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[PMID]: 29390285 [Au] Autor: Zhang Y; Xin J; Ma Y; Li Q; Liu B [Ad] Endereço: Department of Anesthesiology, West China Hospital of Sichuan University, Chengdu, Sichuan, China. [Ti] Título: Use of Univent tube for intermittent lung isolation during thoracoscopic mediastinal tracheal resection and reconstruction: A case report. [So] Source: Medicine (Baltimore);96(50):e8945, 2017 Dec. [Is] ISSN: 1536-5964 [Cp] País de publicação: United States [La] Idioma: eng [Ab] Resumo: RATIONALE: Primary tracheal adenoid cystic carcinoma of the trachea primary is a rare neoplasm and commonly misdiagnosed. Lung isolation during surgery and ventilation pose a tremendous challenge to anesthesiologists. PATIENT CONCERNS: The authors describe a novel technique of lung isolation and ventilation with a Univent tube during thoracoscopic mediastinal tracheal resection and reconstruction in a female patient. DIAGNOSES: Primary tracheal adenoid cystic carcinoma, nonsmall cell carcinoma. INTERVENTIONS: In this case, tracheal resection and reconstruction were performed. A bronchial blocker of the Univent tube was used as a guide to manipulate the depth of endotracheal tube. OUTCOMES: The intermittent 1-lung ventilation was established successfully. The patient recovered uneventfully and discharged after 10 days. LESSONS: The advantages of approach include a stable airway management without occupying the contracted space of thoracoscope and no potential risk of trapping or barotraumas. [Mh] Termos MeSH primário: Manuseio das Vias Aéreas/métodos Carcinoma Adenoide Cístico/cirurgia Toracoscopia Neoplasias da Traqueia/cirurgia [Mh] Termos MeSH secundário: Carcinoma Adenoide Cístico/diagnóstico Carcinoma Adenoide Cístico/patologia Feminino Seres Humanos Intubação Intratraqueal Meia-Idade Neoplasias da Traqueia/diagnóstico Neoplasias da Traqueia/patologia [Pt] Tipo de publicação: CASE REPORTS; JOURNAL ARTICLE [Em] Mês de entrada: 1802 [Cu] Atualização por classe: 180301 [Lr] Data última revisão: 180301 [Sb] Subgrupo de revista: AIM; IM [Da] Data de entrada para processamento: 180203 [St] Status: MEDLINE [do] DOI: 10.1097/MD.0000000000008945

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[PMID]: 28935346 [Au] Autor: Stamatis G; Fechner S; Rocha M; Weinreich G [Ad] Endereço: Department of Thoracic Surgery and Endoscopy, Ruhrlandklinik, West German Lung Center, University Hospital Essen, University Duisburg-Essen, Essen, Germany. Electronic address: georgios.stamatis@ruhrlandklinik.uk-essen.de. [Ti] Título: Resection of the Tracheobronchial Bifurcation With Complete Preservation of Lung Parenchyma. [So] Source: Ann Thorac Surg;104(5):1741-1747, 2017 Nov. [Is] ISSN: 1552-6259 [Cp] País de publicação: Netherlands [La] Idioma: eng [Ab] Resumo: BACKGROUND: The resection of the tracheobronchial bifurcation with complete preservation of lung parenchyma remains a challenge owing to the limited indications for surgery, anesthesiologic management, operative technique, and postoperative course. The aim of this retrospective study was to evaluate factors influencing the perioperative course and long-term survival. METHODS: Between 1989 and 2014, 19 patients underwent a resection of the distal trachea and carina with complete preservation of lung tissue, 16 for malignant tumors (7 adenoid cystic carcinomas, 3 carcinoid tumors, 3 mucoepidermoid tumors, 2 squamous cell carcinomas, and 1 small cell carcinomas), 2 for inflammatory stenosis, and 1 after a complex traumatic rupture. RESULTS: Surgical approach was posterolateral thoracotomy in 17 patients and median sternotomy in 2. In 16 patients, end-to-end anastomosis was performed, and in 3 patients, combined end-to-end and side-to-end anastomosis were performed. The operative mortality was 0%, the perioperative complication rate was 26.3%. Six patients with adenoid cystic carcinoma and all patients with lung carcinoma received adjuvant radiotherapy; only 1 patient with small cell lung cancer had chemotherapy before surgery. Long-term results are excellent in patients with benign disease, typical and atypical carcinoid tumor, mucoepidermoid carcinoma, and in most patients with adenoid cystic carcinoma. Two patients with lung cancer died 28 and 45 months after surgery, and 1 patient with adenoid cystic carcinoma died 75 months after surgery. CONCLUSIONS: Resection of the tracheobronchial bifurcation with complete preservation of lung indicated for selected patients with local tumor growth at the distal trachea and carina provides low perioperative mortality and complications and results in long-term survival rates. [Mh] Termos MeSH primário: Neoplasias Brônquicas/patologia Neoplasias Brônquicas/cirurgia Tratamentos com Preservação do Órgão/métodos Pneumonectomia/métodos Neoplasias da Traqueia/patologia Neoplasias da Traqueia/cirurgia [Mh] Termos MeSH secundário: Adulto Biópsia por Agulha Neoplasias Brônquicas/diagnóstico por imagem Neoplasias Brônquicas/mortalidade Estudos de Coortes Feminino Seres Humanos Imagem Tridimensional Imuno-Histoquímica Masculino Meia-Idade Tecido Parenquimatoso Prognóstico Estudos Retrospectivos Medição de Risco Taxa de Sobrevida Tomografia Computadorizada por Raios X/métodos Neoplasias da Traqueia/diagnóstico por imagem Neoplasias da Traqueia/mortalidade Resultado do Tratamento Adulto Jovem [Pt] Tipo de publicação: JOURNAL ARTICLE [Em] Mês de entrada: 1711 [Cu] Atualização por classe: 171109 [Lr] Data última revisão: 171109 [Sb] Subgrupo de revista: AIM; IM [Da] Data de entrada para processamento: 170923 [St] Status: MEDLINE

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[PMID]: 28816991 [Au] Autor: Li X; Li J; Rao X; Ao Q; Cao X; Huang Y; Zhang S; Fang X; Liu X; Xie M [Ad] Endereço: aDepartment of Pulmonary and Critical Care Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan bKey Laboratory of Respiratory Diseases, National Ministry of Health of the People's Republic of China and National Clinical Research Center for Respiratory Disease cDepartment of Dermatology, Zhengzhou Maternal and Child Health Hospital, Zhengzhou dDepartment of Pathology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China. [Ti] Título: A case report of tracheal inflammatory myofibroblastic tumor in a 34-week pregnant woman misdiagnosed with asthma. [So] Source: Medicine (Baltimore);96(33):e7872, 2017 Aug. [Is] ISSN: 1536-5964 [Cp] País de publicação: United States [La] Idioma: eng [Ab] Resumo: RATIONALE: Inflammatory myofibroblastic tumor (IMT) is an uncommon neoplastic entity with a tendency of local recurrence and a low risk of distant metastasis. Involvement of trachea is extremely rare. PATIENT CONCERNS: A 34-week pregnant woman previously diagnosed with asthma for 2 months was admitted with persistent wheezing and hemoptysis. A computed tomography scan and bronchoscopy revealed a gigantic polyp in the trachea. DIAGNOSES: Tracheal inflammatory myofibroblastic tumor. INTERVENTIONS: The mass was removed with an electrocautery snare and identified histologically as an IMT. Further immunochemical staining showed strong positive staining for smooth muscle actin and platelet-derived growth factor receptor α (PDGFRA), weak positive staining for caldesmon, and negative staining for anaplastic lymphoma kinase (ALK)1, desmin, S-100, and CD34. The tracheal IMT strongly expressed estrogen receptor-α (ER-α), which indicated that the development of this rare IMT might have been associated with hormone fluctuations that occurred during the pregnancy. OUTCOMES: Follow-up and histological analyses revealed no evidence of recurrence and metastasis. LESSONS: This report describes an extremely rare case of a tracheal IMT that presented a diagnostic dilemma for the clinician and the pathologist. Tracheal IMT is a challenge for the clinician in diagnosis due to the nonspecific clinical presentation. Histology and immunohistochemistry are required to reach an accurate diagnosis of IMT. [Mh] Termos MeSH primário: Asma/diagnóstico Complicações Neoplásicas na Gravidez/diagnóstico Neoplasias de Tecidos Moles/diagnóstico Neoplasias da Traqueia/diagnóstico [Mh] Termos MeSH secundário: Adulto Erros de Diagnóstico Feminino Seres Humanos Gravidez Complicações Neoplásicas na Gravidez/cirurgia Neoplasias de Tecidos Moles/cirurgia Neoplasias da Traqueia/cirurgia [Pt] Tipo de publicação: CASE REPORTS; JOURNAL ARTICLE [Em] Mês de entrada: 1709 [Cu] Atualização por classe: 170911 [Lr] Data última revisão: 170911 [Sb] Subgrupo de revista: AIM; IM [Da] Data de entrada para processamento: 170818 [St] Status: MEDLINE [do] DOI: 10.1097/MD.0000000000007872

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[PMID]: 28767607 [Au] Autor: Li M; Zhu W; Khan RSU; Saeed U; Shi S; Luo Z [Ad] Endereço: aDepartment of Respiratory Medicine bDepartment of Pharmacy, First Affiliated Hospital of Kunming Medical University cPostgraduate School of Kunming Medical University, Kunming, Yunnan, P.R. China. [Ti] Título: Primary clear cell carcinoma of the trachea: A CARE-compliant case report. [So] Source: Medicine (Baltimore);96(31):e7709, 2017 Aug. [Is] ISSN: 1536-5964 [Cp] País de publicação: United States [La] Idioma: eng [Ab] Resumo: RATIONALE: Primary clear cell carcinoma of the lung is a rare condition, and presentation as an endotracheal lesion is even more unusual. In this report, we present a patient with clear cell carcinoma occurring in the trachea, which obstructed the tracheal lumen and lead to the respiratory distress. PATIENT CONCERNS: A 60-year old female patient was admitted due to a 6-month history of dyspnea with worsening symptoms for 1 month. Chest CT scan revealed a smooth nodular shadow with homogeneous density on the wall of upper trachea. DIAGNOSIS: Bronchoscopy therapy and surgical removal of the tumor were performed. The histopathological diagnosis revealed clear cell carcinoma. INTERVENTION: Surgical removal of the clear cell carcinoma was performed. OUTCOMES: The patient recovered well after the surgery and is now being followed-up after hospital discharge. LESSONS: Bronchoscopy is an essential tool for diagnosis of tracheal clear cell carcinoma. Surgical removal should be performed if possible. [Mh] Termos MeSH primário: Adenocarcinoma de Células Claras/diagnóstico Adenocarcinoma de Células Claras/cirurgia Neoplasias da Traqueia/diagnóstico Neoplasias da Traqueia/cirurgia [Mh] Termos MeSH secundário: Adenocarcinoma de Células Claras/complicações Adenocarcinoma de Células Claras/patologia Diagnóstico Diferencial Dispneia/diagnóstico Dispneia/etiologia Dispneia/patologia Dispneia/cirurgia Feminino Seres Humanos Meia-Idade Traqueia/diagnóstico por imagem Traqueia/patologia Traqueia/cirurgia Neoplasias da Traqueia/complicações Neoplasias da Traqueia/patologia [Pt] Tipo de publicação: CASE REPORTS; JOURNAL ARTICLE [Em] Mês de entrada: 1708 [Cu] Atualização por classe: 171013 [Lr] Data última revisão: 171013 [Sb] Subgrupo de revista: AIM; IM [Da] Data de entrada para processamento: 170803 [St] Status: MEDLINE [do] DOI: 10.1097/MD.0000000000007709

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[PMID]: 28734442 [Au] Autor: Huang J; Qiu Y; Chen L; Liu H; Dong Q; Liang L; He J; He J; Chen H [Ad] Endereço: Department of Thoracic Surgery, The First Affiliated Hospital of Guangzhou Medical University, Guangdong, China; Guangzhou Research Institute of Respiratory Disease, China Key Laboratory of Respiratory Disease, Guangdong, China; National Center for Clinical Trials on Respiratory Diseases, Guangdong, [Ti] Título: Nonintubated Spontaneous Respiration Anesthesia for Tracheal Glomus Tumor. [So] Source: Ann Thorac Surg;104(2):e161-e163, 2017 Aug. [Is] ISSN: 1552-6259 [Cp] País de publicação: Netherlands [La] Idioma: eng [Ab] Resumo: Previous tracheal surgeries were performed under tracheal and cross-field intubation. However, the intubation would lead to bleeding if the tumors were large or hemorrhagic. Moreover, the tracheal intubation might interfere the surgical vision and anastomosis during the reconstruction process. Therefore, we performed a tracheal tumor resection and reconstruction via nonintubated spontaneous anesthesia. We describe the feasibility and safety of tracheal surgeries via such anesthesia. [Mh] Termos MeSH primário: Tumor Glômico/cirurgia Procedimentos Cirúrgicos Reconstrutivos/métodos Cirurgia Torácica Vídeoassistida/métodos Traqueia/cirurgia Neoplasias da Traqueia/cirurgia Traqueotomia/métodos [Mh] Termos MeSH secundário: Adulto Anestesia/métodos Broncoscopia Tumor Glômico/diagnóstico Seres Humanos Intubação Intratraqueal Masculino Tomografia Computadorizada por Raios X Neoplasias da Traqueia/diagnóstico [Pt] Tipo de publicação: CASE REPORTS; JOURNAL ARTICLE; VIDEO-AUDIO MEDIA [Em] Mês de entrada: 1709 [Cu] Atualização por classe: 170906 [Lr] Data última revisão: 170906 [Sb] Subgrupo de revista: AIM; IM [Da] Data de entrada para processamento: 170724 [St] Status: MEDLINE

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[PMID]: 28592026 [Au] Autor: Ding YF; Chen L; Huang HD; Dong YC; Yao XP; Huang Y; Wang Q; Zhang W; Li Q; Bai C [Ad] Endereço: Department of Respiratory and Critical Care Medicine, Changhai Hospital Affiliated to the Second Military Medical University, Shanghai 200433, China. [Ti] Título: [Clinical analysis of therapeutic bronchoscopy for tracheal neoplasm]. [So] Source: Zhonghua Jie He He Hu Xi Za Zhi;40(6):435-439, 2017 Jun 12. [Is] ISSN: 1001-0939 [Cp] País de publicação: China [La] Idioma: chi [Ab] Resumo: To analyze the clinical features in adults with tracheal neoplasm and to evaluate the efficacy of interventional bronchoscopic treatment. We retrospectively analyzed the clinical features of 43 adults undergoing therapeutic bronchoscopy for tracheal neoplasm diagnosed in Changhai Hospital affiliated to the Second Military Medical University from January 2004 to July 2014.The degree of stenosis, the grade of dyspnea, and Karnofsky performance status scale were evaluated before and after the last procedure. All cases were followed up for 2 years. The 43 cases took (4.6±3.9) months on average to be diagnosed since initial symptom. The initial misdiagnosis rate was 41.9%(18/43), and 11 cases were mistaken for asthma (11/43). Malignant tumors were more common than benign tumors for tracheal neoplasm in adults. Squamous cell carcinoma and adenoid cystic carcinoma were the top 2 histological types. Central airway obstruction was completely or partially alleviated with significant relief of dyspnea after the procedures, and all 6 cases of tracheal benign tumors got complete alleviation (the overall response rate was 100%). The grade of dyspnea was 3.2±0.7 before and 1.5±0.8 after the procedures( =6.63, <0.05). The value of KPS was 63±12 before and 83±11 after the procedures( =5.78, <0.05). The 2-year survival rate of 6 cases of tracheal benign tumors was 100.0%, and 1 case of papillomatosis had a relapse. The 1-year survival rate and 2-year survival rate of 37 cases of tracheal malignant tumors were 59.5% and 43.2% respectively with a median survival of 13.6 months. Therapeutic bronchoscopic interventions provide significantly alleviation of central airway obstruction and result in improvement in shortness of breath and quality of life for tracheal neoplasm. [Mh] Termos MeSH primário: Obstrução das Vias Respiratórias/etiologia Broncoscopia/métodos Carcinoma de Células Escamosas/cirurgia Neoplasias da Traqueia/cirurgia [Mh] Termos MeSH secundário: Adulto Idoso Obstrução das Vias Respiratórias/cirurgia Carcinoma de Células Escamosas/diagnóstico Carcinoma de Células Escamosas/mortalidade Constrição Patológica Dispneia/etiologia Feminino Seres Humanos Masculino Meia-Idade Recidiva Local de Neoplasia Qualidade de Vida Estudos Retrospectivos Taxa de Sobrevida Neoplasias da Traqueia/diagnóstico Neoplasias da Traqueia/mortalidade Resultado do Tratamento [Pt] Tipo de publicação: EVALUATION STUDIES; JOURNAL ARTICLE [Em] Mês de entrada: 1709 [Cu] Atualização por classe: 170912 [Lr] Data última revisão: 170912 [Sb] Subgrupo de revista: IM [Da] Data de entrada para processamento: 170609 [St] Status: MEDLINE [do] DOI: 10.3760/cma.j.issn.1001-0939.2017.06.008

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[PMID]: 28542046 [Au] Autor: Dunkman WJ; Nicoara A; Schroder J; Wahidi MM; El Manafi A; Bonadonna D; Giovacchini CX; Lombard FW [Ad] Endereço: From the *Department of Anesthesiology, †Department of Surgery, ‡Department of Internal Medicine, and ∥Perfusion Services, Duke University Medical Center, Durham, North Carolina; §Staten Island University Hospital / Northwell Health, Staten Island, New York; and ¶Vanderbilt University Medical Center, Nashville, Tennessee. [Ti] Título: Elective Venovenous Extracorporeal Membrane Oxygenation for Resection of Endotracheal Tumor: A Case Report. [So] Source: A A Case Rep;9(4):97-100, 2017 Aug 15. [Is] ISSN: 2325-7237 [Cp] País de publicação: United States [La] Idioma: eng [Ab] Resumo: We present a case in which we electively used venovenous extracorporeal membrane oxygenation (VV-ECMO) to facilitate safe resection of a nearly obstructing airway tumor near the carina in a 37-year-old male. The patient was brought to the operating room and underwent bifemoral cannulation for VV-ECMO under light sedation while maintaining spontaneous ventilation. After VV-ECMO was initiated, general anesthesia was induced, and the tumor was resected via rigid bronchoscopy. After resection, the patient was intubated, weaned from ECMO, decannulated, awoken, extubated, and taken to the postanesthesia care unit for recovery. [Mh] Termos MeSH primário: Oxigenação por Membrana Extracorpórea Neurilemoma/cirurgia Neoplasias da Traqueia/cirurgia [Mh] Termos MeSH secundário: Adulto Broncoscopia/métodos Oxigenação por Membrana Extracorpórea/métodos Seres Humanos Masculino Traqueia/cirurgia [Pt] Tipo de publicação: CASE REPORTS; JOURNAL ARTICLE [Em] Mês de entrada: 1710 [Cu] Atualização por classe: 171010 [Lr] Data última revisão: 171010 [Sb] Subgrupo de revista: IM [Da] Data de entrada para processamento: 170526 [St] Status: MEDLINE [do] DOI: 10.1213/XAA.0000000000000537

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[PMID]: 28502275 [Au] Autor: Hui A; Hong P; Bezuhly M [Ad] Endereço: Faculty of Medicine,Dalhousie University,Halifax,Nova Scotia,Canada. [Ti] Título: Use of acellular dermal matrices in laryngotracheal and pharyngeal reconstruction: systematic review. [So] Source: J Laryngol Otol;131(7):585-592, 2017 Jul. [Is] ISSN: 1748-5460 [Cp] País de publicação: England [La] Idioma: eng [Ab] Resumo: BACKGROUND: Acellular dermal matrices are increasingly used in laryngotracheal and pharyngeal reconstruction, but specific indications and the type of acellular dermal matrix used vary. The authors systematically reviewed outcomes relating to acellular dermal matrix use in head and neck reconstruction. METHODS: Electronic databases were searched through 1 May 2016 for literature on acellular dermal matrix use in laryngotracheal and pharyngeal reconstruction. Studies were appraised for surgical indications, outcomes and study design. RESULTS: Eleven publications with 170 cases were included. Eight articles reported on acellular dermal matrix use in oncological reconstruction. Most studies were case series; no high-level evidence studies were identified. Graft extrusion was more common in non-oncological applications. In general, post-oncological reconstruction with an acellular dermal matrix demonstrated complication rates similar to those reported without an acellular dermal matrix. CONCLUSION: Evidence in support of acellular dermal matrix use in head and neck reconstruction is generally poor. Prospective comparative studies are required to define the indications, safety and effectiveness of acellular dermal matrices in laryngotracheal and pharyngeal reconstruction. [Mh] Termos MeSH primário: Derme Acelular Carcinoma de Células Escamosas/cirurgia Cervicoplastia/métodos Neoplasias Otorrinolaringológicas/cirurgia [Mh] Termos MeSH secundário: Carcinoma de Células Escamosas/patologia Seguimentos Neoplasias Laríngeas/cirurgia Estadiamento de Neoplasias Neoplasias Otorrinolaringológicas/patologia Neoplasias Faríngeas/cirurgia Retalhos Cirúrgicos/cirurgia Neoplasias da Traqueia/cirurgia Resultado do Tratamento [Pt] Tipo de publicação: JOURNAL ARTICLE; REVIEW [Em] Mês de entrada: 1708 [Cu] Atualização por classe: 170817 [Lr] Data última revisão: 170817 [Sb] Subgrupo de revista: AIM; IM [Da] Data de entrada para processamento: 170516 [St] Status: MEDLINE [do] DOI: 10.1017/S0022215117001049

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[PMID]: 28407313 [Au] Autor: He J; Shen J; Huang J; Dai C; Liang W; Ye M; Kong M; Chen B; Zhu C; He J [Ad] Endereço: Department of Thoracic Surgery, the First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China. [Ti] Título: Prognosis of primary tracheal tumor: A population-based analysis. [So] Source: J Surg Oncol;115(8):1004-1010, 2017 Jun. [Is] ISSN: 1096-9098 [Cp] País de publicação: United States [La] Idioma: eng [Ab] Resumo: BACKGROUND: To elucidate the survival outcomes of tracheal tumors and to propose the potential stage of tracheal tumors. METHOD: All cases of primary tracheal malignant tumors were extracted from the Surveillance, Epidemiology, and End Results database (SEER) during 1973-2013. The overall survival was calculated using Kaplan-Meier method. Cox regression was utilized to identify the prognostic factors. RESULT: A total of 287 cases were finally included. The median age of the patients was 59 years. Male patients accounted for 56.1%. The median survival was 57 months. Patients were categorized as Extension1 to 4 (E1-4) and N0-N3. E1 group with size <4 cm had the best prognosis. While E1 >4 cm, E2 and E3 <3 cm groups had similar outcomes, which were superior to E3 >3 cm group. E4 was the worst. N0 patients had ideal prognosis, which were better than N1 and N2 patients. The 3-year survival rates of each T category were 74.7%, 57.3%, 28.1%, and 9.1%, respectively. In multivariate analysis, age, histology, tumor size, and extension were independent prognostic factors. CONCLUSION: Patients with old age, large tumor size, advanced extension or no surgery may have worse prognosis. The proposed T category of tracheal tumor incorporating tumor extension and size helped to predict survival outcomes. [Mh] Termos MeSH primário: Neoplasias da Traqueia/diagnóstico Neoplasias da Traqueia/mortalidade [Mh] Termos MeSH secundário: Adolescente Adulto Fatores Etários Idoso Idoso de 80 Anos ou mais Criança Pré-Escolar Feminino Seres Humanos Estimativa de Kaplan-Meier Masculino Meia-Idade Estadiamento de Neoplasias Prognóstico Modelos de Riscos Proporcionais Estudos Retrospectivos Fatores de Risco Programa de SEER Taxa de Sobrevida Neoplasias da Traqueia/patologia Carga Tumoral Estados Unidos/epidemiologia Adulto Jovem [Pt] Tipo de publicação: JOURNAL ARTICLE [Em] Mês de entrada: 1709 [Cu] Atualização por classe: 170906 [Lr] Data última revisão: 170906 [Sb] Subgrupo de revista: IM [Da] Data de entrada para processamento: 170414 [St] Status: MEDLINE [do] DOI: 10.1002/jso.24611

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[PMID]: 28255381 [Au] Autor: Serbanescu GL; Anghel RM [Ad] Endereço: Prof. Dr. Al. Trestioreanu" Institute of Oncology, Bucharest, Romania. [Ti] Título: Can endobronchial or endotracheal metastases appear from rectal adenocarcinoma? [So] Source: J Med Life;10(1):66-69, 2017 Jan-Mar. [Is] ISSN: 1844-3117 [Cp] País de publicação: Romania [La] Idioma: eng [Ab] Resumo: Endobronchial and endotracheal metastases from extra-pulmonary solid tumors are rare. We reported the case of a patient diagnosed with endobronchial and endotracheal metastases from rectal adenocarcinoma. Patient P.G., 62 years old, was diagnosed with a rectal tumor in 2011, for which, a surgical intervention was performed (pT3 pN2a M0, stage IIIB). Afterwards, she underwent adjuvant chemotherapy and concomitant radiochemotherapy. In September 2013, the chest CT showed 2 nodules for which, an incomplete surgical resection was done and which were histopathologically diagnosed as metastases from rectal cancer. The patient continued the treatment with chemotherapy associated with Bevacizumab and after 6 months only Bevacizumab for maintenance. In June 2015, the chest CT pointed out a nodule in the right upper lobe and the bronchoscopy highlighted a 4-5 mm lesion at the level of the right primary bronchus, whose biopsy proved the rectal origin. Afterwards, another surgical intervention was performed. Unfortunately, the postoperative chest CT revealed an intratracheal tissue mass (11/ 7mm) and multiple metastases in the right lung. The bronchoscopy showed 2 endotracheal lesions, out of which one was biopsied (histopathological result of metastasis from rectal cancer). Despite the fact that chemotherapy was continued, other endobronchial lesions appeared. All of them were removed and the patient started radiotherapy on the tracheal area. Afterwards, she refused to continue chemotherapy. The last bronchoscopy highlighted one endobronchial and two endotracheal secondary malignant lesions. Endobronchial and endotracheal metastases must be taken into consideration in all the patients with a history of extra-pulmonary cancer. CT = computed tomography, MRI = magnetic resonance imaging, IMRT = intensity-modulated radiotherapy, ESMO = European Society for Medical Oncology, NCCN = National Comprehensive Cancer Network, iv = intravenous, PET - CT = Positron Emission Tomography - Computed Tomography. [Mh] Termos MeSH primário: Neoplasias Brônquicas/secundário Neoplasias Retais/patologia Neoplasias da Traqueia/secundário [Mh] Termos MeSH secundário: Adenocarcinoma/diagnóstico por imagem Adenocarcinoma/patologia Adenocarcinoma/radioterapia Adenocarcinoma/cirurgia Neoplasias Brônquicas/cirurgia Broncoscopia Feminino Seres Humanos Meia-Idade Neoplasias Retais/diagnóstico por imagem Neoplasias Retais/radioterapia Neoplasias Retais/cirurgia Tomografia Computadorizada por Raios X Neoplasias da Traqueia/cirurgia [Pt] Tipo de publicação: CASE REPORTS; JOURNAL ARTICLE [Em] Mês de entrada: 1705 [Cu] Atualização por classe: 170501 [Lr] Data última revisão: 170501 [Sb] Subgrupo de revista: IM [Da] Data de entrada para processamento: 170304 [St] Status: MEDLINE

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