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[PMID]:28460079
[Au] Autor:Ehrmann Feldman D; Vinet É; Sylvestre MP; Hazel B; Duffy C; Bérard A; Meshefedjian G; Bernatsky S
[Ad] Endereço:School of Rehabilitation, Faculty of Medicine.
[Ti] Título:Postpartum complications in new mothers with juvenile idiopathic arthritis: a population-based cohort study.
[So] Source:Rheumatology (Oxford);56(8):1378-1385, 2017 Aug 01.
[Is] ISSN:1462-0332
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Objective: The aim was to evaluate the prevalence of postpartum complications, including depression, in new mothers who had juvenile idiopathic arthritis (JIA) and to assess whether these differ from mothers who never had JIA. Methods: Our cohort study used data from physician billing and hospitalizations covering Quebec, Canada. We identified females with JIA with a first-time birth between 1 January 1983 and 31 December 2010 and assembled a control cohort of first-time mothers without JIA from the same administrative data, matching 4:1 for date of first birth, maternal age and area of residence. We compared the following postpartum complications: major puerperal infection, anaesthetic complications, postpartum haemorrhage, thromboembolism, obstetrical trauma, complications of obstetrical surgical wounds and maternal depression in the first year after delivery, in the JIA vs non-JIA groups, using bivariate analysis and multiple logistic regression. Results: The mean age at delivery was 24.7 years in the JIA group (n = 1681) and 25.0 years for the non-JIA group (n = 6724). Mothers with JIA were more likely to experience complications attributable to anaesthetic [adjusted risk ratio (aRR) 2.17, 95% CI; 1.05, 4.48], postpartum haemorrhage (aRR = 2.75, 95% CI: 2.42, 3.11) and thromboembolism (aRR = 5.27, 95% CI: 1.83, 15.17) but were at lower risk for obstetrical trauma (aRR = 0.78, 95% CI: 0.64, 0.95) or newly to develop depression in the first year postpartum (aRR = 0.52, 95% CI: 0.40, 0.68). Conclusion: Mothers with JIA appear to be at higher risk for complications attributable to anaesthesia, postpartum haemorrhage and thromboembolism. Prevention strategies for postpartum haemorrhage and thromboembolism may be especially important in this population.
[Mh] Termos MeSH primário: Artrite Juvenil/complicações
Complicações do Trabalho de Parto/etiologia
Transtornos Puerperais/etiologia
[Mh] Termos MeSH secundário: Adulto
Anestesia/efeitos adversos
Estudos de Casos e Controles
Estudos de Coortes
Depressão Pós-Parto/etiologia
Feminino
Seres Humanos
Modelos Logísticos
Hemorragia Pós-Parto/etiologia
Período Pós-Parto
Gravidez
Quebeque
Fatores de Risco
Tromboembolia/etiologia
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1709
[Cu] Atualização por classe:180308
[Lr] Data última revisão:
180308
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:170502
[St] Status:MEDLINE
[do] DOI:10.1093/rheumatology/kex168


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[PMID]:28464909
[Au] Autor:Gmuca S; Xiao R; Brandon TG; Pagnini I; Wright TB; Beukelman T; Morgan EM; Weiss PF
[Ad] Endereço:Division of Rheumatology, Department of Pediatrics, The Children's Hospital of Philadelphia, Philadelphia, PA, USA.
[Ti] Título:Multicenter inception cohort of enthesitis-related arthritis: variation in disease characteristics and treatment approaches.
[So] Source:Arthritis Res Ther;19(1):84, 2017 May 02.
[Is] ISSN:1478-6362
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Enthesitis-related arthritis (ERA) is a specific subtype of juvenile idiopathic arthritis (JIA) defined according to the International League of Associations for Rheumatology (ILAR) criteria. We aimed to characterize the clinical features and treatment regimens in an inception cohort of children with ERA. METHODS: We performed a retrospective, cross-sectional, multicenter cohort study including subjects diagnosed with ERA between 1989 and 2012. Patients all fulfilled the ILAR criteria for ERA within 3 months of initial presentation to the rheumatology clinic. Differences in the prevalence of clinical criteria across study sites and by human leukocyte antigen (HLA)-B27 status were assessed using the Wilcoxon rank-sum or chi-square test, as appropriate. RESULTS: Two hundred thirty-four children met the inclusion criteria. Their median age at diagnosis was 11.6 years, and 59% were HLA-B27-positive. Sixty-nine percent had enthesitis and arthritis at the time of diagnosis. Seventy-eight percent had a pauciarticular onset. The prevalence of all ILAR criteria at diagnosis, except arthritis and acute anterior uveitis, differed significantly across sites (all p < 0.01). Medication use varied significantly across sites for children with peripheral arthritis (p < 0.001), but not for sacroiliitis or enthesitis only. Nonsteroidal anti-inflammatory drugs and disease-modifying antirheumatic drugs were the most commonly prescribed treatments, with anti-TNF agents primarily being initiation for sacroiliitis. HLA-B27 positivity was associated with male sex, higher active joint count, sacroiliitis, and higher disease activity at disease onset. CONCLUSIONS: The majority of children had a pauciarticular onset, and several statistically significant clinical differences based on HLA-B27 status were identified. The observed heterogeneity in clinical presentation across sites reflects either true differences in patient populations or differences in how the ILAR criteria are being applied.
[Mh] Termos MeSH primário: Anti-Inflamatórios não Esteroides/uso terapêutico
Antirreumáticos/uso terapêutico
Artrite Juvenil/diagnóstico
Artrite Juvenil/tratamento farmacológico
Internacionalidade
[Mh] Termos MeSH secundário: Adolescente
Artrite Juvenil/sangue
Criança
Estudos de Coortes
Estudos Transversais
Feminino
Antígeno HLA-B27/sangue
Seres Humanos
Masculino
Estudos Retrospectivos
Resultado do Tratamento
[Pt] Tipo de publicação:JOURNAL ARTICLE; MULTICENTER STUDY
[Nm] Nome de substância:
0 (Anti-Inflammatory Agents, Non-Steroidal); 0 (Antirheumatic Agents); 0 (HLA-B27 Antigen)
[Em] Mês de entrada:1803
[Cu] Atualização por classe:180302
[Lr] Data última revisão:
180302
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170504
[St] Status:MEDLINE
[do] DOI:10.1186/s13075-017-1297-x


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[PMID]:29407498
[Au] Autor:Stoustrup PB; Ahlefeldt-Laurvig-Lehn N; Kristensen KD; Arvidsson LZ; Twilt M; Cattaneo PM; Küseler A; Christensen AE; Herlin T; Pedersen TK
[Ad] Endereço:Section of Orthodontics, Aarhus University, Aarhus, Denmark. Electronic address: pstoustrup@odont.au.dk.
[Ti] Título:No association between types of unilateral mandibular condylar abnormalities and facial asymmetry in orthopedic-treated patients with juvenile idiopathic arthritis.
[So] Source:Am J Orthod Dentofacial Orthop;153(2):214-223, 2018 Feb.
[Is] ISSN:1097-6752
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:INTRODUCTION: Dentofacial asymmetries are often observed in patients with juvenile idiopathic arthritis (JIA) and temporomandibular joint (TMJ) involvements. The aim of this split-face study was to associate types of radiologic TMJ abnormalities with the degree of dentofacial asymmetry in patients with unilateral TMJ involvements assessed with cone-beam computed tomography. METHODS: Forty-seven JIA patients and 19 nonarthritic control subjects were included in the study. Normal condylar radiologic cone-beam computed tomography appearance in at least 1 TMJ was the inclusion criterion for all patients with JIA. The contralateral TMJ was thereafter scored as either "normal," "deformed," or "erosive," consistent with predefined criteria. Based on the bilateral radiologic TMJ appearances, 3 JIA groups were assigned: normal/normal, normal/deformed, and normal/erosive. The severity of the dentofacial asymmetry was compared between the JIA groups and control subjects. Dentofacial asymmetry was expressed as interside ratios and angular measurements. RESULTS: Eighty-seven percent of the JIA patients were being treated or had previously received treatment with a functional orthopedic appliance at the time of the cone-beam computed tomography. Significantly greater dentofacial asymmetries were observed in the 2 groups of JIA patients with unilateral condylar abnormalities (deformation or erosion) than in the other groups. A similar degree of dentofacial asymmetry was observed in JIA patients with bilateral normal TMJs and in the nonarthritic control group. CONCLUSIONS: JIA patients with unilateral condylar abnormalities (deformation or erosion) exhibited significantly more severe dentofacial asymmetries than did the JIA patients without condylar abnormalities and the control subjects. We found the same degree of dentofacial asymmetry when dividing patients with condylar abnormalities into deformation and erosion groups.
[Mh] Termos MeSH primário: Artrite Juvenil/complicações
Assimetria Facial/etiologia
Côndilo Mandibular/anormalidades
[Mh] Termos MeSH secundário: Adolescente
Estudos de Casos e Controles
Criança
Feminino
Seres Humanos
Masculino
Côndilo Mandibular/diagnóstico por imagem
Radiografia Dentária
Articulação Temporomandibular/anormalidades
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180213
[Lr] Data última revisão:
180213
[Sb] Subgrupo de revista:D; IM
[Da] Data de entrada para processamento:180207
[St] Status:MEDLINE


  4 / 9122 MEDLINE  
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[PMID]:29246341
[Au] Autor:Schenck S; Rosenbauer J; Niewerth M; Klotsche J; Minden K; Schwarz T; Foeldvari I; Horneff G; Weller-Heinemann F; Holl RW; Thon A
[Ad] Endereço:German Rheumatism Research Center Berlin, a Leibniz Institute, Berlin, Berlin, Germany. Electronic address: Sandra.Schenck@drfz.de.
[Ti] Título:Comorbidity of Type 1 Diabetes Mellitus in Patients with Juvenile Idiopathic Arthritis.
[So] Source:J Pediatr;192:196-203, 2018 Jan.
[Is] ISSN:1097-6833
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:OBJECTIVES: To determine the prevalence of type 1 diabetes mellitus (T1D) in patients with juvenile idiopathic arthritis (JIA) and to characterize patients having both. STUDY DESIGN: Diabetes comorbidity was recorded in the National Pediatric Rheumatologic Database since 2012. Data from the North Rhine-Westphalian diabetes registry served as the reference population for the prevalence of diabetes in the general population. The National Pediatric Rheumatologic Database data were indirectly standardized for age and sex for comparison with the general population. The diabetes prevalence ratio was calculated using the Poisson regression model. RESULTS: The analysis included 12 269 patients with JIA. A total of 58 patients had comorbid T1D, and the diabetes prevalence was 0.5%. The mean age was 11.6 years at the time of documentation, and the mean disease duration was 4.2 years. Compared with the general population, the prevalence of diabetes in patients with JIA was significantly increased (prevalence ratio 1.76 [95% CI 1.34; 2.28], P < .001). The onset of diabetes in patients with JIA was earlier than that reported in the reference data. Sixty-three percent of patients developed T1D before JIA. On average, diabetes onset was 56 months before the onset of JIA. Patients who first developed JIA developed T1D on average 40 months later. The majority of patients had not received disease-modifying antirheumatic drugs before diabetes onset. CONCLUSIONS: T1D occurs more frequently in patients with JIA than in the general population. The likelihood of T1D occurrence appears to be slightly higher before JIA manifestation and without disease-modifying antirheumatic drug therapy after JIA onset.
[Mh] Termos MeSH primário: Artrite Juvenil/epidemiologia
Diabetes Mellitus Tipo 1/epidemiologia
[Mh] Termos MeSH secundário: Adolescente
Idade de Início
Criança
Pré-Escolar
Comorbidade
Estudos Transversais
Bases de Dados Factuais
Feminino
Alemanha/epidemiologia
Seres Humanos
Masculino
Distribuição de Poisson
Prevalência
Sistema de Registros
Análise de Regressão
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1712
[Cu] Atualização por classe:171226
[Lr] Data última revisão:
171226
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:171217
[St] Status:MEDLINE


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[PMID]:29088453
[Au] Autor:Dimopoulou D; Trachana M; Pratsidou-Gertsi P; Sidiropoulos P; Kanakoudi-Tsakalidou F; Dimitroulas T; Garyfallos A
[Ad] Endereço:4th Academic Department of Internal Medicine, Aristotle University.
[Ti] Título:Predictors and long-term outcome in Greek adults with juvenile idiopathic arthritis: a 17-year continuous follow-up study.
[So] Source:Rheumatology (Oxford);56(11):1928-1938, 2017 Nov 01.
[Is] ISSN:1462-0332
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Objectives: To describe the disease characteristics, continuous course and long-term outcome and to evaluate predictors of outcome in JIA in Greece. Methods: We performed a retrospective cohort analysis of 17 years' prospective data on JIA. Outcome assessment included radiographic (modified Sharp-van der Heidje score), articular and extra-articular damage (Juvenile Arthritis Damage Index), functional ability (HAQ Disability Index), and the cumulative percentage time spent in a state of active disease and also in clinical remission off medication (CR) (according to Wallace's criteria). Results: One hundred and two (72 females) patients under regular follow-up were enrolled. The disease age of onset [mean (SD)] was 7.7 (4) years, the interval from onset to last visit was 17.2 (6.7) years and the patients' current age was 25 (5.9) years. At the last follow-up visit, 53 patients (52%) had disease activity, while 23.5% were in CR. The cumulative percentage time spent in a state of active disease and CR over the disease course was 52.6 and 17.8%, respectively. Polyarticular subtype of onset and longer disease activity during the first 5 years were independent predictors of worse outcome. Additional telephone-based interviews of 205 former JIA patients who had been lost to follow-up as adults were performed to extend the interpretation of our findings to a broader JIA population. Almost half (47.6%) of the total cohort of 307 patients were found to be in CR at the final evaluation and 69.7% had no disability. Conclusion: The available data indicate that JIA as a whole is a heterogeneous disease with significant variability in course and long-term outcome.
[Mh] Termos MeSH primário: Atividades Cotidianas
Artrite Juvenil/fisiopatologia
[Mh] Termos MeSH secundário: Adolescente
Adulto
Anticorpos Antinucleares/imunologia
Antirreumáticos/uso terapêutico
Artrite Juvenil/complicações
Artrite Juvenil/tratamento farmacológico
Artrite Juvenil/imunologia
Sedimentação Sanguínea
Proteína C-Reativa/imunologia
Estudos de Coortes
Progressão da Doença
Feminino
Seguimentos
Grécia
Seres Humanos
Masculino
Peptídeos Cíclicos/imunologia
Prognóstico
Indução de Remissão
Estudos Retrospectivos
Fatores de Tempo
Uveíte/etiologia
Uveíte/fisiopatologia
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Antibodies, Antinuclear); 0 (Antirheumatic Agents); 0 (Peptides, Cyclic); 0 (cyclic citrullinated peptide); 9007-41-4 (C-Reactive Protein)
[Em] Mês de entrada:1711
[Cu] Atualização por classe:171106
[Lr] Data última revisão:
171106
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:171101
[St] Status:MEDLINE
[do] DOI:10.1093/rheumatology/kex265


  6 / 9122 MEDLINE  
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[PMID]:28957547
[Au] Autor:Peeters JGC; de Graeff N; Lotz M; Albani S; de Roock S; van Loosdregt J
[Ad] Endereço:Center for Molecular Medicine.
[Ti] Título:Increased autophagy contributes to the inflammatory phenotype of juvenile idiopathic arthritis synovial fluid T cells.
[So] Source:Rheumatology (Oxford);56(10):1694-1699, 2017 Oct 01.
[Is] ISSN:1462-0332
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Objectives: JIA is an autoimmune disease involving disturbed T-cell homeostasis, marked by highly activated effector T cells. Autophagy, a lysosomal degradation pathway, is crucial for maintaining cellular homeostasis by regulating the survival, differentiation and function of a large variety of cells, including T cells. The aim of this study was to examine the rate of autophagy in JIA T cells and to investigate the effect of inhibition of autophagy on the inflammatory phenotype of JIA T cells. Methods: Autophagy-related gene expression was analysed in CD4+ T cells from the SF of JIA patients and healthy controls using RNA sequencing. Autophagy was measured by flow cytometry and western blot. The effect of inhibition of autophagy, using HCQ, on the cellular activation status was analysed using flow cytometry and multiplex immunoassay. Results: Autophagy was increased in T cells derived from the site of inflammation compared with cells from the peripheral blood of patients and healthy controls. This increase in autophagy was not induced by JIA SF, but is more likely to be the result of increased cellular activation. Inhibition of autophagy reduced proliferation, cytokine production and activation marker expression of JIA SF-derived CD4+ T cells. Conclusion: These data indicate that autophagy is increased in JIA SF-derived T cells and that targeting autophagy could be a promising therapeutic strategy to restore the disrupted T-cell homeostasis in JIA.
[Mh] Termos MeSH primário: Artrite Juvenil/imunologia
Autofagia/imunologia
Linfócitos T CD4-Positivos/fisiologia
Líquido Sinovial/citologia
[Mh] Termos MeSH secundário: Adolescente
Adulto
Idoso
Linfócitos T CD4-Positivos/imunologia
Estudos de Casos e Controles
Criança
Pré-Escolar
Feminino
Citometria de Fluxo
Seres Humanos
Masculino
Meia-Idade
Fenótipo
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171006
[Lr] Data última revisão:
171006
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:170929
[St] Status:MEDLINE
[do] DOI:10.1093/rheumatology/kex227


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[PMID]:28954874
[Au] Autor:Merlin E; Breton S; Fraitag S; Stéphan JL; Wouters C; Bodemer C; Bader-Meunier B
[Ad] Endereço:Inserm CIC 1405, Centre Hospitalier Universitaire de Clermont-Ferrand, Clermont-Ferrand, France.
[Ti] Título:Fibrous Arthropathy Associated With Morphea: A New Cause of Diffuse Acquired Joint Contractures.
[So] Source:Pediatrics;140(4), 2017 Oct.
[Is] ISSN:1098-4275
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Etiologies for childhood-onset diffuse joint contractures encompass a large group of inherited disorders and acquired diseases, in particular a subtype of juvenile idiopathic arthritis called "dry polyarthritis," dermatomyositis, and systemic sclerosis. We report on 2 boys, aged 5 and 8 years, who developed acquired symmetric painless joint contractures preceding the development of superficial plaques of morphea by 7 to 13 months. There was no other clinical involvement, biological inflammation, or autoantibodies. No urinary mucopolysaccharidosis was seen. In both patients, wrist MRI showed no joint effusion, no bone erosion, and no or mild synovial thickening with slight enhancement after gadolinium infusion. One patient underwent a synovial biopsy, which showed dense fibrosis with a sparse inflammatory infiltrate, similar to the pathologic pattern observed in the skin biopsy. With methotrexate and systemic steroids, joint contractures slowly improved in the first patient and remained stable in the second. These 2 cases suggest that fibrous synovitis should be considered in children with acquired diffuse, symmetric, painless contractures and without elevation of acute-phase reactants, even in the absence of cutaneous manifestations. Articular MRI with gadolinium and careful cutaneous examination at onset and during follow-up should provide clues for diagnosing this entity.
[Mh] Termos MeSH primário: Artrite Juvenil/diagnóstico
Contratura/etiologia
Esclerodermia Localizada/diagnóstico
Sinovite/diagnóstico
[Mh] Termos MeSH secundário: Artrite Juvenil/complicações
Artrite Juvenil/patologia
Biópsia
Criança
Pré-Escolar
Fibrose
Seres Humanos
Imagem por Ressonância Magnética
Masculino
Esclerodermia Localizada/complicações
Esclerodermia Localizada/patologia
Sinovite/complicações
Sinovite/patologia
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171012
[Lr] Data última revisão:
171012
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:170929
[St] Status:MEDLINE


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[PMID]:28836421
[Au] Autor:Peng S; Sun X; Sun M
[Ad] Endereço:First Affiliated Hospital of China Medical University, Shenyang, China sxr679@126.com
[Ti] Título:Adalimumab for Uveitis in Juvenile Idiopathic Arthritis.
[So] Source:N Engl J Med;377(8):789, 2017 08 24.
[Is] ISSN:1533-4406
[Cp] País de publicação:United States
[La] Idioma:eng
[Mh] Termos MeSH primário: Adalimumab
Artrite Juvenil
[Mh] Termos MeSH secundário: Seres Humanos
Uveíte
[Pt] Tipo de publicação:LETTER; COMMENT
[Nm] Nome de substância:
FYS6T7F842 (Adalimumab)
[Em] Mês de entrada:1708
[Cu] Atualização por classe:170828
[Lr] Data última revisão:
170828
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:170825
[St] Status:MEDLINE
[do] DOI:10.1056/NEJMc1708646


  9 / 9122 MEDLINE  
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[PMID]:28834482
[Au] Autor:Ramanan AV; Dick AD; Beresford MW
[Ad] Endereço:University of Bristol, Bristol, United Kingdom
[Ti] Título:Adalimumab for Uveitis in Juvenile Idiopathic Arthritis.
[So] Source:N Engl J Med;377(8):789-790, 2017 08 24.
[Is] ISSN:1533-4406
[Cp] País de publicação:United States
[La] Idioma:eng
[Mh] Termos MeSH primário: Adalimumab
Artrite Juvenil
[Mh] Termos MeSH secundário: Antirreumáticos
Seres Humanos
Uveíte
[Pt] Tipo de publicação:LETTER; COMMENT
[Nm] Nome de substância:
0 (Antirheumatic Agents); FYS6T7F842 (Adalimumab)
[Em] Mês de entrada:1708
[Cu] Atualização por classe:170828
[Lr] Data última revisão:
170828
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:170824
[St] Status:MEDLINE
[do] DOI:10.1056/NEJMc1708646


  10 / 9122 MEDLINE  
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[PMID]:28822720
[Au] Autor:Kinard BE; Abramowicz S
[Ad] Endereço:Resident, Department of Surgery, Division of Oral and Maxillofacial Surgery, Emory University School of Medicine, Atlanta, GA.
[Ti] Título:Juvenile Idiopathic Arthritis Practice Patterns Among Oral and Maxillofacial Surgeons.
[So] Source:J Oral Maxillofac Surg;75(11):2333.e1-2333.e8, 2017 Nov.
[Is] ISSN:1531-5053
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:PURPOSE: The purpose of this investigation is to assess the current clinical practices by oral and maxillofacial surgeons (OMSs) in the United States regarding diagnosis and treatment of temporomandibular joint (TMJ) involvement in children with juvenile idiopathic arthritis (JIA). MATERIALS AND METHODS: We implemented a cross-sectional survey of academic OMSs in the United States via an electronic survey. The survey included respondent demographic data, patient volumes, diagnostic methods, and management practices for children with JIA and TMJ involvement. The results of the survey were analyzed using descriptive statistics. RESULTS: The study respondents were composed of 52 surgeons. Most respondents were men (n = 43, 87.8%), were aged 51 to 60 years (n = 20, 39.2%), were in full-time academics (n = 42, 84%), had more than 20 years of experience (n = 26, 50%), and were seeing 1 to 5 patients with JIA per month (n = 21, 46.7%). Most patients were aged 11 to 15 years (n = 22, 61.1%) and were managed with 1 to 2 systemic medications (n = 30, 81.1%). All OMSs reported evaluating TMJ involvement by reviewing patient history, clinical examination, and imaging. The most commonly used imaging modality was panoramic radiographs (n = 24, 63.2%) and magnetic resonance imaging (n = 22, 57.9%). OMSs decided to inject intra-articular medication based on history and symptoms (n = 36, 94.7%). Once in remission, patients were followed up at yearly (n = 12, 36.4%) or 6-month (n = 10, 30.3%) intervals. CONCLUSIONS: Our study shows that, in general, there is consensus among US OMSs regarding diagnosis of TMJ involvement in children with JIA. There is less concordance among the respondents regarding treatment. Currently, management of TMJ involvement in children with JIA is mostly based on expert opinions and retrospective studies. This study further highlights the need for randomized clinical trials and multi-institution collaboration to allow for evidence-based diagnosis and treatment.
[Mh] Termos MeSH primário: Artrite Juvenil/complicações
Padrões de Prática Médica
Cirurgia Bucal
Transtornos da Articulação Temporomandibular/diagnóstico
Transtornos da Articulação Temporomandibular/terapia
[Mh] Termos MeSH secundário: Adulto
Criança
Estudos Transversais
Feminino
Seres Humanos
Masculino
Meia-Idade
Autorrelato
Transtornos da Articulação Temporomandibular/etiologia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1711
[Cu] Atualização por classe:171109
[Lr] Data última revisão:
171109
[Sb] Subgrupo de revista:AIM; D; IM
[Da] Data de entrada para processamento:170821
[St] Status:MEDLINE



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