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  1 / 11186 MEDLINE  
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[PMID]:28453756
[Au] Autor:Hovde Ø; Høivik ML; Henriksen M; Solberg IC; Småstuen MC; Moum BA
[Ad] Endereço:Department of Gastroenterology, Innlandet Hospital Trust, Gjøvik, Norway.
[Ti] Título:Malignancies in Patients with Inflammatory Bowel Disease: Results from 20 Years of Follow-up in the IBSEN Study.
[So] Source:J Crohns Colitis;11(5):571-577, 2017 May 01.
[Is] ISSN:1876-4479
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Background and Aims: Whether patients with inflammatory bowel diseases [IBDs] have increased risk of developing cancer has been debated. The aims of the study were to determine the prevalence of intestinal/extraintestinal cancers in an IBD cohort 20 years after diagnosis and to assess whether these patients had an increased cancer-specific risk compared with a matched control population. Methods: Patients with ulcerative colitis [UC] and Crohn's disease [CD] diagnosed 1990-1993 have been prospectively followed up for 20 years. Follow-up visits were carried out 1, 5, 10, and 20 years after inclusion. Data on all cancer cases, deaths, and causes of death were collected from the Cancer Registry of Norway and from the Norwegian Cause of Death Registry. Results: In all, 756 patients [519 UC and 237 CD] were diagnosed with IBD. Increased risk of cancer was seen in UC patients (hazard ratio [HR] = 1.40, 95% confidence interval [CI] 1.08-1.81, p < 0.01), but not in CD patients [HR = 1.23, 95% CI 0.80-2.03, p = 0.30]. Stratified by gender, our data revealed a statistically increased risk for all cancers only in male UC patients compared with the controls [HR = 1.51, 95% CI 1.08-2.11, p = 0.017]. In both groups breast cancer was seen more often than expected. Conclusions: Male UC patients display an increased risk of development of colorectal cancer and, also all cancers combined, compared with the controls. In both UC and CD, standardized incidence ratio for breast cancer was increased.
[Mh] Termos MeSH primário: Doenças Inflamatórias Intestinais/complicações
Neoplasias Intestinais/epidemiologia
Neoplasias/epidemiologia
[Mh] Termos MeSH secundário: Adolescente
Adulto
Idoso
Idoso de 80 Anos ou mais
Causas de Morte
Criança
Pré-Escolar
Colite Ulcerativa/complicações
Doença de Crohn/complicações
Feminino
Seguimentos
Seres Humanos
Neoplasias Intestinais/etiologia
Masculino
Meia-Idade
Neoplasias/etiologia
Neoplasias/mortalidade
Noruega/epidemiologia
Sistema de Registros
Fatores de Risco
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1803
[Cu] Atualização por classe:180308
[Lr] Data última revisão:
180308
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170429
[St] Status:MEDLINE
[do] DOI:10.1093/ecco-jcc/jjw193


  2 / 11186 MEDLINE  
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[PMID]:29391119
[Au] Autor:Manguso N; Johnson J; Harit A; Nissen N; Mirocha J; Hendifar A; Amersi F
[Ad] Endereço:Division of Surgical Oncology, Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, CA, USA.
[Ti] Título:Prognostic Factors Associated with Outcomes in Small Bowel Neuroendocrine Tumors.
[So] Source:Am Surg;83(10):1174-1178, 2017 Oct 01.
[Is] ISSN:1555-9823
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Small bowel neuroendocrine tumors (SBNET) account for most gastrointestinal neuroendocrine tumors. Patients often present with late-stage disease; however, there is little information regarding factors that contribute to recurrence. Database review identified 301 patients diagnosed with SBNET between 1990 and 2013. Univariate analysis included patients who underwent complete resection. Survival was estimated by the Kaplan-Meier method. A total of 147 patients met study criteria. Average age was 60 years (range 21-91); 49 per cent were male. Thirty-seven (25.3%) patients had laparoscopic resection, and 29 (19.9%) patients had only small bowel disease, whereas 108 (72.6%) had nodal metastasis. Five-year overall and disease-free survival were 97.5 and 73.5 per cent. Forty-seven (32%) patients had recurrence. The recurrence group was more likely to have an open operation (59.6 vs 32%, P < 0.01), mesenteric invasion, or lymphatic metastasis (87.2 vs 67%, P < 0.01) compared with the no-recurrence group. Cox regression analysis showed that variables associated with recurrence included nodal disease (HR 9.06, P = 0.03), lymphovascular invasion (LVI) (3.95, P < 0.01), perineural invasion (PNI) (3.48, P < 0.01), and mesenteric involvement (3.77, P = 0.03). Patients with SBNET presenting with nodal metastasis, mesenteric involvement, LVI, or PNI have a higher risk of recurrence. Closer surveillance should be considered after operative resection.
[Mh] Termos MeSH primário: Neoplasias Intestinais/cirurgia
Intestino Delgado/cirurgia
Recidiva Local de Neoplasia/etiologia
Tumores Neuroendócrinos/cirurgia
[Mh] Termos MeSH secundário: Adulto
Idoso
Idoso de 80 Anos ou mais
Estudos de Casos e Controles
Bases de Dados Factuais
Feminino
Seguimentos
Seres Humanos
Neoplasias Intestinais/diagnóstico
Neoplasias Intestinais/mortalidade
Neoplasias Intestinais/patologia
Masculino
Meia-Idade
Recidiva Local de Neoplasia/mortalidade
Recidiva Local de Neoplasia/patologia
Tumores Neuroendócrinos/diagnóstico
Tumores Neuroendócrinos/mortalidade
Tumores Neuroendócrinos/patologia
Prognóstico
Fatores de Risco
Análise de Sobrevida
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180214
[Lr] Data última revisão:
180214
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180203
[St] Status:MEDLINE


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[PMID]:29390483
[Au] Autor:Kim JH; Yoon HH; Jeong SH; Woo HS; Lee WS; Choi SJ; Kim SG; Ha SY; Kwon KA
[Ad] Endereço:Department of Internal Medicine, Gachon University Gil Medical Center, Gachon University School of Medicine, Incheon.
[Ti] Título:Spontaneous peeled ileal giant lipoma caused by lower gastrointestinal bleeding: A case report.
[So] Source:Medicine (Baltimore);96(51):e9253, 2017 Dec.
[Is] ISSN:1536-5964
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:RATIONALE: Gastrointestinal subepithelial tumors (SETs) with endoscopic features such as ulceration, a red color change, a peeled mucosal layer, and spontaneous bleeding could have malignant potential. However, we encountered a case of a lipoma that presented features different from the generally known features of gastrointestinal SETs. Therefore, we report an interesting rare case of a terminal ileal giant lipoma with a unique feature of spontaneous peeled ulceration on the surface on endoscopy that caused gastrointestinal bleeding. PATIENT: An 82-year-old woman with a 1-week history of abdominal pain and hematochezia presented to our hospital. DIAGNOSES: Ileocolonoscopy revealed a SET with a peeled surface and erythematous and ulcerative mucosal changes as well as exposed a submucosal mass at the terminal ileum. Macroscopically, the lesion appeared as a yellowish pedunculated polypoid mass measuring 3 × 2 cm with a peeled mucosal ulceration. Histopathological findings revealed a submucosal lipoma of the terminal ileum. INTERVENTION: We thought that the endoscopic finding indicated malignant SETs or those with malignant potential rather than benign SETs. Therefore, the patient underwent an elective laparoscopic ileocecectomy. LESSONS: We encountered a lipoma that did not present with the typical features of gastrointestinal SETs. Our findings suggest that clinicians should consider that benign SETs in the terminal ileum may present with various endoscopic findings similar to those of malignant SETs, which can cause fatal symptoms and signs.
[Mh] Termos MeSH primário: Hemorragia Gastrointestinal/etiologia
Íleo/cirurgia
Neoplasias Intestinais/patologia
Laparoscopia/métodos
Lipoma/patologia
[Mh] Termos MeSH secundário: Dor Abdominal/diagnóstico
Dor Abdominal/etiologia
Idoso de 80 Anos ou mais
Endoscopia por Cápsula/métodos
Feminino
Seguimentos
Hemorragia Gastrointestinal/cirurgia
Seres Humanos
Íleo/patologia
Mucosa Intestinal/patologia
Mucosa Intestinal/cirurgia
Neoplasias Intestinais/complicações
Neoplasias Intestinais/diagnóstico por imagem
Neoplasias Intestinais/cirurgia
Lipoma/complicações
Lipoma/diagnóstico por imagem
Lipoma/cirurgia
Medição de Risco
Índice de Gravidade de Doença
Resultado do Tratamento
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE; REVIEW
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180214
[Lr] Data última revisão:
180214
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:180203
[St] Status:MEDLINE
[do] DOI:10.1097/MD.0000000000009253


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[PMID]:28467579
[Au] Autor:Avci T; Yabanoglu H; Arer IM; Koçer NE; Çaliskan K; Börcek P; Ekici Y
[Ad] Endereço:Department of General Surgery, Baskent University Faculty of Medicine, Ankara-Turkey. tevfikavci@yahoo.com.
[Ti] Título:Primary small intestinal non-Hodgkin lymphoma diagnosed after emergency surgery.
[So] Source:Ulus Travma Acil Cerrahi Derg;23(2):128-133, 2017 Mar.
[Is] ISSN:1306-696X
[Cp] País de publicação:Turkey
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: The aim of this study was to investigate clinical manifestation, diagnosis, treatment, and prognosis of patients with primary gastrointestinal non-Hodgkin lymphoma (PGI NHL), whose initial presentation was bowel obstruction or perforation. METHODS: Data of patients who underwent surgical intervention due to radiological evidence of perforation or intestinal obstruction and were subsequently diagnosed with intestinal lymphoma at Baskent University hospitals between January 2007 and November 2014 were examined retrospectively. Medical records, clinical history, symptoms, pathological reports, and treatment modalities were analyzed. RESULTS: Study population comprised 17 patients (8 male, 9 female) with PGI NHL and mean age of 52±20.2 years. Symptoms reported by the patients were abdominal pain, nausea, vomiting, weight loss, and loss of appetite. All 17 patients underwent surgical treatment; 12 also received postoperative chemotherapy. Most common pathological subtype was diffuse large B-cell lymphoma (70.5%). Mean follow-up time was 26 months (range: 1-69 months) and 5-year survival rate was 64.3%. CONCLUSION: Initial presentation of PGI NHL may be obstruction with or without perforation; clinicians and surgeons should keep this in mind while assessing patient with bowel obstruction, and particularly patient in fifth decade of life.
[Mh] Termos MeSH primário: Neoplasias Intestinais
Intestino Delgado/cirurgia
Linfoma não Hodgkin
[Mh] Termos MeSH secundário: Adulto
Idoso
Feminino
Seres Humanos
Neoplasias Intestinais/diagnóstico
Neoplasias Intestinais/epidemiologia
Neoplasias Intestinais/cirurgia
Obstrução Intestinal
Perfuração Intestinal
Linfoma não Hodgkin/diagnóstico
Linfoma não Hodgkin/epidemiologia
Linfoma não Hodgkin/mortalidade
Linfoma não Hodgkin/cirurgia
Masculino
Meia-Idade
Prognóstico
Estudos Retrospectivos
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180209
[Lr] Data última revisão:
180209
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170504
[St] Status:MEDLINE
[do] DOI:10.5505/tjtes.2016.02359


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[PMID]:29176321
[Au] Autor:Li R; Ouyang ZY; Xiao JB; He J; Zhou YW; Zhang GY; Li Q; Gu H; Leng AM; Liu T
[Ad] Endereço:Department of Gastroenterology, Xiangya Hospital of Central South University, Changsha, China.
[Ti] Título:Clinical Characteristics and Prognostic Factors of Small Intestine Angiosarcoma: a Retrospective Clinical Analysis of 66 Cases.
[So] Source:Cell Physiol Biochem;44(2):817-827, 2017.
[Is] ISSN:1421-9778
[Cp] País de publicação:Switzerland
[La] Idioma:eng
[Ab] Resumo:BACKGROUND/AIMS: Primary angiosarcoma of the small intestine is a rare neoplasia, and there are limited data from systematic analyses. The aim of this study is to describe the clinical and pathological characteristics in addition to the prognostic factors for this rare neoplasia. METHODS: We retrospectively collected the clinical records and prognostic information of 66 patients with small intestine angiosarcoma reported between 1970 and 2017. We used the Chi-square test, the log-rank test, and Cox regression analyses to evaluate the data. RESULTS: There were 66 patients diagnosed with small intestine angiosarcoma. The onset age ranged from 24-92 years old. There were 24 patients diagnosed before the year 2000, and 42 patients were diagnosed after 2000. The data indicated that 49 cases were diagnosed as primary disease, and the remaining 15 cases were secondary disease. The main clinical symptoms were nonspecific and included gastrointestinal (GI) bleeding and abdominal pain. Additionally, we found multi-center foci were one of the characteristics of this disease. Radiation-induced small intestine angiosarcoma (RSIA) is a special type of disease with a similar prognosis. This type was more frequent in females and decreased after the year 2000. We also found that GI bleeding was less common in RSIA cases. The log-rank test results revealed that old-age, poor differentiation, and GI bleeding were associated with worse prognosis. Surgical treatment showed a trend toward a prolonged survival time. However, the result was not statistically significant. Our results show treatment with adjuvant therapy improved prognosis. The multivariate Cox analysis demonstrated adjuvant therapy was an independent indicator of a favorable outcome in small intestine angiosarcoma patients. CONCLUSION: Pay attention to the unexplained gastrointestinal bleeding could lead to a faster diagnosis and control of small intestine angiosarcoma. Furthermore, treatments including adjuvant therapy can effectively improve the prognosis.
[Mh] Termos MeSH primário: Hemangiossarcoma/diagnóstico
Neoplasias Intestinais/diagnóstico
[Mh] Termos MeSH secundário: Adulto
Idoso
Idoso de 80 Anos ou mais
Quimioterapia Adjuvante
Bases de Dados Factuais
Feminino
Hemorragia Gastrointestinal
Hemangiossarcoma/mortalidade
Hemangiossarcoma/terapia
Seres Humanos
Neoplasias Intestinais/mortalidade
Neoplasias Intestinais/terapia
Estimativa de Kaplan-Meier
Masculino
Meia-Idade
Prognóstico
Modelos de Riscos Proporcionais
Estudos Retrospectivos
Fatores Sexuais
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1801
[Cu] Atualização por classe:180118
[Lr] Data última revisão:
180118
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171128
[St] Status:MEDLINE
[do] DOI:10.1159/000485345


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[PMID]:29245282
[Au] Autor:Won YG; Seo KJ; Hyeon J; Shin OR; Chang E; Sun S; Won HS; Ko YH; Na SJ; Lee SL; Ku YM; Lee DS
[Ad] Endereço:aDepartment of Radiation OncologybDepartment of Hospital PathologycDivision of Oncology, Department of Internal MedicinedDepartment of Radiology, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.
[Ti] Título:Gastroenteropancreatic-origin neuroendocrine carcinomas: Three case reports with favorable responses following localized radiotherapy and a review of literature.
[So] Source:Medicine (Baltimore);96(49):e9009, 2017 Dec.
[Is] ISSN:1536-5964
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:RATIONALE: The radiotherapy (RT) responses of gastroenteropancreatic (GEP)-origin neuroendocrine tumors remain unclear. We report cases of favorable response after localized RT of GEP-origin neuroendocrine carcinomas (GEP-NECs). PATIENT CONCERNS: 1. An 82-year-old male presented with a lower esophageal mass. Positron emission tomography computed tomography (PET-CT) scan showed a lower esophageal mass and gastrohepatic lymph nodes. 2. A 52-year-old female presented with abdominal discomfort. CT scan showed a 9.8 cm-sized enhancing mass in the lesser sac abutting the stomach, pancreas and liver. 3. A 54-year-old male patient presented with anal pain and bleeding. CT scan showed a remnant mass in the perirectal area after trans-anal excision. DIAGNOSES: The diagnoses of GEP-NECs were pathologically confirmed by biopsy or excision, and immunohistochemical stainings of Ki-67, CD56, synaptophysin and chromogranin-A. INTERVENTIONS: 1. The patient was treated with definitive RT. 2. The patient was treated with RT after two cycles of etoposide-cisplatin chemotherapy. 3. The patient was treated with adjuvant RT. OUTCOMES: 1. Complete remission was achieved based on CT scan four months after RT. 2. CT scan showed partial regression of the mass with a 5 cm-diameter at six months after RT. Adjuvant chemotherapy was administered after RT. 3. The residual mass was almost completely regressed at CT scan four months after RT. LESSONS: In cases of GEP-NECs, RT can be a useful treatment modality with favorable tumor response for patients with inoperable conditions or those suffering from bulky tumor masses.
[Mh] Termos MeSH primário: Neoplasias Intestinais/patologia
Neoplasias Intestinais/radioterapia
Tumores Neuroendócrinos/patologia
Tumores Neuroendócrinos/radioterapia
Neoplasias Pancreáticas/patologia
Neoplasias Pancreáticas/radioterapia
Neoplasias Gástricas/patologia
Neoplasias Gástricas/radioterapia
[Mh] Termos MeSH secundário: Idoso de 80 Anos ou mais
Quimiorradioterapia Adjuvante/métodos
Feminino
Seres Humanos
Neoplasias Intestinais/diagnóstico
Neoplasias Intestinais/terapia
Masculino
Meia-Idade
Tumores Neuroendócrinos/diagnóstico
Tumores Neuroendócrinos/terapia
Neoplasias Pancreáticas/diagnóstico
Neoplasias Pancreáticas/terapia
Tomografia Computadorizada com Tomografia por Emissão de Pósitrons
Neoplasias Gástricas/diagnóstico
Neoplasias Gástricas/terapia
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Em] Mês de entrada:1801
[Cu] Atualização por classe:180105
[Lr] Data última revisão:
180105
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:171217
[St] Status:MEDLINE
[do] DOI:10.1097/MD.0000000000009009


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[PMID]:29206015
[Au] Autor:Knab LM; Yang A
[Ti] Título:Gastric and Small Bowel Tumors.
[So] Source:Cancer Treat Res;168:1-16, 2016.
[Is] ISSN:0927-3042
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:The incidence of gastric adenocarcinoma has decreased in the United States over the past 70 years although it continues to have a poor prognosis. While radical resection was initially the primary treatment for adenocarcinoma of the stomach, systemic chemotherapy and radiation have been shown to play a role in prolonging survival in most patient populations. This chapter explores the evidence that guides treatment for gastric cancer today. It also discusses the treatment for gastrointestinal stromal tumors (GIST), and small bowel tumors. In addition to systemic therapies, this chapter explores the surgical management of gastric and small bowel tumors including the extent of the gastric lymph node dissection.
[Mh] Termos MeSH primário: Adenocarcinoma/terapia
Neoplasias Intestinais/terapia
Neoplasias Gástricas/terapia
[Mh] Termos MeSH secundário: Mucosa Gástrica/cirurgia
Tumores do Estroma Gastrointestinal/terapia
Seres Humanos
Excisão de Linfonodo
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Em] Mês de entrada:1712
[Cu] Atualização por classe:171221
[Lr] Data última revisão:
171221
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171206
[St] Status:MEDLINE


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[PMID]:29187943
[Au] Autor:Bellamlih H; Bouimetarhan L; Amil T; En-Nouali H; Chouaib N; Jidane S; Rafai M; Belkouch A; Belyamani L
[Ad] Endereço:Service d'Imagerie Médicale, Hôpital Militaire Mohamed V, Faculté de Médecine et de Pharmacie, Rabat, Maroc.
[Ti] Título:[Rare digestive tumors: gastrointestinal stromal tumors (GISTs): about a case of small bowel location and literature review].
[Ti] Título:Tumeurs digestives rares: tumeur gastro-intestinale stromale (GIST): à propos d'un cas de localisation grêlique et revue de littérature..
[So] Source:Pan Afr Med J;27:274, 2017.
[Is] ISSN:1937-8688
[Cp] País de publicação:Uganda
[La] Idioma:fre
[Ab] Resumo:Gastrointestinal stromal tumors (GISTs) are a rare group of mesenchymal tumors mainly occurring in the gastrointestinal tract. Previously, GISTs were classified as smooth muscle tumors also known as leiomyomas, leiomyosarcomas or leiomyoblastomas. However, since the advent of immunohistochemistry, GISTs have been diagnosed on the basis of the identification of c-kit-positive cells. We here report a case of stromal tumor of the small intestine in order to analyze it in the light of literature data and imaging results, which may suggest prebiopsy diagnosis as well as its therapeutic and prognostic peculiarities.
[Mh] Termos MeSH primário: Tumores do Estroma Gastrointestinal/diagnóstico
Neoplasias Intestinais/diagnóstico
Intestino Delgado/patologia
[Mh] Termos MeSH secundário: Feminino
Tumores do Estroma Gastrointestinal/patologia
Seres Humanos
Imuno-Histoquímica
Neoplasias Intestinais/patologia
Meia-Idade
Prognóstico
Proteínas Proto-Oncogênicas c-kit/análise
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE; REVIEW
[Nm] Nome de substância:
EC 2.7.10.1 (Proto-Oncogene Proteins c-kit)
[Em] Mês de entrada:1712
[Cu] Atualização por classe:171219
[Lr] Data última revisão:
171219
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171201
[St] Status:MEDLINE
[do] DOI:10.11604/pamj.2017.27.274.12708


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[PMID]:29049187
[Au] Autor:Wang P; Li Q; Zhang L; Ji H; Zhang CZ; Wang B
[Ad] Endereço:aShandong Medical Imaging Research Institute, School of Medicine, Shandong University, Jinan bDepartment of Radiology cDepartment of Pathology, The Affiliated Hospital of Binzhou Medical University, School of Medicine, Binzhou Medical University, Binzhou dMedical Imaging Research Institute, Department of Radiology, School of Medicine, Binzhou Medical University, Yantai, Shandong, China.
[Ti] Título:A myeloid sarcoma involving the small intestine, kidneys, mesentery, and mesenteric lymph nodes: A case report and literature review.
[So] Source:Medicine (Baltimore);96(42):e7934, 2017 Oct.
[Is] ISSN:1536-5964
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:RATIONALE: Myeloid sarcomas (MSs) are rare malignant hematological tumors. They most commonly occur in patients with acute or chronic myeloid leukemia. A de novo MS with no evidence of blood system disease is rare, but may represent the first sign of a systemic illness that precedes a full-blown disease. Herein, we report the computed tomography (CT) findings of an extremely rare case of a nonleukemic MS that progressed to acute myelogenous leukemia (AML) and simultaneously involved the small intestine, kidneys, mesentery, and mesenteric lymph nodes. Moreover, we provide CT findings before and after AML chemotherapy, which have not been reported previously. PATIENT CONCERNS: A 25-year-old man with intermittent upper abdominal pain for 6 months was admitted to the hospital on November 28, 2015. Initial CT showed concentric wall thickening of the jejunum with an adjacent mesenteric soft tissue mass and mesenteric lymph nodes enlargement. Both kidneys were involved as indicated by the presence of well-defined mildly dilated lesions. During the laparoscopic surgery, the small intestinal tumor, mesenteric soft tissue mass, and mesenteric lymph nodes were removed. DIAGNOSES: The pathological diagnosis was an MS. INTERVENTIONS: The patient refused systemic chemotherapy and was rehospitalized with persistently aggravated abdominal distension on February 17, 2016. Follow-up CT showed diffuse small bowel wall thickening, widespread infiltration of the peritoneum, omentum, and mesentery, mesenteric lymph node enlargement, and large amounts of ascites fluid. The lesions in both kidneys were substantially larger and more numerous than on initial CT. Then the patient was treated with conventional AML chemotherapy. OUTCOMES: The patient achieved complete hematological remission on bone marrow examination. Follow-up CT in September 4, 2016, showed none of the abnormalities seen on initial CT. Currently, the patient is in complete remission. LESSONS: If the radiological examination shows lesions at multiple sites, and these lesions are soft tissue masses with homogenous enhancement, MS should be considered in the differential diagnosis, and an aspiration biopsy should be performed to provide a definitive pathological diagnosis. If MS is diagnosed, systemic chemotherapy is crucial to recovery; otherwise, the disease may progress rapidly. Medical imaging is helpful for diagnosing MS and for monitoring treatment response.
[Mh] Termos MeSH primário: Neoplasias Intestinais/patologia
Neoplasias Renais/patologia
Neoplasias Primárias Múltiplas/patologia
Neoplasias Peritoneais/patologia
Sarcoma Mieloide/patologia
[Mh] Termos MeSH secundário: Dor Abdominal/diagnóstico
Dor Abdominal/etiologia
Adulto
Diagnóstico Diferencial
Seres Humanos
Neoplasias Intestinais/diagnóstico por imagem
Intestino Delgado/patologia
Rim/patologia
Neoplasias Renais/diagnóstico por imagem
Linfonodos/patologia
Masculino
Mesentério/patologia
Neoplasias Primárias Múltiplas/diagnóstico por imagem
Neoplasias Peritoneais/diagnóstico por imagem
Sarcoma Mieloide/diagnóstico por imagem
Tomografia Computadorizada por Raios X/métodos
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE; REVIEW
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171122
[Lr] Data última revisão:
171122
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:171020
[St] Status:MEDLINE
[do] DOI:10.1097/MD.0000000000007934


  10 / 11186 MEDLINE  
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[PMID]:28991566
[Au] Autor:Kim JS; Park SH; Hansel S; Fletcher JG
[Ad] Endereço:Department of Radiology and Research Institute of Radiology, University of Ulsan College of Medicine, Asan Medical Center, 88, Olympic-ro 43-gil, Songpa-gu, Seoul 05505, South Korea.
[Ti] Título:Imaging and Screening of Cancer of the Small Bowel.
[So] Source:Radiol Clin North Am;55(6):1273-1291, 2017 Nov.
[Is] ISSN:1557-8275
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Delayed diagnosis of small bowel cancers frequently occurs and may arise because of many factors, including low incidence of disease, difficult endoscopic access, lack of mucosal mass or abnormality, subtle radiologic features, and low index of clinical suspicion. As small bowel cancers are rare and their causes are largely unknown, routine population-based screening of asymptomatic patients to find precursor lesions or early cancers is ineffective. However, targeted screening/surveillance strategies are used in specific at-risk and symptomatic patient populations. This article reviews issues regarding early diagnosis of small bowel cancers, with focus on state-of-the-art cross-sectional imaging techniques.
[Mh] Termos MeSH primário: Neoplasias Intestinais/diagnóstico por imagem
Intestino Delgado/diagnóstico por imagem
Imagem por Ressonância Magnética/métodos
Tomografia Computadorizada por Raios X/métodos
[Mh] Termos MeSH secundário: Seres Humanos
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Em] Mês de entrada:1711
[Cu] Atualização por classe:171102
[Lr] Data última revisão:
171102
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:171010
[St] Status:MEDLINE



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