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[PMID]:29484748
[Au] Autor:Peurala E; Tuominen M; Löyttyniemi E; Syrjänen S; Rautava J
[Ad] Endereço:Department of Oral Pathology and Oral Radiology, Institute of Dentistry, Faculty of Medicine, University of Turku, Turku, Finland.
[Ti] Título:Eosinophilia is a favorable prognostic marker for oral cavity and lip squamous cell carcinoma.
[So] Source:APMIS;126(3):201-207, 2018 Mar.
[Is] ISSN:1600-0463
[Cp] País de publicação:Denmark
[La] Idioma:eng
[Ab] Resumo:Eosinophils are frequently encountered with squamous cell carcinomas (SCC) and it has been proposed that tumor-associated tissue eosinophilia (TATE) could be of prognostic significance in oral SCC. The aim was to evaluate TATE in 83 oral cavity and 16 lip SCCs as well as the best possible use of TATE as a prognostic marker. The number of eosinophils was counted per high power fields (HPF, ×400) in three different representative areas of the tumor and its stroma. The degree of TATE was analyzed in relation to clinicopathological features of tumors and patients' survival (follow-up mean 40.7 months) using Fisher's exact test. TATE was detected in 58 (70%) oral and 8 (50%) lip SCC samples. The median number of eosinophils between oral and lip SCC was different (p = 0.028) but TATE was similar per HPF (p = 0.085). Totally, 6% of lip and 21% of oral SCC patients died during the follow-up. The patients with the higher TATE had significantly better survival than the patients with the lower TATE (p = 0.0136). The best cut-off value predicting the survival was 4 eosinophils/HPF. TATE is a prognostic marker for oral and lip SCC: more than 4 eosinophils/HPF may predict more favorable prognosis.
[Mh] Termos MeSH primário: Carcinoma de Células Escamosas/patologia
Eosinofilia/patologia
Eosinófilos/patologia
Neoplasias Labiais/patologia
Lábio/patologia
[Mh] Termos MeSH secundário: Adulto
Idoso
Idoso de 80 Anos ou mais
Consumo de Bebidas Alcoólicas/efeitos adversos
Biomarcadores Tumorais/metabolismo
Carcinoma de Células Escamosas/mortalidade
Intervalo Livre de Doença
Eosinófilos/citologia
Feminino
Seres Humanos
Contagem de Leucócitos
Neoplasias Labiais/mortalidade
Masculino
Meia-Idade
Estudos Retrospectivos
Fumar/efeitos adversos
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Biomarkers, Tumor)
[Em] Mês de entrada:1803
[Cu] Atualização por classe:180309
[Lr] Data última revisão:
180309
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180228
[St] Status:MEDLINE
[do] DOI:10.1111/apm.12809


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[PMID]:28467525
[Au] Autor:Uribe P; Collgros H; Scolyer RA; Menzies SW; Guitera P
[Ad] Endereço:Department of Dermatology, Facultad de Medicina, Pontificia Universidad Catolica de Chile, Santiago, Chile.
[Ti] Título:In Vivo Reflectance Confocal Microscopy for the Diagnosis of Melanoma and Melanotic Macules of the Lip.
[So] Source:JAMA Dermatol;153(9):882-891, 2017 Sep 01.
[Is] ISSN:2168-6084
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Importance: Benign melanotic macules (MAC) are the most frequent cause of lip pigmentation and sometimes difficult to differentiate from lip melanoma (MEL). Objectives: To report in vivo reflectance confocal microscopy (RCM) features of normal lips of different phototypes and to identify features that assist in distinguishing MEL from MAC using dermoscopy and RCM. Design, Setting, and Participants: For this retrospective observational study, 2 groups of patients from 2 tertiary referral centers for melanoma (Sydney Melanoma Diagnostic Centre and Melanoma Institute Australia) were recruited between June 2007 and January 2015. Group 1 included patients with normal lips and different phototypes, and Group 2 consisted of patients with MAC and MEL; RCM and dermoscopy were used for lips analysis. Main Outcomes and Measures: Overall, 92 RCM features were correlated with clinical history, dermoscopic images, and histopathology in all patients with MEL and 5 patients with MAC. Results: Images from the vermillion and/or mucosal part of the lip were recorded from 10 patients with clinically normal lips (mean [SD] age, 34.5 [6.1] years), 16 patients with MAC (mean [SD] age, 49.6 [17.9] years), and 5 patients with 6 cases of MEL (1 patient had a recurrent lesion; mean [SD] age, 56.2 [15.5] years). In normal lips, the draped pattern-a previously described MAC RCM feature-was identified in all cases. In MEL, the following findings were frequent and significantly different from MAC: epidermal disarray; pagetoid infiltration of dendritic and/or round cells; a nonspecific architectural pattern at the dermoepidermal junction (DEJ); nonhomogenously distributed papillae; continuous (lentiginous) proliferation of cells with marked atypia at the DEJ, especially in interpapillary spaces; a higher number of dendritic cells (especially roundish); and atypical round cells at the DEJ. The cellular body area of dendritic cells was about the double in MEL compared with MAC. An RCM lip algorithm was developed that provided 100% sensitivity and 88% specificity for the diagnosis of MEL of the vermillion and mucosal part of the lip. With dermoscopy, MAC were correctly classified as benign in 13 of 16 cases (81%) and MEL were classified as equivocal or malignant in 5 of 6 cases (83%). Conclusions and Relevance: Reflectance confocal microscopy can assist in the differential diagnosis of lip MEL and MAC. An RCM Lip Score that we developed based on study results is proposed and needs to be validated on an independent data set.
[Mh] Termos MeSH primário: Dermoscopia
Neoplasias Labiais/patologia
Melanoma/patologia
Melanose/patologia
Microscopia Confocal
[Mh] Termos MeSH secundário: Adulto
Diagnóstico Diferencial
Feminino
Seres Humanos
Lábio
Masculino
Meia-Idade
Estudos Retrospectivos
[Pt] Tipo de publicação:JOURNAL ARTICLE; MULTICENTER STUDY; OBSERVATIONAL STUDY
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171207
[Lr] Data última revisão:
171207
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:170504
[St] Status:MEDLINE
[do] DOI:10.1001/jamadermatol.2017.0504


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[PMID]:28913905
[Au] Autor:Tseng HW; Liou HH; Tsai KW; Ger LP; Shiue YL
[Ad] Endereço:Department of Dermatology, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan.
[Ti] Título:Clinicopathological study of lip cancer: a retrospective hospital-based study in Taiwan.
[So] Source:APMIS;125(11):1007-1016, 2017 Nov.
[Is] ISSN:1600-0463
[Cp] País de publicação:Denmark
[La] Idioma:eng
[Ab] Resumo:To evaluate the clinicopathological characteristics, high-risk lifestyle factors (HRLF: chronic exposure to sun, betel quid, alcohol, and tobacco), and prognostic factors of lip cancer. The hospital records of patients with pathologically confirmed lip squamous cell carcinoma (LSCC, n = 112) and lip basal cell carcinoma (LBCC, n = 21) were reviewed. Differences in clinicopathological characteristics between LSCC and LBCC, upper and lower lip, and status of second primary tumors were compared by chi-square test and logistic regression. The prognostic factors for LSCC were analyzed by Cox regression. Compared with LBCC patients, LSCC patients were men-predominant (p < 0.001), had younger ages at onset (p < 0.001), and higher rates of lower lips involvement (p < 0.001) and HRLFs. Patients with second primary tumors were highly associated with lower lip cancer involvement (adjusted odds ratio = 2.91, p = 0.03). Patients with lower lip cancer had more HRLFs with an increasing linear trend (p = 0.004). The poorer prognostic factors of LSCC for disease-specific survival were advanced stage III/IV [crude hazard ratio (CHR) = 11.16, p < 0.001], tumor dimension >4 cm (CHR = 8.19, p = 0.006), lymph node involvement (CHR = 11.48, p < 0.001), and recurrence (CHR = 3.96, p = 0.01); whereas for disease-free survival were moderately to poorly differentiated LSCC (CHR = 4.97, p = 0.002) and alcohol consumption (CHR = 3.13, p = 0.04). LSCC and lower lip cancer were highly associated with HRLFs.
[Mh] Termos MeSH primário: Carcinoma Basocelular/diagnóstico
Carcinoma de Células Escamosas/diagnóstico
Neoplasias Labiais/diagnóstico
Recidiva Local de Neoplasia/diagnóstico
Assunção de Riscos
[Mh] Termos MeSH secundário: Adulto
Fatores Etários
Idoso
Idoso de 80 Anos ou mais
Consumo de Bebidas Alcoólicas/efeitos adversos
Carcinoma Basocelular/etiologia
Carcinoma Basocelular/mortalidade
Carcinoma Basocelular/patologia
Carcinoma de Células Escamosas/etiologia
Carcinoma de Células Escamosas/mortalidade
Carcinoma de Células Escamosas/patologia
Feminino
Seres Humanos
Luz/efeitos adversos
Neoplasias Labiais/etiologia
Neoplasias Labiais/mortalidade
Neoplasias Labiais/patologia
Masculino
Meia-Idade
Recidiva Local de Neoplasia/etiologia
Recidiva Local de Neoplasia/mortalidade
Recidiva Local de Neoplasia/patologia
Prognóstico
Modelos de Riscos Proporcionais
Estudos Retrospectivos
Fatores de Risco
Fatores Sexuais
Taiwan
Uso de Tabaco/efeitos adversos
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1711
[Cu] Atualização por classe:171101
[Lr] Data última revisão:
171101
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170916
[St] Status:MEDLINE
[do] DOI:10.1111/apm.12751


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[PMID]:28829344
[Au] Autor:Wu-Fienberg Y; Bordeaux JS
[Ad] Endereço:*Department of Plastic Surgery, University Hospitals Case Medical Center, Cleveland, Ohio;†Department of Dermatology, Case Western Reserve University School of Medicine, Cleveland, Ohio.
[Ti] Título:Repair of a Large, Full-Thickness Defect of the Lower Lip Under Local Anesthesia.
[So] Source:Dermatol Surg;43(9):1176-1179, 2017 09.
[Is] ISSN:1524-4725
[Cp] País de publicação:United States
[La] Idioma:eng
[Mh] Termos MeSH primário: Carcinoma de Células Escamosas/cirurgia
Neoplasias Labiais/cirurgia
Cirurgia de Mohs
Procedimentos Cirúrgicos Reconstrutivos
[Mh] Termos MeSH secundário: Idoso
Seres Humanos
Masculino
Retalhos Cirúrgicos
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171012
[Lr] Data última revisão:
171012
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170823
[St] Status:MEDLINE
[do] DOI:10.1097/DSS.0000000000000784


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[PMID]:28807064
[Au] Autor:Eskiizmir G; Ozgur E; Karaca G; Temiz P; Yanar NH; Ozyurt BC
[Ad] Endereço:Department of Otolaryngology - Head and Neck Surgery,Celal Bayar University,Manisa,Turkey.
[Ti] Título:Stage is a prognostic factor for surgically treated patients with early-stage lip cancer for whom a 'wait and see' policy in terms of neck status has been implemented.
[So] Source:J Laryngol Otol;131(10):889-894, 2017 Oct.
[Is] ISSN:1748-5460
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:OBJECTIVES: To determine the locoregional control and survival rates (in terms of risk factors) of patients who underwent surgical resection of early-stage lip cancer and for whom a 'wait and see' policy in terms of neck status had been implemented. METHODS: The sociodemographic data, tumour stage, tumour characteristics and histopathological features of 41 patients with early-stage lip cancer were evaluated. Factors predictive of survival and locoregional recurrence were analysed. The five-year overall survival and disease-free survival rates were determined, and the prognostic risk factors were compared. RESULTS: The mean follow-up period was 60.5 months (range, 4-92 months). Age, sex, tumour stage, tumour thickness and volume, and perineural involvement were not predictive of locoregional recurrence or survival. Pathological tumour stage (T1 vs T2) was a prognostic factor for both five-year overall survival (87.3 vs 65.6 per cent, p = 0.042) and disease-free survival (88.6 vs 65.6 per cent, p = 0.037). CONCLUSION: Tumour stage was clearly a major factor affecting the prognosis of surgically treated patients with early-stage lip cancer for whom a 'wait and see' policy in terms of neck status had been implemented.
[Mh] Termos MeSH primário: Neoplasias Labiais/cirurgia
Esvaziamento Cervical/métodos
Pescoço/patologia
[Mh] Termos MeSH secundário: Adulto
Idoso
Idoso de 80 Anos ou mais
Intervalo Livre de Doença
Feminino
Seres Humanos
Neoplasias Labiais/patologia
Masculino
Meia-Idade
Pescoço/cirurgia
Estadiamento de Neoplasias
Prognóstico
Análise de Sobrevida
Resultado do Tratamento
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171010
[Lr] Data última revisão:
171010
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:170816
[St] Status:MEDLINE
[do] DOI:10.1017/S0022215117001669


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[PMID]:28538893
[Au] Autor:Husein-ElAhmed H; Armijo-Lozano R
[Ad] Endereço:Department of Dermatology, Hospital de Baza - Granada, Spain.
[Ti] Título:Lower lip reconstruction using a skin-mucosa Abbe-Estlander flap after squamous cell carcinoma excision.
[So] Source:An Bras Dermatol;92(2):260-262, 2017 Mar-Apr.
[Is] ISSN:1806-4841
[Cp] País de publicação:Brazil
[La] Idioma:eng
[Ab] Resumo:Lips are structures that play an essential role in aesthetics and in different functions such as nutrition and speech. The complex anatomy of the lips - with three different layers composed of skin, mucosa, and muscles - makes surgical management of this area a therapeutic challenge. The use of flaps for the reconstruction of large defects with low risk of necrosis is possible given the abundant blood supply of the lips. We report a case of surgical reconstruction of the lower lip after the excision of a severe squamous cell carcinoma using a skin-mucosa Abbe-Estlander flap with a satisfactory final outcome.
[Mh] Termos MeSH primário: Carcinoma de Células Escamosas/cirurgia
Neoplasias Labiais/cirurgia
Lábio/cirurgia
Procedimentos Cirúrgicos Reconstrutivos/métodos
Retalhos Cirúrgicos/cirurgia
[Mh] Termos MeSH secundário: Idoso
Estética
Seres Humanos
Masculino
Membrana Mucosa
[Pt] Tipo de publicação:CASE REPORTS
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171006
[Lr] Data última revisão:
171006
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170525
[St] Status:MEDLINE


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[PMID]:28480532
[Au] Autor:Pottegård A; Hallas J; Olesen M; Svendsen MT; Habel LA; Friedman GD; Friis S
[Ad] Endereço:Clinical Pharmacology and Pharmacy, Department of Public Health, University of Southern Denmark, Odense, Denmark.
[Ti] Título:Hydrochlorothiazide use is strongly associated with risk of lip cancer.
[So] Source:J Intern Med;282(4):322-331, 2017 Oct.
[Is] ISSN:1365-2796
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: The diuretic hydrochlorothiazide is amongst the most frequently prescribed drugs in the United States and Western Europe, but there is suggestive evidence that hydrochlorothiazide use increases the risk of lip cancer. OBJECTIVES: To study the association between use of hydrochlorothiazide and squamous cell carcinoma of the lip. METHODS: We conducted a case-control study using Danish nationwide registry data. From the Cancer Registry (2004-2012), we identified 633 case patients with squamous cell carcinoma (SCC) of the lip and matched them to 63 067 population controls using a risk-set sampling strategy. Hydrochlorothiazide use (1995-2012) was obtained from the Prescription Registry and defined according to cumulative use. Applying conditional logistic regression, we calculated odds ratios (ORs) for SCC lip cancer associated with hydrochlorothiazide use, adjusting for predefined potential confounders obtained from demographic, prescription and patient registries. RESULTS: Ever-use of hydrochlorothiazide was associated with an adjusted OR for SCC lip cancer of 2.1 (95% confidence interval (CI): 1.7-2.6), increasing to 3.9 (95%CI: 3.0-4.9) for high use (≥25 000 mg). There was a clear dose-response effect (P < 0.001), with the highest cumulative dose category of hydrochlorothiazide (≥100 000 mg) presenting an OR of 7.7 (95%CI: 5.7-10.5). No association with lip cancer was seen with use of other diuretics or nondiuretic antihypertensives. Assuming causality, we estimated that 11% of the SCC lip cancer cases could be attributed to hydrochlorothiazide use. CONCLUSIONS: Hydrochlorothiazide use is strongly associated with an increased risk of lip cancer.
[Mh] Termos MeSH primário: Carcinoma de Células Escamosas/induzido quimicamente
Diuréticos/efeitos adversos
Hidroclorotiazida/efeitos adversos
Neoplasias Labiais/induzido quimicamente
[Mh] Termos MeSH secundário: Idoso
Idoso de 80 Anos ou mais
Carcinoma de Células Escamosas/epidemiologia
Estudos de Casos e Controles
Dinamarca/epidemiologia
Relação Dose-Resposta a Droga
Feminino
Seres Humanos
Neoplasias Labiais/epidemiologia
Modelos Logísticos
Masculino
Meia-Idade
Sistema de Registros
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Diuretics); 0J48LPH2TH (Hydrochlorothiazide)
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170922
[Lr] Data última revisão:
170922
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170509
[St] Status:MEDLINE
[do] DOI:10.1111/joim.12629


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[PMID]:28477445
[Au] Autor:Aksam E; Demirseren ME; Aksam B; Demirseren DD; Inan HM
[Ad] Endereço:Assistant Professor, Plastic Reconstructive and Aesthetic Surgery Department, Izmir Katip Celebi University, Izmir, Turkey. Electronic address: ersinaksam@gmail.com.
[Ti] Título:Sphincter-Sparing Excision and Reconstruction Using Facial Artery Perforator Flaps for Lower Lip Carcinoma.
[So] Source:J Oral Maxillofac Surg;75(8):1792.e1-1792.e8, 2017 Aug.
[Is] ISSN:1531-5053
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:PURPOSE: This article discusses the results of orbicularis oris muscle-sparing surgery and reconstruction of defects through the use of facial artery perforator flaps and mucosal advancement flaps. PATIENTS AND METHODS: Patients with lower lip carcinoma were evaluated retrospectively. Patients who underwent reconstruction with facial artery perforator flaps and mucosal advancement flaps with clear surgical margins and no muscle invasion were included in this study. Frozen section examinations were performed intraoperatively. Patients with muscle invasion were excluded. RESULTS: Between 2005 and 2015, 42 patients were treated by the described method. Supraomohyoid lymph node dissections were performed in patients whose ultrasonography had detected suspicious lymph nodes (n = 4). No metastases were identified on pathologic examination of the lymph nodes, and no local or distant recurrences were seen during a mean follow-up time of 58.4 months (range, 16 to 82 months). CONCLUSIONS: The value of resecting the orbicularis oris muscle in cases in which there has been no muscle invasion is an ongoing subject of debate among surgeons. Preserving the muscle means preserving the function, and this is the main purpose of reconstruction. Using facial artery perforator flaps for reconstruction ensures good esthetic results while also maintaining the maximum oral opening. Sphincter-sparing excision and reconstruction with facial artery perforator flaps comprise a safe and reliable treatment method for selected cases involving lower lip carcinomas.
[Mh] Termos MeSH primário: Neoplasias Labiais/cirurgia
Microcirurgia/métodos
Retalho Perfurante/cirurgia
Procedimentos Cirúrgicos Reconstrutivos/métodos
[Mh] Termos MeSH secundário: Idoso
Idoso de 80 Anos ou mais
Artérias/cirurgia
Feminino
Seres Humanos
Lábio/patologia
Lábio/cirurgia
Neoplasias Labiais/patologia
Excisão de Linfonodo/métodos
Masculino
Meia-Idade
Mucosa Bucal/cirurgia
Estudos Retrospectivos
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170915
[Lr] Data última revisão:
170915
[Sb] Subgrupo de revista:AIM; D; IM
[Da] Data de entrada para processamento:170507
[St] Status:MEDLINE


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[PMID]:28412265
[Au] Autor:De Castro DK; Ng ZY; Holzer PW; Waner M; Cetrulo CL; Fay A
[Ad] Endereço:Private Practitioner, Gordon-Weiss-Schanzlin Vision Institute, San Diego, CA.
[Ti] Título:One-Stage Supramaximal Full-Thickness Wedge Resection of Vascular Lip Anomalies.
[So] Source:J Oral Maxillofac Surg;75(11):2449-2455, 2017 Nov.
[Is] ISSN:1531-5053
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:PURPOSE: Vascular lip anomalies include infantile hemangiomas, venous malformations, and arteriovenous malformations. Surgical management can be complicated by alterations in horizontal length, vertical height, and lip thickness from the underlying pathology. Additional reconstructive challenges include preservation of oral continence, vermillion definition, and the sublabial sulcus. This report describes a technique of supramaximal single-stage full-thickness wedge resection of these lesions. MATERIALS AND METHODS: A retrospective study approved by the institutional review board of patients who underwent full-thickness resection of vascular lip anomalies from December 2007 through February 2013 was performed. Patient demographics, final diagnosis, preoperative treatment, examination findings (pre- and postoperative), intraoperative management, and follow-up findings were reviewed. RESULTS: Eighteen patients (9 female) with a mean age of 25 ± 19.8 years (range, 3 to 70 yr) were identified. Underlying pathologies were arteriovenous malformation (6), port wine stain with secondary soft tissue hypertrophy (6), capillary malformation (1), venous malformation (3), and infantile hemangioma (2). Prior treatments included embolization, lasers, surgical excision, steroids, and propranolol; 8 patients were treatment naive. All patients underwent a single or double pentagonal-shaped wedge resection of the involved upper or lower lip. An average of 3.75 cm (41.7%; range, 20 to 70%) of horizontal lip length was excised. Four patients required additional concomitant debulking of the vermillion. No intraoperative complications were noted. Postoperatively, 1 patient developed wound dehiscence at 12 days and another had a midline depression with mild oral incontinence. Follow-up averaged 1,074 days (range, 371 to 1,777 days) and patients and their parents reported a high degree of satisfaction with the improvement in lip appearance and symmetry except for 1 patient who required further debulking. The sublabial sulcus and vermillion and cutaneous definition were preserved in all cases. CONCLUSION: Despite the traditional recommendation that no more than 30% of lip length be surgically removed, vascular lip anomalies result in tissue hypertrophy, horizontal elongation, ectropion labii, and tissue expansion that allow up to 70% of the lip to be excised.
[Mh] Termos MeSH primário: Malformações Arteriovenosas/cirurgia
Hemangioma/cirurgia
Neoplasias Labiais/cirurgia
Lábio/irrigação sanguínea
Lábio/cirurgia
[Mh] Termos MeSH secundário: Adolescente
Adulto
Idoso
Criança
Pré-Escolar
Feminino
Seres Humanos
Masculino
Meia-Idade
Procedimentos Cirúrgicos Reconstrutivos/métodos
Estudos Retrospectivos
Procedimentos Cirúrgicos Operatórios/métodos
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1711
[Cu] Atualização por classe:171109
[Lr] Data última revisão:
171109
[Sb] Subgrupo de revista:AIM; D; IM
[Da] Data de entrada para processamento:170417
[St] Status:MEDLINE


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[PMID]:28403274
[Au] Autor:Mu EW; Greenbaum SS
[Ti] Título:The Transposition Flap for the Reconstruction of Lower Cutaneous Lip Defects.
[So] Source:J Drugs Dermatol;16(4):385-387, 2017 Apr 01.
[Is] ISSN:1545-9616
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:

The lower cutaneous lip is a highly visible and functionally sensitive unit, and numerous factors must be considered when deciding on the optimal repair for defects in this area. The transposition flap represents an excellent option in the reconstruction of larger lower cutaneous lip defects. We describe the use of random pattern transposition flaps for the repair of lower lateral cutaneous lip defects.

J Drugs Dermatol. 2017;16(4):385-387.

.
[Mh] Termos MeSH primário: Carcinoma Basocelular/cirurgia
Neoplasias Labiais/cirurgia
Lábio/transplante
Cirurgia de Mohs/efeitos adversos
Procedimentos Cirúrgicos Reconstrutivos/métodos
Neoplasias Cutâneas/cirurgia
Retalhos Cirúrgicos/transplante
[Mh] Termos MeSH secundário: Idoso
Idoso de 80 Anos ou mais
Feminino
Seguimentos
Seres Humanos
Masculino
Meia-Idade
Cicatrização
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170914
[Lr] Data última revisão:
170914
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170414
[St] Status:MEDLINE



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