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Pesquisa : C04.557.665.560.615.585 [Categoria DeCS]
Referências encontradas : 278 [refinar]
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  1 / 278 MEDLINE  
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[PMID]:28398430
[Au] Autor:Jerdan K; Hsu JT; Schnurstein E
[Ad] Endereço:Department of Dermatology, University of Illinois at Chicago, USA.
[Ti] Título:Successful treatment of Ota nevus with the 532-nm solid-state picosecond laser.
[So] Source:Cutis;99(3):E29-E31, 2017 Mar.
[Is] ISSN:2326-6929
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Laser treatment of Ota nevi can be complicated, particularly in darker skin types, as there is a higher risk for adverse effects if the laser is not carefully employed. We report a case of successful treatment of an Ota nevus in a patient with Fitzpatrick skin type IV with the novel 532-nm solid-state picosecond laser after 2 treatments.
[Mh] Termos MeSH primário: Lasers de Estado Sólido/uso terapêutico
Nevo de Ota/cirurgia
Neoplasias Cutâneas/cirurgia
Pigmentação da Pele
[Mh] Termos MeSH secundário: Adolescente
Feminino
Seres Humanos
Lasers de Estado Sólido/efeitos adversos
Nevo de Ota/patologia
Neoplasias Cutâneas/patologia
Resultado do Tratamento
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Em] Mês de entrada:1707
[Cu] Atualização por classe:170707
[Lr] Data última revisão:
170707
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170412
[St] Status:MEDLINE


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[PMID]:28299489
[Au] Autor:Yongqian C; Li L; Jianhai B; Ran H; Li G; Hao W; Xining W; Shigang X; Yibing W
[Ad] Endereço:Department of Burns and Plastic Surgery, Provincial Hospital affiliated to Shandong University, Jinan, Shandong, China.
[Ti] Título:A split-face comparison of Q-switched Nd:YAG 1064-nm laser for facial rejuvenation in Nevus of Ota patients.
[So] Source:Lasers Med Sci;32(4):765-769, 2017 May.
[Is] ISSN:1435-604X
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:We aimed to investigate the efficacy and safety of using the 1064-nm Q-switched neodymium-doped yttrium aluminum garnet (Nd:YAG) laser (QSNYL) for skin rejuvenation in patients with Nevus of Ota. A retrospective, randomized, split-faced, clinical study was conducted. Twenty-nine patients with unilateral moderate to severe Nevus of Ota were enrolled. The participants completed 3-13 sessions of QSNYL treatments 3-6 months apart. Two independent physicians compared the treated and untreated sides of the face to evaluate the clearance of Nevus of Ota, the wrinkle severity rating scale (WSRS), the global aesthetic improvement scale (GAIS), and adverse event reporting. Patients' satisfaction levels were also considered. Of the 29 patients, 28 (96.6%) achieved nearly complete pigmentation clearance. After an average of 7.76 ± 2.99 sessions, statistically significant improvement in wrinkles and skin texture were observed, compared with the untreated side. The degree of skin rejuvenation was positively correlated with the number of treatment sessions. No clinically adverse effects were observed. Repeated QSNYL treatments not only remove the pigment in Nevus of Ota effectively and safely but also improve facial rejuvenation.
[Mh] Termos MeSH primário: Lasers de Estado Sólido/uso terapêutico
Nevo de Ota/radioterapia
Rejuvenescimento
Neoplasias Cutâneas/radioterapia
[Mh] Termos MeSH secundário: Adulto
Demografia
Feminino
Seres Humanos
Lasers de Estado Sólido/efeitos adversos
Masculino
Meia-Idade
Satisfação do Paciente
Pigmentação
Estudos Retrospectivos
[Pt] Tipo de publicação:COMPARATIVE STUDY; JOURNAL ARTICLE; RANDOMIZED CONTROLLED TRIAL
[Em] Mês de entrada:1708
[Cu] Atualização por classe:171013
[Lr] Data última revisão:
171013
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170317
[St] Status:MEDLINE
[do] DOI:10.1007/s10103-017-2161-6


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[PMID]:27058831
[Au] Autor:Jung S; Kwon T; Zhang CC; Chuck RS; Kwon JW
[Ad] Endereço:Department of Ophthalmology (S.J., J.W.K.), Myongji Hospital, Seonam University College of Medicine, Goyang, Korea; Department of Pathology (T.K.), Myongji Hospital, Seonam University College of Medicine, Goyang, Korea; and Department of Ophthalmology and Visual Sciences (C.C.Z., R.S.C., J.W.K.), Montefiore Medical Center, Albert Einstein College of Medicine, New York, NY.
[Ti] Título:A Novel Surgical Approach for Oculodermal Melanocytosis: Superficial Sclerectomy.
[So] Source:Eye Contact Lens;43(4):253-256, 2017 Jul.
[Is] ISSN:1542-233X
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:OBJECTIVE: To report the outcomes of a new surgical method for oculodermal melanocytosis (nevus of Ota)-superficial scleral separation. METHODS: Twenty-five eyes of 25 patients with scleral pigmentation arising from oculodermal melanocysis. These patients underwent superficial scleral separation between March 2012 and February 2013. Each patient was evaluated with the followings: ocular examinations, the preoperative extent of scleral involvement of nevus of Ota, satisfaction score after surgery, histologic examination, and postoperative complications. Main outcome measures were best-corrected visual acuity (BCVA), induced refractive error, intraocular pressure (IOP), patient satisfaction scores, and anterior segment photographs. RESULTS: All patients showed cosmetic improvement without any serious complications. Preoperative and postoperative BCVA, IOP, and refractive outcomes did not change significantly. CONCLUSIONS: Superficial scleral separation is an effective procedure for cosmetic improvement of oculodermal melanocytosis.
[Mh] Termos MeSH primário: Neoplasias Oculares/cirurgia
Nevo de Ota/cirurgia
Esclera/cirurgia
Esclerostomia/métodos
Neoplasias Cutâneas/cirurgia
[Mh] Termos MeSH secundário: Adolescente
Adulto
Feminino
Seres Humanos
Pressão Intraocular/fisiologia
Masculino
Meia-Idade
Erros de Refração/fisiopatologia
Inquéritos e Questionários
Acuidade Visual/fisiologia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171023
[Lr] Data última revisão:
171023
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160409
[St] Status:MEDLINE
[do] DOI:10.1097/ICL.0000000000000263


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[PMID]:27918003
[Au] Autor:Guss L; Bolton JG; Fabi SG
[Ad] Endereço:Department of Dermatology, Johns Hopkins University, Baltimore, Maryland, USA. lgreenw5@jhu.edu.
[Ti] Título:Combination therapy in skin of color including injectables, laser, and light devices.
[So] Source:Semin Cutan Med Surg;35(4):211-217, 2016 Dec.
[Is] ISSN:1085-5629
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:With the rapid increase in patients seeking cosmetic treatments, the variation in responses of lightly pigmented skin versus darkly pigmented skin has become increasingly apparent. Despite extensive treatment options in patients with skin of color, there is a paucity of well-designed studies performed on this patient population. The lack of research is concerning, as it is well documented that patients with darker skin types are at an increased risk of adverse events when treated with many of the available modalities used in cosmetic procedures. Fortunately, by combining a variety of treatments, these risks may be abrogated, and combination treatments may be a promising regimen for a wide variety of cosmetic complaints. An overview and evaluation of the research of combination therapy in skin of color is presented.
[Mh] Termos MeSH primário: Técnicas Cosméticas
Pigmentação da Pele
[Mh] Termos MeSH secundário: Acne Vulgar/complicações
Cicatriz/etiologia
Cicatriz/terapia
Terapia Combinada
Seres Humanos
Injeções
Terapia a Laser
Melanose/terapia
Nevo de Ota/terapia
Fototerapia
Rejuvenescimento
Envelhecimento da Pele
Neoplasias Cutâneas/terapia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1704
[Cu] Atualização por classe:170406
[Lr] Data última revisão:
170406
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161206
[St] Status:MEDLINE
[do] DOI:10.12788/j.sder.2016.059


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[PMID]:26861980
[Au] Autor:Yu P; Yu N; Diao W; Yang X; Feng Y; Qi Z
[Ad] Endereço:Plastic Surgery Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, 33 Badachu Road, Shijingshan District, Beijing, 100068, China.
[Ti] Título:Comparison of clinical efficacy and complications between Q-switched alexandrite laser and Q-switched Nd:YAG laser on nevus of Ota: a systematic review and meta-analysis.
[So] Source:Lasers Med Sci;31(3):581-91, 2016 Apr.
[Is] ISSN:1435-604X
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Although the application of Q-switched lasers on nevus of Ota (OTA) is well demonstrated, debates about clinical option between Q-switched alexandrite laser (QSA) and Q-switched Nd:YAG laser (QSNY) still remain. This systematic review and meta-analysis estimated the overall successful rate of OTA pigment clearance and complication rate of QSA and QSNY and evaluated which laser could produce a better result. English articles evaluating pigment clearance and complications of QSA and/or QSNY on OTA were screened through predetermined inclusion and exclusion criteria and analyzed. The successful rate of pigment clearance and complication rate of QSA and QSNY were respectively calculated using a random-effects or fixed-effects model, depending on the heterogeneity of the included studies. The successful rate and complication rate of QSA and QSNY were compared statistically. Of the 140 articles searched, 13 met inclusion criteria. Totally, 2153 OTA patients treated by QSA and 316 patients treated by QSNY were analyzed. In QSA and QSNY groups, respectively, the successful rate of OTA pigment clearance was 48.3% (95% confidence interval (CI) 19.9-76.8%) and 41% (95% CI 9.7-72.2%), while the complication rate was 8.0% (95% CI 3.9-12.2%) and 13.4% (95% CI 7.7-19.0%). When compared with QSNY, QSA had a significantly higher successful rate (P = 0.017), and a lower complication rate (P = 0.000). According to this review, QSA may surpass QSNY in treatment for OTA as it had a superior successful rate of pigment clearance and a lower complication rate than QSNY did.
[Mh] Termos MeSH primário: Lasers de Estado Sólido/uso terapêutico
Terapia com Luz de Baixa Intensidade
Nevo de Ota/radioterapia
Neoplasias Cutâneas/radioterapia
[Mh] Termos MeSH secundário: Seres Humanos
Lasers de Estado Sólido/efeitos adversos
Resultado do Tratamento
[Pt] Tipo de publicação:COMPARATIVE STUDY; JOURNAL ARTICLE; META-ANALYSIS; REVIEW
[Em] Mês de entrada:1611
[Cu] Atualização por classe:171013
[Lr] Data última revisão:
171013
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160211
[St] Status:MEDLINE
[do] DOI:10.1007/s10103-016-1885-z


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[PMID]:26808181
[Au] Autor:Yang J; Luo G; Tuyana S; Tong X; Tu Y; Tao J
[Ad] Endereço:*Department of Dermatology, Affiliated Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan City, China; †Department of Anesthesiology, Affiliated Puai Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan City, China.
[Ti] Título:Analysis of 28 Chinese Cases of Bilateral Nevus of Ota and Therapeutic Results With the Q-Switched Alexandrite Laser.
[So] Source:Dermatol Surg;42(2):242-8, 2016 Feb.
[Is] ISSN:1524-4725
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Nevus of Ota is a dermal melanocytic lesion that presents as bluish hyperpigmentation along the first or second branch of the trigeminal nerve. It is common in Asians. However, bilateral involvement is rare. There has been no detailed report on bilateral involvement in Chinese people. OBJECTIVE: To analyze the clinical data on bilateral nevus of Ota in Chinese patients and determine the efficacy of pulsed q-switched alexandrite laser treatment. METHODS: Twenty-eight cases of bilateral nevus of Ota were diagnosed by clinical appearance, and detailed clinical data were collected. A q-switched alexandrite laser was used for treatment. RESULTS: The incidence of bilateral nevus of Ota was 1.4% (28 of 1985). More than 3 regions were involved in most patients (96.4%), and symmetrical lesions were observed in approximately 60% of cases (17 of 28). The lesion was seen at or soon after birth in 15 patients (53.6%); two-thirds of these patients (10 of 15) had ocular or mucosal involvement. The therapeutic results were excellent or good in 17 cases; the group that received more than 3 treatments and age of starting treatment being less than 6 years had better therapeutic results. CONCLUSION: The pulsed q-switched alexandrite laser is an effective treatment, and earlier intervention with more sessions achieves better results.
[Mh] Termos MeSH primário: Lasers de Estado Sólido/uso terapêutico
Nevo de Ota/cirurgia
Neoplasias Cutâneas/cirurgia
[Mh] Termos MeSH secundário: Adolescente
Adulto
Idade de Início
Grupo com Ancestrais do Continente Asiático
Criança
Pré-Escolar
Feminino
Seres Humanos
Lactente
Lasers de Estado Sólido/efeitos adversos
Masculino
Nevo de Ota/etnologia
Nevo de Ota/patologia
Neoplasias Cutâneas/etnologia
Neoplasias Cutâneas/patologia
Fatores de Tempo
Cicatrização
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1606
[Cu] Atualização por classe:160205
[Lr] Data última revisão:
160205
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160126
[St] Status:MEDLINE
[do] DOI:10.1097/DSS.0000000000000607


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[PMID]:26777390
[Au] Autor:Wang B; Xie HF; Tan J; Xie HJ; Xu LY; Ding R; Liu FF; Chen X; Jian D; Li J
[Ad] Endereço:Department of Dermatology, Xiangya Hospital, Central South University, China.
[Ti] Título:Induction of melasma by 1064-nm Q-switched neodymium:yttrium-aluminum-garnet laser therapy for acquired bilateral nevus of Ota-like macules (Hori nevus): A study on related factors in the Chinese population.
[So] Source:J Dermatol;43(6):655-61, 2016 Jun.
[Is] ISSN:1346-8138
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Laser treatment has emerged as a common treatment modality for acquired bilateral nevus of Ota-like macules (ABNOM). To identify the ratio of melasma induction and exacerbation before and after laser therapy for ABNOM and to observe the risk factors related to the induction and exacerbation of melasma by laser therapy, we analyzed related factors of 1268 adult Chinese patients who underwent 1064-nm Q-switched neodymium:yttrium-aluminum-garnet (Nd:YAG) laser (QNYL) treatment using case series and case-control studies. Overall, 24.0% of the ABNOM patients had mixed melasma. Among the ABNOM patients without melasma, after laser therapy the development of melasma was more frequently noted in patients older than 35 years (P < 0.0001), as well in patients whose ABNOM was less than 10 cm(2) (P = 0.027), ABNOM were light (similar to yellow-brown) in color (P = 0.021) and skin types were closer to type IV (P < 0.0001). New melasma lesions also appeared most frequently in the zygomatic region (P < 0.0001). Among the ABNOM patients with melasma, 89.5% experienced worsening of their melasma, irrespective of their related factors above. We concluded that the risk of inducing melasma is great after 1064-nm QNYL treatment in ABNOM patients, and particularly in the patients with both ABNOM and melasma. ABNOM patients should be treated as early as possible and before the age of 35 years.
[Mh] Termos MeSH primário: Lasers de Estado Sólido/efeitos adversos
Terapia com Luz de Baixa Intensidade/efeitos adversos
Melanose/etiologia
Nevo de Ota/radioterapia
[Mh] Termos MeSH secundário: Adolescente
Adulto
Estudos de Casos e Controles
Feminino
Seres Humanos
Masculino
Meia-Idade
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1705
[Cu] Atualização por classe:170526
[Lr] Data última revisão:
170526
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160119
[St] Status:MEDLINE
[do] DOI:10.1111/1346-8138.13193


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[PMID]:26701415
[Au] Autor:Vivancos A; Caratú G; Matito J; Muñoz E; Ferrer B; Hernández-Losa J; Bodet D; Pérez-Alea M; Cortés J; Garcia-Patos V; Recio JA
[Ad] Endereço:Cancer Genomics Group Translational Research Program, Vall dHebron Institute of Oncology-VHIO, Vall dHebron Hospital, Barcelona, Spain.
[Ti] Título:Genetic evolution of nevus of Ota reveals clonal heterogeneity acquiring BAP1 and TP53 mutations.
[So] Source:Pigment Cell Melanoma Res;29(2):247-53, 2016 Mar.
[Is] ISSN:1755-148X
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Melanoma presents molecular alterations based on its anatomical location and exposure to environmental factors. Due to its intrinsic genetic heterogeneity, a simple snapshot of a tumor's genetic alterations does not reflect the tumor clonal complexity or specific gene-gene cooperation. Here, we studied the genetic alterations and clonal evolution of a unique patient with a Nevus of Ota that developed into a recurring uveal-like dermal melanoma. The Nevus of Ota and ulterior lesions contained GNAQ mutations were c-KIT positive, and tumors showed an increased RAS pathway activity during progression. Whole-exome sequencing of these lesions revealed the acquisition of BAP1 and TP53 mutations during tumor evolution, thereby unmasking clonal heterogeneity and allowing the identification of cooperating genes within the same tumor. Our results highlight the importance of studying tumor genetic evolution to identify cooperating mechanisms and delineate effective therapies.
[Mh] Termos MeSH primário: Neoplasias de Cabeça e Pescoço/genética
Nevo de Ota/genética
Neoplasias Cutâneas/genética
Proteína Supressora de Tumor p53/genética
Proteínas Supressoras de Tumor/genética
Ubiquitina Tiolesterase/genética
[Mh] Termos MeSH secundário: Adulto
Feminino
Subunidades alfa Gq-G11 de Proteínas de Ligação ao GTP/genética
Neoplasias de Cabeça e Pescoço/patologia
Seres Humanos
Nevo de Ota/patologia
Neoplasias Cutâneas/patologia
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (GNAQ protein, human); 0 (TP53 protein, human); 0 (Tumor Suppressor Protein p53); 0 (Tumor Suppressor Proteins); EC 3.1.2.15 (BAP1 protein, human); EC 3.4.19.12 (Ubiquitin Thiolesterase); EC 3.6.5.1 (GTP-Binding Protein alpha Subunits, Gq-G11)
[Em] Mês de entrada:1611
[Cu] Atualização por classe:170103
[Lr] Data última revisão:
170103
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:151225
[St] Status:MEDLINE
[do] DOI:10.1111/pcmr.12452


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[PMID]:26563954
[Au] Autor:Shah VV; Bray FN; Aldahan AS; Mlacker S; Nouri K
[Ad] Endereço:Department of Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine, 1475 NW 12th Ave. Suite 2175, Miami, FL, 33136, USA. shahvidhiv@gmail.com.
[Ti] Título:Lasers and nevus of Ota: a comprehensive review.
[So] Source:Lasers Med Sci;31(1):179-85, 2016 Jan.
[Is] ISSN:1435-604X
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Nevus of Ota is a benign dermal melanocytic nevus that typically affects Asian children and women. The nevus presents as unilateral blue-gray hyperpigmented macules and patches scattered along the first and second divisions of the trigeminal nerve. Individuals with nevus of Ota experience emotional and psychosocial distress related to cosmetic disfigurement and often look for treatment options. Unfortunately, even when treated early, lesions of nevus of Ota are still difficult to treat. The use of lasers for the treatment of nevus of Ota lesions has become helpful in the management of dermal nevi. Currently, Q-switched (QS) lasers have been the most studied and demonstrated positive results for treatment of nevus of Ota. The purpose of this review article is to summarize the clinical efficacy and side effects associated with QS lasers and the treatment of nevus of Ota lesions.
[Mh] Termos MeSH primário: Terapia a Laser/métodos
Nevo de Ota/terapia
[Mh] Termos MeSH secundário: Seres Humanos
Terapia a Laser/efeitos adversos
Nevo de Ota/patologia
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Em] Mês de entrada:1610
[Cu] Atualização por classe:171013
[Lr] Data última revisão:
171013
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:151114
[St] Status:MEDLINE
[do] DOI:10.1007/s10103-015-1834-2


  10 / 278 MEDLINE  
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[PMID]:26474418
[Au] Autor:Shin S; Lee JW; Lee Y; Kim DS
[Ad] Endereço:Department of Dermatology, Severance Hospital & Cutaneous Biology Research Institute, Yonsei University College of Medicine, 50 Yonsei-ro, Seodaemun-gu, Seoul, 120-752, Korea.
[Ti] Título:Spontaneous partial regression of naevus of Ota with the development of vitiligo.
[So] Source:Br J Dermatol;174(3):694-5, 2016 Mar.
[Is] ISSN:1365-2133
[Cp] País de publicação:England
[La] Idioma:eng
[Mh] Termos MeSH primário: Dermatoses Faciais/etiologia
Neoplasias Faciais/patologia
Nevo de Ota/patologia
Neoplasias Cutâneas/patologia
Vitiligo/etiologia
[Mh] Termos MeSH secundário: Feminino
Seres Humanos
Meia-Idade
Regressão Neoplásica Espontânea
[Pt] Tipo de publicação:CASE REPORTS; LETTER
[Em] Mês de entrada:1701
[Cu] Atualização por classe:170104
[Lr] Data última revisão:
170104
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:151017
[St] Status:MEDLINE
[do] DOI:10.1111/bjd.14232



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