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[PMID]:28459246
[Au] Autor:Todd M; Brackett W; Romero M
[Ad] Endereço:Instructor, Oral Rehabilitation Department, Dental College of Georgia at Augusta University, Augusta, Georgia.
[Ti] Título:Correction of a Single Discolored Anterior Tooth Due to Internal Resorption: A Clinical Report.
[So] Source:Compend Contin Educ Dent;38(5):e13-e16, 2017 May.
[Is] ISSN:2158-1797
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:For patients with a single discolored tooth who desire to have it lightened, a thorough examination and radiographic analysis need to be performed prior to initiating any bleaching treatment so that the cause of the discoloration can be determined. Underlying pathology, such as internal resorption, is often asymptomatic and difficult to diagnose and if left untreated could result in tooth loss. This article describes a case of a patient with a discolored maxillary central incisor resulting from internal resorption and the subsequent endodontic and bleaching therapy performed to resolve the pathology and achieve an acceptable esthetic result.
[Mh] Termos MeSH primário: Clareamento Dental/métodos
Descoloração de Dente/terapia
[Mh] Termos MeSH secundário: Adulto
Feminino
Seres Humanos
Incisivo
Maxila
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Em] Mês de entrada:1803
[Cu] Atualização por classe:180308
[Lr] Data última revisão:
180308
[Sb] Subgrupo de revista:D
[Da] Data de entrada para processamento:170502
[St] Status:MEDLINE


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[PMID]:28747157
[Au] Autor:Batista MJ; Lawrence HP; Sousa MDLR
[Ad] Endereço:Community Health, Jundiai Medical School, Francisco Telles, 250, P.O. Box1295, Jundiaí, SP, 13202-550, Brazil. mariliajbatista@yahoo.com.br.
[Ti] Título:Oral health literacy and oral health outcomes in an adult population in Brazil.
[So] Source:BMC Public Health;18(1):60, 2017 07 26.
[Is] ISSN:1471-2458
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: To investigate the association between critical and communicative oral health literacy (OHL) and oral health outcomes (status, oral health-related quality of life and practices) in adults. METHODS: This cross-sectional study examined a household probability sample of 248 adults, representing 149,635 residents (20-64 years old) in Piracicaba-SP, Brazil. Clinical oral health and socioeconomic and demographic data, as well as data on oral health-related quality of life (OHIP-14) and health practices were collected. The oral examinations were carried out in the participants' homes, using the World Health Organization criteria for oral diseases. The critical and communicative OHL instrument was the primary independent variable, and it was measured using five Likert items that were dichotomized as 'high' ('agree' and 'strongly agree' responses for the 5 items) and 'low' OHL. Binary and multinomial logistic regressions were performed on each outcome (oral health status and practices), controlling for age, sex and socioeconomic status (SES). RESULTS: Approximately 71.5% presented low OHL. When adjusted for age and sex (first model) low OHL was associated with untreated caries (Odds Ratio = 1.92, 95% Confidence Interval = 1.07-3.45), tooth brushing <3 times a day (OR = 2.00, 1.11-3.62) and irregular tooth flossing (OR = 2.17, 1.24-3.80). After SES inclusion in the first model, significant associations were found for low OHL when the outcomes were: presence of biofilm (OR = 1.83, 1.08-3.33), dental care for emergency only (OR = 2.24, 1.24-4.04) and prevalence of oral health impact on quality of life (OR = 2.06, 1.15-3.69). CONCLUSION: Adjusting for age, sex and SES, OHL is related to a risk factor (biofilm) and a consequence of poor oral health (emergency dental visits) and can interfere with the impact of oral diseases on quality of life. As low OHL can be modified, the results support oral health promotion strategies directed at improving critical and communicative oral health literacy in adult populations.
[Mh] Termos MeSH primário: Alfabetização em Saúde/estatística & dados numéricos
Doenças da Boca/epidemiologia
Saúde Bucal/estatística & dados numéricos
Qualidade de Vida
Odontopatias/epidemiologia
[Mh] Termos MeSH secundário: Adulto
Brasil/epidemiologia
Estudos Transversais
Feminino
Seres Humanos
Masculino
Meia-Idade
Higiene Bucal/estatística & dados numéricos
Prevalência
Fatores de Risco
Fatores Socioeconômicos
Descoloração de Dente
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180220
[Lr] Data última revisão:
180220
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170728
[St] Status:MEDLINE
[do] DOI:10.1186/s12889-017-4443-0


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[PMID]:29231682
[Au] Autor:Wynne T; Wynne WPD
[Ti] Título:Creating a More Youthful Smile.
[So] Source:Dent Today;36(5):77-9, 2017 May.
[Is] ISSN:8750-2186
[Cp] País de publicação:United States
[La] Idioma:eng
[Mh] Termos MeSH primário: Restauração Dentária Permanente/métodos
Estética Dentária
Má Oclusão/terapia
Sorriso
Descoloração de Dente/terapia
Desgaste dos Dentes/terapia
[Mh] Termos MeSH secundário: Feminino
Seres Humanos
Meia-Idade
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Em] Mês de entrada:1801
[Cu] Atualização por classe:180115
[Lr] Data última revisão:
180115
[Sb] Subgrupo de revista:D
[Da] Data de entrada para processamento:171213
[St] Status:MEDLINE


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[PMID]:29231671
[Au] Autor:Kirtley GE
[Ti] Título:The Aesthetic Zone Challenge.
[So] Source:Dent Today;36(6):74, 76-7, 2017 Jun.
[Is] ISSN:8750-2186
[Cp] País de publicação:United States
[La] Idioma:eng
[Mh] Termos MeSH primário: Implantação Dentária Endo-Óssea
Prótese Dentária Fixada por Implante
Estética Dentária
Incisivo/anormalidades
Maxila/anormalidades
[Mh] Termos MeSH secundário: Adolescente
Perda do Osso Alveolar
Feminino
Seres Humanos
Sorriso
Descoloração de Dente
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Em] Mês de entrada:1801
[Cu] Atualização por classe:180115
[Lr] Data última revisão:
180115
[Sb] Subgrupo de revista:D
[Da] Data de entrada para processamento:171213
[St] Status:MEDLINE


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[PMID]:29185302
[Au] Autor:Wynne T; Wynne WPD
[Ti] Título:Resolving Color Variation.
[So] Source:Dent Today;35(9):106, 108-9, 2016 Sep.
[Is] ISSN:8750-2186
[Cp] País de publicação:United States
[La] Idioma:eng
[Mh] Termos MeSH primário: Coroas
Facetas Dentárias
Estética Dentária
Descoloração de Dente/terapia
[Mh] Termos MeSH secundário: Seres Humanos
Masculino
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Em] Mês de entrada:1712
[Cu] Atualização por classe:171221
[Lr] Data última revisão:
171221
[Sb] Subgrupo de revista:D
[Da] Data de entrada para processamento:171201
[St] Status:MEDLINE


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Registro de Ensaios Clínicos
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[PMID]:28564557
[Au] Autor:Metz LM; Li DKB; Traboulsee AL; Duquette P; Eliasziw M; Cerchiaro G; Greenfield J; Riddehough A; Yeung M; Kremenchutzky M; Vorobeychik G; Freedman MS; Bhan V; Blevins G; Marriott JJ; Grand'Maison F; Lee L; Thibault M; Hill MD; Yong VW; Minocycline in MS Study Team
[Ad] Endereço:From the Cumming School of Medicine and the Hotchkiss Brain Institute, Calgary, AB (L.M.M., G.C., J.G., M.Y., M.D.H., V.W.Y.), the University of British Columbia, Vancouver (D.K.B.L., A.L.T., A.R.), the University of Montreal, Montreal (P.D.), Western University, London, ON (M.K.), Fraser Health MS
[Ti] Título:Trial of Minocycline in a Clinically Isolated Syndrome of Multiple Sclerosis.
[So] Source:N Engl J Med;376(22):2122-2133, 2017 06 01.
[Is] ISSN:1533-4406
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: On the basis of encouraging preliminary results, we conducted a randomized, controlled trial to determine whether minocycline reduces the risk of conversion from a first demyelinating event (also known as a clinically isolated syndrome) to multiple sclerosis. METHODS: During the period from January 2009 through July 2013, we randomly assigned participants who had had their first demyelinating symptoms within the previous 180 days to receive either 100 mg of minocycline, administered orally twice daily, or placebo. Administration of minocycline or placebo was continued until a diagnosis of multiple sclerosis was established or until 24 months after randomization, whichever came first. The primary outcome was conversion to multiple sclerosis (diagnosed on the basis of the 2005 McDonald criteria) within 6 months after randomization. Secondary outcomes included conversion to multiple sclerosis within 24 months after randomization and changes on magnetic resonance imaging (MRI) at 6 months and 24 months (change in lesion volume on T -weighted MRI, cumulative number of new lesions enhanced on T -weighted MRI ["enhancing lesions"], and cumulative combined number of unique lesions [new enhancing lesions on T -weighted MRI plus new and newly enlarged lesions on T -weighted MRI]). RESULTS: A total of 142 eligible participants underwent randomization at 12 Canadian multiple sclerosis clinics; 72 participants were assigned to the minocycline group and 70 to the placebo group. The mean age of the participants was 35.8 years, and 68.3% were women. The unadjusted risk of conversion to multiple sclerosis within 6 months after randomization was 61.0% in the placebo group and 33.4% in the minocycline group, a difference of 27.6 percentage points (95% confidence interval [CI], 11.4 to 43.9; P=0.001). After adjustment for the number of enhancing lesions at baseline, the difference in the risk of conversion to multiple sclerosis within 6 months after randomization was 18.5 percentage points (95% CI, 3.7 to 33.3; P=0.01); the unadjusted risk difference was not significant at the 24-month secondary outcome time point (P=0.06). All secondary MRI outcomes favored minocycline over placebo at 6 months but not at 24 months. Trial withdrawals and adverse events of rash, dizziness, and dental discoloration were more frequent among participants who received minocycline than among those who received placebo. CONCLUSIONS: The risk of conversion from a clinically isolated syndrome to multiple sclerosis was significantly lower with minocycline than with placebo over 6 months but not over 24 months. (Funded by the Multiple Sclerosis Society of Canada; ClinicalTrials.gov number, NCT00666887 .).
[Mh] Termos MeSH primário: Antibacterianos/uso terapêutico
Doenças Desmielinizantes/tratamento farmacológico
Minociclina/uso terapêutico
Esclerose Múltipla/prevenção & controle
[Mh] Termos MeSH secundário: Análise Atuarial
Administração Oral
Adulto
Antibacterianos/efeitos adversos
Progressão da Doença
Tontura/induzido quimicamente
Método Duplo-Cego
Exantema/induzido quimicamente
Feminino
Seres Humanos
Análise de Intenção de Tratamento
Tábuas de Vida
Imagem por Ressonância Magnética
Masculino
Meia-Idade
Minociclina/efeitos adversos
Esclerose Múltipla/diagnóstico por imagem
Risco
Descoloração de Dente/induzido quimicamente
[Pt] Tipo de publicação:COMPARATIVE STUDY; JOURNAL ARTICLE; MULTICENTER STUDY; RANDOMIZED CONTROLLED TRIAL
[Nm] Nome de substância:
0 (Anti-Bacterial Agents); FYY3R43WGO (Minocycline)
[Em] Mês de entrada:1706
[Cu] Atualização por classe:170828
[Lr] Data última revisão:
170828
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:170601
[Cl] Clinical Trial:ClinicalTrial
[St] Status:MEDLINE
[do] DOI:10.1056/NEJMoa1608889


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Texto completo SciELO Brasil
[PMID]:28403365
[Au] Autor:Santos LG; Felippe WT; Souza BD; Konrath AC; Cordeiro MM; Felippe MC
[Ad] Endereço:Universidade Federal de Santa Catarina, Departamento de Odontologia, Florianópolis, Santa Catarina, Brasil.
[Ti] Título:Crown discoloration promoted by materials used in regenerative endodontic procedures and effect of dental bleaching: spectrophotometric analysis.
[So] Source:J Appl Oral Sci;25(2):234-242, 2017 Mar-Apr.
[Is] ISSN:1678-7765
[Cp] País de publicação:Brazil
[La] Idioma:eng
[Ab] Resumo:Objectives: To assess tooth crown's color after intracanal treatment with triple antibiotic paste (TAP) or calcium hydroxide (CH); cervical sealing with glass ionomer cement (GIC) or mineral trioxide aggregate (MTA); and bleaching with carbamide peroxide. Material and Methods: After pulp removal and color spectrophotometer measurement, 50 bovine incisors were divided into 4 experimental groups and one control (untreated). Experiments were performed in phases (Ph). Ph1: TAP (ciprofloxacin, metronidazole, minocycline), TAPM (ciprofloxacin, metronidazole, amoxicillin), DAP (ciprofloxacin, metronidazole), or CH treatment groups. After 1 and 3 days (d); 1, 2, 3 weeks (w); and 1, 2, 3 and 4 months (m), color was measured and medications were removed. Ph2: GIC or MTA cervical sealing, each using half of the specimens from each group. Color was assessed after 1d, 3d; 1w, 2w, 3w; 1m and 2m. Ph3: Two bleaching sessions, each followed by color measurement. Data were analyzed with ANOVA and post-hoc Holm-Sidak method. Results: Ph1: Specimens of TAP group presented higher color alteration (ΔE) mean than those of TAPM group. No significant difference was found among TAP or TAPM and CH, DAP or Control groups. Ph2: cervical sealing materials showed no influence on color alteration. Ph3: Different ΔE means (from different groups), prior to bleaching, became equivalent after one bleaching session. Conclusions: TAP induces higher color alteration than TAPM; color alteration increases over time; cervical sealing material has no influence on color alteration; and, dental bleaching was able to recover, at least partially, the tooth crown's color.
[Mh] Termos MeSH primário: Antibacterianos/química
Materiais Restauradores do Canal Radicular/química
Irrigantes do Canal Radicular/química
Tratamento do Canal Radicular/métodos
Clareadores Dentários/química
Coroa do Dente/efeitos dos fármacos
Descoloração de Dente/induzido quimicamente
[Mh] Termos MeSH secundário: Compostos de Alumínio/química
Animais
Compostos de Cálcio/química
Hidróxido de Cálcio/química
Bovinos
Combinação de Medicamentos
Cimentos de Ionômeros de Vidro/química
Teste de Materiais
Óxidos/química
Peróxidos/química
Pigmentação em Prótese
Valores de Referência
Reprodutibilidade dos Testes
Silicatos/química
Espectrofotometria
Fatores de Tempo
Clareamento Dental/métodos
Ureia/análogos & derivados
Ureia/química
[Pt] Tipo de publicação:EVALUATION STUDIES; JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Aluminum Compounds); 0 (Anti-Bacterial Agents); 0 (Calcium Compounds); 0 (Drug Combinations); 0 (Glass Ionomer Cements); 0 (Oxides); 0 (Peroxides); 0 (Root Canal Filling Materials); 0 (Root Canal Irrigants); 0 (Silicates); 0 (Tooth Bleaching Agents); 0 (mineral trioxide aggregate); 31PZ2VAU81 (carbamide peroxide); 8W8T17847W (Urea); PF5DZW74VN (Calcium Hydroxide)
[Em] Mês de entrada:1705
[Cu] Atualização por classe:170530
[Lr] Data última revisão:
170530
[Sb] Subgrupo de revista:D; IM
[Da] Data de entrada para processamento:170414
[St] Status:MEDLINE


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[PMID]:28362061
[Au] Autor:James P; Worthington HV; Parnell C; Harding M; Lamont T; Cheung A; Whelton H; Riley P
[Ad] Endereço:Oral Health Services Research Centre, Cork University Dental School and Hospital, Wilton, Cork, Ireland.
[Ti] Título:Chlorhexidine mouthrinse as an adjunctive treatment for gingival health.
[So] Source:Cochrane Database Syst Rev;3:CD008676, 2017 03 31.
[Is] ISSN:1469-493X
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Dental plaque associated gingivitis is a reversible inflammatory condition caused by accumulation and persistence of microbial biofilms (dental plaque) on the teeth. It is characterised by redness and swelling of the gingivae (gums) and a tendency for the gingivae to bleed easily. In susceptible individuals, gingivitis may lead to periodontitis and loss of the soft tissue and bony support for the tooth. It is thought that chlorhexidine mouthrinse may reduce the build-up of plaque thereby reducing gingivitis. OBJECTIVES: To assess the effectiveness of chlorhexidine mouthrinse used as an adjunct to mechanical oral hygiene procedures for the control of gingivitis and plaque compared to mechanical oral hygiene procedures alone or mechanical oral hygiene procedures plus placebo/control mouthrinse. Mechanical oral hygiene procedures were toothbrushing with/without the use of dental floss or interdental cleaning aids and could include professional tooth cleaning/periodontal treatment.To determine whether the effect of chlorhexidine mouthrinse is influenced by chlorhexidine concentration, or frequency of rinsing (once/day versus twice/day).To report and describe any adverse effects associated with chlorhexidine mouthrinse use from included trials. SEARCH METHODS: Cochrane Oral Health's Information Specialist searched the following databases: Cochrane Oral Health's Trials Register (to 28 September 2016); the Cochrane Central Register of Controlled Trials (CENTRAL; 2016, Issue 8) in the Cochrane Library (searched 28 September 2016); MEDLINE Ovid (1946 to 28 September 2016); Embase Ovid (1980 to 28 September 2016); and CINAHL EBSCO (Cumulative Index to Nursing and Allied Health Literature; 1937 to 28 September 2016). We searched ClinicalTrials.gov and the World Health Organization International Clinical Trials Registry Platform for ongoing trials. No restrictions were placed on the language or date of publication when searching the electronic databases. SELECTION CRITERIA: We included randomised controlled trials assessing the effects of chlorhexidine mouthrinse used as an adjunct to mechanical oral hygiene procedures for at least 4 weeks on gingivitis in children and adults. Mechanical oral hygiene procedures were toothbrushing with/without use of dental floss or interdental cleaning aids and could include professional tooth cleaning/periodontal treatment. We included trials where participants had gingivitis or periodontitis, where participants were healthy and where some or all participants had medical conditions or special care needs. DATA COLLECTION AND ANALYSIS: Two review authors independently screened the search results extracted data and assessed the risk of bias of the included studies. We attempted to contact study authors for missing data or clarification where feasible. For continuous outcomes, we used means and standard deviations to obtain the mean difference (MD) and 95% confidence interval (CI). We combined MDs where studies used the same scale and standardised mean differences (SMDs) where studies used different scales. For dichotomous outcomes, we reported risk ratios (RR) and 95% CIs. Due to anticipated heterogeneity we used random-effects models for all meta-analyses. MAIN RESULTS: We included 51 studies that analysed a total of 5345 participants. One study was assessed as being at unclear risk of bias, with the remaining 50 being at high risk of bias, however, this did not affect the quality assessments for gingivitis and plaque as we believe that further research is very unlikely to change our confidence in the estimate of effect. Gingivitis After 4 to 6 weeks of use, chlorhexidine mouthrinse reduced gingivitis (Gingival Index (GI) 0 to 3 scale) by 0.21 (95% CI 0.11 to 0.31) compared to placebo, control or no mouthrinse (10 trials, 805 participants with mild gingival inflammation (mean score 1 on the GI scale) analysed, high-quality evidence). A similar effect size was found for reducing gingivitis at 6 months. There were insufficient data to determine the reduction in gingivitis associated with chlorhexidine mouthrinse use in individuals with mean GI scores of 1.1 to 3 (moderate or severe levels of gingival inflammation). Plaque Plaque was measured by different indices and the SMD at 4 to 6 weeks was 1.45 (95% CI 1.00 to 1.90) standard deviations lower in the chlorhexidine group (12 trials, 950 participants analysed, high-quality evidence), indicating a large reduction in plaque. A similar large reduction was found for chlorhexidine mouthrinse use at 6 months. Extrinsic tooth staining There was a large increase in extrinsic tooth staining in participants using chlorhexidine mouthrinse at 4 to 6 weeks. The SMD was 1.07 (95% CI 0.80 to 1.34) standard deviations higher (eight trials, 415 participants analysed, moderate-quality evidence) in the chlorhexidine mouthrinse group. There was also a large increase in extrinsic tooth staining in participants using chlorhexidine mouthrinse at 7 to 12 weeks and 6 months. Calculus Results for the effect of chlorhexidine mouthrinse on calculus formation were inconclusive. Effect of concentration and frequency of rinsing There were insufficient data to determine whether there was a difference in effect for either chlorhexidine concentration or frequency of rinsing. Other adverse effects The adverse effects most commonly reported in the included studies were taste disturbance/alteration (reported in 11 studies), effects on the oral mucosa including soreness, irritation, mild desquamation and mucosal ulceration/erosions (reported in 13 studies) and a general burning sensation or a burning tongue or both (reported in nine studies). AUTHORS' CONCLUSIONS: There is high-quality evidence from studies that reported the Löe and Silness Gingival Index of a reduction in gingivitis in individuals with mild gingival inflammation on average (mean score of 1 on the 0 to 3 GI scale) that was not considered to be clinically relevant. There is high-quality evidence of a large reduction in dental plaque with chlorhexidine mouthrinse used as an adjunct to mechanical oral hygiene procedures for 4 to 6 weeks and 6 months. There is no evidence that one concentration of chlorhexidine rinse is more effective than another. There is insufficient evidence to determine the reduction in gingivitis associated with chlorhexidine mouthrinse use in individuals with mean GI scores of 1.1 to 3 indicating moderate or severe levels of gingival inflammation. Rinsing with chlorhexidine mouthrinse for 4 weeks or longer causes extrinsic tooth staining. In addition, other adverse effects such as calculus build up, transient taste disturbance and effects on the oral mucosa were reported in the included studies.
[Mh] Termos MeSH primário: Clorexidina/uso terapêutico
Placa Dentária/tratamento farmacológico
Gengivite/tratamento farmacológico
Antissépticos Bucais/uso terapêutico
[Mh] Termos MeSH secundário: Adolescente
Adulto
Idoso
Idoso de 80 Anos ou mais
Quimioterapia Adjuvante
Criança
Clorexidina/efeitos adversos
Placa Dentária/complicações
Índice de Placa Dentária
Profilaxia Dentária
Feminino
Gengivite/etiologia
Seres Humanos
Masculino
Meia-Idade
Antissépticos Bucais/efeitos adversos
Higiene Bucal
Viés de Publicação
Ensaios Clínicos Controlados Aleatórios como Assunto
Fatores de Tempo
Descoloração de Dente/induzido quimicamente
[Pt] Tipo de publicação:JOURNAL ARTICLE; META-ANALYSIS; REVIEW
[Nm] Nome de substância:
0 (Mouthwashes); R4KO0DY52L (Chlorhexidine)
[Em] Mês de entrada:1707
[Cu] Atualização por classe:171016
[Lr] Data última revisão:
171016
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170401
[St] Status:MEDLINE
[do] DOI:10.1002/14651858.CD008676.pub2


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[PMID]:28266718
[Au] Autor:Zhang F; Li Y; Xun Z; Zhang Q; Liu H; Chen F
[Ad] Endereço:Department of Pediatric Dentistry, Peking University School and Hospital of Stomatology, National Engineering Laboratory for Digital and Material Technology of Stomatology, Beijing Key Laboratory of Digital Stomatology, Beijing, China.
[Ti] Título:A preliminary study on the relationship between iron and black extrinsic tooth stain in children.
[So] Source:Lett Appl Microbiol;64(6):424-429, 2017 Jun.
[Is] ISSN:1472-765X
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Black extrinsic tooth stain, which has long troubled many people, is common among children and influences the aesthetics of teeth. The pigment was proposed to be a black insoluble ferric compound, but this is controversial. To determine whether iron exists in black stain, we collected 10 samples of black stain and 10 samples of plaque separately from children with and without black stain using sterile titanium implant curettes, and analysed the samples by inductively coupled plasma-mass spectrometry. Iron was present in both black stain and plaque, with concentrations ranging from 76·12 to 1116·88 µg g . The contents of iron in black stain were significantly higher than in plaque. Because bacteria may be involved in the aetiology of black stain, we assessed the functional genes of bacteria in black stain based on 16S rRNA gene sequencing results obtained using Phylogenetic Investigation of Communities by Reconstruction of Unobserved States. Of 253 Kyoto Encyclopedia of Gene and Genomes (KEGG) pathways tested, 56 differed in abundance between samples from children with and without black stain. Genera altered in black stain were related to many of the pathways. Some KEGG Orthology groups showed differences between black stain and plaque of control group were found to be related to iron. SIGNIFICANCE AND IMPACT OF THE STUDY: In this study, we have confirmed the existence of iron in black extrinsic tooth stain by ICP-MS. It was the first time the functional genes of bacteria in black stain were accessed and the genes associated with iron were found. These findings provided clues on the research of aetiology of black stain, which troubled millions of children. It also revealed the association between metabolic pathway of microbiota and oral phenomenon.
[Mh] Termos MeSH primário: Bactérias/metabolismo
Placa Dentária/microbiologia
Ferro/efeitos adversos
Microbiota
Descoloração de Dente/microbiologia
[Mh] Termos MeSH secundário: Bactérias/classificação
Bactérias/genética
Criança
Pré-Escolar
Biologia Computacional
DNA Bacteriano/química
DNA Bacteriano/genética
DNA Ribossômico/química
DNA Ribossômico/genética
Placa Dentária/etiologia
Feminino
Seres Humanos
Ferro/metabolismo
Masculino
Filogenia
RNA Ribossômico 16S/genética
Análise de Sequência de DNA
Descoloração de Dente/etiologia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (DNA, Bacterial); 0 (DNA, Ribosomal); 0 (RNA, Ribosomal, 16S); E1UOL152H7 (Iron)
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171003
[Lr] Data última revisão:
171003
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170308
[St] Status:MEDLINE
[do] DOI:10.1111/lam.12728


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[PMID]:28253587
[Au] Autor:Ren DF; Zhan KR; Chen XD; Xing WZ
[Ad] Endereço:Department of Prosthodontics, Dalian Stomatological Hospital, Dalian Liaoning 116021, China (Present address: Department of Pediatric Dentistry, Yantai Stomatological Hospital Affiliated to Binzhou Medical College, Yantai Shandong 264001, China).
[Ti] Título:[Effect of ceramic thickness and resin cement shades on final color of heat-pressed ceramic veneers].
[So] Source:Zhonghua Kou Qiang Yi Xue Za Zhi;52(2):109-113, 2017 Feb 09.
[Is] ISSN:1002-0098
[Cp] País de publicação:China
[La] Idioma:chi
[Ab] Resumo:To analyze the effect of ceramic materials thickness and resin cement shades on the final color of ceramic veneers in the discolored teeth, and to investigate the color agreement of try-in pastes to the corresponding resin cements. Sixty artificial maxillary central incisor teeth (C2 shade) were used to simulate the natural discolored teeth and prepared according to veneer tooth preparation protocol. Veneers of different thickness in the body region (0.50 and 0.75 mm) were fabricated using ceramic materials (LT A2 shade, IPS e.max Press). The ceramic veneer specimens were bonded to the artificial teeth using the 6 shades of resin cements (Variolink Veneer: shades of LV-3, LV-2, HV+3; RelyX™ Veneer: shades of TR, A3, WO) ( 5). A clinical spectrophotometer was used to measure the color parameters of ceramic veneers at the cervical, body and incisal regions. Color changes of veneers before and after cementation were calculated and registered as ΔE1, and the changes between try-in paste and the corresponding resin cements were registered as ΔE2. Three-way ANOVA indicated that ΔE1 and ΔE2 values were significantly affected by the ceramic thickness, resin cement shades and measuring regions ( 0.05). The ΔE1 values of six shades ranged from 0.59-8.27. The ΔE1 values were more than 2.72 when the ceramic veneers were cemented with resin cements in shades of HV+3 and WO. The ΔE2 values of six shades ranged from 0.60-2.56. The shades of HV+3, WO and A3 resin cements were more than 1.60. Different thickness of ceramic materials, resin cement shades and measuring regions could affect the final color of ceramic veneers. The color differences of some resin cements and corresponding try-in pastes might be observed in clinical practice.
[Mh] Termos MeSH primário: Cor
Facetas Dentárias
Cimentos de Resina
Descoloração de Dente/terapia
[Mh] Termos MeSH secundário: Cimentação
Cerâmica
Porcelana Dentária
Temperatura Alta
Seres Humanos
Incisivo
Teste de Materiais
Pressão
Cimentos de Resina/química
Espectrofotometria
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (IPS e.max Press); 0 (Resin Cements); 12001-21-7 (Dental Porcelain); 179240-22-3 (Variolink)
[Em] Mês de entrada:1708
[Cu] Atualização por classe:170801
[Lr] Data última revisão:
170801
[Sb] Subgrupo de revista:D; IM
[Da] Data de entrada para processamento:170304
[St] Status:MEDLINE
[do] DOI:10.3760/cma.j.issn.1002-0098.2017.02.012



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