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[PMID]:28110790
[Au] Autor:Zhang X; Wang J; Mao Y; Xi J; Yu Y; Liu W
[Ad] Endereço:State Key Laboratory of Agrobiotechnology, Department of Biochemistry and Molecular Biology, College of Biological Sciences, China Agricultural University, Beijing 100193, PR China.
[Ti] Título:Induction and suppression of type I interferon responses by mink enteritis virus in CRFK cells.
[So] Source:Vet Microbiol;199:8-14, 2017 Feb.
[Is] ISSN:1873-2542
[Cp] País de publicação:Netherlands
[La] Idioma:eng
[Ab] Resumo:Mink enteritis virus (MEV) is one of the most important viral pathogens causing serious disease in mink. Type I interferon (IFN) plays a critical role in antiviral innate immunity and, for successful infection, many viruses have evolved evasive strategies against it. Here, we show that MEV infection does not evoke IFN or interferon-stimulated genes (ISGs) responses in feline kidney (CRFK) cells, and that MEV suppresses IFN production in both poly I:C-stimulated and untreated cells. In CRFK cells pre-exposure to IFN, show that infection with, and replication of, MEV remain unaffected. This inhibition appears to be mediated by the MEV nonstructural protein (NS1) with its ORI-binding domain playing a major role.
[Mh] Termos MeSH primário: Panleucopenia Felina/imunologia
Interferon Tipo I/imunologia
Vírus da Enterite do Vison/fisiologia
[Mh] Termos MeSH secundário: Animais
Gatos
Linhagem Celular
Regulação da Expressão Gênica/efeitos dos fármacos
Indutores de Interferon/farmacologia
Poli I-C/farmacologia
Proteínas não Estruturais Virais/metabolismo
Replicação Viral
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Interferon Inducers); 0 (Interferon Type I); 0 (Viral Nonstructural Proteins); O84C90HH2L (Poly I-C)
[Em] Mês de entrada:1702
[Cu] Atualização por classe:171116
[Lr] Data última revisão:
171116
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170124
[St] Status:MEDLINE


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[PMID]:27502089
[Au] Autor:Mukhopadhyay HK; Nookala M; Thangamani NR; Sivaprakasam A; Antony PX; Thanislass J; Srinivas MV; Pillai RM
[Ad] Endereço:1 Department of Veterinary Microbiology, Rajiv Gandhi Institute of Veterinary Education and Research, Puducherry, India.
[Ti] Título:Molecular characterisation of parvoviruses from domestic cats reveals emergence of newer variants in India.
[So] Source:J Feline Med Surg;19(8):846-852, 2017 Aug.
[Is] ISSN:1532-2750
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Objectives The present study was undertaken to characterise the viral polypeptide 2 (VP2) gene of parvovirus from domestic cats in India. Methods The faecal samples from diarrhoeic/healthy domestic cats were collected from different geographical regions of India for screening by PCR assay followed by sequence analysis of the VP2 gene. Results Canine parvovirus (CPV)/feline panleukopenia virus (FPV) infections were found in 12 (11.3%) of 106 faecal samples tested. Two new CPV-2a (297Ala and Asn426) and three FPV strains were identified by VP2 gene analysis. Several unique and existing amino acid mutations were found, suggesting continuous evolution and emergence of newer variants. The phylogenetic analysis of the CPV sequences revealed that the two new CPV-2a strains from Mumbai (MC8) and Puducherry (P15) were clustered together in a single clade but had evolved independently and were ancestrally related to Chinese CPV-2a isolates. The FPV sequences (T-C-6 and T-C-1) from Thrissur, Kerala, formed a different clade (FPV clade) and were closely related to each other and had an ancestral relationship with an FPV isolate from the USA. Another FPV isolate from Goa (GC1) was positioned in the same clade but had evolved independently. Conclusions and relevance Detection of CPV in both diarrhoeic/healthy cats and the occurrence of FPV infection in a vaccinated cat provide new insights into parvovirus infections in cats in India.
[Mh] Termos MeSH primário: Proteínas do Capsídeo/genética
Vírus da Panleucopenia Felina/isolamento & purificação
Panleucopenia Felina/virologia
Parvovirus Canino/isolamento & purificação
[Mh] Termos MeSH secundário: Animais
Gatos
Fezes/virologia
Vírus da Panleucopenia Felina/genética
Feminino
Índia
Masculino
Mutação
Parvovirus Canino/genética
Filogenia
Reação em Cadeia da Polimerase/veterinária
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Capsid Proteins); 0 (capsid protein VP2, parvovirus B19)
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171018
[Lr] Data última revisão:
171018
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160810
[St] Status:MEDLINE
[do] DOI:10.1177/1098612X16661375


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[PMID]:27830988
[Au] Autor:Poncelet L; Garigliany M; Ando K; Franssen M; Desmecht D; Brion JP
[Ad] Endereço:a Laboratory of Anatomy, Biomechanics and Organogenesis, Faculty of Medicine, Université Libre de Bruxelles , Brussels , Belgium.
[Ti] Título:Cell cycle S phase markers are expressed in cerebral neuron nuclei of cats infected by the Feline Panleukopenia Virus.
[So] Source:Cell Cycle;15(24):3482-3489, 2016 Dec 16.
[Is] ISSN:1551-4005
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:The cell cycle-associated neuronal death hypothesis, which has been proposed as a common mechanism for most neurodegenerative diseases, is notably supported by evidencing cell cycle effectors in neurons. However, in naturally occurring nervous system diseases, these markers are not expressed in neuron nuclei but in cytoplasmic compartments. In other respects, the Feline Panleukopenia Virus (FPV) is able to complete its cycle in mature brain neurons in the feline species. As a parvovirus, the FPV is strictly dependent on its host cell reaching the cell cycle S phase to start its multiplication. In this retrospective study on the whole brain of 12 cats with naturally-occurring, FPV-associated cerebellar atrophy, VP2 capsid protein expression was detected by immunostaining not only in some brain neuronal nuclei but also in neuronal cytoplasm in 2 cats, suggesting that viral mRNA translation was still occurring. In these cats, double immunostainings demonstrated the expression of cell cycle S phase markers cyclin A, cdk2 and PCNA in neuronal nuclei. Parvoviruses are able to maintain their host cells in S phase by triggering the DNA damage response. S139 phospho H2A1, a key player in the cell cycle arrest, was detected in some neuronal nuclei, supporting that infected neurons were also blocked into the S phase. PCR studies did not support a co-infection with an adeno or herpes virus. ERK1/2 nuclear accumulation was observed in some neurons suggesting that the ERK signaling pathway might be involved as a mechanism driving these neurons far into the cell cycle.
[Mh] Termos MeSH primário: Biomarcadores/metabolismo
Núcleo Celular/metabolismo
Cérebro/patologia
Vírus da Panleucopenia Felina/fisiologia
Panleucopenia Felina/patologia
Panleucopenia Felina/virologia
Neurônios/patologia
Fase S
[Mh] Termos MeSH secundário: Animais
Anticorpos Antivirais/metabolismo
Especificidade de Anticorpos
Pareamento de Bases
Proteínas do Capsídeo/metabolismo
Gatos
Núcleo Celular/enzimologia
DNA Viral/metabolismo
MAP Quinases Reguladas por Sinal Extracelular/metabolismo
Vírus da Panleucopenia Felina/genética
Feminino
Genes Virais
Células HEK293
Seres Humanos
Imuno-Histoquímica
Masculino
Neurônios/virologia
Reação em Cadeia da Polimerase
Reprodutibilidade dos Testes
Tálamo/metabolismo
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Antibodies, Viral); 0 (Biomarkers); 0 (Capsid Proteins); 0 (DNA, Viral); EC 2.7.11.24 (Extracellular Signal-Regulated MAP Kinases)
[Em] Mês de entrada:1706
[Cu] Atualização por classe:171110
[Lr] Data última revisão:
171110
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161111
[St] Status:MEDLINE
[do] DOI:10.1080/15384101.2016.1249546


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[PMID]:27380652
[Au] Autor:Lane EP; Brettschneider H; Caldwell P; Oosthuizen A; Dalton DL; du Plessis L; Steyl J; Kotze A
[Ad] Endereço:Department of Research and Scientific Services, National Zoological Gardens of South Africa. emily@nzg.ac.za.
[Ti] Título:Feline panleukopaenia virus in captive non-domestic felids in South Africa.
[So] Source:Onderstepoort J Vet Res;83(1):a1099, 2016 Jun 09.
[Is] ISSN:2219-0635
[Cp] País de publicação:South Africa
[La] Idioma:eng
[Ab] Resumo:An outbreak of feline panleukopaenia virus (FPLV) infection was diagnosed by pathology, electron microscopy and polymerase chain reaction (PCR) in vaccinated captive-bred subadult cheetahs in South Africa. Subsequent to this disease outbreak, 12 cases of FPLV diagnosed on histology were confirmed by PCR in captive African black-footed cat, caracal, cheetah, lion, ocelot and serval. Phylogenetic analyses of the viral capsid protein gene on PCR-positive samples, vaccine and National Center for Biotechnology Information (NCBI) reference strains identified a previously unknown strain of FPLV, present since at least 2006, that differs from both the inactivated and the modified live vaccine strains. A previously described South African strain from domestic cats and cheetahs was identified in a serval. Surveys of FPLV strains in South African felids are needed to determine the geographical and host species distribution of this virus. Since non-domestic species may be reservoirs of parvoviruses, and since these viruses readily change host specificity, the risks of FPLV transmission between captive-bred and free-ranging carnivores and domestic cats and dogs warrant further research.
[Mh] Termos MeSH primário: Surtos de Doenças/veterinária
Felidae
Vírus da Panleucopenia Felina/isolamento & purificação
Panleucopenia Felina/epidemiologia
[Mh] Termos MeSH secundário: Acinonyx
Animais
Proteínas do Capsídeo/genética
Gatos
Panleucopenia Felina/diagnóstico
Panleucopenia Felina/patologia
Panleucopenia Felina/virologia
Vírus da Panleucopenia Felina/genética
Feminino
Masculino
Filogenia
Reação em Cadeia da Polimerase/veterinária
Análise de Sequência de DNA/veterinária
África do Sul/epidemiologia
Vacinação
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (Capsid Proteins)
[Em] Mês de entrada:1612
[Cu] Atualização por classe:161230
[Lr] Data última revisão:
161230
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160707
[St] Status:MEDLINE
[do] DOI:10.4102/ojvr.v83i1.1099


  5 / 239 MEDLINE  
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[PMID]:26967127
[Au] Autor:Avendaño R; Barrueta F; Soto-Fournier S; Chavarría M; Monge O; Gutiérrez-Espeleta GA; Chaves A
[Ad] Endereço:1 Centro Nacional de Innovaciones Biotecnológicas (CENIBiot), CeNAT-CONARE, 1174-1200 San José, Costa Rica;
[Ti] Título:Canine Distemper Virus in Wild Felids of Costa Rica.
[So] Source:J Wildl Dis;52(2):373-7, 2016 04 28.
[Is] ISSN:1943-3700
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Several highly infectious diseases can be transmitted through feces and cause elevated mortality among carnivore species. One such infectious agent, canine distemper virus (CDV; Paramyxoviridae: Morbillivirus), has been reported to affect wild carnivores, among them several felid species. We screened free-ranging and captive wild carnivores in Costa Rica for CDV. Between 2006 and 2012, we collected 306 fecal samples from 70 jaguars (Panther onca), 71 ocelots ( Leopardus pardalis ), five jaguarundis (Puma yaguaroundi), 105 pumas ( Puma concolor ), five margays ( Leopardus wiedii ), 23 coyotes ( Canis latrans ), and 27 undetermined Leopardus spp. We found CDV in six individuals: one captive jaguarundi (rescued in 2009), three free-ranging ocelots (samples collected in 2012), and two free-ranging pumas (samples collected in 2007). Phylogenetic analyses were performed using sequences of the phosphoprotein (P) gene. We provide evidence of CDV in wild carnivores in Costa Rica and sequence data from a Costa Rican CDV isolate, adding to the very few sequence data available for CDV isolates from wild Central American carnivores.
[Mh] Termos MeSH primário: Animais Selvagens
Vírus da Cinomose Canina/isolamento & purificação
Felidae
Panleucopenia Felina/virologia
[Mh] Termos MeSH secundário: Animais
Gatos
Costa Rica/epidemiologia
Vírus da Cinomose Canina/genética
Panleucopenia Felina/epidemiologia
Filogenia
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171103
[Lr] Data última revisão:
171103
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160312
[St] Status:MEDLINE
[do] DOI:10.7589/2015-02-041


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[PMID]:26895627
[Au] Autor:Garigliany M; Gilliaux G; Jolly S; Casanova T; Bayrou C; Gommeren K; Fett T; Mauroy A; Lévy E; Cassart D; Peeters D; Poncelet L; Desmecht D
[Ad] Endereço:Department of Morphology and Pathology, University of Liège, Liège, Belgium. mmgarigliany@ulg.ac.be.
[Ti] Título:Feline panleukopenia virus in cerebral neurons of young and adult cats.
[So] Source:BMC Vet Res;12:28, 2016 Feb 19.
[Is] ISSN:1746-6148
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Perinatal infections with feline panleukopenia virus (FPV) have long been known to be associated with cerebellar hypoplasia in kittens due to productive infection of dividing neuroblasts. FPV, like other parvoviruses, requires dividing cells to replicate which explains the usual tropism of the virus for the digestive tract, lymphoid tissues and bone marrow in older animals. RESULTS: In this study, the necropsy and histopathological analyses of a series of 28 cats which died from parvovirus infection in 2013 were performed. Infections were confirmed by real time PCR and immunohistochemistry in several organs. Strikingly, while none of these cats showed cerebellar atrophy or cerebellar positive immunostaining, some of them, including one adult, showed a bright positive immunostaining for viral antigens in cerebral neurons (diencephalon). Furthermore, infected neurons were negative by immunostaining for p27(Kip1), a cell cycle regulatory protein, while neighboring, uninfected, neurons were positive, suggesting a possible re-entry of infected neurons into the mitotic cycle. Next-Generation Sequencing and PCR analyses showed that the virus infecting cat brains was FPV and presented a unique substitution in NS1 protein sequence. Given the role played by this protein in the control of cell cycle and apoptosis in other parvoviral species, it is tempting to hypothesize that a cause-to-effect between this NS1 mutation and the capacity of this FPV strain to infect neurons in adult cats might exist. CONCLUSIONS: This study provides the first evidence of infection of cerebral neurons by feline panleukopenia virus in cats, including an adult. A possible re-entry into the cell cycle by infected neurons has been observed. A mutation in the NS1 protein sequence of the FPV strain involved could be related to its unusual cellular tropism. Further research is needed to clarify this point.
[Mh] Termos MeSH primário: Cérebro/virologia
Vírus da Panleucopenia Felina/isolamento & purificação
Panleucopenia Felina/virologia
Neurônios/virologia
[Mh] Termos MeSH secundário: Animais
Antígenos Virais/análise
Gatos
DNA Viral/análise
Feminino
Masculino
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Antigens, Viral); 0 (DNA, Viral)
[Em] Mês de entrada:1609
[Cu] Atualização por classe:160222
[Lr] Data última revisão:
160222
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160221
[St] Status:MEDLINE
[do] DOI:10.1186/s12917-016-0657-0


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[PMID]:24923754
[Au] Autor:Stuetzer B; Hartmann K
[Ad] Endereço:Clinic of Small Animal Medicine, Faculty of Veterinary Medicine, Ludwig-Maximilians- Universität Muenchen, Munich, Germany. Electronic address: b.stuetzer@gmx.de.
[Ti] Título:Feline parvovirus infection and associated diseases.
[So] Source:Vet J;201(2):150-5, 2014 Aug.
[Is] ISSN:1532-2971
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Feline panleukopenia, caused by the single-stranded DNA virus feline parvovirus (FPV), is a highly contagious and often lethal disease of cats and other Felidae. FPV, but also canine parvovirus (CPV) can be isolated from both healthy and diseased cats. In Germany, CPV was detected in only approximately 10% of feline samples, but in Southeast Asia, reports estimated that up to approximately 80% of diseased cats were infected with CPV. Infection spreads rapidly, especially in cells with high mitotic activity, such as bone marrow, lymphoid tissue and intestinal crypt cells. Anorexia, vomiting, diarrhoea, neutropenia and lymphopenia are common in clinically affected cases. In utero or neonatal infection can result in cerebellar hypoplasia. Depending on the severity of clinical signs, mortality ranges from 25 to 100%. Effective vaccination and thorough disinfection are of the utmost importance in the prevention of disease transmission in multi-cat households and animal shelters. If clinical signs develop, supportive treatment should be commenced. The efficacy of feline recombinant interferon and FPV antibodies has not been clearly demonstrated. Commercially available vaccines should induce protective immunity when administered according to current guidelines. Recent studies suggest that in some kittens, maternally derived antibodies (MDA) can persist for much longer than has been previously recognised. FPV serum antibody tests are available, but protection status needs to be interpreted with caution in kittens with MDA and a negative titre in adult cats does not necessarily denote lack of protection.
[Mh] Termos MeSH primário: Vírus da Panleucopenia Felina/fisiologia
Panleucopenia Felina
[Mh] Termos MeSH secundário: Animais
Gatos
Panleucopenia Felina/diagnóstico
Panleucopenia Felina/epidemiologia
Panleucopenia Felina/terapia
Panleucopenia Felina/virologia
Vírus da Panleucopenia Felina/imunologia
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Em] Mês de entrada:1504
[Cu] Atualização por classe:151119
[Lr] Data última revisão:
151119
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:140614
[St] Status:MEDLINE


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[PMID]:24525403
[Au] Autor:Sun JZ; Wang J; Wang S; Yuan D; Birame BM; Li Z; Yi B; Liu W
[Ad] Endereço:State Key Laboratory of Agrobiotechnology, Department of Biochemistry and Molecular Biology, College of Biological Sciences, China Agricultural University, Beijing 100193, China.
[Ti] Título:MicroRNA profile analysis of a feline kidney cell line before and after infection with mink enteritis virus.
[So] Source:Gene;539(2):224-9, 2014 Apr 15.
[Is] ISSN:1879-0038
[Cp] País de publicação:Netherlands
[La] Idioma:eng
[Ab] Resumo:MicroRNAs (miRNAs) are small regulatory RNAs that play a significant role in eukaryotes by targeting mRNAs for cleavage or translational repression. Recent studies have also shown them to be associated with cellular changes following viral infection. Mink enteritis virus (MEV) is one of the most important viral pathogens in the mink industry. To study the involvement of miRNAs in the MEV infection process, we used Illumina's ultrahigh throughput approach to sequencing miRNA libraries from the feline kidney (F81) cell line before and after infection with MEV. Using this bioinformatics approach we identified 196 known mammalian miRNA orthologs belonging to 152 miRNA families in F81 cells. Additionally, 97 miRNA*s of these miRNAs were detected. As well as known miRNAs, 384 and 398 novel miRNA precursor candidates were identified in uninfected and MEV-infected F81 cells respectively that have not been reported in other mammals. In MEV-infected cells 3 miRNAs were significantly down-regulated and 4 up-regulated including 3 significantly. The majority (12 of 16) of randomly selected miRNA expression profiles by qRT-PCR were consistent with those identified by deep sequencing. A total of 88 miRNAs were predicted to target interferon-associated genes; 6 appear to target the 3'UTR of MEV-specific receptor transferring receptor mRNAs; and 8 to target the MEV mRNA coding region. No miRNAs coded by MEV itself were detected.
[Mh] Termos MeSH primário: Biomarcadores/metabolismo
Panleucopenia Felina/genética
Perfilação da Expressão Gênica
Rim/metabolismo
MicroRNAs/genética
Enterite Viral do Vison/genética
Vírus da Enterite do Vison/patogenicidade
[Mh] Termos MeSH secundário: Animais
Gatos
Células Cultivadas
Biologia Computacional
Panleucopenia Felina/virologia
Rim/virologia
Enterite Viral do Vison/virologia
Análise de Sequência com Séries de Oligonucleotídeos
RNA Mensageiro/genética
Reação em Cadeia da Polimerase em Tempo Real
Reação em Cadeia da Polimerase Via Transcriptase Reversa
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (Biomarkers); 0 (MicroRNAs); 0 (RNA, Messenger)
[Em] Mês de entrada:1405
[Cu] Atualização por classe:151119
[Lr] Data última revisão:
151119
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:140215
[St] Status:MEDLINE


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[PMID]:24496322
[Au] Autor:Mende K; Stuetzer B; Truyen U; Hartmann K
[Ad] Endereço:Clinic of Small Animal Medicine, Ludwig-Maximilians-University of Munich, Munich, Germany katherina.mende@googlemail.com.
[Ti] Título:Evaluation of an in-house dot enzyme-linked immunosorbent assay to detect antibodies against feline panleukopenia virus.
[So] Source:J Feline Med Surg;16(10):805-11, 2014 Oct.
[Is] ISSN:1532-2750
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Measuring antibody titres to determine a cat's immunity to core diseases instead of just administering annual vaccinations has not been established in Germany so far. An in-house test kit for the detection of antibodies against feline panleukopenia virus (FPV), feline herpesvirus-1 and feline calicivirus-- the ImmunoComb Feline VacciCheck--is now available in several European countries. The aim of this study was to assess the quality of the ImmunoComb Feline VacciCheck to determine antibodies by comparing it to a gold standard. The test is aimed for use in practice to assist decision-making when performing an individual health assessment to see whether a cat is potentially unprotected against FPV and requires FPV vaccination. Sera from 347 cats were included in the study. For antibody detection, haemagglutination inhibition (HI) was performed as gold standard. Sensitivity, specificity and positive and negative predictive values of the ImmunoComb Feline VacciCheck were determined for three different HI titre cut-off points (1:20, 1:40, 1:80). In comparison to the HI, the ImmunoComb Feline VacciCheck showed a sensitivity of 79%, 83% and 87%, and a specificity of 89%, 86% and 81%, respectively. Specificity of the ImmunoComb Feline VacciCheck, which was considered the most important parameter, was acceptable in comparison to HI. Especially when considering an antibody titre of 1:20 sufficient for protection (eg, in an adult animal), the ImmunoComb Feline VacciCheck can be recommended for use in veterinary practice.
[Mh] Termos MeSH primário: Anticorpos Antivirais/sangue
Ensaio de Imunoadsorção Enzimática/veterinária
Vírus da Panleucopenia Felina/imunologia
Panleucopenia Felina/diagnóstico
[Mh] Termos MeSH secundário: Animais
Gatos
Ensaio de Imunoadsorção Enzimática/métodos
Panleucopenia Felina/imunologia
Panleucopenia Felina/prevenção & controle
Feminino
Masculino
Sensibilidade e Especificidade
[Pt] Tipo de publicação:EVALUATION STUDIES; JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Antibodies, Viral)
[Em] Mês de entrada:1507
[Cu] Atualização por classe:151119
[Lr] Data última revisão:
151119
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:140206
[St] Status:MEDLINE
[do] DOI:10.1177/1098612X14520812


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[PMID]:24463992
[Au] Autor:Jack SC; Sutton D; Bhogle A; Spibey N; Francis M
[Ad] Endereço:MSD Animal Health, Walton Manor, Walton, Milton Keynes, Buckinghamshire MK7 7AJ, UK;
[Ti] Título:FPL-vaccinated cats are protected from CPV2c and CPV2b challenge.
[So] Source:Vet Rec;174(6):146, 2014 Feb 08.
[Is] ISSN:2042-7670
[Cp] País de publicação:England
[La] Idioma:eng
[Mh] Termos MeSH primário: Panleucopenia Felina/prevenção & controle
Parvovirus Canino/imunologia
Vacinas Virais/administração & dosagem
[Mh] Termos MeSH secundário: Animais
Gatos
Variação Genética
Parvovirus Canino/genética
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Viral Vaccines)
[Em] Mês de entrada:1506
[Cu] Atualização por classe:140210
[Lr] Data última revisão:
140210
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:140128
[St] Status:MEDLINE
[do] DOI:10.1136/vr.102037



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