaccines were discussed.
[Mh] Termos MeSH primário: Formação de Anticorpos/imunologia
Coxiella burnetii/imunologia
Febre Q/diagnóstico
Febre Q/imunologia
Vacinas/imunologia
[Mh] Termos MeSH secundário: Animais
Seres Humanos
Febre Q/microbiologia
Zoonoses/diagnóstico
Zoonoses/imunologia
Zoonoses/microbiologia
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Nm] Nome de substância:
0 (Vaccines)
[Em] Mês de entrada:1711
[Cu] Atualização por classe:171103
[Lr] Data última revisão:
171103
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170901
[St] Status:MEDLINE
[do] DOI:10.4149/av_2017_320


  8 / 3426 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:28854805
[Au] Autor:Sallay B; Vaculová T; Derdáková M; Rusnáková Taragelová V; Spitalská E; Skultéty L
[Ti] Título:Two mice models for transferability of zoonotic bacteria via tick vector.
[So] Source:Acta Virol;61(3):372-376, 2017.
[Is] ISSN:0001-723X
[Cp] País de publicação:Slovakia
[La] Idioma:eng
[Ab] Resumo:Spotted fever and typhus-related diseases caused by rickettsiae, Lyme borreliosis induced by spirochetes from Borrelia burgdorferii sensu lato complex, and Q fever evoked by Coxiella burnetii, are important zoonoses occurring worldwide. In order to study the pathogenesis of these infections, the efficacy of vaccines from the perspective of protection against the pathogens, pathogen - pathogen interactions during co-infections or pathogen-vector-host interrelationship, a suitable animal model should be established. In this study, we evaluated two mouse models - the C3H/N and Balb/c strains for susceptibility to infection and ability to transmit the pathogens via tick vector and to reveal the potential interactions between various bacterial tick-borne agents. Our results indicated that the C3H/N and Balb/c mice are well-accepted models of B. afzelii infection. However, they are not suitable for interaction studies with R. helvetica since the animals did not acquire rickettsiemia and do not transmit Rickettsia sp. to feeding ticks.
[Mh] Termos MeSH primário: Infecções Bacterianas/microbiologia
Doenças Transmitidas por Carrapatos/microbiologia
Carrapatos/microbiologia
Zoonoses/microbiologia
[Mh] Termos MeSH secundário: Animais
Infecções Bacterianas/imunologia
Coinfecção/imunologia
Coinfecção/microbiologia
Feminino
Interações Hospedeiro-Patógeno/fisiologia
Doença de Lyme/imunologia
Doença de Lyme/microbiologia
Camundongos
Camundongos Endogâmicos BALB C
Camundongos Endogâmicos C3H
Modelos Animais
Febre Q/imunologia
Febre Q/microbiologia
Rickettsia/imunologia
Rickettsia/patogenicidade
Infecções por Rickettsia/imunologia
Infecções por Rickettsia/microbiologia
Doenças Transmitidas por Carrapatos/imunologia
Carrapatos/imunologia
Vacinas/imunologia
Zoonoses/imunologia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Vaccines)
[Em] Mês de entrada:1711
[Cu] Atualização por classe:171103
[Lr] Data última revisão:
171103
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170901
[St] Status:MEDLINE
[do] DOI:10.4149/av_2017_319


  9 / 3426 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:28854803
[Au] Autor:Flores-Ramírez G; Kmetová M; Danchenko M; Spitalská E; Havlícek V; Skultéty L
[Ti] Título:Protein composition of the phase I Coxiella burnetii soluble antigen prepared by extraction with trichloroacetic acid.
[So] Source:Acta Virol;61(3):361-368, 2017.
[Is] ISSN:0001-723X
[Cp] País de publicação:Slovakia
[La] Idioma:eng
[Ab] Resumo:Q fever is a highly infectious, widespread airborne zoonosis caused by Coxiella burnetii bacterium. Humans usually acquire the disease by inhalation of contaminated aerosol produced by infected livestock. Vaccination is the most practical way for prevention and control of the disease in the exposed population. In this work, we reviewed the most important Q-fever outbreaks in Slovakia as well as the progress in vaccine development. One of them represents a soluble antigen complex produced by extraction with trichloroacetic acid from a highly purified C. burnetii phase I strain Nine Mile. It was developed at the Institute of Virology in Bratislava. The protein content of this vaccine was separated by gel electrophoresis and analyzed by mass spectrometry. The study has resulted in the identification of 39 bacterial proteins from which 12 were recognized as immunoreactive. Most of the proteins were involved in bacterium pathogenicity (41.6%) and cell wall maintenance (25%). Four of the immunoreactive proteins may possess the moonlighting activity. Definition of the vaccine components represents a prerequisite for vaccine standardization and approval by governmental authorities.
[Mh] Termos MeSH primário: Antígenos de Bactérias/química
Antígenos de Bactérias/imunologia
Proteínas de Bactérias/química
Proteínas de Bactérias/imunologia
Coxiella burnetii/imunologia
Ácido Tricloroacético/química
[Mh] Termos MeSH secundário: Animais
Surtos de Doenças
Seres Humanos
Febre Q/epidemiologia
Febre Q/imunologia
Febre Q/microbiologia
Eslováquia/epidemiologia
Vacinação/métodos
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Antigens, Bacterial); 0 (Bacterial Proteins); 5V2JDO056X (Trichloroacetic Acid)
[Em] Mês de entrada:1711
[Cu] Atualização por classe:171103
[Lr] Data última revisão:
171103
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170901
[St] Status:MEDLINE
[do] DOI:10.4149/av_2017_317


  10 / 3426 MEDLINE  
              first record previous record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:28854804
[Au] Autor:Szymanska-Czerwinska M; Jodelko A; Pluta M; Kowalik S; Niemczuk K
[Ti] Título:Seroprevalence of Coxiella burnetii among domestic ruminants and horses in Poland.
[So] Source:Acta Virol;61(3):369-371, 2017.
[Is] ISSN:0001-723X
[Cp] País de publicação:Slovakia
[La] Idioma:eng
[Ab] Resumo:Coxiella burnetii is the causative agent of Q fever. The cases of the disease are recorded in various species, including domestic animals. The aim of this investigation was to estimate the seroprevalence of C. burnetii in ruminants including cattle, sheep, goats, and horses. Totally, 2082 serum samples from 936 goats, 933 cattle, 89 sheep, and 124 horses, including various horse breeds, were tested by ELISA or complement fixation test. The examination revealed that Polish horses are seronegative while in the populations of cattle and small ruminants, seropositive animals are presented. The percentage of seropositive cattle, goats and sheep was 4.18, 6.30, and 13.48, respectively.
[Mh] Termos MeSH primário: Doenças dos Bovinos/epidemiologia
Coxiella burnetii/isolamento & purificação
Doenças das Cabras/enzimologia
Doenças dos Cavalos/epidemiologia
Doenças dos Ovinos/epidemiologia
[Mh] Termos MeSH secundário: Animais
Bovinos
Doenças dos Bovinos/microbiologia
Doenças das Cabras/microbiologia
Cabras
Doenças dos Cavalos/microbiologia
Cavalos
Polônia
Febre Q/microbiologia
Febre Q/veterinária
Ruminantes/metabolismo
Estudos Soroepidemiológicos
Ovinos
Doenças dos Ovinos/microbiologia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1711
[Cu] Atualização por classe:171103
[Lr] Data última revisão:
171103
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170901
[St] Status:MEDLINE
[do] DOI:10.4149/av_2017_318



página 1 de 343 ir para página                         
   


Refinar a pesquisa
  Base de dados : MEDLINE Formulário avançado   

    Pesquisar no campo  
1  
2
3
 
           



Search engine: iAH v2.6 powered by WWWISIS

BIREME/OPAS/OMS - Centro Latino-Americano e do Caribe de Informação em Ciências da Saúde