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[PMID]:29451668
[Au] Autor:Irugu DVK; Singh A; Ch S; Panuganti A; Acharya A; Varma H; Thota R; Falcioni M; Reddy S
[Ad] Endereço:Department of Otorhinolaryngology and Head & Neck Surgery, All India Institute of Medical Sciences, New Delhi, India.
[Ti] Título:Comparison between early and delayed facial nerve decompression in traumatic facial nerve paralysis - A retrospective study.
[So] Source:Codas;30(1):e20170063, 2018.
[Is] ISSN:2317-1782
[Cp] País de publicação:Brazil
[La] Idioma:eng
[Ab] Resumo:Purpose To study the intraoperative findings in case of early and delayed decompression of facial nerve paralysis and compare their results. Methods Retrospective data analysis of 23 cases of longitudinal temporal bone fracture with House-Brackmann grade V and VI facial nerve paralysis. All cases were thoroughly evaluated and underwent facial nerve decompression through the transmastoid approach. All cases were under regular follow-up till the date of manuscript submission. Results Clinical improvement of the facial nerve function was observed for early vs. delayed facial nerve decompression. In the early decompression group, facial nerve function improved to grade II in eight cases (80%) and grade III in two cases (20%), whereas in the delayed decompression group it improved to grade II in one case (7.70%), grade III in four cases (30.76%), grade IV in seven cases (53.84%), and grade V in one case (7.70%). Conclusions Early decompression of facial nerve provides better results than delayed decompression because it enables early expansion of the nerve.
[Mh] Termos MeSH primário: Traumatismos do Nervo Facial/cirurgia
Paralisia Facial/cirurgia
[Mh] Termos MeSH secundário: Adulto
Descompressão Cirúrgica/métodos
Traumatismos do Nervo Facial/diagnóstico por imagem
Paralisia Facial/diagnóstico por imagem
Feminino
Seres Humanos
Masculino
Meia-Idade
Estudos Retrospectivos
Fraturas Cranianas/fisiopatologia
Fraturas Cranianas/cirurgia
Osso Temporal/lesões
Osso Temporal/cirurgia
Tempo para o Tratamento
Adulto Jovem
[Pt] Tipo de publicação:COMPARATIVE STUDY; JOURNAL ARTICLE
[Em] Mês de entrada:1803
[Cu] Atualização por classe:180306
[Lr] Data última revisão:
180306
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180217
[St] Status:MEDLINE


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[PMID]:28498208
[Au] Autor:Marr K; Carruthers JDA; Humphrey S
[Ad] Endereço:Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada Department of Ophthalmology and Visual Sciences, University of British Columbia, Vancouver, British Columbia, Canada Department of Dermatology and Skin Science, University of British Columbia, Vancouver, British Columbia, Canada.
[Ti] Título:Transient Nerve Damage After Microfocused Ultrasound With Visualization.
[So] Source:Dermatol Surg;43(6):894-896, 2017 06.
[Is] ISSN:1524-4725
[Cp] País de publicação:United States
[La] Idioma:eng
[Mh] Termos MeSH primário: Sobrancelhas
Traumatismos do Nervo Facial/etiologia
Terapia por Ultrassom/efeitos adversos
[Mh] Termos MeSH secundário: Técnicas Cosméticas
Feminino
Seres Humanos
Meia-Idade
Envelhecimento da Pele
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171019
[Lr] Data última revisão:
171019
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170513
[St] Status:MEDLINE
[do] DOI:10.1097/DSS.0000000000001032


  3 / 1779 MEDLINE  
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[PMID]:28438598
[Au] Autor:de Lima VN; Lemos CAA; Faverani LP; Santiago Júnior JF; Pellizzer EP
[Ad] Endereço:Student, São Paulo State University, School of Dentistry, Araçatuba, São Paulo, Brazil. Electronic address: valthierre@hotmail.com.
[Ti] Título:Effectiveness of Corticoid Administration in Orthognathic Surgery for Edema and Neurosensorial Disturbance: A Systematic Literature Review.
[So] Source:J Oral Maxillofac Surg;75(7):1528.e1-1528.e8, 2017 Jul.
[Is] ISSN:1531-5053
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:PURPOSE: The aim of this systematic review was to evaluate the effect of corticosteroid (CS) administration on edema and neural regeneration in orthognathic surgery. MATERIALS AND METHODS: A systematic literature search was conducted using the PubMed (Medline), Cochrane Library, and Scopus databases. The PICO approach was used, in which patients with skeletal dentofacial deformity composed the population; uni- or bimaxillary orthognathic surgery composed the intervention; administration versus no administration of CSs composed the comparison; and decrease in postoperative edema and neurosensory disorders composed the outcome. Thirty of 240 articles were selected and evaluated for their titles and abstracts in relation to the inclusion and exclusion criteria. After duplicate references were eliminated, 8 articles remained. RESULTS: Patients who used CSs had lower rates of edema. In fact, after 4 months, there were no remarkable edema rates. These results suggest that neurosensory disorders resolved after 3 months. In addition, in the early and late periods, administration of CSs did not influence the regression of neurosensory disorders. CONCLUSIONS: Administering CSs in orthognathic surgery improved the regression of facial edema independent of the dosage used but did not influence neurosensory disorders.
[Mh] Termos MeSH primário: Edema/prevenção & controle
Traumatismos do Nervo Facial/prevenção & controle
Glucocorticoides/uso terapêutico
Procedimentos Cirúrgicos Ortognáticos
Complicações Pós-Operatórias/prevenção & controle
[Mh] Termos MeSH secundário: Seres Humanos
Resultado do Tratamento
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Nm] Nome de substância:
0 (Glucocorticoids)
[Em] Mês de entrada:1708
[Cu] Atualização por classe:170831
[Lr] Data última revisão:
170831
[Sb] Subgrupo de revista:AIM; D; IM
[Da] Data de entrada para processamento:170426
[St] Status:MEDLINE


  4 / 1779 MEDLINE  
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[PMID]:28337884
[Au] Autor:Martins DO; Santos FM; Britto LR; Lemos JB; Chacur M
[Ad] Endereço:Department of Anatomy, Institute of Biomedical Sciences, University of São Paulo, São Paula, SP, Brazil.
[Ti] Título:Neurochemical effects of photobiostimulation in the trigeminal ganglion after inferior alveolar nerve injury.
[So] Source:J Biol Regul Homeost Agents;31(1):147-152, 2017 Jan-Mar.
[Is] ISSN:0393-974X
[Cp] País de publicação:Italy
[La] Idioma:eng
[Ab] Resumo:Orofacial pain is associated with peripheral and central sensitization of trigeminal nociceptive neurons. Nerve injury results in release of chemical mediators that contribute to persistent pain conditions. The activation of the transient receptor potential vanilloid 1 (TRPV1), promotes release of calcitonin gene-related peptide (CGRP) and substance P (SP) from trigeminal nerve terminals. CGRP and SP contribute to the development of peripheral hyperalgesia. The expression of SP and CGRP by primary afferent neurons is rapidly increased in response to peripheral inflammation. CGRP receptor activation promotes activation of AMPA receptors, leading to increased firing of neurons which is reflected as central sensitization. In this study we investigated whether inferior alveolar nerve (IAN) injury influences AMPA receptors, CGRP, SP and TRPV1 expression in the trigeminal ganglion (TG). The relative expression of the protein of interest from naive rats was compared to those from injured rats and animals that received low level laser therapy (LLLT). IAN-injury did not change expression of GluA1, GluA2 and CGRP, but increased the expression of TRPV1 and SP. LLLT increases GluA1 and GluA2 expression and decreases TVPV1, SP and CGRP. These results, together with previous behavioral data, suggest that IAN-injury induced changes in the proteins analyzed, which could impact on nociceptive threshold. These data may help to understand the molecular mechanisms of pain sensitization in the TG.
[Mh] Termos MeSH primário: Traumatismos do Nervo Facial/radioterapia
Regulação da Expressão Gênica/efeitos da radiação
Terapia com Luz de Baixa Intensidade
Nervo Mandibular/efeitos da radiação
Gânglio Trigeminal/efeitos da radiação
[Mh] Termos MeSH secundário: Animais
Peptídeo Relacionado com Gene de Calcitonina/genética
Peptídeo Relacionado com Gene de Calcitonina/metabolismo
Traumatismos do Nervo Facial/genética
Traumatismos do Nervo Facial/metabolismo
Traumatismos do Nervo Facial/patologia
Masculino
Nervo Mandibular/metabolismo
Nervo Mandibular/patologia
Neurônios Aferentes/metabolismo
Neurônios Aferentes/patologia
Neurônios Aferentes/efeitos da radiação
Estimulação Luminosa/métodos
Ratos
Ratos Sprague-Dawley
Receptores de AMPA/genética
Receptores de AMPA/metabolismo
Transdução de Sinais
Substância P/genética
Substância P/metabolismo
Canais de Cátion TRPV/genética
Canais de Cátion TRPV/metabolismo
Gânglio Trigeminal/lesões
Gânglio Trigeminal/metabolismo
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Receptors, AMPA); 0 (TRPV Cation Channels); 0 (Trpv1 protein, rat); 0 (glutamate receptor ionotropic, AMPA 1); 0 (glutamate receptor ionotropic, AMPA 2); 33507-63-0 (Substance P); 83652-28-2 (Calcitonin Gene-Related Peptide)
[Em] Mês de entrada:1706
[Cu] Atualização por classe:170601
[Lr] Data última revisão:
170601
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170325
[St] Status:MEDLINE


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[PMID]:28224625
[Au] Autor:Chen P; Knox CJ; Yao L; Li C; Hadlock TA
[Ad] Endereço:Department of Otolaryngology, Massachusetts Eye and Ear Infirmary and Harvard Medical School, Boston, Massachusetts, U.S.A.
[Ti] Título:The effects of venous ensheathment on facial nerve repair in the rat.
[So] Source:Laryngoscope;127(7):1558-1564, 2017 Jul.
[Is] ISSN:1531-4995
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:OBJECTIVE: To investigate the protective effect of autologous venous ensheathment on sutured rat facial nerve and to test whether the ensheathment could improve the functional recovery of repaired nerve and accuracy of axonal growth. STUDY DESIGN: In vivo study. METHODS: Forty-six rats were examined, with six rats serving as normal controls and 40 receiving facial nerve transection and suture repair (SR) or transection and suture repair with an additional venous ensheathment (VE). The rats were then subjected to functional testing, histological assessment of nerve specimens, or retrograde tracing, respectively. RESULTS: At the postoperative day (POD) 60, the venous ensheathment showed no adhesion at the surrounding tissues. No significant difference in neuroma formation was found between the two surgical manipulations (SR and VE groups) (P < 0.05). Retrogradely labeled motoneurons in facial nuclei were extremely disorganized after the facial nerve undertook surgical manipulation. In all manipulated groups, double retrogradely labeled neurons, indicative of aberrant axonal branching during regeneration, could be observed after peripheral manipulation across all time points. With the two facial surgical manipulations, the average count of double-labeled neurons at POD 60 was significantly less than at POD 21 (P < 0.05). CONCLUSION: Autologous venous ensheathment could not help with the functional recovery of facial nerve or improve the accuracy of axonal regeneration. Further studies are warranted to elucidate the effects of venous ensheathment in other motor and sensory nerve models. LEVEL OF EVIDENCE: NA. Laryngoscope, 127:1558-1564, 2017.
[Mh] Termos MeSH primário: Anastomose Cirúrgica/métodos
Axônios/fisiologia
Modelos Animais de Doenças
Traumatismos do Nervo Facial/fisiopatologia
Traumatismos do Nervo Facial/cirurgia
Nervo Facial/fisiopatologia
Nervo Facial/cirurgia
Microcirurgia/métodos
Regeneração Nervosa/fisiologia
Veias/transplante
[Mh] Termos MeSH secundário: Animais
Feminino
Neurônios/patologia
Neurônios/fisiologia
Ratos
Ratos Wistar
Técnicas de Sutura
Vibrissas/inervação
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1708
[Cu] Atualização por classe:170822
[Lr] Data última revisão:
170822
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170223
[St] Status:MEDLINE
[do] DOI:10.1002/lary.26501


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[PMID]:28223251
[Au] Autor:Boublata L; Belahreche M; Ouchtati R; Shabhay Z; Boutiah L; Kabache M; Nadji M; Djenna Z; Bounecer H; Ioualalen N
[Ad] Endereço:Neurosurgery Department, Ali Ait Idir Specialized Hospital, Algiers, Algeria. Electronic address: lotfiboublata@gmail.com.
[Ti] Título:Facial Nerve Function and Quality of Resection in Large and Giant Vestibular Schwannomas Surgery Operated By Retrosigmoid Transmeatal Approach in Semi-sitting Position with Intraoperative Facial Nerve Monitoring.
[So] Source:World Neurosurg;103:231-240, 2017 Jul.
[Is] ISSN:1878-8769
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:INTRODUCTION: Large and giant vestibular schwannomas pose a real problem in their management. The preservation of facial nerve function may limit tumor resection despite the use of intraoperative monitoring of the facial nerve. In Algeria, vestibular schwannomas represent 5% of all intracranial tumors operated on, 80.5% of which are large or giant. METHODS: From January 2010 to December 2015, 151 large and giant vestibular schwannomas were operated in our department. Tumor diameter was between 30 and 60 mm. The most common presenting symptom was hearing loss, which was observed in 41.66% of all our patients. All patients were operated in the semi-sitting position with opening of the posterior wall of the internal auditory canal and under continuous intraoperative facial nerve function monitoring. RESULTS: Tumor resection was total in 126 patients. Anatomic preservation of the facial nerve was the reason for nontotal resection in 25 patients. The facial nerve was anatomically preserved in 149 patients. Two years after surgery, the facial nerve function was grade I-II House-Brackmann (H-B) score in 124 cases (82%), grade III-IV H-B score in 21 cases (14%), and grade V-VI H-B score in 06 cases (04%). The status and the improvement of postoperative facial nerve function depend on 4 factors: anatomic preservation of nerve, stimulation threshold, cystic form, and the presence of train activity. CONCLUSIONS: The development of anesthesia techniques and microsurgery and the systematic use of intraoperative monitoring of the facial nerve have allowed us to move from a life preservation era to another era of preservation of function.
[Mh] Termos MeSH primário: Traumatismos do Nervo Facial/fisiopatologia
Nervo Facial
Monitorização Neurofisiológica Intraoperatória/métodos
Microcirurgia/métodos
Neuroma Acústico/cirurgia
Procedimentos Neurocirúrgicos/métodos
Complicações Pós-Operatórias/fisiopatologia
[Mh] Termos MeSH secundário: Adolescente
Adulto
Idoso
Argélia
Traumatismos do Nervo Facial/etiologia
Traumatismos do Nervo Facial/prevenção & controle
Feminino
Transtornos Neurológicos da Marcha/etiologia
Perda Auditiva/etiologia
Seres Humanos
Masculino
Meia-Idade
Neoplasia Residual
Neuroma Acústico/complicações
Neuroma Acústico/diagnóstico por imagem
Neuroma Acústico/patologia
Procedimentos Neurocirúrgicos/efeitos adversos
Posicionamento do Paciente
Complicações Pós-Operatórias/etiologia
Complicações Pós-Operatórias/prevenção & controle
Estudos Retrospectivos
Zumbido/etiologia
Tomografia Computadorizada por Raios X
Carga Tumoral
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170925
[Lr] Data última revisão:
170925
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170223
[St] Status:MEDLINE


  7 / 1779 MEDLINE  
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[PMID]:28199538
[Au] Autor:Kandinov A; Mutchnick S; Nangia V; Svider PF; Zuliani GF; Shkoukani MA; Carron MA
[Ad] Endereço:Department of Otolaryngology-Head and Neck Surgery, Wayne State University School of Medicine, Detroit, Michigan.
[Ti] Título:Analysis of Factors Associated With Rhytidectomy Malpractice Litigation Cases.
[So] Source:JAMA Facial Plast Surg;19(4):255-259, 2017 Jul 01.
[Is] ISSN:2168-6092
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Importance: This study investigates the financial burden of medical malpractice litigation associated with rhytidectomies, as well as factors that contribute to litigation and poor defendant outcomes, which can help guide physician practices. Objective: To comprehensively evaluate rhytidectomy malpractice litigation. Data Sources and Study Selection: Jury verdict and settlement reports related to rhytidectomy malpractice litigations were obtained using the Westlaw Next database. Use of medical malpractice in conjunction with several terms for rhytidectomy, to account for the various procedure names associated with the procedure, yielded 155 court cases. Duplicate and nonrelevant cases were removed, and 89 cases were included in the analysis and reviewed for outcomes, defendant specialty, payments, and other allegations raised in proceedings. Data were collected from November 21, 2015, to December 25, 2015. Data analysis took place from December 25, 2015, to January 20, 2016. Results: A total of 89 cases met our inclusion criteria. Most plaintiffs were female (81 of 88 with known sex [92%]), and patient age ranged from 40 to 76 years (median age, 56 years). Fifty-three (60%) were resolved in the defendant's favor, while the remaining 36 cases (40%) were resolved with either a settlement or a plaintiff verdict payment. The mean payment was $1.4 million. A greater proportion of cases involving plastic surgeon defendants were resolved with payment compared with cases involving defendants with ear, nose, and throat specialty (15 [36%] vs 4 [24%]). The most common allegations raised in litigation were intraoperative negligence (61 [69%]), poor cosmesis or disfigurement (57 [64%]), inadequate informed consent (30 [34%]), additional procedures required (14 [16%]), postoperative negligence (12 [14%]), and facial nerve injury (10 [11%]). Six cases (7%) involved alleged negligence surrounding a "lifestyle-lift" procedure, which tightens or oversews the superficial muscular aponeurosis system layer. Conclusions and Relevance: In this study, although most cases of rhytidectomy malpractice litigation were resolved in the defendant's favor, cases resulting in payments created substantial financial burden for the defendants. Common factors cited by plaintiffs for pursuing litigation included dissatisfaction with cosmetic outcomes and perceived deficits in informed consent. These factors reinforce the importance of a comprehensive, preoperative informed consent process in which the specific potential risks and outcomes are presented by the surgeon to the patient to limit or avoid postsurgical allegations. Intraoperative negligence and facial nerve injury were significantly more likely to result in poor defendant outcomes. Level of Evidence: NA.
[Mh] Termos MeSH primário: Prova Pericial/legislação & jurisprudência
Traumatismos do Nervo Facial/diagnóstico
Traumatismos do Nervo Facial/etiologia
Consentimento Livre e Esclarecido/legislação & jurisprudência
Imperícia/legislação & jurisprudência
Satisfação do Paciente/legislação & jurisprudência
Complicações Pós-Operatórias/diagnóstico
Complicações Pós-Operatórias/etiologia
Ritidoplastia/legislação & jurisprudência
[Mh] Termos MeSH secundário: Adulto
Idoso
Comunicação
Compensação e Reparação/legislação & jurisprudência
Bases de Dados Factuais
Feminino
Seres Humanos
Masculino
Meia-Idade
Fatores de Risco
Resultado do Tratamento
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170901
[Lr] Data última revisão:
170901
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170216
[St] Status:MEDLINE
[do] DOI:10.1001/jamafacial.2016.1782


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[PMID]:28167016
[Au] Autor:Grinblat G; Prasad SC; Fulcheri A; Laus M; Russo A; Sanna M
[Ad] Endereço:Department of Otology & Skull Base Surgery, Gruppo Otologico, Piacenza, Rome, Italy. Electronic address: golda87@hotmail.com.
[Ti] Título:Lateral skull base surgery in a pediatric population: A 25-year experience in a referral skull base center.
[So] Source:Int J Pediatr Otorhinolaryngol;94:70-75, 2017 Mar.
[Is] ISSN:1872-8464
[Cp] País de publicação:Ireland
[La] Idioma:eng
[Ab] Resumo:OBJECTIVE: To analyze the pathology and surgical outcomes of lateral skull base (LSB) procedures in a pediatric population. STUDY DESIGN: Retrospective case review in a referral skull base center. METHODS: Charts of pediatric patients who underwent defined LSB procedures from 1983 to 2015 for various pathologies were evaluated at our center. A systematic review of literature was performed and our results were compared with the literature. RESULTS: 63 patients presented with 65 diseased ears. The mean age was 13 years. 29 (44.6%) presented with hearing loss and 28 (44.4%) and chronic otorrhea. The most common pathology was petrous bone cholesteatoma (27, 42.5%) followed by vestibular schwannoma (10, 15.8%). Subtotal petrosectomy (24, 35.8%) was the most common surgical procedure followed by, transotic (18, 26.8%). The facial nerve function was preserved in 45 (67.1%) and the hearing in 28 (41.7%) cases respectively. No major complications, including mortality was encountered in our series. CONCLUSION: In rare and extensive pathologies involving the skull base in a pediatric population, the surgeon is posed with the dilemma of trying to achieve facial and hearing preservation while dealing with total tumor clearance. Mastery over LSB procedures can ensure complete disease clearance with optimal functional outcomes. LEVEL OF EVIDENCE: 2b.
[Mh] Termos MeSH primário: Doenças Ósseas/cirurgia
Colesteatoma/cirurgia
Neuroma Acústico/cirurgia
Osso Petroso/cirurgia
Base do Crânio/cirurgia
[Mh] Termos MeSH secundário: Adolescente
Doenças Ósseas/complicações
Criança
Pré-Escolar
Colesteatoma/complicações
Traumatismos do Nervo Facial/epidemiologia
Feminino
Audição
Perda Auditiva/etiologia
Seres Humanos
Lactente
Masculino
Neuroma Acústico/complicações
Procedimentos Neurocirúrgicos
Complicações Pós-Operatórias/epidemiologia
Encaminhamento e Consulta
Estudos Retrospectivos
Vertigem/etiologia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1703
[Cu] Atualização por classe:170817
[Lr] Data última revisão:
170817
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170208
[St] Status:MEDLINE


  9 / 1779 MEDLINE  
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[PMID]:28122652
[Au] Autor:Surmelioglu O; Sencar L; Ozdemir S; Tarkan O; Dagkiran M; Surmelioglu N; Tuncer U; Polat S
[Ad] Endereço:Department of Otorhinolaryngology,Cukurova University,Adana,Turkey.
[Ti] Título:Effects of agmatine sulphate on facial nerve injuries.
[So] Source:J Laryngol Otol;131(3):221-226, 2017 Mar.
[Is] ISSN:1748-5460
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:OBJECTIVE: To evaluate the effect of agmatine sulphate on facial nerve regeneration after facial nerve injury using electron and light microscopy. METHODS: The study was performed on 30 male Wistar albino rats split into: a control group, a sham-treated group, a study control group, an anastomosis group, and an anastomosis plus agmatine sulphate treatment group. The mandibular branch of the facial nerve was dissected, and a piece was removed for histological and electron microscopic examination. RESULTS: Regeneration was better in the anastomosis group than in the study control group. However, the best regeneration findings were seen in the agmatine sulphate treatment group. There was a significant difference between the agmatine group and the others in terms of median axon numbers (p < 0.004) and diameters (p < 0.004). CONCLUSION: Agmatine sulphate treatment with anastomosis in traumatic facial paralysis may enhance nerve regeneration.
[Mh] Termos MeSH primário: Agmatina/farmacologia
Traumatismos do Nervo Facial/tratamento farmacológico
Regeneração Nervosa/efeitos dos fármacos
[Mh] Termos MeSH secundário: Anastomose Cirúrgica
Animais
Nervo Facial/efeitos dos fármacos
Nervo Facial/fisiopatologia
Nervo Facial/cirurgia
Traumatismos do Nervo Facial/fisiopatologia
Traumatismos do Nervo Facial/cirurgia
Masculino
Projetos Piloto
Ratos
Ratos Wistar
Sulfatos/farmacologia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Sulfates); 70J407ZL5Q (Agmatine)
[Em] Mês de entrada:1704
[Cu] Atualização por classe:170407
[Lr] Data última revisão:
170407
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:170127
[St] Status:MEDLINE
[do] DOI:10.1017/S0022215117000147


  10 / 1779 MEDLINE  
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[PMID]:28120059
[Au] Autor:Sturiale CL; La Rocca G; Puca A; Fernandez E; Visocchi M; Marchese E; Sabatino G; Albanese A
[Ad] Endereço:Institute of Neurosurgery, Medical School, Catholic University of Rome, Rome, Italy.
[Ti] Título:Minipterional Craniotomy for Treatment of Unruptured Middle Cerebral Artery Aneurysms. A Single-Center Comparative Analysis with Standard Pterional Approach as Regard to Safety and Efficacy of Aneurysm Clipping and the Advantages of Reconstruction.
[So] Source:Acta Neurochir Suppl;124:93-100, 2017.
[Is] ISSN:0065-1419
[Cp] País de publicação:Austria
[La] Idioma:eng
[Ab] Resumo:Pterional craniotomy (PT) has long been the standard approach for the treatment of middle cerebral artery (MCA) aneurysms, even though it may cause temporalis muscle atrophy, facial nerve injury, and masticatory difficulties. Minipterional craniotomy (MPT) is an alternative approach that may provide the same surgical corridor, limiting the risk of postoperative esthetic and functional complications. From January 2011 to December 2014 we consecutively performed 68 craniotomies for surgical treatment of unruptured MCA aneuryms: 37 were standard PT and 31 were MPT. There were no significant differences in mean age, sex, and aneurysm topography between the two groups. The mean skin incision length was 14 cm in the PT group and 6 cm in the MPT group. According to the Glasgow Outcome Scale (GOS) and modified Rankin Scale (mRS), there were no significant differences in clinical outcome at discharge or follow-up between the two groups. Also, the rates of complete aneurysm exclusion were comparable. However, the number of patients complaining of masticatory disorders was higher among those treated with PT. Finally, the number of complications observed in the PT group was higher than that in the MPT group, but only the differences in mean hospitalization length and necessity for a dural patch for reconstruction were statistically significant. In conclusion, the MPT approach is a safe and effective alternative to the standard PT for the treatment of unruptured MCA aneurysms.
[Mh] Termos MeSH primário: Craniotomia/métodos
Traumatismos do Nervo Facial/epidemiologia
Aneurisma Intracraniano/cirurgia
Artéria Cerebral Média/cirurgia
Atrofia Muscular/epidemiologia
Procedimentos Neurocirúrgicos/métodos
Complicações Pós-Operatórias/epidemiologia
[Mh] Termos MeSH secundário: Idoso
Angiografia Digital
Angiografia Cerebral
Angiografia por Tomografia Computadorizada
Traumatismos do Nervo Facial/etiologia
Feminino
Escala de Resultado de Glasgow
Seres Humanos
Aneurisma Intracraniano/diagnóstico por imagem
Masculino
Meia-Idade
Artéria Cerebral Média/diagnóstico por imagem
Procedimentos Neurocirúrgicos/efeitos adversos
Satisfação do Paciente
Complicações Pós-Operatórias/etiologia
Procedimentos Cirúrgicos Reconstrutivos
Músculo Temporal/patologia
[Pt] Tipo de publicação:COMPARATIVE STUDY; JOURNAL ARTICLE
[Em] Mês de entrada:1711
[Cu] Atualização por classe:171102
[Lr] Data última revisão:
171102
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170126
[St] Status:MEDLINE
[do] DOI:10.1007/978-3-319-39546-3_15



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