Base de dados : MEDLINE
Pesquisa : C01.703.534 [Categoria DeCS]
Referências encontradas : 7661 [refinar]
Mostrando: 1 .. 10   no formato [Detalhado]

página 1 de 767 ir para página                         

  1 / 7661 MEDLINE  
              next record last record
seleciona
para imprimir
Fotocópia
[PMID]:29185961
[Au] Autor:Galli M; Antinori S; Atzeni F; Meroni L; Riva A; Scirè C; Adorni F; Quartuccio L; Sebastiani M; Airò P; Bazzichi L; Cristini F; Del Bono V; Manfredi A; Viapiana O; De Rosa F; Favalli E; Petrelli E; Salvarani C; Govoni M; Corcione S; Scrivo R; Sarmati L; Lazzarin A; Grassi W; Mastroianni C; Gaeta GB; Ferraccioli G; Cutolo M; De Vita S; Lapadula G; Matucci-Cerinic M; Armignacco O; Sarzi-Puttini P
[Ad] Endereço:Clinica delle Malattie Infettive, Department of Biomedical and Clinical Sciences L. Sacco, University of Milan, Italy. massimo.galli@unimi.it.
[Ti] Título:Recommendations for the management of pulmonary fungal infections in patients with rheumatoid arthritis.
[So] Source:Clin Exp Rheumatol;35(6):1018-1028, 2017 Nov-Dec.
[Is] ISSN:0392-856X
[Cp] País de publicação:Italy
[La] Idioma:eng
[Ab] Resumo:Often life-threatening pulmonary fungal infections (PFIs) can occur in patients with rheumatoid arthritis (RA) receiving disease-modifying anti-rheumatic drugs (DMARDs). Most of the data concerning PFIs in RA patients come from case reports and retrospective case series. Of the ve most widely described PFIs, Pneumocystis jirovecii pneumonia (PJP) has rarely been seen outside Japan, pulmonary cryptococcosis has been diagnosed in only a small number of patients worldwide, pulmonary coccidioidomycosis has almost only been observed in endemic areas, the limited number of cases of pulmonary histoplasmosis have mainly occurred in the USA, and the rare cases of invasive pulmonary aspergillosis have only been encountered in leukopenic patients. Many aspects of the prophylaxis, diagnosis and treatment of PFIs in RA patients remain to be defined, as does the role of each DMARD in increasing the risk of infection, and the possibility of resuming biological and non-biological DMARD treatment after the infection has been cured. The recommendations for the management of PFIs described in this paper are the product of a consensus procedure promoted by the Italian group for the Study and Management of Infections in Patients with Rheumatic Diseases (the ISMIR group).
[Mh] Termos MeSH primário: Artrite Reumatoide/complicações
Pneumopatias Fúngicas/tratamento farmacológico
[Mh] Termos MeSH secundário: Antirreumáticos/efeitos adversos
Coccidioidomicose/tratamento farmacológico
Criptococose/tratamento farmacológico
Histoplasmose/tratamento farmacológico
Seres Humanos
Pneumonia por Pneumocystis/tratamento farmacológico
Aspergilose Pulmonar/tratamento farmacológico
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Nm] Nome de substância:
0 (Antirheumatic Agents)
[Em] Mês de entrada:1803
[Cu] Atualização por classe:180301
[Lr] Data última revisão:
180301
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171130
[St] Status:MEDLINE


  2 / 7661 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:29212355
[Au] Autor:Sassi C; Stanzani M; Lewis RE; Facchini G; Bazzocchi A; Cavo M; Battista G
[Ad] Endereço:1 Department of Experimental, Diagnostic and Specialty Medicine (DIMES), Division of Radiology, S.Orsola-Malpighi Hospital, University of Bologna , Bologna , Italy.
[Ti] Título:The utility of contrast-enhanced hypodense sign for the diagnosis of pulmonary invasive mould disease in patients with haematological malignancies.
[So] Source:Br J Radiol;91(1083):20170220, 2018 Feb.
[Is] ISSN:1748-880X
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:OBJECTIVE: The hypodense sign (HyS) on CT imaging is highly suggestive of pulmonary invasive mould disease (IMD) in patients with haematological malignancies, but its diagnostic utility has not been systematically evaluated on contrast-enhanced CT. The objective of this study was to compare the diagnostic performance of the HyS to other common CT findings in a cohort of haematology patients with proven, probable or possible IMD based on European Organization for Research and Treatment of Cancer/Mycoses Study Group criteria. METHODS: We analysed the diagnostic performance of the HyS to other common CT signs among 127 neutropenic patients with haematological malignancies submitted to both non-contrast-enhanced and contrast-enhanced CT scans of the lungs, including CT pulmonary angiography. RESULTS: The HyS was detected in 15.7% of patients imaged without contrast, and 44.1% after contrast administration. A contrast-aided HyS was detected in 86.6, 78.0 and 15.5% of patients with European Organization for Research and Treatment of Cancer/Mycoses Study Group proven, probable and possible IMD, respectively. When analysed per clinical diagnosis (proven, probable and highly possible IMD-i.e. no alternative diagnosis to mould disease reached), the contrast-enhanced HyS was as sensitive as the halo sign but significantly more specific [halo sign 0.56, 95% CI (0.39-0.71) vs HyS 0.98, 95% CI (0.87-1.00)]. Only the vessel occlusion sign was more sensitive [0.97, 95% CI (0.91-0.99)] and specific [0.97, 95% CI (0.86-0.99)] than the HyS for IMD diagnosis. CONCLUSION: The high specificity of the HyS strongly supports the diagnosis of pulmonary IMD in neutropenic patients, and is highly suggestive breakthrough fungal disease in patients on mould-active antifungal prophylaxis. Advances in knowledge: This is the first systematic analysis of the hypodense sign on contrast-enhanced CT; the sign can support the diagnosis of IMD when other CT signs are uncertain.
[Mh] Termos MeSH primário: Neoplasias Hematológicas/complicações
Pneumopatias Fúngicas/diagnóstico por imagem
Tomografia Computadorizada por Raios X/métodos
[Mh] Termos MeSH secundário: Adulto
Idoso
Meios de Contraste
Feminino
Seres Humanos
Hospedeiro Imunocomprometido
Pneumopatias Fúngicas/tratamento farmacológico
Masculino
Meia-Idade
Radiografia Torácica
Estudos Retrospectivos
Sensibilidade e Especificidade
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Contrast Media)
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180226
[Lr] Data última revisão:
180226
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:171208
[St] Status:MEDLINE
[do] DOI:10.1259/bjr.20170220


  3 / 7661 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
[PMID]:27771978
[Au] Autor:Schreiber MP; Shorr AF
[Ad] Endereço:a Department of Internal Medicine , Section of Pulmonary Disease & Critical Care , 110 Irving St NW, Washington , DC , USA.
[Ti] Título:Challenges and opportunities in the treatment of ventilator-associated pneumonia.
[So] Source:Expert Rev Anti Infect Ther;15(1):23-32, 2017 01.
[Is] ISSN:1744-8336
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:INTRODUCTION: Ventilator-associated pneumonia (VAP) is a distinct clinical entity characterized by an onset after 48 hours of the application of mechanical ventilation (MV). Protocols exist to aid in the prevention of VAP, but this infection carries a devastating impact on patient morbidity and potentially mortality. Areas covered: In this review we present key concepts from existing guidelines to aid clinicians. Challenges remain in defining this disease and, most importantly appropriate empiric antimicrobial treatment is the main determinant of outcome. We highlight that the selection of initial antibiotics is critical, as VAP can by caused by a broad array of drug resistant organisms (DROs), the appropriate duration of treatment for VAP is an evolving concept, but may, in part, be guided by biomarkers, and provide focus on diagnostic challenges, initial therapies and treatment strategies for VAP. Both traditional and novel antimicrobials are presented, including developments in the modes of delivery. Expert commentary: The clinical approach to VAP continues to evolve. Recent evidence regarding the changes in microbiology, diagnostics approaches, and treatment strategies for VAP are important for clinicians to remain informed of to provide optimal patient care.
[Mh] Termos MeSH primário: Antibacterianos/uso terapêutico
Cuidados Críticos/métodos
Pneumopatias Fúngicas/tratamento farmacológico
Pneumonia Bacteriana/tratamento farmacológico
Pneumonia Associada à Ventilação Mecânica/diagnóstico
Pneumonia Associada à Ventilação Mecânica/tratamento farmacológico
[Mh] Termos MeSH secundário: Antibacterianos/administração & dosagem
Antibacterianos/efeitos adversos
Infecções por Bactérias Gram-Negativas/diagnóstico
Infecções por Bactérias Gram-Negativas/tratamento farmacológico
Infecções por Bactérias Gram-Negativas/microbiologia
Infecções por Bactérias Gram-Negativas/mortalidade
Infecções por Bactérias Gram-Positivas/diagnóstico
Infecções por Bactérias Gram-Positivas/tratamento farmacológico
Infecções por Bactérias Gram-Positivas/microbiologia
Seres Humanos
Pneumopatias Fúngicas/diagnóstico
Pneumopatias Fúngicas/microbiologia
Pneumopatias Fúngicas/mortalidade
Pneumonia Bacteriana/diagnóstico
Pneumonia Bacteriana/microbiologia
Pneumonia Bacteriana/mortalidade
Pneumonia Associada à Ventilação Mecânica/microbiologia
Pneumonia Associada à Ventilação Mecânica/mortalidade
Guias de Prática Clínica como Assunto
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Nm] Nome de substância:
0 (Anti-Bacterial Agents)
[Em] Mês de entrada:1710
[Cu] Atualização por classe:180213
[Lr] Data última revisão:
180213
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161101
[St] Status:MEDLINE


  4 / 7661 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:29382032
[Au] Autor:Lu CT; Zhang RM; Wang H; Kong FW; Wu WB; Gong LB; Zhang M
[Ad] Endereço:Department of General Thoracic Surgery, Xuzhou Central Hospital Affiliated to Southeast University.
[Ti] Título:A rare case of cavitary lung cancer complicated with mycotic pneumonia and bullous emphysema: A case report and review of the literature.
[So] Source:Medicine (Baltimore);96(47):e8927, 2017 Nov.
[Is] ISSN:1536-5964
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:RATIONALE: The accurate diagnosis and staging of cavitary lung cancer is challenging but essential for the choice of therapy; therefore, the differential diagnosis of cystic pulmonary lesions needs to be elucidated. PATIENT CONCERNS: A patient was admitted with multifocal thin-walled cystic lesions in chest computed tomography. DIAGNOSES: The patient had been diagnosed as heterogeneous bullous emphysema pathologically about 3 years ago. His diagnosis turned out to be metastatic cavitary lung cancer complicated with fungal pneumonia this time. INTERVENTIONS: The patient underwent lung volume reduction surgery during his first hospitalization. Concurrent systemic chemotherapy and whole brain radiotherapy were administered after the diagnosis of cystic lung cancer. OUTCOMES: The patient was lost to follow-up after the chemoradiotherapy. LESSONS: Cavitary lung cancer should always be kept in mind during differential diagnosis of pulmonary cystic lesions. Pathological diagnosis by biopsy and surgery could be considered to avoid delayed treatment of malignancy.
[Mh] Termos MeSH primário: Enfisema/microbiologia
Pneumopatias Fúngicas/complicações
Neoplasias Pulmonares/microbiologia
Pneumonia/microbiologia
[Mh] Termos MeSH secundário: Diagnóstico Diferencial
Enfisema/diagnóstico
Seres Humanos
Perda de Seguimento
Neoplasias Pulmonares/diagnóstico
Masculino
Meia-Idade
Pneumonia/diagnóstico
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE; REVIEW
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180207
[Lr] Data última revisão:
180207
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:180201
[St] Status:MEDLINE
[do] DOI:10.1097/MD.0000000000008927


  5 / 7661 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:29040281
[Au] Autor:Arango JC; Puerta-Arias JD; Pino-Tamayo PA; Salazar-Peláez LM; Rojas M; González Á
[Ad] Endereço:Medical and Experimental Mycology Group, Corporación para Investigaciones Biológicas (CIB)-Universidad de Antioquia, Medellín, Colombia.
[Ti] Título:Impaired anti-fibrotic effect of bone marrow-derived mesenchymal stem cell in a mouse model of pulmonary paracoccidioidomycosis.
[So] Source:PLoS Negl Trop Dis;11(10):e0006006, 2017 Oct.
[Is] ISSN:1935-2735
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Bone marrow-derived mesenchymal stem cells (BMMSCs) have been consider as a promising therapy in fibrotic diseases. Experimental models suggest that BMMSCs may be used as an alternative therapy to treat chemical- or physical-induced pulmonary fibrosis. We investigated the anti-fibrotic potential of BMMSCs in an experimental model of lung fibrosis by infection with Paracoccidioides brasiliensis. BMMSCs were isolated and purified from BALB/c mice using standardized methods. BALB/c male mice were inoculated by intranasal infection of 1.5x106 P. brasiliensis yeasts. Then, 1x106 BMMSCs were administered intra venous at 8th week post-infection (p.i.). An additional group of mice was treated with itraconazole (ITC) two weeks before BMMSCs administration. Animals were sacrificed at 12th week p.i. Histopathological examination, fibrocytes counts, soluble collagen and fibrosis-related genes expression in lungs were evaluated. Additionally, human fibroblasts were treated with homogenized lung supernatants (HLS) to determine induction of collagen expression. Histological analysis showed an increase of granulomatous inflammatory areas in BMMSCs-treated mice. A significant increase of fibrocytes count, soluble collagen and collagen-3α1, TGF-ß3, MMP-8 and MMP-15 genes expression were also observed in those mice. Interestingly, when combined therapy BMMSCs/ITC was used there is a decrease of TIMP-1 and MMP-13 gene expression in infected mice. Finally, human fibroblasts stimulated with HLS from infected and BMMSCs-transplanted mice showed a higher expression of collagen I. In conclusion, our findings indicate that late infusion of BMMSCs into mice infected with P. brasiliensis does not have any anti-fibrotic effect; possibly because their interaction with the fungus promotes collagen expression and tissue remodeling.
[Mh] Termos MeSH primário: Células da Medula Óssea
Pneumopatias Fúngicas/terapia
Transplante de Células-Tronco Mesenquimais
Células Mesenquimais Estromais
Paracoccidioidomicose/terapia
Fibrose Pulmonar/etiologia
[Mh] Termos MeSH secundário: Animais
Modelos Animais de Doenças
Fibrose/prevenção & controle
Pneumopatias Fúngicas/patologia
Masculino
Camundongos
Camundongos Endogâmicos BALB C
Paracoccidioidomicose/patologia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1711
[Cu] Atualização por classe:171110
[Lr] Data última revisão:
171110
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171018
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pntd.0006006


  6 / 7661 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:28889900
[Au] Autor:Hountras P; Cajigas H
[Ad] Endereço:Department of Pulmonary and Critical Care Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL. Electronic address: peter.hountras@northwestern.edu.
[Ti] Título:A 62-Year-Old Woman With Wheezing, Respiratory Failure, and an Abnormal CT Scan.
[So] Source:Chest;152(3):e73-e76, 2017 Sep.
[Is] ISSN:1931-3543
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:CASE PRESENTATION: A previously healthy 62-year-old woman was transferred to the ICU from the medical ward with acute bronchospastic respiratory failure requiring intubation and mechanical ventilation. Four weeks before, the patient was vacationing in Arizona and acquired a mildly productive cough as well as mild dyspnea. She presented to an urgent care facility and was diagnosed with community-acquired pneumonia. She received a 5-day course of azithromycin, with partial improvement of her symptoms. The patient returned home 1 week prior to admission, reporting worsening dyspnea, chest pressure, cough, and fever. The patient was admitted to the medical ward, and treatment for unresolved pneumonia was begun with levofloxacin, an inhaled short-acting beta agonist, and oral prednisone. Despite this treatment, the patient experienced severe respiratory distress with audible wheezing as well as increased work of breathing. She was intubated for acute hypoxemic respiratory failure and transferred to the ICU.
[Mh] Termos MeSH primário: Coccidioidomicose/diagnóstico por imagem
Pneumopatias Fúngicas/diagnóstico por imagem
Insuficiência Respiratória/microbiologia
Sons Respiratórios/etiologia
[Mh] Termos MeSH secundário: Coccidioidomicose/complicações
Coccidioidomicose/terapia
Cuidados Críticos
Feminino
Seres Humanos
Pneumopatias Fúngicas/complicações
Pneumopatias Fúngicas/terapia
Meia-Idade
Respiração Artificial
Insuficiência Respiratória/diagnóstico por imagem
Insuficiência Respiratória/terapia
Sons Respiratórios/diagnóstico
Tomografia Computadorizada por Raios X
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170922
[Lr] Data última revisão:
170922
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:170912
[St] Status:MEDLINE


  7 / 7661 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:28797398
[Au] Autor:Patterson J; Graham D; George A; Will M; Sutter D
[Ad] Endereço:Department of Pediatrics, San Antonio Military Medical Center, JBSA Fort Sam Houston, TX.
[Ti] Título:Right Middle Lobe Collapse and Pleural Effusion in an 18-Year-Old Man.
[So] Source:Chest;152(2):e33-e38, 2017 Aug.
[Is] ISSN:1931-3543
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:An 18-year-old African American male subject presented to an acute care clinic with 3 days of productive cough, chills, pleuritic right chest pain, sore throat with hoarseness, congestion, and intermittent shortness of breath. He recently relocated to Texas from Georgia to undergo basic military training. He denied any other recent travel or contact with persons with pulmonary TB or other respiratory illnesses. His medical history was significant for glucose-6-phosphate dehydrogenase deficiency and sickle cell trait.
[Mh] Termos MeSH primário: Histoplasmose/diagnóstico
Pneumopatias Fúngicas/diagnóstico
Mediastinite/microbiologia
Derrame Pleural/microbiologia
Atelectasia Pulmonar/microbiologia
Esclerose/microbiologia
[Mh] Termos MeSH secundário: Adolescente
Histoplasma
Histoplasmose/diagnóstico por imagem
Seres Humanos
Pneumopatias Fúngicas/diagnóstico por imagem
Masculino
Mediastinite/diagnóstico por imagem
Derrame Pleural/diagnóstico por imagem
Atelectasia Pulmonar/diagnóstico por imagem
Esclerose/diagnóstico por imagem
Tomografia Computadorizada por Raios X
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170911
[Lr] Data última revisão:
170911
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:170812
[St] Status:MEDLINE


  8 / 7661 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:28532447
[Au] Autor:Gao LW; Jiao AX; Wu XR; Zhao SY; Ma Y; Liu G; Yin J; Xu BP; Shen KL
[Ad] Endereço:Respiratory Department, Beijing Children's Hospital, Capital Medical University, Beijing, China.
[Ti] Título:Clinical characteristics of disseminated cryptococcosis in previously healthy children in China.
[So] Source:BMC Infect Dis;17(1):359, 2017 May 22.
[Is] ISSN:1471-2334
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Disseminated cryptococcosis is a rare and fatal disease, and limited data exist regarding it in children. This study aimed to investigate the clinical characteristics of disseminated cryptococcosis in previously healthy children in China. METHODS: Hospitalized patients with disseminated cryptococcosis were enrolled during January 1996 to December 2015 in Beijing Children's Hospital, Capital Medical University, China. Data on clinical manifestations, laboratory tests, treatment, and prognosis were evaluated. RESULTS: A total of 52 pediatric patients with no underlying disease were enrolled, including 38 boys and 14 girls. Only 10 cases had a history of exposure to pigeon droppings. Fever, cough, and hepatomegaly were 3 main manifestations of disseminated cryptococcosis. However, headache was more common in patients with central nervous system (CNS) invasion than in patients with non-CNS invasion (P < 0.05). Lung (96.2%, 50/52) was the most commonly invaded organ, but only 9.6% (5/52) of patients had respiratory signs. The most common findings on chest imaging were hilar or mediastinal lymphadenopathy (46.8%, 22/47), and nodules (44.7%, 21/47), including small nodules in a scattered distribution (57.1%, 12/21) or miliary distribution (42.9%, 9/25), especially localized in subpleural area. Subsequent invasion occurred in the CNS, abdomen lymph nodes, liver, spleen, peripheral lymph nodes, and skin. In all patients, 42.3% (22/52) and 51.9% (27/52) had elevated eosinophils or IgE, respectively. The positive rate of serum cryptococcal antigen was higher, especially in patients with CNS invasion (approximately 83.3%), than with other primary methods used for pathogen detection, including cerebrospinal fluid (CSF) cryptococcal antigen, cultures of blood, bone marrow, or CSF, and CSF ink staining. The overall mortality rate of pediatric patients in our study was 11.5% (6/52). Some cases had long-term sequela, including hydrocephalus, cirrhosis, or blindness. CONCLUSIONS: Disseminated cryptococcosis can occur in previously healthy or immunocompetent children in China. Lung and CNS were most commonly invaded by this disease. Furthermore, most cases usually showed no obvious or specific symptoms or signs, and therefore pediatricians should pay more careful attention to identify this disease.
[Mh] Termos MeSH primário: Antifúngicos/uso terapêutico
Criptococose/diagnóstico
Criptococose/etiologia
[Mh] Termos MeSH secundário: Antígenos de Fungos/sangue
Criança
Pré-Escolar
China
Tosse/microbiologia
Criptococose/tratamento farmacológico
Eosinófilos/patologia
Feminino
Febre/microbiologia
Cefaleia/microbiologia
Hepatomegalia/microbiologia
Seres Humanos
Hidrocefalia/microbiologia
Pneumopatias Fúngicas/diagnóstico
Pneumopatias Fúngicas/microbiologia
Linfonodos/patologia
Masculino
Prognóstico
Radiografia Torácica
Estudos Retrospectivos
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Antifungal Agents); 0 (Antigens, Fungal)
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170911
[Lr] Data última revisão:
170911
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170524
[St] Status:MEDLINE
[do] DOI:10.1186/s12879-017-2450-5


  9 / 7661 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:28528060
[Au] Autor:Afolayan O; Copeland H; Zaheer S; Wallen JM
[Ad] Endereço:Department of Surgery, University of Washington, Seattle, Washington.
[Ti] Título:Pulmonary Mucormycosis Treated With Lobectomy.
[So] Source:Ann Thorac Surg;103(6):e531-e533, 2017 Jun.
[Is] ISSN:1552-6259
[Cp] País de publicação:Netherlands
[La] Idioma:eng
[Ab] Resumo:A 57 year old man was referred from an outside facility for an unresolving pneumonia. Imaging of the chest demonstrated a right lung mass with a consolidation in the middle lobe, pleural effusion, and mediastinal lymphadenopathy. Cytologic examination of cultures from the bronchoscopy and thoracentesis did not yield a definitive diagnosis. Video-assisted thoracoscopic surgery (VATS) was performed because of a retained hemothorax and a suggestive lesion. Biopsy specimens obtained during VATS were consistent with mucormycosis. The patient underwent a middle lobectomy and pleurectomy without any adverse event. When bronchoscopy and thoracentesis cannot provide a diagnosis, thoracoscopic pleural biopsy can be the next step in the diagnosis of mucormycosis.
[Mh] Termos MeSH primário: Pneumopatias Fúngicas/diagnóstico
Pneumopatias Fúngicas/cirurgia
Mucormicose/diagnóstico
Mucormicose/cirurgia
Pneumonectomia
Cirurgia Torácica Vídeoassistida
[Mh] Termos MeSH secundário: Seres Humanos
Masculino
Meia-Idade
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Em] Mês de entrada:1708
[Cu] Atualização por classe:170821
[Lr] Data última revisão:
170821
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:170522
[St] Status:MEDLINE


  10 / 7661 MEDLINE  
              first record previous record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:28476105
[Au] Autor:Lehur AC; Zielinski M; Pluvy J; Grégoire V; Diamantis S; Bleibtreu A; Rioux C; Picard A; Vallois D
[Ad] Endereço:Infectious and Tropical Diseases Department, University Hospital Bichat-Claude Bernard, APHP, 46 rue Henri Huchard, 75018, Paris, France.
[Ti] Título:Case of disseminated histoplasmosis in a HIV-infected patient revealed by nasal involvement with maxillary osteolysis.
[So] Source:BMC Infect Dis;17(1):328, 2017 May 05.
[Is] ISSN:1471-2334
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Disseminated Histoplasmosis (DH) is a rare manifestation of Acquired Immune Deficiency Syndrome (AIDS) in European countries. Naso-maxillar osteolysis due to Histoplasma capsulatum var. capsulatum (Hcc) is unusual in endemic countries and has never been reported in European countries. Differential diagnoses such as malignant tumors, cocaine use, granulomatosis, vasculitis and infections are more frequently observed and could delay and/or bias the final diagnosis. CASE PRESENTATION: We report the case of an immunocompromised patient infected by Human Immunodeficiency Virus (HIV) with naso-maxillar histoplasmosis in a non-endemic country. Our aim is to describe the clinical presentation, the diagnostic and therapeutic issues. A 53-year-old woman, originated from Haiti, was admitted in 2016 for nasal deformation with alteration of general condition evolving for at least 6 months. HIV infection was diagnosed in 2006 and classified at AIDS stage in 2008 due to cytomegalovirus infection associated with pulmonary histoplasmosis. At admission, CD4 cell count was 9/mm . Surgical biopsies were performed and ruled out differential or associated diagnoses. Mycological cultures identified Hcc and Blood Polymerase Chain Reaction (PCR) for Hcc was positive. The patient was given daily Amphothericin B liposomal infusion during 1 month. Hcc PCR became negative in the blood under treatment, and then oral switch by itraconazole was introduced. Antiretroviral treatment was reintroduced after a 3-week histoplasmosis treatment. Normalization of naso-maxillar mucosa enabled a palatal prosthesis. CONCLUSION: Naso-maxillar histoplasmosis is extremely rare; this is the first case ever reported in a non-endemic country. Differential diagnoses must be ruled out by conducting microbiologic tools and histological examinations on surgical biopsies. Early antifungal treatment should be initiated in order to prevent DH severe outcomes.
[Mh] Termos MeSH primário: Infecções Oportunistas Relacionadas com a AIDS/etiologia
Histoplasmose/tratamento farmacológico
Histoplasmose/etiologia
Osteólise/etiologia
[Mh] Termos MeSH secundário: Infecções Oportunistas Relacionadas com a AIDS/tratamento farmacológico
Infecções Oportunistas Relacionadas com a AIDS/microbiologia
Síndrome de Imunodeficiência Adquirida/tratamento farmacológico
Fármacos Anti-HIV/uso terapêutico
Antifúngicos/uso terapêutico
Contagem de Linfócito CD4
Infecções por Citomegalovirus/diagnóstico
Infecções por Citomegalovirus/etiologia
Diagnóstico Diferencial
Feminino
Infecções por HIV/complicações
Infecções por HIV/tratamento farmacológico
Haiti
Histoplasmose/diagnóstico
Seres Humanos
Hospedeiro Imunocomprometido
Itraconazol/uso terapêutico
Pneumopatias Fúngicas/diagnóstico
Pneumopatias Fúngicas/tratamento farmacológico
Pneumopatias Fúngicas/etiologia
Doenças Maxilares/tratamento farmacológico
Doenças Maxilares/etiologia
Doenças Maxilares/microbiologia
Meia-Idade
Osteólise/microbiologia
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Anti-HIV Agents); 0 (Antifungal Agents); 304NUG5GF4 (Itraconazole)
[Em] Mês de entrada:1708
[Cu] Atualização por classe:170807
[Lr] Data última revisão:
170807
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170507
[St] Status:MEDLINE
[do] DOI:10.1186/s12879-017-2419-4



página 1 de 767 ir para página                         
   


Refinar a pesquisa
  Base de dados : MEDLINE Formulário avançado   

    Pesquisar no campo  
1  
2
3
 
           



Search engine: iAH v2.6 powered by WWWISIS

BIREME/OPAS/OMS - Centro Latino-Americano e do Caribe de Informação em Ciências da Saúde