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[PMID]:28552738
[Au] Autor:Taghipour M; Saffarrian A; Ghaffarpasand F; Azarpira N
[Ad] Endereço:Department of Neurosurgery, Shiraz University of Medical Sciences, Shiraz, Iran.
[Ti] Título:Dumbbell-Shape Hydatid Cyst of Meckel Cave Extending to Cerebellopontine Angle and Middle Fossa; Surgical Technique and Outcome of Rare Case.
[So] Source:World Neurosurg;104:1049.e7-1049.e10, 2017 Aug.
[Is] ISSN:1878-8769
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Cerebral hydatid cyst is among the rare presentations of echinococcosis. Almost all the reported cases of intracranial hydatid cysts are in the cortical regions (parietal lobe in the territory of the middle cerebral artery), and all have been removed surgically using the water jet dissection technique. However, in locations in which there are several neuronal structures, such as the cerebellopontine angle, this method might not be applicable. CASE DESCRIPTION: A 62-year-old lady presented to our outpatient clinic with left-sided facial deviation, inability to close the eyes, and diplopia since a month before. She was diagnosed with having a dumbbell-shape lesion in the Meckel cave extending to the left cerebellopontine angle and middle fossa just lateral to the cavernous sinus. As it was adherent to the surrounding structures, we evacuated the contents using a fine needle and then dissected the cyst totally. The patient's symptoms alleviated after the surgery, and there was no residue. After the 2-year follow-up, our patient does not have recurrence. CONCLUSIONS: The Meckel cave and cerebellopontine angle are rare locations for hydatid cysts, and the surgical technique is different due to adhesion of the cyst to several neuronal structures (lower cranial nerve, brainstem, and cerebellum). Needle aspiration along with dissection of the cyst microsurgically is recommended in similar cases.
[Mh] Termos MeSH primário: Infecções Parasitárias do Sistema Nervoso Central/cirurgia
Ângulo Cerebelopontino/cirurgia
Fossa Craniana Média/cirurgia
Equinococose/cirurgia
Procedimentos Neurocirúrgicos
[Mh] Termos MeSH secundário: Infecções Parasitárias do Sistema Nervoso Central/diagnóstico por imagem
Ângulo Cerebelopontino/diagnóstico por imagem
Fossa Craniana Média/diagnóstico por imagem
Equinococose/diagnóstico por imagem
Feminino
Escala de Resultado de Glasgow
Seres Humanos
Imagem por Ressonância Magnética
Meia-Idade
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170925
[Lr] Data última revisão:
170925
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170530
[St] Status:MEDLINE


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[PMID]:28434960
[Au] Autor:Das KK; Gosal JS; Singh S; Mehrotra A; Jaiswal A; Jaiswal S; Kumar R
[Ad] Endereço:Department of Neurosurgery, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India. Electronic address: drkuntalkantidas@gmail.com.
[Ti] Título:Solitary Cysticercal Cyst Inside the Blake's Pouch Remnant of Mega Cisterna Magna with Associated Aqueductal Stenosis: Clinical and Management Implications.
[So] Source:World Neurosurg;102:693.e1-693.e5, 2017 Jun.
[Is] ISSN:1878-8769
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Intraventricular and subarachnoid forms represent the relatively complex, albeit uncommon, manifestations of central nervous system involvement by cysticercal cysts. Cysticercal encystation inside the Blake's pouch remnant of mega cisterna magna (MCM) remains an extremely rare clinical scenario that, to the best of our knowledge, has not been reported previously. CASE PRESENTATION: A 12-year-old boy presented with acute worsening and subsequent spontaneous resolution of his compensated hydrocephalus. Neuroimaging revealed features consistent with a MCM with septum inside, indicating remnants of the embryologic fourth ventricular diverticulum, the Blake's pouch. It also revealed a free-floating intact cysticercal cyst inside the MCM limited by the septum with aqueductal stenosis. The spontaneous clinicoradiologic resolution of hydrocephalus raised the possibility of ball valve obstruction of the cerebrospinal fluid outflow, i.e., Bruns syndrome. We successfully treated this patient with endoscopic extraction of the viable cysticercal cyst through a suboccipital burrhole. CONCLUSIONS: The clinical scenario presented here has not been described previously. Endoscopic cyst removal in such a situation is an effective and low-risk procedure that obviates the further need for antihelminthic medications.
[Mh] Termos MeSH primário: Cistos Ósseos/cirurgia
Infecções Parasitárias do Sistema Nervoso Central/cirurgia
Cisterna Magna/cirurgia
Neurocisticercose/cirurgia
[Mh] Termos MeSH secundário: Animais
Cistos Ósseos/patologia
Infecções Parasitárias do Sistema Nervoso Central/patologia
Criança
Constrição Patológica/patologia
Constrição Patológica/cirurgia
Seres Humanos
Masculino
Neuroendoscopia/métodos
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170925
[Lr] Data última revisão:
170925
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170425
[St] Status:MEDLINE


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[PMID]:26924710
[Au] Autor:Hunt NH; Too LK; Khaw LT; Guo J; Hee L; Mitchell AJ; Grau GE; Ball HJ
[Ad] Endereço:Discipline of Pathology, School of Medical Sciences, University of Sydney, NSW 2006, Australia. Electronic address: Nicholas.hunt@sydney.edu.au.
[Ti] Título:The kynurenine pathway and parasitic infections that affect CNS function.
[So] Source:Neuropharmacology;112(Pt B):389-398, 2017 Jan.
[Is] ISSN:1873-7064
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:The kynurenine pathway of tryptophan metabolism has been implicated in brain function, immunoregulation, anti-microbial mechanisms and pregnancy. Some of these actions are due to depletion of tryptophan and others to the formation of biologically active metabolites. This review focuses on the roles of the kynurenine pathway in host responses during two parasitic diseases of major health and economic importance, malaria and toxoplasmosis, with an emphasis on their impacts on CNS function. This article is part of the Special Issue entitled 'The Kynurenine Pathway in Health and Disease'.
[Mh] Termos MeSH primário: Infecções Parasitárias do Sistema Nervoso Central/metabolismo
Cinurenina/metabolismo
Redes e Vias Metabólicas
[Mh] Termos MeSH secundário: Animais
Seres Humanos
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Nm] Nome de substância:
343-65-7 (Kynurenine)
[Em] Mês de entrada:1706
[Cu] Atualização por classe:170605
[Lr] Data última revisão:
170605
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160301
[St] Status:MEDLINE


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[PMID]:27801381
[Au] Autor:Evangelisti MA; Varcasia A; Deiana R; Zobba R; Sanna Passino E; Scala A; Melosu V; Pipia AP; Tamponi C; Manunta ML
[Ad] Endereço:University of Sassari, Sassari, Italy. labparax@uniss.it.
[Ti] Título:Clinical evolution of cerebral coenurosis from invasive to chronic infection in sheep and a goat.
[So] Source:J Infect Dev Ctries;10(10):1151-1155, 2016 Oct 31.
[Is] ISSN:1972-2680
[Cp] País de publicação:Italy
[La] Idioma:eng
[Ab] Resumo:This survey describes the evolution in vivo of Coenurus cerebralis in small ruminants. At presentation, neurological signs and cerebrospinal fluid (CSF) features were suggestive of multifocal or diffuse inflammatory reaction. Magnetic resonance imaging (MRI) captured the transition between the invasive and quiescent phase of the infection, revealing the concurrent presence of meningitis and small cysts. During the quiescent phase, in all animals, neurological symptoms disappeared, and cerebrospinal fluid was unremarkable while cysts grew progressively. Subsequently, the onset of neurological symptoms coincided with MRI signs of diffuse or localized increase of intracranial pressure, as confirmed by direct intracranial pressure measuring. All the animals had an excellent post-surgical recovery. This is the first report describing the evolution of coenurosis in vivo. Sequential imaging allowed describing interesting such as the death of some coenuri and different parasite growth rate in the same host.
[Mh] Termos MeSH primário: Infecções Parasitárias do Sistema Nervoso Central/veterinária
Infecções por Cestoides/patologia
Doenças das Cabras/patologia
Doenças dos Ovinos/patologia
[Mh] Termos MeSH secundário: Animais
Infecções Parasitárias do Sistema Nervoso Central/diagnóstico por imagem
Infecções Parasitárias do Sistema Nervoso Central/patologia
Infecções Parasitárias do Sistema Nervoso Central/cirurgia
Líquido Cefalorraquidiano/citologia
Infecções por Cestoides/diagnóstico por imagem
Infecções por Cestoides/cirurgia
Doenças das Cabras/diagnóstico por imagem
Doenças das Cabras/cirurgia
Cabras
Imagem por Ressonância Magnética
Masculino
Ovinos
Doenças dos Ovinos/diagnóstico por imagem
Doenças dos Ovinos/cirurgia
Procedimentos Cirúrgicos Operatórios
Resultado do Tratamento
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Em] Mês de entrada:1701
[Cu] Atualização por classe:170131
[Lr] Data última revisão:
170131
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161102
[St] Status:MEDLINE
[do] DOI:10.3855/jidc.8719


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[PMID]:27363042
[Au] Autor:El-Bahnasawy MM; El Feky MR; Morsy AT; Ismail MA; Morsy TA
[Ti] Título:EGYPTIAN EOSINOPHILIC AND INFECTIOUS MENINGOENCEPHA- LITIS AND THEIR IMPACT ON PSYCHOLOGICAL ASPECTS.
[So] Source:J Egypt Soc Parasitol;46(1):67-80, 2016 Apr.
[Is] ISSN:1110-0583
[Cp] País de publicação:Egypt
[La] Idioma:eng
[Ab] Resumo:Meningoencephalitis is an acute inflammation of the brain and spinal cord & their covering protective membranes. Meningitis can be life-threatening because of the inflammation's proximity to the brain and spinal cord; therefore, the condition is classified as a medical emergency. The commonest symptoms of meningitis are headache and neck stiffness associated with fever, confusion or altered consciousness, vomiting, and an inability to tolerate light (photophobia) or loud noises (phonophobia). Children often exhibit only nonspecific symptoms, such as irritability and drowsiness. If a rash is present, it may indicate a particular cause of meningitis; for instance, meningitis caused by meningococcal bacteria may be accompanied by a characteristic rash. A broad variety of allergic, infectious, neoplastic, and idiopathic diseases are associated with increased blood and/or tissue eosinophilia and range in severity from self-limited conditions to life-threatening disorders. Although accepted upper limits of normal blood eosinophil numbers vary somewhat, a value above 600 eosinophils /microL of blood is abnormal in the vast majority of cases. Generally speaking, there are several possible causes of eosinophils in the CSF; undoubtedly parasitic infection is one of the main causes.
[Mh] Termos MeSH primário: Infecções Parasitárias do Sistema Nervoso Central/parasitologia
Eosinofilia/líquido cefalorraquidiano
Meningoencefalite/epidemiologia
Meningoencefalite/psicologia
[Mh] Termos MeSH secundário: Infecções Parasitárias do Sistema Nervoso Central/patologia
Infecções Parasitárias do Sistema Nervoso Central/psicologia
Egito/epidemiologia
Seres Humanos
Meningoencefalite/patologia
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Em] Mês de entrada:1608
[Cu] Atualização por classe:160701
[Lr] Data última revisão:
160701
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160702
[St] Status:MEDLINE


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[PMID]:27198802
[Au] Autor:Perry A; Dangoudoubiyam S; Bolling M; Rodrigues-Hoffmann A
[Ad] Endereço:Department of Veterinary Pathobiology, College of Veterinary Medicine and Biomedical Sciences, Texas A&M University, College Station, TX 77843, USA. Electronic address: aperry@cvm.tamu.edu.
[Ti] Título:Aberrant Ancylostoma sp. in the brain of a dog.
[So] Source:Vet Parasitol;223:210-3, 2016 Jun 15.
[Is] ISSN:1873-2550
[Cp] País de publicação:Netherlands
[La] Idioma:eng
[Ab] Resumo:A 14-month-old, male American Bulldog presented to Texas A&M University Veterinary Medical Teaching Hospital in August of 2012 for anorexia, hydrophobia and gradually worsening neurologic signs. Grossly hemorrhage on the left side of the caudal cerebrum and cerebellum was observed and histologically corresponded with necrohemorrhagic and lymphoplasmacytic encephalitis associated with adult nematodes. Based on morphology and molecular analysis, these were identified as Ancylostoma sp.
[Mh] Termos MeSH primário: Ancylostoma/isolamento & purificação
Ancilostomíase/veterinária
Infecções Parasitárias do Sistema Nervoso Central/veterinária
Doenças do Cão/parasitologia
[Mh] Termos MeSH secundário: Ancilostomíase/parasitologia
Ancilostomíase/patologia
Animais
Infecções Parasitárias do Sistema Nervoso Central/parasitologia
Infecções Parasitárias do Sistema Nervoso Central/patologia
Doenças do Cão/patologia
Cães
Masculino
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Em] Mês de entrada:1704
[Cu] Atualização por classe:170421
[Lr] Data última revisão:
170421
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160521
[St] Status:MEDLINE


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[PMID]:26894629
[Au] Autor:Carpio A; Romo ML; Parkhouse RM; Short B; Dua T
[Ad] Endereço:a Escuela de Medicina , Universidad de Cuenca , Cuenca , Ecuador.
[Ti] Título:Parasitic diseases of the central nervous system: lessons for clinicians and policy makers.
[So] Source:Expert Rev Neurother;16(4):401-14, 2016.
[Is] ISSN:1744-8360
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Parasitic diseases of the central nervous system are associated with high mortality and morbidity, especially in resource-limited settings. The burden of these diseases is amplified as survivors are often left with neurologic sequelae affecting mobility, sensory organs, and cognitive functions, as well as seizures/epilepsy. These diseases inflict suffering by causing lifelong disabilities, reducing economic productivity, and causing social stigma. The complexity of parasitic life cycles and geographic specificities, as well as overlapping clinical manifestations in the host reflecting the diverse pathogenesis of parasites, can present diagnostic challenges. We herein provide an overview of these parasitic diseases and summarize clinical aspects, diagnosis, therapeutic strategies and recent milestones, and aspects related to prevention and control.
[Mh] Termos MeSH primário: Pessoal Administrativo
Infecções Parasitárias do Sistema Nervoso Central/diagnóstico
Infecções Parasitárias do Sistema Nervoso Central/terapia
Gerenciamento Clínico
[Mh] Termos MeSH secundário: Pessoal Administrativo/psicologia
Antiparasitários
Infecções Parasitárias do Sistema Nervoso Central/complicações
Infecções Parasitárias do Sistema Nervoso Central/epidemiologia
Seres Humanos
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Nm] Nome de substância:
0 (Antiparasitic Agents)
[Em] Mês de entrada:1612
[Cu] Atualização por classe:170220
[Lr] Data última revisão:
170220
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160220
[St] Status:MEDLINE
[do] DOI:10.1586/14737175.2016.1155454


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[PMID]:26376794
[Au] Autor:Moazeni M; Oryan A; Sharifiyazdi H; Amrabadi O; Akbari M
[Ad] Endereço:Department of Parasitology,School of Veterinary Medicine, Shiraz University,Shiraz,Iran.
[Ti] Título:A rare case of cerebral hydatidosis caused by a G1 genotype of Echinococcus granulosus in a cow from Iran.
[So] Source:J Helminthol;90(5):634-7, 2016 Sep.
[Is] ISSN:1475-2697
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Hydatidosis is a medically and veterinary important parasitic disease that is endemic in many parts of the world. Unilocular hydatid cysts may develop in almost any part of the body. Up to 70% of hydatid cysts are located in the liver, followed by 25% in the lungs. Cerebral hydatidosis is an uncommon manifestation of the disease, occurring in less than 1/1000 infected hosts, yet diagnosis does pose a problem. We have reported an exceptionally rare case of cerebral hydatidosis in cattle. This is the first report to describe the characteristic pathological features of the cerebral hydatidosis in cattle caused by the G1 genotype of Echinococcus granulosus. Genotypic analysis was performed on a hydatid cyst from a cow originating from southern Iran, based on the sequence analysis of the cox1 mitochondrial gene.
[Mh] Termos MeSH primário: Doenças dos Bovinos/diagnóstico
Doenças dos Bovinos/patologia
Infecções Parasitárias do Sistema Nervoso Central/veterinária
Equinococose/veterinária
Echinococcus granulosus/classificação
Echinococcus granulosus/genética
Genótipo
[Mh] Termos MeSH secundário: Animais
Bovinos
Doenças dos Bovinos/parasitologia
Infecções Parasitárias do Sistema Nervoso Central/diagnóstico
Infecções Parasitárias do Sistema Nervoso Central/parasitologia
Infecções Parasitárias do Sistema Nervoso Central/patologia
Equinococose/diagnóstico
Equinococose/parasitologia
Equinococose/patologia
Echinococcus granulosus/isolamento & purificação
Técnicas de Genotipagem
Irã (Geográfico)
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1702
[Cu] Atualização por classe:170227
[Lr] Data última revisão:
170227
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:150918
[St] Status:MEDLINE
[do] DOI:10.1017/S0022149X1500084X


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[PMID]:26065933
[Au] Autor:Shih RY; Koeller KK
[Ad] Endereço:From the Department of Neuroradiology, American Institute for Radiologic Pathology, 1010 Wayne Ave, Suite 320, Silver Spring, MD 20910 (R.Y.S., K.K.K.); Department of Radiology, Walter Reed National Military Medical Center, Bethesda, Md (R.Y.S.); and Department of Radiology, Mayo Clinic, Rochester, Minn (K.K.K.).
[Ti] Título:Bacterial, Fungal, and Parasitic Infections of the Central Nervous System: Radiologic-Pathologic Correlation and Historical Perspectives.
[So] Source:Radiographics;35(4):1141-69, 2015 Jul-Aug.
[Is] ISSN:1527-1323
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Despite remarkable progress in prevention and treatment, infectious diseases affecting the central nervous system remain an important source of morbidity and mortality, particularly in less-developed countries and in immunocompromised persons. Bacterial, fungal, and parasitic pathogens are derived from living organisms and affect the brain, spinal cord, or meninges. Infections due to these pathogens are associated with a variety of neuroimaging patterns that can be appreciated at magnetic resonance imaging in most cases. Bacterial infections, most often due to Streptococcus, Haemophilus, and Neisseria species, cause significant meningitis, whereas the less common cerebritis and subsequent abscess formation have well-documented progression, with increasingly prominent altered signal intensity and corresponding contrast enhancement. Atypical bacterial infections are characterized by the development of a granulomatous response, classically seen in tuberculosis, in which the tuberculoma is the most common parenchymal form of the disease; spirochetal and rickettsial diseases are less common. Fungal infections predominate in immunocompromised hosts and are caused by yeasts, molds, and dimorphic fungi. Cryptococcal meningitis is the most common fungal infection, whereas candidiasis is the most common nosocomial infection. Mucormycosis and aspergillosis are characterized by angioinvasiveness and are associated with high morbidity and mortality among immunocompromised patients. In terms of potential exposure in the worldwide population, parasitic infections, including neurocysticercosis, toxoplasmosis, echinococcosis, malaria, and schistosomiasis, are the greatest threat. Rare amebic infections are noteworthy for their extreme virulence and high mortality. The objective of this article is to highlight the characteristic neuroimaging manifestations of bacterial, fungal, and parasitic diseases, with emphasis on radiologic-pathologic correlation and historical perspectives.
[Mh] Termos MeSH primário: Infecções Bacterianas do Sistema Nervoso Central/história
Infecções Fúngicas do Sistema Nervoso Central/história
Infecções Parasitárias do Sistema Nervoso Central/história
Encefalite Infecciosa/história
Imagem por Ressonância Magnética/história
[Mh] Termos MeSH secundário: Infecções Bacterianas do Sistema Nervoso Central/patologia
Infecções Fúngicas do Sistema Nervoso Central/patologia
Infecções Parasitárias do Sistema Nervoso Central/patologia
História do Século XIX
História do Século XX
História do Século XXI
Seres Humanos
[Pt] Tipo de publicação:HISTORICAL ARTICLE; JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T; RESEARCH SUPPORT, U.S. GOV'T, NON-P.H.S.
[Em] Mês de entrada:1604
[Cu] Atualização por classe:150716
[Lr] Data última revisão:
150716
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:150613
[St] Status:MEDLINE
[do] DOI:10.1148/rg.2015140317


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[PMID]:25687750
[Au] Autor:Thanaviratananich S; Thanaviratananich S; Ngamjarus C
[Ad] Endereço:Neurological Institute, University Hospitals Case Medical Center, Cleveland, Ohio, USA.
[Ti] Título:Corticosteroids for parasitic eosinophilic meningitis.
[So] Source:Cochrane Database Syst Rev;(2):CD009088, 2015 Feb 17.
[Is] ISSN:1469-493X
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Angiostrongylus cantonensis (A. cantonensis) is the major cause of infectious eosinophilic meningitis. Dead larvae of this parasite cause inflammation and exacerbate symptoms of meningitis. Corticosteroids are drugs used to reduce the inflammation caused by this parasite. OBJECTIVES: To assess the efficacy and safety of corticosteroids for the treatment of eosinophilic meningitis. SEARCH METHODS: We searched CENTRAL (2014, Issue 11), MEDLINE (1950 to November Week 3, 2014), EMBASE (1974 to December 2014), Scopus (1960 to December 2014), Web of Science (1955 to December 2014), LILACS (1982 to December 2014) and CINAHL (1981 to December 2014). SELECTION CRITERIA: Randomised controlled trials (RCTs) of corticosteroids versus placebo for eosinophilic meningitis. DATA COLLECTION AND ANALYSIS: Two review authors (SiT, SaT) independently collected and extracted study data. We graded the methodological quality of the RCTs. We identified and analysed outcomes and adverse effects. MAIN RESULTS: We did not identifiy any new trials for inclusion or exclusion in this 2014 update. One study involving 110 participants (55 participants in each group) met our inclusion criteria. The corticosteroid (prednisolone) showed a benefit in shortening the median time to resolution of headaches (five days in the treatment group versus 13 days in the control group, P value < 0.0001). Corticosteroids were also associated with smaller numbers of participants who still had headaches after a two-week course of treatment (9.1% versus 45.5%, P value < 0.0001). The number of patients who needed repeat lumbar puncture was also smaller in the treatment group (12.7% versus 40%, P value = 0.002). There was a reduction in the median time of analgesic use in participants receiving corticosteroids (10.5 versus 25.0, P value = 0.038). There were no reported adverse effects from prednisolone in the treatment group. AUTHORS' CONCLUSIONS: Corticosteroids significantly help relieve headache in patients with eosinophilic meningitis, who have a pain score of four or more on a visual analogue scale. However, there is only one RCT supporting this benefit and this trial did not clearly mention allocation concealment and stratification. Therefore, we agreed to grade our included study as a moderate quality trial. Future well-designed RCTs are necessary.
[Mh] Termos MeSH primário: Infecções Parasitárias do Sistema Nervoso Central/tratamento farmacológico
Eosinofilia/tratamento farmacológico
Glucocorticoides/uso terapêutico
Meningite/tratamento farmacológico
Prednisolona/uso terapêutico
[Mh] Termos MeSH secundário: Animais
Seres Humanos
Ensaios Clínicos Controlados Aleatórios como Assunto
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T; REVIEW
[Nm] Nome de substância:
0 (Glucocorticoids); 9PHQ9Y1OLM (Prednisolone)
[Em] Mês de entrada:1506
[Cu] Atualização por classe:160602
[Lr] Data última revisão:
160602
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:150218
[St] Status:MEDLINE
[do] DOI:10.1002/14651858.CD009088.pub3



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BIREME/OPAS/OMS - Centro Latino-Americano e do Caribe de Informação em Ciências da Saúde