Base de dados : MEDLINE
Pesquisa : C06.267 [Categoria DeCS]
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  1 / 292 MEDLINE  
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[PMID]:28668860
[Au] Autor:Greene C; Nakakura EK; Ko AH
[Ad] Endereço:Division of Hematology/Oncology, Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, CA, U.S.A.
[Ti] Título:Gastrocutaneous Fistula in a Patient with Locally Recurrent MSI-High Colorectal Cancer: Local Complications Arising from Therapeutic Response to Immune Checkpoint Blockade.
[So] Source:Anticancer Res;37(7):3679-3684, 2017 07.
[Is] ISSN:1791-7530
[Cp] País de publicação:Greece
[La] Idioma:eng
[Ab] Resumo:Colorectal cancers with high microsatellite instability (MSI-H) have distinct clinical features in terms of their prognosis, recurrence patterns, and sensitivity to immunotherapeutic agents. We present the case of a woman with a left-sided MSI-H colon cancer who had repeated recurrences concentrated exclusively in the left upper quadrant of the abdomen, including gastric involvement. Despite multiple surgical resections, radiation, and several lines of chemotherapy, her disease eventually eroded through the chest wall. Treatment with an immune checkpoint inhibitor produced a rapid clinical response with significant tumor necrosis; however, this necessitated surgical debridement that ultimately led to a large gastrocutaneous fistula. This case highlights the importance of recognizing locoregional tumor-associated complications that may result from robust therapeutic responses to immuno-oncology drugs, which are increasingly being used in clinical practice today.
[Mh] Termos MeSH primário: Neoplasias Colorretais/complicações
Neoplasias Colorretais/terapia
Fístula do Sistema Digestório/etiologia
Imunoterapia/efeitos adversos
Recidiva Local de Neoplasia/patologia
[Mh] Termos MeSH secundário: Neoplasias Colorretais/patologia
Fístula do Sistema Digestório/patologia
Feminino
Seres Humanos
Instabilidade de Microssatélites
Meia-Idade
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Em] Mês de entrada:1708
[Cu] Atualização por classe:170906
[Lr] Data última revisão:
170906
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170703
[St] Status:MEDLINE


  2 / 292 MEDLINE  
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[PMID]:28440519
[Au] Autor:Wu H; Zhong M; Zhou D; Shi C; Jiao H; Wu W; Chang X; Cang J; Bian H
[Ad] Endereço:Department of General Surgery, Multidisciplinary Team of Bariatric and Metabolic Surgery from Zhongshan Hospital, Fudan University, Shanghai 200032, China. wu.haifu@zs-hospital.sh.cn.
[Ti] Título:[Prevention, diagnosis and treatment of perioperative complications of bariatric and metabolic surgery].
[So] Source:Zhonghua Wei Chang Wai Ke Za Zhi;20(4):393-397, 2017 Apr 25.
[Is] ISSN:1671-0274
[Cp] País de publicação:China
[La] Idioma:chi
[Ab] Resumo:Surgical operation in treating obesity and type 2 diabetes is popularizing rapidly in China. Correct prevention and recognition of perioperation-related operative complications is the premise of ensuring surgical safety. Familiar complications of the operation include deep venous thrombosis, pulmonary artery embolism, anastomotic bleeding, anastomotic fistula and marginal ulcer. The prevention of deep venous thrombosis is better than treatment. The concrete measures contain physical prophylaxis (graduated compression stocking and intermittent pneumatic compression leg sleeves) and drug prophylaxis (unfractionated heparin and low molecular heparin), and the treatment is mainly thrombolysis or operative thrombectomy. The treatment of pulmonary artery embolism includes remittance of pulmonary arterial hypertension, anticoagulation, thrombolysis, operative thrombectomy, interventional therapy and extracorporeal membrane oxygenation (ECMO). Hemorrhage is a rarely occurred but relatively serious complication after bariatric surgery. The primary cause of anastomotic bleeding after laparoscopic gastric bypass is incomplete hemostasis or weak laparoscopic repair. The common bleeding site in laparoscopic sleeve gastrectomy is gastric stump and close to partes pylorica, and the bleeding may be induced by malformation and weak repair technique. Patients with hemodynamic instability caused by active bleeding or excessive bleeding should timely received surgical treatment. Anastomotic fistula in gastric bypass can be divided into gastrointestinal anastomotic fistula and jejunum-jejunum anastomotic fistula. The treatment of postoperative anastomotic fistula should vary with each individual, and conservative treatment or operative treatment should be adopted. Anastomotic stenosis is mainly related to the operative techniques. Stenosis after sleeve gastrectomy often occurs in gastric angle, and the treatment methods include balloon dilatation and stent implantation, and surgical treatment should be performed when necessary. Marginal ulcer after gastric bypass is a kind of peptic ulcer occurring close to small intestine mucosa in the junction point of stomach and jejunum. Ulcer will also occur in the vestige stomach after laparoscopic sleeve gastrectomy, and the occurrence site locates mostly in the gastric antrum incisal margin. Preoperative anti-HP (helicobacter pylorus) therapy and postoperative continuous administration of proton pump inhibitor (PPI) for six months is the main means to prevent and treat marginal ulcer. For patients on whom conservative treatment is invalid, endoscopic repair or surgical repair should be considered. Different surgical procedures will generate different related operative complications. Fully understanding and effectively dealing with the complications of various surgical procedures through multidisciplinary cooperation is a guarantee for successful operation.
[Mh] Termos MeSH primário: Anastomose Cirúrgica/efeitos adversos
Cirurgia Bariátrica/efeitos adversos
Gastrectomia/efeitos adversos
Derivação Gástrica/efeitos adversos
Hemorragia Gastrointestinal/prevenção & controle
Hemorragia Gastrointestinal/cirurgia
Laparoscopia/efeitos adversos
Complicações Pós-Operatórias/diagnóstico
Complicações Pós-Operatórias/prevenção & controle
Complicações Pós-Operatórias/terapia
Embolia Pulmonar/terapia
Trombose Venosa/prevenção & controle
Trombose Venosa/terapia
[Mh] Termos MeSH secundário: Anticoagulantes/uso terapêutico
Cateterismo
China
Tratamento Conservador
Constrição Patológica/etiologia
Constrição Patológica/terapia
Fístula do Sistema Digestório/etiologia
Fístula do Sistema Digestório/terapia
Endoscopia Gastrointestinal/métodos
Oxigenação por Membrana Extracorpórea
Mucosa Gástrica/patologia
Coto Gástrico/fisiopatologia
Coto Gástrico/cirurgia
Hemorragia Gastrointestinal/etiologia
Hemostasia Cirúrgica/efeitos adversos
Hemostasia Cirúrgica/métodos
Técnicas Hemostáticas
Heparina/uso terapêutico
Seres Humanos
Dispositivos de Compressão Pneumática Intermitente
Intestino Delgado/patologia
Margens de Excisão
Úlcera Péptica/etiologia
Úlcera Péptica/terapia
Embolia Pulmonar/etiologia
Stents
Meias de Compressão
Trombectomia
Terapia Trombolítica
Trombose Venosa/etiologia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Anticoagulants); 9005-49-6 (Heparin)
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170908
[Lr] Data última revisão:
170908
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170426
[St] Status:MEDLINE


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[PMID]:28226350
[Au] Autor:Zhang Y; Zhou P
[Ti] Título:[Value of endoscopy application in the management of complications after radical gastrectomy for gastric cancer].
[So] Source:Zhonghua Wei Chang Wai Ke Za Zhi;20(2):160-165, 2017 Feb 25.
[Is] ISSN:1671-0274
[Cp] País de publicação:China
[La] Idioma:chi
[Ab] Resumo:Endoscopy plays an important role in the diagnosis and treatment of postoperative complications of gastric cancer. Endoscopic intervention can avoid the second operation and has attracted wide attention. Early gastric anastomotic bleeding after gastrectomy is the most common. With the development of technology, emergency endoscopy and endoscopic hemostasis provide a new treatment approach. According to the specific circumstances, endoscopists can choose metal clamp to stop bleeding, electrocoagulation hemostasis, local injection of epinephrine or sclerotherapy agents, and spraying specific hemostatic agents. Anastomotic fistula is a serious postoperative complication. In addition to endoscopically placing the small intestine nutrition tube for early enteral nutrition support treatment, endoscopic treatment, including stent, metal clip, OTSC, and Over-stitch suture system, can be chosen to close fistula. For anastomotic obstruction or stricture, endoscopic balloon or probe expansion and stent placement can be chosen. For esophageal anastomotic intractable obstruction after gastroesophageal surgery, radial incision of obstruction by the hook knife or IT knife, a new method named ERI, is a good choice. Bile leakage caused by bile duct injury can be treated by placing the stent or nasal bile duct. In addition, endoscopic methods are widely used as follows: abdominal abscess can be treated by the direct intervention under endoscopy; adhesive ileus can be treated by placing the catheter under the guidance of endoscopy to attract pressure; alkaline reflux gastritis can be rapidly diagnosed by endoscopy; gastric outlet obstruction mainly caused by cancer recurrence can be relieved by metal stent placement and the combination of endoscopy and X-ray can increase success rate; pyloric dysfunction and spasm caused by the vagus nerve injury during proximal gastrectomy can be treated by endoscopic pyloromyotomy, a new method named G-POEM, and the short-term outcomes are significant. Endoscopic submucosal dissection (ESD) allows complete resection of residual gastric precancerous lesions, however it should be performed by the experienced endoscopists.
[Mh] Termos MeSH primário: Anastomose Cirúrgica/efeitos adversos
Endoscopia Gastrointestinal/métodos
Gastrectomia/efeitos adversos
Complicações Pós-Operatórias/diagnóstico
Complicações Pós-Operatórias/terapia
Neoplasias Gástricas/complicações
Neoplasias Gástricas/cirurgia
[Mh] Termos MeSH secundário: Ductos Biliares/lesões
Constrição Patológica/etiologia
Constrição Patológica/terapia
Fístula do Sistema Digestório/etiologia
Fístula do Sistema Digestório/terapia
Refluxo Duodenogástrico/diagnóstico por imagem
Refluxo Duodenogástrico/etiologia
Nutrição Enteral/instrumentação
Nutrição Enteral/métodos
Feminino
Obstrução da Saída Gástrica/cirurgia
Gastrite/diagnóstico
Hemorragia Gastrointestinal/etiologia
Hemorragia Gastrointestinal/terapia
Hemostase Endoscópica/métodos
Hemostáticos/administração & dosagem
Hemostáticos/uso terapêutico
Seres Humanos
Masculino
Recidiva Local de Neoplasia/cirurgia
Lesões Pré-Cancerosas/cirurgia
Piloro/inervação
Piloro/fisiopatologia
Piloro/cirurgia
Stents
Resultado do Tratamento
Traumatismos do Nervo Vago/etiologia
Traumatismos do Nervo Vago/cirurgia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Hemostatics)
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170908
[Lr] Data última revisão:
170908
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170223
[St] Status:MEDLINE


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[PMID]:28193160
[Au] Autor:Hua Z; Su Y; Huang X; Zhang K; Yin Z; Wang X; Liu P
[Ad] Endereço:Department of Hepatobiliary Surgery, Zhongshan Hospital of Xiamen University, Hubing South Road, Xiamen, Fujian, China.
[Ti] Título:Analysis of risk factors related to gastrointestinal fistula in patients with severe acute pancreatitis: a retrospective study of 344 cases in a single Chinese center.
[So] Source:BMC Gastroenterol;17(1):29, 2017 Feb 14.
[Is] ISSN:1471-230X
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Gastrointestinal fistula (GIF) in severe acute pancreatitis (SAP) is considered as a sparse episode and studied sporadically in the literature. There is paucity of data on the prediction of the effect on risk of GIF in patient with SAP. This study was aimed to investigate risk factors related to GIF in the development of SAP. METHODS: The clinical data of 344 patients with SAP from 2011 to 2016 were reviewed retrospectively. All patients were divided into the GIF group and the non-GIF group, and their data analyzed with respect to 15 parameters were applied to explore potential risk factors for GIF in patients with SAP. RESULTS: Of the 344 eligible patients, 52 (15.12%) progressed to GIF. Only occurrence of infected pancreatic and extra-pancreatic necrosis (IPN) (P = 0.004, OR = 3.012) and modified CT severity index (MCTSI) (P = 0.033, OR = 1.183) were proved to be independent risk factors for GIF in patients with SAP, and blood type B (P = 0.048, OR = 2.096, 95% CI: 0.748-3.562) indicated weaker association of risk factor for GIF. The early (48-72 h after admission) enteral nutrition (EEN) (P = 0.016, OR = 0.267) acted as a protective factor. CONCLUSIONS: Occurrence of IPN and high MCTSI are independent risk factors for the development of GIF in patients with SAP, blood type B reveals a potential correlation with GIF in patients with SAP. EEN is helpful to prevent the progression of GIF secondary to SAP.
[Mh] Termos MeSH primário: Sistema do Grupo Sanguíneo ABO
Fístula do Sistema Digestório/sangue
Fístula do Sistema Digestório/etiologia
Pâncreas/patologia
Pancreatite/complicações
[Mh] Termos MeSH secundário: Doença Aguda
Adulto
Idoso
China
Nutrição Enteral
Feminino
Seres Humanos
Masculino
Meia-Idade
Necrose
Fatores de Proteção
Estudos Retrospectivos
Fatores de Risco
Índice de Gravidade de Doença
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (ABO Blood-Group System)
[Em] Mês de entrada:1702
[Cu] Atualização por classe:170228
[Lr] Data última revisão:
170228
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170215
[St] Status:MEDLINE
[do] DOI:10.1186/s12876-017-0587-8


  5 / 292 MEDLINE  
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[PMID]:28105625
[Au] Autor:Wang G; Wang Z; Wu X; Diao Y; Zhao Y; Ren J; Li J
[Ti] Título:[Efficacy of over-the-scope clip for gastrointestinal fistula].
[So] Source:Zhonghua Wei Chang Wai Ke Za Zhi;20(1):79-83, 2017 Jan 25.
[Is] ISSN:1671-0274
[Cp] País de publicação:China
[La] Idioma:chi
[Ab] Resumo:OBJECTIVE: To explore the efficacy of over-the-scope clip (OTSC) in the treatment of gastrointestinal fistula. METHODS: Clinical data of 12 gastrointestinal fistula patients, including 3 internal fistula and 9 external fistula treated with OTSC in our institute from March 2015 to May 2016 were retrospectively analyzed. OTSC was performed when pus was drained thoroughly and intra-abdominal infection around gastrointestinal fistula was controlled, and each patient received one clip to close fistula. RESULTS: There were 6 female and 6 male patients with mean age of (50.1±12.6) years. The successful rate of endoscopic closure was 100% without complications including bleeding and intestinal obstruction during and after OTSC treatment. According to comprehensive evaluation, including drainage without digestive juices, no recurrence of intra-abdominal infection, no overflow of contrast medium during digestive tract radiography, and CT examination without intra-abdominal abscess, clinical gastrointestinal fistula closure was 91.7%(11/12). There was no recurrence of gastrointestinal fistula during 3 months of follow-up in 11 patients. In the remaining 1 case, the gastric fistula after laparoscopic sleeve gastrectomy recurred one week after OTSC treatment because of intra-abdominal infection surrounding fistula, and was cured by surgery finally. CONCLUSION: The endoscopic closure treatment of OTSC for gastrointestinal fistula is successful and effective, and control of intra-abdominal infection around fistula with adequate drainage is the key point.
[Mh] Termos MeSH primário: Fístula do Sistema Digestório/cirurgia
Endoscopia Gastrointestinal/instrumentação
Endoscopia Gastrointestinal/métodos
Infecções Intra-Abdominais/terapia
Dispositivos de Fixação Cirúrgica
[Mh] Termos MeSH secundário: Adulto
Fístula do Sistema Digestório/complicações
Fístula do Sistema Digestório/tratamento farmacológico
Drenagem
Feminino
Seres Humanos
Infecções Intra-Abdominais/etiologia
Masculino
Meia-Idade
Recidiva
Estudos Retrospectivos
Supuração/terapia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170908
[Lr] Data última revisão:
170908
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170121
[St] Status:MEDLINE


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[PMID]:28105624
[Au] Autor:Gao B; Huang Q; Dong J
[Ad] Endereço:Department of General Surgery, The First Hospital of Yulin, Yulin 719000, China.
[Ti] Título:[Clinical research of delta-shaped anastomosis technology in laparoscopic distal gastrectomy and digestive tract reconstruction].
[So] Source:Zhonghua Wei Chang Wai Ke Za Zhi;20(1):73-78, 2017 Jan 25.
[Is] ISSN:1671-0274
[Cp] País de publicação:China
[La] Idioma:chi
[Ab] Resumo:OBJECTIVE: To evaluate the feasibility and safety of the delta-shaped anastomosis in laparoscopic distal gastrectomy and digestive tract reconstruction. METHODS: Clinical data of 34 gastric cancer patients undergoing laparoscopic distal gastrectomy with the delta-shaped anastomosis for digestive tract reconstruction (delta-shaped group) and 83 gastric cancer patients undergoing laparoscopic distal gastrectomy with Billroth I( for digestive tract reconstruction (Billroth group) by same surgeon team from July 2013 to July 2015 at the Department of Digestive Surgery, Affiliated Tumor Hospital of Shanxi Medical University were retrospectively analyzed. Data of two groups were compared. RESULT: Age, gender, tumor stage were not significantly different between the two groups(all P>0.05). Operation time of the first 15 cases in delta-shaped group was longer than that in Billroth group [(254.7±35.4) min vs. (177.8±33.0) min, t=11.190, P=0.000], while after above 15 cases, the operation time of delta-shaped group was significantly shorter than that of Billroth group [(142.1±14.6) min vs. (177.8±33.0) min, t=-4.109, P=0.001]. Delta-shaped group had less blood loss during operation [(87.1±36.7) ml vs. (194.0±55.1) ml, t=-10.268, P=0.000], and shorter length of incision [(4.1±0.4) cm vs. (6.1±1.0) cm, t=-10.331, P=0.000] than Billroth group. Compared with Billroth group, delta-shaped group presented faster postoperative bowel function return [(2.8±0.6) d vs. (3.3±0.5) d, t=-3.755, P=0.000], earlier liquid food intake [(7.4±1.5) d vs. (8.1±1.7) d, t=-4.135, P=0.000], earlier ambulation [(4.0±1.6) d vs. (6.8±1.4) d, t=-7.197, P=0.000] and shorter postoperative hospital stay [(12.6±1.9) d vs.(13.6±2.0) d, t=-20.149, P=0.000]. Morbidity of postoperative complication was 5.9%(2/34) in delta-shaped group, including anastomotic fistula in 1 case and incision infection in 1 case, and 6.0%(5/83) in Billroth group, including anastomotic fistula, incision infection, anastomotic stricture and dumping syndrome, without significant difference(P>0.05). Difference value of total protein and albumin between pre-operation and post-operation, and average decreased value of total protein, albumin, body weight between pre-operation and postoperative 6-month were not significantly different between two groups(all P>0.05). As for patients with BMI > 25 kg/m , compared to Billroth group, delta-shaped group presented less blood loss during operation [(94.1±36.7) ml vs. (203.0±55.1) ml, t=-10.268, P=0.000], lower injective dosage of postoperative analgesics [(1.9±1.1) ampule vs.(3.3±2.0) ampule, t=-2.188, P=0.032], faster intestinal recovery [(2.9±0.7) d vs. (3.2±0.9) d, t=-3.755, P=0.009], shorter hospital stay [(10.5±1.2) d vs. (11.7±1.5) d, t=-2.026, P=0.004], and lower morbidity of postoperative complication [7.1%(1/14) vs. 13.6%(3/22), χ =4.066, P=0.031]. CONCLUSION: In laparoscopic distal gastrectomy and digestive tract reconstruction, the delta-shaped anastomosis is safe and feasible, especially suitable for obese patients.
[Mh] Termos MeSH primário: Anastomose Cirúrgica/efeitos adversos
Anastomose Cirúrgica/métodos
Gastroenterostomia/efeitos adversos
Gastroenterostomia/métodos
[Mh] Termos MeSH secundário: Perda Sanguínea Cirúrgica/estatística & dados numéricos
Pesquisa Comparativa da Efetividade
Constrição Patológica/epidemiologia
Constrição Patológica/etiologia
Defecação
Fístula do Sistema Digestório/epidemiologia
Fístula do Sistema Digestório/etiologia
Ingestão de Líquidos
Síndrome de Esvaziamento Rápido/epidemiologia
Síndrome de Esvaziamento Rápido/etiologia
Feminino
Gastrectomia/efeitos adversos
Gastrectomia/métodos
Seres Humanos
Laparoscopia/efeitos adversos
Laparoscopia/métodos
Tempo de Internação
Masculino
Duração da Cirurgia
Complicações Pós-Operatórias/epidemiologia
Período Pós-Operatório
Recuperação de Função Fisiológica
Estudos Retrospectivos
Neoplasias Gástricas/cirurgia
Ferida Cirúrgica
Infecção da Ferida Cirúrgica/epidemiologia
Resultado do Tratamento
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170908
[Lr] Data última revisão:
170908
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170121
[St] Status:MEDLINE


  7 / 292 MEDLINE  
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[PMID]:27819638
[Au] Autor:Marincas AM; Prunoiu VM; Cirimbei C; Buzatu R; Corniciuc R; Sersea C; Bratucu E; -
[Ti] Título:Digestive Decompression to Prevent Digestive Fistulas After Gastric Neoplasm Resection.
[So] Source:Chirurgia (Bucur);111(5):400-406, 2016 Sept-Oct.
[Is] ISSN:1221-9118
[Cp] País de publicação:Romania
[La] Idioma:eng
[Ab] Resumo:The risk of digestive fistula in patients operated for gastric neoplasm is increased due to biological imbalances generated by the cancer's progression, by diagnosis in advanced stages, and by the scale of intervention. Under these circumstances the use of some technical means to protect digestive sutures in these patients is useful. AIM: To analyse the efficiency of technical means to protect the digestive sutures in patients operated in various stages of development of gastric cancer. Material and We conducted a retrospective study on a group of 130 patients operated for gastric cancer in the 1st General Surgery and Oncology Clinic of the Bucharest Institute of Oncology, between 2010-2014. 38.46% of the patients in the study group presented stage IV cancer with multiple complications and biological imbalances. 52 total gastrectomies and 40 gastric resections were carried out, while in 34 patients palliative "tumour excisions" or other types of palliative surgery were performed. In 15 of the cases with gastric resection a duodenal decompression probe was used, while in 13 of the patients with total gastrectomy an oeso-jejunal aspiration probe together with an oeso-jejunal feeding probe were used as additional technical measures to prevent fistula formation. The incidence of duodenal stump fistula was 7.69%, that of oeso-jejunal anastomosis fistula was 2.3%, with an overall mortality of 3.07% and that of gastro-jejunal anastomosis fistula was 0.76%. CONCLUSION: Given the risk of fistula development in patients with gastric cancer, as well as the increased risk in advanced stages of cancer development, we consider that the use of technical means of protection of digestive sutures is beneficial and opportune, lowering the incidence of fistulas, reducing their output, pathophysiological effects, and mortality.
[Mh] Termos MeSH primário: Descompressão Cirúrgica
Fístula do Sistema Digestório/prevenção & controle
Gastrectomia
Neoplasias Gástricas/patologia
Neoplasias Gástricas/cirurgia
[Mh] Termos MeSH secundário: Anastomose Cirúrgica/efeitos adversos
Descompressão Cirúrgica/métodos
Fístula do Sistema Digestório/etiologia
Gastrectomia/efeitos adversos
Fístula Gástrica/prevenção & controle
Seres Humanos
Incidência
Fístula Intestinal/prevenção & controle
Estadiamento de Neoplasias
Estudos Retrospectivos
Romênia/epidemiologia
Neoplasias Gástricas/mortalidade
Resultado do Tratamento
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1702
[Cu] Atualização por classe:170222
[Lr] Data última revisão:
170222
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161108
[St] Status:MEDLINE


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[PMID]:27661050
[Au] Autor:Awotar GK; Luo F; Zhao Z; Guan G; Ning S; Ren J; Liu Y; Wang G; Liu P
[Ad] Endereço:aDepartment of General Surgery, The Second Affiliated Hospital of Dalian Medical University, Dalian City, Liaoning Province, 116023, P.R. China bThe First Affiliated Hospital Collaborative Innovation Center of Oncology-Institute of Cancer Stem Cell, Dalian Medical University, Dalian City, Liaoning Province, P.R. China.
[Ti] Título:Splenic abscess owing to cancer at the splenic flexure: A case report and comprehensive review.
[So] Source:Medicine (Baltimore);95(38):e4941, 2016 Sep.
[Is] ISSN:1536-5964
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: The cancer of the splenic flexure of the colon is a rare medical entity with severe morbidity because of its insidious onset. METHODS: We present the case of a 59-year-old male patient with dull left upper quadrant pain, leukocytosis, and anemia. A splenic abscess described as an air-fluid level with splenocolic fistula was found on CT scan imaging. Surgery was done for splenic pus drainage. He was again admitted 2 months later for intestinal obstruction. RESULTS: An exploratory laparotomy showed multiple hard, gray liver nodules as well as a hard mass in the small bowel. Owing to extensive adhesions and a late stage of cancer involvement, the splenic flexure tumor was not resected. A loop transverse colostomy was done and a Coloplast Colostomy bag placed. We also reviewed the literature-linking colon cancer and splenic abscess with specific attention to the carcinoma of the splenic flexure. As the latter invades through the spleen matter, there is the creation of a splenocolic fistula, which allows the migration of normal gut flora into the spleen. This leads to the formation of the splenic abscess. CONCLUSION: This is the 13 case report pertaining to invading colonic cancer causing a splenic abscess. Although the treatment for splenic abscesses is shifting from splenectomy to image-guided percutaneous pus drainage, the few reported cases make the proper management of such complication still unclear.
[Mh] Termos MeSH primário: Abscesso/etiologia
Neoplasias do Colo/complicações
Enterobacter cloacae/isolamento & purificação
Infecções por Enterobacteriaceae/etiologia
Esplenopatias/etiologia
[Mh] Termos MeSH secundário: Abscesso/microbiologia
Abscesso/cirurgia
Neoplasias do Colo/cirurgia
Fístula do Sistema Digestório/etiologia
Fístula do Sistema Digestório/cirurgia
Drenagem/métodos
Infecções por Enterobacteriaceae/microbiologia
Infecções por Enterobacteriaceae/cirurgia
Seres Humanos
Obstrução Intestinal/complicações
Obstrução Intestinal/cirurgia
Laparotomia
Masculino
Meia-Idade
Baço/patologia
Esplenopatias/microbiologia
Esplenopatias/cirurgia
Tomografia Computadorizada por Raios X
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE; REVIEW
[Em] Mês de entrada:1702
[Cu] Atualização por classe:170223
[Lr] Data última revisão:
170223
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:160924
[St] Status:MEDLINE
[do] DOI:10.1097/MD.0000000000004941


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[PMID]:27427946
[Au] Autor:Wein S; Beyer B; Gohlke A; Blank R; Metges CC; Wolffram S
[Ad] Endereço:Institute of Animal Nutrition & Physiology, Christian-Albrechts-University of Kiel, Kiel, Germany.
[Ti] Título:Systemic Absorption of Catechins after Intraruminal or Intraduodenal Application of a Green Tea Extract in Cows.
[So] Source:PLoS One;11(7):e0159428, 2016.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Green tea catechins have various potential health benefits in humans including anti-inflammatory, anti-oxidative and hepato-protective effects. If present in the circulation, they might have similar effects in ruminants, which are exposed to oxidative stress and fatty liver disease such as dairy cows during the periparturient phase. However, the bioavailability of a substance is a prerequisite for any post absorptive effect in vivo. This study aimed to investigate the appearance of catechins from a green tea extract (GTE) in cattle plasma after intraruminal and intraduodenal administration because absorption is of major importance regarding the bioavailability of catechins. The studies were performed in 5 rumen-fistulated non-lactating heifers and 6 duodenally fistulated lactating dairy cows, respectively, equipped with indwelling catheters placed in a jugular vein. The GTE was applied intraruminally (10 and 50 mg/kg BW, heifers) or duodenally (10, 20 and 30 mg/kg BW, dairy cows) in a cross-over design with a 2 d washout period between different dosages. Blood samples were drawn following the GTE administration at various pre-defined time intervals. The concentration of the major GTE catechins (gallocatechin, epigallocatechin, catechin, epicatechin, epigallocatechin-gallate, epicatechin-gallate) in plasma samples were analysed by HPLC with electrochemical detection. Irrespective of the dose, almost none of the catechins originally contained in the GTE were detected in plasma samples after intraruminal application. In contrast, intraduodenal administration of GTE resulted in increased plasma concentrations of epicatechin, epigallocatechin, epigallocatechin gallate in a dose-dependent manner. Thus, we can conclude that intraruminally or orally administered catechins are intensively metabolized by ruminal microorganisms.
[Mh] Termos MeSH primário: Catequina/análogos & derivados
Catequina/farmacocinética
Chá/química
[Mh] Termos MeSH secundário: Animais
Disponibilidade Biológica
Cateteres de Demora
Bovinos
Cromatografia Líquida de Alta Pressão
Fístula do Sistema Digestório
Duodeno/metabolismo
Feminino
Absorção Gastrointestinal/fisiologia
Veias Jugulares
Extratos Vegetais/química
Extratos Vegetais/farmacocinética
Rúmen/metabolismo
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Plant Extracts); 0 (Tea); 7Z197MG6QL (gallocatechol); 8R1V1STN48 (Catechin); 92587OVD8Z (epicatechin gallate); BQM438CTEL (epigallocatechin gallate)
[Em] Mês de entrada:1707
[Cu] Atualização por classe:170719
[Lr] Data última revisão:
170719
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160719
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0159428


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[PMID]:27372035
[Au] Autor:Prevot F; Browet F; Mauvais F
[Ad] Endereço:Service de chirurgie digestive, centre hospitalier universitaire d'Amiens, 80054 Amiens, France; Service de chirurgie viscérale et digestive, centre hospitalier de Beauvais, avenue Léon-Blum, BP 40319, 60021 Beauvais cedex, France.
[Ti] Título:Pyopneumothorax and peritonitis due to perforated duodenal ulcer and associated pleuroperitoneal communication.
[So] Source:J Visc Surg;153(4):311-3, 2016 Aug.
[Is] ISSN:1878-7886
[Cp] País de publicação:France
[La] Idioma:eng
[Ab] Resumo:Pleuroperitoneal communication is an anatomic entity that is typically asymptomatic but sometimes responsible for hydrothorax. This pleural manifestation can be explained by progressive transdiaphragmatic passage of intra-abdominal fluid because of abdominal hyperpressure. The object of this report is to present a hitherto unreported association of concomitant pleural effusion and acute infectious abdominal disease, due to perforated duodenal ulcer. This underscores that pleural effusion associated with acute abdominal pain may reveal the existence of a communication of this type, and requires surgical management.
[Mh] Termos MeSH primário: Fístula do Sistema Digestório/diagnóstico
Úlcera Duodenal/diagnóstico
Úlcera Péptica Perfurada/diagnóstico
Peritonite/etiologia
Derrame Pleural/etiologia
Pneumotórax/etiologia
Fístula do Sistema Respiratório/diagnóstico
[Mh] Termos MeSH secundário: Idoso
Fístula do Sistema Digestório/complicações
Úlcera Duodenal/complicações
Evolução Fatal
Feminino
Seres Humanos
Úlcera Péptica Perfurada/complicações
Peritonite/diagnóstico
Derrame Pleural/diagnóstico
Pneumotórax/diagnóstico
Fístula do Sistema Respiratório/complicações
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Em] Mês de entrada:1707
[Cu] Atualização por classe:170719
[Lr] Data última revisão:
170719
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160704
[St] Status:MEDLINE



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