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[PMID]:29186268
[Au] Autor:Camargo CC; D'Elia MPB; Miot HA
[Ad] Endereço:Department of Tropical Disesases and Imagery Diagnostics, Botucatu School of Medicine, Universidade Estadual Paulista "Júlio de Mesquita Filho" (FMB-Unesp) - Botucatu (SP) Brazil.
[Ti] Título:Quality of life in men diagnosed with anogenital warts.
[So] Source:An Bras Dermatol;92(3):427-429, 2017 May-Jun.
[Is] ISSN:1806-4841
[Cp] País de publicação:Brazil
[La] Idioma:eng
[Ab] Resumo:Anogenital warts are a worldwide public health problem. They consist of epithelial proliferations caused by HPV, whose transmission occurs mainly through sexual intercourse. In this study, we evaluated their impact on the quality of life of adult males. We interviewed 88 men in an outpatient clinic for sexually transmitted diseases at a Brazilian public institution, using the DLQI-BRA questionnaire. Most patients (81%) presented mild or no impairment of quality of life. The main dimensions affected were sex life, symptoms, and embarrassment. The low impact on quality of life may well justify the delay in seeking medical treatment, favoring the spread of the disease.
[Mh] Termos MeSH primário: Doenças do Ânus/psicologia
Condiloma Acuminado/psicologia
Qualidade de Vida/psicologia
[Mh] Termos MeSH secundário: Adulto
Instituições de Assistência Ambulatorial
Seres Humanos
Masculino
Fatores Socioeconômicos
Inquéritos e Questionários
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1801
[Cu] Atualização por classe:180131
[Lr] Data última revisão:
180131
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171130
[St] Status:MEDLINE


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[PMID]:28470702
[Au] Autor:Xu R; Tan KK; Chong CS
[Ad] Endereço:Division of Colorectal Surgery, University Surgical Cluster, National University Hospital, National University Health System, Singapore.
[Ti] Título:Response to Re: Bacteriological study in perianal abscess is not useful and not cost-effective.
[So] Source:ANZ J Surg;87(5):421, 2017 05.
[Is] ISSN:1445-2197
[Cp] País de publicação:Australia
[La] Idioma:eng
[Mh] Termos MeSH primário: Abscesso
Doenças do Ânus
[Mh] Termos MeSH secundário: Análise Custo-Benefício
Seres Humanos
Fístula Retal
[Pt] Tipo de publicação:LETTER; COMMENT
[Em] Mês de entrada:1801
[Cu] Atualização por classe:180131
[Lr] Data última revisão:
180131
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170505
[St] Status:MEDLINE
[do] DOI:10.1111/ans.13972


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[PMID]:28470701
[Au] Autor:Bisset CN; Dick L; Chin YR; Summers L; Renwick A
[Ad] Endereço:Department of General Surgery, Royal Alexandra Hospital, Paisley, UK.
[Ti] Título:Re: Bacteriological study in perianal abscess is not useful and not cost-effective.
[So] Source:ANZ J Surg;87(5):420-421, 2017 05.
[Is] ISSN:1445-2197
[Cp] País de publicação:Australia
[La] Idioma:eng
[Mh] Termos MeSH primário: Abscesso
Doenças do Ânus
[Mh] Termos MeSH secundário: Análise Custo-Benefício
Seres Humanos
Fístula Retal
[Pt] Tipo de publicação:LETTER; COMMENT
[Em] Mês de entrada:1801
[Cu] Atualização por classe:180131
[Lr] Data última revisão:
180131
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170505
[St] Status:MEDLINE
[do] DOI:10.1111/ans.13878


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[PMID]:29112567
[Au] Autor:Cranston RD; Regueiro M; Hashash J; Baker JR; Richardson-Harman N; Janocko L; McGowan I
[Ad] Endereço:1 Division of Infectious Diseases, Department of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania 2 Division of Gastroenterology, Hepatology, and Nutrition, Department of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania 3 University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania 4 Alpha StatConsult, Damascus, Maryland 5 Magee-Womens Research Institute, University of Pittsburgh, Pittsburgh, Pennsylvania.
[Ti] Título:A Pilot Study of the Prevalence of Anal Human Papillomavirus and Dysplasia in a Cohort of Patients With IBD.
[So] Source:Dis Colon Rectum;60(12):1307-1313, 2017 Dec.
[Is] ISSN:1530-0358
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Defective cell-mediated immunity increases the risk of human papillomavirus-associated anal dysplasia and cancer. There is limited information on anal canal disease in patients with IBD. OBJECTIVE: The purpose of this study was to assess anal/vaginal human papillomavirus and anal dysplasia prevalence in patients with IBD. DESIGN: Patients had an anal examination before routine colonoscopy. SETTINGS: The study was conducted at a tertiary IBD referral center. PATIENTS: We studied a convenience sample of sexually active male and female patients with IBD who were not on biological therapy. INTERVENTION: Anal examination, anal and vaginal human papillomavirus testing, anal cytology, and high-resolution anoscopy/biopsy were carried out. MAIN OUTCOME MEASURES: Anal and vaginal human papillomavirus types, anal cytology, and biopsy grade were measured. RESULTS: Twenty-five male and 21 female evaluable participants, 31 with Crohn's disease, 14 with ulcerative colitis, and 1 with indeterminate colitis, were predominantly white (91.3%), treatment experienced (76.1%), an average age of 38.1 years (range, 22.0-66.0 y), and had an average length of IBD diagnosis of 9.3 years (range, 1.0-33.0 y). Eighteen (39.1%) had an abnormal perianal examination and 3 (6.5%) had an abnormal digital examination. Forty-one (89.1%) had anal human papillomavirus, 16 with a single type and 25 with multiple types (range, 2-5 types). Human papillomavirus type 16 was most common (65.2%), followed by human papillomavirus types 11 and 45 (37.0% each). Nineteen of 21 (90.5%) women had vaginal human papillomavirus. Overall, 21 (45.7%) had abnormal anal cytology. Thirty three (71.7%) had ≥1 anal biopsy (9 had multiple), with dysplasia diagnosed in 28 (60.9%) and high-grade and low-grade squamous intraepithelial lesions diagnosed in 4 (8.7%) and 24 (43.5%). LIMITATIONS: No control group was included, and no detailed sexual history was taken. CONCLUSIONS: A high prevalence of anal and vaginal human papillomavirus and anal dysplasia was demonstrated in the study population outcomes. See Video Abstract at http://links.lww.com/DCR/A379.
[Mh] Termos MeSH primário: Doenças do Ânus/epidemiologia
Doenças do Ânus/virologia
Doenças Inflamatórias Intestinais/complicações
Papillomaviridae/isolamento & purificação
Infecções por Papillomavirus/epidemiologia
Infecções por Papillomavirus/virologia
Lesões Pré-Cancerosas/epidemiologia
Lesões Pré-Cancerosas/virologia
[Mh] Termos MeSH secundário: Adulto
Idoso
Biópsia
Feminino
Seres Humanos
Masculino
Meia-Idade
Projetos Piloto
Reação em Cadeia da Polimerase
Prevalência
Fatores de Risco
Vagina/virologia
[Pt] Tipo de publicação:JOURNAL ARTICLE; VIDEO-AUDIO MEDIA
[Em] Mês de entrada:1711
[Cu] Atualização por classe:171113
[Lr] Data última revisão:
171113
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171108
[St] Status:MEDLINE
[do] DOI:10.1097/DCR.0000000000000878


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[PMID]:28822559
[Au] Autor:Ghahramani L; Minaie MR; Arasteh P; Hosseini SV; Izadpanah A; Bananzadeh AM; Ahmadbeigi M; Hooshanginejad Z
[Ad] Endereço:Department of surgery, Colorectal Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
[Ti] Título:Antibiotic therapy for prevention of fistula in-ano after incision and drainage of simple perianal abscess: A randomized single blind clinical trial.
[So] Source:Surgery;162(5):1017-1025, 2017 Nov.
[Is] ISSN:1532-7361
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Much controversy exists regarding the role of antibiotics in the development of fistula in-ano after incision and drainage. We evaluated the role of postoperative antibiotics in the prevention of fistula in-ano after incision and drainage of perianal abscess. METHODS: In a randomized single blind clinical trial study, 307 patients were randomly selected from those referring for incision and drainage of perianal abscess at Shahid Faghihi Hospital, Shiraz, Iran, during September 2013 to September 2014. Patients were allocated randomly either to receive 7 days of oral metronidazole and ciprofloxacin in addition to their standard care or to only receive standard care without any antibiotics after they were discharged from the hospital. Patients were followed for 3 months and final results were evaluated. The study was registered at the clinical trial registry (www.irct.ir; Irct201311049936n7). RESULTS: Seven patients were lost to follow-up. Those who used prophylactic antibiotics (n = 155) had significantly lower rates of fistula formation compared with those who did not use any medication (n = 144; P < .001). Men had higher rates of fistula formation (P = .002). Patients who used more cigarettes had higher rates of fistula development (P = .001). In the univariate analysis, only postoperative antibiotic use showed a protective role against fistula formation (odds ratio = 0.426; confidence interval, 0.206-0.881). In the regression analysis postoperative antibiotic use remained protective against fistula development (odds ratio = 0.371; confidence interval, 0.196-0.703), furthermore male sex presented as a risk factor for developing fistula in-ano (odds ratio = 3.11; confidence interval, 1.31-7.38). CONCLUSION: Postoperative prophylactic antibiotic therapy including ciprofloxacin and metronidazole play an important role in preventing fistula in-ano formation. Considering the complications of fistula in-ano formation and the minor side effects of antibiotic therapy, based on our results, a 7-10 course of postoperative antibiotics is advised after incision and drainage of perianal abscess.
[Mh] Termos MeSH primário: Abscesso/cirurgia
Antibacterianos/uso terapêutico
Doenças do Ânus/cirurgia
Drenagem/efeitos adversos
Fístula Retal/prevenção & controle
[Mh] Termos MeSH secundário: Antibioticoprofilaxia
Ciprofloxacino/uso terapêutico
Drenagem/métodos
Seres Humanos
Metronidazol/uso terapêutico
Fístula Retal/etiologia
Método Simples-Cego
Ferida Cirúrgica/complicações
[Pt] Tipo de publicação:JOURNAL ARTICLE; RANDOMIZED CONTROLLED TRIAL
[Nm] Nome de substância:
0 (Anti-Bacterial Agents); 140QMO216E (Metronidazole); 5E8K9I0O4U (Ciprofloxacin)
[Em] Mês de entrada:1711
[Cu] Atualização por classe:171109
[Lr] Data última revisão:
171109
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:170821
[St] Status:MEDLINE


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[PMID]:28807115
[Au] Autor:Duvall MJ; Maxon JA; Lehman JS
[Ad] Endereço:Department of Family Medicine, Mayo Clinic, Rochester, Minnesota.
[Ti] Título:Correlation between HPV status via in situ hybridization testing on genital squamous papillomas and risk for cervical dysplasia or other anogenital HPV-related complications: A case-control study.
[So] Source:J Am Acad Dermatol;77(3):579-580, 2017 09.
[Is] ISSN:1097-6787
[Cp] País de publicação:United States
[La] Idioma:eng
[Mh] Termos MeSH primário: Doenças do Ânus/virologia
Neoplasia Intraepitelial Cervical/virologia
Condiloma Acuminado/virologia
Neoplasias dos Genitais Femininos/virologia
Papiloma/virologia
Infecções por Papillomavirus/virologia
[Mh] Termos MeSH secundário: Células Escamosas Atípicas do Colo do Útero/virologia
Estudos de Casos e Controles
Feminino
Neoplasias dos Genitais Femininos/patologia
Seres Humanos
Hibridização In Situ
Meia-Idade
Teste de Papanicolaou
Papiloma/patologia
Infecções por Papillomavirus/genética
Estudos Retrospectivos
Lesões Intraepiteliais Escamosas Cervicais/virologia
Esfregaço Vaginal
[Pt] Tipo de publicação:LETTER
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170918
[Lr] Data última revisão:
170918
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170816
[St] Status:MEDLINE


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[PMID]:28738938
[Au] Autor:Salfity HV; Valsangkar N; Schultz M; Salfity J; Stanton-Maxey KJ; Zarzaur B; Feliciano DV; Laughlin MR
[Ti] Título:Minimally Invasive Incision and Drainage Technique in the Treatment of Simple Subcutaneous Abscess in Adults.
[So] Source:Am Surg;83(7):699-703, 2017 Jul 01.
[Is] ISSN:1555-9823
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:A minimally invasive (MI) approach using small incisions and vessel loops for drainage of simple perianal abscesses has been described in the pediatric population with decreased postoperative pain and comparable results to the traditional incision and drainage (I&D). The hypothesis was MI I&D will yield similar outcomes in adults. Patients who underwent I&D of perianal abscesses at an urban hospital from January 2008 to December 2015 were identified by Current Procedural Terminology code. Patients below 18 years of age, with inflammatory bowel diseases, or fistulae were excluded. Recurrences, readmissions, operative time, length of stay, complications, and costs were compared. There were 47 traditional and 96 MI I&D with no significant differences in demographics, average body mass index, and abscess size. No significant differences were noted in recurrences, readmissions, length of stay, operative time, or costs (P > 0.05). Postoperative complications occurred more frequently in the traditional group (P < 0.01) with a lower rate of follow-up (P < 0.05). MI I&D for simple anal abscesses in adults is associated with better compliance and fewer complications than the traditional approach. Although further studies are needed to determine if MI I&D confers superiority, this approach should be considered as first-line treatment for uncomplicated perirectal abscesses in adults.
[Mh] Termos MeSH primário: Abscesso/cirurgia
Doenças do Ânus/microbiologia
Doenças do Ânus/cirurgia
Drenagem/métodos
[Mh] Termos MeSH secundário: Adulto
Feminino
Seres Humanos
Masculino
Meia-Idade
Procedimentos Cirúrgicos Minimamente Invasivos
Recidiva
Estudos Retrospectivos
Tela Subcutânea
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170907
[Lr] Data última revisão:
170907
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170726
[St] Status:MEDLINE


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[PMID]:28682970
[Au] Autor:Vollebregt PF; Visscher AP; van Bodegraven AA; Felt-Bersma RJF
[Ad] Endereço:1 Department of Gastroenterology and Hepatology, VU University Medical Center, Amsterdam, the Netherlands 2 Department of Gastroenterology, Geriatrics, Internal Medicine and Intensive Care Medicine, Zuyderland Medical Center, Heerlen-Geleen-Sittard, the Netherlands.
[Ti] Título:Validation of Risk Factors for Fecal Incontinence in Patients With Crohn's Disease.
[So] Source:Dis Colon Rectum;60(8):845-851, 2017 Aug.
[Is] ISSN:1530-0358
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Fecal incontinence has a great impact on daily life, and many patients are reluctant to report it. OBJECTIVE: The purpose of this study was to estimate the prevalence of fecal incontinence in patients with Crohn's disease, validate risk factors, and relate outcome with quality of life. DESIGN: The design was cross-sectional. SETTINGS: The study was conducted at an academic tertiary center. PATIENTS: Consecutive patients with Crohn's disease treated between 2003 and 2013 were included in this study. MAIN OUTCOME MEASURES: A questionnaire was sent out in October 2013 to evaluate perianal disease, current symptoms of fecal incontinence, and its impact on quality of life (Fecal Incontinence Quality of Life questionnaire). Risk factors were validated with univariate and multivariate analyses. RESULTS: The questionnaire was responded by 325 (62%) of 528 patients. Median age was 42 years (range, 18-91 y), 215 (66%) were women, and a diagnosis of Crohn's disease was established for a median period of 12 years (interquartile range, 6-21 y). Fecal incontinence was reported by 65 patients (20%). Fecal incontinence was associated with liquid stools (p = 0.0001), previous IBD-related bowel resections (p = 0.001), stricturing behavior of disease (p = 0.02), and perianal disease (p = 0.03). Quality of life (lifestyle, coping, depression, and embarrassment) was poor in patients with fecal incontinence, particularly in patients with more frequent episodes of incontinence. LIMITATIONS: There was no correction for disease activity in the multivariate regression analysis. CONCLUSIONS: The prevalence of fecal incontinence in a tertiary population with Crohn's disease is substantially higher than in the community-dwelling population. Considering the reduced quality of life in incontinent patients, active questioning to identify fecal incontinence is recommended in those with liquid stools, perianal disease, or previous (intestinal or perianal) surgery. See Video Abstract at http://journals.lww.com/dcrjournal/Pages/videogallery.aspx.
[Mh] Termos MeSH primário: Doenças do Ânus/epidemiologia
Doença de Crohn/epidemiologia
Procedimentos Cirúrgicos do Sistema Digestório/estatística & dados numéricos
Incontinência Fecal/epidemiologia
[Mh] Termos MeSH secundário: Centros Médicos Acadêmicos
Adolescente
Adulto
Fatores Etários
Idoso
Idoso de 80 Anos ou mais
Doença de Crohn/cirurgia
Estudos Transversais
Bases de Dados Factuais
Feminino
Seres Humanos
Masculino
Meia-Idade
Análise Multivariada
Prevalência
Qualidade de Vida
Reprodutibilidade dos Testes
Fatores de Risco
Centros de Atenção Terciária
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE; VALIDATION STUDIES; VIDEO-AUDIO MEDIA
[Em] Mês de entrada:1708
[Cu] Atualização por classe:170828
[Lr] Data última revisão:
170828
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170707
[St] Status:MEDLINE
[do] DOI:10.1097/DCR.0000000000000812


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[PMID]:28651824
[Au] Autor:Bertolotti A; Dupin N; Bouscarat F; Milpied B; Derancourt C
[Ad] Endereço:Centre d'Investigation Clinique Antilles-Guyane, Centre Hospitalier Universitaire de Martinique, Fort-de-France, Martinique; Antilles-Guyane University, Fort-de-France, Martinique. Electronic address: antoine_bertolotti@yahoo.fr.
[Ti] Título:Cryotherapy to treat anogenital warts in nonimmunocompromised adults: Systematic review and meta-analysis.
[So] Source:J Am Acad Dermatol;77(3):518-526, 2017 Sep.
[Is] ISSN:1097-6787
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Cryotherapy is one of the most commonly used therapeutic modalities to treat anogenital warts (AGWs), but this treatment was not clearly established in the recent international recommendations. OBJECTIVE: To compare the efficacy and safety of cryotherapy versus other AGW treatments. METHODS: Through a systematic search of 12 electronic databases, we identified 11 randomized controlled trials, screened from database inception through October 2016, that met the inclusion criteria (including immunocompetent adults with AGWs receiving cryotherapy in 1 of the comparison groups). Primary endpoint was complete clearance of AGW. Risk-for-bias assessment was based on Cochrane Handbook recommendations. Meta-analyses used Review Manager v5.3 software. RESULTS: Cryotherapy efficacy did not appear to differ from that of trichloroacetic acid, podophyllin, or imiquimod. Electrosurgery was weakly associated with better AGW clearance than cryotherapy (risk ratio [RR] 0.80, 95% confidence interval [CI] 0.65-0.99). Cryotherapy was associated with more immediate low-level adverse events (erythema, stinging, or irritation; RR 3.02, 95% CI 1.38-6.61) and immediate pain requiring oral analgesics (RR 2.11, 95% CI 1.07-4.17) but fewer erosions (RR 0.57, 95% CI 0.36-0.90). LIMITATIONS: All but 1 randomized-controlled trial had a high risk for bias. CONCLUSION: With low-level quality of the evidence, cryotherapy is an acceptable first-line therapy to treat AGWs.
[Mh] Termos MeSH primário: Doenças do Ânus/terapia
Condiloma Acuminado/terapia
Crioterapia
Doenças dos Genitais Femininos/terapia
Doenças dos Genitais Masculinos/terapia
[Mh] Termos MeSH secundário: Feminino
Seres Humanos
Masculino
Ensaios Clínicos Controlados Aleatórios como Assunto
[Pt] Tipo de publicação:COMPARATIVE STUDY; JOURNAL ARTICLE; META-ANALYSIS; REVIEW
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170907
[Lr] Data última revisão:
170907
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170628
[St] Status:MEDLINE


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[PMID]:28609809
[Au] Autor:Kentley J; Ooi JL; Potter J; Tiberi S; O'Shaughnessy T; Langmead L; Chin Aleong J; Thaha MA; Kunst H
[Ad] Endereço:Department of Respiratory Medicine, Barts Health NHS Trust, London, UK.
[Ti] Título:Intestinal tuberculosis: a diagnostic challenge.
[So] Source:Trop Med Int Health;22(8):994-999, 2017 Aug.
[Is] ISSN:1365-3156
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:OBJECTIVE: To describe characteristics, presentation, time to diagnosis and diagnostic findings of patients with intestinal tuberculosis (ITB) in a low-burden country. METHOD: Retrospective study of 61 consecutive ITB patients diagnosed between 2008 and 2014 at a large East London hospital. RESULTS: Forty of sixty-one patients were male. Mean age was 34.6 years. 93% of patients were born abroad, mostly from TB-endemic areas (Indian subcontinent: 88%, Africa: 9%). 25% had concomitant pulmonary TB. Median time from symptom onset to ITB diagnosis was 13 weeks (IQR 3-26 weeks). Ten patients were initially treated for IBD, although patients had ITB. The main sites of ITB involvement were the ileocaecum (44%) or small bowel (34%). Five patients had isolated perianal disease. Colonoscopy confirmed a diagnosis of ITB in 77% of those performed. 42 of 61 patients had a diagnosis of ITB confirmed on positive histology and/or microbiology. CONCLUSION: Diagnosis of ITB is often delayed, which may result in significant morbidity. ITB should be excluded in patients with abdominal complaints who come from TB-endemic areas to establish prompt diagnosis and treatment. Diagnosis is challenging but aided by axial imaging, colonoscopy and tissue biopsy for TB culture and histology.
[Mh] Termos MeSH primário: Intestinos/patologia
Tuberculose Gastrointestinal/diagnóstico
[Mh] Termos MeSH secundário: Dor Abdominal/diagnóstico
Dor Abdominal/etiologia
Adulto
África/etnologia
Doenças do Ânus/etiologia
Demografia
Diagnóstico Diferencial
Emigrantes e Imigrantes
Feminino
Seres Humanos
Índia/etnologia
Intestinos/microbiologia
Londres/epidemiologia
Masculino
Estudos Retrospectivos
Migrantes
Tuberculose Gastrointestinal/complicações
Tuberculose Gastrointestinal/epidemiologia
Tuberculose Gastrointestinal/microbiologia
Tuberculose Pulmonar/complicações
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1708
[Cu] Atualização por classe:170816
[Lr] Data última revisão:
170816
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170614
[St] Status:MEDLINE
[do] DOI:10.1111/tmi.12908



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