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[PMID]:28505003
[Au] Autor:Schneider N; Strauss DC; Smith MJ; Miah AB; Zaidi S; Benson C; van Houdt WJ; Jones RL; Hayes AJ; Fisher C; Thway K
[Ad] Endereço:Sarcoma Unit, Royal Marsden Hospital, London, UK.
[Ti] Título:The Adequacy of Core Biopsy in the Assessment of Smooth Muscle Neoplasms of Soft Tissues: Implications for Treatment and Prognosis.
[So] Source:Am J Surg Pathol;41(7):923-931, 2017 Jul.
[Is] ISSN:1532-0979
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:The grading of soft tissue sarcomas is one of the most important prognostic factors and determines patient management. Although grading of most adult-type soft tissue sarcomas on biopsies correlates highly with the final grading on the excision specimen, it appears less reliable for tumors of smooth muscle. We assessed the pathologic findings for smooth muscle neoplasms diagnosed by core biopsy at our tertiary sarcoma center, and compared them with those in the subsequent excision specimens. A total of 100 patients with leiomyosarcoma first diagnosed on core biopsy and with a subsequent excision were identified and the accuracy of the biopsy grade determined by comparison with the excision grade. Differences in other salient histologic parameters were also noted. A grade difference between biopsy and excision specimens of leiomyosarcomas was found in 68% of cases, with all these cases showing an increase in grade from biopsy to excision specimen. Of the 3 parameters used for grading using the French Federation of Cancer Centers Sarcoma Group Grading System (FNCLCC), necrosis was the score that most commonly differed between biopsy and excision specimen (55%), closely followed by the mitotic count (51%). The grading of soft tissue smooth muscle tumor biopsies has a lower accuracy compared with other adult soft tissue sarcomas and should therefore be taken with caution, particularly as this may be an underrepresentation of the true tumor grade.
[Mh] Termos MeSH primário: Leiomiossarcoma/patologia
Tumor de Músculo Liso/patologia
Neoplasias de Tecidos Moles/patologia
[Mh] Termos MeSH secundário: Biópsia com Agulha de Grande Calibre
Feminino
Seres Humanos
Masculino
Meia-Idade
Gradação de Tumores
[Pt] Tipo de publicação:EVALUATION STUDIES; JOURNAL ARTICLE
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170913
[Lr] Data última revisão:
170913
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170516
[St] Status:MEDLINE
[do] DOI:10.1097/PAS.0000000000000867


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[PMID]:28340268
[Au] Autor:Cao HY; Yang S; Wang S; Deng LY; Lou JY
[Ad] Endereço:Department of Gynecology and Obstetrics, West China Second University Hospital, Sichuan University, Chengdu, Sichuan Province, China.
[Ti] Título:Is differential expression of p16INK4a based on the classification of uterine smooth muscle tumors associated with a different prognosis? A meta-analysis.
[So] Source:Genet Mol Res;16(1), 2017 Mar 22.
[Is] ISSN:1676-5680
[Cp] País de publicação:Brazil
[La] Idioma:eng
[Ab] Resumo:We conducted a meta-analysis to examine p16INK4a expression in uterine smooth muscle tumors (USMTs). Although the prognostic value of tumor suppressor p16INK4a has been elucidated in a variety of cancers and precancerous lesions, its role in USMTs is not well established. We searched PubMed, Web of Science, and Embase for publication son p16INK4a expression in USMTs. Strict inclusion and exclusion criteria were imposed. Risk ratios (RRs) with 95% confidence intervals (95%CIs) were calculated to assess the strength of association. Publication bias was estimated using funnel plots and the Egger's regression test. Twelve eligible studies comprising 661 patients were included. Compared with leiomyoma (LM), the figures for the strength of association were as follows: LM variants (RR = 1.53, 95%CI = 1.03-2.27, P = 0.036, random effect); leiomyosarcoma (LMS) (RR = 3.20, 95%CI = 1.68-6.12, P < 0.001, random effect); and smooth muscle tumors of uncertain malignant potential (STUMP) (RR = 2.90, 95%CI = 1.17-7.21, P = 0.022, random effect). p16INK4a expression was significantly higher in LMS than in LM variants (RR = 3.74, 95%CI = 1.96-7.13, P < 0.001, random effect) or STUMP (RR = 1.67, 95%CI = 1.26-2.23, P < 0.001, fixed effect). There was a significant correlation between overexpressed p16INK4a and recurrence rates of USMTs (RR = 1.85, 95%CI = 1.11-3.10, P = 0.019, fixed effect). p16INK4a over expression is a potential biomarker for diagnosing problematic USMTs and it might indicate a worse prognosis. However, there is currently insufficient evidence to assess the prognostic value of p16INK4a in USMTs.
[Mh] Termos MeSH primário: Inibidor p16 de Quinase Dependente de Ciclina/biossíntese
Leiomioma/metabolismo
Leiomiossarcoma/metabolismo
Tumor de Músculo Liso/metabolismo
Neoplasias Uterinas/metabolismo
[Mh] Termos MeSH secundário: Biomarcadores Tumorais/genética
Biomarcadores Tumorais/metabolismo
Inibidor p16 de Quinase Dependente de Ciclina/genética
Feminino
Genes p16
Predisposição Genética para Doença
Seres Humanos
Leiomioma/genética
Leiomiossarcoma/genética
Recidiva Local de Neoplasia/genética
Recidiva Local de Neoplasia/metabolismo
Prognóstico
Tumor de Músculo Liso/genética
Neoplasias Uterinas/genética
[Pt] Tipo de publicação:JOURNAL ARTICLE; META-ANALYSIS
[Nm] Nome de substância:
0 (Biomarkers, Tumor); 0 (Cyclin-Dependent Kinase Inhibitor p16); 0 (P16 protein, human)
[Em] Mês de entrada:1704
[Cu] Atualização por classe:170426
[Lr] Data última revisão:
170426
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170325
[St] Status:MEDLINE
[do] DOI:10.4238/gmr16019481


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[PMID]:28221693
[Au] Autor:Yooprasert S; Thanapirom K; Treeprasertsuk S; Kullavanijaya P; Komolmit P
[Ad] Endereço:Divisions of Gastroenterology, Department of Medicine, Faculty of Medicine, Chulalongkorn University and King Chulalongkorn Memorial Hospital, Thai Red Cross Society, Bangkok, Thailand.
[Ti] Título:Hepatobiliary and Pancreatic: Epstein-Barr virus-associated smooth muscle tumors: Unusual cause of hepatic mass in AIDS patient.
[So] Source:J Gastroenterol Hepatol;32(2):293, 2017 Feb.
[Is] ISSN:1440-1746
[Cp] País de publicação:Australia
[La] Idioma:eng
[Mh] Termos MeSH primário: Síndrome de Imunodeficiência Adquirida/complicações
Herpesvirus Humano 4/patogenicidade
Neoplasias Hepáticas/etiologia
Tumor de Músculo Liso/etiologia
[Mh] Termos MeSH secundário: Adulto
Herpesvirus Humano 4/genética
Herpesvirus Humano 4/isolamento & purificação
Seres Humanos
Hospedeiro Imunocomprometido
Neoplasias Hepáticas/diagnóstico por imagem
Neoplasias Hepáticas/terapia
Neoplasias Hepáticas/virologia
Imagem por Ressonância Magnética
Masculino
RNA Viral/análise
Tumor de Músculo Liso/diagnóstico por imagem
Tumor de Músculo Liso/terapia
Tumor de Músculo Liso/virologia
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Nm] Nome de substância:
0 (RNA, Viral)
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170919
[Lr] Data última revisão:
170919
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170222
[St] Status:MEDLINE
[do] DOI:10.1111/jgh.13539


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[PMID]:28004108
[Au] Autor:Conconi D; Chiappa V; Perego P; Redaelli S; Bovo G; Lavitrano M; Milani R; Dalprà L; Lissoni AA
[Ad] Endereço:School of Medicine and Surgery, University of Milano-Bicocca, I-20900 Monza, Italy.
[Ti] Título:Potential role of BCL2 in the recurrence of uterine smooth muscle tumors of uncertain malignant potential.
[So] Source:Oncol Rep;37(1):41-47, 2017 Jan.
[Is] ISSN:1791-2431
[Cp] País de publicação:Greece
[La] Idioma:eng
[Ab] Resumo:Uterine smooth muscle tumors are the most common female genital tract neoplasms. While leiomyosarcoma has been studied at length, smooth muscle tumors of uncertain malignant potential (STUMPs) still have ambiguous and unresolved issues, with a risk of relapse and evolution largely undefined. We performed an array comparative genomic hybridization analysis on a primitive STUMP and its local recurrence, histologically diagnosed as undifferentiated sarcoma. To the best of our knowledge, our report is the first genomic study on primitive STUMPs and the different relapsed tumors. The results showed few copy number alterations shared between both samples and the high heterogeneity in the STUMP was apparently lost in the sarcoma. Surprisingly the STUMP presented an amplification of the BCL2 gene, not observed in the relapsed tumor. Additionally, fluorescence in situ hybridization and immunohistochemical staining were performed to confirm BCL2 amplification and expression in these samples and in two other cases of primitive STUMPs and their corresponding relapsed tumors. The presence of BCL2 in multiple copies and expression in the two primitive STUMPs and two relapsed tumors was confirmed. The marked amplification of the BCL2 gene present in the primitive STUMP and the multiple copies also observed in other cases, suggest its potential role as a marker of STUMP malignant potential and recurrence.
[Mh] Termos MeSH primário: Proteínas Proto-Oncogênicas c-bcl-2/genética
Tumor de Músculo Liso/patologia
Neoplasias Uterinas/patologia
[Mh] Termos MeSH secundário: Adulto
Biomarcadores Tumorais/genética
Biomarcadores Tumorais/metabolismo
Hibridização Genômica Comparativa
Feminino
Seres Humanos
Hibridização in Situ Fluorescente
Leiomioma/genética
Leiomioma/patologia
Meia-Idade
Recidiva Local de Neoplasia/genética
Recidiva Local de Neoplasia/patologia
Proteínas Proto-Oncogênicas c-bcl-2/metabolismo
Tumor de Músculo Liso/genética
Neoplasias Uterinas/genética
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Biomarkers, Tumor); 0 (Proto-Oncogene Proteins c-bcl-2)
[Em] Mês de entrada:1703
[Cu] Atualização por classe:170403
[Lr] Data última revisão:
170403
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161223
[St] Status:MEDLINE
[do] DOI:10.3892/or.2016.5274


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[PMID]:27864989
[Au] Autor:Chow KL; Tse KY; Cheung CL; Wong KW; Cheung AN; Wong RW; Chan AN; Yuen NW; Ngan HY; Ip PP
[Ad] Endereço:Pathology, The University of Hong Kong, Queen Mary Hospital, Hong Kong, Hong Kong.
[Ti] Título:The mitosis-specific marker phosphohistone-H3 (PHH3) is an independent prognosticator in uterine smooth muscle tumours: an outcome-based study.
[So] Source:Histopathology;70(5):746-755, 2017 Apr.
[Is] ISSN:1365-2559
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:AIMS: Accurate mitosis counting, which is important in the diagnosis of uterine smooth muscle tumours (USMTs), is often difficult and subjective. The mitosis-specific immunohistochemical marker phosphohistone-H3 (PHH3) has been shown to be diagnostically useful, but its expression, in relation to outcome, has not been thoroughly investigated. The aim of this study is to evaluate PHH3 as a diagnostic and prognostic marker in USMTs. METHODS AND RESULTS: PHH3 expression was evaluated in 55 leiomyosarcomas (LMSs), 26 smooth muscle tumours of uncertain malignant potential (STUMPs), 18 leiomyomas with bizarre nuclei (LBN), and 12 leiomyomas (LMs). Scores were expressed as counts per 10 high-power fields (HPFs). Median follow-up durations of patients with LMS, STUMP, LBN and LM were, respectively, 39, 78, 65.5 and 49.5 months. Twenty-eight patients with LMSs (50.9%) died, and two (7.7%) patients with STUMPs experienced recurrence. The median PHH3 scores for LMSs were significantly higher than those for other categories of tumour. A score of ≥29/10 HPFs was also independently associated with a poor outcome. To test whether the PHH3 score could distinguish between benign USMTs with atypical histology and those that were clinically malignant, two biological groups were further delineated. Patients in group 1 (18 LBNs and 24 STUMPs) all had an uneventful outcome, whereas patients in group 2 (two recurrent STUMPs and 32 LMSs) all had a recurrence or tumour-related death. Median PHH3 scores for the two groups were, respectively, 2/10 HPFs and 27/10 HPFs. A PHH3 score of ≥7/10 HPFs was highly associated with malignancy. CONCLUSION: PHH3 is useful in evaluation of the biological behaviour of USMTs, and may serve as a prognostic indicator for LMSs.
[Mh] Termos MeSH primário: Biomarcadores Tumorais/análise
Histonas/biossíntese
Tumor de Músculo Liso/patologia
Neoplasias Uterinas/patologia
[Mh] Termos MeSH secundário: Adulto
Idoso
Idoso de 80 Anos ou mais
Área Sob a Curva
Feminino
Histonas/análise
Seres Humanos
Estimativa de Kaplan-Meier
Meia-Idade
Mitose
Recidiva Local de Neoplasia/patologia
Prognóstico
Modelos de Riscos Proporcionais
Curva ROC
Sensibilidade e Especificidade
Tumor de Músculo Liso/mortalidade
Neoplasias Uterinas/mortalidade
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Biomarkers, Tumor); 0 (Histones)
[Em] Mês de entrada:1708
[Cu] Atualização por classe:170818
[Lr] Data última revisão:
170818
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161120
[St] Status:MEDLINE
[do] DOI:10.1111/his.13124


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[PMID]:27817933
[Au] Autor:Raspagliesi F; Maltese G; Bogani G; Fucà G; Lepori S; De Iaco P; Perrone M; Scambia G; Cormio G; Bogliolo S; Bergamini A; Bifulco G; Casali PG; Lorusso D
[Ad] Endereço:Fondazione IRCCS Istituto Nazionale dei Tumori, Department of Gynecologic Oncology, Milan, Italy.
[Ti] Título:Morcellation worsens survival outcomes in patients with undiagnosed uterine leiomyosarcomas: A retrospective MITO group study.
[So] Source:Gynecol Oncol;144(1):90-95, 2017 Jan.
[Is] ISSN:1095-6859
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:OBJECTIVE: To investigate the impact of morcellation on survival outcomes of patients affected by undiagnosed uterine sarcoma. METHODS: This is a retrospective study performed in 8 referral centers of MITO group. Data of women undergoing morcellation for apparent benign uterine myomas who were ultimately diagnosed with stage I uterine sarcoma on final pathology were compared with data of women who did not undergo morcellation. Uterine sarcoma included: leiomyosarcomas (LMS), smooth muscle tumors of uncertain malignant potential (STUMP), low-grade endometrial stromal sarcomas (LG-ESS) and undifferentiated uterine sarcomas (UUS). Two-year survival outcomes were evaluated using Kaplan-Meir and Cox models. RESULTS: Overall 125 patients were identified: 31(24.8%), 21(16.8%) and 73(58.4%) patients had power morcellation during laparoscopy, non power morcellation during open surgery and non morcellation during open procedures, respectively. Considering patients affected by LMS, morcellation did not correlated with disease-free survival. However, patients undergoing either morcellation or power morcellation experienced a 3-fold increase risk of death in comparison to patients who had not morcellation (p=0.02). A trend towards an increase of recurrence was observed for patients undergoing morcellation for STUMP (HR 7.7, p=0.09); while no differences in survival outcomes were observed for patients with LG-ESS and UUS. CONCLUSIONS: Our data suggest that morcellation increase the risk of death in patients affected by undiagnosed LMS. Further prospective studies are warranted in order to assess the risk to benefit ratio of power morcellator utilization in patients with apparent benign uterine myomas.
[Mh] Termos MeSH primário: Leiomioma/cirurgia
Leiomiossarcoma/cirurgia
Morcelação/efeitos adversos
Tumor de Músculo Liso/cirurgia
Neoplasias Uterinas/patologia
Neoplasias Uterinas/cirurgia
[Mh] Termos MeSH secundário: Adulto
Intervalo Livre de Doença
Feminino
Seres Humanos
Laparoscopia/métodos
Leiomioma/diagnóstico
Leiomioma/patologia
Leiomiossarcoma/diagnóstico
Leiomiossarcoma/patologia
Meia-Idade
Morcelação/métodos
Estudos Retrospectivos
Tumor de Músculo Liso/diagnóstico
Tumor de Músculo Liso/patologia
Sobrevida
Neoplasias Uterinas/diagnóstico
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1705
[Cu] Atualização por classe:170530
[Lr] Data última revisão:
170530
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161108
[St] Status:MEDLINE


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[PMID]:27306954
[Au] Autor:Grumbine FL; DeParis SW; Vagefi MR; Bloomer M; Kersten RC
[Ad] Endereço:*Department of Ophthalmology, University of California, San Francisco, San Francisco, California; and †Department of Ophthalmology and Visual Sciences, University of Maryland School of Medicine, Baltimore, Maryland, U.S.A.
[Ti] Título:Lacrimal Sac Smooth Muscle Tumor of Uncertain Malignant Potential.
[So] Source:Ophthal Plast Reconstr Surg;33(3S Suppl 1):S29-S31, 2017 May/Jun.
[Is] ISSN:1537-2677
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:A 13-year-old male presented with recurrent left nasolacrimal duct obstruction following endoscopic dacryocystorhinostomy 4 years prior at an outside institution. The past medical history was significant for stage IV neuroblastoma, diagnosed at age 2, requiring surgical resection, induction chemotherapy, autologous bone marrow transplantation and radiation, currently in remission. Preoperative CT scan demonstrated a 2 cm ovoid mass centered in the left lacrimal fossa, consistent with dacryocystocele; however, a solid tumor could not be ruled out. Subsequent surgical exploration of the lacrimal sac revealed a friable, solid mass filling the lacrimal sac, and extending into the duct. The mass was grossly resected with preservation of the lacrimal drainage system and placement of indwelling silicone stents. Histopathology confirmed the diagnosis of smooth muscle tumor of uncertain malignant potential. The patient remained free of epiphora and showed no clinical or radiographic evidence of recurrence at 6 months of follow up.
[Mh] Termos MeSH primário: Neoplasias Oculares/diagnóstico
Doenças do Aparelho Lacrimal/diagnóstico
Ducto Nasolacrimal/diagnóstico por imagem
Tumor de Músculo Liso/diagnóstico
[Mh] Termos MeSH secundário: Adolescente
Biópsia
Terapia Combinada
Neoplasias Oculares/terapia
Seres Humanos
Doenças do Aparelho Lacrimal/terapia
Masculino
Tumor de Músculo Liso/terapia
Tomografia Computadorizada por Raios X
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170901
[Lr] Data última revisão:
170901
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160617
[St] Status:MEDLINE
[do] DOI:10.1097/IOP.0000000000000726


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[PMID]:27879303
[Au] Autor:Nayak DR; Ghanpur AD; Reddy AN; Sharma S
[Ad] Endereço:Department of Otolaryngology-Head and Neck Surgery, Kasturba Medical College, Manipal, Karnataka, India.
[Ti] Título:Smooth muscle tumour of uncertain malignant potential (SMTUMP) in the nasal cavity: an incidental finding.
[So] Source:BMJ Case Rep;2016, 2016 Nov 22.
[Is] ISSN:1757-790X
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Sino-nasal smooth muscle tumours of uncertain malignant potential (SMTUMP) are very rare neoplasms of mesenchymal origin with features in between a benign leiomyoma and a leiomyosarcoma. We report a rare case of SMTUMP in a 44-year-old woman, who presented with vague symptoms of pharyngitis. Nasal endoscopy revealed a smooth mass in left nasal cavity. Contrast-enhanced CT and MRI scans showed features likely to be inverted papilloma or olfactory neuroblastoma or meningioma. Excision was planned and intraoperatively, frozen section revealed a probable spindle cell lesion. Final histopathological report following immunohistochemistry (IHC) & immunofluoresence (IF) confirmed it to be a SMTUMP. This patient underwent complete resection via endoscopic KTP laser assisted, anterior skull base surgery with no recurrence on follow-up.
[Mh] Termos MeSH primário: Achados Incidentais
Cavidade Nasal
Neoplasias Nasais/diagnóstico
Tumor de Músculo Liso/diagnóstico
[Mh] Termos MeSH secundário: Adulto
Feminino
Seres Humanos
Neoplasias Nasais/complicações
Faringite/etiologia
Tumor de Músculo Liso/complicações
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Em] Mês de entrada:1703
[Cu] Atualização por classe:170303
[Lr] Data última revisão:
170303
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161124
[St] Status:MEDLINE


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[PMID]:27649950
[Au] Autor:Fernandez-Flores A; Monteagudo C
[Ad] Endereço:Department of Cellular Pathology, Hospital El Bierzo, Ponferrada, Spain. Electronic address: dermatopathonline@gmail.com.
[Ti] Título:Immunoexpression of p53 in cutaneous and subcutaneous leiomyosarcomas.
[So] Source:Ann Diagn Pathol;24:25-9, 2016 Oct.
[Is] ISSN:1532-8198
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:The diagnosis of malignancy in cutaneous and subcutaneous smooth muscle tumors is based on subtle criteria. Therefore, any ancillary technique useful in this differential diagnosis is always welcome. In this report, we study the immunoexpression of p53 in 19 malignant smooth muscle tumors of the skin (15 cutaneous leiomyosarcomas, 2 subcutaneous leiomyosarcomas, and 2 cutaneous metastases of leiomyosarcoma), as well as in 1 leiomyoma with cellular atypia, therefore complementing a previous study on p53 immunoexpression in leiomyomas of the skin. The p53 staining was positive in 12 (63.16%) of 19 leiomyosarcomas. Percentages of immunostaining in the positive cases varied from 2% to 95%. Ten (66.66%) of 15 cutaneous leiomyosarcomas were positive for p53, and in 4 of these cases, immunoexpression was demonstrated by more than 50% of the cells. Five (33.33%) cutaneous leiomyosarcomas did not show any expression of p53. Of the 2 subcutaneous leiomyosarcomas, one was negative for p53 and the other expressed the marker in 70% of the cells. The only atypical leiomyoma included in the study did not express p53. Of the 2 cutaneous metastases of leiomyosarcoma, one was negative and the other expressed p53 in 20% of the cells. The current study supports our previous conclusions that p53 immunoexpression in more than 1% of the cells in a cutaneous smooth muscle tumor is indicative of malignancy. However, we believe that additional studies on atypical leiomyoma are needed.
[Mh] Termos MeSH primário: Leiomiossarcoma/patologia
Neoplasias Cutâneas/patologia
Tumor de Músculo Liso/patologia
Proteína Supressora de Tumor p53/metabolismo
Neoplasias Uterinas/patologia
[Mh] Termos MeSH secundário: Adulto
Idoso
Idoso de 80 Anos ou mais
Diagnóstico Diferencial
Feminino
Seres Humanos
Imuno-Histoquímica/métodos
Leiomioma/diagnóstico
Leiomiossarcoma/diagnóstico
Masculino
Meia-Idade
Neoplasias Cutâneas/diagnóstico
Tumor de Músculo Liso/diagnóstico
Neoplasias Uterinas/diagnóstico
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (TP53 protein, human); 0 (Tumor Suppressor Protein p53)
[Em] Mês de entrada:1703
[Cu] Atualização por classe:170721
[Lr] Data última revisão:
170721
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160922
[St] Status:MEDLINE


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[PMID]:27641816
[Au] Autor:Ayadi L; Mallouli M; Kallel R; Charfi S; Triki M; Boudawara T; Gouiaa N
[Ad] Endereço:Laboratoire d'anatomie et de cytologie pathologique, CHU Habib Bourguiba, route El Ain Km 0.5, 3029 Sfax, Tunisie. Electronic address: ayadilobna@yahoo.fr.
[Ti] Título:[Rare tumor of the breast with indeterminate prognosis].
[Ti] Título:Tumeur rare du sein de pronostic indéterminé..
[So] Source:Ann Pathol;36(5):366-368, 2016 Oct.
[Is] ISSN:0242-6498
[Cp] País de publicação:France
[La] Idioma:fre
[Mh] Termos MeSH primário: Neoplasias da Mama/patologia
Tumor de Músculo Liso/patologia
[Mh] Termos MeSH secundário: Neoplasias da Mama/diagnóstico
Neoplasias da Mama/cirurgia
Diagnóstico Diferencial
Feminino
Seres Humanos
Mastectomia Segmentar
Mioepitelioma/diagnóstico
Neoplasias de Tecido Muscular/diagnóstico
Prognóstico
Tumor de Músculo Liso/diagnóstico
Tumor de Músculo Liso/cirurgia
Adulto Jovem
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171016
[Lr] Data última revisão:
171016
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160920
[St] Status:MEDLINE



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