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[PMID]:29390314
[Au] Autor:Sagami R; Tsuji H; Nishikiori H; Murakami K
[Ad] Endereço:Department of Gastroenterology, Oita San-ai Medical Center, Oita city.
[Ti] Título:Endoscopic ultrasound-guided transduodenal drainage of idiopathic retroperitoneal abscess in an immunocompromised patient: A case report.
[So] Source:Medicine (Baltimore);96(50):e9132, 2017 Dec.
[Is] ISSN:1536-5964
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:RATIONALE: Idiopathic retroperitoneal abscesses are insidious, occult illnesses with high mortality if inadequately drained. Endoscopic ultrasound-guided drainage is an alternative to percutaneous or surgical drainage, it is not widely performed for retroperitoneal abscesses other than peripancreatic fluid collection. PATIENT CONCERNS: We present a 76-year-old Japanese woman with abdominal pain, high fever, and a history of rheumatism on treatment with immunosuppressants. DIAGNOSES: The patient was diagnosed with idiopathic retroperitoneal abscess based on results obtained from her clinical course and findings on computed tomography. INTERVENTIONS: We performed Endoscopic ultrasound-guided drainage. After we performed needle puncture via the descending portion of the duodenum, the fistula was expanded using a dilator, and a double-pigtail stent and endoscopic nasobiliary drainage tube were inserted. OUTCOMES: The patient was kept nil by mouth, together with intravenous antibiotic therapy, and repeated washing of the abscess cavity with saline was performed. After that, we confirmed disappearance of the cavity, and, after removing the tubes, commenced oral feeding. We were able to avoid surgery in this immunosuppressed patient. LESSONS: Endoscopic ultrasound (EUS)-guided abscess drainage can be overall considered a safe and useful procedure. We also propose the double-stent method, with both internal and external stents, for the treatment of idiopathic retroperitoneal abscesses.
[Mh] Termos MeSH primário: Abscesso Abdominal/diagnóstico por imagem
Abscesso Abdominal/cirurgia
Endossonografia
Hospedeiro Imunocomprometido
Doenças Peritoneais/diagnóstico por imagem
Doenças Peritoneais/cirurgia
[Mh] Termos MeSH secundário: Idoso
Drenagem
Feminino
Seres Humanos
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180301
[Lr] Data última revisão:
180301
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:180203
[St] Status:MEDLINE
[do] DOI:10.1097/MD.0000000000009132


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[PMID]:29390583
[Au] Autor:Wu YH; Liu KT; Wen CK
[Ad] Endereço:Department of Emergency Medicine, Kaohsiung Medical University Hospital.
[Ti] Título:A rare diagnosis of abdominal pain presentation in the emergency department: Idiopathic omental bleeding: A case report.
[So] Source:Medicine (Baltimore);96(51):e9463, 2017 Dec.
[Is] ISSN:1536-5964
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:RATIONALE: Idiopathic omental bleeding is a rare cause of acute abdomen, with only a few reported cases. It usually presents with abdominal pain and may be life-threatening. As it rarely occurs, it may not be considered initially during patient presentation. PATIENT CONCERNS: A 35-year-old male came to our emergency department with abdominal pain present for around 5 to 6 hours. The patient complained of left upper quadrant abdominal pain after eating breakfast. The only associated symptom was 3 episodes of vomiting up food. Physical examination revealed mild left upper quadrant abdominal tenderness without muscle guarding or rebounding pain. Blood examination showed leukocytosis with neutrophil predominance and C reactive protein elevation. The pain was persistent and relief was not obtained by medication. DIAGNOSES: Computed tomography showed a large lobular-contour homogenous slightly hyperdense lesion without enhancement along the greater curvature of the stomach in the lesser sac. A surgeon was consulted and laparotomy was suggested. Hematoma was found at Morrison pouch, subsplenic fossa, and lesser sac under operation. INTERVENTION: Laparotomy and ligation for hemostasis. OUTCOMES: The patient was discharged with stable condition after 7 days of hospitalization. LESSONS: This diagnosis should be considered in patients presenting with epigastric pain and vomiting after eating while in the emergency department because this disease might be life-threatening. This case highlights 2 important learning points. First, idiopathic omental bleeding could occur after eating in patients without underlying disease or trauma history, and this disease should be taken into consideration when acute abdomen occurs. Second, emergent laparotomy is indicated if the cause of acute abdomen is not clear.
[Mh] Termos MeSH primário: Dor Abdominal/etiologia
Hemorragia/diagnóstico
Omento
Doenças Peritoneais/diagnóstico
[Mh] Termos MeSH secundário: Dor Abdominal/diagnóstico por imagem
Adulto
Serviço Hospitalar de Emergência
Hemorragia/complicações
Hemorragia/diagnóstico por imagem
Hemorragia/cirurgia
Seres Humanos
Masculino
Omento/diagnóstico por imagem
Omento/cirurgia
Doenças Peritoneais/complicações
Doenças Peritoneais/cirurgia
Tomografia Computadorizada por Raios X
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180212
[Lr] Data última revisão:
180212
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:180203
[St] Status:MEDLINE
[do] DOI:10.1097/MD.0000000000009463


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[PMID]:29262869
[Au] Autor:Okoshi K; Mizumoto M; Kinoshita K
[Ad] Endereço:Department of Surgery, The Japan Baptist Hospital, 47 Yamanomoto-cho, Kitashirakawa, Sakyo-ku, Kyoto, 606-8273, Japan. kae_md@kuhp.kyoto-u.ac.jp.
[Ti] Título:Endometriosis-associated hydrocele of the canal of Nuck with immunohistochemical confirmation: a case report.
[So] Source:J Med Case Rep;11(1):354, 2017 Dec 21.
[Is] ISSN:1752-1947
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: The canal of Nuck is an embryological vestige of the processus vaginalis, and presents a potential site for endometriosis seeding. Hydroceles in this region are a rare cause of inguinal swelling in females. In addition, endometriosis localized to the canal of Nuck is exceedingly rare. CASE PRESENTATION: A 44-year-old Japanese woman presented with a painful mass overlying her right pubis. She underwent surgery to completely excise the mass. During surgery, division of the external oblique aponeurosis revealed a cyst that occupied the inguinal canal and it adhered to the transverse fascia, inguinal ligament, and pubic bone. The cyst was dissected from the round ligament, and the defect in the internal inguinal ring was repaired and reinforced with mesh. On macroscopic examination, the cyst had a heterogeneous fibrous aspect with dark brown inclusions. Microscopic examination revealed that the cyst was tortuous, lined by mesothelial-like cells, and accompanied by partial subcapsular hemorrhage. Endometrium-like tissue was observed in the cystic wall. Immunohistochemical staining for podoplanin confirmed the mesothelial origin of the cyst-lining cells. The epithelial cells and stromal cells were positive for estrogen receptors. CONCLUSIONS: In this case of an endometriosis-associated hydrocele of the canal of Nuck, the mesothelial origin of the cyst-lining cells and endometriosis were confirmed by positive immunohistochemical staining for podoplanin and estrogen receptors, respectively. We determined that hydrocele resection and reinforcement of the anterior inguinal canal wall (if necessary) are appropriate treatments for this condition.
[Mh] Termos MeSH primário: Cistos/diagnóstico por imagem
Endometriose/diagnóstico por imagem
Doenças Peritoneais/diagnóstico por imagem
[Mh] Termos MeSH secundário: Adulto
Cistos/metabolismo
Cistos/patologia
Cistos/cirurgia
Endometriose/metabolismo
Endometriose/patologia
Endometriose/cirurgia
Feminino
Seres Humanos
Imuno-Histoquímica
Canal Inguinal
Doenças Peritoneais/metabolismo
Doenças Peritoneais/patologia
Doenças Peritoneais/cirurgia
Receptores Estrogênicos/metabolismo
Tomografia Computadorizada por Raios X
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Receptors, Estrogen)
[Em] Mês de entrada:1801
[Cu] Atualização por classe:180130
[Lr] Data última revisão:
180130
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171222
[St] Status:MEDLINE
[do] DOI:10.1186/s13256-017-1522-x


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[PMID]:29176541
[Au] Autor:Junejo S; Ali Y; Singh Lubana S; Tuli SS
[Ad] Endereço:Icahn School of Medicine at Mount Sinai-Queens Hospital Center, Jamaica, NY, USA.
[Ti] Título:Diffuse Peritoneal and Bowel Wall Infiltration by Light Chain-AL Amyloidosis with Omental Calcification Mimicking Abdominal Carcinomatosis - An Elderly Female with Incidental Finding of Light Chain Monoclonal Gammopathy of Undetermined Significance (LC-MGUS).
[So] Source:Am J Case Rep;18:1247-1250, 2017 Nov 25.
[Is] ISSN:1941-5923
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:BACKGROUND Amyloidosis is the extracellular tissue deposition of plasma proteins, which after conformational changes, forms antiparallel beta pleated sheets of fibrils. Amyloid light-chain (AL) is a type of amyloidosis that is due to deposition of proteins derived from immunoglobulin (Ig) light chains. Gastrointestinal tract (GIT) involvement most often found in amyloid A (AA) amyloidosis type. There have been no reports of obstructive GIT AL amyloid patients having monoclonal gammopathy of undetermined significance (MGUS). Our case is the first case to show two coinciding conditions; one is the association of GIT AL amyloidosis with the incidental finding of a rare type of MGUS (LC-MGUS) and the other is the radiologic presentation of GIT amyloidosis with omental calcification mimicking the GIT malignancy. CASE REPORT A 68-year-old female presented with symptoms of partial bowel obstruction, including intermittent diffuse abdominal pain and constipation. After computed tomography (CT) abdomen and pelvis, an exploratory laparotomy was needed because of suspicion of abdominal carcinomatosis due to diffuse omental calcification. The tissue sent for biopsy surprisingly showed AL amyloidosis. The patient did not report any systemic symptoms. Further workup was advised to inquire about the plasma cell dyscrasia which eventually turned into a very rare version of MGUS knows as light chain MGUS (LC-MGUS). Following adequate resection of the involved structures, the patient was then placed on chemotherapy and successfully went into remission. CONCLUSIONS This case report illustrates that in an era of evidence based medicine, it is important to show through case reports the association of GIT AL amyloidosis with LC-MGUS, as the literature on this topic is lacking. It also points to the importance of timely intervention that can greatly enhance, not only the only the chances of remission but also prevention of further complications such as malignant transformation.
[Mh] Termos MeSH primário: Amiloidose/diagnóstico
Calcinose/diagnóstico
Gamopatia Monoclonal de Significância Indeterminada/diagnóstico
Omento/patologia
Doenças Peritoneais/diagnóstico
[Mh] Termos MeSH secundário: Neoplasias Abdominais/diagnóstico
Idoso
Diagnóstico Diferencial
Feminino
Seres Humanos
Achados Incidentais
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Em] Mês de entrada:1801
[Cu] Atualização por classe:180109
[Lr] Data última revisão:
180109
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171128
[St] Status:MEDLINE


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Alberti, Luiz Ronaldo
Texto completo SciELO Brasil
[PMID]:29236795
[Au] Autor:Garcia DPC; Santos C; Nunes CB; Buzelin MA; Petroianu A; Figueiredo LO; Motta ASD; Gaspar CB; Alberti LR
[Ad] Endereço:PhD, Associate Professor, Department of Surgery, Instituto de Ensino e Pesquisa da Santa Casa, Belo Horizonte-MG, Brazil. Intellectual and scientific content of the study, design the protocol, technical procedures, manuscript writing.
[Ti] Título:Comparative study of intraperitoneal adhesions related to light-weight polypropylene mesh and type I polymerized and purified bovine collagen coated light-weight polypropylene mesh in rabbits.
[So] Source:Acta Cir Bras;32(11):903-912, 2017 Nov.
[Is] ISSN:1678-2674
[Cp] País de publicação:Brazil
[La] Idioma:eng
[Ab] Resumo:PURPOSE: To compare the effectiveness of light-weight polypropylene mesh coated with polymerized and purified bovine type I collagen (Surgidry HNB) in the treatment of abdominal wall defect and the degree of adhesion formation. METHODS: Two types of polypropylene mesh were implanted after creation of defect measuring 6.0cm X 5.5cm in the anterior abdominal wall of 32 male New Zealand breed rabbits, divided in two groups (n = 32): (1) light-weigh macroporous polypropylene, (2) type I polymerized and purified bovine collagen coated light-weigh macroporous polypropylene. These animals were further accessed for adhesions, histological evaluation of inflammation and wall's thickness. RESULTS: The percentage of the area adhered in group 1 (62.31 ± 16.6) was higher compared to group 2 (22.19 ± 14.57) (p <0.05). There was an association between the percentage of the covered area by adhesions and the type of adhesion, toughness and the scores obtained by the adhesion score by correlation analysis (p <0.05). There was no difference between the groups in any variables in relation to the degree of inflammation. CONCLUSION: The purified type I bovine collagen coated light-weigh polypropylene mesh showed to be effective in the repair of abdominal wall defects and reducing adhesion formation.
[Mh] Termos MeSH primário: Parede Abdominal/cirurgia
Colágeno Tipo I
Doenças Peritoneais/prevenção & controle
Polipropilenos
Telas Cirúrgicas
[Mh] Termos MeSH secundário: Animais
Bovinos
Distribuição de Qui-Quadrado
Modelos Animais de Doenças
Masculino
Teste de Materiais
Doenças Peritoneais/patologia
Próteses e Implantes
Coelhos
Aderências Teciduais/patologia
Aderências Teciduais/prevenção & controle
[Pt] Tipo de publicação:COMPARATIVE STUDY; JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Collagen Type I); 0 (Polypropylenes)
[Em] Mês de entrada:1712
[Cu] Atualização por classe:171220
[Lr] Data última revisão:
171220
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171214
[St] Status:MEDLINE


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[PMID]:29180196
[Au] Autor:Marshall JK; Tait N; van der Linden J
[Ad] Endereço:Illawarra Health and Medical Institute, University of Wollongong, Wollongong, Australia. Electronic address: jeankmarshall@gmail.com.
[Ti] Título:Laparotomy causes loss of peritoneal mesothelium prevented by humidified CO insufflation in rats.
[So] Source:J Surg Res;220:300-310, 2017 Dec.
[Is] ISSN:1095-8673
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:INTRODUCTION: Avoiding tissue desiccation is a common recommendation to reduce postoperative complications following open abdominal surgery, although difficult to achieve delicately without damaging the peritoneal mesothelium. Insufflation of humidified-warm CO into the abdomen during open abdominal surgery is proposed as an invisible, effortless way to prevent desiccation. We hypothesized that desiccation during open abdominal surgery would cause loss of peritoneal mesothelium that would be prevented by insufflation of humidified-warm CO . METHODS: Nine Wistar rats were assigned to 1 h of anesthesia only, laparotomy only, or laparotomy with insufflation of humidified-warm CO . Twelve hours after treatment, rats were euthanized and tissue samples were excised. Scanning electron microscopy (SEM) and light microscopy (LM) images of visceral and parietal peritoneum were scored by two independent, blinded examiners for loss of mesothelium and other indications of inflammation, including measurement of apoptosis by detection of DNA cleavage. RESULTS: Loss of peritoneal mesothelium was found in peritoneum exposed to laparotomy only (SEM: P = 0.002; LM: P = 0.01), and mesothelial loss was reduced by humidified-warm CO (SEM: P < 0.001; LM P = 0.004). Similarly, DNA cleavage was significantly higher on the peritoneal surface following laparotomy only, compared with anesthesia only (P = 0.0055) and laparotomy with humidified-warm CO insufflation (P = 0.0003). CONCLUSIONS: In a rat model, exposing the peritoneal mesothelial to conditions that replicate minimum recommended air flow within an operating room causes inadvertent loss of mesothelium and signs of inflammation that can be prevented by insufflating humidified-warm CO into the open abdominal cavity.
[Mh] Termos MeSH primário: Dióxido de Carbono/uso terapêutico
Insuflação/métodos
Laparotomia/efeitos adversos
Doenças Peritoneais/prevenção & controle
[Mh] Termos MeSH secundário: Animais
Epitélio/patologia
Feminino
Doenças Peritoneais/etiologia
Doenças Peritoneais/patologia
Ratos Wistar
[Pt] Tipo de publicação:EVALUATION STUDIES; JOURNAL ARTICLE
[Nm] Nome de substância:
142M471B3J (Carbon Dioxide)
[Em] Mês de entrada:1712
[Cu] Atualização por classe:171211
[Lr] Data última revisão:
171211
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171129
[St] Status:MEDLINE


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[PMID]:28930831
[Au] Autor:Xu SY; Sun K; Xie HY; Zhou L; Zheng SS; Wang W
[Ad] Endereço:aDivision of Hepatobiliary and Pancreatic Surgery, Department of Surgery bKey Laboratory of Combined Multi-organ Transplantation, Ministry of Public Health cKey Laboratory of Organ Transplantation, First Affiliated Hospital, School of Medicine, Zhejiang University, Zhejiang Province, Hangzhou, China dCollaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases eKey Laboratory of Precision Diagnosis and Treatment for Hepatobiliary and Pancreatic Tumor of Zhejiang Province fDepartment of Pathology, First Affiliated Hospital, School of Medicine, Zhejiang University, Zhejiang Province, Hangzhou, China.
[Ti] Título:Accessory spleen located in the right parietal peritoneum: The first case report.
[So] Source:Medicine (Baltimore);96(38):e7957, 2017 Sep.
[Is] ISSN:1536-5964
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:RATIONALE: Accessory spleen is a congenital abnormality caused by failure of the splenic anlage to fuse during embryology. The presence of an accessory spleen located in the parietal peritoneum has not been reported so far, and an accessory spleen situated on the right side is extremely rare. In the present study, we describe the first case of an accessory spleen located in the right parietal peritoneum. PATIENTS CONCERNS: A 65-year-old man, presented with pain in his left abdomen for 1 month. DIAGNOSES: With ultrasonography and computed tomography, it was difficult to determine the accurate location and diagnosis, and an abdominal fibroma was preoperatively considered. INTERVENTIONS: By laparotomy, we found a mass connected to the right parietal peritoneum by a vascular pedicle. We resected it completely, and the gross specimen measured 5.0 × 3.0 × 2.5 cm and was a localized tumor with a capsule. OUTCOMES: Microscopically, sinusoids were visible, as well as scattered lymphoid follicles, eosinophils, histiocytes, plasma cells, neutrophils, and red blood cells, indicative of splenic tissue. Finally, the lesion was diagnosed as an accessory spleen located in the right parietal peritoneum. Postoperatively, he recovered well and was followed up for a 31 months, during which he was well with no complication. LESSONS: We present the first accessory spleen located in the right parietal peritoneum. Awareness of the accessory spleen and familiarity with typical imaging findings are necessary for surgeons to make a precise preoperative diagnosis.
[Mh] Termos MeSH primário: Dor Abdominal/etiologia
Coristoma/patologia
Doenças Peritoneais/patologia
Baço
[Mh] Termos MeSH secundário: Idoso
Coristoma/diagnóstico por imagem
Seres Humanos
Masculino
Doenças Peritoneais/diagnóstico por imagem
Ultrassonografia
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Em] Mês de entrada:1709
[Cu] Atualização por classe:171015
[Lr] Data última revisão:
171015
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:170921
[St] Status:MEDLINE
[do] DOI:10.1097/MD.0000000000007957


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[PMID]:28902871
[Au] Autor:Sbracia M; McKinnon B; Scarpellini F; Marconi D; Rossi G; Simmilion C; Mueller MD; Barnea ER; Mueller M
[Ad] Endereço:Hungaria Center for Endocrinology and Reproductive Medicine, Rome, Italy.
[Ti] Título:PreImplantation Factor in endometriosis: A potential role in inducing immune privilege for ectopic endometrium.
[So] Source:PLoS One;12(9):e0184399, 2017.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Endometriosis is a chronic inflammatory condition characterised by the growth of endometrial epithelial and stromal cells outside the uterine cavity. In addition to Sampson's theory of retrograde menstruation, endometriosis pathogenesis is facilitated by a privileged inflammatory microenvironment, with T regulatory FoxP3+ expressing T cells (Tregs) being a significant factor. PreImplantation Factor (PIF) is a peptide essential for pregnancy recognition and development. An immune modulatory function of the synthetic PIF analog (sPIF) has been successfully confirmed in multiple animal models. We report that PIF is expressed in the epithelial ectopic cells in close proximity to FoxP3+ stromal cells. We provide evidence that PIF interacts with FoxP3+ cells and modulates cell viability, dependent on cell source and presence of inflammatory mediators. Our finding represent a novel PIF-based mechanism in endometriosis that has potential for novel therapeutics.
[Mh] Termos MeSH primário: Endometriose/imunologia
Endométrio/imunologia
Endométrio/metabolismo
Imunidade Inata/genética
Proteínas da Gravidez/fisiologia
[Mh] Termos MeSH secundário: Células Cultivadas
Coristoma/genética
Coristoma/metabolismo
Coristoma/patologia
Endometriose/genética
Endometriose/patologia
Endométrio/patologia
Feminino
Perfilação da Expressão Gênica
Seres Humanos
Imunidade Inata/efeitos dos fármacos
Doenças Ovarianas/genética
Doenças Ovarianas/imunologia
Doenças Ovarianas/patologia
Doenças Peritoneais/genética
Doenças Peritoneais/imunologia
Doenças Peritoneais/patologia
Gravidez
Complicações na Gravidez/genética
Complicações na Gravidez/imunologia
Complicações na Gravidez/patologia
Proteínas da Gravidez/genética
Proteínas da Gravidez/metabolismo
Proteínas da Gravidez/farmacologia
Células Estromais/efeitos dos fármacos
Células Estromais/metabolismo
Células Estromais/patologia
Transcriptoma/efeitos dos fármacos
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Pregnancy Proteins); 0 (preimplantation factor, human)
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171031
[Lr] Data última revisão:
171031
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170914
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0184399


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[PMID]:28796739
[Au] Autor:Faucheron JL; Mancini A; Reche F
[Ad] Endereço:1 Colorectal Unit, Department of Surgery, Michallon University Hospital, Grenoble, France 2 University Grenoble Alps, UMR 5525, CNRS, TIMC-IMAG, Grenoble, France 3 Ambulatory Unit, Department of Surgery, Michallon University Hospital, Grenoble, France.
[Ti] Título:Hedrocele Associated With Full-Thickness Rectal Prolapse: A Very Rare Condition Treated by Ambulatory Laparoscopic Anterior Rectopexy.
[So] Source:Dis Colon Rectum;60(9):992-993, 2017 Sep.
[Is] ISSN:1530-0358
[Cp] País de publicação:United States
[La] Idioma:eng
[Mh] Termos MeSH primário: Escavação Retouterina
Doenças Peritoneais/complicações
Radiografia Abdominal/métodos
Prolapso Retal
[Mh] Termos MeSH secundário: Escavação Retouterina/diagnóstico por imagem
Escavação Retouterina/patologia
Feminino
Seres Humanos
Meia-Idade
Planejamento de Assistência ao Paciente
Doenças Peritoneais/diagnóstico
Doenças Peritoneais/fisiopatologia
Prolapso Retal/diagnóstico por imagem
Prolapso Retal/etiologia
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE; VIDEO-AUDIO MEDIA
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170919
[Lr] Data última revisão:
170919
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170811
[St] Status:MEDLINE
[do] DOI:10.1097/DCR.0000000000000882


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[PMID]:28722107
[Au] Autor:Capobianco A; Cottone L; Monno A; Manfredi AA; Rovere-Querini P
[Ad] Endereço:San Raffaele Scientific Institute, Division of Immunology, Transplantation, and Infectious Diseases, Milan, Italy.
[Ti] Título:The peritoneum: healing, immunity, and diseases.
[So] Source:J Pathol;243(2):137-147, 2017 Oct.
[Is] ISSN:1096-9896
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:The peritoneum defines a confined microenvironment, which is stable under normal conditions, but is exposed to the damaging effect of infections, surgical injuries, and other neoplastic and non-neoplastic events. Its response to damage includes the recruitment, proliferation, and activation of a variety of haematopoietic and stromal cells. In physiological conditions, effective responses to injuries are organized; inflammatory triggers are eliminated; inflammation quickly abates; and the normal tissue architecture is restored. However, if inflammatory triggers are not cleared, fibrosis or scarring occurs and impaired tissue function ultimately leads to organ failure. Autoimmune serositis is characterized by the persistence of self-antigens and a relapsing clinical pattern. Peritoneal carcinomatosis and endometriosis are characterized by the persistence of cancer cells or ectopic endometrial cells in the peritoneal cavity. Some of the molecular signals orchestrating the recruitment of inflammatory cells in the peritoneum have been identified in the last few years. Alternative activation of peritoneal macrophages was shown to guide angiogenesis and fibrosis, and could represent a novel target for molecular intervention. This review summarizes current knowledge of the alterations to the immune response in the peritoneal environment, highlighting the ambiguous role played by persistently activated reparative macrophages in the pathogenesis of common human diseases. Copyright © 2017 Pathological Society of Great Britain and Ireland. Published by John Wiley & Sons, Ltd.
[Mh] Termos MeSH primário: Doenças Peritoneais/fisiopatologia
Peritônio/fisiologia
[Mh] Termos MeSH secundário: Doenças Autoimunes/etiologia
Endometriose/etiologia
Endometriose/imunologia
Endometriose/fisiopatologia
Feminino
Seres Humanos
Imunidade Celular/fisiologia
Doenças Peritoneais/etiologia
Doenças Peritoneais/imunologia
Fibrose Peritoneal/etiologia
Fibrose Peritoneal/imunologia
Fibrose Peritoneal/fisiopatologia
Neoplasias Peritoneais/etiologia
Neoplasias Peritoneais/imunologia
Neoplasias Peritoneais/fisiopatologia
Peritônio/anatomia & histologia
Peritônio/imunologia
Peritonite/etiologia
Peritonite/patologia
Peritonite/fisiopatologia
Serosite/etiologia
Cicatrização/fisiologia
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171002
[Lr] Data última revisão:
171002
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170720
[St] Status:MEDLINE
[do] DOI:10.1002/path.4942



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