Base de dados : MEDLINE
Pesquisa : C04.557.465.625 [Categoria DeCS]
Referências encontradas : 393 [refinar]
Mostrando: 1 .. 10   no formato [Detalhado]

página 1 de 40 ir para página                         

  1 / 393 MEDLINE  
              next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:28468165
[Au] Autor:Cantini A JE; Díaz López DM; Hernandez Florez EF
[Ad] Endereço:*Plastic Surgery Department from the San Jose Hospital, University Foundation of Health Sciences, Bogotá †Cancer Clinic of Norte de Santander, Colombian Association of Hematology, Cúcuta, Colombia.
[Ti] Título:Orbital Reconstruction in Neuroectodermal Tumor of the Orbit: Multimodal Treatment Approach.
[So] Source:J Craniofac Surg;28(3):781-784, 2017 May.
[Is] ISSN:1536-3732
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:INTRODUCTION: Primitive neuroectodermal tumors of peripheral origin are very rare, and orbital neuroectodermal tumors are even more uncommon. Only 25 patients with primary orbital involvement in the pediatric age group have been reported. METHODS: In this article, the authors describe their experience in the multimodality treatment approach to treat neuroectodermal tumor of the orbit. The authors also present a male patient 3-year old presenting with a neuroectodermal tumor of the right orbit causing rapidly progressive proptosis. The patient underwent an upper and lateral orbital marginotomy. The entire bone defect was reconstructed with a bone graft, allowing for the reconstruction of the floor and the lateral wall of the middle cranial fossa, the floor of the anterior cranial fossa, the upper and lateral orbital frame, and the right zygomatic bone. Over a period of 16 months, the patient was subjected to chemotherapy. RESULTS: In the postoperative period, a favorable evolution of the disease was observed, with growth in the reconstructed structures, good projection of the orbit and the eyeball, and stable results without tumor recurrence. CONCLUSIONS: The authors present the clinical analysis, surgical management, as well as the chemotherapy treatment established, with follow-ups at 1 and 2 and a half years. This experience shows the effectiveness of multimodality therapy in the treatment of rare tumors of difficult handling.
[Mh] Termos MeSH primário: Transplante Ósseo/métodos
Fossa Craniana Média/cirurgia
Tumores Neuroectodérmicos/cirurgia
Órbita/cirurgia
Neoplasias Orbitárias/cirurgia
Implante de Prótese/métodos
Procedimentos Cirúrgicos Reconstrutivos/métodos
[Mh] Termos MeSH secundário: Antineoplásicos/uso terapêutico
Pré-Escolar
Terapia Combinada
Seguimentos
Seres Humanos
Imagem por Ressonância Magnética
Masculino
Tumores Neuroectodérmicos/diagnóstico
Tumores Neuroectodérmicos/tratamento farmacológico
Neoplasias Orbitárias/diagnóstico
Neoplasias Orbitárias/tratamento farmacológico
Fatores de Tempo
Tomografia Computadorizada por Raios X
Zigoma/cirurgia
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Antineoplastic Agents)
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180209
[Lr] Data última revisão:
180209
[Sb] Subgrupo de revista:D
[Da] Data de entrada para processamento:170505
[St] Status:MEDLINE
[do] DOI:10.1097/SCS.0000000000003471


  2 / 393 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:28320420
[Au] Autor:Alyousef MJ; Alratroot JA; ElSharkawy T; Shawarby MA; Al Hamad MA; Hashem TM; Alsayyah A
[Ad] Endereço:Department of Pathology and Laboratory Medicine, King Fahd Hospital of University, College of Medicine, University of Dammam, Dammam, Saudi Arabia. malyousef@uod.edu.sa.
[Ti] Título:Malignant gastrointestinal neuroectodermal tumor: a case report and review of the literature.
[So] Source:Diagn Pathol;12(1):29, 2017 Mar 20.
[Is] ISSN:1746-1596
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Malignant gastrointestinal neuroectodermal tumor (GNET) is an extremely rare entity that was first described by Zambrano et al. in 2003 as "Clear cell sarcoma-like tumor of the gastrointestinal tract". It shares some of the histological features of clear cell sarcoma (CCS) but lacks the immunohistochemical reactivity for melanocytic markers. We report a case of GNET that was initially misdiagnosed as gastrointestinal stromal tumor (GIST). Recognizing this entity is important to avoid misdiagnosis. CASE PRESENTATION: A case of an 18-year-old male presented with a small intestinal tumor. Histologically it was characterized by polygonal cells arranged in pseudoalveolar pattern and situated in the muscularis propria. Scattered osteoclast-like multinucleated giant cells were also noted. The neoplastic cells were positive for S-100 protein and negative for HMB-45, Melan A, smooth muscle actin, desmin and CD117. EWSR1 gene rearrangement was detected by fluorescence in situ hybridization (FISH) analysis. The patient returned with recurrence after 36 months' management by surgical resection and died one year later. CONCLUSIONS: GNET can be mistaken histologically for other non-epithelial gastrointestinal tumors. Awareness of its existence and diagnostic criteria by the pathologist is necessary to avoid misdiagnosis, particularly as GIST, CCS or malignant peripheral nerve sheath tumor (MPNST).
[Mh] Termos MeSH primário: Tumores do Estroma Gastrointestinal/patologia
Neoplasias do Jejuno/patologia
Tumores Neuroectodérmicos/patologia
[Mh] Termos MeSH secundário: Adolescente
Biomarcadores Tumorais/análise
Biomarcadores Tumorais/genética
Biópsia
Proteínas de Ligação a Calmodulina/genética
Erros de Diagnóstico
Evolução Fatal
Tumores do Estroma Gastrointestinal/química
Tumores do Estroma Gastrointestinal/genética
Rearranjo Gênico
Seres Humanos
Imuno-Histoquímica
Hibridização in Situ Fluorescente
Neoplasias do Jejuno/química
Neoplasias do Jejuno/genética
Neoplasias do Jejuno/cirurgia
Masculino
Recidiva Local de Neoplasia
Tumores Neuroectodérmicos/química
Tumores Neuroectodérmicos/genética
Tumores Neuroectodérmicos/cirurgia
Valor Preditivo dos Testes
Proteína EWS de Ligação a RNA
Proteínas de Ligação a RNA/genética
Fatores de Tempo
Resultado do Tratamento
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE; REVIEW
[Nm] Nome de substância:
0 (Biomarkers, Tumor); 0 (Calmodulin-Binding Proteins); 0 (EWSR1 protein, human); 0 (RNA-Binding Protein EWS); 0 (RNA-Binding Proteins)
[Em] Mês de entrada:1703
[Cu] Atualização por classe:171116
[Lr] Data última revisão:
171116
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170322
[St] Status:MEDLINE
[do] DOI:10.1186/s13000-017-0620-9


  3 / 393 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
[PMID]:27764830
[Au] Autor:Subbiah V; Holmes O; Gowen K; Spritz D; Amini B; Wang WL; Schrock AB; Meric-Bernstam F; Zinner R; Piha-Paul S; Zarzour M; Elvin JA; Erlich RL; Stockman DL; Vergilio JA; Suh JH; Stephens PJ; Miller V; Ross JS; Ali SM
[Ad] Endereço:The University of Texas MD Anderson Cancer Center, Houston, Tex., USA.
[Ti] Título:Activity of c-Met/ALK Inhibitor Crizotinib and Multi-Kinase VEGF Inhibitor Pazopanib in Metastatic Gastrointestinal Neuroectodermal Tumor Harboring EWSR1-CREB1 Fusion.
[So] Source:Oncology;91(6):348-353, 2016.
[Is] ISSN:1423-0232
[Cp] País de publicação:Switzerland
[La] Idioma:eng
[Ab] Resumo:Malignant gastrointestinal neuroectodermal tumor (GNET) is an aggressive rare tumor, primarily occurring in young adults with frequent local-regional metastases and recurrence after local control. The tumor is characterized by the presence of EWSR1-ATF1 or EWSR1-CREB1 and immunohistochemical positivity for S-100 protein without melanocytic marker positivity. Due to poor responses to standard sarcoma regimens, GNET has a poor prognosis, and development of effective systemic therapy is desperately needed to treat these patients. Herein, we present a patient with a small bowel GNET who experienced recurrent hepatic and skeletal metastases after a primary resection. Comprehensive genomic profiling (CGP) in the course of clinical care with DNA and RNA sequencing demonstrated the presence of an exon 7 to exon 6 EWSR1-CREB1 fusion in the context of a diploid genome with no other genomic alterations. In a clinical trial, the patient received a combination of 250 mg crizotinib with 600 mg pazopanib quaque die and achieved partial response and durable clinical benefit for over 2.8 years, and with minimal toxicity from therapy. Using a CGP database of over 50,000 samples, we identified 11 additional cases that harbor EWSR1-CREB1 and report clinicopathologic characteristics, as these patients may also benefit from such a regimen.
[Mh] Termos MeSH primário: Protocolos de Quimioterapia Combinada Antineoplásica/uso terapêutico
Neoplasias Ósseas/tratamento farmacológico
Neoplasias Intestinais/tratamento farmacológico
Neoplasias Intestinais/genética
Neoplasias Hepáticas/tratamento farmacológico
Tumores Neuroectodérmicos/tratamento farmacológico
Tumores Neuroectodérmicos/genética
Proteínas de Fusão Oncogênicas/genética
[Mh] Termos MeSH secundário: Adolescente
Adulto
Neoplasias Ósseas/secundário
Feminino
Seres Humanos
Neoplasias Intestinais/patologia
Neoplasias Hepáticas/secundário
Masculino
Meia-Idade
Tumores Neuroectodérmicos/secundário
Proteínas Proto-Oncogênicas c-met/antagonistas & inibidores
Pirazóis/administração & dosagem
Piridinas/administração & dosagem
Pirimidinas/administração & dosagem
Receptores Proteína Tirosina Quinases/antagonistas & inibidores
Critérios de Avaliação de Resposta em Tumores Sólidos
Sulfonamidas/administração & dosagem
Fator A de Crescimento do Endotélio Vascular/antagonistas & inibidores
Adulto Jovem
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Nm] Nome de substância:
0 (EWSR1-CREB1 fusion protein, human); 0 (Oncogene Proteins, Fusion); 0 (Pyrazoles); 0 (Pyridines); 0 (Pyrimidines); 0 (Sulfonamides); 0 (Vascular Endothelial Growth Factor A); 53AH36668S (crizotinib); 7RN5DR86CK (pazopanib); EC 2.7.10.1 (Proto-Oncogene Proteins c-met); EC 2.7.10.1 (Receptor Protein-Tyrosine Kinases); EC 2.7.10.1 (anaplastic lymphoma kinase)
[Em] Mês de entrada:1701
[Cu] Atualização por classe:171021
[Lr] Data última revisão:
171021
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161021
[St] Status:MEDLINE


  4 / 393 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
[PMID]:27323560
[Au] Autor:Bilqees F; Samina K; Mohammad T; Khaleeq-uz-Zamaan
[Ti] Título:MORPHOLOGICAL PATTERN AND FREQUENCY OF CENTRAL NERVOUS SYSTEM TUMOURS IN CHILDREN.
[So] Source:J Ayub Med Coll Abbottabad;28(1):44-6, 2016 Jan-Mar.
[Is] ISSN:1025-9589
[Cp] País de publicação:Pakistan
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Recent studies, including a comprehensive study by National Cancer Institute, have shown that a significant increase in the incidence of childhood brain tumours makes them the most common paediatric tumour. The objectives of this study were to determine the frequency of central nervous system tumours in paediatric age group (0-12 years), and to segregate various morphologic types according to WHO classification. METHODS: The study included consecutive cases of central nervous system tumours diagnosed in children in the histopathology department at Federal Government Polyclinic, PGMI, Islamabad, during a period of 4.8 years (Jan 2009-Aug 2013). The initial histopathological evaluation of these lesions was performed on H&E stained sections of paraffin embedded tissues. Special stains and immunohistochemistry were performed whenever indicated. RESULTS: Out of 75 cases, 34 (45.3%) were astrocytic tumours, including 16 (47.1%) Pilocytic astrocytomas (WHO Grade-I), 1 (2.9%) diffuse fibrillary astrocytoma (WHO Grade-II), 1 (2.9%) anaplastic astrocytoma (WHO Grade-III) and 16(47.1%) glioblastoma multiforme (WHO Grade-IV); 18 (24%) were embryonal tumours including 17 (94.4%) medulloblastoma (WHO Grade-IV) and 1 (5.6%) neuroblastoma (WHO Grade IV); 10 (13.3%) were craniopharyngiomas (WHO Grade-I) and 5 (6.7%) were ependymal tumours including 1 (20%) myxopapillary ependymoma (WHO Grade-I) and 4 (80%) ependymomas (WHO Grade-II). Miscellaneous entities included 3 (4%) choroid plexus tumours; 1 (2%) anaplastic oligodendroglioma (WHO Grade-III); 1 (2%) atypical meningioma (WHO Grade-II); 1 (2%) schwannoma (WHO Grade-I); 1 (2%) neurofibroma (WHO Grade-I) and 1 (2%) lipoma (WHO Grade-I). CONCLUSION: Astrocytic tumours are the most common central nervous system tumours in paediatric age group and high grade lesions (WHO Grade-IV) constitute the largest category (45.3%).
[Mh] Termos MeSH primário: Neoplasias do Sistema Nervoso Central/epidemiologia
Neoplasias do Sistema Nervoso Central/patologia
[Mh] Termos MeSH secundário: Criança
Pré-Escolar
Feminino
Seres Humanos
Imuno-Histoquímica
Incidência
Lactente
Lipoma/epidemiologia
Lipoma/patologia
Masculino
Meningioma/epidemiologia
Meningioma/patologia
Tumores Neuroectodérmicos/patologia
Paquistão/epidemiologia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1608
[Cu] Atualização por classe:160621
[Lr] Data última revisão:
160621
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160622
[St] Status:MEDLINE


  5 / 393 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:26972854
[Au] Autor:Burki TK
[Ti] Título:Patient.
[So] Source:Lancet Oncol;17(3):283, 2016 Mar.
[Is] ISSN:1474-5488
[Cp] País de publicação:England
[La] Idioma:eng
[Mh] Termos MeSH primário: Assistência à Saúde
Narração
Tumores Neuroectodérmicos/diagnóstico
Tumores Neuroectodérmicos/terapia
Neoplasias da Traqueia/diagnóstico
Neoplasias da Traqueia/terapia
[Mh] Termos MeSH secundário: Colômbia
Feminino
Seres Humanos
Adulto Jovem
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Em] Mês de entrada:1608
[Cu] Atualização por classe:160314
[Lr] Data última revisão:
160314
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160315
[St] Status:MEDLINE


  6 / 393 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:26919435
[Au] Autor:Sturm D; Orr BA; Toprak UH; Hovestadt V; Jones DTW; Capper D; Sill M; Buchhalter I; Northcott PA; Leis I; Ryzhova M; Koelsche C; Pfaff E; Allen SJ; Balasubramanian G; Worst BC; Pajtler KW; Brabetz S; Johann PD; Sahm F; Reimand J; Mackay A; Carvalho DM; Remke M; Phillips JJ; Perry A; Cowdrey C; Drissi R; Fouladi M; Giangaspero F; Lastowska M; Grajkowska W; Scheurlen W; Pietsch T; Hagel C; Gojo J; Lötsch D; Berger W; Slavc I; Haberler C; Jouvet A; Holm S; Hofer S; Prinz M; Keohane C; Fried I; Mawrin C; Scheie D; Mobley BC; Schniederjan MJ
[Ad] Endereço:Division of Pediatric Neurooncology, German Cancer Research Center (DKFZ) and German Cancer Consortium (DKTK), 69120 Heidelberg, Germany.
[Ti] Título:New Brain Tumor Entities Emerge from Molecular Classification of CNS-PNETs.
[So] Source:Cell;164(5):1060-1072, 2016 Feb 25.
[Is] ISSN:1097-4172
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Primitive neuroectodermal tumors of the central nervous system (CNS-PNETs) are highly aggressive, poorly differentiated embryonal tumors occurring predominantly in young children but also affecting adolescents and adults. Herein, we demonstrate that a significant proportion of institutionally diagnosed CNS-PNETs display molecular profiles indistinguishable from those of various other well-defined CNS tumor entities, facilitating diagnosis and appropriate therapy for patients with these tumors. From the remaining fraction of CNS-PNETs, we identify four new CNS tumor entities, each associated with a recurrent genetic alteration and distinct histopathological and clinical features. These new molecular entities, designated "CNS neuroblastoma with FOXR2 activation (CNS NB-FOXR2)," "CNS Ewing sarcoma family tumor with CIC alteration (CNS EFT-CIC)," "CNS high-grade neuroepithelial tumor with MN1 alteration (CNS HGNET-MN1)," and "CNS high-grade neuroepithelial tumor with BCOR alteration (CNS HGNET-BCOR)," will enable meaningful clinical trials and the development of therapeutic strategies for patients affected by poorly differentiated CNS tumors.
[Mh] Termos MeSH primário: Neoplasias do Sistema Nervoso Central/genética
Neoplasias do Sistema Nervoso Central/patologia
Metilação de DNA
Tumores Neuroectodérmicos/genética
Tumores Neuroectodérmicos/patologia
[Mh] Termos MeSH secundário: Sequência de Aminoácidos
Neoplasias do Sistema Nervoso Central/classificação
Neoplasias do Sistema Nervoso Central/diagnóstico
Criança
Fatores de Transcrição Forkhead/genética
Perfilação da Expressão Gênica
Regulação Neoplásica da Expressão Gênica
Seres Humanos
Dados de Sequência Molecular
Tumores Neuroectodérmicos/classificação
Tumores Neuroectodérmicos/diagnóstico
Proteínas Proto-Oncogênicas/química
Proteínas Proto-Oncogênicas/genética
Proteínas Repressoras/química
Proteínas Repressoras/genética
Transdução de Sinais
Proteínas Supressoras de Tumor/genética
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, N.I.H., EXTRAMURAL; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (BCOR protein, human); 0 (CIC protein, human); 0 (FOXR2 protein, human); 0 (Forkhead Transcription Factors); 0 (MN1 protein, human); 0 (Proto-Oncogene Proteins); 0 (Repressor Proteins); 0 (Tumor Suppressor Proteins)
[Em] Mês de entrada:1607
[Cu] Atualização por classe:170810
[Lr] Data última revisão:
170810
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160227
[St] Status:MEDLINE
[do] DOI:10.1016/j.cell.2016.01.015


  7 / 393 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:26919424
[Au] Autor:Zaky W
[Ad] Endereço:Department of Pediatrics, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA. Electronic address: wzaky@mdanderson.org.
[Ti] Título:Revisiting Management of Pediatric Brain Tumors with New Molecular Insights.
[So] Source:Cell;164(5):844-6, 2016 Feb 25.
[Is] ISSN:1097-4172
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Pediatric central nervous system primitive neuro-ectodermal brain tumors (CNS-PNETs) are rare tumors with ill-defined biological features. In this issue of Cell, Sturm et al. used state-of-the-art methods to interrogate these tumors' biology. Their integrated molecular analyses led them to propose a new molecular classification, with four new entities identified, that should get oncologists' attention.
[Mh] Termos MeSH primário: Neoplasias do Sistema Nervoso Central/genética
Neoplasias do Sistema Nervoso Central/patologia
Metilação de DNA
Tumores Neuroectodérmicos/genética
Tumores Neuroectodérmicos/patologia
[Mh] Termos MeSH secundário: Seres Humanos
[Pt] Tipo de publicação:COMMENT; JOURNAL ARTICLE
[Em] Mês de entrada:1607
[Cu] Atualização por classe:160227
[Lr] Data última revisão:
160227
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160227
[St] Status:MEDLINE


  8 / 393 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
PubMed Central Texto completo
Texto completo
[PMID]:26732900
[Au] Autor:Yu J; Yang H; Cui D; Li Y
[Ad] Endereço:Department of Neurosurgery, The First Hospital of Jilin University, 71 Xinmin Avenue, Changchun, 130021, People's Republic of China. jinluyu@hotmail.com.
[Ti] Título:Retrospective analysis of 14 cases of remote epidural hematoma as a postoperative complication after intracranial tumor resection.
[So] Source:World J Surg Oncol;14(1):1, 2016 Jan 06.
[Is] ISSN:1477-7819
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: The occurrence of remote epidural hematoma as a postoperative complication after intracranial tumor resection is rare. This study reviewed experiences treating these hematomas and speculated on the causes of this disease. This study reviewed the treatment experience of 14 such cases. METHODS: The 14 patients included 10 males and 4 females, with an age range of 19 to 65 years old. Six cases of tumors occurred in the sellar region, two cases in the lateral ventricle, one case in the fourth ventricle, one case in a cerebellar hemisphere, and four cases in other sites. Among them, five cases were complicated with supratentorial hydrocephalus. The tumors included five cases of meningioma tumors, two cases of pituitary adenomas, three cases of ependymomas, two cases of craniopharyngiomas, one case of astrocytoma, and one case of tuberculosis tumor. For the cases complicated with hydrocephalus, ventricular drainage was provided if needed, and the tumor resection was then performed, with close observation for postoperative changes. If neurological symptoms and disturbance of consciousness occurred, computed tomography (CT) examination was immediately performed. If a remote epidural hematoma was found, the hematoma was evacuated by craniotomy. The patients were followed up after surgery. In the five cases complicated with hydrocephalus, ventricular drainage was first provided for three cases. RESULTS: All of the 14 cases underwent total tumor resection, and postoperative remote epidural hematoma occurred in all cases, including eight cases on the ipsilateral side and adjacent to the supratentorial operative field; two cases occurred on the contralateral side; two cases occurred on bilateral sides; and two cases occurred in distant areas (with infratentorial surgery, the hematoma occurred on the supratentorial area). Postoperative remote epidural hematoma usually occurred 0.5-5 h after the tumor resection, when the tentorial hernia had already occurred. Following tumor resection and epidural hematoma evacuation, 13 patients were discharged with good recovery, and one patient died. CONCLUSIONS: The reduced intracranial pressure due to the intracranial tumor resection may be the cause of this hematoma. This type of epidural hematoma is acute and often occurs before hernia. Thus, the risk of remote epidural hematoma after intracranial tumor resection needs to be made known. Aggressive hematoma evacuation can often result in satisfactory outcomes for patients.
[Mh] Termos MeSH primário: Adenoma/cirurgia
Neoplasias Encefálicas/cirurgia
Hematoma Epidural Craniano/etiologia
Tumores Neuroectodérmicos/cirurgia
Complicações Pós-Operatórias
[Mh] Termos MeSH secundário: Adulto
Idoso
Craniotomia
Feminino
Seguimentos
Hematoma Epidural Craniano/diagnóstico
Hematoma Epidural Craniano/cirurgia
Seres Humanos
Imagem por Ressonância Magnética
Masculino
Meia-Idade
Complicações Pós-Operatórias/diagnóstico
Complicações Pós-Operatórias/cirurgia
Estudos Retrospectivos
Resultado do Tratamento
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1610
[Cu] Atualização por classe:170220
[Lr] Data última revisão:
170220
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160107
[St] Status:MEDLINE
[do] DOI:10.1186/s12957-015-0754-8


  9 / 393 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:26586017
[Au] Autor:Kervarrec T; Lecointre C; Kerdraon R; Bens G; Piquard A; Michenet P
[Ad] Endereço:Service d'anatomie pathologique, hôpital de la Source, 14, avenue de l'Hôpital, 45067 Orléans, France. Electronic address: thibault.kervarrec@etu.univ-tours.fr.
[Ti] Título:[Gastro-intestinal neuroectodermal tumor (GNET): A case report of a small intestine tumor with hepatic metastases].
[Ti] Título:Tumeur neuroectodermique gastro-intestinale (GNET) : à propos d'un cas de tumeur du grêle avec métastases hépatiques..
[So] Source:Ann Pathol;35(6):506-10, 2015 Dec.
[Is] ISSN:0242-6498
[Cp] País de publicação:France
[La] Idioma:fre
[Ab] Resumo:The gastro-intestinal neuroectodermal tumor (GNET) is a rare sarcoma of the digestive tract, which was recently recognised. The knowledge of the morphological, immunohistochemical and molecular diagnostic criteria is necessary to not mistake it for the metastasis of a melanoma or for another sarcoma of the digestive tract as the gastro-intestinal clear cells sarcoma or the malignant peripheral nervous system tumor (MPNST). We report the case of a 41-year-old patient with a GNET of the small intestine with hepatic metastasis. The histological examination showed a diffuse proliferation of epithelioid cells, which only express PS100. The presence EWSR1-ATF1 gene fusions with any melanocytic differentiation leads to the diagnosis of GNET.
[Mh] Termos MeSH primário: Neoplasias Intestinais/patologia
Neoplasias Hepáticas/secundário
Tumores Neuroectodérmicos/secundário
[Mh] Termos MeSH secundário: Adulto
Biomarcadores Tumorais/análise
Diagnóstico Diferencial
Febre/etiologia
Seres Humanos
Neoplasias Intestinais/genética
Neoplasias Hepáticas/diagnóstico
Masculino
Melanoma/diagnóstico
Tumores Neuroectodérmicos/diagnóstico
Tumores Neuroectodérmicos/genética
Proteínas de Fusão Oncogênicas/genética
Proteínas S100/análise
Sarcoma de Células Claras/diagnóstico
Perda de Peso
[Pt] Tipo de publicação:CASE REPORTS; ENGLISH ABSTRACT; JOURNAL ARTICLE; REVIEW
[Nm] Nome de substância:
0 (Biomarkers, Tumor); 0 (EWSR1-ATF1 fusion protein, human); 0 (Oncogene Proteins, Fusion); 0 (S100 Proteins)
[Em] Mês de entrada:1609
[Cu] Atualização por classe:151215
[Lr] Data última revisão:
151215
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:151121
[St] Status:MEDLINE


  10 / 393 MEDLINE  
              first record previous record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:26516248
[Au] Autor:Hinojosa CA; Torres-Machorro A; Lizola R; Anaya-Ayala JE
[Ad] Endereço:Department of Surgery, Section of Vascular Surgery and Endovascular Therapy, Instituto Nacional de Ciencias Medicas y Nutricion "Salvador Zubiran", Mexico, Mexico.
[Ti] Título:Open removal of a retained retrohepatic inferior vena cava filter with a residual primary neuroectodermal renal tumoral thrombus.
[So] Source:BMJ Case Rep;2015, 2015 Oct 29.
[Is] ISSN:1757-790X
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Primary neuroectodermal renal tumours (PNET) are rare and aggressive neoplasms; thrombosis of the inferior vena cava (IVC) is associated with this entity. We report here the case of a 19-year-old man who experienced a new onset of abdominal pain. A CT scan revealed a large left renal mass, perirenal haematoma and IVC thrombosis. Owing to an acute drop in haemoglobin and subsegmentary pulmonary embolism, he underwent emergency selective renal artery angiography and embolisation of bleeding vessels and IVC filter (IVCF) placement. Once stable, he underwent a left radical nephrectomy and IVC thrombectomy; the pathology report confirmed PNET. 6 months later, imaging revealed a residual tumoral thrombus in the IVCF located in the retrohepatic IVC. The patient underwent removal of this device and the thrombus via a right thoracoabdominal approach. He recovered well and at 4 months, he continues his chemotherapy cycles.
[Mh] Termos MeSH primário: Remoção de Dispositivo
Neoplasias Renais/cirurgia
Tumores Neuroectodérmicos/cirurgia
Trombose/cirurgia
Veia Cava Inferior/cirurgia
[Mh] Termos MeSH secundário: Seres Humanos
Neoplasias Renais/tratamento farmacológico
Masculino
Neoplasia Residual
Tumores Neuroectodérmicos/tratamento farmacológico
Radiografia
Reoperação
Trombectomia
Trombose/diagnóstico por imagem
Filtros de Veia Cava
Adulto Jovem
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Em] Mês de entrada:1608
[Cu] Atualização por classe:171029
[Lr] Data última revisão:
171029
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:151031
[St] Status:MEDLINE



página 1 de 40 ir para página                         
   


Refinar a pesquisa
  Base de dados : MEDLINE Formulário avançado   

    Pesquisar no campo  
1  
2
3
 
           



Search engine: iAH v2.6 powered by WWWISIS

BIREME/OPAS/OMS - Centro Latino-Americano e do Caribe de Informação em Ciências da Saúde