Base de dados : MEDLINE
Pesquisa : C05.116.900 [Categoria DeCS]
Referências encontradas : 17098 [refinar]
Mostrando: 1 .. 10   no formato [Detalhado]

página 1 de 1710 ir para página                         

  1 / 17098 MEDLINE  
              next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:29505514
[Au] Autor:Lin YP; Li YJ; Chen BL; Guo YH
[Ad] Endereço:Guangdong Provincial Hospital of Chinese Medicine, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, China.
[Ti] Título:Lumbar laminotomy and replantation for the treatment of adult spinal epidermoid cyst: A case report.
[So] Source:Medicine (Baltimore);97(1):e9334, 2018 Jan.
[Is] ISSN:1536-5964
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:RATIONALE: Adult spinal epidermoid cyst (SEC) is a rare tumor. Lumbar laminectomy and tumor removal was a routine surgical procedure for adult spinal epidermoid cyst according to the literature, but postoperative lumbar instability and intractable low back pain may occur. In this study, we presented a brief report of an adult lumbar epidermoid cyst and introduced another surgical approach. PATIENT CONCERNS: This 28-year-old woman has been complaining of the severe right buttock pain and right thigh radiating pain for half a year. She had been diagnosed as sacroiliitis, spinal arthritis, and lumbar disc herniation at 3 different hospitals before coming to our hospital. And she received a variety of conservative treatments, including non-steroidal anti-inflammatory drugs, aspirin, acetaminophen, glucocorticoids, acupuncture, physical therapy, and so on. However, her pain did not diminish at all. Finally, we find a space-occupying lesion in her lumbar magnetic resonance images (MRI). The lesion was slightly low, equal, and uneven equal-low signals on T1WI. T2WI showed slightly higher, equal, and uneven equal-high signals. And a thin-rim enhancement was observed on Gd-DTPA-enhanced MRI. DIAGNOSES: Adult spinal epidermoid cyst. INTERVENTIONS: The patient underwent a surgery of lumbar laminectomy, tumor excision, and spinous process-vertebral plate in situ replantation. OUTCOMES: Postoperative pathology prompted that the tumor was cystoid. The patient's symptoms were completely removed 1 week after surgery. Three-month postoperative MRI confirmed that the spinal epidermoid cyst had been completely removed and three-dimensional CT prompted lumbar lamina in situ. Bony fusion occurred at 6 months after the surgery. LESSONS: Lumbar laminotomy and replantation provides an ideal option to treat adult spinal epidermoid cyst because it can completely remove the cyst and simultaneously reduce the risk of iatrogenic lumbar instability.
[Mh] Termos MeSH primário: Cisto Epidérmico/cirurgia
Laminectomia/métodos
Vértebras Lombares/cirurgia
Reimplante
Doenças da Coluna Vertebral/cirurgia
[Mh] Termos MeSH secundário: Adulto
Cisto Epidérmico/diagnóstico por imagem
Feminino
Seres Humanos
Vértebras Lombares/diagnóstico por imagem
Doenças da Coluna Vertebral/diagnóstico por imagem
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Em] Mês de entrada:1803
[Cu] Atualização por classe:180309
[Lr] Data última revisão:
180309
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:180306
[St] Status:MEDLINE
[do] DOI:10.1097/MD.0000000000009334


  2 / 17098 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:29408878
[Au] Autor:Freundt-Revilla J; Heinrich F; Zoerner A; Gesell F; Beyerbach M; Shamir M; Oevermann A; Baumgärtner W; Tipold A
[Ad] Endereço:Department of Small Animal Medicine and Surgery, University of Veterinary Medicine Hannover, Hannover, Germany.
[Ti] Título:The endocannabinoid system in canine Steroid-Responsive Meningitis-Arteritis and Intraspinal Spirocercosis.
[So] Source:PLoS One;13(2):e0187197, 2018.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Endocannabinoids (ECs) are involved in immunomodulation, neuroprotection and control of inflammation in the central nervous system (CNS). Activation of cannabinoid type 2 receptors (CB2) is known to diminish the release of pro-inflammatory factors and enhance the secretion of anti-inflammatory cytokines. Furthermore, the endocannabinoid 2-arachidonoyl glycerol (2-AG) has been proved to induce the migration of eosinophils in a CB2 receptor-dependent manner in peripheral blood and activate neutrophils independent of CB activation in humans. The aim of the current study was to investigate the influence of the endocannabinoid system in two different CNS inflammatory diseases of the dog, i.e. Steroid-Responsive Meningitis-Arteritis (SRMA) and Intraspinal Spirocercosis (IS). The two main endocannabinoids, anandamide (AEA) and 2-AG, were quantified by mass spectrometry in CSF and serum samples of dogs affected with Steroid- Responsive Meningitis-Arteritis in the acute phase (SRMA A), SRMA under treatment with prednisolone (SRMA Tr), intraspinal Spirocercosis and healthy dogs. Moreover, expression of the CB2 receptor was evaluated in inflammatory lesions of SRMA and IS and compared to healthy controls using immunohistochemistry (IHC). Dogs with SRMA A showed significantly higher concentrations of total AG and AEA in serum in comparison to healthy controls and in CSF compared to SRMA Tr (p<0.05). Furthermore, dogs with IS displayed the highest ECs concentrations in CSF, being significantly higher than in CSF samples of dogs with SRMA A (p<0.05). CSF samples that demonstrated an eosinophilic pleocytosis had the highest levels of ECs, exceeding those with neutrophilic pleocytosis, suggesting that ECs have a major effect on migration of eosinophils in the CSF. Furthermore, CB2 receptor expression was found in glial cells in the spinal cord of healthy dogs, whereas in dogs with SRMA and IS, CB2 was strongly expressed not only in glial cells but also on the cellular surface of infiltrating leukocytes (i.e. neutrophils, eosinophils, lymphocytes, plasma cells, and macrophages) at lesion sites. The present study revealed an upregulated endocannabinoid system in dogs with inflammatory CNS diseases, highlighting the endocannabinoid system as a potential target for treatment of inflammatory CNS diseases.
[Mh] Termos MeSH primário: Arterite/veterinária
Doenças do Cão/fisiopatologia
Endocanabinoides/fisiologia
Meningite/veterinária
Doenças da Coluna Vertebral/veterinária
Infecções por Spirurida/veterinária
[Mh] Termos MeSH secundário: Animais
Arterite/sangue
Arterite/líquido cefalorraquidiano
Arterite/fisiopatologia
Cromatografia Líquida
Doenças do Cão/sangue
Doenças do Cão/líquido cefalorraquidiano
Cães
Endocanabinoides/sangue
Endocanabinoides/líquido cefalorraquidiano
Espectrometria de Massas
Meningite/sangue
Meningite/líquido cefalorraquidiano
Meningite/fisiopatologia
Doenças da Coluna Vertebral/sangue
Doenças da Coluna Vertebral/líquido cefalorraquidiano
Doenças da Coluna Vertebral/fisiopatologia
Infecções por Spirurida/sangue
Infecções por Spirurida/líquido cefalorraquidiano
Infecções por Spirurida/fisiopatologia
Espectrometria de Massas em Tandem
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (Endocannabinoids)
[Em] Mês de entrada:1803
[Cu] Atualização por classe:180309
[Lr] Data última revisão:
180309
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180207
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0187197


  3 / 17098 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:29390306
[Au] Autor:Yin R; Wang L; Zhang T; Zhao B
[Ad] Endereço:Department of Orthopedic.
[Ti] Título:Syphilis of the lumbar spine: A case report and review of the literature.
[So] Source:Medicine (Baltimore);96(50):e9098, 2017 Dec.
[Is] ISSN:1536-5964
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:RATIONALE: Tertiary syphilis can manifest as gummatous disease, but gumma of the spine has been extremely rarely reported. PATIENT CONCERNS: A 61-year-old male complained of worsening pain and numbness in both lower legs for four weeks. DIAGNOSES: Syphilis of the Lumbar Spine. INTERVENTIONS: Pedicle screw fixation (L3-S1) and posterior decompression of the vertebral canal at L4-5 were performed. OUTCOMES: The postoperative VAS score of both lower extremities decline to 2 from 7 at admission. Dorsal thumb extensor motor power (left/right) at day 7 postoperatively was 3/3 (versus admission: 1/1). Laboratory examinations showed normal white blood cell count (versus admission: 13.8 × 10/L; reference value: 4.00-10.00 × 10/L) and decline in C-reactive protein (20.35 mg/L versus admission: 77.43 mg/L; reference value: 0.00-10.00 mg/mL) and ESR (58 mm versus admission: 73 mm; reference value: 0-15 mm). LESSONS: Our case illustrates that although gummatous disease of the spine may be extremely rare, it should be considered in the differential diagnosis of tuberculosis or malignancy of the spine so as to avoid a wrong diagnosis and incorrect treatment.
[Mh] Termos MeSH primário: Vértebras Lombares
Doenças da Coluna Vertebral/diagnóstico
Sífilis/diagnóstico
[Mh] Termos MeSH secundário: Descompressão Cirúrgica
Diagnóstico Diferencial
Seres Humanos
Masculino
Meia-Idade
Procedimentos Neurocirúrgicos
Parafusos Pediculares
Doenças da Coluna Vertebral/cirurgia
Sífilis/cirurgia
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE; REVIEW
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180301
[Lr] Data última revisão:
180301
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:180203
[St] Status:MEDLINE
[do] DOI:10.1097/MD.0000000000009098


  4 / 17098 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:29390489
[Au] Autor:Li HK; Hao DJ; Yang JS; Huang DG; Yu CC; Zhang JN; Gao L; Li H; Qian B
[Ad] Endereço:Department of Spine Surgery, Honghui Hospital, Xi'an Jiaotong University, Xi'an, Shaanxi, China.
[Ti] Título:Percutaneous kyphoplasty versus posterior spinal fixation with vertebroplasty for treatment of Kümmell disease: A case-control study with minimal 2-year follow-up.
[So] Source:Medicine (Baltimore);96(51):e9287, 2017 Dec.
[Is] ISSN:1536-5964
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:This is a retrospective case-control study.The aim of this study was to compare the surgical results of percutaneous kyphoplasty (KP) and posterior spinal fixation with vertebroplasty (PSF+VP) for treatment of Kümmell disease (KD).KD is rare form of post-traumatic delayed avascular necrosis of the vertebral body. It is reported that KP is an effect measure for treatment of KD. Some studies have recommended posterior spinal fixation with vertebroplasty for KD.A total of 100 patients with KD who underwent spinal surgery at our hospital were enrolled from January 2008 to December 2013. The inclusion criteria were monosegment lesion without neurological deficit; the segments are restricted to T11-L2; conservative treatment is invalid. The exclusion criteria were metastatic spinal tumors, infection, primary bone tumor, and multiple myeloma; bisegments and multi-segments; patients with neurological symptoms; the defect of posterior wall of vertebral body; the occupying of vertebral canal. The symptomatic vertebrae were restricted to T11-L2. Patients who were followed-up for less than 2 years after surgery were excluded. Finally, there are 25 patients in the KP group and 21 in the PSF+VP group. There were no significant differences in patient age, disease duration, or the length of follow-up between the 2 groups.Operative time (43.2 ±â€Š21.8 vs 230.6 ±â€Š87.1 minutes) was significantly longer and bleeding volume (5.3 ±â€Š3.1 vs 215.0 ±â€Š170.2 mL) significantly greater in the PSF+VP group. No significant difference between the 2 groups was observed in Visual analog scale score (VAS) (1.3 ±â€Š0.9 vs 1.2 ±â€Š0.9), Oswestry disability index score (ODI) (27.2 ±â€Š9.0 vs 26.0 ±â€Š6.3), and Cobb angle (17.0 ±â€Š7.2 vs 16.5 ±â€Š2.8). KP resulted in a shorter operation time, less bleeding volume, and fewer postoperative complications than PSF+VP.This study shows that both treatments KP and PSF+VP for KD can be safe and effective for the patients with monosegment lesion and without neurological deficit. However, KP show the advantages in a shorter surgical duration, less blood loss, and fewer postoperative complications.
[Mh] Termos MeSH primário: Cifoplastia/métodos
Osteonecrose/diagnóstico por imagem
Osteonecrose/cirurgia
Doenças da Coluna Vertebral/diagnóstico por imagem
Doenças da Coluna Vertebral/cirurgia
[Mh] Termos MeSH secundário: Adulto
Idoso
Perda Sanguínea Cirúrgica
Estudos de Casos e Controles
Distribuição de Qui-Quadrado
Bases de Dados Factuais
Feminino
Seguimentos
Seres Humanos
Cifoplastia/efeitos adversos
Masculino
Meia-Idade
Duração da Cirurgia
Osteonecrose/fisiopatologia
Medição da Dor
Complicações Pós-Operatórias/epidemiologia
Complicações Pós-Operatórias/fisiopatologia
Estudos Retrospectivos
Índice de Gravidade de Doença
Doenças da Coluna Vertebral/fisiopatologia
Fatores de Tempo
Tomografia Computadorizada por Raios X/métodos
Resultado do Tratamento
Vertebroplastia/efeitos adversos
Vertebroplastia/métodos
[Pt] Tipo de publicação:COMPARATIVE STUDY; JOURNAL ARTICLE
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180214
[Lr] Data última revisão:
180214
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:180203
[St] Status:MEDLINE
[do] DOI:10.1097/MD.0000000000009287


  5 / 17098 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:29297647
[Au] Autor:Byvaltsev VA; Kalinin AA; Belykh EG; Stepanov IA
[Ti] Título:Simulation technologies in spinal surgery.
[So] Source:Vestn Ross Akad Med Nauk;71(4):297-303, 2016.
[Is] ISSN:0869-6047
[Cp] País de publicação:Russia (Federation)
[La] Idioma:eng
[Ab] Resumo:This review reflects the current state of simulation technologies in neurosurgery and, in particular, in spinal surgery. Currently, there are different types of simulations used in spine surgery including the biological, artificial and virtual models. Simulations help to facilitate an optimal study of the anatomy, understand the spatial relationships between organs and tissues, plan properly the surgical intervention, and gain tactile surgical skills. The implementation of simulation technologies in the educational process provides objective assessment of the initial level of training, improvement of the competence in trained professionals, as well as prevention of surgical errors in various clinical situations.
[Mh] Termos MeSH primário: Simulação por Computador
Procedimentos Neurocirúrgicos
Doenças da Coluna Vertebral/cirurgia
[Mh] Termos MeSH secundário: Competência Clínica
Seres Humanos
Procedimentos Neurocirúrgicos/educação
Procedimentos Neurocirúrgicos/métodos
Melhoria de Qualidade
Resultado do Tratamento
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180208
[Lr] Data última revisão:
180208
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180104
[St] Status:MEDLINE
[do] DOI:10.15690/vramn681


  6 / 17098 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:29206837
[Au] Autor:Courjon J; Lemaignen A; Ghout I; Therby A; Belmatoug N; Dinh A; Gras G; Bernard L; DTS (Duration of Treatment for Spondylodiscitis) study group
[Ad] Endereço:Department of Infectious Diseases, University Hospital of Nice, Hôpital Archet 1, Nice, France.
[Ti] Título:Pyogenic vertebral osteomyelitis of the elderly: Characteristics and outcomes.
[So] Source:PLoS One;12(12):e0188470, 2017.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: The incidence of pyogenic vertebral osteomyelitis (PVO) has increased over the past two decades. One possible cause of this increase is the aging of the population, which results in more comorbidities in high income countries. OBJECTIVE: To better characterize the clinical presentation and outcome of PVO in the elderly. DESIGN: We conducted a post-hoc analysis of a previously published trial that studied treatment duration in PVO and compared the presentation and outcomes according to age. PARTICIPANTS: Our analysis included 351 patients among whom 85 (24%) were 75-years-old or more. RESULTS: There were no significant differences in the socio-demographics of the patients. Neoplasia and chronic inflammatory diseases were more common in the older group: 34% vs. 19% (p = 0.021) and 9% versus 1% (p = 0.004), respectively. There were no significant differences in clinical and radiological presentations between the groups in terms of back pain (337/351, 97%), fever (182/351, 52%), PVO localization, neurological signs and epidural abscess. Associated infective endocarditis (IE) was more frequent in the older group (37% vs. 14%, p<0.001). Streptococci were more frequently involved in infections of older patients (29% vs. 14%, p = 0.003) in contrast to Staphylococcus aureus (31% vs. 45%, p = 0.03). Older patients displayed higher mortality rates at 1 year (21% vs. 3%, p<0.001) and more adverse events related to cardiorespiratory failure (10.6% vs. 3.8%, p = 0.025), but had similar quality of life among the survivors. CONCLUSION: During PVO, the clinical and radiological findings are similar in older patients. Global mortality rates are higher in older patients compared to younger patients, which could be explained by the increased frequency of neoplasia at diagnosis and higher prevalence of associated IE in the elderly.
[Mh] Termos MeSH primário: Osteomielite/patologia
Doenças da Coluna Vertebral/patologia
Infecções Estafilocócicas/patologia
Staphylococcus aureus/isolamento & purificação
[Mh] Termos MeSH secundário: Idoso
Idoso de 80 Anos ou mais
Feminino
Seres Humanos
Masculino
Meia-Idade
Osteomielite/complicações
Osteomielite/tratamento farmacológico
Doenças da Coluna Vertebral/complicações
Infecções Estafilocócicas/tratamento farmacológico
Infecções Estafilocócicas/microbiologia
Resultado do Tratamento
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1712
[Cu] Atualização por classe:171229
[Lr] Data última revisão:
171229
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171206
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0188470


  7 / 17098 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:29245264
[Au] Autor:Li J; Qian M; Huang X; Zhao L; Yang X; Xiao J
[Ad] Endereço:aDepartment of Orthopedics Oncology, Changzheng HospitalbDepartment of Pathology, Changhai HospitalcNursing School, Second Military Medical University, Shanghai, China.
[Ti] Título:Repeated recurrent epidermoid cyst with atypical hyperplasia: A case report and literature review.
[So] Source:Medicine (Baltimore);96(49):e8950, 2017 Dec.
[Is] ISSN:1536-5964
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:RATIONALE: Epidermoid cysts are slow-growing, benign tumor which account for less than 1% of all intraspinal tumors and epidermoid cyst with Atypical Hyperplasia is very rare. Surgical resection is the standard treatment of the tumor, but recurrence is not uncommon after incomplete resection. Inappropriate treatment can lead to repeated recurrent. Here, we reported a case of repeated recurrent epidermoid cyst with atypical hyperplasia treated with radiotherapy after surgery. PRESENTING CONCERNS: A 40-year-old female presenting with intraspinal epidermoid cyst showed incomplete paraplegia in lower limbs. DIAGNOSIS: Back pain reappeared 19 months later after surgical treatment. The patient suffered marked weakness in both limbs, along with obvious muscle atrophy and sensation deficiency of warmth and pain in left lower limb. MRI demonstrated a cystic mass with solid content and peripheral strengthen in enhanced scan. INTERVENTIONS: Extended excision with intraoperative local chemotherapy and postoperative radiotherapy was performed and a dramatic reversal of symptoms was gained 4 weeks after surgery, with a total dose of 46 Gy. Postoperative pathological examination revealed epidermoid cyst with mild to moderate atypical hyperplasia. OUTCOMES: No acute side effects of the treatment were reported. Back pain obviously alleviated within 48 hours after surgery, while weakness and numbness of the lower limbs gradually improved and nearly disappeared in the 3-monthly follow-up visit. Until now, no recurrence is found during the 5-years follow-up. LESSONS: Our study highlights that incomplete excision has led to repeated recurrent epidermoid cyst, but its complete removal with adjuvant radiotherapy has achieved remission of symptoms. Atypical hyperplasia discovered by pathological examination reminds us the possibility of malignant transformation and ensures the necessity of adequate treatment.
[Mh] Termos MeSH primário: Cisto Epidérmico/diagnóstico
Cisto Epidérmico/terapia
Doenças da Coluna Vertebral/diagnóstico
Doenças da Coluna Vertebral/terapia
[Mh] Termos MeSH secundário: Adulto
Terapia Combinada
Cisto Epidérmico/patologia
Feminino
Seres Humanos
Hiperplasia
Debilidade Muscular
Recidiva
Doenças da Coluna Vertebral/patologia
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE; REVIEW
[Em] Mês de entrada:1712
[Cu] Atualização por classe:171225
[Lr] Data última revisão:
171225
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:171217
[St] Status:MEDLINE
[do] DOI:10.1097/MD.0000000000008950


  8 / 17098 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:29069048
[Au] Autor:Kong L; Tian W; Cao P; Wang H; Zhang B; Shen Y
[Ad] Endereço:Department of Orthopedics, The Third Hospital of Hebei Medical University, Shijiazhuang, Hebei, P.R. China.
[Ti] Título:Predictive factors associated with neck pain in patients with cervical disc degeneration: A cross-sectional study focusing on Modic changes.
[So] Source:Medicine (Baltimore);96(43):e8447, 2017 Oct.
[Is] ISSN:1536-5964
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:The predictive factors associated with neck pain remain unclear. We conducted a cross-sectional study to assess predictive factors, especially Modic changes (MCs), associated with the intensity and duration of neck pain in patients with cervical disc degenerative disease.We retrospectively reviewed patients in our hospital from January 2013 to December 2016. Severe neck pain (SNP) and persistent neck pain (PNP) were the 2 main outcomes, and were assessed based on the numerical rating scale (NRS). Basic data, and also imaging data, were collected and analyzed as potential predictive factors. Univariate analysis and multiple logistic regression analysis were performed to assess the predictive factors for neck pain.In all, 381 patients (193 males and 188 females) with cervical degenerative disease were included in our study. The number of patients with SNP and PNP were 94 (24.67%) and 109 (28.61%), respectively. The NRS of neck pain in patients with type 1 MCs was significantly higher than type 2 MCs (4.8 ±â€Š0.9 vs 3.9 ±â€Š1.1; P = .004). The multivariate logistic analysis showed that kyphosis curvature (odds ratio [OR] 1.082, 95% confidence interval [CI] 1.044-1.112), spondylolisthesis (OR 1.339, 95% CI 1.226-1.462), and annular tear (OR 1.188, 95% CI 1.021-1.382) were factors associated with SNP, whereas kyphosis curvature (OR 1.568, 95% CI 1.022-2.394), spondylolisthesis (OR 1.486, 95% CI 1.082-2.041), and MCs (OR 1.152, 95% CI 1.074-1.234) were associated with PNP.We concluded that kyphosis curvature, spondylolisthesis, and annular tear are associated with SNP, whereas kyphosis curvature, spondylolisthesis, and MCs are associated with PNP. This study supports the view that MCs can lead to a long duration of neck pain.
[Mh] Termos MeSH primário: Vértebras Cervicais
Degeneração do Disco Intervertebral/complicações
Cervicalgia/etiologia
[Mh] Termos MeSH secundário: Adulto
Fenômenos Biomecânicos
Estudos Transversais
Feminino
Seres Humanos
Cifose/complicações
Modelos Logísticos
Lordose/complicações
Masculino
Meia-Idade
Análise Multivariada
Medição da Dor
Estudos Retrospectivos
Fatores de Risco
Doenças da Coluna Vertebral/complicações
Espondilolistese/complicações
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1711
[Cu] Atualização por classe:171123
[Lr] Data última revisão:
171123
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:171026
[St] Status:MEDLINE
[do] DOI:10.1097/MD.0000000000008447


  9 / 17098 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:28976436
[Au] Autor:Reitmaier S; Graichen F; Shirazi-Adl A; Schmidt H
[Ad] Endereço:1Julius Wolff Institute, Charité-Universitätsmedizin Berlin, Berlin, Germany 2École Polytechnique, Montréal, Canada.
[Ti] Título:Separate the Sheep from the Goats: Use and Limitations of Large Animal Models in Intervertebral Disc Research.
[So] Source:J Bone Joint Surg Am;99(19):e102, 2017 Oct 04.
[Is] ISSN:1535-1386
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Approximately 5,168 large animals (pigs, sheep, goats, and cattle) were used for intervertebral disc research in identified studies published between 1985 and 2016. Most of the reviewed studies revealed a low scientific impact, a lack of sound justifications for the animal models, and a number of deficiencies in the documentation of the animal experimentation. The scientific community should take suitable measures to investigate the presumption that animal models have translational value in intervertebral disc research. Recommendations for future investigations are provided to improve the quality, validity, and usefulness of animal studies for intervertebral disc research. More in vivo studies are warranted to comprehensively evaluate the suitability of animal models in various applications and help place animal models as an integral, complementary part of intervertebral disc research.
[Mh] Termos MeSH primário: Disco Intervertebral/cirurgia
Modelos Animais
Pesquisa
Doenças da Coluna Vertebral/cirurgia
[Mh] Termos MeSH secundário: Experimentação Animal/ética
Animais
Bovinos
Cabras
Ovinos
Sus scrofa
Pesquisa Médica Translacional
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171013
[Lr] Data última revisão:
171013
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:171005
[St] Status:MEDLINE
[do] DOI:10.2106/JBJS.17.00172


  10 / 17098 MEDLINE  
              first record previous record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:28963158
[Au] Autor:Patrick S; McDowell A; Lee A; Frau A; Martin U; Gardner E; McLorinan G; Eames N
[Ad] Endereço:Centre for Experimental Medicine, School of Medicine Dentistry and Biomedical Sciences, Queen's University of Belfast, 97 Lisburn Road, Belfast, BT9 7BL, UK.
[Ti] Título:Antisepsis of the skin before spinal surgery with povidone iodine-alcohol followed by chlorhexidine gluconate-alcohol povidone iodine-alcohol applied twice for the prevention of contamination of the wound by bacteria: a randomised controlled trial.
[So] Source:Bone Joint J;99-B(10):1354-1365, 2017 Oct.
[Is] ISSN:2049-4408
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:AIMS: The aim of this study was to determine whether the sequential application of povidone iodine-alcohol (PVI) followed by chlorhexidine gluconate-alcohol (CHG) would reduce surgical wound contamination to a greater extent than PVI applied twice in patients undergoing spinal surgery. PATIENTS AND METHODS: A single-centre, interventional, two arm, parallel group randomised controlled trial was undertaken, involving 407 patients who underwent elective spinal surgery. For 203 patients, the skin was disinfected before surgery using PVI (10% [w/w (1% w/w available iodine)] in 95% industrial denatured alcohol, povidone iodine; Videne Alcoholic Tincture) twice, and for 204 patients using PVI once followed by CHG (2% [w/v] chlorhexidine gluconate in 70% [v/v] isopropyl alcohol; Chloraprep with tint). The primary outcome measure was contamination of the wound determined by aerobic and anaerobic bacterial growth from samples taken after disinfection. RESULTS: The detection of viable bacteria in any one of the samples taken after disinfection (culture-positive) was significantly lower in the group treated with both PVI and CHG than in the group treated with PVI alone (59 (29.1%) 85 (41.7%), p = 0.009; odds ratio 0.574; 95% confidence interval, 0.380 to 0.866). CONCLUSIONS: Antisepsis of the skin with the sequential application of PVI and CHG more effectively reduces the contamination of a surgical wound than PVI alone. Cite this article: 2017;99-B:1354-65.
[Mh] Termos MeSH primário: Antissepsia/métodos
Clorexidina/análogos & derivados
Etanol/administração & dosagem
Procedimentos Neurocirúrgicos
Povidona-Iodo/administração & dosagem
Cuidados Pré-Operatórios/métodos
Infecção da Ferida Cirúrgica/prevenção & controle
[Mh] Termos MeSH secundário: Administração Tópica
Anti-Infecciosos Locais/administração & dosagem
Clorexidina/administração & dosagem
Esquema de Medicação
Combinação de Medicamentos
Feminino
Seres Humanos
Masculino
Doenças da Coluna Vertebral/cirurgia
[Pt] Tipo de publicação:JOURNAL ARTICLE; RANDOMIZED CONTROLLED TRIAL
[Nm] Nome de substância:
0 (Anti-Infective Agents, Local); 0 (Drug Combinations); 3K9958V90M (Ethanol); 85H0HZU99M (Povidone-Iodine); MOR84MUD8E (chlorhexidine gluconate); R4KO0DY52L (Chlorhexidine)
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171116
[Lr] Data última revisão:
171116
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:171001
[St] Status:MEDLINE
[do] DOI:10.1302/0301-620X.99B10.BJJ-2017-0291.R1



página 1 de 1710 ir para página                         
   


Refinar a pesquisa
  Base de dados : MEDLINE Formulário avançado   

    Pesquisar no campo  
1  
2
3
 
           



Search engine: iAH v2.6 powered by WWWISIS

BIREME/OPAS/OMS - Centro Latino-Americano e do Caribe de Informação em Ciências da Saúde