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[PMID]:29405683
[Au] Autor:Tsapko NV
[Ti] Título:[Ticks (Acari, ixodidae) of the North Caucasus: Species diversity, host-parasite relationships].
[So] Source:Parazitologiia;51(2):104-20, 2017 Mar-Apr.
[Is] ISSN:0031-1847
[Cp] País de publicação:Russia (Federation)
[La] Idioma:rus
[Ab] Resumo:Biological diversity of ixodid tick fauna of the North Caucasus is analyzed. On the whole, 38 tick species are represented in the fauna of the North Caucasus. Their distribution within the region, biotopic features, and host-parasite relationships of different stages of ontogenesis are considered.
[Mh] Termos MeSH primário: Interações Hospedeiro-Parasita
Ixodidae/fisiologia
Filogenia
Infestações por Carrapato/epidemiologia
Infestações por Carrapato/veterinária
[Mh] Termos MeSH secundário: Animais
Biodiversidade
Aves/classificação
Aves/parasitologia
Carnívoros/classificação
Carnívoros/parasitologia
Ouriços-Cacheiros/classificação
Ouriços-Cacheiros/parasitologia
Especificidade de Hospedeiro
Seres Humanos
Ixodidae/classificação
Lagomorpha/classificação
Lagomorpha/parasitologia
Roedores/classificação
Roedores/parasitologia
Ruminantes/classificação
Ruminantes/parasitologia
Federação Russa/epidemiologia
Especificidade da Espécie
Infestações por Carrapato/parasitologia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180222
[Lr] Data última revisão:
180222
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180207
[St] Status:MEDLINE


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[PMID]:29401575
[Au] Autor:Dokuchaev NE
[Ti] Título:[A case of the tick (Ixodidae) hiperinvasion of the tundra vole in magadan environs].
[So] Source:Parazitologiia;51(1):45-50, 2017 Jan-Feb.
[Is] ISSN:0031-1847
[Cp] País de publicação:Russia (Federation)
[La] Idioma:rus
[Ab] Resumo:A case of tundra vole death as a result its hyperinvasion by ticks Ixodes angustus on the northern periphery of the Asiatic range of the parasite is given.
[Mh] Termos MeSH primário: Arvicolinae/parasitologia
Ixodes/patogenicidade
Infestações por Carrapato/parasitologia
[Mh] Termos MeSH secundário: Animais
Evolução Fatal
Ixodes/fisiologia
Masculino
Sibéria
Infestações por Carrapato/patologia
Tundra
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180222
[Lr] Data última revisão:
180222
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180206
[St] Status:MEDLINE


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[PMID]:28930522
[Au] Autor:Andreotti R; Giachetto PF; Cunha RC
[Ad] Endereço:Laboratorio de Biologia Molecular do Carrapato, Sanidade Animal, Embrapa Gado de Corte, Campo Grande, MS, Brasil, renato.andreotti@embrapa.br.
[Ti] Título:Advances in tick vaccinology in Brazil: from gene expression to immunoprotection.
[So] Source:Front Biosci (Schol Ed);10:127-142, 2018 01 01.
[Is] ISSN:1945-0524
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:has substantial economic impact on the cattle breeding industry and, chemical control and tick resistance development are the major concern. There is a worldwide search for new options, and control using vaccines has been the main focus nowadays. Studies performed in Brazil found that Bm86-based immunization of bovines reduced the infestation of of vaccinated bovines by 45% to 60%. Native tripsin inhibitors (BmTIs) with trypsin-, kallikrein-, and elastase-inhibiting activities have been used as immunogens in bovines reaching 72.8.% of efficacy. The reverse vaccinology approach has also been used for antigen search using transcriptome analysis to identify and characterize potential antigens. Study has generated more than 600 million sequences using RNA-seq of larvae, nymphs, salivary glands, intestines, and ovaries of the tick . Based on the set of transcripts obtained using this strategy, a total of 20,326 protein sequences have been identified. A pipeline analysis built in house identified the protein sequences that were most likely to be immunogenic based on the overall structural characteristic analysis.
[Mh] Termos MeSH primário: Doenças dos Bovinos/prevenção & controle
Doenças dos Bovinos/parasitologia
Rhipicephalus/genética
Rhipicephalus/imunologia
Infestações por Carrapato/veterinária
Vacinas/imunologia
[Mh] Termos MeSH secundário: Animais
Brasil
Bovinos
Expressão Gênica
Infestações por Carrapato/prevenção & controle
Inibidores da Tripsina/imunologia
Vacinação/veterinária
Vacinas/administração & dosagem
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (Trypsin Inhibitors); 0 (Vaccines)
[Em] Mês de entrada:1712
[Cu] Atualização por classe:180122
[Lr] Data última revisão:
180122
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170921
[St] Status:MEDLINE


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[PMID]:29190046
[Au] Autor:Hytönen J; Khawaja T; Grönroos JO; Jalava A; Meri S; Oksi J
[Ti] Título:Relapsing fever.
[So] Source:Duodecim;132(21):1952-6, 2016.
[Is] ISSN:0012-7183
[Cp] País de publicação:Finland
[La] Idioma:eng
[Ab] Resumo:Relapsing fewer is an infection to be considered in the differential diagnosis of an immigrant´s febrile illness. It is a severe, tick-borne or body louse-borne infection caused by the relapsing fever associated borrelia species. The body louse-borne infection is in particular encountered in the Horn of Africa region due to poor hygiene, and has during the past year been described in several European countries as imported by refugees coming from this region. Doctors should thus bear relapsing fever in mind as a differential diagnosis in a febrile refugee having recently arrived in Finland.
[Mh] Termos MeSH primário: Borrelia
Infestações por Piolhos/diagnóstico
Refugiados
Febre Recorrente/diagnóstico
Infestações por Carrapato/diagnóstico
[Mh] Termos MeSH secundário: Animais
Diagnóstico Diferencial
Seres Humanos
Viagem
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Em] Mês de entrada:1801
[Cu] Atualização por classe:180108
[Lr] Data última revisão:
180108
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171201
[St] Status:MEDLINE


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[PMID]:29187953
[Au] Autor:Davari B; Alam FN; Nasirian H; Nazari M; Abdigoudarzi M; Salehzadeh A
[Ad] Endereço:Department of Medical Entomology, School of Medicine, Hamadan University of Medical Sciences, Hamadan, Iran.
[Ti] Título:Seasonal distribution and faunistic of ticks in the Alashtar county (Lorestan Province), Iran.
[So] Source:Pan Afr Med J;27:284, 2017.
[Is] ISSN:1937-8688
[Cp] País de publicação:Uganda
[La] Idioma:eng
[Ab] Resumo:Introduction: Ticks are non-permanent obligate parasites that have considerable medical-veterinary and zoonosis importance. In this regard a study designed to investigate the distribution and fauna of ticks in the Alashtar county in Iran from April and March 2014. Methods: Ticks were collected from livestock farms and facilities from selected rural and geographically location in the Alashtar county. Based morphological characteristics and reference identification keys, ticks were identified. Results: A total of 549 ticks including 411 hard and 138 soft ticks were found. Ten tick species including (0.36%), (0.36%), (0.18%), (0.18%), (1.45 %), (0.36%), (0.18%), (28.1%), (43.63%) and (25.2%) were identified. Tick seasonal distribution were 47.26%, 22.63%, 14.96% and 15.15% in the spring, summer, autumn and winter, respectively. The tick distribution was more from plain areas (64.96%) than the mountainous areas (35.04%). The rates of the tick contamination were 97.3% and 2.7% in the traditional and industrial livestock's, respectively. The livestock contamination ranks to the hard ticks were cattle (39.51%), sheep (34.15%) and goats (26.34 %), respectively. Chi-square analysis showed a significant difference among the seasonal distribution of the ticks in the spring, summer and autumn or winter; between the tick distribution in the plain and mountainous areas; and between the traditional and industrial livestock's tick contamination (P < 0.05). Conclusion: Present study proves to change the traditional livestock's to the industrial livestock's. These findings highlight the importance of ticks and shows need to their control and tick pest management.
[Mh] Termos MeSH primário: Argasidae
Ixodidae
Estações do Ano
Infestações por Carrapato/epidemiologia
[Mh] Termos MeSH secundário: Animais
Bovinos/parasitologia
Cabras/parasitologia
Irã (Geográfico)/epidemiologia
Gado/parasitologia
Ovinos/parasitologia
Infestações por Carrapato/veterinária
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1712
[Cu] Atualização por classe:171219
[Lr] Data última revisão:
171219
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171201
[St] Status:MEDLINE
[do] DOI:10.11604/pamj.2017.27.284.10341


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[PMID]:29022768
[Au] Autor:Morganti G; Gavaudan S; Canonico C; Ravagnan S; Olivieri E; Diaferia M; Marenzoni ML; Antognoni MT; Capelli G; Silaghi C; Veronesi F
[Ad] Endereço:1 Department of Veterinary Medicine, University of Perugia , Perugia, Italy .
[Ti] Título:Molecular Survey on Rickettsia spp., Anaplasma phagocytophilum, Borrelia burgdorferi Sensu Lato, and Babesia spp. in Ixodes ricinus Ticks Infesting Dogs in Central Italy.
[So] Source:Vector Borne Zoonotic Dis;17(11):743-748, 2017 Nov.
[Is] ISSN:1557-7759
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Dogs are a common feeding hosts for Ixodes ricinus and may act as reservoir hosts for zoonotic tick-borne pathogens (TBPs) and as carriers of infected ticks into human settings. The aim of this work was to evaluate the presence of several selected TBPs of significant public health concern by molecular methods in I. ricinus recovered from dogs living in urban and suburban settings in central Italy. A total of 212 I. ricinus specimens were collected from the coat of domestic dogs. DNA was extracted from each specimen individually and tested for Rickettsia spp., Borrelia burgdorferi sensu lato, Babesia spp., and Anaplasma phagocytophilum, using real-time and conventional PCR protocols, followed by sequencing. Sixty-one ticks (28.8%) tested positive for TBPs; 57 samples were infected by one pathogen, while four showed coinfections. Rickettsia spp. was detected in 39 specimens (18.4%), of which 32 were identified as Rickettsia monacensis and seven as Rickettsia helvetica. Twenty-two samples (10.4%) tested positive for A. phagocytophilum; Borrelia lusitaniae and Borrelia afzelii were detected in two specimens and one specimen, respectively. One tick (0.5%) was found to be positive for Babesia venatorum (EU1). Our findings reveal the significant exposure of dogs to TBPs of public health concern and provide data on the role of dogs in the circulation of I. ricinus-borne pathogens in central Italy.
[Mh] Termos MeSH primário: Anaplasma phagocytophilum/isolamento & purificação
Babesia/isolamento & purificação
Grupo Borrelia Burgdorferi/isolamento & purificação
Doenças do Cão/parasitologia
Ixodes/microbiologia
Rickettsia/isolamento & purificação
[Mh] Termos MeSH secundário: Anaplasma phagocytophilum/genética
Animais
Babesia/genética
Grupo Borrelia Burgdorferi/genética
DNA Bacteriano/genética
DNA de Protozoário/genética
Doenças do Cão/epidemiologia
Cães
Feminino
Itália/epidemiologia
Masculino
Ninfa
Rickettsia/genética
Infestações por Carrapato/epidemiologia
Infestações por Carrapato/parasitologia
Infestações por Carrapato/veterinária
Zoonoses
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (DNA, Bacterial); 0 (DNA, Protozoan)
[Em] Mês de entrada:1711
[Cu] Atualização por classe:171109
[Lr] Data última revisão:
171109
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171013
[St] Status:MEDLINE
[do] DOI:10.1089/vbz.2017.2154


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[PMID]:28922404
[Au] Autor:Quintero V JC; Paternina T LE; Uribe Y A; Muskus C; Hidalgo M; Gil J; Cienfuegos G AV; Osorio Q L; Rojas A C
[Ad] Endereço:Grupo de Ciencias Veterinarias - Centauro, Facultad de Ciencias Agrarias, Universidad de Antioquia, Medellín, Colombia.
[Ti] Título:Eco-epidemiological analysis of rickettsial seropositivity in rural areas of Colombia: A multilevel approach.
[So] Source:PLoS Negl Trop Dis;11(9):e0005892, 2017 Sep.
[Is] ISSN:1935-2735
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Rickettsiosis is a re-emergent infectious disease without epidemiological surveillance in Colombia. This disease is generally undiagnosed and several deadly outbreaks have been reported in the country in the last decade. The aim of this study is to analyze the eco-epidemiological aspects of rickettsial seropositivity in rural areas of Colombia where outbreaks of the disease were previously reported. A cross-sectional study, which included 597 people living in 246 households from nine hamlets in two municipalities of Colombia, was conducted from November 2015 to January 2016. The survey was conducted to collect sociodemographic and household characteristics (exposure) data. Blood samples were collected to determine the rickettsial seropositivity in humans, horses and dogs (IFA, cut-off = 1/128). In addition, infections by rickettsiae were detected in ticks from humans and animals by real-time PCR targeting gltA and ompA genes. Data was analyzed by weighted multilevel clog-log regression model using three levels (person, household and hamlets) and rickettsial seropositivity in humans was the main outcome. Overall prevalence of rickettsial seropositivity in humans was 25.62% (95%CI 22.11-29.12). Age in years (PR = 1.01 95%CI 1.01-1.02) and male sex (PR = 1.65 95%CI 1.43-1.90) were risk markers for rickettsial seropositivity. Working outdoors (PR = 1.20 95%CI 1.02-1.41), deforestation and forest fragmentation for agriculture use (PR = 1.75 95%CI 1.51-2.02), opossum in peridomiciliary area (PR = 1.56 95%CI 1.37-1.79) and a high proportion of seropositive domestic animals in the home (PR20-40% vs <20% = 2.28 95%CI 1.59-3.23 and PR>40% vs <20% = 3.14 95%CI 2.43-4.04) were associated with rickettsial seropositivity in humans. This study showed the presence of Rickettsia antibodies in human populations and domestic animals. In addition, different species of rickettsiae were detected in ticks collected from humans and animals. Our results highlighted the role of domestic animals as sentinels of rickettsial infection to identify areas at risk of transmission, and the importance of preventive measures aimed at curtailing deforestation and the fragmentation of forests as a way of reducing the risk of transmission of emergent and re-emergent pathogens.
[Mh] Termos MeSH primário: Anticorpos Antibacterianos/sangue
Ecossistema
Vigilância Imunológica
Infecções por Rickettsia/epidemiologia
Infecções por Rickettsia/imunologia
Rickettsia/imunologia
Carrapatos/microbiologia
[Mh] Termos MeSH secundário: Adolescente
Adulto
Animais
Animais Domésticos/microbiologia
Colômbia/epidemiologia
Conservação dos Recursos Naturais
Estudos Transversais
Doenças do Cão/epidemiologia
Doenças do Cão/imunologia
Doenças do Cão/microbiologia
Cães
Características da Família
Feminino
Doenças dos Cavalos/epidemiologia
Doenças dos Cavalos/imunologia
Doenças dos Cavalos/microbiologia
Cavalos/imunologia
Cavalos/microbiologia
Seres Humanos
Masculino
Meia-Idade
Prevalência
Rickettsia/isolamento & purificação
Infecções por Rickettsia/transmissão
Infecções por Rickettsia/veterinária
Fatores de Risco
População Rural
Estudos Soroepidemiológicos
Infestações por Carrapato/epidemiologia
Infestações por Carrapato/veterinária
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Antibodies, Bacterial)
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171023
[Lr] Data última revisão:
171023
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170919
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pntd.0005892


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[PMID]:28722568
[Au] Autor:Faccini-Martínez ÁA; Ramírez-Hernández A; Barreto C; Forero-Becerra E; Millán D; Valbuena E; Sánchez-Alfonso AC; Imbacuán-Pantoja WO; Cortés-Vecino JA; Polo-Terán LJ; Yaya-Lancheros N; Jácome J; Palomar AM; Santibáñez S; Portillo A; Oteo JA; Hidalgo M
[Ad] Endereço:Programa de Pós-Graduação em Doenças Infecciosas, Centro de Ciências da Saúde, Universidade Federal do Espírito Santo, Vitória, ES, Brazil.
[Ti] Título:Epidemiology of Spotted Fever Group Rickettsioses and Acute Undifferentiated Febrile Illness in Villeta, Colombia.
[So] Source:Am J Trop Med Hyg;97(3):782-788, 2017 Sep.
[Is] ISSN:1476-1645
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Etiology of acute undifferentiated febrile syndrome (AUFS) is often unknown, leading to inaccurate diagnosis and treatment. Villeta town has been identified as an endemic area for spotted fever group (SFG) rickettsioses but little is known about possible amplifier hosts and other species different from . Besides, few studies have approached other AUFS etiologies in the region. We investigated the role of dengue, leptospirosis, rickettsioses, human anaplasmosis, and Q fever as possible causes of AUFS in patients from Villeta. Sera specimens and ticks from animals as well as ticks from vegetation were studied for the presence of different spp. Among 104 sera from patients with AUFS, 16.4%, 24.0%, and 2.9% patients seroconverted to dengue, , and SFG , respectively, with a case of probable coinfection or cross-reaction with . None of the samples were reactive for . Sera samples from 74 horses, 118 dogs, and 62 bovines were collected and showed 33.8%, 14.4%, and 50.0% of seroprevalence for SFG , respectively. A total of 1,287 ixodid ticks were collected from animals/vegetation and processed in pools for polymerase chain reaction. Among them, 1.7% was positive for genes, and , , and spp. were found. These results confirm the circulation of dengue, different SFG species and the relevance of other etiologies like leptospirosis and human anaplasmosis. Further studies must identify different epidemiological variables to establish proper surveillance and control programs.
[Mh] Termos MeSH primário: Infecções por Rickettsia/microbiologia
Rickettsia/classificação
Carrapatos/microbiologia
[Mh] Termos MeSH secundário: Doença Aguda
Adolescente
Adulto
Animais
Criança
Colômbia/epidemiologia
Feminino
Seres Humanos
Masculino
Mamíferos
Meia-Idade
Infecções por Rickettsia/epidemiologia
Estudos Soroepidemiológicos
Infestações por Carrapato/epidemiologia
Infestações por Carrapato/veterinária
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171018
[Lr] Data última revisão:
171018
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:170720
[St] Status:MEDLINE
[do] DOI:10.4269/ajtmh.16-0442


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[PMID]:28658173
[Au] Autor:Nakao Y; Tanigawa T; Shibata R
[Ad] Endereço:aDepartment of Otolaryngology, Yoshida General Hospital, Hiroshima bDepartment of Otolaryngology, Aichi Medical University, Aichi cDepartment of Cardiology, Nagoya University, Nagoya, Japan.
[Ti] Título:Human otoacariasis caused by Amblyomma testudinarium: Diagnosis and management: Case report.
[So] Source:Medicine (Baltimore);96(26):e7394, 2017 Jun.
[Is] ISSN:1536-5964
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:RATIONALE: Tick infestation of the external auditory canal (EAC) constitutes <1% of all patients presenting with ear complaints. Consequently, parameters for the diagnosis and management of ticks in the EAC have not been established. PATIENT CONCERNS: We report 2 cases of EAC infestation by Amblyomma testudinarium in 2 female patients, aged 12- and 72 years old. DIAGNOSES INTERVENTIONS AND OUTCOMES: In both patients, otoscopic examination revealed engorged ticks attached to the ear canal. The 12-year-old girl had a narrow EAC, necessitating slight dislodging of the tick to determine if its mouth parts were embedded in the EAC skin. The tick's mouth parts were confirmed to be free, enabling complete removal of the tick. The 72-year-old woman had a wide EAC, enabling tick removal using Hartman's forceps because the tick's mouth parts were confirmed to be free of the skin. Prophylactic tetracycline (200 mg/day) was administered to each patient for 7 days; neither showed any signs of fever or rash. LESSONS: This report describes 2 patients with A testudinarium infestation of the EAC, and proposes a simple, noninvasive protocol for determining if the tick is anchored to the ear canal.
[Mh] Termos MeSH primário: Meato Acústico Externo/parasitologia
Ixodidae
Infestações por Carrapato/diagnóstico
[Mh] Termos MeSH secundário: Idoso
Animais
Antibacterianos/uso terapêutico
Antibioticoprofilaxia
Criança
Seres Humanos
Masculino
Otoscopia
Tetraciclina/uso terapêutico
Infestações por Carrapato/terapia
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Anti-Bacterial Agents); F8VB5M810T (Tetracycline)
[Em] Mês de entrada:1707
[Cu] Atualização por classe:170718
[Lr] Data última revisão:
170718
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:170629
[St] Status:MEDLINE
[do] DOI:10.1097/MD.0000000000007394


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[PMID]:28619006
[Au] Autor:Sollero BP; Junqueira VS; Gomes CCG; Caetano AR; Cardoso FF
[Ad] Endereço:Embrapa Pecuária Sul, Caixa Postal 242 - BR 153 - Km 633, Bagé, Rio Grande do Sul, 96.401-970, Brazil. bruna.sollero@embrapa.br.
[Ti] Título:Tag SNP selection for prediction of tick resistance in Brazilian Braford and Hereford cattle breeds using Bayesian methods.
[So] Source:Genet Sel Evol;49(1):49, 2017 Jun 15.
[Is] ISSN:1297-9686
[Cp] País de publicação:France
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Cattle resistance to ticks is known to be under genetic control with a complex biological mechanism within and among breeds. Our aim was to identify genomic segments and tag single nucleotide polymorphisms (SNPs) associated with tick-resistance in Hereford and Braford cattle. The predictive performance of a very low-density tag SNP panel was estimated and compared with results obtained with a 50 K SNP dataset. RESULTS: BayesB (π = 0.99) was initially applied in a genome-wide association study (GWAS) for this complex trait by using deregressed estimated breeding values for tick counts and 41,045 SNP genotypes from 3455 animals raised in southern Brazil. To estimate the combined effect of a genomic region that is potentially associated with quantitative trait loci (QTL), 2519 non-overlapping 1-Mb windows that varied in SNP number were defined, with the top 48 windows including 914 SNPs and explaining more than 20% of the estimated genetic variance for tick resistance. Subsequently, the most informative SNPs were selected based on Bayesian parameters (model frequency and t-like statistics), linkage disequilibrium and minor allele frequency to propose a very low-density 58-SNP panel. Some of these tag SNPs mapped close to or within genes and pseudogenes that are functionally related to tick resistance. Prediction ability of this SNP panel was investigated by cross-validation using K-means and random clustering and a BayesA model to predict direct genomic values. Accuracies from these cross-validations were 0.27 ± 0.09 and 0.30 ± 0.09 for the K-means and random clustering groups, respectively, compared to respective values of 0.37 ± 0.08 and 0.43 ± 0.08 when using all 41,045 SNPs and BayesB with π = 0.99, or of 0.28 ± 0.07 and 0.40 ± 0.08 with π = 0.999. CONCLUSIONS: Bayesian GWAS model parameters can be used to select tag SNPs for a very low-density panel, which will include SNPs that are potentially linked to functional genes. It can be useful for cost-effective genomic selection tools, when one or a few key complex traits are of interest.
[Mh] Termos MeSH primário: Doenças dos Bovinos/genética
Doenças dos Bovinos/parasitologia
Estudo de Associação Genômica Ampla/métodos
Polimorfismo de Nucleotídeo Único
Infestações por Carrapato/veterinária
[Mh] Termos MeSH secundário: Animais
Teorema de Bayes
Bovinos
Resistência à Doença/genética
Predisposição Genética para Doença
Modelos Genéticos
Infestações por Carrapato/genética
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171006
[Lr] Data última revisão:
171006
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170617
[St] Status:MEDLINE
[do] DOI:10.1186/s12711-017-0325-2



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