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[PMID]:29429179
[Au] Autor:Zhao SY; Ma YH; Yin Z; Zhan XX; Cheng RC; Qian J
[Ad] Endereço:Department of Thyroid Surgery, First Affiliated Hospital of Kunming Medical University, Kunming 650032, China.
[Ti] Título:[Evaluation of central lymph node dissection for papillary thyroid carcinoma in cN0 T1/T2].
[So] Source:Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi;53(2):105-109, 2018 Feb 07.
[Is] ISSN:1673-0860
[Cp] País de publicação:China
[La] Idioma:chi
[Ab] Resumo:To evaluate the application of the central lymph node dissection (CLND) for papillary thyroid carcinoma (PTC) in cN0 T1/T2. Retrospective analysis of 532 cases with PTC in cN0 T1/T2 who underwent CLND between October 2014 and September 2016 in the Department of Thyroid Surgery, the First Affiliated Hospital of the Kunming Medical University. The incidence of central lymph node (CLN) metastasis and risk factors were analyzed. CLN metastasis rates: 41.2% (42/102) in males vs 34.9% (150/430) in females, =0.252; 33.9% (116/342) in single focal carcinoma vs 40.4% (74/183) in multifocal carcinoma, =0.157; 44.0% (125/284) in patients with 45 years old or less vs 27.0% (67/248) in patients more than 45 years old, =0.000; 30.3% (113/373) in microcarcinoma vs 50.9% (81/159) in non-microcarcinoma, =0.000.In unilateral lesions, ipsilateral CLN metastasis was correlated with the tumor diameter ( =0.012), but not with the number of lesions ( =0.653). also contralateral CLN metastasis was correlated with the tumor diameter ( =0.000), but not with the number of lesions ( =0.815). For the left or right unilateral single focal lesion, the tumor diameter was not correlated with the metastasis of the posterior to right recurrent laryngeal nerve central lymph nodes (LN-prRLN-CLN) ( =0.652, =0.088). But in bilateral multifocal carcinoma the tumor diameter was correlated with metastasis of LN-prRLN-CLN ( =0.039). Prophylactic CLND is reasonable for PTC in cN0 T1/T2. A bilateral CLND should be conducted for patients with bilateral multi-focus cancer and unilateral or bilateral non-microcarcinoma, especially in patients more than 45 years old. For unilateral single focal microcarcinoma on the right, the content of CLND should be from laryngeal nerve on right center to posterior branche; for unilateral single focal microcarcinoma on the left side, the left CLND should be conducted. An ipsilateral CLND can be considered in patients with unilateral multifocal microcarcinoma, and generally a routine dissection of the LN-prRLN-CLN is not required, however for bilateral non-microcarcinoma and the the non-microcarcinoma on the right side, the LN-prRLN-CLN dissection should be conducted.
[Mh] Termos MeSH primário: Carcinoma Papilar/cirurgia
Excisão de Linfonodo/métodos
Linfonodos/cirurgia
Neoplasias da Glândula Tireoide/cirurgia
[Mh] Termos MeSH secundário: Adulto
Carcinoma Papilar/secundário
Neoplasias dos Nervos Cranianos/secundário
Feminino
Seres Humanos
Nervos Laríngeos
Linfonodos/patologia
Metástase Linfática
Masculino
Meia-Idade
Nervo Laríngeo Recorrente
Estudos Retrospectivos
Fatores de Risco
Neoplasias da Glândula Tireoide/patologia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1803
[Cu] Atualização por classe:180307
[Lr] Data última revisão:
180307
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180213
[St] Status:MEDLINE
[do] DOI:10.3760/cma.j.issn.1673-0860.2018.02.005


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[PMID]:28693694
[Au] Autor:Wang T; Ma L; Lou X; Bu B
[Ad] Endereço:Department of Radiology, Chinese PLA General Hospital, Beijing 100853, China.
[Ti] Título:Trigeminal Ganglioneuroma in the Middle-posterior Cranial Fossa: a Case Report.
[So] Source:Chin Med Sci J;32(2):123-8, 2017 Jun 10.
[Is] ISSN:1001-9294
[Cp] País de publicação:China
[La] Idioma:eng
[Mh] Termos MeSH primário: Fossa Craniana Posterior
Neoplasias dos Nervos Cranianos/diagnóstico
Ganglioneuroma/diagnóstico
Neoplasias da Base do Crânio/diagnóstico
Gânglio Trigeminal
[Mh] Termos MeSH secundário: Neoplasias dos Nervos Cranianos/patologia
Ganglioneuroma/patologia
Seres Humanos
Masculino
Meia-Idade
Neoplasias da Base do Crânio/patologia
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171026
[Lr] Data última revisão:
171026
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170712
[St] Status:MEDLINE
[do] DOI:10.24920/J1001-9294.2017.016


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[PMID]:28602924
[Au] Autor:Santander XA; Cotúa CE; Saldaña C
[Ad] Endereço:Department of Neurosurgery, Puerta de Hierro University Hospital, Majadahonda, Madrid, Spain. Electronic address: xavier.santander@gmail.com.
[Ti] Título:Spontaneous Regression of a Hypoglossal Neurinoma: Case Report and Review of the Literature.
[So] Source:World Neurosurg;105:1033.e7-1033.e9, 2017 Sep.
[Is] ISSN:1878-8769
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Hypoglossal neurinomas are very rare intracranial tumors. The management choices include surgery, as the gold standard, and radiosurgery or a combination of both. Little is known about this condition and the behavior of this tumor. CASE DESCRIPTION: A 54-year-old woman presented with a right 12th nerve neurinoma with ipsilateral hemiatrophy of the tongue and spontaneous regression after 1 year of follow-up. CONCLUSIONS: Our case highlights the importance of considering careful observation and diligent follow-up as a treatment option, as these lesions can show spontaneous regression with no invasive approaches.
[Mh] Termos MeSH primário: Neoplasias dos Nervos Cranianos/cirurgia
Neurilemoma/cirurgia
[Mh] Termos MeSH secundário: Atrofia/patologia
Neoplasias dos Nervos Cranianos/diagnóstico por imagem
Feminino
Seres Humanos
Imagem por Ressonância Magnética
Meia-Idade
Neurilemoma/diagnóstico por imagem
Tomografia Computadorizada por Raios X
Língua/diagnóstico por imagem
Língua/patologia
Língua/cirurgia
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE; REVIEW
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171004
[Lr] Data última revisão:
171004
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170613
[St] Status:MEDLINE


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[PMID]:28434965
[Au] Autor:Nesvick CL; Perry A; Graffeo CS; Raghunathan A; Hammack JE; Van Gompel JJ
[Ad] Endereço:Department of Neurologic Surgery, Mayo Clinic, Rochester, Minnesota, USA.
[Ti] Título:Trochlear Schwannoma Presenting with Isolated Trigeminal Neuralgia.
[So] Source:World Neurosurg;103:951.e13-951.e20, 2017 Jul.
[Is] ISSN:1878-8769
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Schwannomas arising from the cranial nerves controlling extraocular eye movements are very rare and usually present with some degree of diplopia. CASE PRESENTATION: We report a 50-year-old woman who presented with isolated left-sided trigeminal neuralgia of 6 months' duration. Imaging demonstrated a homogeneously enhancing mass in the left ambient cistern, and the patient was brought to the operating room for resection. A retrosigmoid approach was used, and the mass was directly visualized arising from the trochlear nerve and compressing the dorsal root entry zone of the trigeminal nerve. A gross total resection of the mass was achieved, and microvascular decompression of the trigeminal nerve was performed. The tumor was pathologically confirmed as a schwannoma. At 3-month follow-up, the patient's facial pain was resolved, and her extraocular eye movements were intact. CONCLUSIONS: A total of 32 pathology-confirmed cases of trochlear schwannoma have been previously reported in the English-language literature. Most of these tumors arose from the cisternal segment of the nerve, and most patients presented with frank trochlear nerve palsy on exam. We report the first case of trochlear schwannoma presenting with isolated trigeminal neuralgia.
[Mh] Termos MeSH primário: Neoplasias dos Nervos Cranianos/complicações
Neurilemoma/complicações
Neuralgia do Trigêmeo/etiologia
Doenças do Nervo Troclear/complicações
[Mh] Termos MeSH secundário: Neoplasias dos Nervos Cranianos/diagnóstico por imagem
Neoplasias dos Nervos Cranianos/patologia
Neoplasias dos Nervos Cranianos/cirurgia
Feminino
Seres Humanos
Imagem por Ressonância Magnética
Cirurgia de Descompressão Microvascular
Meia-Idade
Neurilemoma/diagnóstico por imagem
Neurilemoma/patologia
Neurilemoma/cirurgia
Procedimentos Neurocirúrgicos
Neuralgia do Trigêmeo/cirurgia
Doenças do Nervo Troclear/diagnóstico por imagem
Doenças do Nervo Troclear/patologia
Doenças do Nervo Troclear/cirurgia
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170925
[Lr] Data última revisão:
170925
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170425
[St] Status:MEDLINE


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[PMID]:28346648
[Au] Autor:Nadimi S; Leonetti JP; Marzo SJ; Anderson DE; Mahmood G; Bumgarner D
[Ad] Endereço:Department of Otolaryngology-Head and Neck Surgery, Loyola University Medical Center, 2160 S. First Ave., Maywood, IL 60153, USA.
[Ti] Título:Glomus faciale tumors: A report of 3 cases and literature review.
[So] Source:Ear Nose Throat J;96(3):E7-E12, 2017 Mar.
[Is] ISSN:1942-7522
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Our objectives in reporting this case series are to familiarize readers with the rare occurrence of paragangliomas originating along the facial nerve and to provide a literature review. We describe 3 such cases that occurred at our tertiary care academic medical center. Two women and 1 man presented with a tumor adjacent to the vertical segment of the facial nerve. The first patient, a 48-year-old woman, presented with what appeared to be a parotid tumor at the stylomastoid foramen; she underwent a parotidectomy, transmastoid facial nerve decompression, and a shave biopsy of the tumor. The second patient, a 66-year-old man, underwent surgery via a postauricular infratemporal fossa approach, and a complete tumor resection was achieved. The third patient, a 56-year-old woman, presented with a middle ear mass; she underwent complete tumor removal through a transmastoid transcanal approach. All 3 patients exhibited normal facial nerve function both before and after surgery. Paragangliomas of the facial nerve are extremely rare, and their signs and symptoms are unlike those of any other temporal bone glomus tumors. Management options include surgical resection, radiologic surveillance, and radiotherapy. The facial nerve can be spared in selected cases.
[Mh] Termos MeSH primário: Neoplasias dos Nervos Cranianos/patologia
Doenças do Nervo Facial/patologia
Tumor Glômico/patologia
Paraganglioma/patologia
[Mh] Termos MeSH secundário: Adulto
Neoplasias dos Nervos Cranianos/cirurgia
Nervo Facial/patologia
Nervo Facial/cirurgia
Doenças do Nervo Facial/cirurgia
Feminino
Tumor Glômico/cirurgia
Seres Humanos
Masculino
Meia-Idade
Procedimentos Neurocirúrgicos/métodos
Paraganglioma/cirurgia
Resultado do Tratamento
Adulto Jovem
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE; REVIEW
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171019
[Lr] Data última revisão:
171019
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170328
[St] Status:MEDLINE


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[PMID]:28193203
[Au] Autor:Dewan R; Pemov A; Dutra AS; Pak ED; Edwards NA; Ray-Chaudhury A; Hansen NF; Chandrasekharappa SC; Mullikin JC; Asthagiri AR; Heiss JD; Stewart DR; Germanwala AV; NISC Comparative Sequencing Program
[Ad] Endereço:Surgical Neurology Branch, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, USA.
[Ti] Título:First insight into the somatic mutation burden of neurofibromatosis type 2-associated grade I and grade II meningiomas: a case report comprehensive genomic study of two cranial meningiomas with vastly different clinical presentation.
[So] Source:BMC Cancer;17(1):127, 2017 02 13.
[Is] ISSN:1471-2407
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Neurofibromatosis type 2 (NF2) is a rare autosomal dominant nervous system tumor predisposition disorder caused by constitutive inactivation of one of the two copies of NF2. Meningiomas affect about one half of NF2 patients, and are associated with a higher disease burden. Currently, the somatic mutation landscape in NF2-associated meningiomas remains largely unexamined. CASE PRESENTATION: Here, we present an in-depth genomic study of benign and atypical meningiomas, both from a single NF2 patient. While the grade I tumor was asymptomatic, the grade II tumor exhibited an unusually high growth rate: expanding to 335 times its initial volume within one year. The genomes of both tumors were examined by whole-exome sequencing (WES) complemented with spectral karyotyping (SKY) and SNP-array copy-number analyses. To better understand the clonal composition of the atypical meningioma, the tumor was divided in four sections and each section was investigated independently. Both tumors had second copy inactivation of NF2, confirming the central role of the gene in meningioma formation. The genome of the benign tumor closely resembled that of a normal diploid cell and had only one other deleterious mutation (EPHB3). In contrast, the chromosomal architecture of the grade II tumor was highly re-arranged, yet uniform among all analyzed fragments, implying that this large and fast growing tumor was composed of relatively few clones. Besides multiple gains and losses, the grade II meningioma harbored numerous chromosomal translocations. WES analysis of the atypical tumor identified deleterious mutations in two genes: ADAMTSL3 and CAPN5 in all fragments, indicating that the mutations were present in the cell undergoing fast clonal expansion CONCLUSIONS: This is the first WES study of NF2-associated meningiomas. Besides second NF2 copy inactivation, we found low somatic burden in both tumors and high level of genomic instability in the atypical meningioma. Genomic instability resulting in altered gene dosage and compromised structural integrity of multiple genes may be the primary reason of the high growth rate for the grade II tumor. Further study of ADAMTSL3 and CAPN5 may lead to elucidation of their molecular implications in meningioma pathogenesis.
[Mh] Termos MeSH primário: Neoplasias dos Nervos Cranianos/genética
Genes da Neurofibromatose 2
Genômica/métodos
Neoplasias Meníngeas/genética
Meningioma/genética
Mutação/genética
[Mh] Termos MeSH secundário: Adulto
Neoplasias dos Nervos Cranianos/patologia
Neoplasias dos Nervos Cranianos/cirurgia
Feminino
Genótipo
Seres Humanos
Neoplasias Meníngeas/patologia
Neoplasias Meníngeas/cirurgia
Meningioma/patologia
Meningioma/cirurgia
Gradação de Tumores
Prognóstico
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE; RESEARCH SUPPORT, N.I.H., EXTRAMURAL; RESEARCH SUPPORT, N.I.H., INTRAMURAL
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171121
[Lr] Data última revisão:
171121
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170215
[St] Status:MEDLINE
[do] DOI:10.1186/s12885-017-3127-6


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[PMID]:28085688
[Au] Autor:de Heer LM; Teding van Berkhout F; Priesterbach-Ackley LP; Buijsrogge MP
[Ad] Endereço:From the Departments of *Cardiothoracic Surgery, †Pulmonology, and ‡Pathology, University Medical Central Utrecht, Utrecht, The Netherlands.
[Ti] Título:Schwannoma of the Recurrent Laryngeal Nerve: A Rare Entity.
[So] Source:Innovations (Phila);12(1):64-66, 2017 Jan/Feb.
[Is] ISSN:1559-0879
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Neurogenic tumors are the most common posterior mediastinal tumors in adults. Schwannomas originating from the recurrent laryngeal nerve are rare. The present study describes a 46-year-old man with a tumor in the left superior mediastinum. Because of the narrow relationship with the aorta and the left pulmonary artery, the tumor was excised by left-sided minithoracotomy. The tumor, a schwannoma, originated from and encased the left recurrent laryngeal nerve. Six months after surgery, the patient was free of recurrence without symptoms other than hoarseness. "Additional imaging by magnetic resonance imaging could raise the probability of a neurogenic origin of the mass, eventually leading to collaboration with the neurosurgeon in this case."
[Mh] Termos MeSH primário: Neoplasias dos Nervos Cranianos/cirurgia
Neurilemoma/cirurgia
Nervo Laríngeo Recorrente/cirurgia
[Mh] Termos MeSH secundário: Rouquidão/etiologia
Seres Humanos
Masculino
Meia-Idade
Doenças Raras
Cirurgia Torácica Vídeoassistida/efeitos adversos
Cirurgia Torácica Vídeoassistida/métodos
Resultado do Tratamento
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Em] Mês de entrada:1703
[Cu] Atualização por classe:170308
[Lr] Data última revisão:
170308
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170114
[St] Status:MEDLINE
[do] DOI:10.1097/IMI.0000000000000334


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[PMID]:28043883
[Au] Autor:Khan N; Michael A; Choucair A; Bit-Ivan E
[Ad] Endereço:Department of Neurology, Southern Illinois University School of Medicine, Springfield, Illinois, USA. Electronic address: nadeem.israr.khan@gmail.com.
[Ti] Título:Trigeminal Ganglioneuroma: A Rare Case of Trigeminal Neuralgia Caused by Cerebellopontine Angle Tumor.
[So] Source:World Neurosurg;99:811.e7-811.e10, 2017 Mar.
[Is] ISSN:1878-8769
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Intracranial ganglioneuromas are very rare benign tumors of neural crest origin and generally arise from the peripheral nervous system or adrenal glands. Very few cases of intracranial ganglioneuroma arising from the trigeminal nerve have been reported in the literature, all in East Asia. CASE DESCRIPTION: A 52-year-old male presented to his primary care physician for evaluation of right facial and periorbital pain for over 18 months. He also reported a two-week history of diplopia with right lateral gaze, which resolved spontaneously. An MRI brain with and without contrast revealed a 3.0 × 2.6 × 2.4 cm enhancing extra-axial mass involving right Meckel's cave with a posterior 1.0 × 1.4 cm lobular component protruding into the prepontine cistern. The patient underwent a right middle fossa craniotomy for a subtemporal surgical resection of the tumor. Histologic section of the tumor demonstrated mature ganglion cells with surrounding satellite cells in a schwannian rich stroma, consistent with mature type ganglioneuroma. CONCLUSIONS: To the best of our knowledge, this is the sixth case of trigeminal ganglioneuroma; however, it is the first case reported in the United States.
[Mh] Termos MeSH primário: Neoplasias dos Nervos Cranianos/diagnóstico por imagem
Ganglioneuroma/diagnóstico por imagem
Nervo Trigêmeo/diagnóstico por imagem
Neuralgia do Trigêmeo/etiologia
[Mh] Termos MeSH secundário: Ângulo Cerebelopontino/diagnóstico por imagem
Neoplasias dos Nervos Cranianos/complicações
Neoplasias dos Nervos Cranianos/cirurgia
Ganglioneuroma/complicações
Ganglioneuroma/cirurgia
Seres Humanos
Imagem por Ressonância Magnética
Masculino
Meia-Idade
Nervo Trigêmeo/cirurgia
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170918
[Lr] Data última revisão:
170918
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170104
[St] Status:MEDLINE


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[PMID]:27916722
[Au] Autor:Takase H; Araki K; Seki S; Takase K; Murata H; Kawahara N
[Ad] Endereço:Department of Neurosurgery, Graduate School of Medicine, Yokohama City University, Yokohama, Japan. Electronic address: htakase@yokohama-cu.ac.jp.
[Ti] Título:Unique Diagnostic Features and Surgical Strategy for Intracranial Carotid Sympathetic Plexus Schwannoma: Case Report and Literature Review.
[So] Source:World Neurosurg;98:876.e1-876.e8, 2017 Feb.
[Is] ISSN:1878-8769
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Intracranial carotid sympathetic plexus schwannoma (CSPS) is extremely rare; thus differential diagnostic criteria, optimal surgical strategies, and even a precise definition are lacking. Here we describe a case of CSPS and propose a definition and classification for previously reported cases. CASE DESCRIPTION: A 54-year-old man presented with hypacusis and abducens nerve palsy. Radiologic examinations revealed a well-enhanced mass at the right medial temporal base with erosion of the petrous apex and intact perilesional cortical bone. Preoperative findings, such as spontaneous improvement of diplopia, absence of xerophthalmia or facial palsy, and laterally displaced internal carotid artery (ICA), suggested the atypical origins of the petrous apex schwannoma. The tumor was exposed using the subtemporal extradural approach and completely resected. Intact foramen ovale, rostrolateral displacement of the greater superficial petrosal nerve within the outer membrane of the tumor, eroded petrous apex and carotid canal, superolaterally displaced ICA, and lack of an obvious tumor attachment to any of the suspected nerves suggested that the tumor originated from the carotid sympathetic plexus of the petrous ICA. The patient fully recovered without neurological complications. CONCLUSIONS: Preoperative diagnosis of petrous apex schwannoma is difficult: characteristic findings such as diplopia, hypacusis, and laterally displaced ICA may help. In addition, assessment of the relationship between the tumor and cavernous sinus could be useful in the determination of the surgical approach. Complete resection with good clinical outcome could be expected using Dolenc's approach (type A) and by the middle fossa extradural approach (type B) for intracavernous and extracavernous CSPS, respectively.
[Mh] Termos MeSH primário: Neoplasias dos Nervos Cranianos/diagnóstico por imagem
Neoplasias dos Nervos Cranianos/cirurgia
Neurilemoma/diagnóstico por imagem
Neurilemoma/cirurgia
[Mh] Termos MeSH secundário: Angiografia Digital
Seio Cavernoso/diagnóstico por imagem
Seio Cavernoso/cirurgia
Seres Humanos
Imagem por Ressonância Magnética
Masculino
Meia-Idade
Tomógrafos Computadorizados
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE; REVIEW
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170915
[Lr] Data última revisão:
170915
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161206
[St] Status:MEDLINE


  10 / 3758 MEDLINE  
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[PMID]:27899468
[Au] Autor:Patel MA; Eytan DF; Bishop J; Califano JA
[Ad] Endereço:1 Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
[Ti] Título:Favorable Swallowing Outcomes following Vagus Nerve Sacrifice for Vagal Schwannoma Resection.
[So] Source:Otolaryngol Head Neck Surg;156(2):329-333, 2017 Feb.
[Is] ISSN:1097-6817
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Objective To determine the impact of unilateral vagal sacrifice for vagal schwannoma on postoperative swallowing function. Study Design Case series, chart review. Setting Academic medical institution. Subjects and Methods Ten patients underwent vagus nerve sacrifice for vagal schwannoma resection. Archived pathology records dating from 1985 through 2012 at our institution were retrospectively queried for cases of vagal schwannoma with vagus nerve sacrifice. Medical records were abstracted for demographic and disease information as well as cranial nerve and swallowing function. Preoperative and postoperative cranial nerve function, subjective and objective measures of swallowing function, Functional Oral Intake Scale (FOIS) level, and need for vocal fold medialization were variables collected. Data were analyzed with summary statistics. Results The patients who underwent vagal sacrifice for vagal schwannoma at our institution had a mean age of 42.3 years (median, 44 years; range, 15-63 years) and follow-up of 35.6 months (median, 9 months; range, 1-115 months). Most presented with no preoperative cranial nerve deficit or difficulty swallowing. Immediately postoperatively, 90% had a vagus nerve deficit, but 50% had no subjective difficulty swallowing, and 70% had a FOIS level of 7 at postoperative hospital discharge. Within 1 month after surgery, 70% had normal swallowing function according to a modified barium swallow study. A full diet was tolerated by mouth within an average of 2.7 days (median, 2 days; range, 1-6 days) after surgery in this cohort. Seventy percent required vocal fold medialization postoperatively for incomplete glottic closure. Conclusion Vagal nerve sacrifice during resection of vagal schwannoma can be performed with normal postoperative swallowing function.
[Mh] Termos MeSH primário: Neoplasias dos Nervos Cranianos/cirurgia
Deglutição/fisiologia
Neurilemoma/cirurgia
Nervo Vago/cirurgia
[Mh] Termos MeSH secundário: Adolescente
Adulto
Feminino
Seres Humanos
Masculino
Meia-Idade
Resultado do Tratamento
Prega Vocal/cirurgia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1707
[Cu] Atualização por classe:170724
[Lr] Data última revisão:
170724
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161201
[St] Status:MEDLINE
[do] DOI:10.1177/0194599816678210



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