Base de dados : MEDLINE
Pesquisa : C04.557.450.565.465.249.500 [Categoria DeCS]
Referências encontradas : 48 [refinar]
Mostrando: 1 .. 10   no formato [Detalhado]

página 1 de 5 ir para página              

  1 / 48 MEDLINE  
              next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:25603535
[Au] Autor:Ma SP; Hardy TG
[Ad] Endereço:Department of Ophthalmology, The Royal Melbourne Hospital, Parkville, Australia.
[Ti] Título:Solitary Mastocytoma of the Eyelid in an Adult Patient With Prolidase Deficiency.
[So] Source:Ophthal Plast Reconstr Surg;33(1):e10-e13, 2017 Jan/Feb.
[Is] ISSN:1537-2677
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Prolidase deficiency and solitary mastocytoma of the eyelid are both exceedingly rare. Prolidase deficiency is an inherited connective tissue disorder that has systemic sequelae, such as intractable skin ulceration, poor wound healing, recurrent infections, and intellectual impairment. Cutaneous mastocytoma is an isolated, aberrant cutaneous aggregation of mast cells. A case of an adult with severe prolidase deficiency who developed cutaneous mastocytoma of the eyelid was presented. To the authors' knowledge, adult-onset solitary mastocytoma of the eyelid has never been reported previously.
[Mh] Termos MeSH primário: Neoplasias Palpebrais/patologia
Mastocitoma Cutâneo/patologia
Deficiência de Prolidase/complicações
[Mh] Termos MeSH secundário: Neoplasias Palpebrais/etiologia
Seres Humanos
Masculino
Mastocitoma Cutâneo/etiologia
Meia-Idade
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Em] Mês de entrada:1703
[Cu] Atualização por classe:170817
[Lr] Data última revisão:
170817
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:150121
[St] Status:MEDLINE
[do] DOI:10.1097/IOP.0000000000000376


  2 / 48 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:27716984
[Au] Autor:Camus M; Priest H; Koehler J; Driskell E; Ilha M; Rakich P; Krimer P
[Ad] Endereço:Veterinary Pathology, University of Georgia, Athens, GA, USA.
[Ti] Título:Letter to the Editor re Hergt et al "Use of a 2-tier histologic grading system for canine cutaneous mast cell tumors on cytology specimens".
[So] Source:Vet Clin Pathol;45(4):531, 2016 12.
[Is] ISSN:1939-165X
[Cp] País de publicação:United States
[La] Idioma:eng
[Mh] Termos MeSH primário: Mastócitos
Mastocitoma Cutâneo
[Mh] Termos MeSH secundário: Animais
Doenças do Cão
Cães
Neoplasias Cutâneas
[Pt] Tipo de publicação:LETTER; COMMENT
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171006
[Lr] Data última revisão:
171006
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161008
[St] Status:MEDLINE
[do] DOI:10.1111/vcp.12407


  3 / 48 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
[PMID]:27617456
[Au] Autor:Lozano Masdemont B; Campos Dominguez M; Gomez-Recuero Munoz L; Moreno Garcia B; Parra Blanco V; Suarez Fernandez R
[Ad] Endereço:Hospital General Universitario Gregorio Marañón, Madrid. belenmasdemont@gmail.com.
[Ti] Título:Congenital cutaneous Langerhans cell histiocytosis and cutaneous mastocytoma in a child.
[So] Source:Dermatol Online J;22(4), 2016 Apr 18.
[Is] ISSN:1087-2108
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Langerhans cell histiocytosis and mastocytoma are clonal disorders of bone-marrow-derived cells, most commonly seen in the pediatric age. Infiltration of mast cells and Langerhans cells in the same lesion has been published before, but, to our knowledge, this is the first time that the occurrence of two mastocytomas and Langerhans cell histiocytosis is reported. It could be hypothesized that both clonal disorders of bone-marrow-derived cells could have a common origin.
[Mh] Termos MeSH primário: Histiocitose de Células de Langerhans/congênito
Mastocitoma Cutâneo/congênito
[Mh] Termos MeSH secundário: Histiocitose de Células de Langerhans/complicações
Histiocitose de Células de Langerhans/patologia
Seres Humanos
Recém-Nascido
Masculino
Mastocitoma Cutâneo/complicações
Mastocitoma Cutâneo/patologia
Dermatopatias/complicações
Dermatopatias/congênito
Dermatopatias/patologia
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Em] Mês de entrada:1704
[Cu] Atualização por classe:170425
[Lr] Data última revisão:
170425
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160913
[St] Status:MEDLINE


  4 / 48 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:27578524
[Au] Autor:Vilalta L; Meléndez-Lazo A; Doria G; Ramis A; Solano-Gallego L; Pastor J; Martorell J
[Ad] Endereço:Fundació Hospital Clínic Veterinari, Spain. Electronic address: lauravilalta84@hotmail.com.
[Ti] Título:Clinical, Cytological, Histological and Immunohistochemical Features of Cutaneous Mast Cell Tumours in Ferrets (Mustela putorius furo).
[So] Source:J Comp Pathol;155(4):346-355, 2016 Nov.
[Is] ISSN:1532-3129
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Cutaneous mast cell tumours (cMCTs) are one of the most common cutaneous tumours in ferrets (Mustela putorius furo). However, limited information is available regarding cytological and histological features of these tumours and studies evaluating KIT expression are lacking in this species. The aims of this prospective study were to describe the most common clinical, cytological and histological features of cMCTs in ferrets and to compare the usefulness of different staining techniques in the diagnosis of these tumours in ferrets as well as evaluating KIT expression in neoplastic mast cells (MCs) by immunohistochemistry. Macroscopically, the tumours were small, round to plaque-like and frequently associated with surface crusting. The most common locations were the extremities and the trunk. MC granules were stained in all cases using toluidine blue (TB) and Wright-Giemsa stains in cytological specimens, but none stained with modified Wright's stain. Haematoxylin and eosin and TB on histological sections failed to stain MC granules in all the cases. Cytological and histological examination revealed low to moderate anisocytosis and anisokaryosis. An infiltrative rather than a delineated or encapsulated growth pattern was noted histologically in all cases. Eosinophilic infiltration was not uncommon and 'collagenolysis' was detected on cytological and histological examination. KIT expression was detected in all cases evaluated. In approximately one third of the cases the MCs exhibited KIT labelling pattern I and in the remaining ferrets, KIT pattern III. No correlation was found between KIT expression pattern and biological behaviour.
[Mh] Termos MeSH primário: Furões
Mastocitoma Cutâneo/veterinária
[Mh] Termos MeSH secundário: Animais
Imuno-Histoquímica
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1704
[Cu] Atualização por classe:170420
[Lr] Data última revisão:
170420
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160901
[St] Status:MEDLINE


  5 / 48 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:27256023
[Au] Autor:Giantin M; Baratto C; Marconato L; Vascellari M; Mutinelli F; Dacasto M; Granato A
[Ad] Endereço:Dipartimento di Biomedicina Comparata e Alimentazione, Università degli Studi di Padova, Viale dell'Università 16, I-35020 Agripolis Legnaro (Padova), Italy. Electronic address: mery.giantin@unipd.it.
[Ti] Título:Transcriptomic analysis identified up-regulation of a solute carrier transporter and UDP glucuronosyltransferases in dogs with aggressive cutaneous mast cell tumours.
[So] Source:Vet J;212:36-43, 2016 Jun.
[Is] ISSN:1532-2971
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Gene expression analyses have been recently used in cancer research to identify genes associated with tumorigenesis and potential prognostic markers or therapeutic targets. In the present study, the transcriptome of dogs that had died because of mast cell tumours (MCTs) was characterised to identify a fingerprint having significant influence on prognosis determination and treatment selection. A dataset (GSE50433) obtained using a commercial canine DNA microarray platform was used. The transcriptome of seven biopsies obtained from dogs with histologically confirmed, surgically removed MCTs, treated with chemotherapy, and dead for MCT-related causes, was compared with the transcriptional portrait of 40 samples obtained from dogs with histologically confirmed, surgically removed MCTs and that were still alive at the end of the follow-up period. Among the differentially expressed genes (DEGs), eight transcripts were validated by quantitative real time PCR and their mRNA levels were measured in a cohort of 22 additional MCTs. Statistical analysis identified 375 DEGs (fold change 2, false discovery rate 5%). The functional annotation analysis indicated that the DEGs were associated with drug metabolism and cell cycle pathways. Particularly, members of solute carrier transporter (SLC) and UDP glucuronosyltransferase (UGT) gene families were identified as dysregulated. Principal component analysis (PCA) of the 22 additional MCTs identified the separate cluster dogs dead for MCT-related causes. SLCs and UGTs have been recently recognised in human cancer as important key factors in tumour progression and chemo-resistance. An in-depth analysis of their roles in aggressive canine MCT is warranted in future studies.
[Mh] Termos MeSH primário: Sistemas de Transporte de Aminoácidos Neutros/genética
Doenças do Cão/genética
Regulação Neoplásica da Expressão Gênica
Glucuronosiltransferase/genética
Mastocitoma Cutâneo/veterinária
Neoplasias Cutâneas/genética
[Mh] Termos MeSH secundário: Sistemas de Transporte de Aminoácidos Neutros/metabolismo
Animais
Cães
Feminino
Perfilação da Expressão Gênica/veterinária
Glucuronosiltransferase/metabolismo
Masculino
Mastócitos/metabolismo
Mastocitoma Cutâneo/genética
Transcriptoma
Regulação para Cima
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Amino Acid Transport Systems, Neutral); EC 2.4.1.17 (Glucuronosyltransferase)
[Em] Mês de entrada:1705
[Cu] Atualização por classe:170817
[Lr] Data última revisão:
170817
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160604
[St] Status:MEDLINE


  6 / 48 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:26564778
[Au] Autor:Kolivras A; André J; Thompson C; Sass U; Fraitag S
[Ad] Endereço:Department of Dermatology and Dermatopathology, Saint-Pierre, Brugmann and HUDERF Hospitals, Université Libre de Bruxelles, Brussels, Belgium.
[Ti] Título:Pseudoangiomatous xanthelasmoid mastocytosis: two case reports showing the hypervascularity of this rare variant of cutaneous mastocytosis.
[So] Source:J Cutan Pathol;43(4):388-93, 2016 Apr.
[Is] ISSN:1600-0560
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Xanthelasmoid mastocytosis or xanthelasmoidea is a rare clinical variant of cutaneous mastocytosis characterized by a yellow hue of the clinical lesions, which are often misdiagnosed as juvenile xanthogranuloma. We present two pediatric cases of xanthelasmoid mastocytosis presenting as isolated mastocytomas, which are notable histopathologically for their hypervascularity. This pseudoangiomatous variant of cutaneous mastocytosis is important for pathologists to have knowledge of, so that a diagnosis of a vascular tumor is not rendered accidentally. The yellow hue has previously been explained by the usual deep and solid dermal mast cell infiltrate. In the two presented cases, however, the mast cell infiltrate was sparse, and the yellow color cannot be related to infiltrate density. We believe that the hypervascularity is at least one factor in the production of clinical xanthelasmoid appearance, and we propose the term 'pseudoangiomatous xanthelasmoid mastocytosis' to properly describe this rare variant of cutaneous mastocytosis.
[Mh] Termos MeSH primário: Mastocitoma Cutâneo
Xantogranuloma Juvenil
[Mh] Termos MeSH secundário: Criança
Feminino
Seres Humanos
Recém-Nascido
Masculino
Mastocitoma Cutâneo/irrigação sanguínea
Mastocitoma Cutâneo/diagnóstico
Mastocitoma Cutâneo/metabolismo
Mastocitoma Cutâneo/patologia
Xantogranuloma Juvenil/diagnóstico
Xantogranuloma Juvenil/metabolismo
Xantogranuloma Juvenil/patologia
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Em] Mês de entrada:1612
[Cu] Atualização por classe:161230
[Lr] Data última revisão:
161230
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:151114
[St] Status:MEDLINE
[do] DOI:10.1111/cup.12651


  7 / 48 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:25471152
[Au] Autor:Patrizi A; Tabanelli M; Neri I; Virdi A
[Ad] Endereço:Dermatology, Department of Experimental, Diagnostic and Specialty Medicine, S. Orsola-Malpighi Hospital, University of Bologna, Bologna, Italy.
[Ti] Título:Topical corticosteroids versus "wait and see" in the management of solitary mastocytoma in pediatric patients: a long-term follow-up.
[So] Source:Dermatol Ther;28(2):57-61, 2015 Mar-Apr.
[Is] ISSN:1529-8019
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Management of patients affected by mastocytoma (MS) includes avoiding triggering factors of mast cell degranulation, and administration of symptomatic treatment. We evaluated topical steroid treatment efficiency on the clinical course of MS in a group of patients, comparing the results with another untreated group.We retrospectively evaluated clinical data of 176 patients under 15 years of age, affected by MS and referred to our Dermatological Pediatric Service from 1996 to 2010. Ninety-one of 176 children were treated with topical steroids. Follow-up was possible in 130 of 176 patients and lasted for 56.3 months on average. We compared 62 treated and 68 untreated patients. There was not statistic difference between the two groups: (i) in the number of healed or partially improved cases; and (ii) in the time of partial regression, although it is quicker with therapy. The time of healing is 16.4 months (on average) with treatment, and 34.7 months (on average, p = 0.001) without any treatment. The resolution of MS is independent of therapy administration, but the time of healing is statistically faster using the local steroids. An appropriate treatment with them is effective and safe, considering the long time needed for spontaneous resolution.
[Mh] Termos MeSH primário: Corticosteroides/administração & dosagem
Mastocitoma Cutâneo/tratamento farmacológico
Pele/efeitos dos fármacos
Conduta Expectante
[Mh] Termos MeSH secundário: Administração Cutânea
Adolescente
Corticosteroides/efeitos adversos
Criança
Pré-Escolar
Feminino
Seguimentos
Seres Humanos
Lactente
Recém-Nascido
Masculino
Mastocitoma Cutâneo/diagnóstico
Indução de Remissão
Estudos Retrospectivos
Pele/patologia
Fatores de Tempo
Resultado do Tratamento
[Pt] Tipo de publicação:COMPARATIVE STUDY; JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Adrenal Cortex Hormones)
[Em] Mês de entrada:1605
[Cu] Atualização por classe:150402
[Lr] Data última revisão:
150402
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:141205
[St] Status:MEDLINE
[do] DOI:10.1111/dth.12186


  8 / 48 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:25461481
[Au] Autor:Yabe T; Hosoda-Yabe R; Sakai H; Kanamaru Y; Kiso M
[Ad] Endereço:Department of Applied Life Science, Faculty of Applied Biological Sciences, Gifu University, Gifu 501-1193, Japan. Electronic address: yabet@gifu-u.ac.jp.
[Ti] Título:Development of a photoreactive probe-based system for detecting heparin.
[So] Source:Anal Biochem;472:1-6, 2015 Mar 01.
[Is] ISSN:1096-0309
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:We previously identified a peptide heparin-associated peptide Y (HappY) that binds specifically to heparin. In this article, we report a novel heparin detection system using chemically modified HappY as a probe. The photoreactive HappY probe was serially diluted and dispensed into a 96-well plate coated with biotinylated heparin. After ultraviolet irradiation, the HappY probe crosslinked to the heparin on the plate was detected with fluorescein isothiocyanate-conjugated streptavidin. Furthermore, the photoreactive HappY probe was used to stain cutaneous tissue sections obtained from dermatitis-affected or mastocytoma-affected cats and dogs. The photoreactive HappY probe stained limited resident mast cells in the connective tissue of skin compared with the anti-heparan sulfate monoclonal antibody 10E4, suggesting that the probe can be used to distinguish the structure of heparin in tissues. The interactions between glycosaminoglycans and proteins in vivo tend to be weak. Therefore, our method for enhancing such weak interactions may be a promising tool for intermolecular interaction studies in glycobiology research.
[Mh] Termos MeSH primário: Dermatite/metabolismo
Corantes Fluorescentes/química
Heparina/metabolismo
Mastócitos/metabolismo
Mastocitoma Cutâneo/metabolismo
Peptídeos/química
[Mh] Termos MeSH secundário: Animais
Gatos
Dermatite/patologia
Cães
Fluoresceína/química
Mastócitos/patologia
Mastocitoma Cutâneo/patologia
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (Fluorescent Dyes); 0 (Peptides); 9005-49-6 (Heparin); TPY09G7XIR (Fluorescein)
[Em] Mês de entrada:1509
[Cu] Atualização por classe:151119
[Lr] Data última revisão:
151119
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:141203
[St] Status:MEDLINE


  9 / 48 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:25442476
[Au] Autor:Barete S
[Ad] Endereço:UPMC Paris 6, unité fonctionnelle de dermatologie, hôpital Pitié-Salpêtrière, Sorbonne universités, AP-HP, 47-83, boulevard de l'Hôpital, 75013 Paris, France; UPMC Paris 6, service de dermatologie-allergologie, hôpital Tenon, Sorbonne universités, AP-HP, 4, rue de la Chine, 75020 Paris, France; Centre de référence des mastocytoses CEREMAST, hôpital Necker, 149, rue de Sèvres, 75015 Paris, France. Electronic address: stephane.barete@psl.aphp.fr.
[Ti] Título:[Mastocytosis].
[Ti] Título:Les mastocytoses..
[So] Source:Ann Dermatol Venereol;141(11):698-714; quiz 697, 715, 2014 Nov.
[Is] ISSN:0151-9638
[Cp] País de publicação:France
[La] Idioma:fre
[Mh] Termos MeSH primário: Mastocitose Cutânea/diagnóstico
[Mh] Termos MeSH secundário: Doença de Darier/diagnóstico
Diagnóstico Diferencial
Seres Humanos
Mastocitoma Cutâneo/diagnóstico
Mastocitose Cutânea/etiologia
Mastocitose Cutânea/terapia
Mastocitose Sistêmica/diagnóstico
Telangiectasia/diagnóstico
Urticaria Pigmentosa/diagnóstico
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Em] Mês de entrada:1507
[Cu] Atualização por classe:141202
[Lr] Data última revisão:
141202
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:141203
[St] Status:MEDLINE


  10 / 48 MEDLINE  
              first record previous record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:25257118
[Au] Autor:Bourji L; Kurban M; Abbas O
[Ad] Endereço:Department of Dermatology, American University of Beirut Medical Center, Beirut, Lebanon.
[Ti] Título:Solitary mastocytoma mimicking granuloma faciale.
[So] Source:Int J Dermatol;53(12):e587-8, 2014 Dec.
[Is] ISSN:1365-4632
[Cp] País de publicação:England
[La] Idioma:eng
[Mh] Termos MeSH primário: Granuloma/patologia
Mastocitoma Cutâneo/patologia
Dermatoses do Couro Cabeludo/patologia
Couro Cabeludo/patologia
[Mh] Termos MeSH secundário: Adolescente
Biópsia
Diagnóstico Diferencial
Seres Humanos
Masculino
[Pt] Tipo de publicação:CASE REPORTS; LETTER
[Em] Mês de entrada:1507
[Cu] Atualização por classe:141127
[Lr] Data última revisão:
141127
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:140927
[St] Status:MEDLINE
[do] DOI:10.1111/ijd.12577



página 1 de 5 ir para página              
   


Refinar a pesquisa
  Base de dados : MEDLINE Formulário avançado   

    Pesquisar no campo  
1  
2
3
 
           



Search engine: iAH v2.6 powered by WWWISIS

BIREME/OPAS/OMS - Centro Latino-Americano e do Caribe de Informação em Ciências da Saúde