Base de dados : MEDLINE
Pesquisa : C07.550 [Categoria DeCS]
Referências encontradas : 4410 [refinar]
Mostrando: 1 .. 10   no formato [Detalhado]

página 1 de 441 ir para página                         

  1 / 4410 MEDLINE  
              next record last record
seleciona
para imprimir
Fotocópia
[PMID]:29217814
[Au] Autor:Anitha A; Delhi Kumar CG
[Ad] Endereço:Department of Pediatrics, JIPMER, Puducherry, India. dillikumar14@gmail.com.
[Ti] Título:An Uncommon Cause of Stridor in a Young Infant.
[So] Source:Indian Pediatr;54(11):976, 2017 11 15.
[Is] ISSN:0974-7559
[Cp] País de publicação:India
[La] Idioma:eng
[Mh] Termos MeSH primário: Cistos
Doenças Faríngeas
Sons Respiratórios/etiologia
[Mh] Termos MeSH secundário: Cistos/complicações
Cistos/diagnóstico por imagem
Cistos/patologia
Cistos/cirurgia
Feminino
Seres Humanos
Lactente
Recém-Nascido
Doenças Faríngeas/complicações
Doenças Faríngeas/diagnóstico por imagem
Doenças Faríngeas/patologia
Doenças Faríngeas/cirurgia
Faringe/diagnóstico por imagem
Faringe/patologia
Faringe/cirurgia
[Pt] Tipo de publicação:CASE REPORTS; LETTER
[Em] Mês de entrada:1803
[Cu] Atualização por classe:180301
[Lr] Data última revisão:
180301
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171209
[St] Status:MEDLINE


  2 / 4410 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:29262461
[Au] Autor:Li WP; Xu HM; Zhao LM; Li XY
[Ad] Endereço:Department of Otorhinolaryngology Head and Neck Surgery, Shanghai Children's Hospital, Shanghai Jiao Tong University; Shanghai 200062, China.
[Ti] Título:[Advances in endoscopic treatment of congenital pyriform sinus fistula in children].
[So] Source:Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi;52(12):952-955, 2017 Dec 07.
[Is] ISSN:1673-0860
[Cp] País de publicação:China
[La] Idioma:chi
[Ab] Resumo:Pyriform sinus fistula is a rare clinical disease, often with recurrent acute suppurative thyroiditis or neck infection in children.The traditional method treatment is complete resection of the fistula with or without hemithyroidectomy in external cervical surgical approach, but in recent years, minimally invasive endoscopic occlusion of the internal opening for the treatment of pyriform sinus fistula is performed in many hospitals, including electrocautery, chemocautery, laser cauterization, biocauterization, and suture closure. Literatures about endoscopic management of pyriform sinus fistula in children are reviewed and various surgical methods, complications and success rate are evaluated.
[Mh] Termos MeSH primário: Endoscopia/métodos
Doenças Faríngeas/terapia
Seio Piriforme
Fístula do Sistema Respiratório/terapia
[Mh] Termos MeSH secundário: Cauterização
Criança
Eletrocoagulação
Feminino
Seres Humanos
Terapia a Laser
Masculino
Pescoço/cirurgia
Doenças Faríngeas/congênito
Recidiva
Fístula do Sistema Respiratório/congênito
Estudos Retrospectivos
Tireoidectomia
Tireoidite Supurativa/etiologia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180207
[Lr] Data última revisão:
180207
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171221
[St] Status:MEDLINE
[do] DOI:10.3760/cma.j.issn.1673-0860.2017.12.019


  3 / 4410 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:29049225
[Au] Autor:Wu J; Gu M; Chen S; Chen W; Ni K; Xu H; Li X
[Ad] Endereço:Department of Otolaryngology and Head and Neck Surgery, Shanghai Children's Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China.
[Ti] Título:Factors related to pediatric obstructive sleep apnea-hypopnea syndrome in children with attention deficit hyperactivity disorder in different age groups.
[So] Source:Medicine (Baltimore);96(42):e8281, 2017 Oct.
[Is] ISSN:1536-5964
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:This study aimed to retrospectively investigate the factors related to pediatric obstructive sleep apnea-hypopnea syndrome (OSAHS) with attention deficit hyperactivity disorder (ADHD) in children younger than 6 years and those older than 6 years.A total of 437 children who were hospitalized due to OSAHS between January 2014 and December 2014 were retrospectively reviewed. The children were further divided into OSAHS group and OSAHS + ADHD group. The general characteristics, OSA-18 quality of life, intention-hyperactivity score, and polysomnographic parameters (apnea-hypopnea index and the lowest oxygen saturation) were collected and compared between groups.There were 298 boys and 139 girls with the male to female ratio of 2.14:1. ADHD was found in 146 children including 105 boys and 41 girls with the male to female ratio of 2.56:1. Of these children, 31.62% and 35.46% had concomitant ADHD in children aged 4 to 5 years and those aged 6 to 11 years, respectively. In children aged 4 to 5 years, the incidence of allergic rhinitis was significantly higher (P = .016) and the adenoid hypertrophy was more severe (P = .001) in those with concomitant ADHD. In children aged 6 to 11 years, the tonsil hypertrophy was more severe in those with concomitant ADHD (P = .019). In children with concomitant ADHD, OSA-18 score was higher than in those with OSAHS alone (P < .001). Higher frequency of respiratory events (P < .001) and more severe hypoxia (P < .001) were found in children with concomitant ADHD than in those with OSAHS alone.As high as 30% of OSAHS children have concomitant ADHD, and the incidence of ADHD in OSAHS children is increasing over age. Boys are more likely to develop OSAHS and incidence of ADHD in OSAHS boys is higher than in OSAHS girls. In addition, risk factors of ADHD also vary between age groups. The ADHD is related to the severity of allergic rhinitis and adenoid hypertrophy in children aged 4 to 5 years, and to the severity of tonsil hypertrophy in children aged 6 to 11 years. Hypoxia may be an important factor causing ADHD. OSAHS should be treated as early as possible to reduce the incidence of ADHD in children.
[Mh] Termos MeSH primário: Transtorno do Deficit de Atenção com Hiperatividade/epidemiologia
Apneia Obstrutiva do Sono/epidemiologia
[Mh] Termos MeSH secundário: Tonsila Faríngea/patologia
Fatores Etários
Criança
Pré-Escolar
Feminino
Seres Humanos
Masculino
Tonsila Palatina/patologia
Doenças Faríngeas/epidemiologia
Doenças Faríngeas/patologia
Polissonografia
Qualidade de Vida
Estudos Retrospectivos
Rinite Alérgica/epidemiologia
Índice de Gravidade de Doença
Fatores Sexuais
[Pt] Tipo de publicação:JOURNAL ARTICLE; OBSERVATIONAL STUDY
[Em] Mês de entrada:1711
[Cu] Atualização por classe:171122
[Lr] Data última revisão:
171122
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:171020
[St] Status:MEDLINE
[do] DOI:10.1097/MD.0000000000008281


  4 / 4410 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:28964284
[Au] Autor:Marchica C; Zawawi F; Daniel SJ
[Ad] Endereço:Department of Pediatric Otolaryngology Head and Neck Surgery, McGill University Health Center, Montreal Children's Hospital, Montreal, Quebec, Canada.
[Ti] Título:Management of cricopharyngeal achalasia in an 8-month child using endoscopic cricopharyngeal myotomy.
[So] Source:Int J Pediatr Otorhinolaryngol;101:137-140, 2017 Oct.
[Is] ISSN:1872-8464
[Cp] País de publicação:Ireland
[La] Idioma:eng
[Ab] Resumo:A term baby was transferred to our tertiary care center with desaturations and inability to manage upper airway secretions. Rigid bronchoscopy and swallowing study revealed cricopharyngeal (CP) achalasia. A gastrostomy tube insertion and Botulinum Toxin-A injection were performed at 6 weeks of age. Improvement of symptoms was observed, however were short-lived requiring recurrent injections. Given the symptom severity, at 8 months, a successful endoscopic CP myotomy was performed. Patient was able to tolerate oral feeds as early as 2 months post-operatively. This is the youngest patient, to our knowledge, treated with endoscopic CP myotomy. Intraoperative pictures and video are presented.
[Mh] Termos MeSH primário: Toxinas Botulínicas Tipo A/uso terapêutico
Cartilagem Cricoide/cirurgia
Endoscopia/métodos
Acalasia Esofágica/cirurgia
Músculos Faríngeos/cirurgia
[Mh] Termos MeSH secundário: Deglutição
Feminino
Seres Humanos
Lactente
Masculino
Doenças Faríngeas/diagnóstico
Doenças Faríngeas/cirurgia
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Nm] Nome de substância:
EC 3.4.24.69 (Botulinum Toxins, Type A)
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171023
[Lr] Data última revisão:
171023
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171002
[St] Status:MEDLINE


  5 / 4410 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:28766977
[Au] Autor:Tam K; Jeffery C; Sung CK
[Ad] Endereço:1 Stanford University School of Medicine, Stanford, California, USA.
[Ti] Título:Surgical Management of Supraglottic Stenosis Using Intubationless Optiflow.
[So] Source:Ann Otol Rhinol Laryngol;126(9):669-672, 2017 Sep.
[Is] ISSN:1943-572X
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:OBJECTIVE: Airway management during endoscopic surgical treatment of supraglottic and pharyngeal stenosis is often challenging and can be accomplished by various means, including tracheostomy, jet ventilation, or direct laryngoscopy. We describe CO laser excision of supraglottic-pharyngeal stenosis using intubationless Optiflow high-flow nasal cannula (HFNC). METHODS: A 55-year-old male presented with dyspnea and dysphagia secondary to severe supraglottic-pharyngeal stenosis in the setting of previous chemoradiation for a T0N2aM0 squamous cell carcinoma. Laryngoscopy revealed severe supraglottic-pharyngeal stenosis with tethering of the epiglottis to the lateral pharyngeal walls. Optiflow HFNC was used to deliver 70 L/min of oxygen. After anesthetic induction, CO laser microlaryngoscopy was utilized to release scar tissue along the lateral epiglottic border, opening up the supraglottic airway sufficiently for endotracheal intubation and further laser resection. RESULTS: Airway management with Optiflow HFNC allowed initial endoscopic surgical access, partial stenotic release, and intubation. From anesthetic induction to intubation, the patient remained apneic for 26 minutes. The patient's stenosis was successfully addressed, and 10-month follow-up demonstrated stable patency of the airway. CONCLUSION: Optiflow is an important new tool in the management of severe supraglottic stenosis. It provides sufficient oxygenation to perform extended apneic surgery and improves endoscopic surgical access in a limited airway.
[Mh] Termos MeSH primário: Obstrução das Vias Respiratórias/cirurgia
Cânula
Transtornos de Deglutição/cirurgia
Epiglote/cirurgia
Laringoscopia/métodos
Terapia a Laser/métodos
Oxigenoterapia/instrumentação
Doenças Faríngeas/cirurgia
[Mh] Termos MeSH secundário: Obstrução das Vias Respiratórias/etiologia
Carcinoma de Células Escamosas/terapia
Quimiorradioterapia/efeitos adversos
Constrição Patológica/etiologia
Constrição Patológica/cirurgia
Transtornos de Deglutição/etiologia
Neoplasias de Cabeça e Pescoço/terapia
Seres Humanos
Intubação Intratraqueal
Lasers de Gás/uso terapêutico
Masculino
Meia-Idade
Oxigenoterapia/métodos
Doenças Faríngeas/etiologia
Neoplasias Faríngeas/terapia
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Em] Mês de entrada:1708
[Cu] Atualização por classe:170821
[Lr] Data última revisão:
170821
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:170803
[St] Status:MEDLINE
[do] DOI:10.1177/0003489417720220


  6 / 4410 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:28766955
[Au] Autor:Mei J; Huang Z; Wu K; Zhao Y; Yang J; Liu Y
[Ad] Endereço:1 Department of Otorhinolaryngology, Head and Neck Surgery, the First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China.
[Ti] Título:Risk Factors of Stomal Recurrence After Laryngectomy: A Systematic Review and Meta-analysis.
[So] Source:Ann Otol Rhinol Laryngol;126(9):654-668, 2017 Sep.
[Is] ISSN:1943-572X
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:OBJECTIVE: We wished to investigate the risk factors for stoma recurrence following laryngectomy. METHODS: PubMed, Cochrane Library, and Embase were searched to identify primary research studies published between January 1, 1967, and October 31, 2016. We only included observational epidemiological studies and used risk ratios (RRs) and 95% confidence intervals (CI) to summarize the primary risk factors associated with recurrence following laryngectomy. RESULTS: A total of 44 articles, including 11 928 patients, were included in the current meta-analysis. The pooled estimates of the stomal recurrence rate and the local recurrence rate following laryngectomy were 6.60% (95% CI, 5.40-7.90) and 19.40% (95% CI, 14.00%-24.80%), respectively. For stomal recurrence, we confirmed a series of earlier identified factors, including tumor site, prior tracheotomy, tracheotomy timing, T-classification, lymph node metastases, postoperative pharyngoperistomal fistula, and a positive surgical margin. For local recurrence, postoperative radiotherapy, overexpression of p53, and overexpression of p21 were significant, while preoperative tracheostomy and postoperative pharyngoperistomal fistula had an unexpectedly low impact on risk. CONCLUSION: This study has confirmed a series of earlier identified factors for stomal recurrence and local recurrence following laryngectomy. Our results will provide important insights for clinical practice.
[Mh] Termos MeSH primário: Neoplasias Laríngeas/cirurgia
Laringectomia
Recidiva Local de Neoplasia/epidemiologia
Estomas Cirúrgicos/patologia
Traqueostomia
[Mh] Termos MeSH secundário: Inibidor de Quinase Dependente de Ciclina p21/metabolismo
Seres Humanos
Neoplasias Laríngeas/metabolismo
Neoplasias Laríngeas/patologia
Linfonodos/patologia
Margens de Excisão
Recidiva Local de Neoplasia/patologia
Estadiamento de Neoplasias
Doenças Faríngeas/epidemiologia
Radioterapia Adjuvante
Fístula do Sistema Respiratório/epidemiologia
Fatores de Risco
Traqueostomia/estatística & dados numéricos
Traqueotomia/estatística & dados numéricos
Proteína Supressora de Tumor p53/metabolismo
[Pt] Tipo de publicação:JOURNAL ARTICLE; META-ANALYSIS; REVIEW
[Nm] Nome de substância:
0 (CDKN1A protein, human); 0 (Cyclin-Dependent Kinase Inhibitor p21); 0 (TP53 protein, human); 0 (Tumor Suppressor Protein p53)
[Em] Mês de entrada:1708
[Cu] Atualização por classe:170821
[Lr] Data última revisão:
170821
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:170803
[St] Status:MEDLINE
[do] DOI:10.1177/0003489417720221


  7 / 4410 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:28728872
[Au] Autor:Ciccarese G; Broccolo F; Rebora A; Parodi A; Drago F
[Ad] Endereço:DISSAL Department of Dermatology, IRCCS AOU San Martino-IST, Genoa, Italy. Electronic address: giuliaciccarese@libero.it.
[Ti] Título:Oropharyngeal lesions in pityriasis rosea.
[So] Source:J Am Acad Dermatol;77(5):833-837.e4, 2017 Nov.
[Is] ISSN:1097-6787
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Pityriasis rosea (PR) is an exanthematous disease associated with the endogenous systemic reactivation of human herpesvirus-6 (HHV-6) and human herpesvirus-7 (HHV-7). Oropharyngeal lesions may be associated with the exanthema, but anecdotal evidence suggests that few dermatologists are aware of their occurrence. OBJECTIVE: Classifying oropharyngeal lesions in PR, establishing their prevalence, and assessing their possible association with different PR forms. METHODS: The records of all PR cases diagnosed in the Dermatology Clinic of Genoa University between 2003 and 2016 were retrospectively reviewed to examine sex and age of the patients, PR type, presence of enanthema, systemic symptoms, specific anti-HHV-6 and or HHV-7 serology, and HHV-6 and/or HHV-7 DNA loads. RESULTS: The oropharyngeal mucosa was carefully examined in 527 patients with PR. Painless oropharyngeal lesions were observed in 149 patients with PR (28%) and classified as erythematomacular, macular and papular, erythematovesicular, and petechial lesions. The petechial and macular and papular patterns were those most frequently observed. There was no statistically significant difference in the levels of HHV-6 and HHV-7 viremia in the plasma of patients with enanthema and those without. LIMITATIONS: Because this was a retrospective study, biopsies on mucosal lesions were not performed. CONCLUSION: Our findings showed that enanthemas are frequently associated with forms of PR different from the classic form.
[Mh] Termos MeSH primário: Doenças da Boca/epidemiologia
Doenças Faríngeas/virologia
Pitiríase Rósea/epidemiologia
Pitiríase Rósea/virologia
[Mh] Termos MeSH secundário: Adulto
Distribuição por Idade
Criança
Pré-Escolar
Estudos de Coortes
Feminino
Herpesvirus Humano 6/isolamento & purificação
Herpesvirus Humano 7/isolamento & purificação
Seres Humanos
Masculino
Meia-Idade
Doenças da Boca/fisiopatologia
Doenças da Boca/virologia
Mucosa Bucal/fisiopatologia
Mucosa Bucal/virologia
Doenças Faríngeas/epidemiologia
Doenças Faríngeas/fisiopatologia
Faringe/fisiopatologia
Faringe/virologia
Pitiríase Rósea/patologia
Prevalência
Prognóstico
Sistema de Registros
Estudos Retrospectivos
Medição de Risco
Distribuição por Sexo
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1711
[Cu] Atualização por classe:171102
[Lr] Data última revisão:
171102
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170722
[St] Status:MEDLINE


  8 / 4410 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:28659133
[Au] Autor:Chow EPF; Walker S; Hocking JS; Bradshaw CS; Chen MY; Tabrizi SN; Howden BP; Law MG; Maddaford K; Read TRH; Lewis DA; Whiley DM; Zhang L; Grulich AE; Kaldor JM; Cornelisse VJ; Phillips S; Donovan B; McNulty AM; Templeton DJ; Roth N; Moore R; Fairley CK
[Ad] Endereço:Melbourne Sexual Health Centre, Alfred Health, 580 Swanston Street, Carlton, VIC, 3053, Australia. Echow@mshc.org.au.
[Ti] Título:A multicentre double-blind randomised controlled trial evaluating the efficacy of daily use of antibacterial mouthwash against oropharyngeal gonorrhoea among men who have sex with men: the OMEGA (Oral Mouthwash use to Eradicate GonorrhoeA) study protocol.
[So] Source:BMC Infect Dis;17(1):456, 2017 Jun 28.
[Is] ISSN:1471-2334
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Gonorrhoea is one of the most common sexually transmissible infections in men who have sex with men (MSM). Gonorrhoea rates have increased substantially in recent years. There is concern that increasing gonorrhoea prevalence will increase the likelihood of worsening antibiotic resistance in Neisseria gonorrhoeae. A recent randomised controlled trial (RCT) demonstrated that a single-dose of mouthwash has an inhibitory effect against oropharyngeal gonorrhoea. We are conducting the first RCT to evaluate whether daily use of mouthwash could reduce the risk of acquiring oropharyngeal gonorrhoea. METHODS/DESIGN: The OMEGA (Oral Mouthwash use to Eradicate GonorrhoeA) study is a double-blind RCT and will be conducted at several sexual health clinics and high caseload General Practice (GP) clinics in Melbourne and Sydney, Australia. A total of 504 MSM attending the participating sites will be recruited. Participants will be randomised to either using 'Study mouthwash A' or 'Study mouthwash B' for 12 weeks. Study mouthwash A was inhibitory against N. gonorrhoeae in vitro, whereas study mouthwash B was not. Participants will be instructed to rinse and gargle the study mouthwash for 60 seconds every day. The primary outcome is the proportion of participants with oropharyngeal gonorrhoea detected by nucleic acid amplification test by 12 weeks. DISCUSSION: The results from this trial may provide a novel way to reduce gonorrhoea prevalence and transmission without the use of antibiotics that may be associated with development of resistance. If shown to be effective, the widespread use of mouthwash will reduce the prevalence of oropharyngeal gonorrhoea, which plays key role in driving the emergence of gonococcal antimicrobial resistance through DNA exchange with oral commensal bacteria. The anticipated net effect will be interruption of onward transmission of N. gonorrhoeae within high density sexual networks within MSM populations. TRIAL REGISTRATION: Australian New Zealand Clinical Trials Registry ACTRN12616000247471 , registered on 23rd February 2016.
[Mh] Termos MeSH primário: Antibacterianos/farmacologia
Gonorreia/prevenção & controle
Homossexualidade Masculina
Antissépticos Bucais/farmacologia
Doenças Sexualmente Transmissíveis/prevenção & controle
[Mh] Termos MeSH secundário: Adulto
Antibacterianos/administração & dosagem
Antibacterianos/uso terapêutico
Protocolos Clínicos
Método Duplo-Cego
Gonorreia/microbiologia
Gonorreia/transmissão
Seres Humanos
Masculino
Neisseria gonorrhoeae/efeitos dos fármacos
Neisseria gonorrhoeae/patogenicidade
Doenças Faríngeas/microbiologia
Infecções Respiratórias/tratamento farmacológico
Doenças Sexualmente Transmissíveis/microbiologia
[Pt] Tipo de publicação:JOURNAL ARTICLE; MULTICENTER STUDY; RANDOMIZED CONTROLLED TRIAL
[Nm] Nome de substância:
0 (Anti-Bacterial Agents); 0 (Mouthwashes)
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170925
[Lr] Data última revisão:
170925
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170630
[St] Status:MEDLINE
[do] DOI:10.1186/s12879-017-2541-3


  9 / 4410 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:28520896
[Au] Autor:Partington EJ; Moore LS; Kahmke R; Warram JM; Carroll W; Rosenthal EL; Greene BJ
[Ad] Endereço:Department of Otolaryngology, University of Alabama at Birmingham, Birmingham.
[Ti] Título:Laser-Assisted Indocyanine Green Dye Angiography for Postoperative Fistulas After Salvage Laryngectomy.
[So] Source:JAMA Otolaryngol Head Neck Surg;143(8):775-781, 2017 Aug 01.
[Is] ISSN:2168-619X
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Importance: Pharyngocutaneous fistula formation is an unfortunate complication after salvage laryngectomy for head and neck cancer that is difficult to anticipate and related to a variety of factors, including the viability of native pharyngeal mucosa. Objective: To examine whether noninvasive angiography with indocyanine green (ICG) dye can be used to evaluate native pharyngeal vascularity to anticipate pharyngocutaneous fistula development. Design, Setting, and Participants: This cohort study included 37 patients enrolled from June 1, 2013, to June 1, 2016, and follow-up was for at least 1 month postoperatively. The study was performed at the University of Alabama at Birmingham, a tertiary care center. Included patients were those undergoing salvage total laryngectomy who were previously treated with chemoradiotherapy or radiotherapy alone. Exposures: The ICG dye was injected intraoperatively, and laser-assisted vascular imaging was used to evaluate the native pharyngeal mucosa after the ablative procedure. The center of the native pharyngeal mucosa was used as the reference to compare with the peripheral mucosa, and the lowest mean ICG dye percentage of mucosal perfusion was recorded for each patient. Main Outcomes and Measures: The primary outcome was the formation of a postoperative fistula, which was assessed by clinical and radiographic assessment to test the hypothesis formulated before data collection. Results: A total of 37 patients were included (mean [SD] age, 62.3 [8.5] years; 32 [87%] male and 5 [14%] female); 20 had a history of chemoradiotherapy, and 17 had history of radiotherapy alone. Thirty-four patients (92%) had free flap reconstruction, and 3 had primary closure (8%). Ten patients (27%) developed a postoperative fistula. No significant difference was found in fistula rate between patients who underwent neck dissection and those who did not and patients previously treated with chemoradiotherapy and those treated with radiotherapy alone. A receiver operator characteristic curve was generated to determine the diagnostic performance of the lowest mean ICG dye percentage of mucosal perfusion determined by fluorescence imaging, which was found to be a threshold value of 26%. The area under the curve was 0.85 (95% CI, 0.73-0.97), which was significantly greater than the chance diagonal. The overall mean lowest ICG dye percentage of mucosal perfusion was 31.3%. The mean lowest ICG dye percentage of mucosal perfusion was 22.0% in the fistula group vs 34.9% in the nonfistula group (absolute difference, 12.9%; 95% CI, 5.1%-21.7%). Conclusions and Relevance: Patients who developed postoperative fistulas had lower mucosal perfusion as detected by ICG dye angiography when compared with patients who did not develop fistulas.
[Mh] Termos MeSH primário: Angiografia/métodos
Fístula Cutânea/diagnóstico por imagem
Neoplasias de Cabeça e Pescoço/cirurgia
Doenças Faríngeas/diagnóstico por imagem
Faringe/irrigação sanguínea
Complicações Pós-Operatórias/diagnóstico por imagem
[Mh] Termos MeSH secundário: Alabama
Feminino
Seres Humanos
Verde de Indocianina
Laringectomia/métodos
Lasers
Masculino
Meia-Idade
Terapia de Salvação
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
IX6J1063HV (Indocyanine Green)
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170911
[Lr] Data última revisão:
170911
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:170519
[St] Status:MEDLINE
[do] DOI:10.1001/jamaoto.2017.0187


  10 / 4410 MEDLINE  
              first record previous record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:28514359
[Au] Autor:Yastremsky AP; Izvin AI
[Ad] Endereço:Department of ENT Diseases, Tyumen State Medical University, Tyumen, Russia, 625023.
[Ti] Título:[The mathematical approaches to differential diagnostics of acute pharyngeal diseases].
[Ti] Título:Matematicheskie podkhody k differentsial'noi diagnostike ostrykh zabolevanii glotki..
[So] Source:Vestn Otorinolaringol;82(2):24-28, 2017.
[Is] ISSN:0042-4668
[Cp] País de publicação:Russia (Federation)
[La] Idioma:rus
[Ab] Resumo:The objective of the present study was to elaborate the program for differential diagnostics of acute pharyngeal diseases based on the 'ENT-Neuro' artificial neuronal network. The study group was formed by means of sampling patients with acute pharyngeal diseases from a set of case histories of the subjects presenting with acute inflammatory diseases. The data thus obtained were employed to develop the expert system to support the decision making process with the use of the 'ENT-Neuro' artificial neuronal network that allows to carry out diagnostics of various inflammatory diseases of the pharynx including the following nosological entities: paratonsillitis, parapharyngitis, acute tonsillitis, and acute pharyngitis, with the minimal probability of erroneous diagnosis (4%). The proposed expert system makes it possible to choose the optimal treatment strategy for the management of various pharyngeal diseases taking into consideration the severity of a concrete pathology and thereby to reduce to a minimum the risk of the related complications.
[Mh] Termos MeSH primário: Redes Neurais (Computação)
Doenças Faríngeas
[Mh] Termos MeSH secundário: Doença Aguda
Adulto
Diagnóstico Diferencial
Gerenciamento Clínico
Feminino
Seres Humanos
Masculino
Seleção de Pacientes
Doenças Faríngeas/diagnóstico
Doenças Faríngeas/terapia
Índice de Gravidade de Doença
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1707
[Cu] Atualização por classe:170713
[Lr] Data última revisão:
170713
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170518
[St] Status:MEDLINE
[do] DOI:10.17116/otorino201782224-28



página 1 de 441 ir para página                         
   


Refinar a pesquisa
  Base de dados : MEDLINE Formulário avançado   

    Pesquisar no campo  
1  
2
3
 
           



Search engine: iAH v2.6 powered by WWWISIS

BIREME/OPAS/OMS - Centro Latino-Americano e do Caribe de Informação em Ciências da Saúde