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[PMID]:29254323
[Au] Autor:Ciappetta P; Taurone S; Spoletini M; Artico M
[Ad] Endereço:Department of Basic Medical Sciences, Neuroscience and Sensory Organs, University of Bari.
[Ti] Título:Anteriorly placed tumors to the conus: removal by interradicular window.
[So] Source:J Biol Regul Homeost Agents;31(4):1115-1118, 2017 Oct-Dec.
[Is] ISSN:0393-974X
[Cp] País de publicação:Italy
[La] Idioma:eng
[Ab] Resumo:Tumors anteriorly situated to the medullary conus are rarely encountered and represent a true surgical challenge. We examined the literature on this topic, concluding that there are no previous reports on alternative surgical techniques different to the traditional one. We report two cases of intradural extramedullary tumor operated on by a technique performed through a window opened between the spinal roots, which allows an easy, effective and useful resection. We describe a new operative technique which ensures a complete removal of these tumors and discuss clinical implications in the light of the available literature on this topic.
[Mh] Termos MeSH primário: Meningioma/cirurgia
Procedimentos Neurocirúrgicos/métodos
Recuperação de Função Fisiológica/fisiologia
Neoplasias da Medula Espinal/cirurgia
Medula Espinal/cirurgia
[Mh] Termos MeSH secundário: Adulto
Feminino
Seres Humanos
Imagem por Ressonância Magnética
Meningioma/diagnóstico por imagem
Meningioma/patologia
Meia-Idade
Medula Espinal/diagnóstico por imagem
Medula Espinal/patologia
Neoplasias da Medula Espinal/diagnóstico por imagem
Neoplasias da Medula Espinal/patologia
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180222
[Lr] Data última revisão:
180222
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171220
[St] Status:MEDLINE


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[PMID]:29252657
[Au] Autor:Kojima K; Iwanami A; Mikami S; Ishii K; Matsumoto M; Nakamura M
[Ad] Endereço:Departments of Orthopedic Surgery (K.K., A.I., K.I., M.M., and M.N.) and Pathology (S.M.), Keio University School of Medicine, Tokyo, Japan.
[Ti] Título:An Intramedullary Osteolipoma of the Upper Thoracic Spinal Cord: A Case Report.
[So] Source:JBJS Case Connect;6(3):e80, 2016 Jul-Sep.
[Is] ISSN:2160-3251
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:CASE: We present a rare case of an intramedullary osteolipoma without any extramedullary connections or coexisting spinal dysraphism. A 48-year-old woman presented with back pain and pain around the lateral aspect of the left thigh. Magnetic resonance imaging (MRI) revealed a heterogeneous hyperintense and hypointense region on T1 and T2-weighted imaging. A cavernous hemangioma was suspected, and the patient was admitted for surgical resection. The histological diagnosis was an intramedullary osteolipoma. CONCLUSION: MRI with fat suppression and computed tomography are recommended for the diagnosis of an intramedullary osteolipoma, but a definitive diagnosis requires histological examination.
[Mh] Termos MeSH primário: Lipoma/diagnóstico
Neoplasias da Medula Espinal/diagnóstico
[Mh] Termos MeSH secundário: Feminino
Seres Humanos
Lipoma/patologia
Meia-Idade
Neoplasias da Medula Espinal/patologia
Vértebras Torácicas/patologia
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180216
[Lr] Data última revisão:
180216
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171219
[St] Status:MEDLINE
[do] DOI:10.2106/JBJS.CC.16.00025


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[PMID]:29245277
[Au] Autor:Wang G; Guo F
[Ad] Endereço:aDepartment of NeurosurgerybDepartment of Neurosurgery, Key Laboratory of Neurosurgical Diseases, The First Affiliated Hospital of Zhengzhou University, ZhengZhou, HeNan Province, PR China.
[Ti] Título:Primary intramedullary primitive neuroectodermal tumor: A case report and review of the literature.
[So] Source:Medicine (Baltimore);96(49):e9001, 2017 Dec.
[Is] ISSN:1536-5964
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:RATIONALE: Primary spinal primitive neuroectodermal tumors (PNETs) are highly malignant tumors, which are extremely rare entities and primary intramedullary PNETs are extremely rare. Till now, only 24 cases of primary intramedullary PNET have been reported. PATIENT CONCERNS: A 26-year-old male presented with progressive low back and lower limb pain for 1 month. DIAGNOSES: Based on MRI and histopathological findings, he was diagnosed with primary intramedullary PNET. INTERVENTIONS: The patient was treated two times with microsurgical resections. OUTCOMES: Follow-up visit at 14 months after the first surgery showed that the patient is neurologically intact and free of disease. LESSONS: PNETs should be considered in the differential diagnosis of an intramedullary spinal cord tumor manifesting as progressive neurological deterioration.
[Mh] Termos MeSH primário: Tumores Neuroectodérmicos Primitivos/diagnóstico
Neoplasias da Medula Espinal/diagnóstico
[Mh] Termos MeSH secundário: Adulto
Seres Humanos
Vértebras Lombares/patologia
Imagem por Ressonância Magnética
Masculino
Tumores Neuroectodérmicos Primitivos/diagnóstico por imagem
Tumores Neuroectodérmicos Primitivos/cirurgia
Neoplasias da Medula Espinal/diagnóstico por imagem
Neoplasias da Medula Espinal/cirurgia
Vértebras Torácicas/patologia
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Em] Mês de entrada:1801
[Cu] Atualização por classe:180105
[Lr] Data última revisão:
180105
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:171217
[St] Status:MEDLINE
[do] DOI:10.1097/MD.0000000000009001


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[PMID]:28977080
[Au] Autor:Salomão R; Canêdo NHS; Abrão GP; Lima C; Acioly MA
[Ad] Endereço:Division of Neurosurgery, Universidade Federal do Rio de Janeiro (UFRJ), Rio de Janeiro, RJ, Brazil.
[Ti] Título:Foix-Alajouanine syndrome mimicking a spinal cord tumor.
[So] Source:Rev Assoc Med Bras (1992);63(7):564-565, 2017 Jul.
[Is] ISSN:1806-9282
[Cp] País de publicação:Brazil
[La] Idioma:eng
[Ab] Resumo:Subacute necrotizing myelopathy (SNM) or Foix-Alajouanine syndrome is a rare disease characterized by progressive neurological dysfunction caused by a spinal dural arteriovenous fistula (AVF). Radiological diagnosis is usually suspected when there is intramedullary nonspecific enhancement and perimedullary flow voids. Ring-enhancement is rarely reported in the scope of AVF, which poses a diagnostic challenge and raises the suspicion of a spinal cord tumor. In such situations, biopsy can be required and delay proper diagnosis. We report the case of a patient with SNM, who underwent biopsy on the assumption of it being a spinal cord tumor.
[Mh] Termos MeSH primário: Fístula Arteriovenosa/diagnóstico por imagem
Doenças da Medula Espinal/diagnóstico por imagem
Neoplasias da Medula Espinal/diagnóstico por imagem
[Mh] Termos MeSH secundário: Idoso
Angiografia
Fístula Arteriovenosa/patologia
Biópsia
Diagnóstico Diferencial
Feminino
Seres Humanos
Medula Espinal/diagnóstico por imagem
Medula Espinal/patologia
Doenças da Medula Espinal/patologia
Doenças da Medula Espinal/cirurgia
Neoplasias da Medula Espinal/patologia
Síndrome
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Em] Mês de entrada:1711
[Cu] Atualização por classe:171106
[Lr] Data última revisão:
171106
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171005
[St] Status:MEDLINE


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[PMID]:28885344
[Au] Autor:Sato T; Yonezawa I; Onda S; Yoshikawa K; Takano H; Shimamura Y; Okuda T; Kaneko K
[Ad] Endereço:Department of Orthopedic Surgery, Juntendo University School of Medicine, Tokyo, Japan.
[Ti] Título:Surgical treatment for lumbar hyperlordosis after resection of a spinal lipoma associated with spina bifida: A case report.
[So] Source:Medicine (Baltimore);96(36):e7895, 2017 Sep.
[Is] ISSN:1536-5964
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:RATIONALE: A hyperlordosis deformity of the lumbar spine is relatively rare, and surgical treatment has not been comprehensively addressed. In this case report, we describe the clinical presentation, surgical treatment, and medium-term follow-up of a patient presenting with a progressive lumbar hyperlordosis deformity after resection of a spinal lipoma associated with spina bifida. PATIENT CONCERNS: The patient was a 20-year-old woman presenting with a progressive hyperlordosis deformity of the lumbar spine associated with significant back pain (visual analog pain score of 89/100 mm), but with no neurological symptoms. DIAGNOSES: The lumbar lordosis (LL), measured on standing lateral view radiographs, was 114°, with a sagittal vertical axis (SVA) of -100 mm. The patient had undergone excision of a lipoma, associated with spina bifida of the lumbar spine, at 7 months of age.She was first evaluated at our hospital at 18 years of age for progressive spinal deformity and lumbago. INTERVENTIONS: An in situ fusion, from T5 to S1, using pedicle screws with bone graft obtained from the iliac crest, was performed. OUTCOMES: Postoperatively, the LL decreased to 93°, and the SVA decreased to -50 mm. The decision to not correct the hyperlordosis deformity fully was intentional. Seven years and 1 month postsurgery, the patient had no limitations in standing and walking and reported a pain score of 8/100 mm; there was no evidence of a loss of correction. LESSONS: Lumbar hyperlordosis after resection of a spinal lipoma associated with spina bifida is rare. Posterior fixation provided an effective treatment in this case. As the lumbar hyperlordosis deformity is often high, correction can be difficult. In this case, although the correction and fusion were performed in situ, there was no progression of either the deformity or the lumbago. Early detection remains an essential component of effective treatment, allowing correction when the spinal deformity is easily reversible.
[Mh] Termos MeSH primário: Lipoma/cirurgia
Lordose/etiologia
Lordose/cirurgia
Vértebras Lombares/cirurgia
Neoplasias da Medula Espinal/cirurgia
Disrafismo Espinal/cirurgia
[Mh] Termos MeSH secundário: Feminino
Seres Humanos
Lipoma/complicações
Lordose/diagnóstico por imagem
Vértebras Lombares/diagnóstico por imagem
Complicações Pós-Operatórias/diagnóstico por imagem
Complicações Pós-Operatórias/cirurgia
Neoplasias da Medula Espinal/complicações
Disrafismo Espinal/complicações
Adulto Jovem
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170918
[Lr] Data última revisão:
170918
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:170909
[St] Status:MEDLINE
[do] DOI:10.1097/MD.0000000000007895


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[PMID]:28885125
[Au] Autor:Nori S; Iwanami A; Yasuda A; Nagoshi N; Fujita N; Hikata T; Yagi M; Tsuji T; Watanabe K; Momoshima S; Matsumoto M; Nakamura M; Ishii K
[Ad] Endereço:Departments of 1 Orthopedic Surgery and.
[Ti] Título:Risk factor analysis of kyphotic malalignment after cervical intramedullary tumor resection in adults.
[So] Source:J Neurosurg Spine;27(5):518-527, 2017 Nov.
[Is] ISSN:1547-5646
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:OBJECTIVE A number of studies have reported that surgery for cervical intramedullary tumors via the posterior approach can result in postoperative sagittal malalignment of the cervical spine; however, the risk factors remain unclear. The purpose of this study was to investigate the changes in cervical spinal alignment after surgery for cervical intramedullary tumors in adults and to elucidate the risk factors for cervical spinal sagittal misalignment. METHODS Data for the period from April 2001 to December 2011 for all adults who had undergone surgery for cervical intramedullary spinal cord tumors at a single institution were retrospectively analyzed to determine the postoperative changes in cervical spine alignment. Patients younger than 20 years of age and those who required postoperative radiotherapy were excluded from the study. Patients were divided into 2 groups according to tumor location: upper tumor (U) group, in which the central region of the tumor was above the C-5 level; and lower tumor (L) group, in which the central region of the tumor was at or below the C-5 level. Changes in alignment of the cervical spine were measured on plain lateral radiographs. Data on atrophy of the deep extensor muscles (DEMs), tumor location, detachment of the DEMs from the C-2 spinous process, the C2-7 angle before surgery, patient age at surgery, tumor histology, patient sex, tumor size, and number of laminae affected were reviewed for each patient, and the correlation of each of these factors with cervical spinal malalignment was evaluated using statistical analysis. RESULTS The 54 adults eligible for analysis had a mean age of 49.1 years. Ependymoma was the most common cervical intramedullary tumor (63.0%) in this series. In the tumor location U group, the kyphotic angle of the C2-7 spinal segments increased after surgery (-5.8° ± 2.8°). In contrast, in the L group, the C2-7 lordotic angle increased after surgery (6.4° ± 2.6°). In the univariate analysis, atrophy of the DEMs, detachment of the DEMs from the C-2 spinous process, and an upper cervical location of the tumor were identified as factors significantly correlated with the development of cervical spinal kyphosis after surgery. Multiple linear regression analysis revealed the following as risk factors for kyphotic change of the cervical spine after surgery: 1) atrophy of the DEMs after surgery (ß = -0.54, p < 0.01), and 2) detachment of the DEMs from the C-2 spinous process (ß = -0.37, p < 0.01). CONCLUSIONS Atrophy of the DEMs after surgery and detachment of the DEMs from the C-2 spinous process are directly related to the risk of cervical spinal kyphosis after surgery for cervical intramedullary tumors in adults. Therefore, preservation of the DEMs, especially those attached to the C-2 spinous process, is important for the prevention of kyphotic malalignment of the cervical spine after surgery for intramedullary tumors.
[Mh] Termos MeSH primário: Vértebras Cervicais/cirurgia
Cifose/etiologia
Complicações Pós-Operatórias
Neoplasias da Medula Espinal/cirurgia
[Mh] Termos MeSH secundário: Adulto
Idoso
Vértebras Cervicais/diagnóstico por imagem
Ependimoma/diagnóstico por imagem
Ependimoma/cirurgia
Feminino
Seres Humanos
Cifose/diagnóstico
Cifose/epidemiologia
Modelos Lineares
Lordose/diagnóstico
Lordose/epidemiologia
Lordose/etiologia
Masculino
Meia-Idade
Complicações Pós-Operatórias/diagnóstico
Complicações Pós-Operatórias/epidemiologia
Estudos Retrospectivos
Fatores de Risco
Neoplasias da Medula Espinal/diagnóstico por imagem
Adulto Jovem
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Em] Mês de entrada:1711
[Cu] Atualização por classe:171103
[Lr] Data última revisão:
171103
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170909
[St] Status:MEDLINE
[do] DOI:10.3171/2017.4.SPINE16956


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[PMID]:28759666
[Au] Autor:Pathmanaban ON; Sadler KV; Kamaly-Asl ID; King AT; Rutherford SA; Hammerbeck-Ward C; McCabe MG; Kilday JP; Beetz C; Poplawski NK; Evans DG; Smith MJ
[Ad] Endereço:Department of Neurosurgery, Manchester Centre for Clinical Neuroscience, Salford Royal National Health Service Foundation Trust, Manchester Academic Health Science Centre, University of Manchester, Manchester, England.
[Ti] Título:Association of Genetic Predisposition With Solitary Schwannoma or Meningioma in Children and Young Adults.
[So] Source:JAMA Neurol;74(9):1123-1129, 2017 Sep 01.
[Is] ISSN:2168-6157
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Importance: Meningiomas and schwannomas are usually sporadic, isolated tumors occurring in adults older than 60 years and are rare in children and young adults. Multiple schwannomas and/or meningiomas are more frequently associated with a tumor suppressor syndrome and, accordingly, trigger genetic testing, whereas solitary tumors do not. Nevertheless, apparently sporadic tumors in young patients may herald a genetic syndrome. Objective: To determine the frequency of the known heritable meningioma- or schwannoma-predisposing mutations in children and young adults presenting with a solitary meningioma or schwannoma. Design, Setting, and Participants: Using the database of the Manchester Centre for Genomic Medicine, this cohort study analyzed lymphocyte DNA from young individuals prospectively referred to the clinic for genetic testing between January 1, 1990, and December 31, 2016, on presentation with a single meningioma (n = 42) or schwannoma (n = 135) before age 25 years. Sequencing data were also examined from an additional 39 patients with neurofibromatosis type 2 who were retrospectively identified as having a solitary tumor before age 25 years. Patients with schwannoma were screened for NF2, SMARCB1, and LZTR1 gene mutations, while patients with meningioma were screened for NF2, SMARCB1, SMARCE1, and SUFU. Main Outcomes and Measures: The type of underlying genetic mutation, or lack of a predisposing mutation, was associated with the presenting tumor type and subsequent development of additional tumors or other features of known schwannoma- and meningioma-predisposing syndromes. Results: In 2 cohorts of patients who presented with an isolated meningioma (n = 42; median [range] age, 11 [1-24] years; 22 female) or schwannoma (n = 135; median [range] age, 18 [0.2-24] years; 60 female) before age 25 years, 16 of 42 patients (38%) had a predisposing mutation to meningioma and 27 of 135 patients (20%) to schwannoma, respectively. In the solitary meningioma cohort, 34 of 63 patients (54%) had a constitutional mutation in a known meningioma predisposition gene. Twenty-five of 63 patients (40%) had a constitutional NF2 mutation, and 9 (14%) had a constitutional SMARCE1 mutation. In the cohort of those who developed a solitary schwannoma before age 25 years, 44 of 153 patients (29%) had an identifiable genetic predisposition. Twenty-four patients (55%) with a spinal schwannoma had a constitutional mutation, while only 20 (18%) with a cranial schwannoma had a constitutional predisposition (P < .001). Of 109 cranial schwannomas, 106 (97.2%) were vestibular. Four of 106 people (3.8%) with a cranial schwannoma had an LZTR1 mutation (3 were vestibular schwannomas and 1 was a nonvestibular schwannoma), and 9 (8.5%) had an NF2 mutation. Conclusions and Relevance: A significant proportion of young people with an apparently sporadic solitary meningioma or schwannoma had a causative predisposition mutation. This finding has important clinical implications because of the risk of additional tumors and the possibility of familial disease. Young patients presenting with a solitary meningioma or schwannoma should be referred for genetic testing.
[Mh] Termos MeSH primário: Neoplasias Encefálicas/genética
Predisposição Genética para Doença
Neoplasias Meníngeas/genética
Meningioma/genética
Neurilemoma/genética
Neoplasias da Medula Espinal/genética
[Mh] Termos MeSH secundário: Adolescente
Adulto
Criança
Pré-Escolar
Estudos de Coortes
Seres Humanos
Lactente
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171004
[Lr] Data última revisão:
171004
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:170801
[St] Status:MEDLINE
[do] DOI:10.1001/jamaneurol.2017.1406


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[PMID]:28732416
[Au] Autor:Prasad GL
[Ad] Endereço:Department of Neurosurgery, Kasturba Medical College, Manipal University, Manipal, India. Electronic address: lakshmi.prasad@maniapl.edu.
[Ti] Título:Primary Spinal Cord Glioblastoma Multiforme: A Rare but Uniformly Fatal Neoplasm.
[So] Source:World Neurosurg;104:1020-1021, 2017 08.
[Is] ISSN:1878-8769
[Cp] País de publicação:United States
[La] Idioma:eng
[Mh] Termos MeSH primário: Glioblastoma
Medula Espinal
[Mh] Termos MeSH secundário: Neoplasias Encefálicas
Evolução Fatal
Seres Humanos
Neoplasias da Medula Espinal
[Pt] Tipo de publicação:LETTER; COMMENT
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170904
[Lr] Data última revisão:
170904
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170723
[St] Status:MEDLINE


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[PMID]:28705700
[Au] Autor:Koustais S; O'Halloran PJ; Hassan A; Brett F; Young S
[Ad] Endereço:Department of Neurosurgery, Beaumont Hospital, Dublin, Ireland. Electronic address: stavroskoustais@beaumont.ie.
[Ti] Título:Incidental Primary Intradural Carcinoid Tumor in a Patient with Lumbar Radiculopathy.
[So] Source:World Neurosurg;105:1042.e11-1042.e14, 2017 Sep.
[Is] ISSN:1878-8769
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Carcinoid tumors are neuroendocrine neoplasms derived from enterochromaffin cells. Central nervous system involvement is rare. The reported cases include metastases to brain or spinal cord, and primary skeletal or extradural disease resulting in compressive myeloradiculopathy. There are 2 previously reported cases of primary intradural extramedullary carcinoid tumor, presenting with compressive symptoms. We report the first case of primary incidental intradural extramedullary carcinoid tumor. CASE DESCRIPTION: A 68-year-old man was complaining of a 2-month history of left-sided back pain and sciatica; however, he presented with acutely worse symptoms of severe left sciatica. There was no sphincter dysfunction nor power deficit on examination. A magnetic resonance imaging (MRI) scan of the lumbar spine revealed an L4-5 central disk protrusion causing left L5 nerve root compression, and a heterogeneous enhancing intradural mass at the L2-3 level displacing the cauda equina. An L4-5 microdiscectomy followed by an L2-3 laminectomy and resection of the intradural mass was performed. There was a postoperative left S1 paresthesia that was managed medically; however, the postoperative period was unremarkable. A postoperative MRI of the lumbar spine showed complete resection of the mass. A staging scan revealed an incidental thyroid nodule; however, there was no other disease burden. Histopathology of the resected specimen revealed a primary spinal carcinoid tumor. CONCLUSIONS: To our knowledge, this is the first reported case of incidental primary intradural spinal carcinoid tumor. Even though intradural spinal carcinoid tumors are exceedingly rare, they should be included in the differential diagnosis of enhancing intradural lesions.
[Mh] Termos MeSH primário: Tumor Carcinoide/diagnóstico por imagem
Achados Incidentais
Vértebras Lombares/diagnóstico por imagem
Radiculopatia/diagnóstico por imagem
Neoplasias da Medula Espinal/diagnóstico por imagem
[Mh] Termos MeSH secundário: Idoso
Tumor Carcinoide/complicações
Tumor Carcinoide/cirurgia
Seres Humanos
Vértebras Lombares/cirurgia
Masculino
Radiculopatia/complicações
Radiculopatia/cirurgia
Neoplasias da Medula Espinal/complicações
Neoplasias da Medula Espinal/cirurgia
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171003
[Lr] Data última revisão:
171003
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170715
[St] Status:MEDLINE


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[PMID]:28674582
[Au] Autor:Sahli M; Hemmaoui B; Benariba F
[Ad] Endereço:Department of Head and Neck Surgery, Military Hospital Mohammed V, Rabat, Morocco.
[Ti] Título:Intramedullary spinal cord metastasis from laryngeal carcinoma: case report and review of literature.
[So] Source:Pan Afr Med J;26:189, 2017.
[Is] ISSN:1937-8688
[Cp] País de publicação:Uganda
[La] Idioma:eng
[Ab] Resumo:Laryngeal cancer metastases are relatively rare and mainly affect the lung. The medullary localization remains exceptional. We report the case of a patient followed for operated laryngeal cancer and whose oncologic control revealed a medullary localization. A patient followed for squamous cell carcinoma of the larynx, treated in 2010 by a partial surgery whose endoscopic control at 5 years revealed the presence of right arytenoid edema without suspicious lesions, multiple biopsies were made and which returned negative. A month later, the patient presented a rebel cervical spine pain and a feeling of heaviness of the upper limbs, for which a radiological assessment was done finally objectifying a right hypopharyngeal process and a suspicious right internal jugular lymphadenopathy (biopsy confirmed the squamous type), as well as an intramedullary metastasis. This case is an illustration of an exceptional evolution of this type of cancer and a are metastatic localization difficult to highlight, which leads us to ask the question on the need of simultaneous and systematic radiological and endoscopic control treatment for operated laryngeal cancer.
[Mh] Termos MeSH primário: Carcinoma de Células Escamosas/patologia
Neoplasias Laríngeas/patologia
Neoplasias da Medula Espinal/patologia
[Mh] Termos MeSH secundário: Idoso
Biópsia
Carcinoma de Células Escamosas/diagnóstico
Carcinoma de Células Escamosas/cirurgia
Seres Humanos
Neoplasias Laríngeas/diagnóstico
Neoplasias Laríngeas/cirurgia
Masculino
Neoplasias da Medula Espinal/diagnóstico
Neoplasias da Medula Espinal/secundário
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE; REVIEW
[Em] Mês de entrada:1707
[Cu] Atualização por classe:170717
[Lr] Data última revisão:
170717
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170705
[St] Status:MEDLINE
[do] DOI:10.11604/pamj.2017.26.189.11507



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