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  1 / 1499 MEDLINE  
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[PMID]:29232394
[Au] Autor:Trinkaus E; Wu XJ
[Ad] Endereço:Department of Anthropology, Washington University, Saint Louis, MO, United States of America.
[Ti] Título:External auditory exostoses in the Xuchang and Xujiayao human remains: Patterns and implications among eastern Eurasian Middle and Late Pleistocene crania.
[So] Source:PLoS One;12(12):e0189390, 2017.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:In the context of Middle and Late Pleistocene eastern Eurasian human crania, the external auditory exostoses (EAE) of the late archaic Xuchang 1 and 2 and the Xujiayao 15 early Late Pleistocene human temporal bones are described. Xujiayao 15 has small EAE (Grade 1), Xuchang 1 presents bilateral medium EAE (Grade 2), and Xuchang 2 exhibits bilaterally large EAE (Grade 3), especially on the right side. These cranial remains join the other eastern Eurasian later Pleistocene humans in providing frequencies of 61% (N = 18) and 58% (N = 12) respectively for archaic and early modern human samples. These values are near the upper limits of recent human frequencies, and they imply frequent aquatic exposure among these Pleistocene humans. In addition, the medial extents of the Xuchang 1 and 2 EAE would have impinged on their tympanic membranes, and the large EAE of Xuchang 2 would have resulted in cerumen impaction. Both effects would have produced conductive hearing loss, a serious impairment in a Pleistocene foraging context.
[Mh] Termos MeSH primário: Exostose/patologia
Fósseis
Crânio/anatomia & histologia
[Mh] Termos MeSH secundário: Ásia
Europa (Continente)
História Antiga
Seres Humanos
[Pt] Tipo de publicação:HISTORICAL ARTICLE; JOURNAL ARTICLE
[Em] Mês de entrada:1801
[Cu] Atualização por classe:180104
[Lr] Data última revisão:
180104
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171213
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0189390


  2 / 1499 MEDLINE  
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[PMID]:29053746
[Au] Autor:Trinkaus E; Villotte S
[Ad] Endereço:Department of Anthropology, Washington University, Saint Louis, Missouri, United States of America.
[Ti] Título:External auditory exostoses and hearing loss in the Shanidar 1 Neandertal.
[So] Source:PLoS One;12(10):e0186684, 2017.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:The Late Pleistocene Shanidar 1 older adult male Neandertal is known for the crushing fracture of his left orbit with a probable reduction in vision, the loss of his right forearm and hand, and evidence of an abnormal gait, as well as probable diffuse idiopathic skeletal hyperostosis. He also exhibits advanced external auditory exostoses in his left auditory meatus and larger ones with complete bridging across the porus in the right meatus (both Grade 3). These growths indicate at least unilateral conductive hearing (CHL) loss, a serious sensory deprivation for a Pleistocene hunter-gatherer. This condition joins the meatal atresia of the Middle Pleistocene Atapuerca-SH Cr.4 in providing evidence of survival with conductive hearing loss (and hence serious sensory deprivation) among these Pleistocene humans. The presence of CHL in these fossils thereby reinforces the paleobiological and archeological evidence for supporting social matrices among these Pleistocene foraging peoples.
[Mh] Termos MeSH primário: Orelha Externa
Exostose
Fósseis
Perda Auditiva Condutiva
Hominidae
Homem de Neandertal
[Mh] Termos MeSH secundário: Animais
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1711
[Cu] Atualização por classe:171113
[Lr] Data última revisão:
171113
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171021
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0186684


  3 / 1499 MEDLINE  
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[PMID]:28641322
[Au] Autor:Livingstone DM; Smith KA; Lange B
[Ad] Endereço:Division of Otolaryngology - Head and Neck Surgery, Department of Surgery, University of Calgary, 7th floor, 4448 Front Street SE, Calgary, Alberta, Canada, T3M 1M4, dmliving@ucalgary.ca.
[Ti] Título:Scuba diving and otology: a systematic review with recommendations on diagnosis, treatment and post-operative care.
[So] Source:Diving Hyperb Med;47(2):97-109, 2017 Jun.
[Is] ISSN:1833-3516
[Cp] País de publicação:Australia
[La] Idioma:eng
[Ab] Resumo:Scuba diving is a popular recreational and professional activity with inherent risks. Complications related to barotrauma and decompression illness can pose significant morbidity to a diver's hearing and balance systems. The majority of dive-related injuries affect the head and neck, particularly the outer, middle and inner ear. Given the high incidence of otologic complications from diving, an evidence-based approach to the diagnosis and treatment of otic pathology is a necessity. We performed a systematic and comprehensive literature review including the pathophysiology, diagnosis, and treatment of otologic pathology related to diving. This included inner, middle, and outer ear anatomic subsites, as well as facial nerve complications, mal de debarquement syndrome, sea sickness and fitness to dive recommendations following otologic surgery. Sixty-two papers on diving and otologic pathology were included in the final analysis. We created a set of succinct evidence-based recommendations on each topic that should inform clinical decisions by otolaryngologists, dive medicine specialists and primary care providers when faced with diving-related patient pathology.
[Mh] Termos MeSH primário: Barotrauma
Fenômenos Biofísicos
Doença da Descompressão
Mergulho/lesões
Otopatias
[Mh] Termos MeSH secundário: Barotrauma/diagnóstico
Barotrauma/etiologia
Barotrauma/terapia
Doença da Descompressão/diagnóstico
Doença da Descompressão/etiologia
Doença da Descompressão/terapia
Mergulho/efeitos adversos
Otopatias/diagnóstico
Otopatias/etiologia
Otopatias/terapia
Orelha Interna
Orelha Média
Exostose/diagnóstico
Exostose/terapia
Seres Humanos
Otite Externa/etiologia
Otite Externa/terapia
Equilíbrio Postural
Transtornos das Sensações/etiologia
Transtornos das Sensações/terapia
Vertigem/etiologia
Vertigem/terapia
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Em] Mês de entrada:1708
[Cu] Atualização por classe:170808
[Lr] Data última revisão:
170808
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170623
[St] Status:MEDLINE


  4 / 1499 MEDLINE  
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[PMID]:28277770
[Au] Autor:Kim SH
[Ad] Endereço:Assistant Professor, Department of Otorhinolaryngology-Head and Neck Surgery, Jeju National University School of Medicine, Jeju, 63241, Republic of Korea.
[Ti] Título:Exostoses of the external auditory canals.
[So] Source:Br J Hosp Med (Lond);78(3):174, 2017 Mar 02.
[Is] ISSN:1750-8460
[Cp] País de publicação:England
[La] Idioma:eng
[Mh] Termos MeSH primário: Temperatura Baixa
Mergulho
Meato Acústico Externo/diagnóstico por imagem
Otopatias/diagnóstico por imagem
Exostose/diagnóstico por imagem
Exposição Ocupacional
[Mh] Termos MeSH secundário: Meato Acústico Externo/cirurgia
Otopatias/cirurgia
Exostose/cirurgia
Feminino
Seres Humanos
Meia-Idade
Fatores de Risco
Tomografia Computadorizada por Raios X
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Em] Mês de entrada:1706
[Cu] Atualização por classe:170615
[Lr] Data última revisão:
170615
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170310
[St] Status:MEDLINE
[do] DOI:10.12968/hmed.2017.78.3.174a


  5 / 1499 MEDLINE  
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[PMID]:28142170
[Ti] Título:Knochentumoren: Metastase oder Enostose?.
[So] Source:Rofo;189(2):112-113, 2017 Feb.
[Is] ISSN:1438-9010
[Cp] País de publicação:Germany
[La] Idioma:ger
[Mh] Termos MeSH primário: Neoplasias Ósseas/diagnóstico por imagem
Neoplasias Ósseas/secundário
Exostose/diagnóstico por imagem
Tomografia Computadorizada Multidetectores/métodos
Intensificação de Imagem Radiográfica/métodos
Interpretação de Imagem Radiográfica Assistida por Computador/métodos
[Mh] Termos MeSH secundário: Diagnóstico Diferencial
Feminino
Seres Humanos
Masculino
Osteoblastoma/diagnóstico por imagem
Reprodutibilidade dos Testes
Sensibilidade e Especificidade
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1703
[Cu] Atualização por classe:170817
[Lr] Data última revisão:
170817
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170201
[St] Status:MEDLINE
[do] DOI:10.1055/s-0042-122074


  6 / 1499 MEDLINE  
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[PMID]:27879421
[Au] Autor:Dou XW; Park W; Lee S; Zhang QZ; Carrasco LR; Le AD
[Ad] Endereço:1 Department of Oral and Maxillofacial Surgery and Pharmacology, University of Pennsylvania School of Dental Medicine, Philadelphia, PA, USA.
[Ti] Título:Loss of Notch3 Signaling Enhances Osteogenesis of Mesenchymal Stem Cells from Mandibular Torus.
[So] Source:J Dent Res;96(3):347-354, 2017 Mar.
[Is] ISSN:1544-0591
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Mandibular torus (MT) is a common intraoral osseous outgrowth located on the lingual surface of the mandible. Histologic features include hyperplastic bone consisting of mature cortical and trabecular bone. Some theories on the etiology of MT have been postulated, such as genetic factors, masticatory hyperfunction, trauma, and continued growth, but the underlying mechanism remains largely unknown. In this study, we investigated the potential role of mesenchymal stem cells (MSCs) derived from human MT in the pathogenesis of bone outgrowth. We demonstrated that MT harbored a distinct subpopulation of MSCs, with enhanced osteogenic and decreased adipogenic differentiation capacities, as compared with their counterparts from normal jaw bone. The increased osteogenic differentiation of mandibular torus MSCs was associated with the suppression of Notch3 signaling and its downstream target genes, Jag1 and Hey1, and a reciprocal increase in the transcriptional activation of ATF4 and NFATc1 genes. Targeted knockdown of Notch3 expression by transient siRNA transfection promoted the expression of osteogenic transcription factors in normal jaw bone MSCs. Our data suggest that the loss of Notch3 signaling may contribute partly to bone outgrowth in MT, as mediated by enhanced MSC-driven osteogenic differentiation in the jaw bone.
[Mh] Termos MeSH primário: Exostose/patologia
Mandíbula/anormalidades
Células Mesenquimais Estromais/patologia
Osteogênese/fisiologia
Receptor Notch3/metabolismo
[Mh] Termos MeSH secundário: Idoso
Western Blotting
Diferenciação Celular
Feminino
Seres Humanos
Masculino
Meia-Idade
RNA Interferente Pequeno
Reação em Cadeia da Polimerase em Tempo Real
Transdução de Sinais
Transfecção
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (NOTCH3 protein, human); 0 (RNA, Small Interfering); 0 (Receptor, Notch3)
[Em] Mês de entrada:1705
[Cu] Atualização por classe:170531
[Lr] Data última revisão:
170531
[Sb] Subgrupo de revista:D; IM
[Da] Data de entrada para processamento:161124
[St] Status:MEDLINE
[do] DOI:10.1177/0022034516680349


  7 / 1499 MEDLINE  
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[PMID]:27834109
[Au] Autor:Castro M; Goycoolea M; Silva-Pinto V
[Ad] Endereço:a Department of Morphology, School of Medicine , Clínica-Alemana-Universidad del Desarrollo , Santiago , Chile.
[Ti] Título:External ear canal exostosis and otitis media in temporal bones of prehistoric and historic chilean populations. A paleopathological and paleoepidemiological study.
[So] Source:Acta Otolaryngol;137(4):365-369, 2017 Apr.
[Is] ISSN:1651-2251
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:CONCLUSIONS: External ear canal exostosis is more prevalent in northern coastal groups than in the highlands, suggesting that ocean activities facilitate the appearance of exostosis. However, southern coastal groups exposed to colder ocean water have a lesser incidence of exostosis, possibly due to less duration of exposure. There was a high incidence of otitis media in all groups of native population in Chile. One coastal group had a higher incidence, presumably due to racial factors. BACKGROUND: This is a paleopathological and paleoepidemiological study in temporal bones which assesses external ear canal exostosis and otitis media in prehistoric and historic native populations in Chile. MATERIALS AND METHODS: A total of 460 temporal bones were evaluated for exostosis (ex) and 542 temporal bones were evaluated for otitis media (om). The study involved four groups: (1) Prehistoric Coastal (400-1000 AD) populations in Northern Chile (Pisagua-Tiwanaku) (22 temporal bones ex; 28 om); (2) Prehistoric Highland (400-1000 AD) populations in Northern Chile (292 temporal bones ex; 334 om); (3) Pisagua-Regional Developments (coastal) in Northern Chile (1000-1450 AD) (66 temporal bones ex; 82 om); and (4) Historic (1500-1800 AD) coastal populations in Southern Chile (80 temporal bones ex: 18 Chonos, 62 Fuegians. 98 om: 22 Chonos, 76 Fuegians). Skulls were evaluated visually and with an operating microscope. In addition, the otitis media group was evaluated with Temporal bone radiology - -lateral XRays-Schuller view - to assess pneumatization as evidence of previous middle ear disease. RESULTS: Prehistoric northern coastal groups had an incidence of exostosis of 15.91%, the northern highlands group 1.37%, and the southern coastal group 1.25%. There were changes suggestive of otitis media in: Pisagua/Tiwanaku 53.57%; Pisagua/Regional Developments 70.73%; Northern Highlands population 47.90%; Chonos 63.64%; and Fuegian tribes 64.47%.
[Mh] Termos MeSH primário: Exostose/patologia
Otite Média/patologia
Paleopatologia
Osso Temporal/patologia
[Mh] Termos MeSH secundário: Chile/epidemiologia
Exostose/epidemiologia
Seres Humanos
Otite Média/epidemiologia
[Pt] Tipo de publicação:COMPARATIVE STUDY; JOURNAL ARTICLE
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171016
[Lr] Data última revisão:
171016
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161112
[St] Status:MEDLINE
[do] DOI:10.1080/00016489.2016.1249949


  8 / 1499 MEDLINE  
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[PMID]:27795776
[Au] Autor:Traoré O; Chban K; Hode AF; Diarra Y; Salam S; Ouzidane L
[Ad] Endereço:Service de Radiologie Pédiatrique, Hôpital d'enfant CHU Ibn Rochd, Casablanca, Maroc.
[Ti] Título:[Interest of imaging in tumors benign bone in children].
[Ti] Título:Intérêt de l'imagerie dans les tumeurs osseuses bénignes chez l'enfant..
[So] Source:Pan Afr Med J;24:179, 2016.
[Is] ISSN:1937-8688
[Cp] País de publicação:Uganda
[La] Idioma:fre
[Ab] Resumo:Benign bone tumors are more common than malignant tumors in pediatrics. The exostosis (ostéchondrome) is the most common. The different imaging techniques are pivotal in the study of tumors including its standard radiography. The aim of this work is to highlight the interest in imaging the diagnostic management of bone benign tumors in children through a retrospective study of 169 patients. All patients were investigated by plain radiography, scanner supplement with multiplanar reconstruction before and after injection of PDC and / or MRI 1. 5 Tesla was performed according to the indication. The average age is 6 years with a slight male predominance. Clinically, the swelling is present in 35% of cases. The pain in 29% of cases. The most common location is the metaphyseal long bone on: Femur: 25% of cases, humerus: 17% of cases, Tibia: 21% of cases. Main Benign tumors are found exostosis (20. 12%), bone cyst (31. 95%) and osteoblastoma (16, 57%). The imagery is used to specify the topography and extension of the lesion in the bone provide arguments in favor of benign and sometimes in favor of the cause of the injury. The only standard radiograph often provides a diagnosis of certainty in some cases.
[Mh] Termos MeSH primário: Cistos Ósseos/diagnóstico por imagem
Neoplasias Ósseas/diagnóstico por imagem
Exostose/diagnóstico por imagem
Osteoblastoma/diagnóstico por imagem
[Mh] Termos MeSH secundário: Cistos Ósseos/epidemiologia
Neoplasias Ósseas/patologia
Criança
Exostose/epidemiologia
Feminino
Seres Humanos
Imagem por Ressonância Magnética
Masculino
Osteoblastoma/epidemiologia
Osteocondroma/diagnóstico por imagem
Osteocondroma/epidemiologia
Estudos Retrospectivos
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1703
[Cu] Atualização por classe:170313
[Lr] Data última revisão:
170313
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161101
[St] Status:MEDLINE


  9 / 1499 MEDLINE  
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[PMID]:27755370
[Au] Autor:Grinblat G; Prasad SC; Piras G; He J; Taibah A; Russo A; Sanna M
[Ad] Endereço:*Department of Otology & Skull Base Surgery, Gruppo Otologico, Piacenza, Rome, Italy†Department of Otorhinolaryngology, Hillel Yaffe Medical Center, Hadera, Israel‡Department of Otorhinolaryngology, Shanghai First People's Hospital, Shanghai Jiao Tong University, Shanghai, China.
[Ti] Título:Outcomes of Drill Canalplasty in Exostoses and Osteoma: Analysis of 256 Cases and Literature Review.
[So] Source:Otol Neurotol;37(10):1565-1572, 2016 Dec.
[Is] ISSN:1537-4505
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:OBJECTIVE: 1) To describe the surgical technique of drill canaplasty for exostosis and osteoma and to evaluate our results. 2) To propose a new grading system for external auditory canal stenosis (EACS). 3) To review the recent literature. STUDY DESIGN: A retrospective review. SETTING: Quarternary referral center for Otology & Skull Base surgery. SUBJECTS AND METHODS: Two hundred seventeen patients (256 ears) with exostosis or osteoma were included in the study. Surgical and audiological parameters were evaluated. RESULTS: Mean age was 51.5 (±13.41) years. One hundred sixty nine cases were men and 48 women. Two hundred forty three (95%) cases were exostosis and 13 (5%) were osteomas. According to the proposed grading system, 81% ears had severe or complete stenosis. Seventy eight (30.5%) ears had a concurrent diagnosis of otosclerosis. Retroauricular approach was used in 245 (95.7%). Intraoperative complications included tympanic membrane (TM) perforation seen in four (2%) and mastoid cell exposure in two (1%). Postoperative stenosis/prolonged healing was seen in 11 (4%) patients and required revision in seven cases. Audiologic analysis available for 153 ears-showed the mean change in air-bone gaps (ABG) of 2.18 dB, pure tone averages (PTA) bone conduction (BC) (0.5-4 kHz) of 0.3 dB. Mean healing rate was available for 246 (96.1%) patients and was found to be 6.35 (4-16) weeks. CONCLUSIONS: A systematically performed drill canalplasty via retroauricular approach, as described in this article, yields excellent postoperative outcomes as seen in our series. Notably, one-third of exostoses patients in this series, also suffered from otosclerosis. The proposed grading system for EACS enables the surgeon to objectively stage the disease.
[Mh] Termos MeSH primário: Neoplasias Ósseas/cirurgia
Exostose/cirurgia
Osteoma/cirurgia
Procedimentos Cirúrgicos Otológicos/métodos
[Mh] Termos MeSH secundário: Adolescente
Adulto
Idoso
Idoso de 80 Anos ou mais
Exostose/complicações
Feminino
Seres Humanos
Masculino
Processo Mastoide/cirurgia
Meia-Idade
Procedimentos Cirúrgicos Otológicos/efeitos adversos
Otosclerose/complicações
Otosclerose/cirurgia
Complicações Pós-Operatórias/etiologia
Estudos Retrospectivos
Perfuração da Membrana Timpânica/etiologia
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170908
[Lr] Data última revisão:
170908
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161019
[St] Status:MEDLINE


  10 / 1499 MEDLINE  
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[PMID]:27622256
[Au] Autor:Russell JD; Nance K; Nunley JR; Maher IA
[Ad] Endereço:Department of Dermatology, Virginia Commonwealth University, Richmond, USA.
[Ti] Título:Subungual exostosis.
[So] Source:Cutis;98(2):128-9, 2016 Aug.
[Is] ISSN:2326-6929
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Subungual exostosis is an uncommon bony tumor of the distal phalanx most often seen on the hallux. Although this lesion is completely benign, it must be distinguished from a number of other subungual tumors, both benign and malignant. Radiography of the digit is a noninvasive test that should be part of the initial workup whenever subungual exostosis is in the differential diagnosis. Once identified, surgical removal of the exostosis generally is both effective and well tolerated. We present a case of subungual exostosis that was discovered incidentally during a full-body skin examination. We also review the pertinent clinical and histopathologic findings, diagnosis, and treatment of this entity.
[Mh] Termos MeSH primário: Neoplasias Ósseas/diagnóstico
Exostose/diagnóstico
Hálux
Doenças da Unha/diagnóstico
[Mh] Termos MeSH secundário: Adulto
Neoplasias Ósseas/patologia
Exostose/patologia
Seres Humanos
Masculino
Doenças da Unha/patologia
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Em] Mês de entrada:1704
[Cu] Atualização por classe:170425
[Lr] Data última revisão:
170425
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160914
[St] Status:MEDLINE



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