Base de dados : MEDLINE
Pesquisa : C04.557.665.560.615.550 [Categoria DeCS]
Referências encontradas : 673 [refinar]
Mostrando: 1 .. 10   no formato [Detalhado]

página 1 de 68 ir para página                         

  1 / 673 MEDLINE  
              next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:29465551
[Au] Autor:Wang KL; Ma SF; Pang LY; Zhang MN; Hu LY; Liu MJ; Zou LP
[Ad] Endereço:Department of Pediatrics, Chinese PLA General Hospital, Beijing, China.
[Ti] Título:Sirolimus alternative to blood transfusion as a life saver in blue rubber bleb nevus syndrome: A case report.
[So] Source:Medicine (Baltimore);97(8):e9453, 2018 Feb.
[Is] ISSN:1536-5964
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:RATIONALE: Blue rubber bleb nevus syndrome (BRBNS) is a rare disease characterized by multiple venous malformations. The gastrointestinal bleeding and secondary iron deficiency anemia are the most common complications. There are currently no effective treatments for BRBNS. Here, we report a case of successful treatment with a small dose of sirolimus of a BRBN patient with a de novo gene mutation. PATIENT CONCERNS: A 12-year-old female was admitted to our hospital with multiple hemangiomas for 12 years. The patient often displayed melena; she recently received transfusion of 2 units of red blood cells once every 2 weeks. Multiple fist-sized hemangiomas were piled up on both sides and back of the neck, and were also noted on the arms, legs, chest, back, and on the tip of the tongue. The laboratory findings demonstrated severe anemia. Blood sample sequencing detected a heterozygous de novo mutation c.2545C > Tin the TEK gene. DIAGNOSES: Based on these findings, final diagnosis of Blue rubber bleb nevus syndrome (BRBNS) was made. INTERVENTIONS: After the diagnosis, low-dose sirolimus was orally administered. OUTCOMES: The patient's hemoglobin was increased after treatment with sirolimus for 1 month. Since the initial treatment with sirolimus, she had not received any blood transfusions. The skin and mucosal hemangioma decreased significantly, and new digestive tract hemorrhage, muscle hematoma, or adverse drug reactions were not observed. LESSONS: we report a case of a mutation in exon 15 of the TEK gene leading to BRBN. It was successfully treated with a small dose of sirolimus as an alternative to blood transfusion in order to save the of BRBN patient's life.
[Mh] Termos MeSH primário: Neoplasias Gastrointestinais/tratamento farmacológico
Imunossupressores/administração & dosagem
Nevo Azul/tratamento farmacológico
Sirolimo/administração & dosagem
Neoplasias Cutâneas/tratamento farmacológico
[Mh] Termos MeSH secundário: Transfusão de Sangue
Criança
Feminino
Neoplasias Gastrointestinais/diagnóstico
Neoplasias Gastrointestinais/genética
Seres Humanos
Mutação
Nevo Azul/diagnóstico
Nevo Azul/genética
Neoplasias Cutâneas/diagnóstico
Neoplasias Cutâneas/genética
Resultado do Tratamento
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Immunosuppressive Agents); W36ZG6FT64 (Sirolimus)
[Em] Mês de entrada:1803
[Cu] Atualização por classe:180302
[Lr] Data última revisão:
180302
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:180222
[St] Status:MEDLINE
[do] DOI:10.1097/MD.0000000000009453


  2 / 673 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:28816965
[Au] Autor:Chen W; Chen H; Shan G; Yang M; Hu F; Li Q; Chen L; Xu G
[Ad] Endereço:aDepartment of Gastroenterology, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, Zhejiang Province bDepartment of Nephrology, Jilin City Central Hospital, Jilin, Jilin Province, China.
[Ti] Título:Blue rubber bleb nevus syndrome: our experience and new endoscopic management.
[So] Source:Medicine (Baltimore);96(33):e7792, 2017 Aug.
[Is] ISSN:1536-5964
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:The aim of our study is to enhance the awareness of blue rubber bleb nevus syndrome (BRBNS) through the patients in our hospital and introduced a new measure of endoscopic intervention.A retrospective review of 5 patients, who were diagnosed as BRBNS in our hospital from January 2013 to January 2017, was conducted. Data were collected with regard to demographics, clinical presentation, endoscopic and imaging findings, management, and follow-up data.In total of 5 patients, the mean age was 28.8 years, range 16 to 44 years (male/female, 1/4) with the average initial age of onset 15.4 years. No family history was identified in our group. Physical examination showed multiple cutaneous lesions in 2 patients (40%, 2/5). All the 5 patients had gastrointestinal tract vascular malformations; stomach involved in 2 cases, large intestine in 2 cases, and small intestine involved in 3 cases. Lesions in the visceral organs and tissue were found in 1 patient. Gastrointestinal bleeding was its main symptom (3/5, 60%). Laboratory investigations revealed anemia in 4 patients and abnormality of coagulopathy in 2 patients with severe anemia. Conservative approach was recommended in 3 cases that included iron supplementation, drug hemostasis, and/or blood transfusion. An innovatively therapeutic approach with endoscopic submucosal dissection (ESD) procedure was used successfully in 1 patient with 2 polypoid BRBNS lesions in rectum.BRBNS is a very rare vascular malformation syndrome with unclear etiopathogenesis and noncurative treatments. ESD procedure was a feasible approach to remove the partial gastrointestinal lesions.
[Mh] Termos MeSH primário: Ressecção Endoscópica de Mucosa/métodos
Neoplasias Gastrointestinais/patologia
Neoplasias Gastrointestinais/cirurgia
Nevo Azul/patologia
Nevo Azul/cirurgia
Neoplasias Cutâneas/patologia
Neoplasias Cutâneas/cirurgia
[Mh] Termos MeSH secundário: Adolescente
Adulto
Feminino
Seres Humanos
Masculino
Estudos Retrospectivos
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE; OBSERVATIONAL STUDY
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170911
[Lr] Data última revisão:
170911
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:170818
[St] Status:MEDLINE
[do] DOI:10.1097/MD.0000000000007792


  3 / 673 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:28796000
[Au] Autor:Cohen JN; Joseph NM; North JP; Onodera C; Zembowicz A; LeBoit PE
[Ad] Endereço:Departments of *Pathology §Dermatopathology ∥Dermatology †Clinical Cancer Genomics Laboratory ‡Helen Diller Cancer Center, University of California, San Francisco, CA ¶Department of Pathology, Lahey Clinic, Burlington, MA.
[Ti] Título:Genomic Analysis of Pigmented Epithelioid Melanocytomas Reveals Recurrent Alterations in PRKAR1A, and PRKCA Genes.
[So] Source:Am J Surg Pathol;41(10):1333-1346, 2017 Oct.
[Is] ISSN:1532-0979
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Pigmented epithelioid melanocytoma (PEM) is a rare cutaneous melanocytic tumor first described as epithelioid blue nevus in patients with the Carney Complex (CC). PEM was among the first established examples of an intermediate class of melanocytic tumors, including atypical Spitz tumors, with frequent metastasis to lymph nodes but only rare extranodal spread. Sporadic and CC-associated PEM are essentially histologically indistinguishable. A subset of PEM shows loss of cytoplasmic expression of the protein kinase A regulatory subunit alpha (PRKAR1A), a tumor suppressor gene mutated in 70% of families with CC. However, molecular studies of such tumors have been limited. Therefore, we used next-generation sequencing to assess 480 cancer-related genes and performed PrkaR1α immunohistochemistry on 13 cases morphologically consistent with PEM. Six cases demonstrated loss of PrkaR1α expression by immunohistochemistry. Three cases were "combined" PEM arising in association with a common nevus. These lesions harbored PRKAR1A genetic alterations in addition to BRAF mutations. Three "pure" PEM, not associated with a common nevus, showed no evidence of PRKAR1A genetic alterations despite loss of PrkaR1α expression. Two of these PEM demonstrated MAP2K1 in frame deletions. PrkaR1α protein expression was preserved in 7 cases. Two of these lesions revealed fusions of the gene encoding the protein kinase C alpha isoform (PRKCA) to 2 distinct partners (ATP2B4-PRKCA and RNF13-PRKCA). Two lesions may represent misdiagnosed "blue nevus with epithelioid features" as they demonstrated GNAQ hotspot mutations. A conceivable explanation, but one we do not favor is that rare PEM are caused by GNAQ mutations. No genetic aberrations were detected in 3 lesions. None of our 13 cases demonstrated TERT alterations or significant chromosomal copy number changes. These results further validate the concept of PEM as a distinctive intermediate/borderline melanocytic tumor, and also illustrate its molecular heterogeneity.
[Mh] Termos MeSH primário: Subunidade RIalfa da Proteína Quinase Dependente de AMP Cíclico/genética
Genômica
Nevo Azul/genética
Nevo Azul/patologia
Proteína Quinase C-alfa/genética
Neoplasias Cutâneas/genética
Neoplasias Cutâneas/patologia
[Mh] Termos MeSH secundário: Adulto
Criança
Pré-Escolar
Feminino
Seres Humanos
Masculino
Meia-Idade
Mutação
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Cyclic AMP-Dependent Protein Kinase RIalpha Subunit); 0 (PRKAR1A protein, human); EC 2.7.11.13 (PRKCA protein, human); EC 2.7.11.13 (Protein Kinase C-alpha)
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171002
[Lr] Data última revisão:
171002
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170811
[St] Status:MEDLINE
[do] DOI:10.1097/PAS.0000000000000902


  4 / 673 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:28416343
[Au] Autor:Bax MJ; Brown MD; Rothberg PG; Laughlin TS; Scott GA
[Ad] Endereço:Department of Dermatology, University of Rochester School of Medicine, Rochester, New York. Electronic address: Michael.Bax@RoswellPark.org.
[Ti] Título:Pigmented epithelioid melanocytoma (animal-type melanoma): An institutional experience.
[So] Source:J Am Acad Dermatol;77(2):328-332, 2017 Aug.
[Is] ISSN:1097-6787
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Pigmented epithelioid melanocytoma (PEM) is an uncommon, recently described entity with unknown biologic behavior. There is a high rate of regional metastases, but limited evidence of distant metastases or disease-related death. OBJECTIVE: We sought to report our series of patients given a diagnosis of PEM at our institution and provide mutational analysis of genes commonly implicated in melanoma in 2 cases. METHODS: The pathology database was queried for cases of PEM diagnosed at the University of Rochester. Charts were reviewed for follow-up information. Mutational analysis of melanoma-associated genes was performed on 2 cases. RESULTS: Nine cases of PEM were retrieved in a 10-year retrospective review. Five patients underwent sentinel lymph node biopsy with 3 of 5 having a positive sentinel lymph node. All 9 patients are alive and disease-free with average follow-up of 38.75 months. Two tumors were tested for common melanoma-associated mutations, and were negative, except for a telomerase reverse transcriptase promoter deletion detected in 1 sample. The deletion has not been associated with melanoma, and therefore its biologic significance is unclear. LIMITATIONS: Small sample size, retrospective nature, and single institution experience are limitations. CONCLUSIONS: PEM appears to have an indolent behavior. However, currently the evidence is too limited to provide insight into its true biologic potential.
[Mh] Termos MeSH primário: Melanoma/secundário
Nevo Azul/patologia
Neoplasias Cutâneas/patologia
[Mh] Termos MeSH secundário: Adolescente
Adulto
Criança
Pré-Escolar
Análise Mutacional de DNA
Feminino
Seres Humanos
Metástase Linfática
Masculino
Melanoma/genética
Melanoma/cirurgia
Meia-Idade
Estadiamento de Neoplasias
Regiões Promotoras Genéticas
Estudos Retrospectivos
Biópsia de Linfonodo Sentinela
Neoplasias Cutâneas/genética
Neoplasias Cutâneas/cirurgia
Taxa de Sobrevida
Telomerase/genética
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
EC 2.7.7.49 (Telomerase)
[Em] Mês de entrada:1708
[Cu] Atualização por classe:170825
[Lr] Data última revisão:
170825
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170419
[St] Status:MEDLINE


  5 / 673 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
[PMID]:28329489
[Au] Autor:Klufas DM; Que SK; Berke A; Maryland BS
[Ti] Título:Acquired blue nevus of the nail bed.
[So] Source:Dermatol Online J;23(2), 2017 Feb 15.
[Is] ISSN:1087-2108
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Blue nevi are benign proliferations of melaninproducingdendritic melanocytes located in thedermis. These nevi tend to occur mostly on the skin,predominantly on the head and neck, dorsal aspectsof the distal extremities, and the sacral area, butcan also occasionally appear on mucosal surfaces.Blue nevi of the nail apparatus are uncommon. Themajority originate in the nail matrix where there is ahigher density of melanocytes. Herein we report ona 47-year-old man with a rare common blue nevus ofthe nail bed, an area with low melanocyte density. Athorough review of the English language literaturefound no documented cases of acquired blue nevioriginating in the nailbed of the toe.
[Mh] Termos MeSH primário: Doenças da Unha/diagnóstico
Nevo Azul/diagnóstico
Neoplasias Cutâneas/diagnóstico
[Mh] Termos MeSH secundário: Seres Humanos
Masculino
Meia-Idade
Doenças da Unha/patologia
Nevo Azul/patologia
Neoplasias Cutâneas/patologia
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171016
[Lr] Data última revisão:
171016
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170323
[St] Status:MEDLINE


  6 / 673 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:28240407
[Au] Autor:Popadic M; Sinz C; Kittler H
[Ad] Endereço:Department of Dermatovenereology, Medical University of Belgrade, Clinic of Dermatovenereology, Clinical Center of Serbia, Belgrade, Serbia.
[Ti] Título:The significance of blue color in dermatoscopy.
[So] Source:J Dtsch Dermatol Ges;15(3):302-307, 2017 Mar.
[Is] ISSN:1610-0387
[Cp] País de publicação:Germany
[La] Idioma:eng
[Ab] Resumo:BACKGROUND AND OBJECTIVES: Skin lesions with blue color are frequently excised to rule out malignancy. The objective of the present study was to investigate the significance of blue color. METHODS: We retrospectively scanned dermatoscopic images for blue color and classified them according to pattern analysis. RESULTS: Of 1,123 pigmented skin lesions, 144 (12.8 %) showed blue color, 92 of which (63.9 %) were malignant. Among lesions with blue color, the most common benign diagnoses were nevi (n = 35, 24.3 %) and seborrheic keratoses (n = 8, 5.6 %). Of 103 (71.5 %) lesions with a structureless blue pattern, eight (7.8 %) were entirely blue and 95 (92.2 %) were partly blue, of which 81 (78.6 %) showed peripheral or patchy and 14 (13.6 %) central blue color. Most lesions with peripheral or patchy blue color were melanomas (n = 47, 58 %), whereas most lesions with central blue color were nevi (n = 9, 64.3 %). Of 28 lesions with blue clods, 17 (60.7 %) were basal cell carcinomas. With respect to malignancy, the positive predictive value of blue color was 63.9 % (95 % CI: 56.0-71.8 %). CONCLUSIONS: Among malignant lesions with blue color, structureless peripheral or patchy blue color is a clue for melanoma, while blue clods point to basal cell carcinoma. Pitfalls include seborrheic keratoses, which may show blue color, as well as some nevi, especially combined nevi.
[Mh] Termos MeSH primário: Carcinoma Basocelular/patologia
Cor
Dermoscopia/métodos
Ceratose Seborreica/patologia
Melanoma/patologia
Nevo Azul/patologia
Neoplasias Cutâneas/patologia
[Mh] Termos MeSH secundário: Adolescente
Adulto
Idoso
Idoso de 80 Anos ou mais
Criança
Colorimetria/métodos
Diagnóstico Diferencial
Feminino
Seres Humanos
Masculino
Meia-Idade
Reprodutibilidade dos Testes
Sensibilidade e Especificidade
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171030
[Lr] Data última revisão:
171030
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170228
[St] Status:MEDLINE
[do] DOI:10.1111/ddg.13192


  7 / 673 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo SciELO Brasil
[PMID]:28225968
[Au] Autor:Daltro LR; Yaegashi LB; Freitas RA; Fantini BC; Souza CD
[Ad] Endereço:Division of Dermatology, Internal Medicine Department - Medical School of Ribeirão Preto - Universidade de São Paulo- Ribeirão Preto (SP) -Brazil.
[Ti] Título:Atypical cellular blue nevus or malignant blue nevus?
[So] Source:An Bras Dermatol;92(1):110-112, 2017 Jan-Feb.
[Is] ISSN:1806-4841
[Cp] País de publicação:Brazil
[La] Idioma:eng
[Ab] Resumo:Blue nevus is a benign melanocytic lesion whose most frequent variants are dendritic (common) blue nevus and cellular blue nevus. Atypical cellular blue nevus presents an intermediate histopathology between the typical and a rare variant of malignant blue nevus/melanoma arising in a cellular blue nevus. An 8-year-old child presented a pigmented lesion in the buttock since birth, but with progressive growth in the last two years. After surgical excision, histopathological examination revealed atypical cellular blue nevus. Presence of mitoses, ulceration, infiltration, cytological atypia or necrosis may occur in atypical cellular blue nevus, making it difficult to differentiate it from melanoma. The growth of blue nevus is unusual and considered of high-risk for malignancy, being an indicator for complete resection and periodic follow-up of these patients.
[Mh] Termos MeSH primário: Nevo Azul/patologia
[Mh] Termos MeSH secundário: Criança
Diagnóstico Diferencial
Seres Humanos
Masculino
Neoplasias Cutâneas/patologia
[Pt] Tipo de publicação:CASE REPORTS
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171004
[Lr] Data última revisão:
171004
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170223
[St] Status:MEDLINE


  8 / 673 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:28146305
[Au] Autor:Huang YY; Vandergriff T
[Ad] Endereço:Baylor College of Medicine, Houston, Texas.
[Ti] Título:Balloon cell change in common blue nevus.
[So] Source:J Cutan Pathol;44(4):407-409, 2017 04.
[Is] ISSN:1600-0560
[Cp] País de publicação:United States
[La] Idioma:eng
[Mh] Termos MeSH primário: Melanócitos
Nevo Azul
[Mh] Termos MeSH secundário: Seres Humanos
Melanoma
Nevo Pigmentado
Neoplasias Cutâneas
[Pt] Tipo de publicação:LETTER; COMMENT
[Em] Mês de entrada:1708
[Cu] Atualização por classe:170817
[Lr] Data última revisão:
170817
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170202
[St] Status:MEDLINE
[do] DOI:10.1111/cup.12895


  9 / 673 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
[PMID]:28141567
[Au] Autor:Akyuz C; Susam-Sen H; Aydin B
[Ad] Endereço:Department of Pediatric Oncology, Hacettepe University, Cancer Institute, 06100 Ankara-Turkey. Correspondence to: Dr Burca Aydin, Department of Pediatric Oncology, Hacettepe University, Cancer Institute, 06100 Ankara-Turkey. burcaaydin@yahoo.com.
[Ti] Título:Blue Rubber Bleb Nevus Syndrome: Promising Response To Sirolimus.
[So] Source:Indian Pediatr;54(1):53-54, 2017 Jan 15.
[Is] ISSN:0974-7559
[Cp] País de publicação:India
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Blue rubber bleb nevus syndrome is a rare disease involving venous malformations. CASE CHARACTERISTICS: We present a 6-year-old female with the syndrome, and consumptive coagulopathy. INTERVENTION/OUTCOME: After management with sirolimus, symptoms resolved. MESSAGE: Sirolimus may be a valuable option for reducing bleeding complications and cosmetic sequelae for the patients with this syndrome.
[Mh] Termos MeSH primário: Antibióticos Antineoplásicos/uso terapêutico
Neoplasias Gastrointestinais/tratamento farmacológico
Neoplasias Gastrointestinais/patologia
Nevo Azul/tratamento farmacológico
Nevo Azul/patologia
Sirolimo/uso terapêutico
Neoplasias Cutâneas/tratamento farmacológico
Neoplasias Cutâneas/patologia
[Mh] Termos MeSH secundário: Criança
Feminino
Hemangioma
Seres Humanos
Pele/patologia
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Antibiotics, Antineoplastic); W36ZG6FT64 (Sirolimus)
[Em] Mês de entrada:1705
[Cu] Atualização por classe:170817
[Lr] Data última revisão:
170817
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170201
[St] Status:MEDLINE


  10 / 673 MEDLINE  
              first record previous record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:28010758
[Au] Autor:Arbiser JL; Gilbert LC
[Ad] Endereço:Department of Dermatology, Emory University School of Medicine, Atlanta Veterans Administration Medical Center, Winship Cancer Institute, Atlanta, Georgia, USA. Electronic address: jarbise@emory.edu.
[Ti] Título:Double Jeopardy: The Rubber Ball Bounces Twice.
[So] Source:J Invest Dermatol;137(1):15-17, 2017 Jan.
[Is] ISSN:1523-1747
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Soblet et al. describe cis mutations in TEK/Tie-2 in blue rubber bleb nevus and sporadic vascular malformations. This suggests that the remaining normal allele is required for the phenotype. Second, it suggests therapeutic approaches to treatment signal transduction inhibition.
[Mh] Termos MeSH primário: Neoplasias Gastrointestinais/genética
Proteínas dos Microtúbulos/genética
Nevo Azul/genética
Neoplasias Cutâneas/genética
Proteínas Supressoras da Sinalização de Citocinas/genética
[Mh] Termos MeSH secundário: Adulto
Alelos
Neoplasias Gastrointestinais/patologia
Hemangioma Capilar/genética
Hemangioma Capilar/patologia
Seres Humanos
Lactente
Mutação
Nevo Azul/patologia
Fenótipo
Sensibilidade e Especificidade
Neoplasias Cutâneas/patologia
[Pt] Tipo de publicação:COMPARATIVE STUDY; JOURNAL ARTICLE; REVIEW
[Nm] Nome de substância:
0 (Microtubule Proteins); 0 (Suppressor of Cytokine Signaling Proteins); 0 (cytokine inducible SH2-containing protein); 0 (tektins)
[Em] Mês de entrada:1707
[Cu] Atualização por classe:170719
[Lr] Data última revisão:
170719
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161225
[St] Status:MEDLINE



página 1 de 68 ir para página                         
   


Refinar a pesquisa
  Base de dados : MEDLINE Formulário avançado   

    Pesquisar no campo  
1  
2
3
 
           



Search engine: iAH v2.6 powered by WWWISIS

BIREME/OPAS/OMS - Centro Latino-Americano e do Caribe de Informação em Ciências da Saúde