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[PMID]:29211227
[Au] Autor:Pomerantzeff PMA; Veronese ET; Dinato FJ; Jatene FB
[Ad] Endereço:Instituto do Coração do Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo (InCor-HCFMUSP), São Paulo, SP, Brazil.
[Ti] Título:Resection of Left Atrial Myxoma in a Patient with Retrosternal Gastric Tube: a Case Report.
[So] Source:Braz J Cardiovasc Surg;32(5):438-441, 2017 Sep-Oct.
[Is] ISSN:1678-9741
[Cp] País de publicação:Brazil
[La] Idioma:eng
[Ab] Resumo:The median sternotomy remains the standard approach in cardiovascular surgery but, in some conditions, it can be considered difficult to perform, especially in patients with history of esophagectomy. This case report describes a successful resection of a left atrial myxoma through a right anterolateral thoracotomy approach in a patient with a previous retrosternal gastric tube reconstruction. The decision for the best surgical approach was made after a heart surgery team discussion. Through this surgical access, a safe and excellent exposure of the left atrium was possible, and a complete resection of the myxoma was performed without any injury to the gastric tube.
[Mh] Termos MeSH primário: Neoplasias Cardíacas/cirurgia
Mixoma/cirurgia
[Mh] Termos MeSH secundário: Idoso
Gastrostomia
Átrios do Coração/patologia
Átrios do Coração/cirurgia
Seres Humanos
Masculino
Toracotomia
Resultado do Tratamento
[Pt] Tipo de publicação:CASE REPORTS
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180216
[Lr] Data última revisão:
180216
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171207
[St] Status:MEDLINE


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[PMID]:29182840
[Au] Autor:Shimazaki T; Kimura H; Tsuchiya H; Yanagisawa T; Ogiwara M; Horigome M; Mawatari E; Ikei H; Yazaki Y
[Ti] Título:[A cse f myocardial infarction due to tumor embolus from myxoma proved by thrombus auction catheter.]
[So] Source:Nihon Naika Gakkai Zasshi;105(5):874-878, 2016 May.
[Is] ISSN:0021-5384
[Cp] País de publicação:Japan
[La] Idioma:jpn
[Mh] Termos MeSH primário: Neoplasias Cardíacas/complicações
Infarto do Miocárdio/etiologia
Mixoma/complicações
Trombose/terapia
[Mh] Termos MeSH secundário: Idoso
Cateteres Cardíacos
Feminino
Seres Humanos
Trombose/etiologia
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180214
[Lr] Data última revisão:
180214
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171129
[St] Status:MEDLINE


  3 / 5938 MEDLINE  
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[PMID]:29375114
[Au] Autor:Yamashita M; Eguchi K; Ogawa M; Takahashi K; Nagai M; Shimpo M; Misawa Y; Kario K
[Ad] Endereço:Department of Medicine, Jichi Medical University School of Medicine.
[Ti] Título:A Case of Left Atrial Myxoma Whose Initial Symptom Was Finger Ischemic Symptom.
[So] Source:Int Heart J;59(1):233-236, 2018.
[Is] ISSN:1349-3299
[Cp] País de publicação:Japan
[La] Idioma:eng
[Ab] Resumo:We experienced a 45-year-old Japanese man who was transferred to our hospital complaining of acute onset of pain and pallor in the right lower limb. Two years earlier, he had complained of repetitive pain at rest and pallor in the left third and fourth fingers. The physical exam and angiography demonstrated occlusion of finger arteries, however we could not reach final diagnosis. Acute arterial occlusive disease in the right lower limb was suspected. Transthoracic echocardiography demonstrated a gross tumor in the left atrium, which suggested left atrial myxoma. An emergency tumorectomy was successfully conducted. Pathologically, the fragile tumor and resultant thrombosis could have caused the patient's peripheral circulatory failure at least two years prior to this episode. A rigorous systemic survey is important even when the ischemic symptom is localized in peripheral circulation.
[Mh] Termos MeSH primário: Dedos/irrigação sanguínea
Neoplasias Cardíacas/complicações
Isquemia/etiologia
Mixoma/complicações
[Mh] Termos MeSH secundário: Procedimentos Cirúrgicos Cardíacos
Ecocardiografia
Átrios do Coração
Neoplasias Cardíacas/diagnóstico
Neoplasias Cardíacas/cirurgia
Seres Humanos
Isquemia/diagnóstico
Imagem por Ressonância Magnética
Masculino
Meia-Idade
Mixoma/diagnóstico
Mixoma/cirurgia
Tomografia Computadorizada por Raios X
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180205
[Lr] Data última revisão:
180205
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180130
[St] Status:MEDLINE
[do] DOI:10.1536/ihj.16-394


  4 / 5938 MEDLINE  
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[PMID]:29172755
[Au] Autor:Garcia-Carretero R; Vela BB; Martínez-Quesada G; San Jose Montano B
[Ad] Endereço:a Department of Internal Medicine , Mostoles University Hospital , Mostoles ( Madrid ), Spain.
[Ti] Título:Demographic and clinical features of atrial myxomas: A case series analysis.
[So] Source:Acute Card Care;18(3):65-69, 2016 Sep.
[Is] ISSN:1748-295X
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:AIM: Cardiac myxomas are uncommon tumors and have a wide clinical spectrum. Their diagnosis can therefore be elusive because symptoms are nonspecific and misleading. Our aim was to characterize and analyze the clinical findings in patients presenting with cardiac myxomas. METHODS: We conducted a retrospective, hospital-based case study using the electronic records of a Spanish general hospital, caring for a population of 155,000. Patients' data were collected for the period between 2000 and 2016. Demographic data and clinical features were analyzed. RESULTS: Our series included 22 patients over a 15-year period (annual incidence of 0.94 patients per 100,000 inhabitants). Men were predominant (68%) and the median age was 69 years. Cardiac (40.9%), systemic (27.3%), and neurological manifestations (13.6%) were the main clinical features. Left atrium (81.8%) was the predominant location. Surgical treatment was performed in all patients and the overall outcome was good in all cases. CONCLUSIONS: Cardiac myxomas are uncommon, benign tumors, predominantly located in the left atrium and mainly affecting middle-aged and elderly male patients. Congestive heart failure, stroke, and systemic symptoms, although misleading and nonspecific, are the most frequent forms of clinical presentation.
[Mh] Termos MeSH primário: Átrios do Coração/cirurgia
Insuficiência Cardíaca/cirurgia
Neoplasias Cardíacas/cirurgia
Mixoma/epidemiologia
Mixoma/cirurgia
[Mh] Termos MeSH secundário: Adulto
Distribuição por Idade
Idoso
Idoso de 80 Anos ou mais
Feminino
Insuficiência Cardíaca/diagnóstico
Neoplasias Cardíacas/diagnóstico
Seres Humanos
Incidência
Masculino
Meia-Idade
Mixoma/diagnóstico
Estudos Retrospectivos
Caracteres Sexuais
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1801
[Cu] Atualização por classe:180116
[Lr] Data última revisão:
180116
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171128
[St] Status:MEDLINE
[do] DOI:10.1080/17482941.2017.1398827


  5 / 5938 MEDLINE  
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[PMID]:28885430
[Au] Autor:Song M; Glasgow M; Murugan P; Rivard C
[Ad] Endereço:Department of Obstetrics, Gynecology and Women's Health and the Department of Pathology and Laboratory Medicine, University of Minnesota, Minneapolis, Minnesota.
[Ti] Título:Aggressive Angiomyxoma of the Vulva and Bladder.
[So] Source:Obstet Gynecol;130(4):885-888, 2017 Oct.
[Is] ISSN:1873-233X
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Aggressive angiomyxoma is a rare, locally infiltrative tumor, frequently occurring in female patients. Although wide local excision is considered standard therapy, radical surgery may be needed. CASE: A 49-year-old woman presented with an aggressive angiomyxoma involving the vulva and bladder. Given the hormone receptor status and size of the tumor, the patient was initially treated with fulvestrant and goserelin acetate in an attempt to reduce the size of the mass. She was followed up at 1- to 3-month intervals; after 6 months of treatment, owing to increasing size of the mass and worsening symptoms, the decision was made to proceed with radical surgery. CONCLUSION: Although a less radical surgical approach is preferred, radical surgery is possible for treatment of aggressive angiomyxoma when needed.
[Mh] Termos MeSH primário: Mixoma/diagnóstico
Neoplasias da Bexiga Urinária/diagnóstico
Neoplasias Vulvares/diagnóstico
[Mh] Termos MeSH secundário: Antineoplásicos Hormonais/administração & dosagem
Diagnóstico Diferencial
Estradiol/administração & dosagem
Estradiol/análogos & derivados
Feminino
Gosserrelina/administração & dosagem
Seres Humanos
Meia-Idade
Mixoma/tratamento farmacológico
Mixoma/cirurgia
Terapia Neoadjuvante
Invasividade Neoplásica
Neoplasias da Bexiga Urinária/tratamento farmacológico
Neoplasias da Bexiga Urinária/cirurgia
Neoplasias Vulvares/tratamento farmacológico
Neoplasias Vulvares/cirurgia
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Antineoplastic Agents, Hormonal); 0F65R8P09N (Goserelin); 22X328QOC4 (fulvestrant); 4TI98Z838E (Estradiol)
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171002
[Lr] Data última revisão:
171002
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:170909
[St] Status:MEDLINE
[do] DOI:10.1097/AOG.0000000000002254


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[PMID]:28832803
[Au] Autor:Patel K; Rahul K; Tarsaria M; Malhotra A
[Ad] Endereço:Department of Cardiovascular and Thoracic Surgery of U. N. Mehta Institute of Cardiology and Research Center (affiliated to BJ Medical College, Ahmedabad), Gujarat, India.
[Ti] Título:Left Atrial Myxoma Following Coronary Artery Bypass Grafting with Patient Coronary Arterial Grafts: a Rarity.
[So] Source:Braz J Cardiovasc Surg;32(3):228-230, 2017 May-Jun.
[Is] ISSN:1678-9741
[Cp] País de publicação:Brazil
[La] Idioma:eng
[Ab] Resumo:The development of left atrial myxoma after coronary artery bypass graft surgery is a rare entity. A 60-year-old man with previous off-pump coronary artery bypass grafting four years ago with patent coronary grafts was diagnosed with left atrial mass. The patient underwent successful resection of the same through minimally invasive right anterolateral thoracotomy. Histopathology of the atrial mass confirmed the diagnosis of atrial myxoma.
[Mh] Termos MeSH primário: Ponte de Artéria Coronária/efeitos adversos
Neoplasias Cardíacas/etiologia
Neoplasias Cardíacas/patologia
Mixoma/etiologia
Mixoma/patologia
[Mh] Termos MeSH secundário: Ponte Cardiopulmonar/métodos
Átrios do Coração/patologia
Neoplasias Cardíacas/cirurgia
Seres Humanos
Masculino
Meia-Idade
Mixoma/cirurgia
Reoperação
Esternotomia/métodos
Fatores de Tempo
Tomógrafos Computadorizados
Resultado do Tratamento
[Pt] Tipo de publicação:CASE REPORTS
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170925
[Lr] Data última revisão:
170925
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170824
[St] Status:MEDLINE


  7 / 5938 MEDLINE  
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[PMID]:28690294
[Au] Autor:Song G; Liu J; Guo B; Sun F; Ren W; Li F; Huang W
[Ad] Endereço:Department of Ultrasound, Shengjing Hospital of China Medical University.
[Ti] Título:Unusual Coronary Sinus Tumor in a Pregnant Woman.
[So] Source:Int Heart J;58(4):633-636, 2017 Aug 03.
[Is] ISSN:1349-3299
[Cp] País de publicação:Japan
[La] Idioma:eng
[Ab] Resumo:Primary coronary sinus tumors are extremely rare. Herein, we present a case of a pregnant woman with a primary myxoma in the coronary sinus (CS), which was diagnosed by echocardiography and computed tomography. We reviewed the literature and found two other primary CS tumors. We summarized the gender, ages, symptoms, diagnostic methods, associated anomalies, treatments, histologic findings, and outcomes of the 3 cases. Dyspnea was a common symptom of all 3 patients. Diagnostic methods included echocardiography, computed tomography, magnetic resonance imaging, and coronary angiography. Associated anomalies included coronary artery fistulas, coronary sinus orifice atresia with persistent left superior vena cava, intra-cardiac invasion, and pericardial effusion. The 3 histologic types of primary CS tumor were haemangioma, lymphoma, and myxoma. The 3 patients received proper treatment and had good therapeutic outcomes.
[Mh] Termos MeSH primário: Seio Coronário
Mixoma/diagnóstico
Complicações Neoplásicas na Gravidez
Neoplasias Vasculares/diagnóstico
[Mh] Termos MeSH secundário: Adulto
Procedimentos Cirúrgicos Cardíacos/métodos
Angiografia Coronária
Diagnóstico Diferencial
Ecocardiografia
Feminino
Seres Humanos
Mixoma/cirurgia
Gravidez
Tomografia Computadorizada por Raios X
Neoplasias Vasculares/cirurgia
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE; REVIEW
[Em] Mês de entrada:1708
[Cu] Atualização por classe:170810
[Lr] Data última revisão:
170810
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170711
[St] Status:MEDLINE
[do] DOI:10.1536/ihj.16-383


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[PMID]:28642131
[Au] Autor:Zhang J; Wang C; Xu H
[Ad] Endereço:Department of Oncology, Huaihe Hospital of Henan University, Kaifeng, 475000, China. Electronic address: jingzhanggvit@126.com.
[Ti] Título:miR-217 suppresses proliferation and promotes apoptosis in cardiac myxoma by targeting Interleukin-6.
[So] Source:Biochem Biophys Res Commun;490(3):713-718, 2017 Aug 26.
[Is] ISSN:1090-2104
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Cardiac myxoma (CM) is a prevalent primary cardiac tumor. miR-217 plays a vital role in tumorigenesis of various cancers, however, its role and underlying molecular mechanism in human CM remain poorly understood. Here, we reported that the expression of miR-217 was downregulated in CM tissues and inversely correlated with the expression of Interleukin-6 (IL-6) mRNA. Gain-of-function analysis indicated that overexpression of miR-217 inhibited the proliferation and promoted the apoptosis of the primary CM cells. Bioinformatics analysis showed that IL-6 was a direct target gene of miR-217, which is confirmed by the dual luciferase assays. Moreover, downregulation of IL-6 by small interference RNA (siRNA) mimicked the tumor-suppressive effects of miR-217 in CM. Furthermore, rescue experiments pointed out that restoration of IL-6 expression abrogated the anti-proliferative and pro-apoptotic effect induced by miR-217 overexpression in CM cells. Taken together, we validated that miR-217 could act as a tumor suppressor in CM by directly targeting 3'UTR of IL-6 gene, indicating that manipulation of miR-217 may be a potential therapeutic strategy for CM patients.
[Mh] Termos MeSH primário: Regulação Neoplásica da Expressão Gênica
Neoplasias Cardíacas/genética
Interleucina-6/genética
MicroRNAs/genética
Miocárdio/patologia
Mixoma/genética
[Mh] Termos MeSH secundário: Apoptose
Proliferação Celular
Neoplasias Cardíacas/patologia
Seres Humanos
Miocárdio/metabolismo
Mixoma/patologia
Células Tumorais Cultivadas
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (IL6 protein, human); 0 (Interleukin-6); 0 (MIRN217 microRNA, human); 0 (MicroRNAs)
[Em] Mês de entrada:1708
[Cu] Atualização por classe:170811
[Lr] Data última revisão:
170811
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170624
[St] Status:MEDLINE


  9 / 5938 MEDLINE  
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[PMID]:28633254
[Au] Autor:Husso A; Savola J; Gunn J
[Ad] Endereço:Department of Cardiothoracic Surgery, Heart Center, Turku University Hospital, Turku, Finland. Electronic address: annastiina.husso@tyks.fi.
[Ti] Título:Successful Surgical Treatment of an Aggressive Pelvic Angiomyxoma With Intracardiac Extension.
[So] Source:Ann Thorac Surg;104(1):e23-e25, 2017 Jul.
[Is] ISSN:1552-6259
[Cp] País de publicação:Netherlands
[La] Idioma:eng
[Ab] Resumo:We present a case of an intravenous tumor with extension into the right atrium and right ventricle of the heart. Pelvic angiomyxoma is a rare benign tumor, which in this case carried a significant operative risk due to its extension. The patient initially presented with suspected caval and intracardiac thrombus, but unsuccessful treatment led to further investigations. The tumor was extensively dissected from the right atrium, suprarenal vena cava, and left iliac vein on cardiopulmonary bypass and deep hypothermic circulatory arrest. Affected gynecological organs were removed. The patient recovered uneventfully and received hormonal therapy postoperatively.
[Mh] Termos MeSH primário: Procedimentos Cirúrgicos Cardíacos/métodos
Neoplasias Cardíacas/cirurgia
Mixoma/cirurgia
Neoplasias Pélvicas/cirurgia
[Mh] Termos MeSH secundário: Parada Circulatória Induzida por Hipotermia Profunda
Feminino
Átrios do Coração
Neoplasias Cardíacas/diagnóstico
Seres Humanos
Meia-Idade
Mixoma/diagnóstico
Invasividade Neoplásica
Neoplasias Pélvicas/diagnóstico
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE; VIDEO-AUDIO MEDIA
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170901
[Lr] Data última revisão:
170901
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:170622
[St] Status:MEDLINE


  10 / 5938 MEDLINE  
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[PMID]:28549450
[Au] Autor:Xu J; Yang Q; Li J; Zheng X
[Ad] Endereço:Intensive Care Unit, The First Affiliated Hospital, College of Medicine, Zhejiang University, 79 Qingchun Road, Hangzhou, 310003, People's Republic of China.
[Ti] Título:The left atrial bacterial vegetative mass due to Corynebacterium striatum as a presentation of myxoma: a case report.
[So] Source:BMC Infect Dis;17(1):368, 2017 May 26.
[Is] ISSN:1471-2334
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Corynebacterium striatum is a member of the non-diphtherial corynebacteria, which are ubiquitous in nature and generally colonize the skin and mucous membranes of humans. Rarely, it causes infective endocarditis (IE). We report a case of rare left atrial bacterial vegetative mass due to C. striatum masquerading as a myxoma identified through a tortuous diagnostic process, and present a brief review of the relevant literature. CASE PRESENTATION: We present a case of 63-year-old man who presented with progressively worsening dyspnea on exertion and lower leg edema, and was diagnosed with heart failure. Transesophageal echocardiography (TEE) revealed that the left atrium was filled with a 2.7 cm × 2.6 cm mass. The patient, who had no signs of infection or related risk factors, was suspected of having a left atrial myxoma clinically. After excising the mass, the histopathology suggested thrombus with no myxocytes. Postoperatively, a fever appeared and C. striatum was isolated from the blood cultures. Although antibiotics were used, the symptoms of heart failure worsened gradually and echocardiography revealed valve vegetation. The patient underwent a second operation because of IE. Surprisingly, the mass was confirmed to be a bacterial vegetation due to C. striatum based on Gram staining at a 1000× magnification, although this was not noted on routine pathological examination of the two surgical specimens. CONCLUSIONS: Physicians should be aware of Corynebacterium in blood cultures, which cannot simply be assumed to be a contaminant. A diagnosis of IE should be suspected, particularly in high-risk patients or those with an unexplained fever. Our patient had IE due to C. striatum with no risk factors. This case supports the diagnosis of IE using a combination of pathology and etiology.
[Mh] Termos MeSH primário: Infecções por Corynebacterium/diagnóstico
Endocardite Bacteriana/diagnóstico
Átrios do Coração/microbiologia
[Mh] Termos MeSH secundário: Antibacterianos/uso terapêutico
Corynebacterium/patogenicidade
Infecções por Corynebacterium/tratamento farmacológico
Infecções por Corynebacterium/cirurgia
Diagnóstico Diferencial
Ecocardiografia
Endocardite/diagnóstico
Endocardite Bacteriana/tratamento farmacológico
Endocardite Bacteriana/cirurgia
Átrios do Coração/patologia
Insuficiência Cardíaca/diagnóstico
Neoplasias Cardíacas/diagnóstico
Seres Humanos
Masculino
Meia-Idade
Mixoma/diagnóstico
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Anti-Bacterial Agents)
[Em] Mês de entrada:1708
[Cu] Atualização por classe:170818
[Lr] Data última revisão:
170818
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170528
[St] Status:MEDLINE
[do] DOI:10.1186/s12879-017-2468-8



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