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  1 / 10996 MEDLINE  
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[PMID]:29480864
[Au] Autor:Khan S; Su S; Jiang K; Wang BM
[Ad] Endereço:Department of Gastroenterology and Hepatology, Tianjin Medical University General Hospital, Tianjin, PR China.
[Ti] Título:Retrograde gastroesophageal intussusception after peroral endoscopic myotomy in a patient with achalasia cardia: A case report.
[So] Source:Medicine (Baltimore);97(2):e9609, 2018 Jan.
[Is] ISSN:1536-5964
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:RATIONALE: Retrograde gastroesophageal intussusception (RGEI) is a relatively rare gastrointestinal (GI) disorder in which a portion of the stomach wall invaginates into the esophagus. More recently, peroral endoscopic myotomy (POEM) has emerged as an endoscopic alternative to surgical myotomy for achalasia, and, to the best of our knowledge, our case is the first RGEI after POEM to be reported. PATIENT CONCERNS: A 22-year-old male was presented with a history of vomiting, intractable retching and hematemesis for 3 days. He had a history of achalasia and underwent POEM 3 years ago caused by symptoms of severe dysphagia to solid and liquid. DIAGNOSES: Initially, the patient was diagnosed with a blood-filled esophagus, and the mid esophagus was occluded with a ball-like mass, however, the final diagnosis of RGEI was made by thoracotomy. INTERVENTIONS: A therapeutic strategy of conservative treatment and left transthoracic surgery were applied. OUTCOMES: The surgery and post operative course were uneventful, and he remained asymptomatic 1 year after operation. LESSONS: POEM is a reliable and minimally invasive endoscopic method for esophageal achalasia. Early recognition and severity of RGEI are essential to decrease the unwanted complications. Upper GI series, esophagogastroduodenoscopy and computed tomography scan are helpful for diagnostic purposes of RGEI. Conservative treatment, endoscopic intervention, and surgery are the mainstay of treatments for RGEI.
[Mh] Termos MeSH primário: Endoscopia Gastrointestinal
Acalasia Esofágica/cirurgia
Intussuscepção/etiologia
Miotomia
Complicações Pós-Operatórias
Gastropatias/etiologia
[Mh] Termos MeSH secundário: Tratamento Conservador
Endoscopia Gastrointestinal/métodos
Acalasia Esofágica/diagnóstico por imagem
Acalasia Esofágica/patologia
Junção Esofagogástrica
Seres Humanos
Intussuscepção/diagnóstico por imagem
Intussuscepção/patologia
Intussuscepção/terapia
Masculino
Miotomia/métodos
Complicações Pós-Operatórias/terapia
Gastropatias/diagnóstico por imagem
Gastropatias/patologia
Gastropatias/terapia
Procedimentos Cirúrgicos Torácicos
Adulto Jovem
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Em] Mês de entrada:1803
[Cu] Atualização por classe:180305
[Lr] Data última revisão:
180305
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:180227
[St] Status:MEDLINE
[do] DOI:10.1097/MD.0000000000009609


  2 / 10996 MEDLINE  
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[PMID]:29256427
[Au] Autor:Ten Doeschate MTI; IJsseldijk LL; Hiemstra S; de Jong EA; Strijkstra A; Gröne A; Begeman L
[Ad] Endereço:Faculty of Veterinary Medicine, Department of Pathobiology, Utrecht University, Yalelaan 1, 3584 CL Utrecht, Netherlands.
[Ti] Título:Quantifying parasite presence in relation to biological parameters of harbour porpoises Phocoena phocoena stranded on the Dutch coast.
[So] Source:Dis Aquat Organ;127(1):49-56, 2017 Dec 19.
[Is] ISSN:0177-5103
[Cp] País de publicação:Germany
[La] Idioma:eng
[Ab] Resumo:Harbour porpoises are often found to be infected by endoparasites in several organs including the lungs and stomach as well as the heart, liver and ears. Nevertheless there is still little knowledge about the impact, ecology, transmission, and virulence of these parasitic infections. Here, we profile the presence of parasites in 4 frequently infected organs (lungs, stomach, liver and ears) in relation to biological parameters of harbour porpoises stranded along the Dutch coastline between December 2008 and December 2013. We found that parasites were common, with prevalence of 68% in lungs, 74.4% in ears, 26% in stomach and 23.5% in liver. We used generalised linear models to further quantify parasite presence in relation to biological data gathered during necropsy (sex, body length and nutritive condition). Body length (used as a proxy for age) was significant in explaining parasite presence for all organs with increasing probability of having the parasite with increasing body length. For the parasitic infections in the ears and stomach the nutritive condition was an additional significant factor, with a higher probability of parasite presence in porpoises in a poorer nutritive condition. The results of this study can be used as a baseline for assessing parasite presence in harbour porpoises and are a first step towards linking parasite infections to basic biological data gathered during necropsy.
[Mh] Termos MeSH primário: Doenças Parasitárias em Animais/parasitologia
Phocoena/parasitologia
[Mh] Termos MeSH secundário: Animais
Otopatias/parasitologia
Otopatias/veterinária
Hepatopatias/parasitologia
Hepatopatias/veterinária
Pneumopatias Parasitárias/veterinária
Países Baixos
Doenças Parasitárias em Animais/patologia
Gastropatias/parasitologia
Gastropatias/veterinária
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1803
[Cu] Atualização por classe:180305
[Lr] Data última revisão:
180305
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171220
[St] Status:MEDLINE
[do] DOI:10.3354/dao03182


  3 / 10996 MEDLINE  
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[PMID]:29390322
[Au] Autor:Søreide JA; Al-Saiddi MSS; Karlsen LN
[Ad] Endereço:Department of Gastrointestinal Surgery.
[Ti] Título:Intramural gastric pseudocyst: A case report and a comprehensive literature review.
[So] Source:Medicine (Baltimore);96(50):e9157, 2017 Dec.
[Is] ISSN:1536-5964
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:RATIONALE: Intramural pseudocyst, although first reported several decades ago, is a rare entity. Scientific knowledge regarding its clinical management is sparse. PATIENT CONCERNS: We present three cases to show the diverse clinical patterns of patients diagnosed with an intramural gastric pseudocyst. DIAGNOSIS: A final diagnosis should rest on proper evaluation by cross sectional imaging, including computer tomography and magnetic resonance imaging. Endoscopic ultrasound adds to the work-up. INTERVENTIONS: Previously, identified "lesions of the gastric wall" were not well recognized as an intramural pseudocyst, and treatments including resectional surgery were employed. Contemporary proper diagnostics should provide support to a less aggressive treatment approach. OUTCOMES: While an indolent natural history without any clinical symptoms or discomfort could be expected in most cases, individual clinical evaluation should be applied. LESSONS: A heterogeneous information pattern from the limited number of cases in the literature makes it difficult to draw any firm conclusions. Attention to this rare condition should be increased to help clinicians arrive at a correct diagnosis and possibly prevent some patients from being over treated or from the use of unnecessary surgery.
[Mh] Termos MeSH primário: Pseudocisto Pancreático/diagnóstico
Gastropatias/diagnóstico
[Mh] Termos MeSH secundário: Idoso
Comorbidade
Diagnóstico Diferencial
Diagnóstico por Imagem
Evolução Fatal
Seres Humanos
Masculino
Meia-Idade
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE; REVIEW
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180301
[Lr] Data última revisão:
180301
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:180203
[St] Status:MEDLINE
[do] DOI:10.1097/MD.0000000000009157


  4 / 10996 MEDLINE  
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[PMID]:28455456
[Au] Autor:Inayat F; Ullah W; Hussain Q; Shafique K
[Ad] Endereço:New York-Presbyterian Hospital, Weill Cornell Medical College, New York City, New York, USA.
[Ti] Título:Crohn's disease presenting as gastric outlet obstruction: a therapeutic challenge?
[So] Source:BMJ Case Rep;2017, 2017 Apr 28.
[Is] ISSN:1757-790X
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Isolated gastric Crohn's disease with initial presentation related to gastric outlet obstruction is an unusual clinicopathological entity. We undertake here a literature review of this rare initial presentation of isolated gastric Crohn's disease and discuss the formidable diagnostic and therapeutic challenges encountered in such patients.
[Mh] Termos MeSH primário: Doença de Crohn/complicações
Doença de Crohn/patologia
Obstrução da Saída Gástrica/complicações
Obstrução da Saída Gástrica/patologia
[Mh] Termos MeSH secundário: Adulto
Doença de Crohn/diagnóstico
Endoscopia do Sistema Digestório/métodos
Endoscopia Gastrointestinal/métodos
Feminino
Obstrução da Saída Gástrica/diagnóstico por imagem
Gastrite/diagnóstico
Gastrite/etiologia
Seres Humanos
Estômago/patologia
Gastropatias/patologia
Tomografia Computadorizada por Raios X/métodos
Resultado do Tratamento
Perda de Peso
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180220
[Lr] Data última revisão:
180220
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170430
[St] Status:MEDLINE


  5 / 10996 MEDLINE  
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[PMID]:29426352
[Au] Autor:Heng HG; Lim CK; Steinbach S; Broman MM; Miller MA
[Ad] Endereço:Department of Veterinary Clinical Sciences, College of Veterinary Medicine, Purdue University, West Lafayette, IN, 47907, USA.
[Ti] Título:Clinical and histopathologic findings in dogs with the ultrasonographic appearance of gastric muscularis unorganized hyperechoic striations.
[So] Source:Acta Vet Scand;60(1):11, 2018 Feb 09.
[Is] ISSN:1751-0147
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Ultrasonographic appearance of unorganized hyperechoic striations (UHS) has been observed in the canine gastric muscularis layer. The purpose of the study was to determine the prevalence, sonographic and postmortem histologic features, and to determine the clinical significance of canine gastric muscularis UHS. In the prospective study, 72 dogs were included. The presence of gastric muscularis UHS were reviewed to determine its distribution and location. In the retrospective study, 167 dogs that had both abdominal ultrasonography and necropsy were included. RESULTS: The prevalence of gastric muscularis UHS in dogs was 37.5% in the prospective and 5.4% in the retrospective studies respectively. The higher prevalence in prospective study was due to greater anticipation by the radiologists in search for gastric muscularis UHS. In the ventral gastric wall, the muscularis UHS were better defined when the gastric lumen was empty or non-distended, and were mostly parallel with the serosa when the gastric wall was distended (with gas or fluid). Visualization of the dorsal gastric wall was often obscured by gas shadowing from luminal gas. Histopathology was performed on eight dogs with gastric muscularis UHS, three of which had fibrous tissue observed with Masson's trichrome stain. CONCLUSION: Presence of gastric muscularis UHS in dogs may have been attributable to presence of incomplete interfaces between the inner oblique, middle circular and outer longitudinal layers of the gastric tunica muscularis or due to presence of fibrous tissue within the gastric muscularis layer. The clinical significance of canine gastric muscularis UHS is uncertain.
[Mh] Termos MeSH primário: Mucosa Gástrica/diagnóstico por imagem
Gastropatias/veterinária
Ultrassonografia
[Mh] Termos MeSH secundário: Animais
Doenças do Cão/diagnóstico por imagem
Doenças do Cão/epidemiologia
Doenças do Cão/patologia
Cães
Mucosa Gástrica/patologia
Prevalência
Estudos Retrospectivos
Gastropatias/diagnóstico por imagem
Gastropatias/epidemiologia
Gastropatias/patologia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180216
[Lr] Data última revisão:
180216
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180211
[St] Status:MEDLINE
[do] DOI:10.1186/s13028-018-0365-9


  6 / 10996 MEDLINE  
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[PMID]:29223168
[Au] Autor:Nonaka H; Onishi H; Ozaki M; Kuriyama K; Komiyama T; Saito R
[Ad] Endereço:Department of Radiology, University of Yamanashi, 1110 Shimokato, Chuo City, Yamanashi, 409-3898, Japan. hnonaka@yamanashi.ac.jp.
[Ti] Título:Serious gastric perforation after second stereotactic body radiotherapy for peripheral lung cancer that recurred after initial stereotactic body radiotherapy: a case report.
[So] Source:J Med Case Rep;11(1):343, 2017 Dec 10.
[Is] ISSN:1752-1947
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: In recent reports, re-irradiation with stereotactic body radiotherapy for lung tumors in patients previously treated with thoracic radiation therapy resulted in several serious toxicities. Serious non-lung toxicities were observed mostly in patients with central tumors, but we experienced a case of fatal gastric perforation after a second stereotactic body radiotherapy in a patient with a peripheral lung tumor. CASE PRESENTATION: An 83-year-old Asian man was diagnosed with T2N0M0 lung cancer in the form of squamous cell carcinoma in the lower lobe of his left lung. He was treated with stereotactic body radiotherapy of 40 Gy in 4 fractions and the tumor decreased in size in partial response. The local tumor recurred 8 months after the first stereotactic body radiotherapy, and he was re-irradiated with a second stereotactic body radiotherapy of 50 Gy in 4 fractions. A Sengstaken-Blakemore tube was inserted below his diaphragm by laparoscopic surgery before the second stereotactic body radiotherapy in order to reduce the stomach dose by keeping his stomach apart from the tumor. Two months after the second stereotactic body radiotherapy, he developed fatal gastric perforation and gastropleural fistula penetrating his diaphragm. CONCLUSIONS: To the best of our knowledge, this is the first report about a gastric perforation after stereotactic body radiotherapy for lung tumors and it warns of serious complication of stereotactic body radiotherapy in not only centrally located but also peripherally located tumors like in this case.
[Mh] Termos MeSH primário: Carcinoma de Células Escamosas/radioterapia
Fístula Gástrica/diagnóstico
Neoplasias Pulmonares/radioterapia
Recidiva Local de Neoplasia/radioterapia
Doenças Pleurais/diagnóstico
Lesões por Radiação/diagnóstico
Radiocirurgia/efeitos adversos
Gastropatias/diagnóstico
[Mh] Termos MeSH secundário: Idoso de 80 Anos ou mais
Evolução Fatal
Gastroscopia
Seres Humanos
Masculino
Retratamento
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Em] Mês de entrada:1801
[Cu] Atualização por classe:180130
[Lr] Data última revisão:
180130
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171211
[St] Status:MEDLINE
[do] DOI:10.1186/s13256-017-1504-z


  7 / 10996 MEDLINE  
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[PMID]:28747090
[Au] Autor:Melendez P; Romero C; Pithua P; Marin MP; Pinedo P; Duchens M
[Ad] Endereço:a Department of Veterinary Medicine and Surgery, College of Veterinary Medicine , University of Missouri , Columbia , MO , USA.
[Ti] Título:Retrospective evaluation of milk production and culling risk following either surgical, toggle-pin suture or conservative treatment of left displaced abomasum in Chilean dairy cows.
[So] Source:N Z Vet J;65(6):292-296, 2017 Nov.
[Is] ISSN:1176-0710
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:AIMS To describe milk yield and culling risk in cows diagnosed with left displacement of abomasum (LDA) treated either conservatively, by right flank pyloric omentopexy, or rolling and toggling, compared with normal herdmates from four Chilean dairy herds. METHODS Historical records were obtained from four commercial dairy farms located in Central Chile for cows with a history of LDA between 2010 and 2012, and healthy herdmates. Cows with LDA were categorised into three groups: cows treated with right omentopexy (ST, n=58), cows treated by toggle suturing (TT, n=15) and cows treated conservatively (CT, n=56). Control cows (n=129) were selected from unaffected cows, matched by days in milk (DIM), parity and herd with affected cows. Groups were compared for risk of culling up to 300 DIM and for milk production up to 5 months of lactation using survival and Cox proportional hazard models and mixed models for repeated measures, respectively. RESULTS Compared with cows in the Control group, the risk of being culled up to 300 DIM was 9.1 (SE 0.62) times greater in ST cows, 10.4 (SE 0.68) times greater in TT cows, and 37.3 (SE 0.61) times greater in CT cows (p<0.01). In the first 5 months of lactation, compared with cows in the Control group, mean daily milk production was 23.3 (SE 1.5) kg less in ST cows, 15.3 (SE 1.6) kg less in TT cows, and 30.1 (SE 1.3) kg less in CT cows (p<0.001). CONCLUSIONS AND CLINICAL RELEVANCE Cows in four dairy herds in central Chile diagnosed and treated for LDA produced significantly less milk and had a higher risk of culling than healthy herdmates. Although cows treated surgically or with toggle suture never recovered to the extent of healthy cows, they produced more milk than cows treated conservatively. However, the retrospective nature of the data, the inclusion of only four herds and the non-random allocation to treatments means that these conclusions cannot be extrapolated to the overall dairy cattle population in Chile.
[Mh] Termos MeSH primário: Abomaso/cirurgia
Doenças dos Bovinos/cirurgia
Tratamento Conservador/veterinária
Leite/metabolismo
Gastropatias/veterinária
[Mh] Termos MeSH secundário: Animais
Bovinos/fisiologia
Doenças dos Bovinos/fisiopatologia
Feminino
Lactação/fisiologia
Estudos Retrospectivos
Gastropatias/fisiopatologia
Gastropatias/cirurgia
Suturas/efeitos adversos
Suturas/veterinária
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1711
[Cu] Atualização por classe:171128
[Lr] Data última revisão:
171128
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170728
[St] Status:MEDLINE
[do] DOI:10.1080/00480169.2017.1360162


  8 / 10996 MEDLINE  
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[PMID]:29073245
[Au] Autor:Scott I; Umair S; Savoian MS; Simpson HV
[Ad] Endereço:Institute of Veterinary, Animal and Biomedical Sciences, Massey University, Palmerston North, New Zealand.
[Ti] Título:Abomasal dysfunction and cellular and mucin changes during infection of sheep with larval or adult Teladorsagia circumcincta.
[So] Source:PLoS One;12(10):e0186752, 2017.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:This is the first integrated study of the effects on gastric secretion, inflammation and fundic mucins after infection with L3 T. circumcincta and in the very early period following transplantation of adult worms. At 3 months-of-age, 20 Coopworth lambs were infected intraruminally with 35,000 L3; infected animals were killed on Days 5, 10, 15, 20 and 30 post-infection and 6 controls on either Day 0 or 30 post-infection. Another 15 Romney cross lambs received 10,000 adult worms at 4-5 months-of-age though surgically-implanted abomasal cannulae and were killed after 6, 12, 24 and 72 hours; uninfected controls were also killed at 72 hours. Blood was collected at regular intervals from all animals for measurement of serum gastrin and pepsinogen and abomasal fluid for pH measurement from cannulated sheep. Tissues collected at necropsy were fixed in Bouin's fluid for light microscopy, immunocytochemistry and mucin staining and in Karnovsky's fluid for electron microscopy. Nodules around glands containing developing larvae were seen on Day 5 p.i., but generalised effects on secretion occurred only after parasite emergence and within hours after transplantation of adult worms. After L3 infection, there were maximum worm burdens on Days 10-15 post-infection, together with peak tissue eosinophilia, inhibition of gastric acid secretion, hypergastrinaemia, hyperpepsinogenaemia, loss of parietal cells, enlarged gastric pits containing less mucin and increased numbers of mucous neck cells. After adult transplantation, serum pepsinogen was significantly increased after 9 hours and serum gastrin after 18 hours. Parallel changes in host tissues and the numbers of parasites in the abomasal lumen suggest that luminal parasites, but not those in the tissues, are key drivers of the pathophysiology and inflammatory response in animals exposed to parasites for the first time. These results are consistent with initiation of the host response by parasite chemicals diffusing across the surface epithelium, possibly aided by components of ES products which increased permeability. Parietal cells appear to be a key target, resulting in secondary increases in serum gastrin, pit elongation, loss of surface mucins and inhibition of chief cell maturation. Inflammation occurs in parallel, and could either cause the pathology or exacerbate the direct effects of ES products.
[Mh] Termos MeSH primário: Mucinas Gástricas/secreção
Doenças dos Ovinos
Ovinos
Gastropatias
Estômago de Ruminante
Trichostrongyloidea
Tricostrongiloidíase
[Mh] Termos MeSH secundário: Animais
Gastrinas/sangue
Larva
Pepsinogênio A/sangue
Ovinos/sangue
Ovinos/parasitologia
Doenças dos Ovinos/sangue
Doenças dos Ovinos/parasitologia
Gastropatias/sangue
Gastropatias/parasitologia
Estômago de Ruminante/parasitologia
Estômago de Ruminante/secreção
Tricostrongiloidíase/sangue
Tricostrongiloidíase/parasitologia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Gastric Mucins); 0 (Gastrins); 9001-10-9 (Pepsinogen A)
[Em] Mês de entrada:1711
[Cu] Atualização por classe:171110
[Lr] Data última revisão:
171110
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171027
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0186752


  9 / 10996 MEDLINE  
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[PMID]:28783738
[Au] Autor:Li T; Lu M; Song J; Wu P; Cheng X; Zhang Z
[Ad] Endereço:Department of Ultrasound, Sichuan Cancer Hospital Institute, Sichuan Cancer Center, School of Medicine, University of Electronic Science and Technology of China, Chengdu, China.
[Ti] Título:Improvement to ultrasonographical differential diagnosis of gastric lesions: The value of contrast enhanced sonography with gastric distention.
[So] Source:PLoS One;12(8):e0182332, 2017.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:OBJECTIVE: The purpose of this retrospective study is to evaluate the diagnostic value of contrast enhanced sonography plus gastric distention sonography, the Double Contrast-enhanced Ultrasound (DCUS) in gastric lesions. METHODS: 107 cases with pathology confirmed gastric lesions were retrospectively reviewed, DCUS and oral contrast agent ultrasound (US) were performed in all cases prior to operation. Perfusion parameters including arrival time (AT), peak intensity (PI), time to peak (TTP), and area under the curve (AUC) of the lesion and surrounding normal tissue were analyzed. A reader blinded to pathology results were asked to rate and compare each case with surgical or resection biopsy pathology results. RESULTS: From the 107 gastric lesions, 75 were malignant gastric lesions (33 gastric cancers,42 gastrointestinal stromal tumors (GISTs)) and 32 were benign gastric lesions (11 inflammatory masses and 21 polypoid adenomas). Compared with US, DCUS achieved higher value in sensitivity (90.6% vs. 70.6%), specificity (75% vs. 62.5%), positive predictive value (89.5% vs. 81.5%), negative predictive value (77.4% vs. 47.6%), and overall accuracy (85.9% vs. 68.2%). When US was tested against DCUS, the increase in correct diagnoses value was significant (P = .01). Furthermore, gastric cancer had faster AT, higher PI and AUC than normal tissue (P<0.05); GIST and Inflammatory mass had higher PI than normal tissue (P<0.05); gastric cancer and GIST had faster AT than polypoid adenoma (P<0.05), Inflammatory mass showed higher PI than other 3 lesions and gastric cancer had higher PI than polypoid adenoma and GIST (P<0.05); gastric cancer and inflammatory mass had larger AUC than polypoid adenoma and GIST (P<0.05). Conclusion DCUS improved diagnostic performance compared with US. The combination of different CEUS enhancement characteristics with quantitative perfusion parameters may provide a promising tool to help differentiate gastric cancer and GIST from benign lesions.
[Mh] Termos MeSH primário: Meios de Contraste
Gastropatias/diagnóstico por imagem
Estômago/diagnóstico por imagem
Ultrassonografia/métodos
[Mh] Termos MeSH secundário: Ar
Diagnóstico Diferencial
Feminino
Seres Humanos
Masculino
Meia-Idade
Estudos Retrospectivos
Sensibilidade e Especificidade
Estômago/patologia
Gastropatias/patologia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Contrast Media)
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171006
[Lr] Data última revisão:
171006
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170808
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0182332


  10 / 10996 MEDLINE  
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[PMID]:28737158
[Au] Autor:Hrabar J; Bocina I; Gudan Kurilj A; Duras M; Mladineo I
[Ad] Endereço:Laboratory for Aquaculture, Institute of Oceanography and Fisheries, 21000 Split, Croatia.
[Ti] Título:Gastric lesions in dolphins stranded along the Eastern Adriatic coast.
[So] Source:Dis Aquat Organ;125(2):125-139, 2017 07 24.
[Is] ISSN:0177-5103
[Cp] País de publicação:Germany
[La] Idioma:eng
[Ab] Resumo:Stranded cetaceans are often found with gastric lesions associated with the presence of parasites; most frequently, nematodes of the genus Anisakis and the heterophyd digenean trematode Pholeter gastrophilus. In this study, we present histopathology mainly (but not exclusively) related to these 2 parasite species. Macroscopically, lesions associated with the presence of Anisakis spp. were characterised by the presence of ulcers within the gastric mucosa, while the digenean P. gastrophilus was found within large submucosal fibrotic nodules in the gastric wall. Anisakis-induced alterations included severe ulcerative gastritis with mixed inflammatory infiltrate often associated with colonies of bacteria, and mild to moderate granulomatous gastritis with eosinophilic infiltrate. P. gastrophilus-associated lesions were characterised by fibrogranulomatous gastritis with mixed inflammatory infiltrate. Additionally, immunohistochemical (IHC) analysis of P. gastrophilus lesions was consistent with the histopathologic findings, revealing inflammation-mediated stimulation. IHC-positive localisation of CD3+, iNOS+ and caspase-3+ cells suggests intensive accumulation of cytotoxic T-cells, proinflammatory cytokines and execution-phase of cell apoptosis at the parasitized area. In contrast, mechanical damage, rather than visible inflammatory response could be observed at the site of attachment of Braunina cordiformis recorded in 4 animals. Lesions not associated with the presence of parasites were mostly characterised by focal loss of superficial epithelial cells and accumulation of brown hemosiderin-like pigment or fibrous gastritis with lymphoplasmacytic infiltrate. In light of these results, we argue that observed 'tolerant' host-parasite interactions that led toward gastric lesions do not represent the cause of death and stranding of cetaceans included in this study.
[Mh] Termos MeSH primário: Golfinhos
Gastropatias/veterinária
Infecções por Trematódeos/veterinária
[Mh] Termos MeSH secundário: Animais
Anisaquíase/epidemiologia
Anisaquíase/patologia
Anisaquíase/veterinária
Anisakis
Feminino
Masculino
Mar Mediterrâneo/epidemiologia
Gastropatias/epidemiologia
Gastropatias/parasitologia
Gastropatias/patologia
Trematódeos/classificação
Trematódeos/isolamento & purificação
Infecções por Trematódeos/epidemiologia
Infecções por Trematódeos/parasitologia
Infecções por Trematódeos/patologia
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171013
[Lr] Data última revisão:
171013
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170725
[St] Status:MEDLINE
[do] DOI:10.3354/dao03137



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