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[PMID]:28807406
[Au] Autor:Merlocco A; Lacro RV; Gauvreau K; Rabideau N; Singh MN; Prakash A
[Ad] Endereço:Department of Cardiology, Boston Children's Hospital, Boston, Massachusetts; Department of Pediatrics, Harvard Medical School, Boston, Massachusetts.
[Ti] Título:Longitudinal Changes in Segmental Aortic Stiffness Determined by Cardiac Magnetic Resonance in Children and Young Adults With Connective Tissue Disorders (the Marfan, Loeys-Dietz, and Ehlers-Danlos Syndromes, and Nonspecific Connective Tissue Disorders).
[So] Source:Am J Cardiol;120(7):1214-1219, 2017 Oct 01.
[Is] ISSN:1879-1913
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Aortic stiffness measured by cardiac magnetic resonance (CMR) in connective tissue disorder (CTD) patients has been previously shown to be abnormal and to be associated with adverse aortic outcomes. The rate of increase in aortic stiffness with normal aging has been previously described. However, longitudinal changes in aortic stiffness have not been characterized in CTD patients. We examined longitudinal changes in CMR-derived aortic stiffness in children and young adults with CTDs. A retrospective analysis of 50 children and young adults (median age, 20 years; range, 0.2 to 49; 40% < 18 years old) with a CTD, and with at least 2 CMR examinations (total 152 examinations) over a median duration of 3.9 (1 to 13.2) years was performed. Aortic stiffness measures (strain, distensibility, and ß stiffness index) were calculated on each examination at the aortic root (AoR), ascending aorta, and descending aorta. Longitudinal changes in parameters were analyzed using linear mixed-effects models. Aortic strain and distensibility decreased with age, whereas the ß stiffness index increased at all aortic segments. The average rates of decline in distensibility (x10 mm Hg per 10-year increase in age) were 0.7, 1.3, and 1 at the AoR, ascending aorta, and descending aorta, respectively. The rates of decline in distensibility were not associated with the rates of AoR dilation or surgical AoR replacement. In conclusion, on serial CMR measurements in children and young adults with CTDs, aortic stiffness progressively increased with age, with rates of change only slightly higher than those previously reported in healthy adults.
[Mh] Termos MeSH primário: Aorta Torácica/patologia
Aorta/patologia
Doenças do Tecido Conjuntivo/diagnóstico
Imagem Cinética por Ressonância Magnética/métodos
Rigidez Vascular
[Mh] Termos MeSH secundário: Adolescente
Adulto
Aorta/fisiopatologia
Aorta Torácica/fisiopatologia
Criança
Pré-Escolar
Doenças do Tecido Conjuntivo/fisiopatologia
Síndrome de Ehlers-Danlos/diagnóstico
Síndrome de Ehlers-Danlos/fisiopatologia
Feminino
Seguimentos
Seres Humanos
Lactente
Síndrome de Loeys-Dietz/diagnóstico
Síndrome de Loeys-Dietz/fisiopatologia
Masculino
Síndrome de Marfan/diagnóstico
Síndrome de Marfan/fisiopatologia
Meia-Idade
Estudos Retrospectivos
Índice de Gravidade de Doença
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170914
[Lr] Data última revisão:
170914
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:170816
[St] Status:MEDLINE


  2 / 216 MEDLINE  
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[PMID]:28633258
[Au] Autor:Hashizume K; Shimizu H; Honda M; Inoue S; Takaki H; Hayashi K; Kaneyama H
[Ad] Endereço:Department of Cardiovascular Surgery, Saiseikai Utsunomiya Hospital, Utsunomiya, Tochigi, Japan. Electronic address: kenichihszm@mac.com.
[Ti] Título:Stepwise Total Aortic Repairs With Fenestrated Endografts in a Patient With Loeys-Dietz Syndrome.
[So] Source:Ann Thorac Surg;104(1):e39-e42, 2017 Jul.
[Is] ISSN:1552-6259
[Cp] País de publicação:Netherlands
[La] Idioma:eng
[Ab] Resumo:Loeys-Dietz syndrome (LDS) is a rare connective tissue disorder (CTD) caused by mutations in the gene encoding transforming growth factor-ß receptors â…  and â…¡. Patients with LDS manifest spontaneous aneurysms and dissections of the aorta and peripheral artery. We report a successful treatment with a hybrid endovascular repair for a rapidly expanding thoracoabdominal aneurysm in a 41-year-old woman affected by LDS. To overcome the difficulties of anatomical and surgical repair, we applied an original strategy using surgeon-modified fenestrated endografts.
[Mh] Termos MeSH primário: Aorta Torácica/cirurgia
Aneurisma da Aorta Torácica/cirurgia
Prótese Vascular
Procedimentos Endovasculares/métodos
Síndrome de Loeys-Dietz/complicações
[Mh] Termos MeSH secundário: Adulto
Aorta Torácica/diagnóstico por imagem
Aneurisma da Aorta Torácica/diagnóstico
Aneurisma da Aorta Torácica/etiologia
Feminino
Seres Humanos
Síndrome de Loeys-Dietz/diagnóstico
Síndrome de Loeys-Dietz/cirurgia
Desenho de Prótese
Tomografia Computadorizada por Raios X
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170901
[Lr] Data última revisão:
170901
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:170622
[St] Status:MEDLINE


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[PMID]:28366467
[Au] Autor:Patel ND; Alejo D; Crawford T; Hibino N; Dietz HC; Cameron DE; Vricella LA
[Ad] Endereço:Division of Cardiac Surgery, Department of Surgery, The Johns Hopkins Medical Institutions, Baltimore, Maryland.
[Ti] Título:Aortic Root Replacement for Children With Loeys-Dietz Syndrome.
[So] Source:Ann Thorac Surg;103(5):1513-1518, 2017 May.
[Is] ISSN:1552-6259
[Cp] País de publicação:Netherlands
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Loeys-Dietz syndrome (LDS) is an aggressive aortopathy with a proclivity for aortic aneurysm rupture and dissection at smaller diameters than other connective tissue disorders. We reviewed our surgical experience of children with LDS to validate our guidelines for prophylactic aortic root replacement (ARR). METHODS: We reviewed all children (younger than 18 years) with a diagnosis of LDS who underwent ARR at our institution. The primary endpoint was mortality, and secondary endpoints included complications and the need for further interventions. RESULTS: Thirty-four children with LDS underwent ARR. Mean age at operation was 10 years, and 15 (44%) were female. Mean preoperative root diameter was 4 cm. Three children (9%) had composite ARR with a mechanical prosthesis, and 31 (91%) underwent valve-sparing ARR. Concomitant procedures included arch replacement in 2 (6%), aortic valve repair in 1 (3%), and patent foramen ovale closure in 16 (47%). There was no operative mortality. Two children (6%) required late replacement of the ascending aorta, 5 (15%) required arch replacement, 1 (3%) required mitral valve replacement, and 2 (6%) had coronary button aneurysms/pseudoaneurysms requiring repair. Three children required redo valve-sparing ARR after a Florida sleeve procedure, and 2 had progressive aortic insufficiency requiring aortic valve replacement after a valve-sparing procedure. There were 2 late deaths (6%). CONCLUSIONS: These data confirm the aggressive aortopathy of LDS. Valve-sparing ARR should be performed when feasible to avoid the risks of prostheses. Serial imaging of the arterial tree is critical, given the rate of subsequent intervention.
[Mh] Termos MeSH primário: Aorta/cirurgia
Síndrome de Loeys-Dietz/cirurgia
Enxerto Vascular
[Mh] Termos MeSH secundário: Aorta/diagnóstico por imagem
Aorta/patologia
Valva Aórtica/cirurgia
Insuficiência da Valva Aórtica/cirurgia
Prótese Vascular
Criança
Feminino
Forame Oval Patente/cirurgia
Seres Humanos
Estimativa de Kaplan-Meier
Síndrome de Loeys-Dietz/mortalidade
Masculino
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1708
[Cu] Atualização por classe:170811
[Lr] Data última revisão:
170811
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:170404
[St] Status:MEDLINE


  4 / 216 MEDLINE  
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[PMID]:28344185
[Au] Autor:Valenzuela I; Fernández-Alvarez P; Munell F; Sanchez-Montanez A; Giralt G; Vendrell T; Tizzano EF
[Ad] Endereço:Department of Clinical and Molecular Genetics and Rare Disease Unit, University Hospital Vall d'Hebron, CIBERER, Barcelona, Spain.
[Ti] Título:Arthrogryposis as neonatal presentation of Loeys-Dietz syndrome due to a novel TGFBR2 mutation.
[So] Source:Eur J Med Genet;60(6):303-307, 2017 Jun.
[Is] ISSN:1878-0849
[Cp] País de publicação:Netherlands
[La] Idioma:eng
[Ab] Resumo:Loeys-Dietz syndrome (LDS) is an autosomal dominant connective tissue disorder characterized mainly by cardiovascular, craniofacial and skeletal features. We report on a patient with LDS, whose prenatal examination was compatible with the diagnosis of arthrogryposis multiplex congenita. Neonatal assessment showed craniofacial and cardiovascular findings suggestive of LDS whose diagnosis was confirmed by the detection of a novel mutation (HGVN: NM_003242.5 (TGFBR2): c.1381T > C (p.(Cys461Arg))) in the TGFBR2 gene. Few prenatal and neonatal cases of LDS have been reported in the literature. We reviewed all cases reported to date with perinatal onset to delineate the clinical manifestations that allow us to prompt diagnosis of this syndrome at an early stage to prevent fatal cardiovascular complications. Furthermore we discuss the multidisciplinary follow up required in these patients.
[Mh] Termos MeSH primário: Artrogripose/genética
Síndrome de Loeys-Dietz/genética
Mutação de Sentido Incorreto
Proteínas Serina-Treonina Quinases/genética
Receptores de Fatores de Crescimento Transformadores beta/genética
[Mh] Termos MeSH secundário: Artrogripose/diagnóstico
Feminino
Seres Humanos
Recém-Nascido
Síndrome de Loeys-Dietz/diagnóstico
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE; REVIEW
[Nm] Nome de substância:
0 (Receptors, Transforming Growth Factor beta); EC 2.7.11.1 (Protein-Serine-Threonine Kinases); EC 2.7.11.30 (transforming growth factor-beta type II receptor)
[Em] Mês de entrada:1708
[Cu] Atualização por classe:170807
[Lr] Data última revisão:
170807
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170328
[St] Status:MEDLINE


  5 / 216 MEDLINE  
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[PMID]:28304197
[Au] Autor:Aoki R; Srivatanakul K; Osada T; Hotta K; Sorimachi T; Matsumae M; Morisaki H
[Ad] Endereço:1 Tokai University, Japan.
[Ti] Título:Endovascular treatment of a dural arteriovenous fistula in a patient with Loeys-Dietz syndrome: A case report.
[So] Source:Interv Neuroradiol;23(2):206-210, 2017 Apr.
[Is] ISSN:2385-2011
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Background Loeys-Dietz syndrome (LDS) is a recently recognized autosomal dominant connective tissue disease. The manifestations of LDS include vascular tortuosity, scoliosis, craniosynostosis, aneurysm and aortic dissections. Clinical presentation A 35-year-old woman treated with Stanford type B aortic dissection and breast cancer was referred to us for Borden type II dural arteriovenous fistula (dAVF) draining to the vein of Galen, involving the midline of tentorium cerebelli. The dAVF was treated successfully by combined transarterial and transvenous embolization. Because of tortuosity of vertebral arteries, a genetic test was conducted confirming LDS type 2. Conclusions To our knowledge, this is the first case report of dAVF associated with LDS. The relationship between LDS and dAVF is unknown but this report shows the possibility that mutation of transforming growth factor ß receptors 2 ( TGFBR2) related to LDS may be related to shunt diseases. Because intervention in LDS seems to be feasible compared to Ehlers Danlos syndrome and Marfan syndrome, it is important to make the correct diagnosis.
[Mh] Termos MeSH primário: Malformações Vasculares do Sistema Nervoso Central/terapia
Embolização Terapêutica/métodos
Síndrome de Loeys-Dietz/complicações
[Mh] Termos MeSH secundário: Malformações Vasculares do Sistema Nervoso Central/diagnóstico por imagem
Angiografia Cerebral
Diagnóstico Diferencial
Feminino
Seres Humanos
Imagem por Ressonância Magnética
Meia-Idade
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171023
[Lr] Data última revisão:
171023
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170318
[St] Status:MEDLINE
[do] DOI:10.1177/1591019916686054


  6 / 216 MEDLINE  
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[PMID]:28252349
[Au] Autor:Harky A; Garner M; Roberts N
[Ad] Endereço:Barts Heart Centre, St. Bartholomew's Hospital, Barts Health NHS Trust , UK.
[Ti] Título:A late presentation of Loeys-Dietz syndrome associated with an aortic root aneurysm.
[So] Source:Ann R Coll Surg Engl;99(3):e114-e115, 2017 Mar.
[Is] ISSN:1478-7083
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Loeys-Dietz syndrome (LDS) is characterised by a mutation in the transforming growth factor beta receptor, and is strongly associated with aortic aneurysms and rupture. Most cases of LDS present in the second decade of life, with the average life expectancy being 37 years. We report a case of suspected LDS (owing to significant family history of the disorder) that presented in the seventh decade of life. Our patient had aortic root dilation and was initially believed to have Marfan syndrome. However, subsequent tests were negative. On further investigation of her family history, it was revealed that she had a strong positive family history of aortic rupture and aneurysms associated with genetically confirmed atypical LDS. By reporting this case, we aim to highlight the importance of considering inherited connective tissue disorders when a patient presents with aortic aneurysms or dissections associated with a strong family history of aortic pathology.
[Mh] Termos MeSH primário: Aneurisma da Aorta Torácica/diagnóstico por imagem
Insuficiência da Valva Aórtica/diagnóstico por imagem
Síndrome de Loeys-Dietz/diagnóstico por imagem
[Mh] Termos MeSH secundário: Idade de Início
Idoso
Aneurisma da Aorta Torácica/etiologia
Aneurisma da Aorta Torácica/cirurgia
Insuficiência da Valva Aórtica/etiologia
Insuficiência da Valva Aórtica/cirurgia
Prótese Vascular
Implante de Prótese Vascular
Angiografia por Tomografia Computadorizada
Angiografia Coronária
Ecoencefalografia
Feminino
Implante de Prótese de Valva Cardíaca
Seres Humanos
Síndrome de Loeys-Dietz/complicações
Síndrome de Loeys-Dietz/genética
Imagem por Ressonância Magnética
Mutação
Receptores de Fatores de Crescimento Transformadores beta/genética
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Receptors, Transforming Growth Factor beta)
[Em] Mês de entrada:1704
[Cu] Atualização por classe:170615
[Lr] Data última revisão:
170615
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170303
[St] Status:MEDLINE
[do] DOI:10.1308/rcsann.2017.0018


  7 / 216 MEDLINE  
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[PMID]:28209770
[Au] Autor:Woolnough R; Dhawan A; Dow K; Walia JS
[Ad] Endereço:Department of Pediatrics, and.
[Ti] Título:Are Patients With Loeys-Dietz Syndrome Misdiagnosed With Beals Syndrome?
[So] Source:Pediatrics;139(3), 2017 Mar.
[Is] ISSN:1098-4275
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Beals syndrome, also known as congenital contractural arachnodactyly (Online Mendelian Inheritance in Man: 121050), is an autosomal dominant disorder caused by a mutation in that is typically characterized by congenital contractures and arachnodactyly. It shares a number of phenotypic features with Loeys-Dietz syndrome (Online Mendelian Inheritance in Man: 609192). Loeys-Dietz syndrome, initially described in 2005, is associated with mutations for the transforming growth factor ß receptor and is characterized by findings of cerebral, thoracic, and abdominal arterial aneurysms. This report describes a 17-year-old male patient with a typical neonatal diagnosis of Beals syndrome. At age 15 years, an echocardiogram conducted in response to an aortic dissection in his father showed moderate aortic root dilation, prompting comprehensive testing for aortopathies, revealing a mutation in , thereby changing the diagnosis to Loeys-Dietz syndrome. Previously published reports have not implicated any mutation of the transforming growth factor ß receptor genes in cases of Beals syndrome. This case underscores that due to significant phenotypic overlap, there is utility in a full panel of testing, including genes for hereditary connective tissue disorders with vascular involvement, as well as Likewise, young patients who have tested negative for should be tested for hereditary connective tissue disorders with vascular involvement.
[Mh] Termos MeSH primário: Erros de Diagnóstico
Síndrome de Loeys-Dietz/diagnóstico
[Mh] Termos MeSH secundário: Adolescente
Doenças da Aorta/diagnóstico por imagem
Doenças da Aorta/genética
Aracnodactilia/diagnóstico
Contratura/diagnóstico
Diagnóstico Diferencial
Dilatação Patológica/diagnóstico por imagem
Dilatação Patológica/genética
Seres Humanos
Síndrome de Loeys-Dietz/genética
Masculino
Mutação
Proteínas Serina-Treonina Quinases/genética
Receptores de Fatores de Crescimento Transformadores beta/genética
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Receptors, Transforming Growth Factor beta); EC 2.7.1.11 (TGF-beta type I receptor); EC 2.7.11.1 (Protein-Serine-Threonine Kinases)
[Em] Mês de entrada:1706
[Cu] Atualização por classe:170628
[Lr] Data última revisão:
170628
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:170218
[St] Status:MEDLINE


  8 / 216 MEDLINE  
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[PMID]:28185953
[Au] Autor:Courtois A; Coppieters W; Bours V; Defraigne JO; Colige A; Sakalihasan N
[Ad] Endereço:Surgical Research Center, GIGA-R, Belgium; Department of Cardiovascular and Thoracic Surgery, University Hospital of Liège, Belgium. Electronic address: a.courtois@ulg.ac.be.
[Ti] Título:A novel SMAD3 mutation caused multiple aneurysms in a patient without osteoarthritis symptoms.
[So] Source:Eur J Med Genet;60(4):228-231, 2017 Apr.
[Is] ISSN:1878-0849
[Cp] País de publicação:Netherlands
[La] Idioma:eng
[Ab] Resumo:Heterozygous mutations in the SMAD3 gene were recently described as the cause of a form of non-syndromic familial aortic thoracic aneurysm and dissection (FTAAD) transmitted as an autosomal dominant disorder and often associated with early-onset osteoarthritis. This new clinical entity, called aneurysms-osteoarthritis syndrome (AOS) or Loeys-Dietz syndrome 3 (LDS3), is characterized by aggressive arterial damages such as aneurysms, dissections and tortuosity throughout the arterial tree. We report, here, the case of a 45 year-old man presenting multiple visceral arteries and abdominal aortic aneurysms but without dissection of the thoracic aorta and without any sign of osteoarthritis. Exome-sequencing revealed a new frameshift heterozygous c.455delC (p.Pro152Hisfs*34) mutation in the SMAD3 gene. This deletion is located in the exon 3 coding for the linker region of the protein and causes a premature stop codon at positions 556-558 in the exon 4. The same mutation was found in the proband's mother and sister who had open surgery for abdominal aortic aneurysm and in one of his children who was 5 year-old and did not present aneurysm yet.
[Mh] Termos MeSH primário: Aneurisma/genética
Síndrome de Loeys-Dietz/genética
Mutação
Osteoartrite/genética
Proteína Smad3/genética
[Mh] Termos MeSH secundário: Aneurisma Dissecante/genética
Aneurisma da Aorta Torácica/genética
Exoma
Éxons
Saúde da Família
Feminino
Mutação da Fase de Leitura
Heterozigoto
Seres Humanos
Masculino
Meia-Idade
Fenótipo
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (SMAD3 protein, human); 0 (Smad3 Protein)
[Em] Mês de entrada:1703
[Cu] Atualização por classe:170320
[Lr] Data última revisão:
170320
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170211
[St] Status:MEDLINE


  9 / 216 MEDLINE  
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[PMID]:28084959
[Au] Autor:Papagiannis J
[Ad] Endereço:Division of Cardiology,Children's Mercy Hospital,Kansas City, Missouri,United States of America.
[Ti] Título:Sudden death due to aortic pathology.
[So] Source:Cardiol Young;27(S1):S36-S42, 2017 Jan.
[Is] ISSN:1467-1107
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Sudden death from aortic dissection of an ascending aortic aneurysm is an uncommon but important finding in all series of sudden death in young, apparently healthy athletes. Individuals at risk include those having any of a variety of conditions in which structural weakness of the ascending aorta predisposes to pathological dilation under prolonged periods of increased wall stress. These conditions include Marfan syndrome, Loeys-Dietz syndrome, bicuspid aortic valve, and the vascular form of Ehlers-Danlos syndrome. Diagnostic criteria, surveillance strategies, medical management, and surgical indications are discussed. Finally, the current recommendations for sports participation are provided.
[Mh] Termos MeSH primário: Aorta/patologia
Atletas
Morte Súbita/etiologia
Síndrome de Ehlers-Danlos/complicações
Cardiopatias Congênitas/complicações
Síndrome de Loeys-Dietz/complicações
Síndrome de Marfan/complicações
[Mh] Termos MeSH secundário: Adolescente
Aneurisma Dissecante/fisiopatologia
Aneurisma Aórtico/fisiopatologia
Criança
Dilatação Patológica
Exercício
Guias como Assunto
Seres Humanos
Esportes
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Em] Mês de entrada:1702
[Cu] Atualização por classe:170214
[Lr] Data última revisão:
170214
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170114
[St] Status:MEDLINE
[do] DOI:10.1017/S1047951116002213


  10 / 216 MEDLINE  
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[PMID]:28082467
[Au] Autor:Yamana K; Sakurai H; Nonaka T; Sakurai T
[Ad] Endereço:Department of Cardiac Surgery, Nagoya Graduate School of Medicine, Nagoya, Japan.
[Ti] Título:Dilated cardiomyopathy associated with elephant trunk in Loeys-Dietz syndrome.
[So] Source:Eur J Cardiothorac Surg;51(4):797-798, 2017 Apr 01.
[Is] ISSN:1873-734X
[Cp] País de publicação:Germany
[La] Idioma:eng
[Ab] Resumo:A 14-year-old boy presented to our institution with a diagnosis of acute type A dissection. He was diagnosed with Loeys-Dietz syndrome and underwent aortic valve sparing repair at the age of 9 years. Emergency total arch repair with elephant trunk (ET) was performed successfully; echocardiogram before discharge showed normal left ventricular function and size. However, he was readmitted 1 month after discharge with significant left ventricular dysfunction and dilatation. The small folded ET caused a pressure gradient between the upper and lower body, which might deteriorate left ventricular function. Urgent balloon arterioplasty was performed to unfold the ET graft, resulting in no improvement of left ventricular function. ET removal and descending aorta replacement with an 18-mm graft was performed eventually. Left ventricular function and brain natriuretic peptide gradually improved after approximately 2 years of follow-up.
[Mh] Termos MeSH primário: Implante de Prótese Vascular/efeitos adversos
Cardiomiopatia Dilatada/etiologia
Síndrome de Loeys-Dietz/cirurgia
[Mh] Termos MeSH secundário: Doença Aguda
Adolescente
Implante de Prótese Vascular/métodos
Seres Humanos
Síndrome de Loeys-Dietz/diagnóstico por imagem
Masculino
Reoperação/métodos
Tomografia Computadorizada por Raios X
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171023
[Lr] Data última revisão:
171023
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170114
[St] Status:MEDLINE
[do] DOI:10.1093/ejcts/ezw376



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