Base de dados : MEDLINE
Pesquisa : C03.858.211.480.708 [Categoria DeCS]
Referências encontradas : 2856 [refinar]
Mostrando: 1 .. 10   no formato [Detalhado]

página 1 de 286 ir para página                         

  1 / 2856 MEDLINE  
              next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:29183283
[Au] Autor:Fraser TA; Shao R; Fountain-Jones NM; Charleston M; Martin A; Whiteley P; Holme R; Carver S; Polkinghorne A
[Ad] Endereço:School of Biological Sciences, University of Tasmania, Sandy Bay, Hobart, TAS, Australia.
[Ti] Título:Mitochondrial genome sequencing reveals potential origins of the scabies mite Sarcoptes scabiei infesting two iconic Australian marsupials.
[So] Source:BMC Evol Biol;17(1):233, 2017 Nov 28.
[Is] ISSN:1471-2148
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Debilitating skin infestations caused by the mite, Sarcoptes scabiei, have a profound impact on human and animal health globally. In Australia, this impact is evident across different segments of Australian society, with a growing recognition that it can contribute to rapid declines of native Australian marsupials. Cross-host transmission has been suggested to play a significant role in the epidemiology and origin of mite infestations in different species but a chronic lack of genetic resources has made further inferences difficult. To investigate the origins and molecular epidemiology of S. scabiei in Australian wildlife, we sequenced the mitochondrial genomes of S. scabiei from diseased wombats (Vombatus ursinus) and koalas (Phascolarctos cinereus) spanning New South Wales, Victoria and Tasmania, and compared them with the recently sequenced mitochondrial genome sequences of S. scabiei from humans. RESULTS: We found unique S. scabiei haplotypes among individual wombat and koala hosts with high sequence similarity (99.1% - 100%). Phylogenetic analysis of near full-length mitochondrial genomes revealed three clades of S. scabiei (one human and two marsupial), with no apparent geographic or host species pattern, suggestive of multiple introductions. The availability of additional mitochondrial gene sequences also enabled a re-evaluation of a range of putative molecular markers of S. scabiei, revealing that cox1 is the most informative gene for molecular epidemiological investigations. Utilising this gene target, we provide additional evidence to support cross-host transmission between different animal hosts. CONCLUSIONS: Our results suggest a history of parasite invasion through colonisation of Australia from hosts across the globe and the potential for cross-host transmission being a common feature of the epidemiology of this neglected pathogen. If this is the case, comparable patterns may exist elsewhere in the 'New World'. This work provides a basis for expanded molecular studies into mange epidemiology in humans and animals in Australia and other geographic regions.
[Mh] Termos MeSH primário: Genoma Mitocondrial
Marsupiais/parasitologia
Sarcoptes scabiei/genética
Escabiose/parasitologia
Análise de Sequência de DNA
[Mh] Termos MeSH secundário: Animais
Animais Selvagens/genética
Austrália/epidemiologia
Composição de Bases/genética
Sequência de Bases
Complexo IV da Cadeia de Transporte de Elétrons/genética
Genes Mitocondriais
Tamanho do Genoma
Haplótipos/genética
Seres Humanos
Anotação de Sequência Molecular
Filogenia
Escabiose/epidemiologia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
EC 1.9.3.1 (Electron Transport Complex IV)
[Em] Mês de entrada:1803
[Cu] Atualização por classe:180309
[Lr] Data última revisão:
180309
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171130
[St] Status:MEDLINE
[do] DOI:10.1186/s12862-017-1086-9


  2 / 2856 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
[PMID]:29292916
[Au] Autor:Jonsson P; Lindelöf B; Nordlind K; Bornstein S
[Ad] Endereço:Karolinska Universitetssjukhuset - Hudkliniken Stockholm, Sweden Karolinska Universitetssjukhuset - Hudkliniken Stockholm, Sweden.
[Ti] Título:Vid klåda, tänk alltid på skabb!.
[So] Source:Lakartidningen;114, 2017 Nov 07.
[Is] ISSN:1652-7518
[Cp] País de publicação:Sweden
[La] Idioma:swe
[Ab] Resumo:In case of pruritus, always consider scabies! Scabies is an itching skin disease caused by the mite Sarcoptes scabiei which affects more than 100 million people worldwide. Regarded as a neglected tropical disease by the WHO, it is a major public health burden in endemic areas. As direct skin-to-skin contact is the main route of transmission family members and sexual partners are often affected. Typical presentation includes a severely pruritic rash with predilection for the extremities and the trunk. Definitive diagnosis relies on microscopic identification of the mites. Future, more efficient, diagnostic methods may include serological testing or PCR for S. scabiei DNA. A benzyl benzoate and disulfiram based lotion, Tenutex, is the treatment of choice in Sweden with topical permethrin or oral ivermectin being used in certain cases. Scabies is an important diagnosis to consider in all patients presenting with pruritus.
[Mh] Termos MeSH primário: Escabiose
[Mh] Termos MeSH secundário: Idoso
Animais
Antiparasitários/administração & dosagem
Antiparasitários/uso terapêutico
Criança
Seres Humanos
Lactente
Prurido/parasitologia
Sarcoptes scabiei
Escabiose/diagnóstico
Escabiose/tratamento farmacológico
Escabiose/epidemiologia
Escabiose/patologia
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Nm] Nome de substância:
0 (Antiparasitic Agents)
[Em] Mês de entrada:1803
[Cu] Atualização por classe:180306
[Lr] Data última revisão:
180306
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180103
[St] Status:MEDLINE


  3 / 2856 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo SciELO Brasil
[PMID]:29186253
[Au] Autor:Lima FCDR; Cerqueira AMM; Guimarães MBS; Padilha CBS; Craide FH; Bombardelli M
[Ad] Endereço:Dermatology Service of the General Polyclinic of Rio de Janeiro (PGRJ) - Rio de Janeiro (RJ), Brazil.
[Ti] Título:Crusted scabies due to indiscriminate use of glucocorticoid therapy in infant.
[So] Source:An Bras Dermatol;92(3):383-385, 2017 May-Jun.
[Is] ISSN:1806-4841
[Cp] País de publicação:Brazil
[La] Idioma:eng
[Ab] Resumo:Crusted or Norwegian scabies is a parasitic infectious disease caused by Sarcoptes scabiei var. hominis that mainly affects immunocompromised individuals and those with neurological patients. We report a case of crusted scabies in a 4-month-old infant who had been treated erroneously for atopic dermatitis with high doses of corticosteroids. This initial misdiagnosis associated with the abusive use of corticosteroid facilitated the evolution of scabies to crusted scabies and its main complications of secondary infection and sepsis.
[Mh] Termos MeSH primário: Glucocorticoides/efeitos adversos
Permetrina/uso terapêutico
Escabiose/diagnóstico
Escabiose/tratamento farmacológico
Sepse/etiologia
[Mh] Termos MeSH secundário: Adolescente
Erros de Diagnóstico
Evolução Fatal
Seres Humanos
Hospedeiro Imunocomprometido
Lactente
Masculino
Escabiose/complicações
[Pt] Tipo de publicação:CASE REPORTS
[Nm] Nome de substância:
0 (Glucocorticoids); 509F88P9SZ (Permethrin)
[Em] Mês de entrada:1801
[Cu] Atualização por classe:180131
[Lr] Data última revisão:
180131
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171130
[St] Status:MEDLINE


  4 / 2856 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:29190303
[Au] Autor:Khalil S; Abbas O; Kibbi AG; Kurban M
[Ad] Endereço:Department of Dermatology, American University of Beirut, Beirut, Lebanon.
[Ti] Título:Scabies in the age of increasing drug resistance.
[So] Source:PLoS Negl Trop Dis;11(11):e0005920, 2017 Nov.
[Is] ISSN:1935-2735
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Scabies is an infestation of the skin by the mite Sarcoptes scabiei. It manifests with pruritic erythematous papules and excoriations, in addition to the pathognomonic burrows. Multiple drugs can be used for treatment, but resistance to conventional therapy is increasing throughout the years. This paper will review the mechanisms of resistance proposed in the literature and some of the potential solutions to this problem.
[Mh] Termos MeSH primário: Resistência a Inseticidas
Sarcoptes scabiei/efeitos dos fármacos
Escabiose/tratamento farmacológico
[Mh] Termos MeSH secundário: Transportadores de Cassetes de Ligação de ATP/metabolismo
Animais
Seres Humanos
Inseticidas/uso terapêutico
Escabiose/complicações
Escabiose/parasitologia
Pele/parasitologia
Canais de Sódio/metabolismo
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Nm] Nome de substância:
0 (ATP-Binding Cassette Transporters); 0 (Insecticides); 0 (Sodium Channels)
[Em] Mês de entrada:1712
[Cu] Atualização por classe:171219
[Lr] Data última revisão:
171219
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171201
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pntd.0005920


  5 / 2856 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo SciELO Brasil
[PMID]:28954112
[Au] Autor:Bu X; Fan J; Hu X; Bi X; Peng B; Zhang D
[Ad] Endereço:Department of Dermatology at Shanghai Gongli Hospital - Second Military Medical University - Shanghai, China.
[Ti] Título:Norwegian scabies in a patient treated with Tripterygium glycoside for rheumatoid arthritis.
[So] Source:An Bras Dermatol;92(4):556-558, 2017 Jul-Aug.
[Is] ISSN:1806-4841
[Cp] País de publicação:Brazil
[La] Idioma:eng
[Ab] Resumo:We report an 80-year-old male patient with severe rheumatoid arthritis who was treated with tripterygium glycoside, an immunosuppressive agent made from the extract of a Chinese medicinal herb called Tripterygium wilfordii Hook F. The patient had no apparent skin lesions before the treatment, but he developed aggressive hyperkeratotic lesions with rapid progression after using tripterygium glycoside. He was repeatedly diagnosed with eczema, but treatment failed to achieve efficacy. Interestingly, a microscopic examination of the lesions revealed numerous scabies mites and eggs. Thus, we confirmed the diagnosis of Norwegian scabies infection. Treated with crotamiton 10% cream and 10% sulfur ointment for one month, the patient's clinical symptoms disappeared.
[Mh] Termos MeSH primário: Artrite Reumatoide/tratamento farmacológico
Glicosídeos/efeitos adversos
Escabiose/induzido quimicamente
Tripterygium/química
[Mh] Termos MeSH secundário: Idoso de 80 Anos ou mais
Animais
Seres Humanos
Masculino
Extratos Vegetais/efeitos adversos
Sarcoptes scabiei
Escabiose/diagnóstico
[Pt] Tipo de publicação:CASE REPORTS
[Nm] Nome de substância:
0 (Glycosides); 0 (Plant Extracts)
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171010
[Lr] Data última revisão:
171010
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170928
[St] Status:MEDLINE


  6 / 2856 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
[PMID]:28783773
[Au] Autor:Campbell JJ; Paulson CP; Nashelsky J
[Ad] Endereço:United States Air Force Eglin Family Medicine Residency, FL, USA.
[Ti] Título:Clinical Inquiry: What is the most effective treatment for scabies?
[So] Source:J Fam Pract;66(8):E11-E12, 2017 Aug.
[Is] ISSN:1533-7294
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:EVIDENCE-BASED ANSWER: Topical permethrin is the most effective treatment for classic scabies (strength of recommendation [SOR]: A, meta-analyses with consistent results). Topical lindane and crotamiton are inferior to permethrin but appear equivalent to each other and benzyl benzoate, sulfur, and natural synergized pyrethrins (SOR: B, limited randomized trials). Although not as effective as topical permethrin, oral ivermectin is an effective treatment compared with placebo (SOR: B, a single small randomized trial). Oral ivermectin may reduce the prevalence of scabies at one year in populations with endemic disease more than topical permethrin (SOR: B, a single randomized trial).
[Mh] Termos MeSH primário: Antiparasitários/uso terapêutico
Benzoatos/uso terapêutico
Inseticidas/uso terapêutico
Lindano/uso terapêutico
Escabiose/tratamento farmacológico
[Mh] Termos MeSH secundário: Administração Oral
Administração Tópica
Animais
Seres Humanos
Sarcoptes scabiei/efeitos dos fármacos
Enxofre/uso terapêutico
Toluidinas/uso terapêutico
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Antiparasitic Agents); 0 (Benzoates); 0 (Insecticides); 0 (Toluidines); 59NEE7PCAB (Lindane); 70FD1KFU70 (Sulfur); N863NB338G (benzyl benzoate)
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170904
[Lr] Data última revisão:
170904
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:170808
[St] Status:MEDLINE


  7 / 2856 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:28771469
[Au] Autor:Walker SL; Lebas E; De Sario V; Deyasso Z; Doni SN; Marks M; Roberts CH; Lambert SM
[Ad] Endereço:London School of Hygiene and Tropical Medicine, London, United Kingdom.
[Ti] Título:The prevalence and association with health-related quality of life of tungiasis and scabies in schoolchildren in southern Ethiopia.
[So] Source:PLoS Negl Trop Dis;11(8):e0005808, 2017 Aug.
[Is] ISSN:1935-2735
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: The prevalence of skin disease in low and middle income countries is high and communicable skin diseases are a significant public health problem. Tungiasis is an ectoparasite infestation caused by the flea Tunga penetrans, which has a widespread geographical distribution. Tungiasis causes painful skin lesions and may affect activities of daily living. OBJECTIVE: We wished to determine the prevalence and impact of tungiasis and scabies in schoolchildren in southern Ethiopia. METHODS: A cross-sectional study was performed in which students were examined by dermatologists and the skin disorders recorded. Individuals with pyogenic skin infections, scabies and tungiasis were also invited to complete the Children's Dermatology Life Quality Index. RESULTS: There was a high burden of skin disease amongst this cohort with more than 40% having an ectodermal parasitic skin disease. The majority of these were due to tungiasis. Tungiasis was evident in more than a third of children and was associated with onychodystophy. There was a significant association between wearing "closed" footwear and a greater number of tungiasis lesions but not tungiasis per se. Dermatophyte infections, acne and plantar maceration secondary to occlusive footwear were also common. Scabies and tungiasis appeared to have a significant negative effect on quality of life. CONCLUSION: Tungiasis is highly prevalent in schoolchildren in the part of Ethiopia where the study was conducted and is associated with a deleterious effect on quality of life. The role of footwear in both preventing and possibly exacerbating cutaneous ailments in this setting requires further study.
[Mh] Termos MeSH primário: Qualidade de Vida
Escabiose/epidemiologia
Tungíase/epidemiologia
[Mh] Termos MeSH secundário: Atividades Cotidianas
Adolescente
Animais
Criança
Efeitos Psicossociais da Doença
Estudos Transversais
Etiópia/epidemiologia
Feminino
Seres Humanos
Masculino
Saúde Pública
Sarcoptes scabiei
Instituições Acadêmicas
Sapatos
Tunga
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1708
[Cu] Atualização por classe:171025
[Lr] Data última revisão:
171025
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170804
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pntd.0005808


  8 / 2856 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:28767353
[Au] Autor:Elosua-González M; García-Zamora E
[Ad] Endereço:Hospital Universitario Fundación Alcorcón, Alcorcon, Spain mgonzaleze@fhalcorcon.es.
[Ti] Título:Crusted Scabies.
[So] Source:N Engl J Med;377(5):476, 2017 Aug 03.
[Is] ISSN:1533-4406
[Cp] País de publicação:United States
[La] Idioma:eng
[Mh] Termos MeSH primário: Sarcoptes scabiei
Escabiose/patologia
Pele/patologia
[Mh] Termos MeSH secundário: Idoso
Animais
Erros de Diagnóstico
Seres Humanos
Masculino
Escabiose/diagnóstico
Pele/parasitologia
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Em] Mês de entrada:1708
[Cu] Atualização por classe:170808
[Lr] Data última revisão:
170808
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:170803
[St] Status:MEDLINE
[do] DOI:10.1056/NEJMicm1616169


  9 / 2856 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:28722633
[Au] Autor:Naz S; Desclozeaux M; Mounsey KE; Chaudhry FR; Walton SF
[Ad] Endereço:Department of Zoology, Faculty of Sciences, Pir Mehr Ali Shah Arid Agriculture University Rawalpindi, Rawalpindi, Pakistan.
[Ti] Título:Characterization of Tropomyosin and Paramyosin: Immunoreactive Allergens in Scabies.
[So] Source:Am J Trop Med Hyg;97(3):851-860, 2017 Sep.
[Is] ISSN:1476-1645
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Scabies is a human skin disease due to the burrowing ectoparasite var. resulting in intense itching and inflammation and manifesting as a skin allergy. Because of insufficient mite material and lack of in vitro propagation system for antigen preparation, scabies is a challenging disease to develop serological diagnostics. For allergen characterization, full-length tropomyosin (Sar s 10) was cloned, expressed in pET-15b, and assessed for reactivity with IgE antibodies from human sera. IgE binding was observed to Sar s 10 with sera collected from subjects with ordinary scabies, house dust mite (HDM)-positive and naive subjects and a diagnostic sensitivity of < 30% was observed. paramyosin (Sar s 11) was cloned, and expressed in pET-28a in three overlapping fragments designated Sspara1, Sspara2, and Sspara3. IgE and IgG binding was observed to Sspara2 and Sspara3 antigens with sera collected from ordinary scabies, and HDM-positive subjects, but no binding was observed with sera collected from naive subjects. Sspara2 displayed excellent diagnostic potential with 98% sensitivity and 90% specificity observed for IgE binding and 70% sensitivity for IgG. In contrast, the diagnostic sensitivity of Sspara3 was 84% for IgE binding and 40% for IgG binding. In combination, Sspara2 and Sspara3 provided an IgE sensitivity of 94%. This study shows that IgE binding to Sspara2 and Sspara3 is a highly sensitive method for diagnosis of scabies infestation in clinical practice. The developed enzyme-linked immunosorbent assay helps direct future development of a specific diagnostic tool for scabies.
[Mh] Termos MeSH primário: Alérgenos/metabolismo
Sarcoptes scabiei/metabolismo
Escabiose/parasitologia
Tropomiosina/metabolismo
[Mh] Termos MeSH secundário: Animais
Clonagem Molecular
DNA Complementar/genética
Regulação da Expressão Gênica/fisiologia
Imunoglobulina G/imunologia
Filogenia
Ligação Proteica
Sarcoptes scabiei/genética
Tropomiosina/genética
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Allergens); 0 (DNA, Complementary); 0 (Immunoglobulin G); 0 (Tropomyosin)
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171018
[Lr] Data última revisão:
171018
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:170720
[St] Status:MEDLINE
[do] DOI:10.4269/ajtmh.16-0976


  10 / 2856 MEDLINE  
              first record previous record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:28722612
[Au] Autor:Romani L; Whitfeld MJ; Koroivueta J; Kama M; Wand H; Tikoduadua L; Tuicakau M; Koroi A; Ritova R; Andrews R; Kaldor JM; Steer AC
[Ad] Endereço:Kirby Institute, University of New South Wales, Sydney, Australia.
[Ti] Título:The Epidemiology of Scabies and Impetigo in Relation to Demographic and Residential Characteristics: Baseline Findings from the Skin Health Intervention Fiji Trial.
[So] Source:Am J Trop Med Hyg;97(3):845-850, 2017 Sep.
[Is] ISSN:1476-1645
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Scabies and associated impetigo are under-recognized causes of morbidity in many developing countries. To strengthen the evidence base for scabies control we undertook a trial of mass treatment for scabies. We report on the occurrence and predictors of scabies and impetigo in participants at baseline. Participants were recruited in six island communities and were examined for the presence of scabies and impetigo. In addition to descriptive analyses, logistic regression models were fit to assess the association between demographic variables and outcome of interest. The study enrolled 2051 participants. Scabies prevalence was 36.4% (95% confidence interval [CI] 34.3-38.5), highest in children 5-9 years (55.7%). Impetigo prevalence was 23.4% (95% CI 21.5-25.2) highest in children aged 10-14 (39.0%). People with scabies were 2.8× more likely to have impetigo. The population attributable risk of scabies as a cause of impetigo was 36.3% and 71.0% in children aged less than five years. Households with four or more people sharing the same room were more likely to have scabies and impetigo (odds ratios [OR] 1.6, 95% CI 1.2-2.2 and OR 2.3, 95% CI 1.6-3.2 respectively) compared to households with rooms occupied by a single individual. This study confirms the high burden of scabies and impetigo in Fiji and the association between these two conditions, particularly in young children. Overcrowding, young age, and clinical distribution of lesion are important risk factors for scabies and impetigo. Further studies are needed to investigate whether the decline of endemic scabies would translate into a definite reduction of the burden of associated complications.
[Mh] Termos MeSH primário: Habitação
Impetigo/epidemiologia
Impetigo/prevenção & controle
Escabiose/epidemiologia
Escabiose/prevenção & controle
[Mh] Termos MeSH secundário: Adolescente
Adulto
Criança
Pré-Escolar
Feminino
Fiji/epidemiologia
Seres Humanos
Masculino
Razão de Chances
Prevalência
Fatores de Risco
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171018
[Lr] Data última revisão:
171018
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:170720
[St] Status:MEDLINE
[do] DOI:10.4269/ajtmh.16-0753



página 1 de 286 ir para página                         
   


Refinar a pesquisa
  Base de dados : MEDLINE Formulário avançado   

    Pesquisar no campo  
1  
2
3
 
           



Search engine: iAH v2.6 powered by WWWISIS

BIREME/OPAS/OMS - Centro Latino-Americano e do Caribe de Informação em Ciências da Saúde