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[PMID]:28705318
[Au] Autor:Seki A; Ishikawa T; Daumy X; Mishima H; Barc J; Sasaki R; Nishii K; Saito K; Urano M; Ohno S; Otsuki S; Kimoto H; Baruteau AE; Thollet A; Fouchard S; Bonnaud S; Parent P; Shibata Y; Perrin JP; Le Marec H; Hagiwara N; Mercier S; Horie M; Probst V; Yoshiura KI; Redon R; Schott JJ; Makita N
[Ad] Endereço:Department of Cardiology, Tokyo Women's Medical University, Tokyo, Japan; Support Center for Women Health Care Professionals and Researchers, Tokyo Women's Medical University, Tokyo, Japan.
[Ti] Título:Progressive Atrial Conduction Defects Associated With Bone Malformation Caused by a Connexin-45 Mutation.
[So] Source:J Am Coll Cardiol;70(3):358-370, 2017 Jul 18.
[Is] ISSN:1558-3597
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Inherited cardiac conduction disease is a rare bradyarrhythmia associated with mutations in various genes that affect action potential propagation. It is often characterized by isolated conduction disturbance of the His-Purkinje system, but it is rarely described as a syndromic form. OBJECTIVES: The authors sought to identify the genetic defect in families with a novel bradyarrhythmia syndrome associated with bone malformation. METHODS: The authors genetically screened 15 European cases with genotype-negative de novo atrioventricular (AV) block and their parents by trio whole-exome sequencing, plus 31 Japanese cases with genotype-negative familial AV block or sick sinus syndrome by targeted exon sequencing of 457 susceptibility genes. Functional consequences of the mutation were evaluated using an in vitro cell expression system and in vivo knockout mice. RESULTS: The authors identified a connexin-45 (Cx45) mutation (p.R75H) in 2 unrelated families (a de novo French case and a 3-generation Japanese family) who presented with progressive AV block, which resulted in atrial standstill without ventricular conduction abnormalities. Affected individuals shared a common extracardiac phenotype: a brachyfacial pattern, finger deformity, and dental dysplasia. Mutant Cx45 expressed in Neuro-2a cells showed normal hemichannel assembly and plaque formation. However, Lucifer yellow dye transfer and gap junction conductance between cell pairs were severely impaired, which suggested that mutant Cx45 impedes gap junction communication in a dominant-negative manner. Tamoxifen-induced, cardiac-specific Cx45 knockout mice showed sinus node dysfunction and atrial arrhythmia, recapitulating the intra-atrial disturbance. CONCLUSIONS: Altogether, the authors showed that Cx45 mutant p.R75H is responsible for a novel disease entity of progressive atrial conduction system defects associated with craniofacial and dentodigital malformation.
[Mh] Termos MeSH primário: Bloqueio Atrioventricular/etiologia
Conexinas/genética
DNA/genética
Deformidades Dentofaciais/complicações
Mutação
[Mh] Termos MeSH secundário: Adolescente
Adulto
Animais
Bloqueio Atrioventricular/genética
Bloqueio Atrioventricular/fisiopatologia
Criança
Pré-Escolar
Conexinas/metabolismo
Análise Mutacional de DNA
Deformidades Dentofaciais/genética
Deformidades Dentofaciais/metabolismo
Modelos Animais de Doenças
Progressão da Doença
Eletrocardiografia
Feminino
Seres Humanos
Masculino
Camundongos
Camundongos Transgênicos
Meia-Idade
Linhagem
Fenótipo
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Connexins); 0 (connexin 45); 9007-49-2 (DNA)
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170901
[Lr] Data última revisão:
170901
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:170715
[St] Status:MEDLINE


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[PMID]:28480846
[Au] Autor:Galich LV; Kuroedova V; Lakhtin Y; Galich LB; Moskalenko P
[Ad] Endereço:Medical Institute at Sumy State University; Higher State Educational Institution "Ukrainian Medical Dental Academy", Ukraine.
[Ti] Título:DEPENDENCE OF MORPHOMETRIC PARAMETERS OF THE DENTAL OCCLUSION ON THE TYPE OF THE LOWER JAW GROWTH IN CHILDREN WITH CLASS II1 DENTOFACIAL ANOMALIES WHO LINE IN THE NORTHERN UKRAINE.
[So] Source:Georgian Med News;(264):35-39, 2017 Mar.
[Is] ISSN:1512-0112
[Cp] País de publicação:Georgia (Republic)
[La] Idioma:eng
[Ab] Resumo:The aim of the work was to study the structure of dentofacial anomalies in children and adolescents in Sumy city and Sumy oblast, to identify dentoalveolar morphological peculiarities of the occlusion in 10-13 years old patients with class ІІ1 anomalies according to Angle's classification with different types of lower jaw bone growth. A retrospective analysis of 2236 outpatient dental cards of urban and rural patients with orthodontic pathology was conducted. Patients were divided into three age groups: 6-9 years old (early mixed occlusion) - 592 children; 10-13 years old (late mixed occlusion) - 1180 children; over 13 years old (permanent occlusion) - 464 persons; besides 76 patients with class ІІ1 anomalies according to Angle's classification aged 10-13 years were examined. To determine the type of lower jaw growth, the children underwent orthopantomographic examination, diagnostic models were made and biometric indicators were calculated to determine the severity of the morphological changes. It was established that anomalies of individual teeth and dental curve dominated in all age groups (71.24%). Among the occlusion anomalies, a large part falls to class ІІ anomalies according to Angle's classification (19.18%). A third of these patients have a neutral type of lower jaw growth (36.84±5.53%), horizontal and vertical types of growth reach 18.42±4.47% and 19.74±4.56%, respectively. The combination of neutral and vertical type of growth of the lower jaw occurs in 1.7 times more than the combination of neutral and horizontal. The most pronounced morphological changes were observed in the group of patients with a horizontal type of lower jaw growth. When planning treatment and prophylactic measures among patients of the orthodontic profile, it is necessary to take into account the peculiarities of both the prevalence of pathology in the region and the morphological changes of different severity in the dental curves of the jaws.
[Mh] Termos MeSH primário: Oclusão Dentária
Deformidades Dentofaciais/patologia
Mandíbula/crescimento & desenvolvimento
[Mh] Termos MeSH secundário: Adolescente
Criança
Deformidades Dentofaciais/fisiopatologia
Feminino
Seres Humanos
Masculino
Estudos Retrospectivos
Ucrânia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1708
[Cu] Atualização por classe:170808
[Lr] Data última revisão:
170808
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170509
[St] Status:MEDLINE


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[PMID]:28056044
[Au] Autor:Zhao YJ; Xiong YX; Wang Y
[Ad] Endereço:National Engineering Laboratory for Digital and Material Technology of Stomatology, Beijing, PR China.
[Ti] Título:Three-Dimensional Accuracy of Facial Scan for Facial Deformities in Clinics: A New Evaluation Method for Facial Scanner Accuracy.
[So] Source:PLoS One;12(1):e0169402, 2017.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:In this study, the practical accuracy (PA) of optical facial scanners for facial deformity patients in oral clinic was evaluated. Ten patients with a variety of facial deformities from oral clinical were included in the study. For each patient, a three-dimensional (3D) face model was acquired, via a high-accuracy industrial "line-laser" scanner (Faro), as the reference model and two test models were obtained, via a "stereophotography" (3dMD) and a "structured light" facial scanner (FaceScan) separately. Registration based on the iterative closest point (ICP) algorithm was executed to overlap the test models to reference models, and "3D error" as a new measurement indicator calculated by reverse engineering software (Geomagic Studio) was used to evaluate the 3D global and partial (upper, middle, and lower parts of face) PA of each facial scanner. The respective 3D accuracy of stereophotography and structured light facial scanners obtained for facial deformities was 0.58±0.11 mm and 0.57±0.07 mm. The 3D accuracy of different facial partitions was inconsistent; the middle face had the best performance. Although the PA of two facial scanners was lower than their nominal accuracy (NA), they all met the requirement for oral clinic use.
[Mh] Termos MeSH primário: Cefalometria/métodos
Deformidades Dentofaciais/diagnóstico por imagem
Face/anatomia & histologia
Imagem Tridimensional/normas
[Mh] Termos MeSH secundário: Algoritmos
Cabeça/anatomia & histologia
Seres Humanos
Software
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1708
[Cu] Atualização por classe:170828
[Lr] Data última revisão:
170828
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170106
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0169402


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[PMID]:27746257
[Au] Autor:Posnick JC; Choi E; Chavda A
[Ad] Endereço:Director, Posnick Center for Facial Plastic Surgery, Chevy Chase, MD; Clinical Professor, Department of Surgery and Pediatrics, Georgetown University, Washington, DC; Clinical Professor, Department of Orthodontics, University of Maryland School of Dentistry, Baltimore, MD; Adjunct Professor, Department of Oral and Maxillofacial Surgery, Howard University College of Dentistry, Washington, DC. Electronic address: jposnick@drposnick.com.
[Ti] Título:Surgical Site Infections Following Bimaxillary Orthognathic, Osseous Genioplasty, and Intranasal Surgery: A Retrospective Cohort Study.
[So] Source:J Oral Maxillofac Surg;75(3):584-595, 2017 Mar.
[Is] ISSN:1531-5053
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:PURPOSE: Frequency estimates of surgical site infection (SSI) after orthognathic surgery vary considerably. The purpose of this study was to determine the incidence and site of SSIs and associated risk factors after bimaxillary orthognathic, osseous genioplasty, and intranasal surgery. MATERIALS AND METHODS: The authors executed a retrospective cohort study of patients with a bimaxillary developmental dentofacial deformity (DFD) and symptomatic chronic obstructive nasal breathing. All patients underwent at a minimum Le Fort I osteotomy, bilateral sagittal ramus osteotomies (SROs), septoplasty, inferior turbinate reduction, and osseous genioplasty. The primary outcome variable studied was the incidence and site of SSI. Predictor variables were type and extent of prophylactic antibiotic used, demographic (age and gender), and anatomic (pattern of DFD, surgical site, and presence of third molar). RESULTS: Two hundred sixty-two patients met the inclusion criteria. Their average age at surgery was 25 years (range, 13 to 63 yr) and there were 134 female patients (51%). The major presenting patterns of DFD included long face (30%) and maxillary deficiency (25%). Forty percent of patients undergoing an SRO and 47% of those undergoing a Le Fort I osteotomy underwent simultaneous removal of a third molar. Ninety percent of patients received cefazolin or cephalexin antibiotics. Overall, 5 of 1,048 (0.5%) osteotomy sites sustained an infection, including 1 chin and 4 ramus SSIs. There were no delays in bone healing. Fixation hardware removal was not required in any patient who developed an infection. Two of the 25 patients (8%) given clindamycin prophylaxis developed an SSI, whereas 3 of 237 patients (1%) receiving cefazolin did. Three of the 4 patients who developed an SRO SSI underwent simultaneous removal of an erupted or partially erupted mandibular third molar (P < .05). CONCLUSIONS: In this study, the incidence of SSI was limited to 1% of patients who were given cefazolin or cephalexin extended for 5 days. The removal of an erupted or partially erupted mandibular third molar in conjunction with an SRO was associated with risk of SSI, but the incidence remains low.
[Mh] Termos MeSH primário: Deformidades Dentofaciais/cirurgia
Mentoplastia
Procedimentos Cirúrgicos Ortognáticos
Infecção da Ferida Cirúrgica/epidemiologia
[Mh] Termos MeSH secundário: Adolescente
Adulto
Antibioticoprofilaxia
Feminino
Seres Humanos
Incidência
Masculino
Osteotomia Maxilar
Meia-Idade
Septo Nasal/cirurgia
Osteotomia de Le Fort
Osteotomia Sagital do Ramo Mandibular
Estudos Retrospectivos
Conchas Nasais/cirurgia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1704
[Cu] Atualização por classe:170428
[Lr] Data última revisão:
170428
[Sb] Subgrupo de revista:AIM; D; IM
[Da] Data de entrada para processamento:161018
[St] Status:MEDLINE


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[PMID]:27720720
[Au] Autor:Goulart DR; Muñoz P; Cantín López MG; de Moraes M; Olate S
[Ad] Endereço:PhD Student, Division of Oral and Maxillofacial Surgery, Piracicaba Dental School, State University of Campinas, Piracicaba, SP, Brazil. Electronic address: douglasrgoulart@gmail.com.
[Ti] Título:Comparative Evaluation of Condylar Volume Between Patients With Unilateral Condylar Hyperplasia and Class III Dentofacial Deformity.
[So] Source:J Oral Maxillofac Surg;75(1):180-188, 2017 Jan.
[Is] ISSN:1531-5053
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:PURPOSE: To compare the condylar volume of patients with unilateral condylar hyperplasia (UCH) with that of patients with a Class III skeletal relation. MATERIALS AND METHODS: Twenty cone-beam computed tomograms of patients were analyzed. Images were divided into 2 groups: 10 from patients with transverse asymmetry of the face and 10 from patients with a Class III facial deformity. Patients' ages ranged from 15 to 30 years. Volumetric data were reconstructed using Dolphin 3D software (Dolphin Imaging & Management Solutions, Chatsworth, CA). This software measured the condylar volume above the deepest point of the sigmoid notch, the lower arch midline deviation, and the overjet. RESULTS: The condyle with hyperplasia exhibited the largest volume (1.97 ± 0.52 cm ) and a statistically significant difference compared with the contralateral condyle (χ = 14.30; P < .01). The Class III condyle exhibited relative symmetry of volume between the left and right sides. These condyles exhibited a larger volume compared with the non-hyperplastic condyles in the UCH group, with a statistically significant difference (χ = 6.22; P = .013; χ = 5.50; P = .019). CONCLUSIONS: Hyperplastic condyles were similar in volume to the condyles of patients with mandibular prognathism, suggesting that patients with a Class III skeletal relation could exhibit bilateral condylar hyperplasia.
[Mh] Termos MeSH primário: Deformidades Dentofaciais/patologia
Côndilo Mandibular/patologia
[Mh] Termos MeSH secundário: Adolescente
Adulto
Tomografia Computadorizada de Feixe Cônico
Deformidades Dentofaciais/complicações
Deformidades Dentofaciais/diagnóstico por imagem
Feminino
Seres Humanos
Hiperplasia
Masculino
Má Oclusão de Angle Classe III/complicações
Má Oclusão de Angle Classe III/diagnóstico por imagem
Má Oclusão de Angle Classe III/patologia
Côndilo Mandibular/anormalidades
Côndilo Mandibular/diagnóstico por imagem
Tamanho do Órgão
Adulto Jovem
[Pt] Tipo de publicação:COMPARATIVE STUDY; JOURNAL ARTICLE
[Em] Mês de entrada:1704
[Cu] Atualização por classe:170817
[Lr] Data última revisão:
170817
[Sb] Subgrupo de revista:AIM; D; IM
[Da] Data de entrada para processamento:161011
[St] Status:MEDLINE


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[PMID]:28005826
[Au] Autor:da Silva de Menezes JD; Moura LB; Martins RP; Hochuli-Vieira E
[Ad] Endereço:*Division of Oral and Maxillofacial Surgery, Department of Diagnosis and Surgery†Department of Orthodontics, Dental School at Araraquara-Unesp, Araraquara, Brazil.
[Ti] Título:Porous Polyethylene Implant as Aesthetic Complement in Orthognathic Surgery.
[So] Source:J Craniofac Surg;27(8):e790-e791, 2016 Nov.
[Is] ISSN:1536-3732
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Porous polyethylene implants have been used as an alternative in the treatment of patients with zygomatic and paranasal projections deficiency. These implants promote a facial rejuvenating effect due to the attenuation of the nasal and chin prominences. The advantages of porous polyethylene include biocompatibility, dimensional stability, easy adaptation and fixation, low complication rate, and its availability in different sizes and shapes. A 27-year-old woman presenting vertical deficiency associated with midface hypoplasia was treated with orthognathic surgery. Clockwise rotation and genioplasty were performed. In order to improve facial aesthetics, porous polyethylene implants were placed in the paranasal area, optimizing the facial contour with the correction of the midface projection.
[Mh] Termos MeSH primário: Deformidades Dentofaciais/cirurgia
Face/cirurgia
Procedimentos Cirúrgicos Ortognáticos/métodos
Polietileno
Próteses e Implantes
[Mh] Termos MeSH secundário: Adulto
Deformidades Dentofaciais/diagnóstico
Estética
Feminino
Seres Humanos
Porosidade
Desenho de Prótese
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Nm] Nome de substância:
9002-88-4 (Polyethylene)
[Em] Mês de entrada:1705
[Cu] Atualização por classe:170817
[Lr] Data última revisão:
170817
[Sb] Subgrupo de revista:D
[Da] Data de entrada para processamento:161223
[St] Status:MEDLINE
[do] DOI:10.1097/SCS.0000000000003131


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[PMID]:27689858
[Au] Autor:Owosho AA; Brady P; Wolden SL; Wexler LH; Antonescu CR; Huryn JM; Estilo CL
[Ad] Endereço:a Department of Surgery , Memorial Sloan Kettering Cancer Center , New York, New York , USA.
[Ti] Título:Long-term effect of chemotherapy-intensity-modulated radiation therapy (chemo-IMRT) on dentofacial development in head and neck rhabdomyosarcoma patients.
[So] Source:Pediatr Hematol Oncol;33(6):383-392, 2016 Sep.
[Is] ISSN:1521-0669
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Dentofacial developmental abnormalities have been reported in head and neck rhabdomyosarcoma (HNRMS) patients treated with conventional radiotherapy technique and chemotherapy. This current study investigates dentofacial long-term effects among HNRMS survivors managed with intensity-modulated radiotherapy (IMRT) and chemotherapy. In general, IMRT is a more effective 3D-conformal radiotherapy technique, which delivers high doses of radiation to the tumor target while minimizing doses received by the surrounding normal tissues. The medical records and radiographs of thirteen patients were reviewed to identify the following: 1. Facial asymmetry and jaw hypoplasia. 2. Effects on the dental tissue causing tooth agenesis/hypodontia, root agenesis/stunting/malformation, and/or enamel hypoplasia. 3. Trismus, hyposalivation/xerostomia. Seven patients presented with facial asymmetry and jaw hypoplasia, 9 patients presented with effects on the dental tissue [root agenesis/stunting/malformation (9), tooth agenesis/hypodontia (7) and enamel hypoplasia (3)] and 7 patients developed trismus and /or xerostomia. All patients with facial asymmetry and jaw hypoplasia also developed dental abnormalities. Patients with dentofacial developmental abnormalities were ≤7 years of age at treatment. Our study shows that dentofacial developmental abnormalities are still a burden in the era of IMRT and as prognosis of childhood malignancy improves and more patients survive, these late dentofacial sequelae among childhood cancer survivors will become more common. Dental oncologists should be integral members in the management of children with head and neck cancers.
[Mh] Termos MeSH primário: Quimiorradioterapia/efeitos adversos
Assimetria Facial
Neoplasias de Cabeça e Pescoço
Anormalidades Maxilomandibulares
Rabdomiossarcoma
[Mh] Termos MeSH secundário: Pré-Escolar
Deformidades Dentofaciais
Assimetria Facial/etiologia
Assimetria Facial/mortalidade
Assimetria Facial/prevenção & controle
Feminino
Neoplasias de Cabeça e Pescoço/mortalidade
Neoplasias de Cabeça e Pescoço/terapia
Seres Humanos
Lactente
Anormalidades Maxilomandibulares/etiologia
Anormalidades Maxilomandibulares/mortalidade
Anormalidades Maxilomandibulares/prevenção & controle
Masculino
Rabdomiossarcoma/mortalidade
Rabdomiossarcoma/terapia
Fatores de Tempo
[Pt] Tipo de publicação:CLINICAL TRIAL; JOURNAL ARTICLE
[Em] Mês de entrada:1703
[Cu] Atualização por classe:170930
[Lr] Data última revisão:
170930
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161001
[St] Status:MEDLINE


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[PMID]:27677685
[Au] Autor:Li Y; Hu Z; Ye B; Liu Y; Ren X; Zhu S
[Ad] Endereço:Associate Professor, State Key Laboratory of Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, China.
[Ti] Título:Combined Use of Facial Osteoplasty and Orthognathic Surgery for Treatment of Dentofacial Deformities.
[So] Source:J Oral Maxillofac Surg;74(12):2505.e1-2505.e12, 2016 Dec.
[Is] ISSN:1531-5053
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:PURPOSE: Orthognathic surgery is an efficient procedure for cosmetic and functional aims. However, when functional improvement is achieved by mandibular or maxillary operations, additional esthetic corrections may be imperative for some patients. This study aims to introduce our primary practice of simultaneous facial bone contouring and orthognathic surgery for esthetic reasons. PATIENTS AND METHODS: Ten patients with dentofacial deformities as well as a prominent angle, asymmetric deformities, or a high zygoma and zygomatic arch were recruited from West China Hospital of Stomatology, Sichuan University (Chengdu, China), between January 1, 2014, and July 31, 2015. Traditional orthognathic surgical procedures such as bilateral sagittal split osteotomy and Le Fort I osteotomy combined with facial osteoplasty including mandibular angle ostectomy, outer cortex ostectomy of the mandibular angle, and zygoma and zygomatic arch reduction were performed. Radiographs and medical photographs were taken before and after surgery to compare the effectiveness of the combined use of facial osteoplasty and orthognathic surgery. RESULTS: All patients had an uneventful postoperative recovery, with no signs of infection, jaw displacement, or osteonecrosis. Radiographs taken 1 week after surgery and pictures of the facial profile and occlusion taken 6 months after surgery showed satisfactory esthetic outcomes. All patients were satisfied with the functional and cosmetic results. CONCLUSIONS: This study indicated the clinical feasibility of simultaneous facial bone contouring and orthognathic surgery for the treatment of dentofacial deformities. Simultaneous facial bone contouring seems to be an alternative procedure in addition to conventional orthognathic surgery for cosmetic aims in certain patients.
[Mh] Termos MeSH primário: Deformidades Dentofaciais/cirurgia
Procedimentos Cirúrgicos Ortognáticos/métodos
Osteotomia de Le Fort/métodos
Osteotomia Sagital do Ramo Mandibular/métodos
[Mh] Termos MeSH secundário: Adulto
Estudos de Viabilidade
Feminino
Seguimentos
Seres Humanos
Masculino
Mandíbula/cirurgia
Resultado do Tratamento
Adulto Jovem
Zigoma/cirurgia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1705
[Cu] Atualização por classe:170817
[Lr] Data última revisão:
170817
[Sb] Subgrupo de revista:AIM; D; IM
[Da] Data de entrada para processamento:160929
[St] Status:MEDLINE


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[PMID]:27548833
[Au] Autor:On SW; Kim HJ; Kim J; Choi JW; Jung YW; Song SI
[Ad] Endereço:*Division of Oral and Maxillofacial Surgery, Department of Dentistry †Department of Otorhinolaryngology ‡Office of Biostatistics §Department of Radiology, Ajou University School of Medicine, Suwon, Republic of Korea.
[Ti] Título:Effect of Osteoporosis on Bone Density of Orthognathic Osteotomy Sites in Maxillofacial Region.
[So] Source:J Craniofac Surg;27(7):e678-e683, 2016 Oct.
[Is] ISSN:1536-3732
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:OBJECTIVES: The aims of this study were to investigate the availability of Hounsfield unit (HU) measurement of computed tomography (CT) in evaluating the bone density of certain sites by comparing bone density between CT and dual-energy x-ray absorptiometry (DEXA), and to evaluate the effects of osteoporosis on osteotomy sites in orthognathic surgery. METHODS: This retrospective study included 80 patients who had undergone both facial CT and DEXA at our hospital. We selected 7 regions of interest from among the osteotomy sites in bimaxillary orthognathic surgery. The patients were assigned to either the normal (control) group (n = 40) or the abnormal group (n = 40), and HU values were measured in each region of interest. RESULTS: There were statistically significant differences in the mean HU values between 2 groups at all the osteotomy sites in the maxilla and mandible, with the normal group showing higher values than the abnormal group (P < 0.05). In addition, there was a significant positive correlation between T-scores obtained with DEXA and the HU values on CT at the osteotomy sites (P < 0.01). Multiple regression analysis indicated that the abnormal group was more negatively associated with 6 osteotomy sites except for 1 maxillary area, as compared with the normal group. CONCLUSIONS: Measurement of HU values on CT can be valuable in assessing bone density of the maxilla and mandible. It is suggested that osteoporosis may affect bone density at the osteotomy sites in orthognathic surgery, and the preoperative measurement of HU values might be useful in predicting unfavorable fracture or the risks involved in such surgery.
[Mh] Termos MeSH primário: Densidade Óssea
Deformidades Dentofaciais/cirurgia
Mandíbula/diagnóstico por imagem
Maxila/diagnóstico por imagem
Procedimentos Cirúrgicos Ortognáticos/métodos
Osteoporose/complicações
Osteotomia/métodos
[Mh] Termos MeSH secundário: Absorciometria de Fóton
Adulto
Idoso
Idoso de 80 Anos ou mais
Deformidades Dentofaciais/complicações
Deformidades Dentofaciais/diagnóstico
Feminino
Seres Humanos
Masculino
Mandíbula/cirurgia
Maxila/cirurgia
Meia-Idade
Tomografia Computadorizada Multidetectores
Osteoporose/diagnóstico
Osteoporose/cirurgia
Estudos Retrospectivos
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1705
[Cu] Atualização por classe:170817
[Lr] Data última revisão:
170817
[Sb] Subgrupo de revista:D
[Da] Data de entrada para processamento:160823
[St] Status:MEDLINE


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[PMID]:27457766
[Au] Autor:Hanna R; Parker S
[Ad] Endereço:Oral Surgery Department, Dental Institute, King's College Hospital, Denmark Hill, London, SE5 9RS, UK. reem.hanna@nhs.net.
[Ti] Título:The advantages of carbon dioxide laser applications in paediatric oral surgery. A prospective cohort study.
[So] Source:Lasers Med Sci;31(8):1527-1536, 2016 Nov.
[Is] ISSN:1435-604X
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:The aim of this study is to evaluate and demonstrate the advantages of the carbon dioxide laser in paediatric oral surgery patients in terms of less post-operative complications, healing without scaring, functional benefits, positive patient perception and acceptance of the treatment. One hundred fit and healthy paediatric patients (aged 4-15 years) were recruited to undergo laser surgery for different soft tissue conditions. The outcome of these laser treatments was examined. The Wong-Baker Faces Pain Rating Scale was employed to evaluate the pain before, immediately after laser treatment in the clinic and 1 day after post-operatively at home. Post-operative complications and patients' perception and satisfaction were self-reported during a review telephone call the day after treatment. The patients were reviewed 2 weeks after surgery. Laser parameter was 1.62 W, measured by power meter, continuous wave mode with 50 % emission cycle. The beam spot size at the target tissue was 0.8 mm. The pain score pre-operative, during and immediately after laser treatment was rated 0. Whilst the pain score 1 day after surgery was rated between 0 and 2, the healing time was measured over 2 weeks. None of the patients reported post-operative complications after surgery. Patients' perception and acceptance were rated very good. Laser dentistry is a promising field in modern minimally invasive dentistry, which enables provision of better care for children and adolescents. In this cohort study, the use of the carbon dioxide laser therapy offers a desirable, acceptable and minimally invasive technique in the surgical management of soft tissues in paediatric oral surgery with minimal post-operative complications.
[Mh] Termos MeSH primário: Deformidades Dentofaciais/cirurgia
Lasers de Gás/uso terapêutico
Procedimentos Cirúrgicos Bucais/métodos
[Mh] Termos MeSH secundário: Adolescente
Criança
Pré-Escolar
Feminino
Seres Humanos
Terapia a Laser
Masculino
Procedimentos Cirúrgicos Bucais/efeitos adversos
Dor Pós-Operatória/epidemiologia
Período Pós-Operatório
Estudos Prospectivos
Resultado do Tratamento
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1612
[Cu] Atualização por classe:171013
[Lr] Data última revisão:
171013
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160727
[St] Status:MEDLINE



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