Base de dados : MEDLINE
Pesquisa : C04.557.465.625.630 [Categoria DeCS]
Referências encontradas : 195 [refinar]
Mostrando: 1 .. 10   no formato [Detalhado]

página 1 de 20 ir para página                         

  1 / 195 MEDLINE  
              next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:28291424
[Au] Autor:Nicosia G; Spennato P; Aliberti F; Cascone D; Quaglietta L; Errico ME; Muto M; Ionna F; Cinalli G
[Ad] Endereço:Departments of 1 Paediatric Neurosurgery.
[Ti] Título:Giant melanotic neuroectodermal tumor of infancy (melanotic progonoma) of the head and neck: report of a malignant case.
[So] Source:J Neurosurg Pediatr;19(5):538-545, 2017 May.
[Is] ISSN:1933-0715
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Melanotic neuroectodermal tumor of infancy is a rare congenital pigmented neoplasm of neural crest origin, locally aggressive, growing rapidly and developing during the 1st year of life. It most commonly arises from the maxilla, cranial vault, and mandible. Occasionally, it exhibits malignant behavior with local lymph nodes involvement. Cases misdiagnosed and left untreated for a long time can present challenges due to the tumor mass and infiltration. In these cases, adjuvant chemotherapy can be extremely helpful before radical excision. Authors of this report describe a 4-year-old boy from a developing country who was referred to their hospital with an ulcerated bulging lesion in the midline/right parietooccipital region, extending to the right laterocervical and parotid regions, resulting in significant craniofacial deformation. Magnetic resonance imaging of the brain revealed a highly enhancing tumor with intracranial and extracranial development extending mainly at the level of the right parietooccipital region, with lytic and hypertrophic alterations of the skull. The patient was managed with neoadjuvant and adjuvant chemotherapy and radically resective surgery on metastatic lymph nodes and the primary tumor of the skull. Scheduled radiotherapy was not performed, according to the parents' wishes. The patient returned to his native country where the lesion recurred, and he ultimately died approximately 10 months after the end of the treatment. The literature indicates that tumor removal alone has been the treatment of choice in most isolated cases, but in cases of highly advanced tumor with involvement of the skull and cervical lymph nodes, it is preferable to proceed with preoperative chemotherapy with the aim of reducing the tumor volume, allowing better technical conditions for complete surgical removal, and decreasing the risk of local recurrence or metastasis.
[Mh] Termos MeSH primário: Tumor Neuroectodérmico Melanótico/diagnóstico
Tumor Neuroectodérmico Melanótico/patologia
Neoplasias Cranianas/diagnóstico
Neoplasias Cranianas/patologia
[Mh] Termos MeSH secundário: Encéfalo/diagnóstico por imagem
Encéfalo/cirurgia
Pré-Escolar
Terapia Combinada
Diagnóstico Diferencial
Evolução Fatal
Seres Humanos
Metástase Linfática
Masculino
Tumor Neuroectodérmico Melanótico/terapia
Neoplasias Cranianas/tratamento farmacológico
Neoplasias Cranianas/cirurgia
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Em] Mês de entrada:1705
[Cu] Atualização por classe:170526
[Lr] Data última revisão:
170526
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170315
[St] Status:MEDLINE
[do] DOI:10.3171/2016.11.PEDS16509


  2 / 195 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:27916316
[Au] Autor:Creytens D; Ferdinande L; Lecoutere E; Van Dorpe J
[Ad] Endereço:Department of Pathology, Ghent University and Ghent University Hospital, Ghent, Belgium. Electronic address: david.creytens@uzgent.be.
[Ti] Título:Melanotic neuroectodermal tumour of infancy presenting as an undifferentiated round cell tumour in the soft tissue of the forearm.
[So] Source:Pathology;49(1):87-90, 2017 Jan.
[Is] ISSN:1465-3931
[Cp] País de publicação:England
[La] Idioma:eng
[Mh] Termos MeSH primário: Diferenciação Celular/fisiologia
Antebraço/patologia
Tumor Neuroectodérmico Melanótico/patologia
Neoplasias de Tecidos Moles/patologia
[Mh] Termos MeSH secundário: Biópsia/métodos
Proteínas de Ligação a Calmodulina/genética
Diferenciação Celular/genética
Seres Humanos
Lactente
Masculino
Tumor Neuroectodérmico Melanótico/diagnóstico
Tumor Neuroectodérmico Melanótico/genética
Tumor Neuroectodérmico Melanótico/cirurgia
Proteína EWS de Ligação a RNA
Proteínas de Ligação a RNA/genética
Neoplasias de Tecidos Moles/diagnóstico
Neoplasias de Tecidos Moles/genética
Neoplasias de Tecidos Moles/cirurgia
[Pt] Tipo de publicação:CASE REPORTS; LETTER
[Nm] Nome de substância:
0 (Calmodulin-Binding Proteins); 0 (EWSR1 protein, human); 0 (RNA-Binding Protein EWS); 0 (RNA-Binding Proteins)
[Em] Mês de entrada:1704
[Cu] Atualização por classe:171116
[Lr] Data última revisão:
171116
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161206
[St] Status:MEDLINE


  3 / 195 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
[PMID]:27595482
[Au] Autor:Foster KA; Choudhri A; Lingo R; Boop F
[Ad] Endereço:Departments of Radiology and Neurosurgery, Le Bonheur Children's Hospital, Memphis, Tenn., USA.
[Ti] Título:Melanotic Neuroectodermal Tumor of Infancy with Involvement of the Superior Sagittal Sinus.
[So] Source:Pediatr Neurosurg;52(1):36-40, 2017.
[Is] ISSN:1423-0305
[Cp] País de publicação:Switzerland
[La] Idioma:eng
[Ab] Resumo:Melanotic neuroectodermal tumor of infancy (MNTI) is a rare lesion that typically manifests in the first year of life, most commonly involving the facial bones. We present 2 infants with MNTI involving the posterior skull with associated compression of the superior sagittal sinus (SSS). A review of the anatomical locations of MNTI is offered, and the implications of SSS involvement are described. This represents the first known description of MNTI with involvement of the posterior SSS.
[Mh] Termos MeSH primário: Tumor Neuroectodérmico Melanótico/diagnóstico por imagem
Tumor Neuroectodérmico Melanótico/cirurgia
Seio Sagital Superior/diagnóstico por imagem
Seio Sagital Superior/cirurgia
[Mh] Termos MeSH secundário: Feminino
Seres Humanos
Lactente
Masculino
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Em] Mês de entrada:1703
[Cu] Atualização por classe:170314
[Lr] Data última revisão:
170314
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160906
[St] Status:MEDLINE


  4 / 195 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:27539769
[Au] Autor:Mahmood UB; Khan FW; Fatima B; Tariq MU; Fatimi SH
[Ad] Endereço:Medical Student, The Aga Khan University, Karachi.
[Ti] Título:Primary Melanotic Schwannoma with Typical Histology.
[So] Source:J Coll Physicians Surg Pak;26(8):707-9, 2016 Aug.
[Is] ISSN:1681-7168
[Cp] País de publicação:Pakistan
[La] Idioma:eng
[Ab] Resumo:We present a case of a 17-year male with a soft tissue density spreading from the neural foramina (T3) of the spinal cord and involving the right upper thoracic cavity. We managed the patient through surgical intervention and resected the complete tumor. Gross definition and microscopic findings of the resected tissue revealed the definitive diagnosis of melanotic schwannoma. The histological characteristics in this case were very specific and harbour an important diagnostic clue for this rare disease. Malignant melanoma was ruled out on the basis of histological findings. The patient recovered completely and was healthy on one-year follow-up.
[Mh] Termos MeSH primário: Neurilemoma/cirurgia
Tumor Neuroectodérmico Melanótico/cirurgia
Neoplasias da Medula Espinal/cirurgia
Raízes Nervosas Espinhais/cirurgia
[Mh] Termos MeSH secundário: Adolescente
Seres Humanos
Masculino
Neurilemoma/diagnóstico
Tumor Neuroectodérmico Melanótico/diagnóstico
Neoplasias da Medula Espinal/diagnóstico
Espaço Subdural/patologia
Espaço Subdural/cirurgia
Vértebras Torácicas
Toracotomia
Resultado do Tratamento
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Em] Mês de entrada:1706
[Cu] Atualização por classe:170630
[Lr] Data última revisão:
170630
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160820
[St] Status:MEDLINE
[do] DOI:2411


  5 / 195 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
PubMed Central Texto completo
Texto completo
[PMID]:27519597
[Au] Autor:Barnes DJ; Hookway E; Athanasou N; Kashima T; Oppermann U; Hughes S; Swan D; Lueerssen D; Anson J; Hassan AB
[Ad] Endereço:Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Nuffield Orthopaedic Centre, Windmill Road, Headington, Oxford, OX3 7HE, UK.
[Ti] Título:A germline mutation of CDKN2A and a novel RPLP1-C19MC fusion detected in a rare melanotic neuroectodermal tumor of infancy: a case report.
[So] Source:BMC Cancer;16:629, 2016 08 12.
[Is] ISSN:1471-2407
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Melanotic neuroectodermal tumor of infancy (MNTI) is exceptionally rare and occurs predominantly in the head and neck (92.8 % cases). The patient reported here is only the eighth case of MNTI presenting in an extremity, and the first reported in the fibula. CASE PRESENTATION: A 2-month-old female presented with a mass arising in the fibula. Exhaustive genomic, transcriptomic, epigenetic and pathological characterization was performed on the excised primary tumor and a derived cell line. Whole-exome analysis of genomic DNA from both the tumor and blood indicated no somatic, non-synonymous coding mutations within the tumor, but a heterozygous, unique germline, loss of function mutation in CDKN2A (p16(INK4A), D74A). SNP-array CGH on DNA samples revealed the tumor to be euploid, with no detectable gene copy number variants. Multiple chromosomal translocations were identified by RNA-Seq, and fusion genes included RPLP1-C19MC, potentially deregulating the C19MC cluster, an imprinted locus containing microRNA genes reactivated by gene fusion in embryonal tumors with multilayered rosettes. Since the presumed cell of origin of MNTI is from the neural crest, we also compared gene expression with a dataset from human neural crest cells and identified 185 genes with significantly different expression. Consistent with the melanotic phenotype of the tumor, elevated expression of tyrosinase was observed. Other highly expressed genes encoded muscle proteins and modulators of the extracellular matrix. A derived MNTI cell line was sensitive to inhibitors of lysine demethylase, but not to compounds targeting other epigenetic regulators. CONCLUSIONS: In the absence of somatic copy number variations or mutations, the fully transformed phenotype of the MNTI may have arisen in infancy because of the combined effects of a germline CDKN2A mutation, tumor promoting somatic fusion genes and epigenetic deregulation. Very little is known about the etiology of MNTI and this report advances knowledge of these rare tumors by providing the first comprehensive genomic, transcriptomic and epigenetic characterization of a case.
[Mh] Termos MeSH primário: Neoplasias Ósseas/genética
Inibidor de Quinase Dependente de Ciclina p18/genética
Fíbula/patologia
Mutação em Linhagem Germinativa
Tumor Neuroectodérmico Melanótico/genética
Proteínas de Fusão Oncogênicas/genética
[Mh] Termos MeSH secundário: Feminino
Regulação Neoplásica da Expressão Gênica
Seres Humanos
Lactente
Fosfoproteínas/genética
Proteínas Ribossômicas/genética
Análise de Sequência de DNA
Análise de Sequência de RNA
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (CDKN2A protein, human); 0 (Cyclin-Dependent Kinase Inhibitor p18); 0 (Oncogene Proteins, Fusion); 0 (Phosphoproteins); 0 (Ribosomal Proteins); 0 (ribosomal phosphoprotein P1)
[Em] Mês de entrada:1709
[Cu] Atualização por classe:171121
[Lr] Data última revisão:
171121
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160814
[St] Status:MEDLINE
[do] DOI:10.1186/s12885-016-2669-3


  6 / 195 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:27510702
[Au] Autor:Khurana A; Singaravel S; Mukherjee U
[Ad] Endereço:Department of Pathology, Max Super Speciality Hospital, New Delhi, India.
[Ti] Título:Salivary gland anlage tumor.
[So] Source:Indian J Pathol Microbiol;59(3):431-3, 2016 Jul-Sep.
[Is] ISSN:0974-5130
[Cp] País de publicação:India
[La] Idioma:eng
[Mh] Termos MeSH primário: Nasofaringe/patologia
Tumor Neuroectodérmico Melanótico/diagnóstico
Tumor Neuroectodérmico Melanótico/patologia
Neoplasias Faríngeas/diagnóstico
Neoplasias Faríngeas/patologia
[Mh] Termos MeSH secundário: Biomarcadores Tumorais/análise
Cabeça/diagnóstico por imagem
Histocitoquímica
Seres Humanos
Imuno-Histoquímica
Lactente
Queratinas/análise
Masculino
Microscopia
Nasofaringe/diagnóstico por imagem
Pescoço/diagnóstico por imagem
Tumor Neuroectodérmico Melanótico/diagnóstico por imagem
Neoplasias Faríngeas/diagnóstico por imagem
Tomografia Computadorizada por Raios X
Vimentina/análise
[Pt] Tipo de publicação:CASE REPORTS; LETTER
[Nm] Nome de substância:
0 (Biomarkers, Tumor); 0 (Vimentin); 68238-35-7 (Keratins)
[Em] Mês de entrada:1703
[Cu] Atualização por classe:170313
[Lr] Data última revisão:
170313
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160812
[St] Status:MEDLINE
[do] DOI:10.4103/0377-4929.188147


  7 / 195 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:27510658
[Au] Autor:Jagtap SV
[Ad] Endereço:Department of Pathology, Krishna Institute of Medical Sciences University, Karad, Maharashtra, India.
[Ti] Título:Salivary gland anlage tumor in a neonate.
[So] Source:Indian J Pathol Microbiol;59(3):273, 2016 Jul-Sep.
[Is] ISSN:0974-5130
[Cp] País de publicação:India
[La] Idioma:eng
[Mh] Termos MeSH primário: Obstrução das Vias Respiratórias/etiologia
Obstrução das Vias Respiratórias/patologia
Tumor Neuroectodérmico Melanótico/complicações
Tumor Neuroectodérmico Melanótico/patologia
Neoplasias das Glândulas Salivares/complicações
Neoplasias das Glândulas Salivares/patologia
[Mh] Termos MeSH secundário: Obstrução das Vias Respiratórias/diagnóstico
Amilases/análise
Biomarcadores Tumorais/análise
Seres Humanos
Recém-Nascido
Tumor Neuroectodérmico Melanótico/diagnóstico
Neoplasias das Glândulas Salivares/diagnóstico
[Pt] Tipo de publicação:EDITORIAL
[Nm] Nome de substância:
0 (Biomarkers, Tumor); EC 3.2.1.- (Amylases)
[Em] Mês de entrada:1703
[Cu] Atualização por classe:170313
[Lr] Data última revisão:
170313
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160812
[St] Status:MEDLINE
[do] DOI:10.4103/0377-4929.188116


  8 / 195 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:27460453
[Au] Autor:Ng J; Munoz DG
[Ad] Endereço:Department of Pathology and Laboratory Medicine, University of Toronto, 27 King's College Cir, Toronto, ON M5S 1A1, Canada.
[Ti] Título:Pitfalls and uncertain prognosis in pathological diagnosis of psammomatous melanotic schwannoma.
[So] Source:J Clin Neurosci;33:236-239, 2016 Nov.
[Is] ISSN:1532-2653
[Cp] País de publicação:Scotland
[La] Idioma:eng
[Ab] Resumo:A 20-year-old woman presenting with a pelvic mass identified as a psammomatous melanotic schwannoma (PMS) with atypical histological features was later found to have family history of cardiac myxomas consistent with Carney's complex. The BRAF V600E mutation was absent in the tumor.
[Mh] Termos MeSH primário: Neurilemoma/diagnóstico
Neurilemoma/patologia
Tumor Neuroectodérmico Melanótico/diagnóstico
Tumor Neuroectodérmico Melanótico/patologia
[Mh] Termos MeSH secundário: Saúde da Família
Feminino
Seres Humanos
Mutação
Mixoma/diagnóstico
Neurilemoma/genética
Tumor Neuroectodérmico Melanótico/genética
Prognóstico
Proteínas Proto-Oncogênicas B-raf/genética
Adulto Jovem
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Nm] Nome de substância:
EC 2.7.11.1 (BRAF protein, human); EC 2.7.11.1 (Proto-Oncogene Proteins B-raf)
[Em] Mês de entrada:1702
[Cu] Atualização por classe:170210
[Lr] Data última revisão:
170210
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160728
[St] Status:MEDLINE


  9 / 195 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:27393580
[Au] Autor:Azarisamani A; Petrisor D; Wright J; Ghali GE
[Ad] Endereço:Resident, Department of Oral and Maxillofacial Surgery, Oregon Health & Science University, Portland, OR.
[Ti] Título:Metastatic Melanotic Neuroectodermal Tumor of Infancy: Report of a Case and Review of the Literature.
[So] Source:J Oral Maxillofac Surg;74(12):2431-2440, 2016 Dec.
[Is] ISSN:1531-5053
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Melanotic neuroectodermal tumors of infancy (MNTI) are rapidly growing pigmented tumors that occur predominantly within bony head and neck structures. There are fewer than 400 cases reported in the literature with the majority affecting the maxilla. Locations in other intraosseous and extraosseous structures have been characterized, including the mandible (6% of MNTIs). Infants in the first year of life are primarily affected. Surgical resection is the primary treatment modality with and without adjuvant chemotherapy for malignant tumors, which comprise less than 25 cases in the literature, and of metatstatic mandibular tumors, which has only been documented in one other case. The purpose of this investigation is to review associated literature and present a case highlighting treatment considerations of a metastatic mandibular MNTI. We present the case of a six month old boy with a rapidly growing bluish mass of the right mandible. Preoperatively incisional biopsy led to a diagnosis of MNTI and subsequent surgical planning involved hemimandibulectomy from the right mandibular condyle to the left posterior body region with one centimeter margins. At the time of initial surgery, enlarged lymph nodes removed from the neck demonstrated abnormality consistent with metastatic spread of the tumor. Islands of tumor cells were noted: small, round, bluestaining cells resembling neuroblasts with mitotic activity as well as pigmented cells containing melanin. Because of regional node metastasis, chemotherapy was completed following surgery. The patient recovered and was followed without evidence of recurrence. At 3.5 years postresection, a secondary reconstruction was completed using a fibula osteocutaneous free flap combined with a costochondral rib graft. In reviewing similar cases of malignant MNTI reported in the literature, a search of the MEDLINE database until 2014 was performed. These were evaluated based on management type and outcome, including surgical and chemotherapeutic treatments and the incidence of recurrence or metastasis.
[Mh] Termos MeSH primário: Neoplasias Mandibulares/cirurgia
Osteotomia Mandibular
Reconstrução Mandibular
Tumor Neuroectodérmico Melanótico/cirurgia
[Mh] Termos MeSH secundário: Seres Humanos
Lactente
Metástase Linfática
Masculino
Neoplasias Mandibulares/diagnóstico
Neoplasias Mandibulares/patologia
Pescoço
Tumor Neuroectodérmico Melanótico/diagnóstico
Tumor Neuroectodérmico Melanótico/patologia
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE; REVIEW
[Em] Mês de entrada:1705
[Cu] Atualização por classe:170817
[Lr] Data última revisão:
170817
[Sb] Subgrupo de revista:AIM; D; IM
[Da] Data de entrada para processamento:160710
[St] Status:MEDLINE


  10 / 195 MEDLINE  
              first record previous record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:27107579
[Au] Autor:Maroun C; Khalifeh I; Alam E; Akl PA; Saab R; Moukarbel RV
[Ad] Endereço:Faculty of Medicine, American University of Beirut Medical Center, Beirut, Lebanon.
[Ti] Título:Mandibular melanotic neuroectodermal tumor of infancy: a role for neoadjuvant chemotherapy.
[So] Source:Eur Arch Otorhinolaryngol;273(12):4629-4635, 2016 Dec.
[Is] ISSN:1434-4726
[Cp] País de publicação:Germany
[La] Idioma:eng
[Ab] Resumo:Melanotic Neuroectodermal Tumor of Infancy (MNTI) is a rare, locally aggressive neoplasm with a predilection for the head and neck area, most commonly occurring in the maxilla. The vast majority of treatment modalities for all cases of MNTI to date have involved surgical intervention only, with just 9.6 % involving some sort of chemotherapy, radiotherapy, or a combination of the prior mentioned modalities. There is very limited information available regarding the use of neoadjuvant chemotherapy, due to its rare nature. In this report, a 4 month old girl presented to our clinic with a chief complaint of a large oral mass of about 2.5 months in duration. Intraoral examination showed an oral mass arising from the lingual aspect of inferior alveolar ridge with extensive mandibular invasion. The patient received three cycles of vincristine, Adriamycin, and cyclophosphamide as neodajuvant therapy. Upon completion, the tumor had decreased significantly in size. The patient was then scheduled for surgery and underwent surgical resection of the tumor. We were able to obtain adequate shrinkage of the tumor to allow better resectability, easier surgical access and a more minimally invasive approach with no lip split and a smaller neck incision. In conclusion, we have reported an extremely rare case of MNTI of the mandible that was successfully treated with neoadjuvant chemotherapy and surgical resection. This approach was advantageous to minimize the chance of recurrence and improve resectability in particularly large tumors, while maximizing functional outcomes and minimizing deformity.
[Mh] Termos MeSH primário: Protocolos de Quimioterapia Combinada Antineoplásica/uso terapêutico
Neoplasias Mandibulares/terapia
Tumor Neuroectodérmico Melanótico/terapia
[Mh] Termos MeSH secundário: Ciclofosfamida/administração & dosagem
Doxorrubicina/administração & dosagem
Feminino
Seres Humanos
Lactente
Neoplasias Mandibulares/patologia
Terapia Neoadjuvante
Tumor Neuroectodérmico Melanótico/patologia
Doenças Raras
Vincristina/administração & dosagem
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Nm] Nome de substância:
5J49Q6B70F (Vincristine); 80168379AG (Doxorubicin); 8N3DW7272P (Cyclophosphamide)
[Em] Mês de entrada:1703
[Cu] Atualização por classe:170928
[Lr] Data última revisão:
170928
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160425
[St] Status:MEDLINE
[do] DOI:10.1007/s00405-016-4066-6



página 1 de 20 ir para página                         
   


Refinar a pesquisa
  Base de dados : MEDLINE Formulário avançado   

    Pesquisar no campo  
1  
2
3
 
           



Search engine: iAH v2.6 powered by WWWISIS

BIREME/OPAS/OMS - Centro Latino-Americano e do Caribe de Informação em Ciências da Saúde