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[PMID]:29357386
[Au] Autor:Párraga Ros E; Correa-Martín L; Sánchez-Margallo FM; Candanosa-Aranda IE; Malbrain MLNG; Wise R; Latorre R; López Albors O; Castellanos G
[Ad] Endereço:Department of Anatomy and Comparative Pathology, Veterinary Faculty, University of Murcia, Murcia, Spain.
[Ti] Título:Time-course evaluation of intestinal structural disorders in a porcine model of intra-abdominal hypertension by mechanical intestinal obstruction.
[So] Source:PLoS One;13(1):e0191420, 2018.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: A mechanical intestinal obstruction (MIO) can generate intraabdominal hypertension (IAH) that is life threatening. The intestines are very sensitive to IAH since the low splanchnic perfusion causes intestinal hypoxia, local acidosis and bacterial translocations. This may lead to acute intestinal distress syndrome (AIDS). The identification of intestinal injuries during IAH and its correlation with clinical parameters as the abdominal perfusion pressure (APP), the gastric intramucosal pH (pHi) and lactic acid (Lc) are still unknown. This study aimed to evaluate the sequence of intestinal histopathological findings in an MIO model and to analyze potential relationships with parameters currently used in clinical practice (APP, pHi and Lc). MATERIAL AND METHODS: Twenty pigs were divided into three groups: a control group (n = 5) and two experimental groups with 20 mmHg (G1, n = 10) and 30 mmHg (G2, n = 5) of IAH by MIO. The pressures were maintained for 3 hours, except in 5 animals in G1 where it was maintained for 5 hours. The APP, pHi and LA were recorded and biopsies of the terminal ileum were taken every 30 minutes in all groups. The intestinal damage was graded according to the Park Score. RESULTS: Intestinal injuries were found in 42.9% of pigs in the experimental groups. The lesions were independent of the level and duration of IAH. Although APP and pHi were slightly lower in injured animals (I +) of G1 and G2, there were no significant differences among those uninjured (I-). Lc was significantly increased in all I+ pigs from the onset of IAH. CONCLUSION: The IAH by MIO causes intestinal lesions from the first 30 minutes with concurrent decreases in APP and pHi and increases in Lc. Lc could be the best clinical parameter related to intestinal damages with a clear difference between I + and I- animals.
[Mh] Termos MeSH primário: Obstrução Intestinal/complicações
Intestinos/patologia
Hipertensão Intra-Abdominal/complicações
Hipertensão Intra-Abdominal/patologia
Fenômenos Mecânicos
[Mh] Termos MeSH secundário: Animais
Modelos Animais de Doenças
Feminino
Suínos
Fatores de Tempo
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180226
[Lr] Data última revisão:
180226
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180123
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0191420


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[PMID]:28542443
[Au] Autor:Santos CL; Santos RS; Moraes L; Samary CS; Felix NS; Silva JD; Morales MM; Huhle R; Abreu MG; Schanaider A; Silva PL; Pelosi P; Rocco PRM
[Ad] Endereço:Laboratory of Pulmonary Investigation, Carlos Chagas Filho Institute of Biophysics, Federal University of Rio de Janeiro, Av. Carlos Chagas Filho, s/n, Bloco G-014, Ilha do Fundão, Rio de Janeiro, RJ, Brazil.
[Ti] Título:Effects of pressure support and pressure-controlled ventilation on lung damage in a model of mild extrapulmonary acute lung injury with intra-abdominal hypertension.
[So] Source:PLoS One;12(5):e0178207, 2017.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Intra-abdominal hypertension (IAH) may co-occur with the acute respiratory distress syndrome (ARDS), with significant impact on morbidity and mortality. Lung-protective controlled mechanical ventilation with low tidal volume and positive end-expiratory pressure (PEEP) has been recommended in ARDS. However, mechanical ventilation with spontaneous breathing activity may be beneficial to lung function and reduce lung damage in mild ARDS. We hypothesized that preserving spontaneous breathing activity during pressure support ventilation (PSV) would improve respiratory function and minimize ventilator-induced lung injury (VILI) compared to pressure-controlled ventilation (PCV) in mild extrapulmonary acute lung injury (ALI) with IAH. Thirty Wistar rats (334±55g) received Escherichia coli lipopolysaccharide intraperitoneally (1000µg) to induce mild extrapulmonary ALI. After 24h, animals were anesthetized and randomized to receive PCV or PSV. They were then further randomized into subgroups without or with IAH (15 mmHg) and ventilated with PCV or PSV (PEEP = 5cmH2O, driving pressure adjusted to achieve tidal volume = 6mL/kg) for 1h. Six of the 30 rats were used for molecular biology analysis and were not mechanically ventilated. The main outcome was the effect of PCV versus PSV on mRNA expression of interleukin (IL)-6 in lung tissue. Regardless of whether IAH was present, PSV resulted in lower mean airway pressure (with no differences in peak airway or peak and mean transpulmonary pressures) and less mRNA expression of biomarkers associated with lung inflammation (IL-6) and fibrogenesis (type III procollagen) than PCV. In the presence of IAH, PSV improved oxygenation; decreased alveolar collapse, interstitial edema, and diffuse alveolar damage; and increased expression of surfactant protein B as compared to PCV. In this experimental model of mild extrapulmonary ALI associated with IAH, PSV compared to PCV improved lung function and morphology and reduced type 2 epithelial cell damage.
[Mh] Termos MeSH primário: Lesão Pulmonar Aguda/complicações
Hipertensão Intra-Abdominal/complicações
Respiração com Pressão Positiva/métodos
[Mh] Termos MeSH secundário: Lesão Pulmonar Aguda/terapia
Animais
Modelos Animais de Doenças
Hipertensão Intra-Abdominal/terapia
Ratos
Ratos Wistar
Reação em Cadeia da Polimerase em Tempo Real
Respiração Artificial/métodos
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170912
[Lr] Data última revisão:
170912
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170526
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0178207


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[PMID]:28478881
[Au] Autor:Harrell BR; Miller S
[Ad] Endereço:Loewenberg College of Nursing, University of Memphis, Community Health Building, Office 3525, 4055 North Park Loop, Memphis, TN 38152, USA; Nursing Management Guidelines Workgroup for Intra-Abdominal Hypertension and Abdominal Compartment Syndrome, WSACS - the Abdominal Compartment Society, PO Box 980454, Richmond, VA 23298-0454, USA. Electronic address: bharrell@memphis.edu.
[Ti] Título:Abdominal Compartment Syndrome as a Complication of Fluid Resuscitation.
[So] Source:Nurs Clin North Am;52(2):331-338, 2017 Jun.
[Is] ISSN:1558-1357
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Fluid resuscitation is a primary concern of nurse clinicians. Excessive resuscitation with crystalloids places patients at particular risk for many subsequent complications that carry associated increases in mortality and morbidity. Intra-abdominal hypertension and abdominal compartment syndrome are deadly complications of third spacing and capillary leak that occur secondary to excessive fluid resuscitation. Careful consideration is necessary when achieving fluid balance in acutely ill patients, including reducing the use of crystalloids, implementing damage control resuscitation, and establishing measurable resuscitation endpoints. Nurse clinicians are capable of reducing mortality in intra-abdominal hypertension and abdominal compartment syndrome patients by incorporating the latest evidence in fluid resuscitation techniques.
[Mh] Termos MeSH primário: Estado Terminal/terapia
Hidratação/efeitos adversos
Hipertensão Intra-Abdominal/etiologia
Hipertensão Intra-Abdominal/terapia
Soluções Isotônicas/efeitos adversos
[Mh] Termos MeSH secundário: Seres Humanos
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Nm] Nome de substância:
0 (Isotonic Solutions); 0 (crystalloid solutions)
[Em] Mês de entrada:1705
[Cu] Atualização por classe:170515
[Lr] Data última revisão:
170515
[Sb] Subgrupo de revista:AIM; IM; N
[Da] Data de entrada para processamento:170509
[St] Status:MEDLINE


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[PMID]:28445278
[Au] Autor:Le-Xiang Z; Yao-Hao W; Na L; Rong-Lin Q; Jia-Jia Z; Wen-Li J; Jie Z; Xiao-Geng D
[Ad] Endereço:aDepartment of Pediatric Surgery bDepartment of Endocrinology, Sun Yat-sen Memorial Hospital, Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation Medical Research Center, Sun Yat-sen University, Guangzhou, China.
[Ti] Título:Analysis of treatment of large abdominal malignancies in children complicated with abdominal compartment syndrome: Report of six cases.
[So] Source:Medicine (Baltimore);96(17):e6705, 2017 Apr.
[Is] ISSN:1536-5964
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:To explore effective treatment of large abdominal malignancies in children complicated with abdominal compartment syndrome (ACS).Six children with large abdominal malignancies complicated with ACS were admitted to our department from January 2013 to January 2016, and the changes in their breathing, heart rate, oxygen saturation, abdominal circumference, bladder pressure, and urine output, as well as the treatment measures and outcomes, were retrospectively analyzed.The 6 children included 1 child with bilateral nephroblastoma, 1 child with abdominal alveolar rhabdomyosarcoma, 1 child with right ovarian malignant teratoma complicated with abdominal glioma, 1 child with abdominal malignant teratoma, 1 child with right nephroblastoma, and 1 child with left adrenal gland neuroblastoma. All patients were treated in a timely manner. The first 4 children underwent abdominal cavity decompression through surgical resection of the tumor, and the ACS was successfully cured allowing for follow-up care, whereas the last 2 patients failed to receive emergency surgery and eventually died due to the gradual aggravation of ACS.Decompression through surgical resection of the tumor is the only effective measure for treating large abdominal malignancies in children complicated with ACS.
[Mh] Termos MeSH primário: Neoplasias Abdominais/complicações
Neoplasias Abdominais/terapia
Descompressão Cirúrgica
Hipertensão Intra-Abdominal/complicações
Hipertensão Intra-Abdominal/terapia
[Mh] Termos MeSH secundário: Neoplasias Abdominais/mortalidade
Neoplasias Abdominais/fisiopatologia
Neoplasias das Glândulas Suprarrenais/complicações
Neoplasias das Glândulas Suprarrenais/mortalidade
Neoplasias das Glândulas Suprarrenais/fisiopatologia
Neoplasias das Glândulas Suprarrenais/terapia
Pré-Escolar
Tratamento de Emergência
Feminino
Seguimentos
Glioma/complicações
Glioma/mortalidade
Glioma/fisiopatologia
Glioma/terapia
Seres Humanos
Lactente
Recém-Nascido
Hipertensão Intra-Abdominal/mortalidade
Hipertensão Intra-Abdominal/fisiopatologia
Masculino
Neuroblastoma/complicações
Neuroblastoma/mortalidade
Neuroblastoma/fisiopatologia
Neuroblastoma/terapia
Estudos Retrospectivos
Teratoma/complicações
Teratoma/mortalidade
Teratoma/fisiopatologia
Teratoma/terapia
Resultado do Tratamento
Tumor de Wilms/complicações
Tumor de Wilms/mortalidade
Tumor de Wilms/fisiopatologia
Tumor de Wilms/terapia
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE; OBSERVATIONAL STUDY
[Em] Mês de entrada:1706
[Cu] Atualização por classe:170601
[Lr] Data última revisão:
170601
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:170427
[St] Status:MEDLINE
[do] DOI:10.1097/MD.0000000000006705


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[PMID]:28372705
[Au] Autor:Jackson TJ
[Ti] Título:Editorial Commentary: Fluid Extravasation in Hip Arthroscopy-A Tough Case Just Got Much Worse.
[So] Source:Arthroscopy;33(4):881-882, 2017 04.
[Is] ISSN:1526-3231
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Hip arthroscopy has its complications like any other surgery, but abdominal compartment syndrome is unique to the hip and is a complication with devastating consequences. Avoidance is the rule.
[Mh] Termos MeSH primário: Artroscopia
Radiografia
[Mh] Termos MeSH secundário: Hipertensão Intra-Abdominal
[Pt] Tipo de publicação:EDITORIAL; COMMENT
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171006
[Lr] Data última revisão:
171006
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170405
[St] Status:MEDLINE


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[PMID]:28357400
[Au] Autor:Papakrivou E; Makris D; Manoulakas E; Mitroudi M; Tepetes K; Papazoglou K; Zakynthinos E
[Ad] Endereço:Department of Critical Care Medicine, University Hospital of Larissa, University of Thessaly School of Medicine, Larisa, Greece; Department of Pediatric Surgery, General Hospital of "G. Gennimatas", A' University Department, Aristotle University of Thessaloniki, Thessaloniki, Greece.
[Ti] Título:Intra-Abdominal Hypertension Causes Bacterial Growth in Lungs: An Animal Study.
[So] Source:Biomed Res Int;2017:4601348, 2017.
[Is] ISSN:2314-6141
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:To study the effect of intra-abdominal hypertension (IAH) on the frequency of pneumonia with an experimental study, thirteen Sprague-Dawley rats were included. Eight out of thirteen animals were randomly assigned to receive 10 ml of benzalkonium chloride 0.2% (megacolon group) and five animals received 10 ml NaCl 0.9% (controls). Animals were anaesthetized by intramuscular delivery of ketamine. The incidence of positivity for bacteria lung tissue cultures and mesenteric lymph node cultures was assessed at the 21st day after animals' sacrification, or before in case of death. All megacolon group animals presented progressive increase of the abdomen and increased IAP (≥10 mmHg) whereas the frequency of their evacuations was almost eliminated. Controls presented normal evacuations, no sign of abdominal distention, and normal IAP. In megacolon group animals, there was evidence of significant amount of bacteria in lung cultures. In contrast, no bacteria were found in control animals.
[Mh] Termos MeSH primário: Bactérias/patogenicidade
Hipertensão Intra-Abdominal/patologia
Pulmão/microbiologia
Pneumonia/microbiologia
[Mh] Termos MeSH secundário: Animais
Bactérias/classificação
Bactérias/isolamento & purificação
Compostos de Benzalcônio/toxicidade
Modelos Animais de Doenças
Seres Humanos
Hipertensão Intra-Abdominal/induzido quimicamente
Hipertensão Intra-Abdominal/complicações
Hipertensão Intra-Abdominal/microbiologia
Pulmão/patologia
Linfonodos/microbiologia
Linfonodos/patologia
Pneumonia/induzido quimicamente
Pneumonia/etiologia
Pneumonia/patologia
Ratos
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Benzalkonium Compounds)
[Em] Mês de entrada:1704
[Cu] Atualização por classe:170418
[Lr] Data última revisão:
170418
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170331
[St] Status:MEDLINE
[do] DOI:10.1155/2017/4601348


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[PMID]:28174355
[Au] Autor:Jalalzadeh M; Ghadiani MH
[Ad] Endereço:Department of Nephrology, Loghman-Hakim Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran. jmojgan1341@gmail.com.
[Ti] Título:Kidney Failure Due to Abdominal Compartment Syndrome Following Snakebite.
[So] Source:Iran J Kidney Dis;11(1):66-69, 2017 01.
[Is] ISSN:1735-8604
[Cp] País de publicação:Iran
[La] Idioma:eng
[Ab] Resumo:Treatment of snakebite complications is challenging, as it is difficult to distinguish what kind of antivenins should be used. Kidney failure as a result of rhabdomyolysis or hemolysis may happen due to accumulated fluids that increase the pressure in the abdomen. This case report describes acute kidney failure probably due to intra-abdominal hypertension following an unknown bite.
[Mh] Termos MeSH primário: Lesão Renal Aguda
Edema
Hipertensão Intra-Abdominal
Derrame Pleural
Mordeduras de Serpentes/complicações
[Mh] Termos MeSH secundário: Cavidade Abdominal/diagnóstico por imagem
Lesão Renal Aguda/diagnóstico
Lesão Renal Aguda/etiologia
Lesão Renal Aguda/fisiopatologia
Lesão Renal Aguda/terapia
Tratamento Conservador/métodos
Dispneia/diagnóstico
Dispneia/etiologia
Dispneia/terapia
Edema/diagnóstico
Edema/etiologia
Edema/fisiopatologia
Edema/terapia
Seres Humanos
Hipertensão Intra-Abdominal/complicações
Hipertensão Intra-Abdominal/diagnóstico
Pulmão/diagnóstico por imagem
Masculino
Meia-Idade
Derrame Pleural/diagnóstico
Derrame Pleural/etiologia
Derrame Pleural/fisiopatologia
Derrame Pleural/terapia
Avaliação de Sintomas/métodos
Resultado do Tratamento
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Em] Mês de entrada:1708
[Cu] Atualização por classe:170817
[Lr] Data última revisão:
170817
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170209
[St] Status:MEDLINE


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[PMID]:28151898
[Au] Autor:Muresan M; Muresan S; Brinzaniuc K; Voidazan S; Sala D; Jimborean O; Hussam AH; Bara T; Popescu G; Borz C; Neagoe R
[Ad] Endereço:aSurgery Clinic No. 2 bDepartment of Physiology cDepartment of Anatomy dDepartment of Epidemiology eCardiovascular Surgery Clinic, University of Medicine and Pharmacy of Tirgu Mures, Tirgu Mures, Romania.
[Ti] Título:How much does decompressive laparotomy reduce the mortality rate in primary abdominal compartment syndrome?: A single-center prospective study on 66 patients.
[So] Source:Medicine (Baltimore);96(5):e6006, 2017 Feb.
[Is] ISSN:1536-5964
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Contribution of decompressive laparotomy within the framework of the complex therapeutic algorithm of abdominal compartment syndrome (ACS) is cited with an extremely heterogeneous percentage in terms of survival. The purpose of this study was to present new data regarding contribution of each therapeutic step toward decreasing the mortality of this syndrome.This is a longitudinal prospective study including 134 patients with risk factors for ACS. The intra-abdominal pressure was measured every hour indirectly based on transvesical approach and the appearance of organ dysfunction. Specific therapy for ACS was based on the 2013 World Society of Abdominal Compartment Syndrome guidelines, which include laparotomy decompression. Management of the temporarily open abdomen included an assisted vacuum wound therapy.Of 134 patients, 66 developed ACS. The average intra-abdominal pressure significantly decreased after therapy and decompression surgery. The overall rate of mortality was 27.3% with statistical significance in necrotizing infected pancreatitis. Surgical decompression performed within the first 24 hours after the onset of ACS had a protective role against mortality (odds ratio <1). The average time after which laparotomy decompression was performed was 16.23 hours. The complications occurred during TAC were 2 wound suppurations and 1 intestinal obstruction. Wound suppurations evolved favorably by using vacuum wound-assisted therapy associated with the general treatment, whereas for occlusion, resurgery was performed after which adhesions dissolved. The final closure of the abdomen was performed at a mean of 11.7 days (min. = 9, max. = 14). The closure type was primary suture of the musculoaponeurotic edges in 4 cases, and the use of dual mesh in the other 11 cases.The highest mortality rate in the study group was registered in patients with necrotizing pancreatitis and the lowest in trauma group. Surgical decompression within the framework of the complex algorithm treatment of ACS contributed to the reduction of mortality by 8.7%. It is extremely important that the elapsed time since the initiation of the ACS until the surgical decompression is minimal (under 24 hours).
[Mh] Termos MeSH primário: Abdome/cirurgia
Descompressão Cirúrgica/mortalidade
Hipertensão Intra-Abdominal/mortalidade
Hipertensão Intra-Abdominal/cirurgia
[Mh] Termos MeSH secundário: Adulto
Idoso
Idoso de 80 Anos ou mais
Descompressão Cirúrgica/métodos
Feminino
Seres Humanos
Laparotomia
Estudos Longitudinais
Masculino
Meia-Idade
Estudos Prospectivos
Fatores de Risco
Taxa de Sobrevida
Técnicas de Sutura
Tempo para o Tratamento
Resultado do Tratamento
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1702
[Cu] Atualização por classe:170224
[Lr] Data última revisão:
170224
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:170203
[St] Status:MEDLINE
[do] DOI:10.1097/MD.0000000000006006


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[PMID]:28121282
[Au] Autor:Leclerc B; Salomon Du Mont L; Besch G; Rinckenbach S
[Ad] Endereço:1 Vascular Surgery Unit, University Hospital of Besançon, Besançon, France.
[Ti] Título:How to identify patients at risk of abdominal compartment syndrome after surgical repair of ruptured abdominal aortic aneurysms in the operating room: A pilot study.
[So] Source:Vascular;25(5):472-478, 2017 Oct.
[Is] ISSN:1708-539X
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Objectives Abdominal compartment syndrome (ACS) is poorly identified in surgery for ruptured abdominal aortic aneurysm and an early management is crucial. The aim of this study was to validate how many risk factors were needed to predict ACS. Secondary objectives were to assess its prevalence and the 30-day mortality. Methods All patients operated for ruptured abdominal aortic aneurysm during 5 years were included. An independent committee performed a retrospective diagnosis of ACS. Eight criteria were selected from the literature, and corresponded to pre- and intraoperative period: anemia (hemoglobin lower than 10 g/dL), prolonged shock (systolic blood pressure <90 mmHg more than 18 min), preoperative cardiac arrest, obesity (body mass index > 30), massive fluid resuscitation (≥3500 mL per hour for at least 1 h) and transfusions (>10 units packed blood red cell since the beginning of the treatment), severe hypothermia (≤33℃), acidosis (pH < 7.2). Sensitivity and specificity were assessed for each number of criteria. Results Eight patients were ACS+ and 28 ACS-, with three criteria for ACS+ and 1.5 for ACS- ( p = 0.002). Three criteria among the eight selected criteria have the best cutoff for sensitivity and specificity (75% and 82%) with a positive predictive value of 54% and a negative predictive value of 92%. The prevalence of ACS was 17%. The 30-day mortality in ACS+ tended to be higher than in ACS- ( p = 0.108). Conclusion The present results suggest that patients with an ACS seemed to have higher mortality and the threshold of three factors among eight specific factors is enough to predict this.
[Mh] Termos MeSH primário: Aneurisma da Aorta Abdominal/cirurgia
Ruptura Aórtica/cirurgia
Hipertensão Intra-Abdominal/etiologia
Salas Cirúrgicas
Procedimentos Cirúrgicos Vasculares/efeitos adversos
[Mh] Termos MeSH secundário: Idoso
Idoso de 80 Anos ou mais
Aneurisma da Aorta Abdominal/diagnóstico por imagem
Aneurisma da Aorta Abdominal/mortalidade
Ruptura Aórtica/diagnóstico por imagem
Ruptura Aórtica/mortalidade
Área Sob a Curva
Diagnóstico Precoce
Feminino
França/epidemiologia
Seres Humanos
Hipertensão Intra-Abdominal/diagnóstico
Hipertensão Intra-Abdominal/mortalidade
Masculino
Meia-Idade
Projetos Piloto
Valor Preditivo dos Testes
Prevalência
Curva ROC
Reprodutibilidade dos Testes
Estudos Retrospectivos
Medição de Risco
Fatores de Risco
Fatores de Tempo
Resultado do Tratamento
Procedimentos Cirúrgicos Vasculares/mortalidade
[Pt] Tipo de publicação:JOURNAL ARTICLE; OBSERVATIONAL STUDY
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171030
[Lr] Data última revisão:
171030
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170126
[St] Status:MEDLINE
[do] DOI:10.1177/1708538116689005


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[PMID]:28121035
[Au] Autor:Soop M; Carlson GL
[Ad] Endereço:Intestinal Failure Unit, University of Manchester, Manchester Academic Health Science Centre, Salford Royal NHS Foundation Trust, Manchester, UK.
[Ti] Título:Recent developments in the surgical management of complex intra-abdominal infection.
[So] Source:Br J Surg;104(2):e65-e74, 2017 Jan.
[Is] ISSN:1365-2168
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Current guidance on the management of sepsis often applies to infection originating from abdominal or pelvic sources, which presents specific challenges and opportunities for efficient and rapid source control. Advances made in the past decade are presented in this article. METHODS: A qualitative systematic review was undertaken by searching standard literature databases for English-language studies presenting original data on the clinical management of abdominal and pelvic complex infection in adults over the past 10 years. High-quality studies relevant to five topical themes that emerged during review were included. RESULTS: Important developments and promising preliminary work are presented, relating to: imaging and other diagnostic modalities; antimicrobial therapy and the importance of antimicrobial stewardship; the particular challenges posed by fungal sepsis; novel techniques in percutaneous and endoscopic source control; and current issues relating to surgical source control and managing the abdominal wound. Logistical challenges relating to rapid access to cross-sectional imaging, interventional radiology and operating theatres need to be addressed so that international benchmarks can be met. CONCLUSION: Important advances have been made in the diagnosis, non-operative and surgical control of abdominal or pelvic sources, which may improve outcomes in the future. Important areas for continued research include the diagnosis and therapy of fungal infection and the challenges of managing the open abdomen.
[Mh] Termos MeSH primário: Infecções Intra-Abdominais/terapia
[Mh] Termos MeSH secundário: Técnicas de Fechamento de Ferimentos Abdominais
Antibacterianos/uso terapêutico
Diagnóstico por Imagem
Drenagem/métodos
Seres Humanos
Hipertensão Intra-Abdominal/prevenção & controle
Infecções Intra-Abdominais/diagnóstico
Micoses/diagnóstico
Tratamento de Ferimentos com Pressão Negativa
Reoperação
Sepse/diagnóstico
Sepse/terapia
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Nm] Nome de substância:
0 (Anti-Bacterial Agents)
[Em] Mês de entrada:1704
[Cu] Atualização por classe:170817
[Lr] Data última revisão:
170817
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:170126
[St] Status:MEDLINE
[do] DOI:10.1002/bjs.10437



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