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[PMID]:29384969
[Au] Autor:Yang S; Zhang B; Shi Q; Liu J; Xu J; Huo N
[Ad] Endereço:Institute of Stomatology, Chinese PLA General Hospital, Beijing, China.
[Ti] Título:Association of IL-6-174 G/C and IL10-1082 G/A polymorphisms with recurrent aphthous stomatitis risk: A meta-analysis.
[So] Source:Medicine (Baltimore);96(52):e9533, 2017 Dec.
[Is] ISSN:1536-5964
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Recurrent aphthous stomatitis (RAS) is a common oral disease with unknown etiology. The association between IL-6-174 G/C and IL10-1082 G/A polymorphisms and the risk of RAS remains controversial. Therefore, we conducted this meta-analysis to gain more evidence-based information. METHODS: Four online databases, PubMed, Embase, Web of Science, and Cochrane Library, were searched, and the relevant publications were collected. An odds ratio (OR) with a 95% confidence interval (CI) was applied to assess the association of the IL-6-174 G/C and IL10-1082 G/A polymorphisms with RAS susceptibility. RESULTS: Nine published case-control studies with 779 patients and 1016 controls were collected. The overall analysis proved that the IL10-1082 G/A polymorphism was significantly associated with the risk of RAS in a dominant model (GG + AG vs AA: OR = 1.49, 95% CI = 1.10-2.01, P = .01). A subgroup analysis based on ethnicity revealed significant associations in Asian populations in allelic, heterozygote, and dominant models (G vs A: OR = 1.55, 95% CI = 1.04-2.31, P = .03; AG vs AA: OR = 1.76, 95% CI = 1.16-2.67, P = .01; GG + AG vs AA: OR = 2.04, 95% CI = 1.37-3.03, P = .00). The association in Caucasians and people of mixed ethnicity requires further study. No significant association was detected between the IL-6-174 G/C polymorphism and RAS in any of the genetic models. However, subgroup analysis by ethnicity revealed that the Caucasians were more likely to develop RAS in 4 genetic models (G vs C: OR = 2.36, 95% CI = 1.26-4.41, P = .01; GG vs CC: OR = 7.05, 95% CI = 3.50-14.18, P = .00; GG + CG vs CC: OR = 4.28, 95% CI = 2.17-8.45, P = .00; GG vs CG + CC: OR = 2.59, 95% CI = 1.05-6.41, P = .04). In addition, a significantly decreased risk of RAS susceptibility was found in Asians (CG vs CC: OR = 0.27, 95% CI = 0.07-0.99, P = .049; GG + CG vs CC: OR = 0.27, 95% CI = 0.07-0.98, P = .047). CONCLUSION: Our meta-analysis indicated that the IL10-1082 G/A polymorphism is associated with RAS susceptibility, especially in Asians. In contrast, the IL-6-174 G/C polymorphism does not have a statistically significant association with RAS susceptibility. However, it may play a different role during the development of RAS in different ethnicities.
[Mh] Termos MeSH primário: Interleucina-10/genética
Interleucina-6/genética
Estomatite Aftosa/genética
[Mh] Termos MeSH secundário: Alelos
Grupo com Ancestrais do Continente Asiático
Grupo com Ancestrais do Continente Europeu
Seres Humanos
Polimorfismo de Nucleotídeo Único
Fatores de Risco
Estomatite Aftosa/etnologia
[Pt] Tipo de publicação:JOURNAL ARTICLE; META-ANALYSIS
[Nm] Nome de substância:
0 (IL10 protein, human); 0 (IL6 protein, human); 0 (Interleukin-6); 130068-27-8 (Interleukin-10)
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180220
[Lr] Data última revisão:
180220
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:180201
[St] Status:MEDLINE
[do] DOI:10.1097/MD.0000000000009533


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[PMID]:28675014
[Au] Autor:Nan J; Liang L; Li L; Xiaoqin S; Xing J; Yang C
[Ad] Endereço:Dept. of Periodontal and Oral Mucosal Diseases, The Affiliated Stomatological Hospital of Guizhou Medical University, Guiyang 550004, China.
[Ti] Título:[Soluble programmed death-1 and soluble programmed death ligand 1 protein expression and immune status in patients with recurrent aphthous ulcer].
[So] Source:Hua Xi Kou Qiang Yi Xue Za Zhi;35(3):286-290, 2017 Jun 01.
[Is] ISSN:1000-1182
[Cp] País de publicação:China
[La] Idioma:chi
[Ab] Resumo:OBJECTIVE: This study aims to investigate the possible role and significance of soluble programmed death-1 (sPD-1)  /soluble programmed death ligand 1 (sPD-L1) in the immune pathogeneses of recurrent aphthous ulcer (RAU). METHODS: A total of 30 RAU cases (18 cases of minor RAU, 5 cases of major RAU, and 7 cases of herpetiform ulcers) were enrolled in this study. A total of 18 healthy people served as controls. Lymphocyte subsets (CD3⁺, CD4⁺, CD8⁺, CD19⁺, and CD16⁺+56⁺) were investigated by flow cytometric analysis. Humoral immunity (IgG, IgA, IgM, C3, and C4) was explored by nephelometry immunoassay. The sPD-1 and sPD-L1 protein levels in the sera of RAU patients were investigated by enzyme-linked immunosorbent assay. The correlations of the sPD-1 and sPD-L1 protein levels with the immune status and clinical characteristics of the RAU patients were analyzed by SPSS 19.0. RESULTS: The number of CD4+ T cells decreased and the levels of IgM antibodies increased in the RAU patients relative to those in the normal controls (P<0.05). The sPD-1 and sPD-L1 protein levels in the RAU patients were significantly higher than those in the control group (P<0.05). Meanwhile, the sPD-1 and sPD-L1 protein levels in the patients with minor and major RAU were significantly higher than those in the control group (P<0.05). By contrast, no significant difference was found in the patients with herpetiform RAU (P>0.05). Positive correlations were noted between the sPD-1 protein level and the CD19+ cell frequency or C4 level (r1=0.389, P1=0.034; r2=0.382, P2=0.037). CONCLUSIONS: Cellular immune hypofunction and humoral immunity disorders were found in the RAU patients. The PD-1/PD-L1 signaling pathway, which might be influenced by the involvement of sPD-1 and sPD-L1 proteins to a certain extent, may play some roles in the immune pathogenesis of RAU.
[Mh] Termos MeSH primário: Antígeno B7-H1
Receptor de Morte Celular Programada 1
Estomatite Aftosa
[Mh] Termos MeSH secundário: Contagem de Células
Ensaio de Imunoadsorção Enzimática
Citometria de Fluxo
Seres Humanos
Transdução de Sinais
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (B7-H1 Antigen); 0 (PDCD1 protein, human); 0 (Programmed Cell Death 1 Receptor)
[Em] Mês de entrada:1708
[Cu] Atualização por classe:171116
[Lr] Data última revisão:
171116
[Sb] Subgrupo de revista:D; IM
[Da] Data de entrada para processamento:170705
[St] Status:MEDLINE
[do] DOI:10.7518/hxkq.2017.03.011


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[PMID]:28573247
[Au] Autor:Shahriari R; Salari S; Shahriari S
[Ad] Endereço:Department of Pathobiology, Faculty of Veterinary Medicine, University of Zabol, P.O. Box 98615-538, Zabol, 9861335856 Iran.
[Ti] Título: STUDY OF CONCENTRATION-EFFECT AND TIME-COURSE PATTERN OF WHITE ALUM ON O157:H7 GROWTH.
[So] Source:Afr J Tradit Complement Altern Med;14(2):311-318, 2017.
[Is] ISSN:2505-0044
[Cp] País de publicação:Nigeria
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Nowadays, the demand for antibacterial fabrics has increased. White alum is used for oral aphthous ulcers treatment in traditional medicine of Sistan city, Sistan and Baluchistan Province, Iran, and also as a flocculent for water purification. This study is aimed to evaluate the effect of concentration and time on antibacterial activity of white alum on O157:H7. MATERIALS AND METHODS: 0.25, 0.5, 1 and 2% concentrations of white alum were added to 10 CFU of O157:H7. Optical Density was recorded for 4 hours. Data obtained were analyzed using Repeated Measure and One-way ANOVA by SPSS. RESULTS: Results revealed the effectiveness of white alum in the growth of the tested bacterium. The white alum was found to be potent against O157:H7 at a concentration above 1% (p<0.05). Also, its effect is dose and time dependent, as well as other disinfectants. CONCLUSION: A wide variety of natural products has been under scrutiny for their clinical potential, both in terms of prevention and treatment. Strong antibacterial activity of white alum compared with control was shown against tested bacterium. In conclusion, white alum can be used as an inhibitor of bacterial growth, especially for O157:H7.
[Mh] Termos MeSH primário: Compostos de Alúmen/farmacologia
Produtos Biológicos/farmacologia
Escherichia coli O157/efeitos dos fármacos
Minerais/farmacologia
[Mh] Termos MeSH secundário: Escherichia coli O157/crescimento & desenvolvimento
Irã (Geográfico)
Estomatite Aftosa/tratamento farmacológico
Purificação da Água
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Alum Compounds); 0 (Biological Products); 0 (Minerals); 34S289N54E (aluminum sulfate)
[Em] Mês de entrada:1708
[Cu] Atualização por classe:170816
[Lr] Data última revisão:
170816
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170603
[St] Status:MEDLINE
[do] DOI:10.21010/ajtcam.v14i2.32


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[PMID]:28480862
[Au] Autor:Kovach I; Kravchenko L; Khotimska Y; Nazaryan R; Gargin V
[Ad] Endereço:State Establishment "Dnipropetrovsk Medical Academy", *Kharkiv National Medical University, Ukraine.
[Ti] Título:INFLUENCE OF OZONE THERAPY ON ORAL TISSUE IN MODELING OF CHRONIC RECURRENT APHTHOUS STOMATITIS.
[So] Source:Georgian Med News;(264):115-119, 2017 Mar.
[Is] ISSN:1512-0112
[Cp] País de publicação:Georgia (Republic)
[La] Idioma:eng
[Ab] Resumo:Chronic recurrent aphthous stomatitis (CRAS) belongs to the group of chronic, inflammatory, ulcerative diseases of the oral mucosa. The aim of this study was to determine the effects of ozone on the morphofunctional peculiarities of the soft tissues in modeling chronic recurrent aphthous stomatitis. We performed experimental investigation for study of the morpho-functional state of tissues of the oral mucosa in CRAS with using of previously proposed and widely used modeling scheme with ovalbumin and aluminum hydroxide. Two groups of animals were formed (Dutch rabbits, males, aging three-month, weighting 2-2.4 kg). Group of 8 animals with obtained mucosal changes was our comparison group. Other group of 8 animals with obtained mucosal changes was treated by ozone therapy. Histological investigation has been performed. Microscopical examination of tissue had shown that ozone therapy reduces inflammation and edema and is useful in wound healing in soft tissue as disappearance of necrobiotic processes, epithelialization of aphthous defect, growth of akantotic bands, pronounced reducing of inflammatory cells and changing of cellular ratio (with of neutrophils part from 38.30±2.46% to 6.34±0.63%, eosinophils from 5.49±0.23% to 2.87±0.05%), restoration of the cellular layers of the epithelium, moderately pronounced sclerosis of the papillary layer of the lamina propria. Described results allow to conclude that correction of tissual changes in chronic recurrent aphthous stomatitis could be obtained with ozone therapy using.
[Mh] Termos MeSH primário: Ozônio/uso terapêutico
Estomatite Aftosa/terapia
[Mh] Termos MeSH secundário: Animais
Doença Crônica
Células Epiteliais/patologia
Masculino
Mucosa Bucal/patologia
Coelhos
Recidiva
Estomatite Aftosa/patologia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
66H7ZZK23N (Ozone)
[Em] Mês de entrada:1708
[Cu] Atualização por classe:170808
[Lr] Data última revisão:
170808
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170509
[St] Status:MEDLINE


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[PMID]:28411006
[Au] Autor:Yarom N; Zelig K; Epstein JB; Gorsky M
[Ad] Endereço:Oral Medicine Unit, The Chaim Sheba Medical Center, Tel Hashomer, Israel; Department of Oral Pathology and Oral Medicine, The Maurice and Gabriela Goldschleger School of Dental Medicine, Tel Aviv University, Tel Aviv, Israel. Electronic address: noam.yarom@sheba.health.gov.il.
[Ti] Título:The efficacy of minocycline mouth rinses on the symptoms associated with recurrent aphthous stomatitis: a randomized, double-blind, crossover study assessing different doses of oral rinse.
[So] Source:Oral Surg Oral Med Oral Pathol Oral Radiol;123(6):675-679, 2017 Jun.
[Is] ISSN:2212-4411
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:OBJECTIVE: The aim of the study was to assess the efficacy of 2 different concentrations of minocycline mouthwashes on the symptoms of recurrent aphthous stomatitis (RAS). STUDY DESIGN: The 2-year study was designed as a randomized, double-blind, crossover study. Healthy patients with frequent RAS episodes received 2 sealed and computer-randomized marked kits containing minocycline mouthwashes (0.2% and 0.5% solution). The patients were asked to use 1 of the kits on the first episode of RAS, starting with the first onset of prodromal symptoms, until the symptoms resolved or up to a maximum of 10 days (whichever came first). The patients were asked to use their second kit during a subsequent episode. RESULTS: A total of 14 patients (8 males, 6 females) completed the 2 arms of the study. The mean intensity of pain was significantly lower when the 0.5% solution was used compared with the 0.2% solution (P = .027). The difference reached the level of statistical significance as soon as the end of the second day of use (P = .032). Only minor and temporary adverse reactions were documented. CONCLUSIONS: We found that 0.5% minocycline mouth rinse was more effective than the 0.2% concentration, which had been suggested by our group in previous studies for the management of RAS.
[Mh] Termos MeSH primário: Antibacterianos/uso terapêutico
Minociclina/uso terapêutico
Antissépticos Bucais/uso terapêutico
Estomatite Aftosa/tratamento farmacológico
[Mh] Termos MeSH secundário: Adulto
Antibacterianos/administração & dosagem
Estudos Cross-Over
Método Duplo-Cego
Feminino
Seres Humanos
Masculino
Meia-Idade
Minociclina/administração & dosagem
Recidiva
Resultado do Tratamento
[Pt] Tipo de publicação:JOURNAL ARTICLE; RANDOMIZED CONTROLLED TRIAL
[Nm] Nome de substância:
0 (Anti-Bacterial Agents); 0 (Mouthwashes); FYY3R43WGO (Minocycline)
[Em] Mês de entrada:1711
[Cu] Atualização por classe:171108
[Lr] Data última revisão:
171108
[Sb] Subgrupo de revista:D; IM
[Da] Data de entrada para processamento:170416
[St] Status:MEDLINE


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[PMID]:28359996
[Au] Autor:Yilmaz HG; Albaba MR; Caygur A; Cengiz E; Boke-Karacaoglu F; Tumer H
[Ad] Endereço:Department of Periodontology, Faculty of Dentistry, Near East University, Mersin, Turkey. Electronic address: guneyyilmaz@hotmail.com.
[Ti] Título:Treatment of recurrent aphthous stomatitis with Er,Cr:YSGG laser irradiation: A randomized controlled split mouth clinical study.
[So] Source:J Photochem Photobiol B;170:1-5, 2017 May.
[Is] ISSN:1873-2682
[Cp] País de publicação:Switzerland
[La] Idioma:eng
[Ab] Resumo:The present randomized controlled split mouth clinical study aimed to investigate the efficacy of Er,Cr:YSGG laser irradiation on pain reduction and healing rate of recurrent aphthous stomatitis. 40 patients with RAS were recruited for this study and RAS ulcerations of each patient were randomly assigned to the control or test group. In the test group, Er,Cr:YSGG laser with non-contact mode was used to irradiate RAS lesions. In the placebo group, RAS lesions were irradiated with the same device without laser emission. Pain was evaluated with visual analog scale (VAS) while a clinician graded healing of RAS (HRAS). In the placebo group at immediate; scores of VAS presented no statistically significance; in the test group, laser application showed significant pain reducing, at 1st day control. In the test group, a significantly healing effect at 1st day control was observed and this effect was maintained throughout the study. In the placebo group, scores of HRAS were statistically significant at controls on 3, 7, 10days. Statistically significant difference between the scores of VAS and HRAS was found for all control days except day 10 according to the intergroup comparisons. Based on these findings, Er,Cr:YSGG laser application at 0.25W without water may be appropriate to reduce pain and also accelerate the healing of RAS.
[Mh] Termos MeSH primário: Lasers de Estado Sólido/uso terapêutico
Estomatite Aftosa/radioterapia
[Mh] Termos MeSH secundário: Adolescente
Adulto
Feminino
Seres Humanos
Terapia com Luz de Baixa Intensidade
Masculino
Meia-Idade
Medição da Dor/efeitos da radiação
Resultado do Tratamento
Cicatrização/efeitos da radiação
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE; RANDOMIZED CONTROLLED TRIAL
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170920
[Lr] Data última revisão:
170920
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170401
[St] Status:MEDLINE


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[PMID]:28345122
[Au] Autor:Suter VGA; Sjölund S; Bornstein MM
[Ad] Endereço:Department of Oral Surgery and Stomatology, School of Dental Medicine, University of Bern, Freiburgstrasse 7, 3010, Bern, Switzerland.
[Ti] Título:Effect of laser on pain relief and wound healing of recurrent aphthous stomatitis: a systematic review.
[So] Source:Lasers Med Sci;32(4):953-963, 2017 May.
[Is] ISSN:1435-604X
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:The aim of this systematic review was to assess a potential benefit of laser use in the treatment of recurrent aphthous stomatitis (RAS). The primary outcome variables were pain relief, duration of wound healing and reduction in episode frequency. A PICO approach was used as a search strategy in Medline, Embase and Cochrane databases. After scanning and excluding titles, abstracts and full texts, 11 studies (ten RCTs and one non-randomised controlled trial) were included. Study selection and data extraction was done by two observers. Study participants varied between 7-90 for the laser and 5-90 for the control groups. Laser treatment included Nd:YAG laser ablation, CO laser applied through a transparent gel (non-ablative) and diode laser in a low-level laser treatment (LLLT) mode. Control groups had placebo, no therapy or topical corticosteroid treatment. Significant pain relief immediately after treatment was found in five out of six studies. Pain relief in the days following treatment was recorded in seven studies. The duration of RAS wound healing was also reduced in five studies. However, criteria of evaluation differed between the studies. The episode frequency was not evaluated as only one study addressed this outcome parameter, but did not discriminate between the study (LLLT) and control (corticosteroid) groups. Jadad scores (ranging from 0 to 5) for quality assessment of the included studies range between 0 and 2 (mean = 1.0) for studies analysing pain relief and between 0 and 3 (mean = 1.1) for studies evaluating wound healing. The use of lasers (CO laser, Nd:YAG laser and diode laser) to relieve symptoms and promote healing of RAS is a therapeutic option. More studies for laser applications are necessary to demonstrate superiority over topical pharmaceutical treatment and to recommend a specific laser type, wavelength, power output and applied energy (ablative versus photobiomodulation).
[Mh] Termos MeSH primário: Terapia a Laser
Dor/radioterapia
Estomatite Aftosa/radioterapia
Cicatrização/efeitos da radiação
[Mh] Termos MeSH secundário: Seres Humanos
Lasers de Gás/uso terapêutico
Lasers Semicondutores/uso terapêutico
Lasers de Estado Sólido/uso terapêutico
Recidiva
[Pt] Tipo de publicação:JOURNAL ARTICLE; META-ANALYSIS; REVIEW
[Em] Mês de entrada:1707
[Cu] Atualização por classe:171013
[Lr] Data última revisão:
171013
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170328
[St] Status:MEDLINE
[do] DOI:10.1007/s10103-017-2184-z


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[PMID]:28343210
[Au] Autor:Semianchuk VB
[Ad] Endereço:State Higher Educational Institution "Ivano-Frankivsk National Medical University", Department Of Children Diseases Of Postgraduate Medical Education Faculty, Ivano-Frankivsk, Ukraine.
[Ti] Título:Periodic fever, aphthous stomatitis, pharyngitis and cervical adenitis (pfapa) syndrome in children.
[So] Source:Wiad Lek;70(1):144-147, 2017.
[Is] ISSN:0043-5147
[Cp] País de publicação:Poland
[La] Idioma:eng
[Ab] Resumo:INTRODUCTION: Periodic fever, aphthous stomatitis, pharyngitis and cervical adenitis (PFAPA) syndrome refers to a group of primary immunodeficiencies, namely autoinflammatory diseases. Most pediatricians and otolaryngologists do not suspect PFAPA syndrome when treating recurrent pharyngitis (according to Ukrainian classification - tonsillitis) and stomatitis. Therefore, patients with a given syndrome receive unnecessary treatment (antibiotic therapy or antiviral drugs) and the diagnosis is made late. The aim of the research was to provide pediatricians, family physicians and otolaryngologists with information on the importance of early diagnosis of PFAPA syndrome. MATERIALS AND METHODS: The analysis of the prevalence and diagnosis of PFAPA syndrome in Ukraine and worldwide has been made as well as a late diagnosis of PFAPA syndrome in a child living in Ivano-Frankivsk, Ukraine has been described (case report). RESULTS: The Сase report 7-year-old boy, who grows and develops normally. The symptoms of pharyngitis including high body temperature (>40 º С), sore throat and white spots on the tonsils appeared for the first time at the age of two years. The boy received antibacterial drugs about 10 times a year. During a four-year period of recurrent episodes of the disease antimicrobial susceptibility testing to determine susceptibility of the oropharyngeal flora to the antibiotics were continuously performed, different blood tests for herpes viruses, Epstein-Barr virus infection and cytomegalovirus in particular were made using the enzyme immunoassay (EIA) and polymerase chain reaction (PCR) in addition to long-term treatment. CONCLUSIONS: An example of late diagnosing PFAPA syndrome (four years after the onset of first symptoms) resulting in regular examinations, medical manoeuvres, outpatient and inpatient treatment, use of antibiotic therapy including intravenous injections on a monthly basis has been studied.
[Mh] Termos MeSH primário: Febre/diagnóstico
Linfadenite/diagnóstico
Faringite/diagnóstico
Estomatite Aftosa/diagnóstico
[Mh] Termos MeSH secundário: Criança
Diagnóstico Tardio
Febre/tratamento farmacológico
Seres Humanos
Linfadenite/tratamento farmacológico
Masculino
Faringite/tratamento farmacológico
Estomatite Aftosa/tratamento farmacológico
Síndrome
Ucrânia
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Em] Mês de entrada:1707
[Cu] Atualização por classe:170713
[Lr] Data última revisão:
170713
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170327
[St] Status:MEDLINE


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[PMID]:28329497
[Au] Autor:Gupta N; Levitt JO
[Ti] Título:Unique clinical presentations of pityriasis rosea: aphthous ulcers, vesicles and inverse distribution of lesions.
[So] Source:Dermatol Online J;23(2), 2017 Feb 15.
[Is] ISSN:1087-2108
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Pityriasis Rosea (PR) is a common skin disorderencountered in daily practice. Although its etiologyhas not been established, there has been widespreadresearch into possibilities. The lack of its characteristicmanifestations, specifically the herald patch andtruncal involvement, can lead to pitfalls in diagnosis.Whereas other conditions in the differential diagnosisshould be considered, PR can at times also manifest inan atypical manner. We wish to illustrate three casesof PR including those that presented with aphthousulcers, vesicles, and an inverse pattern.
[Mh] Termos MeSH primário: Pitiríase Rósea/diagnóstico
Dermatopatias Vesiculobolhosas/diagnóstico
Estomatite Aftosa/diagnóstico
[Mh] Termos MeSH secundário: Administração Cutânea
Administração Oral
Corticosteroides/uso terapêutico
Antivirais/uso terapêutico
Emolientes/uso terapêutico
Antagonistas dos Receptores Histamínicos/uso terapêutico
Seres Humanos
Pitiríase Rósea/complicações
Pitiríase Rósea/terapia
Dermatopatias Vesiculobolhosas/etiologia
Dermatopatias Vesiculobolhosas/terapia
Estomatite Aftosa/etiologia
Estomatite Aftosa/terapia
Terapia Ultravioleta
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Adrenal Cortex Hormones); 0 (Antiviral Agents); 0 (Emollients); 0 (Histamine Antagonists)
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171016
[Lr] Data última revisão:
171016
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170323
[St] Status:MEDLINE


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[PMID]:28299876
[Au] Autor:Yangui I; Zouaoui Boutiti M; Boussaid M; Messaoud C
[Ad] Endereço:Laboratory of Management and Valorization of Forest Resources, National Institute for Research on Rural Engineering, Water and Forestry, BP. N.2, Ariana, 2080, Tunisia.
[Ti] Título:Essential Oils of Myrtaceae Species Growing Wild in Tunisia: Chemical Variability and Antifungal Activity Against Biscogniauxia mediterranea, the Causative Agent of Charcoal Canker.
[So] Source:Chem Biodivers;14(7), 2017 Jul.
[Is] ISSN:1612-1880
[Cp] País de publicação:Switzerland
[La] Idioma:eng
[Ab] Resumo:The chemical composition of five Eucalyptus species and five Myrtus communis L. populations was investigated using GC/MS and GC-FID. For Eucalyptus essential oils, 32 compounds, representing 88.56 - 96.83% of the total oil according to species, were identified. The main compounds were 1,8-cineole, α-pinene, p-cymene, γ-gurjunene, α-aromadendrene, and ß-phellandrene. For Myrtle essential oils, 26 compounds, representing 93.13 - 98.91% of the total oil were identified. α-Pinene, 1,8-cineole, linalool, and myrtenyl acetate were found to be the major compounds. Principal component analysis (PCA) showed chemical differentiation between Eucalyptus species and between Myrtle populations. Biscogniauxia mediterranea, the causative agent of charcoal canker, was identified according to its morphological and molecular characteristics. Essential oils of the investigated Eucalyptus species and Myrtle populations were tested for their antifungal capacity against this fungus. The antifungal activity varied according to the essential oil composition. Biscogniauxia mediterranea exhibited powerful resistance to some essential oils including them of Eucalyptus lehmannii and Eucalyptus sideroxylon but it was very sensitive to Eucalyptus camaldulensis oil (IC  = 3.83 mg/ml) and M. communis oil from Zaghouan (IC  = 1 mg/ml). This sensitivity was found to be correlated to some essential oil compounds such as p-cymene, carvacrol, cuminaldehyde, and linalool.
[Mh] Termos MeSH primário: Antifúngicos/isolamento & purificação
Myrtaceae/química
Óleos Voláteis/química
Estomatite Aftosa/microbiologia
[Mh] Termos MeSH secundário: Antifúngicos/farmacologia
Benzaldeídos
Eucalyptus/química
Monoterpenos
Myrtus/química
Óleos Voláteis/farmacologia
Tunísia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Antifungal Agents); 0 (Benzaldehydes); 0 (Monoterpenes); 0 (Oils, Volatile); 1G1C8T1N7Q (4-cymene); 9B1J4V995Q (carvacrol); D81QY6I88E (linalool); O0893NC35F (cuminaldehyde)
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170922
[Lr] Data última revisão:
170922
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170317
[St] Status:MEDLINE
[do] DOI:10.1002/cbdv.201700058



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