Base de dados : MEDLINE
Pesquisa : C04.588.614.250.195.885.500 [Categoria DeCS]
Referências encontradas : 659 [refinar]
Mostrando: 1 .. 10   no formato [Detalhado]

página 1 de 66 ir para página                         

  1 / 659 MEDLINE  
              next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:29020588
[Au] Autor:Curran MA; Madhavan VL; Caruso PA; Ebb DH; Williams EA
[Ad] Endereço:From the Departments of Pediatrics (M.A.C., V.L.M., D.H.E.), Radiology (P.A.C.), and Pathology (E.A.W.), Massachusetts General Hospital, and the Departments of Pediatrics (M.A.C., V.L.M., D.H.E.), Radiology (P.A.C.), and Pathology (E.A.W.), Harvard Medical School - both in Boston.
[Ti] Título:Case 31-2017. A 19-Month-Old Girl with Failure to Thrive.
[So] Source:N Engl J Med;377(15):1468-1477, 2017 10 12.
[Is] ISSN:1533-4406
[Cp] País de publicação:United States
[La] Idioma:eng
[Mh] Termos MeSH primário: Astrocitoma/diagnóstico por imagem
Insuficiência de Crescimento/etiologia
Neoplasias Hipotalâmicas/diagnóstico por imagem
[Mh] Termos MeSH secundário: Astrocitoma/complicações
Astrocitoma/patologia
Análise Química do Sangue
Caquexia/etiologia
Diagnóstico Diferencial
Ingestão de Energia
Feminino
Seres Humanos
Doenças Hipotalâmicas/diagnóstico
Neoplasias Hipotalâmicas/complicações
Neoplasias Hipotalâmicas/patologia
Lactente
Imagem por Ressonância Magnética
[Pt] Tipo de publicação:CASE REPORTS; CLINICAL CONFERENCE; JOURNAL ARTICLE
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171019
[Lr] Data última revisão:
171019
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:171012
[St] Status:MEDLINE
[do] DOI:10.1056/NEJMcpc1706106


  2 / 659 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:28259055
[Au] Autor:Özyurt J; Müller HL; Warmuth-Metz M; Thiel CM
[Ad] Endereço:Biological Psychology Lab, Department of Psychology, Faculty of Medicine and Health Sciences, Carl von Ossietzky Universität Oldenburg, Oldenburg, Germany. Electronic address: jale.oezyurt@uni-oldenburg.de.
[Ti] Título:Hypothalamic tumors impact gray and white matter volumes in fronto-limbic brain areas.
[So] Source:Cortex;89:98-110, 2017 Apr.
[Is] ISSN:1973-8102
[Cp] País de publicação:Italy
[La] Idioma:eng
[Ab] Resumo:Patients with hypothalamic involvement of a sellar/parasellar tumor often suffer from cognitive and social-emotional deficits that a lesion in the hypothalamus cannot fully explain. It is conceivable that these deficits are partly due to distal changes in hypothalamic networks, evolving secondary to a focal lesion. Focusing on childhood-onset craniopharyngioma patients, we aimed at investigating the impact of hypothalamic lesions on gray and white matter areas densely connected to the hypothalamus, and to relate structural changes to neuropsychological deficits frequently observed in patients. We performed a voxel-based morphometric analysis based on data of 11 childhood-onset craniopharyngioma patients with hypothalamic tumor involvement, and 18 healthy controls (median age: 17.2 and 17.4 yrs.). Whole-brain analyses were used to test for volumetric differences between the groups (T-tests) and subsequent regression analyses were used to correlate neuropsychological performance with gray and white matter volumes within the patient group. Patients compared to controls had significantly reduced gray matter volumes in areas of the anterior and posterior limbic subsystems which are densely connected with the hypothalamus. In addition, a reduction in white matter volumes was observed in tracts connecting the hypothalamus to other limbic areas. Worse long-term memory retrieval was correlated with smaller gray matter volumes in the posterior cingulate cortex. Our data provide the first evidence that hypothalamic tumor involvement impacts gray and white matter volumes in limbic areas, outside the area of tumor growth. Notably, the functional range of the two limbic subsystems affected, strikingly parallels the two major domains of psychological complaints in patients i.e., deficits in episodic memory and in socio-emotional functioning. We suggest that focal hypothalamic lesions may trigger distal changes in connected brain areas, which then contribute to the impairments in cognitive, social and emotional performance often observable in patients, and not explicable by a hypothalamic lesion alone.
[Mh] Termos MeSH primário: Craniofaringioma/diagnóstico por imagem
Lobo Frontal/diagnóstico por imagem
Substância Cinzenta/diagnóstico por imagem
Neoplasias Hipotalâmicas/diagnóstico por imagem
Sistema Límbico/diagnóstico por imagem
Substância Branca/diagnóstico por imagem
[Mh] Termos MeSH secundário: Adolescente
Adulto
Criança
Craniofaringioma/patologia
Feminino
Lobo Frontal/patologia
Substância Cinzenta/patologia
Seres Humanos
Neoplasias Hipotalâmicas/patologia
Sistema Límbico/patologia
Masculino
Tamanho do Órgão
Substância Branca/patologia
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171009
[Lr] Data última revisão:
171009
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170305
[St] Status:MEDLINE


  3 / 659 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:28009226
[Au] Autor:Miller C; Guillaume D; Dusenbery K; Clark HB; Moertel C
[Ad] Endereço:Departments of 1 Neurosurgery.
[Ti] Título:Report of effective trametinib therapy in 2 children with progressive hypothalamic optic pathway pilocytic astrocytoma: documentation of volumetric response.
[So] Source:J Neurosurg Pediatr;19(3):319-324, 2017 Mar.
[Is] ISSN:1933-0715
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Brain tumors are the most common solid tumor in childhood, and astrocytomas account for the largest proportion of these tumors. Increasing sophistication in genetic testing has allowed for the detection of specific mutations within tumor subtypes that may represent targets for individualized tumor treatment. The mitogen-activating protein kinase (MAPK) pathway and, more specifically, BRAF mutations have been shown to be prevalent in pediatric pilocytic astrocytomas and may represent one such area to target. Herein, the authors describe 2 cases of inoperable, chemotherapy-resistant pediatric pilocytic astrocytomas with a documented response to trametinib, an MAPK pathway inhibitor. While these cases were not treated in the setting of a clinical trial, their data support further ongoing clinical trial investigation to evaluate the safety and efficacy of this agent in pediatric low-grade gliomas.
[Mh] Termos MeSH primário: Antineoplásicos/uso terapêutico
Astrocitoma/diagnóstico por imagem
Progressão da Doença
Neoplasias Hipotalâmicas/diagnóstico por imagem
Neoplasias do Nervo Óptico/diagnóstico por imagem
Piridonas/uso terapêutico
Pirimidinonas/uso terapêutico
[Mh] Termos MeSH secundário: Astrocitoma/tratamento farmacológico
Pré-Escolar
Feminino
Seres Humanos
Neoplasias Hipotalâmicas/tratamento farmacológico
Lactente
Neoplasias do Nervo Óptico/tratamento farmacológico
Tamanho do Órgão
Resultado do Tratamento
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Antineoplastic Agents); 0 (Pyridones); 0 (Pyrimidinones); 33E86K87QN (trametinib)
[Em] Mês de entrada:1703
[Cu] Atualização por classe:170316
[Lr] Data última revisão:
170316
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161224
[St] Status:MEDLINE
[do] DOI:10.3171/2016.9.PEDS16328


  4 / 659 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:27544339
[Au] Autor:Zoli M; Marucci G; Milanese L; Bonfatti R; Sturiale C; Ernesto P; Frank G; Mazzatenta D
[Ad] Endereço:Center of Surgery for Pituitary Tumors and Endoscopic Skull Base Surgery, Department of Neurosurgery, IRCCS Istituto delle Scienze Neurologiche, Bologna, Italy. Electronic address: matteo.zoli4@unibo.it.
[Ti] Título:Suction Filter in Endoscopic Endonasal Surgery: A Technical Note.
[So] Source:World Neurosurg;95:464-468, 2016 Nov.
[Is] ISSN:1878-8769
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: The collection of the greatest possible amount of pathologic tissue is of paramount importance in neurosurgery to achieve the most accurate histopathologic diagnosis, to perform all of the necessary biomolecular tests on the pathologic specimen, and to collect biological material for basic or translational science studies. This problem is particularly relevant in pituitary surgery because of the possible small size and soft consistency of tumors, which make them suitable for removal through suction, reducing the amount of available pathologic tissue. To solve this issue, we adopted a filter connected to the suction tube, which allows the surgeon to collect all of the tissue aspirated during surgery. METHODS: Our experience of 1734 endoscopic endonasal procedures, performed adopting this device since 1998 to December 2015, has been revised to assess its advantages and limitations. RESULTS: This system is easy-to-use, does not impair the surgical maneuvers, and does not add any relevant cost to the surgery. The tissue collected through the filter proved useful for diagnostic histologic and biomolecular analyses and for research purposes, without any relevant artifacts as a result of this method of collection. CONCLUSIONS: The use of a filter has allowed us to obtain the greatest amount possible of pathologic tissue at each surgery. This surgical material has revealed to be helpful both for diagnostic and basic science purposes. The use of the filter has proven to be of particular importance for microadenomas, soft tumors, and supradiaphragmatic or skull base lesions with heterogeneous features, improving the accuracy of histopathologic diagnosis.
[Mh] Termos MeSH primário: Neoplasias do Sistema Nervoso Central/cirurgia
Neuroendoscopia/instrumentação
Sucção/instrumentação
[Mh] Termos MeSH secundário: Adenoma/cirurgia
Cistos do Sistema Nervoso Central/cirurgia
Condrossarcoma/cirurgia
Cordoma/cirurgia
Fossa Craniana Posterior/cirurgia
Craniofaringioma/cirurgia
Glioma/cirurgia
Seres Humanos
Neoplasias Hipotalâmicas/cirurgia
Neoplasias Meníngeas/cirurgia
Meningioma/cirurgia
Cirurgia Endoscópica por Orifício Natural
Neuroendoscopia/métodos
Nariz
Neoplasias Hipofisárias/cirurgia
Plasmocitoma/cirurgia
Estudos Retrospectivos
Neoplasias da Base do Crânio/cirurgia
Sucção/métodos
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171002
[Lr] Data última revisão:
171002
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160822
[St] Status:MEDLINE


  5 / 659 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:27450285
[Au] Autor:Wang Z; Yan HM; Zhou XR; Liu JK; Chang JY; Wang YT
[Ad] Endereço:Department of Neurosurgery, Wei Fang People's Hospital, 151 Guangwen Street, Weifang 261041, China.
[Ti] Título:Spontaneous intratumoural and intraventricular haemorrhage associated with a pilomyxoid astrocytoma in the hypothalamic/chiasmatic region.
[So] Source:J Clin Neurosci;33:217-220, 2016 Nov.
[Is] ISSN:1532-2653
[Cp] País de publicação:Scotland
[La] Idioma:eng
[Ab] Resumo:Pilomyxoid astrocytoma (PMA) is a rare, low-grade glioma that is recognised as a variant of pilocytic astrocytoma. There have been few reports on this pathologic entity presenting with spontaneous haemorrhage. In this study, we report a rare case of PMA in the hypothalamic/chiasmatic region presenting with intratumoural and intraventricular haemorrhage. An external ventricular drain was urgently inserted. A ventriculo-peritoneal shunt (VP) was undergone 4weeks thereafter. The patient received fractionated Gamma Knife radiosurgery in another hospital 3weeks after the VP shunt. Three months later, subtotal resection of the tumour was performed in our hospital via a pterional approach. The pathological diagnosis was PMA. Postoperatively, no adjuvant therapy was given, and the neurologic deficits were improved. However, the presentation of endocrine deficits remained. Notably, PMAs in the hypothalamic/chiasmatic region presenting with massive intratumoural and intraventricular haemorrhage may result in a severe condition and long-term impairment of endocrine function. Long-term follow-up is required to monitor the recurrence of the tumour and endocrinopathy.
[Mh] Termos MeSH primário: Astrocitoma/complicações
Ventrículos Cerebrais/patologia
Neoplasias Hipotalâmicas/complicações
Hemorragias Intracranianas/etiologia
[Mh] Termos MeSH secundário: Adolescente
Astrocitoma/diagnóstico por imagem
Astrocitoma/cirurgia
Ventrículos Cerebrais/diagnóstico por imagem
Ventrículos Cerebrais/cirurgia
Drenagem
Seres Humanos
Neoplasias Hipotalâmicas/diagnóstico por imagem
Neoplasias Hipotalâmicas/cirurgia
Hemorragias Intracranianas/diagnóstico por imagem
Hemorragias Intracranianas/cirurgia
Imagem por Ressonância Magnética
Masculino
Radiocirurgia
Tomografia Computadorizada por Raios X
Resultado do Tratamento
Derivação Ventriculoperitoneal
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Em] Mês de entrada:1702
[Cu] Atualização por classe:170202
[Lr] Data última revisão:
170202
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160725
[St] Status:MEDLINE


  6 / 659 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
[PMID]:27258590
[Au] Autor:Emelifeonwu JA; Sokol D; Gallo P; Kandasamy J; Kaliaperumal C
[Ad] Endereço:Department of Paediatric Neurosurgery, Royal Hospital for Sick Children, Edinburgh, United Kingdom.
[Ti] Título:Long-tunnelled external ventricular drain as a long-term treatment option for hydrocephalus in a child with an unresectable low-grade supratentorial tumor: case report.
[So] Source:J Neurosurg Pediatr;18(4):430-433, 2016 Oct.
[Is] ISSN:1933-0715
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:The authors report a case of a child with hypothalamic-origin pilocytic astrocytoma and hydrocephalus, which was refractory to treatment with a ventriculoperitoneal shunt due to high CSF protein content. With parental education, the child's hydrocephalus was managed long-term in the community with a long-tunnelled external ventricular drain, which was maintained by his parents. To the authors' knowledge this is the first report of this management option as a long-term measure. No harm has come to the patient. The authors propose long-term, long-tunnelled external ventricular drain as a viable treatment option for such patients.
[Mh] Termos MeSH primário: Astrocitoma/complicações
Derivações do Líquido Cefalorraquidiano/métodos
Hidrocefalia/complicações
Hidrocefalia/cirurgia
Neoplasias Hipotalâmicas/complicações
Cuidados Paliativos/métodos
[Mh] Termos MeSH secundário: Astrocitoma/diagnóstico por imagem
Astrocitoma/tratamento farmacológico
Astrocitoma/patologia
Seres Humanos
Hidrocefalia/diagnóstico por imagem
Neoplasias Hipotalâmicas/diagnóstico por imagem
Neoplasias Hipotalâmicas/tratamento farmacológico
Neoplasias Hipotalâmicas/patologia
Lactente
Masculino
Gradação de Tumores
Reoperação
Fatores de Tempo
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Em] Mês de entrada:1702
[Cu] Atualização por classe:170817
[Lr] Data última revisão:
170817
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160604
[St] Status:MEDLINE


  7 / 659 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:27004758
[Au] Autor:Abou Al-Shaar H; Raheja A; Palmer CA; Schmidt MH; Couldwell WT
[Ad] Endereço:College of Medicine, Alfaisal University, Riyadh, Saudi Arabia.
[Ti] Título:Hypothalamic-Optochiasmatic Pilocytic Astrocytoma Associated with Occipital and Sacral Spinal Cavernomas: A Mere Coincidence or a True Association?
[So] Source:World Neurosurg;90:707.e17-707.e21, 2016 Jun.
[Is] ISSN:1878-8769
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: The co-occurrence of cerebral gliomas and cavernous angiomas is rarely encountered in clinical practice. All reported cases with such association have occurred within the brain with none involving the spinal cord. CASE DESCRIPTION: The authors report the case of a hypothalamic-optochiasmatic pilocytic astrocytoma coexisting with right occipital and sacral spinal cavernomas. This 30-year-old man had an 8-year history of chronic lower back pain. Spinal magnetic resonance imaging (MRI) demonstrated an 8.2-cm expansile multilobulated heterogeneously enhancing intradural mass within the sacral spinal canal, extending into the bilateral S1 and left S2 foramina. Brain MRI depicted a 2.9-cm lobulated heterogeneously enhancing sellar-suprasellar solid and cystic mass expanding the sella and displacing the infundibulum to the right, with a normal-appearing pituitary gland inside the sella, and an extensive supratentorial and infratentorial superficial hemosiderosis. L5-S4 laminectomy and pterional craniotomy were performed for the resection of these lesions. Histopathologic examination revealed a sacral spinal cavernoma and a suprasellar hypothalamic-optochiasmatic pilocytic astrocytoma. CONCLUSION: The coexistence of hypothalamic-optochiasmatic pilocytic astrocytoma and occipital and sacral spinal cavernomas has not been reported previously. Especially for radiologically atypical suprasellar lesions, hypothalamic-optochiasmatic glioma should be included in the differential diagnosis of masses that can expand the sella. Besides previously postulated hypotheses of viral-induced or angiogenic factor-induced glial growth, we hypothesize that neoplastic origins of hypothalamic-optochiasmatic glioma might be due to the irritative mechanisms resulting from the frequent bleeds occurring from the spinal or cranial cavernoma.
[Mh] Termos MeSH primário: Astrocitoma/diagnóstico por imagem
Neoplasias Encefálicas/diagnóstico por imagem
Hemangioma Cavernoso do Sistema Nervoso Central/diagnóstico por imagem
Neoplasias Primárias Múltiplas/diagnóstico por imagem
Neoplasias da Coluna Vertebral/diagnóstico por imagem
[Mh] Termos MeSH secundário: Adulto
Astrocitoma/cirurgia
Neoplasias Encefálicas/cirurgia
Craniotomia/métodos
Hemangioma Cavernoso do Sistema Nervoso Central/cirurgia
Seres Humanos
Neoplasias Hipotalâmicas/diagnóstico por imagem
Neoplasias Hipotalâmicas/cirurgia
Laminectomia/métodos
Masculino
Neoplasias Primárias Múltiplas/cirurgia
Lobo Occipital/diagnóstico por imagem
Lobo Occipital/cirurgia
Neoplasias da Coluna Vertebral/cirurgia
Resultado do Tratamento
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Em] Mês de entrada:1708
[Cu] Atualização por classe:170830
[Lr] Data última revisão:
170830
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160324
[St] Status:MEDLINE


  8 / 659 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
PubMed Central Texto completo
Texto completo
[PMID]:26782815
[Au] Autor:Bataduwaarachchi VR; Tissera N
[Ad] Endereço:Department of Pharmacology and Pharmacy, Faculty of Medicine University of Colombo, PO Box 271, Kynsey Road, Colombo 8, Sri Lanka. vipbat7@yahoo.com.
[Ti] Título:Paraneoplastic limbic encephalitis with associated hypothalamitis mimicking a hyperdense hypothalamic tumor: a case report.
[So] Source:BMC Med Imaging;16:8, 2016 Jan 18.
[Is] ISSN:1471-2342
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Paraneoplastic limbic encephalitis is an uncommon association of common malignancies such as small cell lung carcinoma, testicular teratoma, and breast carcinoma. The nonspecific nature of the clinical presentation, lack of freely available diagnostic markers, and requirement for advanced imaging techniques pose a great challenge in the diagnosis of this disease in resource-poor settings. CARE PRESENTATION: A 64-year-old previously healthy Sri Lankan man was admitted to the general medical unit with subacute memory impairment regarding recent events that had occurred during the previous 3 weeks. Initial noncontrast computed tomography of the brain revealed a hyperdensity in the hypothalamic region surrounded by hypodensities extending toward the bilateral temporal lobes; these findings were consistent with a possible hypothalamic tumor with perilesional edema. The patient later developed cranial diabetes insipidus, which was further suggestive of hypothalamic disease. Interestingly, gadolinium-enhanced magnetic resonance imaging of the brain showed no such lesions; instead, it showed prominent T2-weighted signals in the inner mesial region, characteristic of encephalitis. The possibility of tuberculosis and viral encephalitis was excluded based on cerebrospinal fluid analysis results. Limbic encephalitis with predominant hypothalamitis was suspected based on the radiological pattern. Subsequent screening for underlying malignancy revealed a mass lesion in the right hilum on chest radiographs. Histological examination of the lesion showed small cell lung cancer of the "oat cell" variety. CONCLUSION: We suggest that the initial appearance of a hyperdensity in the hypothalamus region on noncontrast computed tomography is probably due to hyperemia caused by hypothalamitis. If hypothalamitis is predominant in a patient with paraneoplastic limbic encephalitis, magnetic resonance imaging will help to differentiate it from a hypothalamic secondary deposit. Limbic encephalitis should be considered in a patient with computed tomographic evidence of a central hyperdensity surrounded by bitemporal hypodensities. This pattern of identification will be useful for early diagnosis in resource-poor settings.
[Mh] Termos MeSH primário: Encéfalo/diagnóstico por imagem
Doenças Hipotalâmicas/diagnóstico
Encefalite Límbica/diagnóstico
[Mh] Termos MeSH secundário: Diagnóstico Diferencial
Seres Humanos
Neoplasias Hipotalâmicas/diagnóstico
Masculino
Meia-Idade
Sri Lanka
Tomografia Computadorizada por Raios X
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Em] Mês de entrada:1610
[Cu] Atualização por classe:170923
[Lr] Data última revisão:
170923
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160120
[St] Status:MEDLINE
[do] DOI:10.1186/s12880-016-0113-4


  9 / 659 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:26723291
[Au] Autor:Avecillas-Chasin JM; Budke M; Villarejo F
[Ad] Endereço:Department of Neurosurgery, Hospital Universitario Clínico San Carlos, Madrid, Spain.
[Ti] Título:Neuroendoscopic Intraventricular Biopsy in Children with Small Ventricles Using Frameless VarioGuide System.
[So] Source:World Neurosurg;87:136-42, 2016 Mar.
[Is] ISSN:1878-8769
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Endoscopic biopsy for intraventricular tumors in pediatric patients with small ventricles is a challenging procedure because of the risk of morbidity during the intraventricular approach. We describe the use of the VarioGuide system for intraventricular endoscopic biopsy in 9 consecutive pediatric patients with intraventricular lesions and small ventricular size. All patients had lesions in the anterior part of the third ventricle with a median frontal and occipital horn ratio of 0.33. Patients presented with growth failure (n = 4), visual disturbances (n = 4), and seizures (n = 1). The VarioGuide system consists of an ergonomic arm with 3 joints for gross adjustment. The 3 rotational joints on the distal side of the system are adjusted according to the angles of the planned trajectory. The endoscope is adjusted to the distal side of the VarioGuide and inserted through the ring, previously set for the diameter of the endoscope and for the planned trajectory. The accuracy of the trajectory and correct ventricular cannulation are confirmed under endoscopic guidance. The biopsy is carried out according to the standard technique. In all cases, the biopsy sample provided the definitive diagnosis. Diagnoses included germinomas in 4 patients, hamartoma in 1 patient, hypothalamic astrocytoma in 2 patients, and craniopharyngioma in 2 patients. The use of the VarioGuide system for intraventricular endoscopic biopsy is highly recommended for pediatric patients with small ventricle size. This technique may help minimize the risk of unnecessary brain damage during the entrance to small ventricles.
[Mh] Termos MeSH primário: Biópsia/métodos
Ventrículos Cerebrais/patologia
Ventrículos Cerebrais/cirurgia
Neuroendoscópios
Neuroendoscopia/métodos
[Mh] Termos MeSH secundário: Adolescente
Neoplasias do Ventrículo Cerebral/diagnóstico
Neoplasias do Ventrículo Cerebral/patologia
Ventrículos Cerebrais/anatomia & histologia
Criança
Pré-Escolar
Deficiências do Desenvolvimento/diagnóstico
Deficiências do Desenvolvimento/patologia
Feminino
Germinoma/diagnóstico
Germinoma/patologia
Transtornos do Crescimento/diagnóstico
Hamartoma/diagnóstico
Hamartoma/patologia
Seres Humanos
Neoplasias Hipotalâmicas/diagnóstico
Neoplasias Hipotalâmicas/patologia
Masculino
Estudos Retrospectivos
Transtornos da Visão/diagnóstico
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Em] Mês de entrada:1607
[Cu] Atualização por classe:160311
[Lr] Data última revisão:
160311
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160103
[St] Status:MEDLINE


  10 / 659 MEDLINE  
              first record previous record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:26661574
[Au] Autor:Dash C; Singla R; Garg K; Tandon V; Sharma BS
[Ad] Endereço:AIIMS, New Delhi, India.
[Ti] Título:Hypothalamic chiasmatic tuberculoma mimicking glioma.
[So] Source:Childs Nerv Syst;32(2):233-5, 2016 Feb.
[Is] ISSN:1433-0350
[Cp] País de publicação:Germany
[La] Idioma:eng
[Mh] Termos MeSH primário: Glioma/diagnóstico
Neoplasias Hipotalâmicas/diagnóstico
Hipotálamo/patologia
Tuberculoma Intracraniano/diagnóstico
[Mh] Termos MeSH secundário: Encéfalo/diagnóstico por imagem
Encéfalo/patologia
Pré-Escolar
Diagnóstico Diferencial
Seres Humanos
Hipotálamo/diagnóstico por imagem
Imagem por Ressonância Magnética
Masculino
Tomografia Computadorizada por Raios X
[Pt] Tipo de publicação:CASE REPORTS; LETTER
[Em] Mês de entrada:1611
[Cu] Atualização por classe:170926
[Lr] Data última revisão:
170926
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:151215
[St] Status:MEDLINE
[do] DOI:10.1007/s00381-015-2972-3



página 1 de 66 ir para página                         
   


Refinar a pesquisa
  Base de dados : MEDLINE Formulário avançado   

    Pesquisar no campo  
1  
2
3
 
           



Search engine: iAH v2.6 powered by WWWISIS

BIREME/OPAS/OMS - Centro Latino-Americano e do Caribe de Informação em Ciências da Saúde